Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessaxon guidance

SEMA3A RELN LAMA1 GATA3 SEMA4A RYK CNTN2 NOTCH3

1.01e-05285768GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SEMA3A RELN LAMA1 GATA3 SEMA4A RYK CNTN2 NOTCH3

1.03e-05286768GO:0097485
GeneOntologyBiologicalProcessaxonogenesis

SEMA3A RELN LAMA1 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

4.20e-055667610GO:0007409
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SEMA3A RELN CAMK2A LAMA1 CD44 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

4.25e-058197612GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

SEMA3A RELN CAMK2A LAMA1 CD44 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

4.61e-058267612GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SEMA3A RELN CAMK2A LAMA1 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

8.86e-057487611GO:0048667
GeneOntologyBiologicalProcesssympathetic nervous system development

SEMA3A NF1 GATA3

9.20e-0524763GO:0048485
GeneOntologyBiologicalProcessregulation of synaptic plasticity

RELN NF1 CAMK2A UNC13C SPG11 ATP1A3 CNTN2

1.03e-04293767GO:0048167
GeneOntologyBiologicalProcessaxon development

SEMA3A RELN LAMA1 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

1.19e-046427610GO:0061564
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

RELN NF1 ALS2 UNC13C HOMER1

1.28e-04132765GO:0035249
GeneOntologyBiologicalProcessneuron projection morphogenesis

SEMA3A RELN CAMK2A LAMA1 GATA3 ALS2 SPG11 SEMA4A RYK CNTN2 NOTCH3

1.64e-048027611GO:0048812
HumanPhenoArm dystonia

ALS2 SPG11 ATP1A3

3.23e-0514243HP:0031960
HumanPhenoAxial dystonia

PPP2R2B ALS2 SPG11

4.94e-0516243HP:0002530
HumanPhenoHead tremor

PPP2R2B LAMA1 ALS2 SPG11

5.91e-0547244HP:0002346
MousePhenoabnormal CD8-positive, alpha-beta memory T cell number

CD8B CD8B2 CD44 AGK BUD13 TAP1

9.81e-06105666MP:0012774
MousePhenoabnormal CD8-positive, alpha-beta memory T cell morphology

