Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

TGFBR1 LTBP1 ACVR1C

4.70e-0520713GO:0004675
GeneOntologyMolecularFunctionhistone H3K36 dimethyltransferase activity

NSD2 NSD1

7.44e-054712GO:0140954
GeneOntologyMolecularFunctionactivin receptor activity, type I

TGFBR1 ACVR1C

1.24e-045712GO:0016361
GeneOntologyMolecularFunctionhistone modifying activity

RNF168 KDM5A NSD2 NSD1 KDM1B SUV39H2

1.64e-04229716GO:0140993
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5A KDM1B

1.85e-046712GO:0034647
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

TGFBR1 CRIM1 LTBP1 ACVR1C

2.39e-0485714GO:0019199
GeneOntologyMolecularFunctionchromatin binding

RNF168 POLR1A KDM5A NSD2 TLE1 MCM9 NSD1 KDM1B ADNP SUV39H2

2.72e-047397110GO:0003682
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5A KDM1B

3.44e-048712GO:0032453
GeneOntologyMolecularFunctionactivin receptor activity

TGFBR1 ACVR1C

4.42e-049712GO:0017002
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

NSD2 NSD1 SUV39H2

5.14e-0444713GO:0140938
GeneOntologyMolecularFunctionhistone H4K20 methyltransferase activity

NSD2 NSD1

5.51e-0410712GO:0042799
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FBN1 VWF TECTB LTBP1 FBN3

5.52e-04188715GO:0005201
GeneOntologyMolecularFunctionactivin binding

TGFBR1 ACVR1C

8.04e-0412712GO:0048185
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

NSD2 NSD1

9.48e-0413712GO:0046975
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

TGFBR1 LTBP1

9.48e-0413712GO:0005024
GeneOntologyMolecularFunctioncalcium ion binding

FBN1 NOTCH2NLB SLIT3 LRP1 LTBP1 ATP2A2 FBN3 NOTCH2 C2CD5

1.30e-03749719GO:0005509
GeneOntologyMolecularFunctionhistone H4 methyltransferase activity

NSD2 NSD1

1.64e-0317712GO:0140939
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

NSD2 NSD1 SUV39H2

1.83e-0368713GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

NSD2 NSD1 SUV39H2

1.91e-0369713GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

NSD2 NSD1 SUV39H2

2.07e-0371713GO:0042054
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RFPL4B TRAF7 RNF168 TRIM31 TRIM22 MUL1

2.08e-03372716GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RFPL4B TRAF7 RNF168 TRIM31 TRIM22 MUL1

2.91e-03398716GO:0061659
GeneOntologyMolecularFunctiontransition metal ion binding

TRAF7 POLR1A KDM5A FECH TRIM31 NSD1 ZNF205 KDM1B ADNP SUV39H2 TRIM22

3.03e-0311897111GO:0046914
GeneOntologyMolecularFunctionSMAD binding

TGFBR1 ACVR1C ZEB2

3.57e-0386713GO:0046332
GeneOntologyMolecularFunctiontransforming growth factor beta binding

TGFBR1 LTBP1

3.83e-0326712GO:0050431
GeneOntologyMolecularFunctionzinc ion binding

TRAF7 POLR1A KDM5A TRIM31 NSD1 ZNF205 KDM1B SUV39H2 TRIM22

4.20e-03891719GO:0008270
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5A KDM1B

4.44e-0328712GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5A KDM1B

5.42e-0331712GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5A KDM1B

5.77e-0332712GO:0140457
GeneOntologyMolecularFunctionsulfur compound binding

GREM2 FBN1 SLIT3 LRP1 SUV39H2

5.85e-03323715GO:1901681
GeneOntologyMolecularFunctionprotein methyltransferase activity

NSD2 NSD1 SUV39H2

5.91e-03103713GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

NSD2 NSD1 SUV39H2

6.23e-03105713GO:0008170
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

GREM2 FBN1 LTBP1

6.32e-0611713GO:0035581
GeneOntologyBiologicalProcesscardiac septum development

TGFBR1 NSD2 SLIT3 LRP1 LTBP1 NOTCH2

6.81e-06134716GO:0003279
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

GREM2 FBN1 LTBP1

1.09e-0513713GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

GREM2 FBN1 LTBP1

1.09e-0513713GO:1900116
GeneOntologyBiologicalProcesspositive regulation of protein sumoylation

TRAF7 SAE1 MUL1

2.12e-0516713GO:0033235
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

GREM2 TGFBR1 FBN1 CRIM1 LRP1 LTBP1 ACVR1C ZEB2 NOTCH2

2.13e-05445719GO:0141091
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

GREM2 TGFBR1 FBN1 CRIM1 LRP1 LTBP1 ZEB2 NOTCH2

2.50e-05347718GO:0090092
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

GREM2 TGFBR1 FBN1 CRIM1 LRP1 LTBP1 ACVR1C ZEB2 NOTCH2

3.97e-05482719GO:0007178
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 LTBP1

6.98e-054712GO:0035583
GeneOntologyBiologicalProcessdevelopmental cell growth

ADRA1A ZFYVE27 SLIT3 LRP1 ADNP MUL1 ZEB2

7.86e-05301717GO:0048588
GeneOntologyBiologicalProcesscardiac chamber development

TGFBR1 NSD2 SLIT3 LRP1 LTBP1 NOTCH2

9.02e-05212716GO:0003205
GeneOntologyBiologicalProcessregulation of protein sumoylation

TRAF7 SAE1 MUL1

1.20e-0428713GO:0033233
GeneOntologyBiologicalProcesscardiac septum morphogenesis

TGFBR1 NSD2 SLIT3 NOTCH2

2.52e-0489714GO:0060411
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

TGFBR1 TRAF7 SALL2 RNF168 KDM5A NSD2 TLE1 TLE3 NSD1 ZNF205 SUV39H2 TRIM22 ZEB2 NOTCH2

2.54e-0413997114GO:0045892
GeneOntologyBiologicalProcessventricular septum development

TGFBR1 NSD2 SLIT3 LTBP1

2.75e-0491714GO:0003281
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

TGFBR1 TRAF7 SALL2 RNF168 KDM5A NSD2 TLE1 TLE3 NSD1 ZNF205 SUV39H2 TRIM22 ZEB2 NOTCH2

2.82e-0414137114GO:1902679
GeneOntologyBiologicalProcesscell growth

TGFBR1 ADRA1A ZFYVE27 LMX1A SLIT3 LRP1 ADNP MUL1 ZEB2

2.84e-04625719GO:0016049
GeneOntologyBiologicalProcessregulation of protein localization

TRAF7 LYPD1 FBN1 RNF168 POLR1A NSD2 LRP1 SAE1 ACVR1C ABLIM3 TRIM22 C2CD5

3.10e-0410877112GO:0032880
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 LTBP1

3.23e-048712GO:0071694
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TGFBR1 FBN1 LRP1 LTBP1 ACVR1C ZEB2

3.76e-04276716GO:0007179
GeneOntologyBiologicalProcessneuron projection morphogenesis

