Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 GPRC5D NMUR2 TAS2R46 OR6X1 ADGRD1

7.41e-078845613GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR12D3 ERBB4 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 GPRC5D NMUR2 TAS2R46 OR6X1 ADGRD1 CHRND

3.12e-0613535615GO:0004888
GeneOntologyMolecularFunctionchannel activity

GJB5 GJB4 SCN3A SCN4A TRPV6 NMUR2 TRPV5 CHRND

1.01e-04525568GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GJB5 GJB4 SCN3A SCN4A TRPV6 NMUR2 TRPV5 CHRND

1.03e-04526568GO:0022803
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

1.15e-046562GO:0034647
GeneOntologyMolecularFunctionolfactory receptor activity

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.94e-04431567GO:0004984
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

2.14e-048562GO:0032453
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR12D3 OR4P4 OR4C11 GJB4 OR10AD1 OR4Q3 OR10K2 TAS2R46 OR6X1

1.52e-05547569GO:0007606
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 GPRC5D NMUR2 TAS2R46 ADCY5 OR6X1 ADGRD1

1.54e-0513955614GO:0007186
GeneOntologyBiologicalProcesssensory perception of smell

OR12D3 OR4P4 OR4C11 GJB4 OR10AD1 OR4Q3 OR10K2 OR6X1

3.45e-05465568GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 TAS2R46 OR6X1

4.65e-05485568GO:0050907
GeneOntologyBiologicalProcessspermatid development

ADGB CFAP47 PSME4 NUP210L CCR6 SPAG17

7.57e-05262566GO:0007286
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 TAS2R46 OR6X1

8.00e-05524568GO:0009593
GeneOntologyBiologicalProcessspermatid differentiation

ADGB CFAP47 PSME4 NUP210L CCR6 SPAG17

9.30e-05272566GO:0048515
GeneOntologyBiologicalProcessG-quadruplex DNA unwinding

WRN DNA2

1.51e-047562GO:0044806
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.61e-04432567GO:0050911
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 TAS2R46 OR6X1

1.65e-04582568GO:0050906
GeneOntologyBiologicalProcesstelomere maintenance via semi-conservative replication

WRN DNA2

2.57e-049562GO:0032201
GeneOntologyBiologicalProcessgamete generation

FANCD2 ADGB CFAP47 EED PSME4 NUP210L RACGAP1 BIRC3 CCR6 SPAG17

2.77e-049825610GO:0007276
GeneOntologyBiologicalProcesscell cycle checkpoint signaling

FANCD2 USP44 USP28 DNA2 TRRAP

3.04e-04217565GO:0000075
GeneOntologyBiologicalProcessgerm cell development

ADGB CFAP47 EED PSME4 NUP210L CCR6 SPAG17

3.14e-04482567GO:0007281
GeneOntologyBiologicalProcessDNA repair

FANCD2 USP44 FANCB PSME4 USP28 WRN DNA2 TRRAP

3.41e-04648568GO:0006281
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

ADGB CFAP47 EED PSME4 NUP210L CCR6 SPAG17

5.36e-04527567GO:0022412
GeneOntologyBiologicalProcesssensory perception

OR12D3 OR4P4 OR4C11 GJB4 OR10AD1 OR4Q3 OR10K2 NMUR2 TAS2R46 OR6X1

5.53e-0410725610GO:0007600
DomainTRPV5/TRPV6

TRPV6 TRPV5

8.83e-062562IPR008344
DomainConnexin303

GJB5 GJB4

8.83e-062562IPR002271
DomainConnexin311

GJB5 GJB4

8.83e-062562IPR002270
DomainGPCR_Rhodpsn_7TM

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 NMUR2 OR6X1

2.64e-056705610IPR017452
Domain7tm_1

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 NMUR2 OR6X1

2.89e-056775610PF00001
DomainG_PROTEIN_RECEP_F1_1

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 NMUR2 OR6X1

3.19e-056855610PS00237
DomainG_PROTEIN_RECEP_F1_2

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 NMUR2 OR6X1

3.44e-056915610PS50262
DomainGPCR_Rhodpsn

OR12D3 OR4P4 GPR18 OR4C11 OR10AD1 OR4Q3 OR10K2 CCR6 NMUR2 OR6X1

3.48e-056925610IPR000276
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

5.28e-054562IPR013637
DomainPLU-1

KDM5C KDM5D

5.28e-054562PF08429
Domainzf-C5HC2

KDM5C KDM5D

8.78e-055562PF02928
DomainZnf_C5HC2

KDM5C KDM5D

8.78e-055562IPR004198
DomainOlfact_rcpt

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.65e-04393567IPR000725
DomainIon_trans_dom