CD8B CD8B2 CD44 AGK BUD13 TAP1

9.81e-06105666MP:0010837
MousePhenoabnormal hippocampus granule cell layer

RELN CAMK2A ATP1A3

1.08e-0420663MP:0008285
MousePhenoabnormal memory T cell number

CD8B CD8B2 CD44 AGK BUD13 TAP1

1.13e-04162666MP:0008048
MousePhenoabnormal memory T cell morphology

CD8B CD8B2 CD44 AGK BUD13 TAP1

1.17e-04163666MP:0010833
DomainGCC2_Rab_bind

RGPD4 RGPD3

3.30e-047752IPR032023
DomainRab_bind

RGPD4 RGPD3

3.30e-047752PF16704
DomainLAM_G_DOMAIN

COL24A1 FAT2 LAMA1

4.74e-0438753PS50025
DomainLaminin_G_2

COL24A1 FAT2 LAMA1

5.52e-0440753PF02210
Domain-

COL24A1 FAT2 LAMA1 ADGRD1

5.79e-04957542.60.120.200
Domain-

RGPD4 RGPD3

7.01e-04107521.10.220.60
DomainGrip

RGPD4 RGPD3

8.55e-0411752SM00755
DomainGRIP

RGPD4 RGPD3

8.55e-0411752PF01465
DomainRan_BP1

RGPD4 RGPD3

1.02e-0312752PF00638
DomainGRIP_dom

RGPD4 RGPD3

1.02e-0312752IPR000237
DomainGRIP

RGPD4 RGPD3

1.02e-0312752PS50913
DomainCRAL_TRIO_2

ARHGAP1 NF1

1.02e-0312752PF13716
DomainRANBD1

RGPD4 RGPD3

1.02e-0312752PS50196
DomainRanBD

RGPD4 RGPD3

1.21e-0313752SM00160
DomainRan_bind_dom

RGPD4 RGPD3

1.21e-0313752IPR000156
DomainLaminin_G

COL24A1 FAT2 LAMA1

1.64e-0358753IPR001791
DomainTF_T-box

TBX3 TBX10

2.08e-0317752IPR001699
DomainTBOX

TBX3 TBX10

2.08e-0317752SM00425
DomainTF_T-box_CS

TBX3 TBX10

2.08e-0317752IPR018186
Domain-

TBX3 TBX10

2.08e-03177522.60.40.820
DomainTBOX_3

TBX3 TBX10

2.08e-0317752PS50252
DomainT-box

TBX3 TBX10

2.08e-0317752PF00907
DomainTBOX_1

TBX3 TBX10

2.08e-0317752PS01283
DomainTBOX_2

TBX3 TBX10

2.08e-0317752PS01264
DomainRCC1

ALS2 HERC3

2.88e-0320752PF00415
DomainSemaphorin

SEMA3A SEMA4A

2.88e-0320752IPR027231
DomainRCC1_1

ALS2 HERC3

3.18e-0321752PS00625
DomainRCC1_2

ALS2 HERC3

3.18e-0321752PS00626
DomainRCC1_3

ALS2 HERC3

3.18e-0321752PS50012
DomainReg_chr_condens

ALS2 HERC3

3.49e-0322752IPR000408
Domain-

ALS2 HERC3

3.49e-03227522.130.10.30
DomainRCC1/BLIP-II

ALS2 HERC3

3.81e-0323752IPR009091
DomainSEC14

ARHGAP1 NF1

4.50e-0325752SM00516
DomainCRAL_TRIO

ARHGAP1 NF1

5.23e-0327752PS50191
DomainCRAL-TRIO_dom

ARHGAP1 NF1

5.62e-0328752IPR001251
DomainSema

SEMA3A SEMA4A

6.86e-0331752SM00630
DomainSemap_dom

SEMA3A SEMA4A

6.86e-0331752IPR001627
DomainSema

SEMA3A SEMA4A

6.86e-0331752PF01403
DomainSEMA

SEMA3A SEMA4A

6.86e-0331752PS51004
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 HDAC9 RGPD3

5.72e-0518603MM1549
Pubmed

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice.

CD8B CD8B2 CD44

6.27e-07879310704459
Pubmed

STAT5 is required for thymopoiesis in a development stage-specific manner.

CD8B CD8B2 CD44

3.17e-061379315294943
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD3 LAMA1

5.03e-061579314697343
Pubmed

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

CD8B CD8B2

5.09e-0627923035575
Pubmed

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

CD8B CD8B2

5.09e-0627923498943
Pubmed

An immunological role for the CD8 beta-chain.

CD8B CD8B2

5.09e-0627921534146
Pubmed

Duality of the murine CD8 compartment.

CD8B CD8B2

5.09e-06279224594598
Pubmed

Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.

CD8B CD8B2

5.09e-0627927889415
Pubmed

AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.

CD8B CD8B2

5.09e-0627923025647
Pubmed

Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

CD8B CD8B2

5.09e-0627922452747
Pubmed

Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.

CD8B CD8B2

5.09e-0627929233619
Pubmed

Stalk region of beta-chain enhances the coreceptor function of CD8.

CD8B CD8B2

5.09e-06279212847256
Pubmed

Transcriptional diversity at the duplicated human CD8 beta loci.

CD8B CD8B2

5.09e-0627928436166
Pubmed

GATA3 rs3824662A allele in B-cell acute lymphoblastic leukemia in adults, adolescents and young adults: association with CRLF2 rearrangement and poor prognosis.

GATA3 CRLF2

5.09e-06279233275800
Pubmed

Structure and expression of the Lyt-3a gene of C.AKR mice.

CD8B CD8B2

5.09e-0627923169881
Pubmed

Esr, a second locus in the house mouse controlling esterase-5.

CD8B CD8B2

5.09e-0627927103930
Pubmed

Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.

CD8B CD8B2

5.09e-0627925558567
Pubmed

Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.

CD8B CD8B2

5.09e-06279212034498
Pubmed

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

CD8B CD8B2

5.09e-0627928108731
Pubmed

Murine Ly-3 restriction fragment length polymorphism and transcript size differences.

CD8B CD8B2

5.09e-0627922576243
Pubmed

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

CD8B CD8B2

5.09e-0627929647223
Pubmed

The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.

CD8B CD8B2

5.09e-062792408079
Pubmed

Characterization of the mouse CD8 beta chain-encoding gene promoter region.

CD8B CD8B2

5.09e-0627928781121
Pubmed

The possible involvement of sema3A and sema4A in the pathogenesis of multiple sclerosis.

SEMA3A SEMA4A

5.09e-06279235460904
Pubmed

Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.

CD8B CD8B2

1.53e-0537923258885
Pubmed

Ly-36: a new mouse lymphocyte alloantigen defined by a Mus musculus molossinus-specific monoclonal antibody and controlled by a gene linked to Ly-2/3 region on chromosome 6.

CD8B CD8B2

1.53e-0537923378837
Pubmed

Evidence for close linkage of a mouse light chain marker with the Ly-2,3 locus.

CD8B CD8B2

1.53e-053792100557
Pubmed

Interaction of the nuclear matrix-associated region (MAR)-binding proteins, SATB1 and CDP/Cux, with a MAR element (L2a) in an upstream regulatory region of the mouse CD8a gene.

CD8B CD8B2

1.53e-0537929218488
Pubmed

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.

CD8B CD8B2

1.53e-05379212810689
Pubmed

A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.

CD8B CD8B2

1.53e-0537929126989
Pubmed

CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation.

CD8B CD8B2

1.53e-05379211754824
Pubmed

The synthesis and processing of beta-glucuronidase in normal and egasyn deficient mouse kidney.

CD8B CD8B2

1.53e-0537927236294
Pubmed

An essential role for the stalk region of CD8 beta in the coreceptor function of CD8.

CD8B CD8B2

1.53e-05379219109142
Pubmed

Recombination between kappa chain genetic markers in the mouse.