ZFYVE27 LMX1A SLIT3 LRP1 ITGA1 LRRC4C ADNP MUL1 ZEB2 NOTCH2

4.03e-048027110GO:0048812
GeneOntologyBiologicalProcesspositive regulation of intracellular signal transduction

TGFBR1 TRAF7 ADRA1A VWF LRP1 MIOS USP4 ITGA1 TRIM22 MUL1 ZEB2 NOTCH2 TFF2

4.37e-0412997113GO:1902533
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

ZFYVE27 LMX1A SLIT3 LRP1 ITGA1 LRRC4C ADNP MUL1 ZEB2 NOTCH2

4.75e-048197110GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

ZFYVE27 LMX1A SLIT3 LRP1 ITGA1 LRRC4C ADNP MUL1 ZEB2 NOTCH2

5.07e-048267110GO:0048858
GeneOntologyBiologicalProcessregulation of axonogenesis

ZFYVE27 LRP1 LRRC4C ADNP ZEB2

5.25e-04192715GO:0050770
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

GREM2 FBN1 CRIM1 LRP1 LTBP1 ZEB2 NOTCH2

5.34e-04412717GO:0090287
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

ZFYVE27 SLIT3 LRP1 ADNP MUL1 ZEB2

5.74e-04299716GO:0060560
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

GREM2 TGFBR1 FBN1 ZFYVE27 CRIM1 LRP1 LTBP1 ACVR1C ZEB2 NOTCH2

6.34e-048507110GO:0071363
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

ZFYVE27 LRP1 ADNP ZEB2

6.47e-04114714GO:0050772
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

GREM2 TGFBR1 FBN1 ZFYVE27 CRIM1 LRP1 LTBP1 ITGA1 ACVR1C ZEB2 NOTCH2 C2CD5

6.77e-0411867112GO:0007167
GeneOntologyBiologicalProcessaxonogenesis

ZFYVE27 LMX1A SLIT3 LRP1 LRRC4C ADNP ZEB2 NOTCH2

7.13e-04566718GO:0007409
GeneOntologyBiologicalProcessneuron projection extension

ZFYVE27 SLIT3 LRP1 ADNP MUL1

7.38e-04207715GO:1990138
GeneOntologyBiologicalProcessregulation of cellular localization

TRAF7 LYPD1 FBN1 RNF168 POLR1A NSD2 LRP1 SAE1 ACVR1C ABLIM3 TRIM22 C2CD5

8.19e-0412127112GO:0060341
GeneOntologyBiologicalProcesspositive regulation of cell growth

TGFBR1 ZFYVE27 LRP1 ADNP MUL1

8.39e-04213715GO:0030307
GeneOntologyBiologicalProcessresponse to growth factor

GREM2 TGFBR1 FBN1 ZFYVE27 CRIM1 LRP1 LTBP1 ACVR1C ZEB2 NOTCH2

8.49e-048837110GO:0070848
GeneOntologyBiologicalProcessregulation of osteoclast development

FBN1 NOTCH2

8.89e-0413712GO:2001204
GeneOntologyBiologicalProcesspositive regulation of axon extension

ZFYVE27 LRP1 ADNP

9.02e-0455713GO:0045773
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

GREM2 FBN1 CRIM1 LRP1 LTBP1

9.31e-04218715GO:0090101
GeneOntologyBiologicalProcessventricular septum morphogenesis