SCN3A SCN4A TRPV6 TRPV5

3.79e-04114564IPR005821
DomainIon_trans

SCN3A SCN4A TRPV6 TRPV5

3.79e-04114564PF00520
DomainNa_channel_asu

SCN3A SCN4A

3.91e-0410562IPR001696
DomainJmjN

KDM5C KDM5D

3.91e-0410562SM00545
DomainJMJN

KDM5C KDM5D

3.91e-0410562PS51183
DomainNa_trans_assoc

SCN3A SCN4A

3.91e-0410562IPR010526
DomainJmjN

KDM5C KDM5D

3.91e-0410562PF02375
DomainJmjN

KDM5C KDM5D

3.91e-0410562IPR003349
DomainNa_trans_assoc

SCN3A SCN4A

3.91e-0410562PF06512
DomainTRP_channel

TRPV6 TRPV5

4.77e-0411562IPR004729
DomainARM-type_fold

KPNA4 URB1 PSME4 DOCK11 HEATR1 TRRAP

5.17e-04339566IPR016024
Domain-

KDM5C KDM5D

9.04e-04155621.10.150.60
DomainBRIGHT

KDM5C KDM5D

9.04e-0415562SM00501
DomainARID_dom

KDM5C KDM5D

9.04e-0415562IPR001606
DomainARID

KDM5C KDM5D

9.04e-0415562PS51011
DomainARID

KDM5C KDM5D

9.04e-0415562PF01388
DomainCONNEXINS_1

GJB5 GJB4

1.46e-0319562PS00407
DomainCONNEXINS_2

GJB5 GJB4

1.62e-0320562PS00408
DomainConnexin

GJB5 GJB4

1.62e-0320562IPR000500
DomainConnexin_CCC

GJB5 GJB4

1.62e-0320562IPR019570
DomainConnexin_N

GJB5 GJB4

1.62e-0320562IPR013092
DomainConnexin

GJB5 GJB4

1.62e-0320562PF00029
DomainConnexin_CCC

GJB5 GJB4

1.62e-0320562SM01089
DomainConnexin_CS

GJB5 GJB4

1.62e-0320562IPR017990
DomainCNX

GJB5 GJB4

1.62e-0320562SM00037
DomainIQ

ADGB SCN3A SCN4A

1.85e-0381563SM00015
DomainJmjC

KDM5C KDM5D

2.34e-0324562PF02373
DomainIQ_motif_EF-hand-BS

ADGB SCN3A SCN4A

2.49e-0390563IPR000048
DomainIQ

ADGB SCN3A SCN4A

2.74e-0393563PS50096
DomainJMJC

KDM5C KDM5D

4.13e-0332562PS51184
DomainJmjC_dom

KDM5C KDM5D

4.13e-0332562IPR003347
DomainJmjC

KDM5C KDM5D

4.39e-0333562SM00558
Domain-

KPNA4 PSME4 HEATR1 TRRAP

4.40e-032225641.25.10.10
DomainARM-like

KPNA4 PSME4 HEATR1 TRRAP

8.71e-03270564IPR011989
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.23e-0634056711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.23e-0634056711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.31e-0634356732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR12D3 OR4P4 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

1.39e-0634656714611657
Pubmed

Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.

TRPV6 TRPV5

2.55e-06256220178461
Pubmed

Ubiquitin-specific peptidase 28 enhances STAT3 signaling and promotes cell growth in non-small-cell lung cancer.

USP28 STAT3

2.55e-06256230881015
Pubmed

The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.

TRPV6 TRPV5

2.55e-06256222354706
Pubmed

Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.

TRPV6 TRPV5

2.55e-06256216564089
Pubmed

Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.

TRPV6 TRPV5

2.55e-06256219295174
Pubmed

Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.