CD8B CD8B2

1.53e-0537926437974
Pubmed

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

CD8B CD8B2

1.53e-0537928064243
Pubmed

Role of CD8+ T cells and lymphoid dendritic cells in protection from ocular herpes simplex virus 1 challenge in immunized mice.

CD8B CD8B2

1.53e-05379224807710
Pubmed

Differential susceptibility of mouse Lyt-2 and Lyt-3 genes to negative regulation.

CD8B CD8B2

1.53e-0537928423051
Pubmed

Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments.

CD8B CD8B2

1.53e-0537922784466
Pubmed

Recombination between kappa chain genetic markers and the Lyt-3 locus.

CD8B CD8B2

1.53e-0537926411613
Pubmed

Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.

CD8B CD8B2

1.53e-05379215661911
Pubmed

CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.

CD8B CD8B2

1.53e-05379222081144
Pubmed

Recent duplication of the two human CD8 beta-chain genes.

CD8B CD8B2

1.53e-0537921541829
Pubmed

Zinc is essential for binding of p56(lck) to CD4 and CD8alpha.

CD8B CD8B2

1.53e-0537929830036
Pubmed

Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer.

CD8B CD8B2

1.53e-05379216356863
Pubmed

Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen.

CD8B CD8B2

1.53e-0537924547628
Pubmed

Linkage of a 7S RNA sequence and kappa light chain genes in the mouse.

CD8B CD8B2

1.53e-0537922998983
Pubmed

Molecular biology and function of CD4 and CD8.

CD8B CD8B2

1.53e-0537922493728
Pubmed

A new mouse lymphocyte alloantigen (Ly-35) controlled by the Ly-2/3 region on chromosome 6.

CD8B CD8B2

1.53e-0537923346044
Pubmed

Interleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo.

CD8B CD8B2

1.53e-05379223311920
Pubmed

Reelin signaling pathway genotypes and Alzheimer disease in a Spanish population.

RELN CAMK2A

1.53e-05379224384746
Pubmed

Constitutive CD8 expression drives innate CD8+ T-cell differentiation via induction of iNKT2 cells.

CD8B CD8B2

1.53e-05379231980555
Pubmed

Endobrevin maps to chromosome 2 in human and chromosome 6 in mouse.

CD8B CD8B2

1.53e-0537929878266
Pubmed

Structural basis of the CD8 alpha beta/MHC class I interaction: focused recognition orients CD8 beta to a T cell proximal position.

CD8B CD8B2

1.53e-05379219625641
Pubmed

The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.

CD8B CD8B2

1.53e-05379218929574
Pubmed

Calyculin A inhibits expression of CD8alpha but not CD4 in human peripheral blood T cells.

CD8B CD8B2

1.53e-05379211131152
Pubmed

Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus.

CD8B CD8B2

1.53e-05379210795739
Pubmed

CD8beta knockout mice mount normal anti-viral CD8+ T cell responses--but why?

CD8B CD8B2

1.53e-05379219088062
Pubmed

CD8alpha/alpha homodimers fail to function as co-receptor for a CD8-dependent TCR.

CD8B CD8B2

1.53e-05379217506031
Pubmed

Bop: a new T-cell-restricted gene located upstream of and opposite to mouse CD8b.

CD8B CD8B2

1.53e-0537927590968
Pubmed

Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding.

CD8B CD8B2

1.53e-05379211719190
Pubmed

Genetic polymorphism at the mouse immunoglobulin J kappa locus (Igk-J) as demonstrated by Southern hybridization and nucleotide sequence analysis.

CD8B CD8B2

1.53e-0537922875941
Pubmed

Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement.

CD8B CD8B2

1.53e-05379214568922
Pubmed

The Bop gene adjacent to the mouse CD8b gene encodes distinct zinc-finger proteins expressed in CTLs and in muscle.

CD8B CD8B2

1.53e-0537929013956
Pubmed

The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers.

CD8B CD8B2

1.53e-0537929973530
Pubmed

Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model.

CAMK2A HOMER1

1.53e-05379226670047
Pubmed

Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer.

CD44 NOTCH3

1.53e-05379227035162
Pubmed

TSLP is a negative regulator of RANKL-induced osteoclastogenesis.

TNFSF11 CRLF2

1.53e-05379232600615
Pubmed

Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T-cell coreceptor molecule CD8.

CD8B CD8B2

1.53e-0537927710778
Pubmed

Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding.

CD8B CD8B2

1.53e-05379216951356
Pubmed

Tbr1 regulates differentiation of the preplate and layer 6.

RELN CAMK2A CNTN2

1.93e-052379311239428
Pubmed

Presenilin 1 in migration and morphogenesis in the central nervous system.

RELN GATA3 CNTN2

2.50e-052579315163631
Pubmed

Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction.

CD8B CD8B2

3.05e-05479212459555
Pubmed

The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation.

CD8B CD8B2

3.05e-05479218523287
Pubmed

CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease.

CD8B CD8B2

3.05e-05479221115736
Pubmed

{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.

CD8B CD8B2

3.05e-05479216203967
Pubmed

Crosstalk between ILC2s and Th2 cells varies among mouse models.

GATA3 CRLF2

3.05e-05479236735533
Pubmed

Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families.