TGFBR1 NSD2 SLIT3

9.51e-0456713GO:0060412
GeneOntologyCellularComponentmicrofibril

FBN1 LTBP1 FBN3

1.05e-0513713GO:0001527
GeneOntologyCellularComponentactivin receptor complex

TGFBR1 ACVR1C

1.69e-046712GO:0048179
HumanPhenoAbnormal pulmonary artery morphology

TGFBR1 TRAF7 FBN1 POLR1A LTBP1 ZEB2 NOTCH2

2.29e-06133257HP:0030966
HumanPhenoAortic valve stenosis

TRAF7 FBN1 VWF LTBP1 ZEB2 NOTCH2

1.31e-05113256HP:0001650
HumanPhenoBowing of the legs

FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

1.77e-05254258HP:0002979
HumanPhenoCraniosynostosis

TGFBR1 TRAF7 FBN1 POLR1A NSD1 LTBP1 ZEB2

2.44e-05190257HP:0001363
HumanPhenoAbnormal aortic valve physiology

TGFBR1 TRAF7 FBN1 VWF LTBP1 ZEB2 NOTCH2

2.61e-05192257HP:0031652
HumanPhenoPulmonary artery dilatation

TGFBR1 FBN1 POLR1A

3.67e-0514253HP:0004927
HumanPhenoAbnormal sternum morphology

TGFBR1 TRAF7 FBN1 NSD2 NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

4.00e-054742510HP:0000766
HumanPhenoAbnormal aortic valve morphology

TGFBR1 TRAF7 FBN1 VWF POLR1A LTBP1 ZEB2 NOTCH2

4.51e-05289258HP:0001646
HumanPhenoAbnormal mitral valve morphology

TGFBR1 TRAF7 FBN1 VWF POLR1A ADNP

5.65e-05146256HP:0031477
HumanPhenoAbnormal heart valve physiology

TGFBR1 TRAF7 FBN1 VWF POLR1A LTBP1 ADNP ZEB2 NOTCH2

7.22e-05403259HP:0031653
HumanPhenoInguinal hernia

TGFBR1 TRAF7 FBN1 POLR1A NSD1 LTBP1 ADNP NOTCH2

7.81e-05312258HP:0000023
HumanPhenoBowing of the long bones

FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

8.55e-05316258HP:0006487
HumanPhenoAnomaly of the limb diaphyses

FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

9.77e-05322258HP:0006504
HumanPhenoHyperdeviation

FBN1 SALL2

1.38e-044252HP:0025587
HumanPhenoHypertropia

FBN1 SALL2

1.38e-044252HP:0025586
HumanPhenoAbnormal diaphysis morphology

FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

1.53e-04343258HP:0000940
HumanPhenoAbnormal mitral valve morphology

TGFBR1 TRAF7 FBN1 VWF POLR1A ADNP NOTCH2

1.68e-04257257HP:0001633
HumanPhenoEctopia pupillae

FBN1 NSD2 ZEB2

1.98e-0424253HP:0009918
HumanPhenoBicuspid aortic valve

TGFBR1 TRAF7 FBN1 POLR1A ZEB2

2.34e-04119255HP:0001647
HumanPhenoAbnormality of the pulmonary artery

TGFBR1 TRAF7 FBN1 POLR1A LTBP1 ZEB2 NOTCH2

2.51e-04274257HP:0004414
HumanPhenoAbnormal heart valve morphology

TGFBR1 TRAF7 FBN1 VWF POLR1A NSD2 LTBP1 ADNP ZEB2 NOTCH2

2.52e-045882510HP:0001654
HumanPhenoAbnormal aortic valve cusp morphology

TGFBR1 TRAF7 FBN1 POLR1A ZEB2

2.53e-04121255HP:0031567
HumanPhenoHernia

TGFBR1 TRAF7 FBN1 POLR1A NSD2 NSD1 DYNC2I1 LTBP1 ADNP NOTCH2

2.56e-045892510HP:0100790
HumanPhenoAbnormality of the calf

FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

3.34e-04384258HP:0002981
HumanPhenoAbnormality of cranial sutures

TGFBR1 TRAF7 FBN1 POLR1A NSD1 LTBP1 ZEB2 NOTCH2

3.59e-04388258HP:0011329
HumanPhenoDownslanted palpebral fissures

TGFBR1 FBN1 POLR1A NSD2 NSD1 LTBP1 ADNP ZEB2 NOTCH2

3.65e-04497259HP:0000494
HumanPhenoHernia of the abdominal wall

TGFBR1 TRAF7 FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP NOTCH2

4.17e-04506259HP:0004299
HumanPhenoAbdominal wall defect

TGFBR1 TRAF7 FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP NOTCH2

4.50e-04511259HP:0010866
HumanPhenoThoracoabdominal wall defect

TGFBR1 TRAF7 FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP NOTCH2

4.50e-04511259HP:0100656
HumanPhenoAbnormality of the tubular bones

TGFBR1 FBN1 POLR1A NSD2 NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

4.58e-046322510HP:0100713
HumanPhenoAbnormality of the long tubular bones

TGFBR1 FBN1 POLR1A NSD2 NSD1 DYNC2I1 LTBP1 ADNP ZEB2 NOTCH2

4.58e-046322510HP:0100714
HumanPhenoIncreased arm span

FBN1 NSD1

4.78e-047252HP:0012771
HumanPhenoCavum septum pellucidum

POLR1A NSD2 NSD1

5.65e-0434253HP:0002389
HumanPhenoAbnormal cardiac ventricle morphology

TGFBR1 TRAF7 FBN1 POLR1A VEZF1 NSD2 NSD1 DYNC2I1 LTBP1 ZEB2 NOTCH2

5.72e-047802511HP:0001713
HumanPhenoAbnormal cardiac septum morphology

TGFBR1 TRAF7 FBN1 POLR1A VEZF1 NSD2 NSD1 DYNC2I1 ADNP ZEB2 NOTCH2

6.19e-047872511HP:0001671
HumanPhenoPulmonary artery aneurysm

TGFBR1 POLR1A

6.36e-048252HP:0004937
HumanPhenoPulmonary artery stenosis

POLR1A LTBP1 ZEB2 NOTCH2

6.68e-0484254HP:0004415
HumanPhenoAtrial septal defect

TGFBR1 TRAF7 POLR1A VEZF1 NSD2 NSD1 ADNP ZEB2 NOTCH2

6.88e-04541259HP:0001631
HumanPhenoAbnormality of the atrial septum

TGFBR1 TRAF7 POLR1A VEZF1 NSD2 NSD1 ADNP ZEB2 NOTCH2

6.88e-04541259HP:0001630
HumanPhenoAbnormal atrial septum morphology

TGFBR1 TRAF7 POLR1A VEZF1 NSD2 NSD1 ADNP ZEB2 NOTCH2

7.17e-04544259HP:0011994
HumanPhenoAbnormality of the abdominal wall

TGFBR1 TRAF7 FBN1 POLR1A NSD1 DYNC2I1 LTBP1 ADNP NOTCH2

8.87e-04560259HP:0004298
HumanPhenoAbnormal acetabulum morphology

FBN1 POLR1A LRP1 DYNC2I1

9.43e-0492254HP:0003170
HumanPhenoDisproportionate tall stature

TGFBR1 FBN1 NSD2

9.84e-0441253HP:0001519
MousePhenoabnormal ascending aorta morphology

TGFBR1 FBN1 LTBP1 ATP2A2

1.85e-0622584MP:0009867
Domain-

RFPL4B TRAF7 GTF2E1 ZFYVE27 RNF168 KDM5A NSD2 TRIM31 NSD1 TRIM22 MUL1

4.48e-0744966113.30.40.10
DomainZnf_RING/FYVE/PHD

RFPL4B TRAF7 GTF2E1 ZFYVE27 RNF168 KDM5A NSD2 TRIM31 NSD1 TRIM22 MUL1

5.57e-074596611IPR013083
DomainEGF_Ca-bd_CS

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

1.19e-0697666IPR018097
DomainGrowth_fac_rcpt_

FBN1 CRIM1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

1.28e-06156667IPR009030
DomainEGF_CA

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

1.34e-0699666PS01187
DomainTB

FBN1 LTBP1 FBN3

1.46e-067663PF00683
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

2.00e-06106666IPR000152
DomaincEGF

FBN1 LRP1 LTBP1 FBN3

2.01e-0626664IPR026823
DomaincEGF

FBN1 LRP1 LTBP1 FBN3

2.01e-0626664PF12662
Domain-

FBN1 LTBP1 FBN3

2.33e-0686633.90.290.10
DomainTB

FBN1 LTBP1 FBN3

3.49e-069663PS51364
DomainTB_dom

FBN1 LTBP1 FBN3

3.49e-069663IPR017878
DomainEGF_CA

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

4.53e-06122666SM00179
DomainEGF-like_Ca-bd_dom

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

4.98e-06124666IPR001881
DomainRING

RFPL4B TRAF7 RNF168 NSD2 TRIM31 NSD1 TRIM22 MUL1

1.16e-05305668SM00184
DomainEGF_CA

FBN1 LRP1 LTBP1 FBN3 NOTCH2

1.32e-0586665PF07645
DomainZnf_RING

RFPL4B TRAF7 RNF168 NSD2 TRIM31 NSD1 TRIM22 MUL1

1.88e-05326668IPR001841
DomainPost-SET_dom

NSD2 NSD1 SUV39H2

2.28e-0516663IPR003616
DomainPostSET

NSD2 NSD1 SUV39H2

2.28e-0516663SM00508
DomainPOST_SET

NSD2 NSD1 SUV39H2

2.28e-0516663PS50868
DomainASX_HYDROXYL

FBN1 LRP1 LTBP1 FBN3 NOTCH2

2.74e-05100665PS00010