TRPV6 TRPV5

2.55e-06256223968883
Pubmed

Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.

TRPV6 TRPV5

2.55e-06256212390878
Pubmed

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

TRPV6 TRPV5

2.55e-06256212574114
Pubmed

Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.

TRPV6 TRPV5

2.55e-06256211549322
Pubmed

[TRPV5 and TRPV6 calcium channels in human T cells].

TRPV6 TRPV5

2.55e-06256219140341
Pubmed

TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.

TRPV6 TRPV5

2.55e-06256230916584
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

2.55e-06256210441747
Pubmed

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

TRPV6 TRPV5

2.55e-06256216565876
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

2.55e-06256216416087
Pubmed

Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.

TRPV6 TRPV5

2.55e-06256216705151
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

2.55e-06256232081420
Pubmed

Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.

TRPV6 TRPV5

2.55e-06256220405023
Pubmed

A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.

TRPV6 TRPV5

2.55e-06256211846401
Pubmed

First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.

TRPV6 TRPV5

2.55e-06256225164318
Pubmed

Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.

TRPV6 TRPV5

2.55e-06256224761864
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

2.55e-0625629060413
Pubmed

Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

TRPV6 TRPV5

2.55e-06256215123711
Pubmed

Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.

TRPV6 TRPV5

2.55e-06256212077127
Pubmed

Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.

TRPV6 TRPV5

2.55e-06256211719848
Pubmed

Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.

TRPV6 TRPV5

2.55e-06256217233615
Pubmed

[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].

TRPV6 TRPV5

2.55e-06256224592736
Pubmed

Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2.

BIRC3 STAT3

2.55e-06256215845643
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

2.55e-0625627524912
Pubmed

Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin.

GJB5 GJB4

2.55e-0625621512260
Pubmed

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.

TRPV6 TRPV5

7.63e-06356227291418
Pubmed

STAT3-induced upregulation of circCCDC66 facilitates the progression of non-small cell lung cancer by targeting miR-33a-5p/KPNA4 axis.

KPNA4 STAT3

7.63e-06356232151944
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

7.63e-0635627544442
Pubmed

Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.

TRPV6 TRPV5

7.63e-06356216763551
Pubmed

Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.

WRN DNA2

7.63e-06356227612385
Pubmed

Investigation of JAK2, STAT3 and CCR6 polymorphisms and their gene-gene interactions in inflammatory bowel disease.

CCR6 STAT3

7.63e-06356222269120
Pubmed

DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.

FANCD2 DNA2

7.63e-06356222987153
Pubmed

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.

TRPV6 TRPV5

7.63e-06356216354700
Pubmed

Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.

USP28 STAT3

7.63e-06356236442624
Pubmed

DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.

WRN DNA2

7.63e-06356225122754
Pubmed

Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

TRPV6 TRPV5

7.63e-06356217200157
Pubmed

Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma.

CCR6 STAT3

7.63e-06356226789110
Pubmed

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.

FANCD2 DNA2

7.63e-06356237526271
Pubmed

A GTPase-activating protein binds STAT3 and is required for IL-6-induced STAT3 activation and for differentiation of a leukemic cell line.

RACGAP1 STAT3

7.63e-06356215284113
Pubmed

Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.

TRPV6 TRPV5

7.63e-06356219922080
Pubmed

Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

TRPV6 TRPV5

7.63e-06356216380433
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5C KDM5D

1.52e-05456216541399
Pubmed

STAT3 and Oct-3/4 control histone modification through induction of Eed in embryonic stem cells.

EED STAT3

1.52e-05456218201968
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5C KDM5D

1.52e-05456217320160
Pubmed

Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

TRPV6 TRPV5

1.52e-05456212660155
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5C KDM5D

1.52e-05456232732223
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5C KDM5D

1.52e-0545627951230
Pubmed

Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).

TRPV6 TRPV5

2.54e-05556222407925
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN3A SCN4A

2.54e-05556217724025
Pubmed

Role and regulation of TRP channels in neutrophil granulocytes.

TRPV6 TRPV5

2.54e-05556212765698
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

KPNA4 ADGB EED NUP210L ZBTB25 HEATR1 DDX39A TRRAP

2.67e-0575456835906200
Pubmed

Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier.