SEMA3A RELN

3.05e-05479217684500
Pubmed

Expression Levels of Semaphorins 3A, 3B, 4A, and 4D on Human Peri-implantitis.

SEMA3A SEMA4A

3.05e-05479229763494
Pubmed

CD8α dendritic cells drive establishment of HSV-1 latency.

CD8B CD8B2

3.05e-05479224695322
Pubmed

cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells.

CD8B CD8B2

3.05e-05479224297179
Pubmed

CD8 is needed for development of cytotoxic T cells but not helper T cells.

CD8B CD8B2

3.05e-0547921673361
Pubmed

Ly antigens associated with T cell recognition and effector function.

CD8B CD8B2

3.05e-0547926442265
Pubmed

Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.

TNFSF11 NF1

3.05e-05479217053831
Pubmed

Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3.

CD8B GATA3

3.05e-05479211937547
Pubmed

T cell killing does not require the formation of a stable mature immunological synapse.

CD8B CD8B2

3.05e-05479215048111
Pubmed

CD3 delta establishes a functional link between the T cell receptor and CD8.

CD8B CD8B2

3.05e-05479212215456
Pubmed

Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice.

RELN CNTN2

3.05e-05479216324103
Pubmed

Autoimmune diabetes-prone NOD mice express the Lyt2 alpha (Lyt2.1) and Lyt3 alpha (Lyt3.1) alleles of CD8.

CD8B CD8B2

3.05e-0547928537123
Pubmed

Generation and function of bone marrow-derived dendritic cells from CD4/CD8(-/-) double-knockout mice.

CD8B CD8B2

3.05e-05479210369133
Pubmed

Impairment of T cell development in deltaEF1 mutant mice.

CD8B CD8B2

5.07e-0557929126927
Pubmed

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals.

SEMA3A CNTN2

5.07e-05579218550718
Pubmed

Lmo2 and GATA-3 associated expression in intraembryonic hemogenic sites.

CD44 GATA3

5.07e-05579210631184
Pubmed

Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

CD8B CD8B2

5.07e-05579217082573
Pubmed

CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway.

CD8B CD8B2

5.07e-05579211403253
Pubmed

Chromosomal localization of the genes encoding rat CD4, CD8alpha, and CD8beta.

CD8B CD8B2

5.07e-0557928753864
Pubmed

CD8-β ADP-ribosylation affects CD8(+) T-cell function.

CD8B CD8B2

5.07e-05579223575529
Pubmed

Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons.

RELN CNTN2

5.07e-05579210399933
Pubmed

Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.

CD8B CD8B2

5.07e-05579225427562
Pubmed

A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.

CD8B CD8B2

5.07e-05579225548254
Pubmed

The organization of the immunoglobulin kappa locus in mice.

CD8B CD8B2

5.07e-0557923138071
CytobandEnsembl 112 genes in cytogenetic band chr2q12

RGPD4 CD8B2 RGPD3

3.94e-0482793chr2q12
CytobandXp22.3

SHROOM2 CRLF2

7.23e-0423792Xp22.3
Cytoband1q32.1

PTPN7 ZBED6 CNTN2

8.79e-041087931q32.1
GeneFamilyCadherin related

FAT2 DCHS1

1.20e-031755224
GeneFamilyT-boxes

TBX3 TBX10

1.35e-0318552766
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3A SEMA4A

1.67e-0320552736
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

COL24A1 TNFSF11 MANSC1 PHTF2 SHROOM2 CRLF2

4.27e-071637867f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED24 PTPN7 TNFSF11 HERC3 SEMA4A COG5

6.26e-071747861c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED24 PTPN7 TNFSF11 HERC3 SEMA4A COG5

6.26e-071747865491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCellNS-critical-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3 TNRC6C

1.05e-0619078684f9f5ac29ff0f929a589b76efa61d4c570e76b0
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

PPP2R2B PTPN7 CD8B MAP4K1 GATA3 PHTF2

1.18e-061947865c1dca33f382f37a7deb23e573578343c3b54986
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A RELN TNFSF11 DCHS1 UNC13C

4.14e-06136785e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCell367C-Lymphocytic-ILC-ILC-3|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF136 ZNF394 CD8B GATA3 ATP1A3

7.36e-061537859d64aadbb4bb28469af1d728457b431e21577429
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TBX3 PTPN7 VNN1 CAMK2A ZNF208

8.34e-06157785f6210be2362d833c6d869ff921188bfc85dda11d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN7 CD8B MAP4K1 GATA3 TNRC6C

8.34e-06157785a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TBX3 PTPN7 VNN1 CAMK2A ZNF208

8.34e-0615778543a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

PHTF2 SPG11 COG5 HOMER1 FANCA

8.87e-06159785037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 ZNF394 MAP4K1 GATA3 ADGRD1

9.15e-06160785939e25ef8b64242da2d28ef8342c8eb9cd199f17
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 TBX3 GATA3 PHTF2 NOTCH3

9.43e-061617851b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV5/7_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP2R2B PTPN7 CD8B CD8B2 GATA3

1.06e-05165785207f9ca8839f54710e2112986def4bc7b0ef1a28
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HDAC9 PTPN7 MAP4K1 DPEP3 CRLF2