DomainFBN

FBN1 FBN3

3.68e-053662IPR011398
DomainCT

GREM2 VWF SLIT3

6.19e-0522663SM00041
DomainEGF

SLIT3 LRP1 LTBP1 FBN3 NOTCH2

8.30e-05126665PF00008
DomainCys_knot_C

GREM2 VWF SLIT3

9.17e-0525663IPR006207
DomainCTCK_2

GREM2 VWF SLIT3

9.17e-0525663PS01225
DomainAWS

NSD2 NSD1

1.22e-045662SM00570
DomainGroucho_enhance

TLE1 TLE3

1.22e-045662IPR009146
DomainTLE_N

TLE1 TLE3

1.22e-045662PF03920
DomainAWS

NSD2 NSD1

1.22e-045662PS51215
DomainAWS_dom

NSD2 NSD1

1.22e-045662IPR006560
DomainGroucho/TLE_N

TLE1 TLE3

1.22e-045662IPR005617
DomainEGF_3

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

1.80e-04235666PS50026
DomainEGF

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

1.80e-04235666SM00181
DomainEGF-like_dom

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

2.46e-04249666IPR000742
DomainGS

TGFBR1 ACVR1C

2.55e-047662SM00467
DomainGS_dom

TGFBR1 ACVR1C

2.55e-047662IPR003605
DomainGS

TGFBR1 ACVR1C

2.55e-047662PS51256
DomainTGF_beta_GS

TGFBR1 ACVR1C

2.55e-047662PF08515
DomainEGF_1

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

2.80e-04255666PS00022
DomainEGF-like_CS

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

3.17e-04261666IPR013032
DomainEGF_2

FBN1 SLIT3 LRP1 LTBP1 FBN3 NOTCH2

3.43e-04265666PS01186
DomainSET

NSD2 NSD1 SUV39H2

4.08e-0441663PF00856
DomainActivin_recp

TGFBR1 ACVR1C

5.43e-0410662IPR000472
DomainActivin_recp

TGFBR1 ACVR1C

5.43e-0410662PF01064
DomainZF_RING_1

RFPL4B TRAF7 RNF168 TRIM31 TRIM22 MUL1

5.64e-04291666PS00518
DomainSET

NSD2 NSD1 SUV39H2

5.74e-0446663SM00317
DomainZF_RING_2

RFPL4B TRAF7 RNF168 TRIM31 TRIM22 MUL1

6.38e-04298666PS50089
DomainZnf_C2H2/integrase_DNA-bd

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

7.14e-04694669IPR013087
DomainSET_dom

NSD2 NSD1 SUV39H2

7.34e-0450663IPR001214
DomainSET

NSD2 NSD1 SUV39H2

7.34e-0450663PS50280
DomainTGFB_receptor

TGFBR1 ACVR1C

7.93e-0412662IPR000333
DomainLRRNT

SLIT3 LRRC4C LRRC4

8.70e-0453663PF01462
DomainZINC_FINGER_C2H2_2

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

1.55e-03775669PS50157
DomainZinc_finger_PHD-type_CS

KDM5A NSD2 NSD1

1.57e-0365663IPR019786
DomainZINC_FINGER_C2H2_1

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

1.58e-03777669PS00028
DomainCTCK_1

VWF SLIT3

1.81e-0318662PS01185
DomainZnf_FYVE_PHD

ZFYVE27 KDM5A NSD2 NSD1

1.82e-03147664IPR011011
DomainZnf_C2H2-like

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

1.86e-03796669IPR015880
DomainZnf_C2H2

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

2.01e-03805669IPR007087
DomainVWC_out

VWF CRIM1

2.02e-0319662SM00215
DomainZnF_C2H2

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ADNP ZNF501 ZEB2

2.06e-03808669SM00355
DomainPWWP

NSD2 NSD1

2.24e-0320662SM00293
DomainPHD

KDM5A NSD2 NSD1

2.37e-0375663PF00628
DomainWD40

TRAF7 TLE1 TLE3 MIOS DYNC2I1

2.57e-03268665SM00320
Domain-

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ZNF501 ZEB2

2.62e-036796683.30.160.60
DomainZnf_RING_CS

RFPL4B TRAF7 TRIM31 TRIM22

2.65e-03163664IPR017907
DomainWD40_repeat

TRAF7 TLE1 TLE3 MIOS DYNC2I1

2.74e-03272665IPR001680
DomainZnf_PHD-finger

KDM5A NSD2 NSD1

2.75e-0379663IPR019787
DomainPWWP

NSD2 NSD1

2.97e-0323662PF00855
DomainPWWP_dom

NSD2 NSD1

2.97e-0323662IPR000313
DomainWD_REPEATS_1

TRAF7 TLE1 TLE3 MIOS DYNC2I1

3.00e-03278665PS00678
DomainWD_REPEATS_2

TRAF7 TLE1 TLE3 MIOS DYNC2I1

3.05e-03279665PS50082
DomainWD_REPEATS_REGION

TRAF7 TLE1 TLE3 MIOS DYNC2I1

3.05e-03279665PS50294
DomainPWWP

NSD2 NSD1

3.23e-0324662PS50812
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

TGFBR1 FBN1 LTBP1 FBN3

2.47e-0625554M39713
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

TGFBR1 FBN1 LTBP1 ZEB2

8.05e-0559554M39886
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

GREM2 TGFBR1 FBN1 LTBP1 ACVR1C

9.40e-05118555MM15588
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 LTBP1 FBN3

3.98e-0437553M27134
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

GREM2 TGFBR1 FBN1 LTBP1 ACVR1C

4.01e-04161555M27871
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP1

4.12e-048552M47850
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

TGFBR1 FBN1 LTBP1

4.30e-0438553MM14874
PathwayWP_EUKARYOTIC_TRANSCRIPTION_INITIATION

GTF2E1 GTF2H3 POLR1A

5.79e-0442553M39386
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM5A NSD2 NSD1 KDM1B SUV39H2

5.86e-04175555MM14941
PathwayWP_EUKARYOTIC_TRANSCRIPTION_INITIATION

GTF2E1 GTF2H3 POLR1A

6.21e-0443553MM15919
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE1 TLE3

6.59e-0410552MM15156
PathwayKEGG_LYSINE_DEGRADATION

NSD2 NSD1 SUV39H2

6.65e-0444553M13720
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 LTBP1 FBN3

6.65e-0444553M26969
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

NSD2 NSD1 SUV39H2

7.58e-0446553MM14933
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

TGFBR1 FBN1 LTBP1

8.07e-0447553M646
PathwayWP_TGFBETA_SIGNALING_PATHWAY

TGFBR1 LTBP1 ZEB2

1.15e-0353553MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

TGFBR1 LTBP1 ZEB2

1.28e-0355553M39351
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE1 TLE3

1.32e-0314552M27402
Pubmed

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.

TLE1 TLE3 NOTCH2

8.13e-0857131303260
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

GTF2E1 RNF168 VEZF1 KDM5A NSD2 NSD1 KDM1B ADNP SUV39H2 ZEB2

4.39e-07608711036089195
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

TLE1 TLE3 NOTCH2

1.33e-061171315499562
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SALL2 KDM5A TLE1 TLE3 ZNF516 LRP1 ADNP ZEB2

2.24e-0641871834709266
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

TLE1 TLE3 NOTCH2

3.64e-06157139291577
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

GTF2H3 RNF168 NSD1 SAE1 KDM1B ATP2A2 TRIM22 MUL1

4.04e-0645371829656893
Pubmed

The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.

FBN1 LTBP1

4.11e-06271228669633
Pubmed

Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications.

KDM5A KDM1B

4.11e-06271231160694
Pubmed

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis.

NSD2 NSD1

4.11e-06271229176703
Pubmed

Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition.

TGFBR1 USP4

4.11e-06271230335615
Pubmed

The transcriptional co-repressor TLE3 regulates development of trophoblast giant cells lining maternal blood spaces in the mouse placenta.

TLE3 NOTCH2

4.11e-06271223954203
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

4.11e-06271215221638
Pubmed

Groucho/TLE family proteins and transcriptional repression.