CCR6 STAT3

3.80e-05656222304915
Pubmed

CCR6 regulates the migration of inflammatory and regulatory T cells.

CCR6 STAT3

5.32e-05756219050256
Pubmed

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.

TRPV6 TRPV5

7.09e-05856233859252
Pubmed

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.

CCR6 STAT3

7.09e-05856219249008
Pubmed

X-linked inheritance of Fanconi anemia complementation group B.

FANCD2 FANCB

7.09e-05856215502827
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN3A SCN4A

9.10e-05956216382098
Pubmed

ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.

USP44 EED

9.10e-05956229669287
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN3A SCN4A

9.10e-05956215746173
Pubmed

A balance between elongation and trimming regulates telomere stability in stem cells.

WRN DNA2

1.14e-041056227918544
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

EED KDM5C KDM5D TRRAP

1.22e-0415756430186101
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

KPNA4 ERBB4 PSME4 DDX39A STAT3

1.31e-0430456532235678
Pubmed

Multiple members of the connexin gene family participate in preimplantation development of the mouse.

GJB5 GJB4

1.39e-04115628631157
Pubmed

Two interactive genes responsible for a new inherited cataract (RCT) in the mouse.

GJB5 GJB4

1.39e-041156211309658
Pubmed

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.

DOCK11 RACGAP1

1.39e-041156225074804
Pubmed

Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

ERBB4 CHRND

1.39e-041156212403715
Pubmed

mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse.

GJB5 GJB4

1.39e-041156215255617
Pubmed

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

FANCD2 FANCB

1.39e-041156219965384
Pubmed

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

FANCD2 FANCB

1.66e-041256216116422
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5C KDM5D

1.96e-041356214660691
Pubmed

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.

KPNA4 STAT3

1.96e-041356234950606
Pubmed

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway.

FANCD2 FANCB

1.96e-041356227986371
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5C KDM5D

1.96e-041356224619213
Pubmed

Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos.

TRPV6 TRPV5

1.96e-041356222266179
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

KPNA4 FANCD2 URB1 USP28 HEATR1 DNA2 STAT3

2.02e-0475456733060197
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

URB1 EED WRN RACGAP1 HEATR1 DDX39A TRRAP

2.10e-0475956735915203
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK11 RACGAP1

2.29e-041456212432077
Pubmed

The human olfactory receptor gene family.

OR12D3 OR4C11 OR10AD1 OR4Q3 OR10K2 OR6X1

2.31e-0454156614983052
Pubmed

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.

FANCD2 FANCB

2.64e-041556219536649
Pubmed

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice.

GJB5 GJB4

2.64e-041556234639052
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN3A CHRND

2.64e-04155629726281
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

KDM5C KDM5D

2.64e-041556214762062
Pubmed

Esophageal Atresia / Tracheoesophageal Fistula Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

FANCD2 FANCB

3.01e-041656220301753
Pubmed

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

FANCD2 FANCB

3.01e-041656227760317
Pubmed

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass.

EED KDM5C

3.41e-041756221471155
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

KPNA4 FANCD2 PSME4 TRRAP

3.78e-0421156417314511
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

KDM5C KDM5D

3.83e-041856212023983
Pubmed

An expression atlas of connexin genes in the mouse.

GJB5 GJB4

3.83e-041856215081111
Pubmed

The novel mouse connexin39 gene is expressed in developing striated muscle fibers.

GJB5 GJB4

3.83e-041856215466892
Pubmed

Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.

OR4C11 OR10AD1

3.83e-041856220550939
Pubmed

An update on connexin genes and their nomenclature in mouse and man.

GJB5 GJB4

4.28e-041956214681012
Pubmed

Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.