1.09e-05166785f03f78cae6272c89618c0bda032ce45c4fc96baa
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 TNFSF11 MAP4K1 GATA3 SEMA4A

1.09e-05166785c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCellfacs-Heart-RV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 TNFSF11 MAP4K1 GATA3 SEMA4A

1.09e-0516678533c4876df43b4c1d100699bca47459918bd054d6
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 TNFSF11 MAP4K1 GATA3 SEMA4A

1.09e-05166785ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

HDAC9 TNFSF11 TMEM132D MAP4K1 TAP1

1.19e-05169785a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 TBX3 GATA3 PHTF2 NOTCH3

1.30e-0517278508a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOD1 PTPN7 TNFSF11 MAP4K1 UNC13C

1.30e-051727853ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCellIIH-CD8-CD8_2|IIH / Condition, Cell_class and T cell subcluster

PPP2R2B CD8B CD8B2 CAMK2A TNRC6C

1.30e-051727851466cb4298c63e995b3368d296b254e0e76a1b41
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 TBX3 GATA3 PHTF2 NOTCH3

1.30e-05172785553701349444eb366df3c11f54bb093434f153c6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOD1 PTPN7 TNFSF11 MAP4K1 UNC13C

1.30e-051727852bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

HDAC9 TBX3 GATA3 PHTF2 NOTCH3

1.37e-051747858393f0b43c767839c1630bcb952d62b42efc788d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN7 TNFSF11 CD8B MAP4K1 GATA3

1.49e-051777857d73643beb007032e757f2611121c4f3027aecf5
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 TNFSF11 MAP4K1 GATA3 SEMA4A

1.62e-05180785b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN7 TNFSF11 MAP4K1 GATA3 SEMA4A

1.62e-0518078567b062f2ef7e20f392e00c646f4985c415d40de9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN FAT2 CD44 ATP1A3 FANCA

1.62e-051807856ac62bf1251978c8c12e715f7b73144fca619794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 RELN LAMA1 UNC13C CNTN2

1.80e-051847852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PTPN7 TNFSF11 MAP4K1 GATA3 CRLF2

1.80e-0518478551ae0963b4fb034c3f605ee4e5da513cba7aca35
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 RELN LAMA1 UNC13C CNTN2

1.80e-05184785ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 RELN LAMA1 UNC13C CNTN2

1.80e-051847852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP2R2B PTPN7 CD8B CD8B2 TAP1

1.84e-05185785191d7e9b34bd1598cb4c18e0cb3d018bad83c757
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP2R2B PTPN7 CD8B CD8B2 TAP1

1.84e-0518578599fe59c15c3c0f7afa7e182255e4bacfba346132
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

HDAC9 PPP2R2B RELN ATP1A3 CNTN2

1.84e-05185785d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN7 TNFSF11 RGPD3 CD44 GATA3

1.84e-05185785e1fd66f4295056807aa29c0e4ce6b1a79cc8dfcf
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PTPN7 TNFSF11 GATA3 PHTF2 CRLF2

1.94e-05187785dd5183d2c620b2a87253a9783b70c5df2c36c570
ToppCellNS-critical-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PPP2R2B PTPN7 CD8B MAP4K1 TNRC6C

2.04e-05189785fb7572fb4c7c43886d57a025decad076f32a14c4
ToppCellControl-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.04e-05189785ee4c1d930534788a7759d92dc8ff9c62e6ee2301
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP36 PPP2R2B PTPN7 CD8B GATA3

2.10e-05190785423b54c6d48d6981a9522043252239303dccaf04
ToppCellIPF-Lymphoid-T_Cytotoxic|IPF / Disease state, Lineage and Cell class

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.10e-05190785e5d0186bfb416a3eda76ac12b9379650afb6f409
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN7 TNFSF11 MAP4K1 CD44 GATA3

2.10e-05190785af39d2a46d9502cec69a69b7e8ffef78fc8311c3
ToppCellmetastatic_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|metastatic_Lymph_Node / Location, Cell class and cell subclass

PPP2R2B PTPN7 CD8B GATA3 TAP1

2.10e-05190785cb4cf8ae2156c20b7978ae2e55aa605b4e90f455
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP36 PPP2R2B PTPN7 CD8B GATA3

2.10e-0519078581e7d4f97b958b4ed14298a77104ef31a6ec6c91
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP36 PPP2R2B PTPN7 CD8B GATA3

2.10e-05190785a1b19028c36d192352bc8a7f187790f4b56cfe17
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_CD8+_T|metastatic_Brain / Location, Cell class and cell subclass

PPP2R2B PTPN7 CD8B MAP4K1 TAP1

2.15e-05191785b98367fdb56ccb335d61035e69cd43c61a7fa816
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PTPN7 TNFSF11 GATA3 PHTF2 CRLF2

2.20e-05192785017f613b1b9c0bd0842e5c1e71d3ac60dd89eadd
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP36 PPP2R2B PTPN7 CD8B GATA3

2.20e-05192785dceb8b38c2ddb1a848132bd52edc8e883e7d2aa9
ToppCellIPF-Lymphoid-T_Cytotoxic|World / Disease state, Lineage and Cell class

