Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	1.48e-06	5	107	3	GO:0030156
GeneOntologyBiologicalProcess	vascular associated smooth muscle cell development	EFEMP2 NOTCH1 SMAD6	5.74e-05	15	106	3	GO:0097084
GeneOntologyBiologicalProcess	aorta morphogenesis	EFEMP2 LRP1 NOTCH1 TBX1	5.76e-05	41	106	4	GO:0035909
GeneOntologyBiologicalProcess	aorta development	EFEMP2 LRP1 NOTCH1 TBX1 SMAD6	5.77e-05	80	106	5	GO:0035904
GeneOntologyBiologicalProcess	artery development	EFEMP2 ZMIZ1 LRP1 NOTCH1 TBX1 SMAD6	6.46e-05	133	106	6	GO:0060840
GeneOntologyCellularComponent	collagen type IX trimer	COL9A1 COL16A1	1.55e-04	4	107	2	GO:0005594
GeneOntologyCellularComponent	FACIT collagen trimer	COL9A1 COL16A1	3.84e-04	6	107	2	GO:0005593
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	3.89e-04	28	107	3	GO:0002177
HumanPheno	Hypoplastic left heart	PKD1L1 KMT2D NOTCH1 TBX1 SMAD6	3.42e-05	49	40	5	HP:0004383
HumanPheno	Congenital malformation of the left heart	PKD1L1 KMT2D NOTCH1 TBX1 SMAD6	4.16e-05	51	40	5	HP:0045017
HumanPheno	Hypoplastic heart	PKD1L1 KMT2D NOTCH1 TBX1 SMAD6	5.50e-05	54	40	5	HP:0001961
Domain	EGF_CA	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	4.75e-07	86	103	7	PF07645
Domain	Sushi_SCR_CCP_dom	SELE C1RL CSMD2 C2 C6 CSMD1	7.02e-07	57	103	6	IPR000436
Domain	EGF_Ca-bd_CS	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	1.08e-06	97	103	7	IPR018097
Domain	EGF-like_dom	SELE FAT4 EFEMP2 CUBN FCGBP SCUBE2 LRP1 C6 ADGRE1 NOTCH1	1.18e-06	249	103	10	IPR000742
Domain	EGF_CA	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	1.24e-06	99	103	7	PS01187
Domain	ASX_HYDROXYL	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	1.33e-06	100	103	7	PS00010
Domain	EGF-like_CS	SELE FAT4 EFEMP2 CUBN SCUBE2 LRP1 C6 ADGRE1 NOTCH1 EPHA1	1.80e-06	261	103	10	IPR013032
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	1.97e-06	106	103	7	IPR000152
Domain	EGF_2	SELE FAT4 EFEMP2 CUBN SCUBE2 LRP1 C6 ADGRE1 NOTCH1 EPHA1	2.07e-06	265	103	10	PS01186
Domain	Growth_fac_rcpt_	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1 EPHA1	2.40e-06	156	103	8	IPR009030
Domain	EGF_CA	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	5.03e-06	122	103	7	SM00179
Domain	EGF-like_Ca-bd_dom	FAT4 EFEMP2 CUBN SCUBE2 LRP1 ADGRE1 NOTCH1	5.61e-06	124	103	7	IPR001881
Domain	EGF_3	SELE FAT4 EFEMP2 CUBN SCUBE2 LRP1 C6 ADGRE1 NOTCH1	6.10e-06	235	103	9	PS50026
Domain	EGF	SELE FAT4 EFEMP2 CUBN FCGBP SCUBE2 LRP1 ADGRE1 NOTCH1	6.10e-06	235	103	9	SM00181
Domain	CUB	C1RL CUBN CSMD2 SCUBE2 CSMD1	7.27e-06	49	103	5	PF00431
Domain	CUB	C1RL CUBN CSMD2 SCUBE2 CSMD1	8.05e-06	50	103	5	SM00042
Domain	-	C1RL CUBN CSMD2 SCUBE2 CSMD1	9.79e-06	52	103	5	2.60.120.290
Domain	Sushi	SELE CSMD2 C2 C6 CSMD1	9.79e-06	52	103	5	PF00084
Domain	CUB	C1RL CUBN CSMD2 SCUBE2 CSMD1	1.08e-05	53	103	5	PS01180
Domain	EGF_1	SELE FAT4 EFEMP2 CUBN SCUBE2 LRP1 C6 ADGRE1 NOTCH1	1.18e-05	255	103	9	PS00022
Domain	CCP	SELE CSMD2 C2 C6 CSMD1	1.18e-05	54	103	5	SM00032
Domain	cEGF	EFEMP2 SCUBE2 LRP1 ADGRE1	1.19e-05	26	103	4	IPR026823
Domain	cEGF	EFEMP2 SCUBE2 LRP1 ADGRE1	1.19e-05	26	103	4	PF12662
Domain	SUSHI	SELE CSMD2 C2 C6 CSMD1	1.41e-05	56	103	5	PS50923
Domain	CUB_dom	C1RL CUBN CSMD2 SCUBE2 CSMD1	1.54e-05	57	103	5	IPR000859
Domain	LDLRA_1	LDLRAD3 LRP1 C6 ALK	1.41e-04	48	103	4	PS01209
Domain	LDLRA_2	LDLRAD3 LRP1 C6 ALK	1.53e-04	49	103	4	PS50068
Domain	LDrepeatLR_classA_rpt	LDLRAD3 LRP1 C6 ALK	1.53e-04	49	103	4	IPR002172
Domain	LDLa	LDLRAD3 LRP1 C6 ALK	1.53e-04	49	103	4	SM00192
Domain	UCH	USP53 USP29 USP42 PAN2	6.38e-04	71	103	4	PF00443
Domain	EGF	SELE CUBN SCUBE2 LRP1 NOTCH1	6.66e-04	126	103	5	PF00008
Domain	USP_3	USP53 USP29 USP42 PAN2	6.73e-04	72	103	4	PS50235
Domain	USP_dom	USP53 USP29 USP42 PAN2	6.73e-04	72	103	4	IPR028889
Domain	Peptidase_C19_UCH	USP53 USP29 USP42 PAN2	6.73e-04	72	103	4	IPR001394
Domain	LDLR_class-A_CS	LDLRAD3 LRP1 C6	1.39e-03	40	103	3	IPR023415
Domain	EGF_3	CUBN SCUBE2	1.92e-03	12	103	2	PF12947