RACGAP1 STAT3

4.28e-041956221041952
InteractionNRG2 interactions

FANCD2 ERBB4 DDX39A

5.63e-077523int:NRG2
InteractionZNF532 interactions

KPNA4 FANCD2 ERBB4 KDM5C

6.62e-0727524int:ZNF532
InteractionSLC25A22 interactions

FANCD2 EED KDM5C BIRC3 TRRAP

1.55e-05122525int:SLC25A22
InteractionTRRAP interactions

KPNA4 FANCD2 ADGB EED NUP210L ZBTB25 KDM5C HEATR1 DDX39A TRRAP

2.87e-057905210int:TRRAP
CytobandEnsembl 112 genes in cytogenetic band chr11q11

OR4P4 OR4C11

1.11e-0340562chr11q11
GeneFamilySodium voltage-gated channel alpha subunits

SCN3A SCN4A

2.46e-0494821203
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

7.09e-0415482418
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

FANCD2 FANCB

1.27e-0320482548
GeneFamilyGap junction proteins

GJB5 GJB4

1.54e-0322482314
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

1.84e-0324482485
GeneFamilyTransient receptor potential cation channels

TRPV6 TRPV5

2.50e-0328482249
GeneFamilyOlfactory receptors, family 4

OR4P4 OR4C11 OR4Q3

4.86e-03129483151
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

HEATR1 KDM5D

8.10e-0351482870
GeneFamilyUbiquitin specific peptidases

USP44 USP28

9.70e-0356482366
GeneFamilyOlfactory receptors, family 10

OR10AD1 OR10K2

1.33e-0266482157
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGB SCN3A KDM5D SPAG17 CFAP46

1.28e-0615056553de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGB SCN3A KDM5D SPAG17 CFAP46

1.28e-06150565e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellfacs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMCO4 GPR18 CLEC10A DNA2 TRRAP

2.89e-06177565f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 FANCB LAMA3 RACGAP1 DNA2

3.05e-0617956588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 FANCB SCN3A RACGAP1 DNA2

3.14e-06180565401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP47 ERBB4 SPAG17 CFAP46

3.59e-061855655e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 FANCB LAMA3 RACGAP1 DNA2

3.78e-061875659351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

ADGB CFAP47 SPAG17 CFAP46

3.91e-051515648216462e723fec2797387929dde095370947e10a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 ADGB TRPV6 DNA2

4.33e-0515556451f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 ADGB TRPV6 DNA2

4.33e-0515556423dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

GJB5 GJB4 TRPV6 ADGRD1

4.44e-05156564574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

GJB5 GJB4 TRPV6 ADGRD1

4.44e-05156564605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMCO4 CYB561D2 OR10K2 CCR6

4.78e-05159564ba82d1f55dd77c4b2183981b76cab1480fba75ad
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR18 BIRC3 CCR6 TAS2R46

5.14e-05162564b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ADGB CFAP47 SPAG17 CFAP46

5.39e-05164564fd30c55d0d75ef8b9396435d836187168095152b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 LAMA3 RACGAP1 DNA2

5.52e-0516556488681101d7cf60b99b8ace5d8c0944323b937306
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB5 GJB4 LAMA3 TRPV6

5.92e-0516856403896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP47 SPAG17 CFAP46

6.06e-05169564fba841664939c771881ba97f14ef1df6635c04ff
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FANCB GPR18 GJB4 CCR6

6.34e-05171564c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FANCB GPR18 GJB4 CCR6

6.34e-0517156455b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADGB CFAP47 SPAG17 CFAP46

6.34e-0517156452aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 NUP210L BIRC3 CCR6

6.78e-05174564ce9bdd02dc8eb45ba9c1481619c0089b465e6442
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

GALNTL6 SCN3A BIRC3 CCR6

7.25e-05177564f54691e5558091c1734ab15153a10bff15ed171e
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGB CFAP47 SPAG17 CFAP46

7.25e-051775643cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGB CFAP47 SPAG17 CFAP46

7.25e-0517756412a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

7.41e-05178564de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

7.57e-05179564666072c0e8448dbaec1683d18368ec2502453f90
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB5 GJB4 JPH2 ADGRD1

7.74e-051805643d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB5 GJB4 JPH2 ADGRD1

7.74e-0518056447e345359064dc8ceec982b062e47802e728b43f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPR18 SCN3A WRN KDM5D

7.90e-05181564986c036e656f24fe374807e2711cec9e3c83c892
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 ERBB4 DOCK11 LAMA3

7.90e-0518156435bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 ERBB4 DOCK11 LAMA3

7.90e-0518156470eff83dd85691e977972c660731394d2fcf5cdf
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR18 SCN3A BIRC3 CCR6