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.26e-0519378535c902a983d7f1156a74fe68ee366609029833b3
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN7 CD8B MAP4K1 CD44 GATA3

2.32e-05194785c57cf3cc9fc1a682019090369fc1d3adbf37c371
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.37e-05195785fc7a1091c42f09c7630b41f65a704a5350ff7437
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL24A1 TNFSF11 GATA3 UNC13C ADGRD1

2.37e-05195785d70b49f6b9c6c4422adb2936c837a1af7569fb0a
ToppCellHealthy_donor-CD8+_Tem|World / disease group, cell group and cell class (v2)

PPP2R2B PTPN7 CD8B CD8B2 GATA3

2.43e-05196785b04684d319d0c462862677d0f956a389bffef535
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.43e-051967856ad0e6031c6d5743b175ffaf13d4e583aca11021
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.43e-05196785a65d6a2d9eb3fca8faf323dbc4430e53134b7221
ToppCellbackground-T_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PPP2R2B PTPN7 CD8B MAP4K1 CD44

2.43e-05196785b60db71f419caf3705e391e7b6dcf29b406cda9a
ToppCellHealthy/Control-CD8+_Tem|World / Disease group and Cell class

USP36 PTPN7 CD8B CD8B2 GATA3

2.43e-05196785a6dc92476156a695e15373ea57dc04e30014ac55
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN7 CD8B CD8B2 MAP4K1 GATA3

2.49e-05197785adc7bf2120fad4aea58123d882a8cf18ed4174d0
ToppCell5'-Airway_Nasal-Immune_Lymphocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPN7 TNFSF11 CD8B MAP4K1 GATA3

2.49e-0519778540b752b019c95994323c7f65644a6ccf336d327e
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell|390C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R2B PTPN7 CD8B MAP4K1 TAP1

2.49e-05197785e513d448385d5a8dbf68fb2b0892971cd841ae28
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP36 ZNF394 VNN1 ZBED6 CD44

2.49e-051977854a6eff66a17c5e89bda61d887b736f5c62b93bd7
ToppCell(1)_T_CD8_CytT|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.49e-05197785804cec3b1839562dc027a5a2a1e015919bd31de7
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN7 CD8B CD8B2 MAP4K1 GATA3

2.49e-05197785e133bd09efc6d7f539fc1a1ac7a945f07103d6e6
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.55e-051987859dc91a1101eef649a301f0147ecd5c028a9c2b12
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.61e-051997857642a6bc957ecb5953e966ba296b9f4deb368364
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PTPN7 CD8B CD8B2 CD44 GATA3

2.61e-05199785c9e1ac9f0fba23250a5df4052559d18d16df4521
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.61e-051997850486ab11f59f1ef52ddc42094f0f1e65f743a969
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.61e-0519978528b12df9b899784bf405c5d52a0d43fd1a6c6b62
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN7 MAP4K1 CD44 GATA3 ATP1A3

2.61e-051997855a29db2610ba06a2248325a16cad755d20debf2c
ToppCell15-Trachea-Immune-Hematopoietic,_T_Cells|Trachea / Age, Tissue, Lineage and Cell class

PTPN7 CD8B CD44 GATA3 TAP1

2.61e-05199785d5dcf7b4f58a075a7f729165556f7666e6b4c104
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PPP2R2B PTPN7 CD8B CD8B2 GATA3

2.61e-051997851c12b15004fa6ca9ae72a6d6f8f9a5fdeb755bd1
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.61e-05199785f3e8bb9b58a7df3f074e0752af9e1213faef058b
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP2R2B PTPN7 CD8B CD8B2 GATA3

2.61e-05199785c8c89779dda4dcfb26bf86492c2e5a4f158eb8d2
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.61e-05199785ae2b3ca37efb8a7b4a61de279c38c685c138c0b9
ToppCellLung_Parenchyma-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785c57faee6a3d4c73a818c5a25f780741a15b82fc8
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785f2a97e09000801b555edde90ddef25e313e61a31
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-052007858b8c07a16c91bd6e0d276fba1472d0d314e03416
ToppCellBiopsy_IPF-Immune-T_cells|Biopsy_IPF / Sample group, Lineage and Cell type

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785368c7334d211054f1e914a1be4027aa75e2df66c
ToppCellLung_Parenchyma-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-052007854f65e320be904fda16bd305a684e83800dd8e606
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785f7913fddd35932db5b5759995b0576350821bc22
ToppCellBiopsy_Control_(H.)-Immune-T_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-052007853545706d133b29df61affe8ac47b6c9fe85f7775
ToppCell15-Trachea-Immune|Trachea / Age, Tissue, Lineage and Cell class

PTPN7 MAP4K1 CD44 GATA3 TAP1

2.68e-052007858f1c6405de46907097e53e68e43883f21ea4f354
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785a1a4c5cbf4c009d4c09699a16e2d5b814a8751ca
ToppCellParenchyma_COVID-19-Immune-TX-T_cells|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785fe6900541241c77285dd5271d183a246fc3b3c83
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-052007859ef322486e46e4ff05a8cbe06cf8019e996c94b3
ToppCellLung_Parenchyma-Severe-Lymphocyte-T/NK-Other_T-T_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785df4332d3647bdaebb534d923624f05c0e48c49fa
ToppCellLung_Parenchyma-Severe-Lymphocyte-T/NK-Other_T-T_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPP2R2B PTPN7 CD8B MAP4K1 GATA3