TLE1 TLE3

4.11e-06271210831834
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

FBN1 LRP1

4.11e-06271224484584
Pubmed

Differential functions of TLE1 and TLE3 depending on a specific phosphorylation site.

TLE1 TLE3

4.11e-06271233571907
Pubmed

Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes.

LRP1 ATP2A2

4.11e-06271225968337
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

FBN1 VWF CRIM1 LRP1 LTBP1

4.49e-0611871521078624
Pubmed

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification.

SALL2 LMX1A TECTB

1.06e-052171332492250
Pubmed

Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs.

TGFBR1 LTBP1

1.23e-05371231196201
Pubmed

Relation between transforming growth factor-β1 expression, its receptor and clinicopathological factors and survival in HER2-negative gastric cancers.

TGFBR1 LTBP1

1.23e-05371222015652
Pubmed

The NSD family of protein methyltransferases in human cancer.

NSD2 NSD1

1.23e-05371225942451
Pubmed

Targeted genetic analysis in a large cohort of familial and sporadic cases of aneurysm or dissection of the thoracic aorta.

TGFBR1 FBN1

1.23e-05371229543232
Pubmed

microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression.

USP4 ZEB2

1.23e-05371224798342
Pubmed

Shear stress-independent binding of von Willebrand factor-type 2B mutants p.R1306Q & p.V1316M to LRP1 explains their increased clearance.

VWF LRP1

1.23e-05371225728415
Pubmed

The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.

NSD2 NSD1

1.23e-05371237150325
Pubmed

Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.

TLE1 TLE3

1.23e-0537128808280
Pubmed

The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.

NSD2 NSD1

1.23e-05371235532818
Pubmed

Dural ectasia in individuals with Marfan-like features but exclusion of mutations in the genes FBN1, TGFBR1 and TGFBR2.

TGFBR1 FBN1

1.23e-05371220662850
Pubmed

Application of next-generation sequencing to screen for pathogenic mutations in 123 unrelated Chinese patients with Marfan syndrome or a related disease.

TGFBR1 FBN1

1.23e-05371231098894
Pubmed

Recombinant von Willebrand factor-insight into structure and function through infusion studies in animals with severe von Willebrand disease.

VWF LRP1

1.23e-05371211992244
Pubmed

Clinically relevant variants in a large cohort of Indian patients with Marfan syndrome and related disorders identified by next-generation sequencing.

TGFBR1 FBN1

1.23e-05371233436942
Pubmed

LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.

FBN1 LTBP1

1.23e-05371217293099
Pubmed

Inhibition of USP4 attenuates pathological scarring by downregulation of the TGF‑β/Smad signaling pathway.

TGFBR1 USP4

1.23e-05371231173246
Pubmed

Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.

TLE1 TLE3

1.23e-05371230045946
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 LTBP1

2.46e-05471212429738
Pubmed

The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.

LRRC4C LRRC4

2.46e-05471214595443
Pubmed

The spectrum of FBN1, TGFβR1, TGFβR2 and ACTA2 variants in 594 individuals with suspected Marfan Syndrome, Loeys-Dietz Syndrome or Thoracic Aortic Aneurysms and Dissections (TAAD).

TGFBR1 FBN1

2.46e-05471224793577
Pubmed

TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.

TLE1 TLE3

2.46e-0547128645603
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN3

2.46e-05471225034023
Pubmed

Structural basis for cell surface patterning through NetrinG-NGL interactions.

LRRC4C LRRC4

2.46e-05471221946559
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

TGFBR1 FBN1

2.46e-05471216835936
Pubmed

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation.

TLE1 TLE3

2.46e-05471220108349
Pubmed

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.

LRP1 NOTCH2

2.46e-05471238462037
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLB NOTCH2

2.46e-05471232330268
Pubmed

Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube.

TLE1 TLE3

2.46e-05471211290324
Pubmed

Netrin-G/NGL complexes encode functional synaptic diversification.

LRRC4C LRRC4

2.46e-05471225411505
Pubmed

Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments.

LRRC4C LRRC4

2.46e-05471217785411
Pubmed

Corepressors TLE1 and TLE3 interact with HESX1 and PROP1.

TLE1 TLE3

2.46e-05471220181723
Pubmed

A role for cell cycle-regulated phosphorylation in Groucho-mediated transcriptional repression.

TLE1 TLE3

2.46e-05471212397081
Pubmed

Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.

NSD2 NSD1

2.46e-05471234271259
Pubmed

Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish.

TLE1 TLE3

2.46e-05471221666599
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

TLE1 TLE3 NSD1 ADNP

2.59e-058371428794006
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

FBN1 CRIM1 LRP1 ZEB2 NOTCH2

3.85e-0518471532908313
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLB NOTCH2

4.09e-05571229856954
Pubmed

Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD).

TGFBR1 FBN1

4.09e-05571219639654
Pubmed

The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription.

TLE1 TLE3

4.09e-05571211238932
Pubmed

In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.

NSD2 NSD1

4.09e-05571225494638
Pubmed

Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.

TLE1 TLE3

4.09e-0557128989517
Pubmed

Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.

NSD2 NSD1

4.09e-05571239390582
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 LTBP1

4.09e-05571234411563
Pubmed

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation.

NSD2 NSD1

4.09e-05571233135541
Pubmed

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.

TLE1 TLE3

4.09e-0557128365415
Pubmed

Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta.

TLE1 TLE3

4.09e-05571210748198
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5A NSD1 KDM1B

4.26e-053371326864203
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SALL2 KDM5A TLE1 TLE3 LRP1 KDM1B ADNP ZEB2 NOTCH2

6.10e-0585771925609649
Pubmed

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development.

TLE1 TLE3

6.13e-0567128892234
Pubmed

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

FBN1 LTBP1

6.13e-05671219349279
Pubmed

Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.

NSD2 NSD1

6.13e-05671224019522
Pubmed

Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.

TLE1 TLE3

6.13e-0567128573724
Pubmed

LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation.

TGFBR1 LRP1

6.13e-05671231023188
Pubmed

BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein.

FBN1 LTBP1

6.13e-05671217015622
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

NSD2 NSD1 ATP2A2 ZEB2

7.55e-0510971433554859
Pubmed

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

TLE1 TLE3

8.57e-05771224024827
Pubmed

Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.

TGFBR1 LTBP1

8.57e-05771219998449
Pubmed

Serum response factor is required for sprouting angiogenesis and vascular integrity.

TGFBR1 VEZF1 ITGA1

9.49e-054371318804439
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

ZNF800 GTF2H3 NSD2 NSD1 LTBP1 KDM1B ADNP

1.09e-0453371730554943
Pubmed

A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development.

TLE1 TLE3

1.14e-04871210512199
Pubmed

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor.

TGFBR1 USP4

1.14e-04871222706160
Pubmed

Six3 and Six6 activity is modulated by members of the groucho family.

TLE1 TLE3

1.14e-04871212441302
Pubmed

The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.

TLE1 TLE3

1.14e-04871216002402
Pubmed

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.

TGFBR1 ACVR1C

1.14e-04871216845371
Pubmed

Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.