7.90e-05181564d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

7.90e-05181564dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

8.07e-051825647ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

FANCD2 FANCB RACGAP1 DNA2

8.07e-051825649adf90bb2808f234d53b89ca0ae07380478204ad
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ADGB CFAP47 SPAG17 CFAP46

8.07e-05182564fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADGB CFAP47 SPAG17 CFAP46

8.07e-05182564000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TMCO4 PSME4 SCN4A CCR6

8.07e-0518256403992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

FANCD2 FANCB RACGAP1 GPRC5D

8.25e-05183564f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FANCD2 FANCB RACGAP1 DNA2

8.25e-05183564df8568751205313d149939ea2683097e3652a60b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

8.42e-051845649690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

FANCD2 FANCB RACGAP1 TRPV5

8.42e-05184564f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

8.42e-051845645daff849625f2f41d56615569c0ed59cd733b34c
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

FANCD2 FANCB RACGAP1 DNA2

8.60e-051855649766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 LAMA3 RACGAP1 DDX39A

8.60e-0518556430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

8.60e-0518556430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

8.60e-051855643e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ADGB CFAP47 SPAG17 CFAP46

8.60e-0518556418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 DOCK11 BIRC3 CCR6

8.60e-05185564e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

8.78e-05186564d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB CFAP47 SPAG17 CFAP46

8.78e-05186564f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP47 SPAG17 CFAP46

8.78e-0518656485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|390C / Donor, Lineage, Cell class and subclass (all cells)

ADGB CFAP47 SPAG17 CFAP46

8.78e-05186564708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADGB CFAP47 SPAG17 CFAP46

8.78e-05186564029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 USP44 ERBB4 DOCK11

8.78e-051865646379609b7ace80683f5754b16aa77f11b43766ae
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

8.96e-05187564f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellControl-Lymphocyte-B-B_intermediate|Control / Disease, Lineage and Cell Type

GALNTL6 GPR18 BIRC3 CCR6

8.96e-0518756490c9b1a51539838323325f563be4adf5fdf1b38f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

8.96e-051875649e10ed56090d82589bc457788282f664b70ace4b
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN3A JPH2 SPAG17 ADCY5

8.96e-051875648ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR18 BIRC3 CCR6 GPRC5D

8.96e-051875648089ae6ee59533a090fe0b19bdd057fba8fa11de
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

GALNTL6 ERBB4 JPH2 ADCY5

8.96e-0518756478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

ADGB CFAP47 SPAG17 CFAP46

9.15e-0518856426326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

9.15e-0518856461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

9.15e-0518856434b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ERBB4 TRPV6 SPAG17 TRPV5

9.15e-051885648f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

9.15e-051885642b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

9.15e-051885644154f4787483c7e076e87a187733a9f666742c3d
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGB CFAP47 SPAG17 CFAP46

9.34e-05189564a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

9.34e-0518956468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CFAP47 SPAG17 CFAP46

9.34e-05189564dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

9.34e-05189564c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

9.34e-051895648ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

9.34e-0518956490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.34e-05189564a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

ADGB CFAP47 SPAG17 CFAP46

9.34e-05189564b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

ADGB CFAP47 SPAG17 CFAP46

9.34e-0518956427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

9.34e-051895643e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.34e-0518956493b1026bb1ba759e5704561c9a5de14a30c08894
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.53e-0519056417829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SCN3A TRPV6 TRPV5

9.53e-051905644836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-Cycling_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FANCD2 RACGAP1 DNA2 DDX39A

9.73e-051915645d4fed25bd318472a17228b12ade4c331865bda5
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GPR18 SCN3A BIRC3 CCR6

9.73e-051915648dda37ebf74b587129795f61541cc511ec97a314
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.73e-05191564e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCN3A JPH2 ADCY5 ADGRD1

9.73e-0519156404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.73e-051915649d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

ADGB CCR6 SPAG17 CFAP46

9.73e-05191564e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB CFAP47 SPAG17 CFAP46

9.73e-051915641c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ERBB4 SCN3A TRPV6 TRPV5

9.92e-05192564760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCN3A JPH2 ADCY5 ADGRD1