2.68e-05200785cf0a3a1bc4b07769f174604a5d3503702e4522ee
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A RELN CD44 UNC13C

4.66e-05113784feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellLPS-IL1RA-Unknown-Endothelial-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELN TNFSF11 DPEP3 NOTCH3

6.91e-051257842938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A TNFSF11 DCHS1 UNC13C

7.13e-05126784a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCelldroplet-Heart-HEART-1m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECR ZNF394 SEMA4A ACOX3

7.35e-05127784983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R2B PTPN7 GATA3 FAM120AOS

1.07e-04140784a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USP36 TMEM132D CD44 KIAA2012

1.16e-041437844a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USP36 TMEM132D CD44 KIAA2012

1.16e-0414378465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

SEMA3A RELN TMEM132D KIAA2012

1.26e-04146784c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

PTPN7 CD8B GATA3 ANKRD52

1.36e-041497842a7f71da51c85e04de2123164914122480e60d66
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Cbln2-Htr2c_(Deep_layer_subiculum)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PTPN7 PLA2G4B ADGRD1

1.37e-045778335494ca30bdafb4c175d74f0b4892098411784b0
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R2B PTPN7 CD8B MAP4K1

1.43e-04151784512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PTPN7 ALS2 KIAA2012 CRLF2

1.47e-04152784faf30245a1690aaa27c7be0832797c340e4af4d7
Drugthioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

MED24 MANSC1 NF1 GATA3 PHTF2 ACOX3 FANCA

3.84e-061917774454_DN
DiseaseJuvenile amyotrophic lateral sclerosis

ALS2 SPG11

1.91e-053752cv:C3468114
DiseaseJuvenile amyotrophic lateral sclerosis

ALS2 SPG11

3.81e-054752C3468114
Diseasebipolar disorder (implicated_via_orthology)

CAMK2A ATP1A3

1.33e-047752DOID:3312 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

MAP4K1 UNC13C ATP1A3 HOMER1 NOTCH3

1.42e-04195755DOID:1574 (implicated_via_orthology)
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