TLE1 TLE3

1.14e-04871220735826
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

TLE1 TLE3

1.14e-04871228296634
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM5A NSD1 SUV39H2

1.40e-044971334368113
Pubmed

Human transcription factor protein interaction networks.

FBN1 SALL2 VEZF1 KDM5A TLE1 TLE3 ZNF516 KDM1B ADNP ATP2A2 ZEB2

1.44e-041429711135140242
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 VWF

1.47e-04971212122015
Pubmed

Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway.

TGFBR1 ACVR1C

1.47e-04971214729481
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 LTBP1

1.47e-04971238844137
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TGFBR1 TRAF7 FBN1 CRIM1 LRP1 LTBP1 ITGA1 SUCO ATP2A2 NOTCH2

1.58e-041201711035696571
Pubmed

Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.

TLE1 TLE3

1.83e-041071230571765
Pubmed

Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions.

TLE1 TLE3

1.83e-041071224487024
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM5A NSD1 SUV39H2

2.20e-045771318022353
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

VWF ATP2A2

2.23e-041171210926765
Pubmed

NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation.

LRRC4C LRRC4

2.68e-041271216980967
Pubmed

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

LMX1A NOTCH2

2.68e-041271232147304
Pubmed

Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

TGFBR1 ACVR1C

2.68e-041271223342175
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TLE1 TLE3

2.68e-041271211266540
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

VWF NOTCH2

3.16e-041371220558824
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5A KDM1B

3.16e-041371224619213
Pubmed

PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells.

ZEB2 NOTCH2

3.16e-041371227351100
Cytoband1q24

NME7 SUCO

4.40e-04207121q24
Cytoband5q35

SLIT3 NSD1

5.84e-04237125q35
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD2 NSD1 SUV39H2

1.49e-0434553487
GeneFamilyRing finger proteins

RFPL4B TRAF7 RNF168 TRIM31 TRIM22 MUL1

1.82e-0427555658
GeneFamilyType 1 receptor serine/threonine kinases

TGFBR1 ACVR1C

1.89e-047552345
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP ZEB2

9.30e-0415552529
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF17 ZNF800 SALL2 VEZF1 ZNF516 ZNF205 ZNF501 ZEB2

1.39e-0371855828
GeneFamilyPWWP domain containing

NSD2 NSD1

2.02e-03225521147
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5A KDM1B

2.40e-0324552485
GeneFamilyPHD finger proteins

KDM5A NSD2 NSD1

2.60e-039055388
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

GTF2E1 GTF2H3

2.61e-0325552565
GeneFamilyWD repeat domain containing

TRAF7 TLE1 TLE3 DYNC2I1

8.24e-03262554362
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 VWF CRIM1 OTOGL SLIT3 TECTB LTBP1

7.95e-07191707MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 VWF CRIM1 SLIT3 TECTB LTBP1 FBN3

9.45e-07196707M3008
CoexpressionNABA_CORE_MATRISOME

FBN1 VWF CRIM1 OTOGL SLIT3 TECTB LTBP1

7.85e-06270707MM17057
CoexpressionNABA_CORE_MATRISOME

FBN1 VWF CRIM1 SLIT3 TECTB LTBP1 FBN3

8.84e-06275707M5884
CoexpressionGSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP

MCM9 NME7 SUCO ZEB2 ELOF1 C2CD5

1.55e-05199706M6527
CoexpressionIIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_DN

VEZF1 ADNP ATP2A2

4.02e-0525703M16374
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

2.62e-08194717240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

2.62e-08194717ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

2.71e-08195717d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADRA1A FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

3.23e-08200717cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SSPN FBN1 LMX1A SLIT3 LRP1 LTBP1

3.82e-071767162e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

SSPN FBN1 LMX1A SLIT3 LRP1 LTBP1

3.82e-07176716f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A FBN1 SLIT3 LRP1 LTBP1 ABLIM3

4.65e-07182716c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A FBN1 SLIT3 LRP1 LTBP1 ABLIM3

4.65e-07182716dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

4.95e-07184716e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 ADRA1A SLIT3 LTBP1 ITGA1 ZEB2

5.62e-07188716b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

5.97e-071907162306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 SLIT3 LTBP1 ITGA1 ZEB2

5.97e-0719071670c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

5.97e-071907161f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.16e-07191716a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GREM2 SSPN SLIT3 LRP1 ABLIM3 NOTCH2

6.16e-0719171614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 LRP1 LTBP1 ITGA1 ZEB2

6.16e-071917161caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.16e-07191716806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.16e-07191716107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.16e-07191716bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 LRP1 LTBP1 ITGA1 ZEB2

6.16e-071917163d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.35e-071927169093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.35e-07192716d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.35e-071927169ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.55e-07193716f1199518c3626fd29bfce65070dd21a660671213
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 SLIT3 LTBP1 ITGA1 ZEB2

6.75e-07194716ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.95e-07195716d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.95e-07195716edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.95e-071957163c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

6.95e-0719571644d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ADRA1A FBN1 CRIM1 SLIT3 LTBP1 ITGA1

6.95e-07195716aa0add081881d349099d12efca5cdee098038d4e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-07196716a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 SLIT3 LTBP1 ITGA1 ZEB2

7.16e-07196716b8759e6231e0254797d6c30930407b79440c57bb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-07196716fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-07196716802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-07196716ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-0719671630ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.16e-071967163e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 LTBP1 ATP2A2

7.16e-07196716b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 LTBP1 ATP2A2

7.16e-07196716787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-071977166d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-07197716ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-0719771637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-07197716b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-071977164cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.38e-07197716c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

FBN1 SLIT3 LRP1 LTBP1 ITGA1 ZEB2

7.60e-07198716ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

SSPN FBN1 LRP1 LTBP1 ITGA1 ZEB2

8.06e-072007169d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

SSPN FBN1 LRP1 LTBP1 ITGA1 ZEB2

8.06e-072007165ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SSPN FBN1 LRP1 LTBP1 ITGA1 ZEB2

8.06e-0720071609537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADRA1A FBN1 SLIT3 LRP1 LTBP1 ZEB2

8.06e-07200716311fab076f2ceb258e3970eb21e39344b894042a
ToppCellFibroblast|World / shred by cell class for parenchyma

SSPN FBN1 SLIT3 LRP1 LTBP1 ZEB2

8.06e-07200716dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADRA1A FBN1 SLIT3 LRP1 ITGA1 ZEB2

8.06e-0720071634f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CRIM1 OTOGL LRP1 ITGA1 ZEB2 NOTCH2

8.06e-07200716bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 TECTB ITGA1 LRRC4C LRRC4

5.93e-0616171582ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR1 FBN1 CRIM1 LTBP1 ITGA1

8.89e-061757151799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 SLIT3 LRP1 LTBP1

8.89e-06175715795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

FBN1 SLIT3 LRP1 LTBP1 ZEB2

9.14e-06176715ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 SLIT3 LTBP1 ITGA1 ZEB2

9.40e-061777154943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 SLIT3 LTBP1 ITGA1 ZEB2

9.40e-061777153f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TLE1 SLIT3 LTBP1 ITGA1 ZEB2

1.16e-0518571551dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TLE1 SLIT3 LTBP1 ITGA1 ZEB2