9.92e-05192564bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

ERBB4 SCN3A TRPV6 TRPV5

9.92e-05192564d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCN3A JPH2 ADCY5 ADGRD1

9.92e-05192564b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-13|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR18 SCN3A BIRC3 CCR6

9.92e-05192564e5ab932b4c2fed538161281ae07dfcdd82706fdd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB CFAP47 SPAG17 CFAP46

9.92e-051925641b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

9.92e-05192564d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

9.92e-05192564eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

9.92e-05192564354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

1.01e-041935640e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CFAP47 SPAG17 CFAP46

1.01e-04193564ea345d34440b25f65358a53dc72831998d1c3620
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB CFAP47 SPAG17 CFAP46

1.01e-04193564ad58f5080e0ba65c845056ea6b79037b636e9c64
Drughydrochlorothiazide

SCN3A SCN4A TRPV6 TRPV5 ADCY5

1.15e-05120565CID000003639
Druggaliellalactone

KPNA4 STAT3

1.78e-053562ctd:C416043
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A

1.78e-053562ctd:C561228
Drugresiniferatoxin

SCN3A SCN4A JPH2 TRPV5

2.11e-0566564CID000104826
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

1.89e-054532DOID:0060809 (implicated_via_orthology)
DiseaseWerner syndrome (implicated_via_orthology)

WRN DNA2

3.15e-055532DOID:5688 (implicated_via_orthology)
Diseaseleukemia

FANCD2 BIRC3 STAT3

1.34e-0455533C0023418
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN3A SCN4A

1.41e-0410532DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN3A SCN4A

1.41e-0410532DOID:0080422 (implicated_via_orthology)
Diseasecolon cancer (is_marker_for)

KDM5C BIRC3 STAT3

1.66e-0459533DOID:219 (is_marker_for)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN3A SCN4A

2.07e-0412532DOID:0060170 (implicated_via_orthology)
Diseaseskin melanoma (is_marker_for)

FANCD2 STAT3

2.44e-0413532DOID:8923 (is_marker_for)
DiseaseFanconi anemia

FANCD2 FANCB

2.84e-0414532cv:C0015625
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

FANCB STAT3

3.27e-0415532DOID:5520 (is_implicated_in)
Diseaseschizophrenia (biomarker_via_orthology)

ERBB4 KDM5C

3.27e-0415532DOID:5419 (biomarker_via_orthology)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

3.74e-0416532DOID:0050888 (implicated_via_orthology)
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

SCN4A CHRND

3.74e-0416532C0751885
Diseasealcohol use disorder (implicated_via_orthology)

ERBB4 KDM5C KDM5D CHRND

4.20e-04195534DOID:1574 (implicated_via_orthology)
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

SCN4A CHRND

4.23e-0417532C0751883
DiseaseBone marrow hypocellularity

FANCD2 FANCB

4.75e-0418532C1855710
DiseaseCongenital Myasthenic Syndromes, Presynaptic

SCN4A CHRND

5.31e-0419532C0751884
Diseaseneck circumference

GALNTL6 USP44

5.31e-0419532EFO_0011043
DiseaseMyasthenic Syndromes, Congenital

SCN4A CHRND

8.52e-0424532C0751882
DiseaseFanconi Anemia

FANCD2 FANCB

9.25e-0425532C0015625
DiseaseFEV change measurement, response to zileuton

CYP21A2 CCR6

9.25e-0425532EFO_0005921, EFO_0007676
DiseasePancytopenia

FANCD2 FANCB

1.00e-0326532C0030312
DiseaseAcute monocytic leukemia

FANCD2 FANCB

1.00e-0326532C0023465
DiseaseMiller Dieker syndrome

FANCD2 FANCB

1.25e-0329532C0265219
DiseaseMental deterioration

GALNTL6 ERBB4

1.25e-0329532HP_0001268
Diseaserenal cell carcinoma (is_marker_for)