GATA3 CRLF2

4.14e-0412752C0023485
DiseaseMental Retardation, Psychosocial

PECR NAA15 NF1 LAMA1

4.42e-04139754C0025363
DiseaseProfound Mental Retardation

PECR NAA15 NF1 LAMA1

4.42e-04139754C0020796
DiseaseMental deficiency

PECR NAA15 NF1 LAMA1

4.42e-04139754C0917816
DiseaseMental Depression

HDAC9 RELN CAMK2A ATP1A3 HOMER1

4.80e-04254755C0011570
DiseaseCerebrovascular accident

HDAC9 TBX3 NOTCH3

5.36e-0462753C0038454
DiseaseAmyotrophic lateral sclerosis

ALS2 SPG11

8.46e-0417752cv:C0002736
DiseaseDepressive disorder

HDAC9 RELN CAMK2A ATP1A3 HOMER1

8.59e-04289755C0011581
Diseasereasoning

HDAC9 ANKRD52

1.06e-0319752EFO_0004350
DiseaseHodgkin Disease

RELN GATA3

1.42e-0322752C0019829
DiseaseSchizophrenia

SEMA3A HDAC9 ARHGAP1 RELN PLA2G4B LAMA1 TAP1 HOMER1

1.79e-03883758C0036341
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

CD44 SEMA4A

1.99e-0326752C0009405
DiseaseHereditary Nonpolyposis Colorectal Cancer

CD44 SEMA4A

2.48e-0329752C1333990

Protein segments in the cluster

PeptideGeneStartEntry
SKTSPHWKESGASHL

BUD13

296

Q9BRD0
HWKESGASHLSFPKN

BUD13

301

Q9BRD0
FSKKILHTAWHPSEN

PPP2R2B

411

Q00005
HFFSTLKEWPQTHQA

AGK

236

Q53H12
HALASASKPLASWTT

ACOX3

401

O15254
LSPWDKSSHSAHRVD

ADGRD1

856

Q6QNK2
AQFSTHHVFPLATLW

ALS2

946

Q96Q42
RKWTPLHAAAASGHT

ANKRD52

651

Q8NB46
AFKSSTPHNVSWRHE

CASP12

266

Q6UXS9
TKFEEDHLSHYSPWS

RC3H2

826

Q9HBD1
SVKHILFSAWPDHQT

PTPN7

246

P35236
FFSPIHLHSNVAWTV

MISP

606

Q8IVT2
AHTHWFSIDPTSGII

DCHS1

516

Q96JQ0
SATHPTVKLFWETFH

HERC3

956

Q15034
PLEGILSSSAWHFTH

FAT2

21

Q9NYQ8
PKFLHTNSTSHTWPF

MORC3

16

Q14149
QFLSPAEHISSKGWH

PECR

111

Q9BY49
NSSDAKATPFWSHLL

FAM214B

276

Q7L5A3
HSTLWFPEGFSLHKD

NOTCH3

1671

Q9UM47
SASEALKHPWLSDHK

MYLK4

351

Q86YV6
DHSWLPSDKSHITFC

KIAA2012

311

Q0VF49
HHTDYSKPTDISWRD

MANSC1

156

Q9H8J5
HPHFSTWKATTLDGL

PLA2G4B

586

P0C869
WEKLISFSHHGPNAT

PRSS54

281

Q6PEW0
SPKHVRFSWHQDAVT

CRLF2

121

Q9HC73
LPFSHSSAISKHWEA

HOMER1

171

Q86YM7
KRAFAIDSSHPWLHE

NAA15

696

Q9BXJ9
SHVSHLPTTNLSFIW

RELN

131

P78509
LNSSKSASHHRWPTE

RGPD3

831

A6NKT7
HTRFSQWLDDHPSEK

COG5

781

Q9UP83
KALGSHHTASPWNLS

GATA3

101

P23771
HHTASPWNLSPFSKT

GATA3

106

P23771
PSSDSHHEFLTLWDS

CD8B2

61

A6NJW9
SWLFLPSESKNHLHT

CD44

246

P16070
PSSDSHHEFLALWDS

CD8B

61

P10966
QWAIHEHFLPESSAS

FANCA

956

O15360
VLSTSPFHPATHWKQ

PRMT6

306

Q96LA8
HASHDPTMDLTFTWT

CNTN2

531

Q02246
FDKSSHTWVALSHIA

ATP1A3

401

P13637
FKRFPAHLSTHWVAD

ACOD1

271

A6NK06
FHPATAKPLSWQHSK

AHCTF1

831

Q8WYP5
KSPVLHTHSFSDLQW

CCDC168

5166

Q8NDH2
TASHLDWTAHSPELL

DNAAF5

571

Q86Y56
STPWAESSTKFRHHM

DPEP3

226

Q9H4B8
WYTAAHHTSLDQSSP

HDAC9

176

Q9UKV0
FLSSATPVHSKAWHR

OLAH

126

Q9NV23
LVPSETNFLHFTWHA

RYK

101

P34925
TAAWTHPSTKDQHLL

MAP4K1

501

Q92918
PSHFLDISEDWSLHT

PLAC1

191

Q9HBJ0
LNSSKSASHHRWPTE

RGPD4

831

Q7Z3J3
WLHSSHPGLEKISAI

PHTF2

451

Q8N3S3
SHTQASLSHELWKVP

TNRC6C

1451

Q9HCJ0
KHGFTLAFPSDHATW

TBX3

216

O15119
HHWSPVLISLAALFS

TMEM132D

11

Q14C87
VSHPALLSDGKWHTV

LAMA1

2786

P25391
LPSTWSLHAHGLAKE

FAM120AOS

206

Q5T036
HILPGLLTDSSKWHS

MED24

786

O75448
HHGLTSDNKPSLSWL

ARHGAP1

126

Q07960
WLHHDASFVAAIPST

SEMA4A

226

Q9H3S1
SWHATKFSDSHPELA

SHROOM2

116

Q13796
DSTRLLHWGSHPTAF

TAP1

126

Q03518
HDSRWLNDPKFISAH

SEMA3A

216

Q14563
ALLDTSVQHSPHFDW

INTS5

211

Q6P9B9
TAAEALKHPWISHRS

CAMK2A

261

Q9UQM7
SWHKATFLFHTQEPN

COL24A1

1671

Q17RW2
WSHLPHFSSPDLVNK

SPG11

1176

Q96JI7
ASTSKTPAWLHHQLL

TBX10

296

O75333
WHVLKPHKSDSGDSF

ZNF394

326

Q53GI3
WKPFSSHHSFRTHEI

ZNF136

146

P52737
VLPHLSAVEFHSAWA

VNN1

241

O95497
THYADATPLWHSQSD

UNC13C

526

Q8NB66
QWAHLPHDLSKASFL

SPPL2B

51

Q8TCT7
HDVSESTHWTPFLNA

GPLD1

81

P80108
AFSWPSSLTEHKRIH

ZNF728

376

P0DKX0
HKPVADTHWSSLNLT

NF1

1551

P21359
PSGSHKVSLSSWYHD

TNFSF11

176

O14788
TADASLSKHSSVFHW

ZNF644

941

Q9H582
LSKHSSVFHWTDLSL

ZNF644

946

Q9H582
PSTRAKTSIVWHFFH

ZBED6

126

P86452
FSWPSRLTEHKATHA

ZNF208

1066

O43345
PSISHEAHKTSLSSW

UNQ5830/PRO19650/PRO19816

16

Q6UY13
SPSEFRWAELKLHAH

VN1R3

111

Q9BXE9
DAHWPVSYATTHSKA

THEGL

401

P0DJG4
NFWSVTHPAKAASLS

USP36

1106

Q9P275
FPAKVTAHWHKGTTL

TRAPPC5

156

Q8IUR0