1.16e-05185715a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GREM2 SSPN FBN1 LMX1A SLIT3

1.19e-0518671507d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 SLIT3 LTBP1 ITGA1 ZEB2

1.23e-05187715ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 SLIT3 LTBP1 ITGA1 ZEB2

1.23e-05187715530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|normal_Lung / Location, Cell class and cell subclass

GREM2 CRIM1 SLIT3 LTBP1 ITGA1

1.26e-05188715fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

FBN1 LMX1A SLIT3 LRP1 LTBP1

1.26e-05188715706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 LMX1A SLIT3 LRP1 LTBP1

1.29e-05189715d531399749409d614adca13d181830c6e3287508
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A SLIT3 LTBP1 ITGA1 ZEB2

1.29e-05189715fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP1 ITGA1 ZEB2

1.29e-05189715c734e5693808a0333139e87bd5be2597a9252afe
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GREM2 SSPN SLIT3 LRP1 NOTCH2

1.29e-0518971545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 ZEB2

1.32e-05190715bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 ZEB2

1.32e-05190715e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 ITGA1 LRRC4C ZEB2 NOTCH2

1.32e-05190715106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 ZEB2

1.32e-05190715ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP1 ITGA1 ZEB2

1.32e-051907152e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A SLIT3 LTBP1 ITGA1 ZEB2

1.32e-051907155681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ADRA1A FBN1 SLIT3 LTBP1 ITGA1

1.32e-051907153a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP1 ITGA1 ZEB2

1.32e-05190715445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

FBN1 LRP1 ABLIM3 ZEB2 NOTCH2

1.36e-051917153379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP1 ITGA1 ZEB2

1.36e-05191715c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 ITGA1 ZEB2

1.36e-0519171539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP1 ITGA1 ZEB2

1.36e-05191715cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 SLIT3 LTBP1 ITGA1

1.36e-0519171504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TLE1 SLIT3 LTBP1 ITGA1 ZEB2

1.36e-051917157b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 ITGA1 ZEB2

1.36e-05191715ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TLE1 SLIT3 LTBP1 ITGA1 ZEB2

1.36e-05191715cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 SLIT3 LTBP1 ITGA1 ZEB2

1.39e-051927154022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 ITGA1 ZEB2

1.39e-05192715bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 ITGA1 ZEB2

1.39e-051927155105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A SLIT3 LTBP1 ITGA1 ZEB2

1.39e-0519271524e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 SLIT3 LRP1 ABLIM3 ZEB2

1.39e-0519271525492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

FBN1 SLIT3 LRP1 LTBP1 ZEB2

1.39e-051927157a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADRA1A FBN1 SLIT3 LRP1 LTBP1

1.39e-05192715df1545670370fb1010c567cd059c2783eab315f7
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA1A FBN1 SLIT3 LTBP1 ITGA1

1.39e-0519271599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 SLIT3 LRP1 ABLIM3 ZEB2

1.39e-05192715de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREM2 FBN1 LTBP1 ITGA1 ZEB2

1.39e-051927159333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LRP1 ITGA1 ZEB2

1.39e-051927150ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SLIT3 LTBP1 ITGA1 ZEB2

1.43e-05193715c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREM2 FBN1 SLIT3 LRP1 LTBP1

1.43e-05193715d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADRA1A FBN1 SLIT3 LRP1 ABLIM3

1.43e-05193715fb28717fadd06c3840636d25409ce80c9254bd34
ComputationalGenes in the cancer module 123.

ADRA1A KDM5A NSD2 TLE1 TLE3 ZNF516 ZEB2

3.58e-05247417MODULE_123
DrugEnalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A

GTF2E1 SALL2 CRIM1 KDM5A TLE1 ZNF205 ABLIM3

2.31e-061986977428_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

NSD2 TLE3 ZNF516 DYNC2I1 ZNF205 LTBP1 MUL1

2.39e-061996977433_DN
DrugMoxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A

SSPN CRIM1 TLE1 ZNF516 ABLIM3 TFF2

2.96e-051976967343_UP
DrugCarcinine [56897-53-1]; Down 200; 22uM; HL60; HT_HG-U133A

CRIM1 NSD2 TLE1 NSD1 ANKMY1 NOTCH2

3.14e-051996961305_DN
DrugLoperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

TGFBR1 SSPN ANKMY1 ABLIM3 ATP2A2 TFF2

3.22e-052006965632_DN
DrugDiloxanide furoate [3736-81-0]; Down 200; 12.2uM; HL60; HT_HG-U133A

SSPN CRIM1 DNAH17 MIOS MUL1 NOTCH2

3.22e-052006963062_DN
DrugTAAD

TGFBR1 FBN1 ACVR1C

3.41e-0521693CID000133445
DiseaseSotos syndrome 1 (implicated_via_orthology)

NSD2 NSD1

1.57e-053682DOID:0112103 (implicated_via_orthology)
DiseaseFamilial aortopathy

TGFBR1 FBN1

1.57e-053682cv:CN078214
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN3

1.57e-053682DOID:65 (implicated_via_orthology)
Diseasespontaneous coronary artery dissection

FBN1 LRP1 ITGA1

5.02e-0531683EFO_0010820
DiseaseFEV/FEC ratio

GREM2 FBN1 CRIM1 ZNF516 LRP1 NSD1 DEFB136 LTBP1 ITGA1 ACVR1C ZEB2

1.08e-0412286811EFO_0004713
Diseasecognitive impairment measurement

GREM2 SSPN FBN3

1.45e-0444683EFO_0007998
Diseasemesangial proliferative glomerulonephritis (biomarker_via_orthology)

FBN1 VWF

1.45e-048682DOID:4783 (biomarker_via_orthology)
DiseaseBMI-adjusted waist circumference, physical activity measurement

SSPN TLE3 NSD1 LTBP1

1.91e-04123684EFO_0007789, EFO_0008002
Diseaseaortic aneurysm

FBN1 LRP1

2.33e-0410682EFO_0001666
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

TGFBR1 FBN1

2.33e-0410682cv:C4707243
Diseasepulse pressure measurement

TRAF7 FBN1 CRIM1 KDM5A ZNF516 SLIT3 LRP1 DEFB136 LTBP1 ITGA1 NME7

3.19e-0413926811EFO_0005763
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

SLIT3 LRP1

3.40e-0412682DOID:3827 (implicated_via_orthology)
DiseaseParoxysmal atrial fibrillation

SSPN VWF SLIT3 KDM1B

4.71e-04156684C0235480
Diseasefamilial atrial fibrillation

SSPN VWF SLIT3 KDM1B

4.71e-04156684C3468561
DiseasePersistent atrial fibrillation

SSPN VWF SLIT3 KDM1B

4.71e-04156684C2585653
Diseaselymphocyte count

ZNF800 SSPN FBN1 DNAH17 TRIM31 NSD1 SAE1 USP4 ITGA1 ELOF1 NOTCH2

4.89e-0414646811EFO_0004587
DiseaseAtrial Fibrillation

SSPN VWF SLIT3 KDM1B

5.18e-04160684C0004238
DiseaseMalignant neoplasm of breast

ADRA1A VWF OTOGL NSD2 TLE3 ADGRF4 SUV39H2 ZEB2 NOTCH2

7.77e-041074689C0006142
Diseasesyndrome (implicated_via_orthology)