ERBB4 BIRC3 STAT3

1.59e-03128533DOID:4450 (is_marker_for)
DiseaseAbnormality of radial ray

FANCD2 FANCB

1.61e-0333532C4228778
DiseaseCardiomyopathies

JPH2 ADCY5 STAT3

1.67e-03130533C0878544

Protein segments in the cluster

PeptideGeneStartEntry
TIQLVTQLMPHGCLL

ERBB4

791

Q15303
INILVPCVLISFMVN

CHRND

251

Q07001
CTHLTNFAILMQVVP

ADGRD1

541

Q6QNK2
TLPICILHIVNNDTM

ADGB

1026

Q8N7X0
IEPVNGQVTVLVMCH

DDX39A

106

O00148
TLLVQVLVCFMPFHI

GPR18

236

Q14330
LVFLACQIPHNMVLL

CCR6

261

P51684
MCLHELTVPVLQLGV

CFAP46

1471

Q8IYW2
RMALFQHLTCVIPIL

BIRC3

451

Q13489
CFVQITIVPHSIFML

ADCY5

776

O95622
DVCFITTTIPQMLIH

OR10AD1

71

Q8NGE0
VPNTILICMVILLNI

JPH2

671

Q9BR39
MARFLLHQVCIIPIE

LAMA3

1026

Q16787
VCLVILQHQAMKTPT

NMUR2

66

Q9GZQ4
LNVMPVLDQSVLCHI

KDM5D

466

Q9BY66
HCSVILKMQPFQVRL

CYP21A2

466

P08686
LLIMISITCTQLIHQ

OR4P4

41

Q8NGL7
HSIMQVILVIQLPFC

OR4Q3

156

Q8NH05
IIRIINPITMQCIKH

EED

171

O75530
PTIMSQQVCIILIVL

OR4C11

131

Q6IEV9
FTIVFCQTMLLIQLP

OR6X1

151

Q8NH79
TVIMNPQVCILLAAA

OR12D3

131

Q9UGF7
VMFQCLHNLIRILPI

FANCB

726

Q8NB91
DDVPINCTMVLLHIV

DOCK11

886

Q5JSL3
MTPCQLNVDFVVLLV

GPRC5D

161

Q9NZD1
LILVTCPSLLVVMHV

GJB4

81

Q9NTQ9
SNQVVVCLLPFMVIN

HEATR1

596

Q9H583
LILVTCPSLLVVMHV

GJB5

81

O95377
QLIVATTCMGINHPI

DNA2

736

P51530
DCSLMLTPKQIHQVI

CFAP47

736

Q6ZTR5
VLCPVLTSLVIMNQV

CYB561D2

196

O14569
VFQLLTPMCNHLENI

FANCD2

1016

Q9BXW9
KVLLPATLMLCHVQF

NUP210L

1606

Q5VU65
QIVIFMLCTLVLAIP

OR10K2

196

Q6IF99
VMVLAQPTKICEQHV

GARIN3

86

Q8TC56
LNQIALNHKTIVCPM

GALNTL6

246

Q49A17
PLLFLVCHLFVINMN

TAS2R46

136

P59540
AIPSIMNVLLVCLIF

SCN4A

1156

P35499
VLVCHMTSLLQVPLE

TMCO4

136

Q5TGY1
MLAPLLEVIKHFCQT

WRN

1211

Q14191
AIPSIMNVLLVCLIF

SCN3A

1331

Q9NY46
MIPSIVVHCVNEIEQ

RACGAP1

361

Q9H0H5
VICLYQKVVPHVVMQ

URB1

561

O60287
ISVPLILHCMLEQVV

SPAG17

441

Q6Q759
MLLTIIHIIQIPCAV

ABCA8

1096

O94911
VCVPVHSEMLLRVQQ

CLEC10A

141

Q8IUN9
MIFIHQTSECIKIQP

ZBTB25

51

P24278
THSLPVVVISNICQM

STAT3

456

P40763
HILILQPNKTFACQM

TRPV6

241

Q9H1D0
INVMNELIIPCIHLI

USP28

976

Q96RU2
FVQCIIQPVLLAMFS

PSME4

396

Q14997
MKICSAIINLFHLIP

TRRAP

1511

Q9Y4A5
PVVLTEAQKQLMICH

USP44

551

Q9H0E7
EAQKQLMICHLPQVL

USP44

556

Q9H0E7
HILILQPNKTFACQM

TRPV5

201

Q9NQA5
VQAVIDANLVPMIIH

KPNA4

361

O00629
LNVMPVLEQSVLCHI

KDM5C

476

P41229