NSD2 NSD1

7.82e-0418682DOID:225 (implicated_via_orthology)
DiseaseAbnormality of refraction

TDRD7 TGFBR1 FBN1 KDM5A ZNF516 LRRC4C FBN3

9.04e-04673687HP_0000539
Diseaseglomerulonephritis (biomarker_via_orthology)

FBN1 LTBP1

9.68e-0420682DOID:2921 (biomarker_via_orthology)
Diseaserefractive error, age at onset, Myopia

TGFBR1 FBN1 LRRC4C ZEB2

1.04e-03193684EFO_0004847, HP_0000545, MONDO_0004892
Diseasebeta-aminoisobutyric acid measurement

KDM5A FBN3

1.40e-0324682EFO_0010464
Diseasemigraine disorder

FECH LRP1 NSD1 SUV39H2 ZEB2

1.41e-03357685MONDO_0005277
Diseaseatrial fibrillation

SSPN LMX1A TLE3 SLIT3 KDM1B

1.67e-03371685EFO_0000275
DiseaseLiver Cirrhosis

TGFBR1 ADRA1A FBN1

1.76e-03103683C0023890
DiseaseFibrosis, Liver

TGFBR1 ADRA1A FBN1

1.86e-03105683C0239946
Diseasepulmonary hypertension (is_implicated_in)

VWF ATP2A2

2.18e-0330682DOID:6432 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
TKPFCCSACPFSSKF

ADNP

71

Q9H2P0
TSECFSTTACPVAFI

nan

16

P0DMU3
VTFSGKECVCQTCSQ

ABLIM3

121

O94929
IDICFPSNICVSVCF

BRICD5

241

Q6PL45
TAFTTCCTLSEEFAC

AFM

456

P43652
SKSFLQVCCCVGPST

ADRA1A

426

P35348
CISSSNCSQPCAKDF

ADGRF4

56

Q8IZF3
VTKTECCFTDFCNNI

ACVR1C

81

Q8NER5
CSVPKAFNTTKTRCC

FBN3

2026

Q75N90
ETQFTCPFCNHEKSC

ELOF1

21

P60002
AASFCEMCPSSFCKQ

NSD1

2171

Q96L73
GSTCTTVANQFSCKC

NOTCH2NLB

156

P0DPK3
GSTCTTVANQFSCKC

NOTCH2

156

Q04721
TCSPKQFACRDQITC

LRP1

26

Q07954
ESQVTCCCLSPLKAF

DYNC2I1

696

Q8WVS4
QCASCKEPLETTCFY

LMX1A

61

Q8TE12
FTPSICKVTCTKGSC

LTBP1

356

Q14766
KVSQCRCFMFCFIPS

FAM221B

291

A6H8Z2
PSTSFCHLCPNSFCK

NSD2

1291

O96028
ACVVCLSSFKSCVFL

MUL1

301

Q969V5
CPSVCSCSNQFSKVV

LRRC4

46

Q9HBW1
TCPSVCSCSNQFSKV

LRRC4C

46

Q9HCJ2
CPVCLDFFSCSISLS

RFPL4B

11

Q6ZWI9
DCNTCKFATITCNLT

ITGA1

1061

P56199
SFQSCAFCKPQRVTS

GREM2

116

Q9H772
TTCFLSALTCSCNPE

KDM5A

681

P29375
ECVQPATKSCSFSAC

ATP2A2

996

P16615
TCPVCFASASERCAK

KDM1B

61

Q8NB78
TIFCQGFDDCSCIKS

DNAH17

506

Q9UFH2
KCINTFGSFQCRCPT

FBN1

1621

P35555
ICIDSVISCFSESCP

CRIM1

776

Q9NZV1
VISCFSESCPSVSCE

CRIM1

781

Q9NZV1
LCSAETKFESNVCVC

ANKMY1

461

Q9P2S6
SFCSPGKLNSVCISC

LYPD1

86

Q8N2G4
SCQPSCESSFCKATL

KRTAP29-1

326

A8MX34
CVNPVCRETKSFFTS

FECH

406

P22830
RTCTSQKAVCFFGCP

DEFB136

31

Q30KP8
SCKFVQNPGISCCES

RNASE11

136

Q8TAA1
CAKCCAQFTDPTEFL

SALL2

36

Q9Y467
SCGVKFFCTTSIPKC

C2CD5

141

Q86YS7
FTNCTCCIVKPHAVS

NME7

236

Q9Y5B8
CFSPFCVCESCTKPV

OTOGL

2001

Q3ZCN5
SCPSLESCDSSKFTC

MCM9

171

Q9NXL9
SFKCPVCSSTFTDLE

GTF2E1

126

P29083
TSCGFFKCPLCKTSV

TRIM31

46

Q9BZY9
KEVCSTCVQDFSNCS

POLR1A

61

O95602
SFFTQFDAVCLTCCS

SAE1

121

Q9UBE0
TQFTCETTLDSCQCK

SSPN

151

Q14714
TFICDSEKLSCPVTC

TECTB

266

Q96PL2
TSECFVSLPFCGKIC

TDRD7

696

Q8NHU6
CTKDNFTCVTDGLCF

TGFBR1

41

P36897
AVACPTKCTCSAASV

SLIT3

31

O75094
CCICGKSFPFQSSLS

ZNF516

36

Q92618
AISPDSKVCFSCCSD

TLE1

581

Q04724
CPECAKVSVTFDPFC

USP4

461

Q13107
STERPFKCQTCTAAF

VEZF1

256

Q14119
VCPSGFQLSCKTSAC

VWF

2556

P04275
SSKPLAQVFVSCNFC

MIOS

726

Q9NXC5
EATFGCSCTDCFFQK

SUV39H2

186

Q9H5I1
ISPEECASRKCCFSN

TFF2

96

Q03403
CQLCCSVFKDPVITT

TRAF7

131

Q6Q0C0
FCSELTTICCISSFS

SUCO

616

Q9UBS9
CKPCFQSTVEKASLC

RNF168

36

Q8IYW5
QSTVEKASLCCPFCR

RNF168

41

Q8IYW5
ALAISPDAKVCFSCC

TLE3

581

Q04726
NSFCSRCCSFKVPKS

ZFYVE27

371

Q5T4F4
KCPICAKCFTQSSAL

ZNF205

421

O95201
SRSCPVCCKSFATKA

ZNF800

286

Q2TB10
NISTPFSCQFCKESF

ZEB2

576

O60315
PCANTTFCCKFASFP

PVRIG

126

Q6DKI7
VRTCTFKNSNPCDFS

TRIM22

326

Q8IYM9
CLSIFCNFSPICTTC

GTF2H3

271

Q13889
CNFSPICTTCETAFK

GTF2H3

276

Q13889
ECSECGKFFVDSCTL

ZNF17

471

P17021
CTECGKAFSQSICLT

ZNF501

136

Q96CX3