Domain	TIL	MUC19 FCGBP	1.92e-03	12	103	2	PF01826
Domain	EGF_dom	CUBN SCUBE2	1.92e-03	12	103	2	IPR024731
Domain	C8	MUC19 FCGBP	1.92e-03	12	103	2	PF08742
Domain	Ldl_recept_a	LDLRAD3 LRP1 C6	1.95e-03	45	103	3	PF00057
Domain	-	LDLRAD3 LRP1 ALK	2.08e-03	46	103	3	4.10.400.10
Domain	Unchr_dom_Cys-rich	MUC19 FCGBP	2.26e-03	13	103	2	IPR014853
Domain	C8	MUC19 FCGBP	2.26e-03	13	103	2	SM00832
Domain	TIL_dom	MUC19 FCGBP	2.62e-03	14	103	2	IPR002919
Domain	Post-SET_dom	SETD1A KMT2D	3.44e-03	16	103	2	IPR003616
Domain	VWD	MUC19 FCGBP	3.44e-03	16	103	2	SM00216
Domain	PostSET	SETD1A KMT2D	3.44e-03	16	103	2	SM00508
Domain	VWF_type-D	MUC19 FCGBP	3.44e-03	16	103	2	IPR001846
Domain	VWFD	MUC19 FCGBP	3.44e-03	16	103	2	PS51233
Domain	POST_SET	SETD1A KMT2D	3.44e-03	16	103	2	PS50868
Domain	VWD	MUC19 FCGBP	3.44e-03	16	103	2	PF00094
Domain	Laminin_G	FAT4 COL9A1 COL16A1	4.03e-03	58	103	3	IPR001791
Domain	VWC_out	MUC19 FCGBP	4.84e-03	19	103	2	SM00215
Domain	PRAME_family	PRAMEF7 PRAMEF8	4.84e-03	19	103	2	IPR026271
Domain	FN3	AXL RIMBP3 RIMBP3C RIMBP3B EPHA1	4.92e-03	199	103	5	PS50853
Pubmed	USP51 promotes deubiquitination and stabilization of ZEB1.	USP53 USP29 USP42 PAN2	6.39e-08	13	109	4	29119051
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B ZNF541	8.92e-08	14	109	4	17662146
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.20e-07	4	109	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	2.98e-07	5	109	3	17855024
Pubmed	Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2).	ABCG2 ALK	9.73e-06	2	109	2	26361725
Pubmed	ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT.	AXL ALK	9.73e-06	2	109	2	26616860
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD2 CSMD1	9.73e-06	2	109	2	24408017
Pubmed	Developing multidrug-resistant cells and exploring correlation between BCRP/ABCG2 over-expression and DNA methyltransferase.	ABCG2 DNMT3B	9.73e-06	2	109	2	21106767
Pubmed	Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes.	CBFA2T3 FBXO31	9.73e-06	2	109	2	12213200
Pubmed	Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification.	CBFA2T3 NOTCH1	9.73e-06	2	109	2	20123979
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD2 CSMD1	9.73e-06	2	109	2	27890662
Pubmed	The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.	CSMD2 CSMD1	9.73e-06	2	109	2	21439553
Pubmed	Verifying AXL and putative proteins as SARS-CoV-2 receptors by DnaE intein-based rapid cell-cell fusion assay.	AXL LDLRAD3	9.73e-06	2	109	2	37461287
Pubmed	TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.	TET2 CSMD1	9.73e-06	2	109	2	25695618
Pubmed	FBXO31 sensitizes cancer stem cells-like cells to cisplatin by promoting ferroptosis and facilitating proteasomal degradation of GPX4 in cholangiocarcinoma.	GPX4 FBXO31	9.73e-06	2	109	2	36269678
Pubmed	Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.	TET2 KMT2D	9.73e-06	2	109	2	31311407
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD1	2.91e-05	3	109	2	12906867
Pubmed	Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.	ZMIZ1 NOTCH1	2.91e-05	3	109	2	23161489
Pubmed	Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.	KMT2D NOTCH1	2.91e-05	3	109	2	27566587
Pubmed	LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.	LDLRAD3 LRP1	2.91e-05	3	109	2	21795536
Pubmed	Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes.	TET2 DNMT3B	2.91e-05	3	109	2	32957806
Pubmed	Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct.	TET2 DNMT3B	2.91e-05	3	109	2	23926181
Pubmed	PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation.	TET2 DNMT3B	2.91e-05	3	109	2	24028770
Pubmed	Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development.	ZMIZ1 NOTCH1	2.91e-05	3	109	2	30076146
Pubmed	Reduction in DNA methyltransferases and alteration of DNA methylation pattern associate with mouse skin ageing.	TET2 DNMT3B	2.91e-05	3	109	2	24645644
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	TET2 KMT2D	2.91e-05	3	109	2	26551667
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP53 USP42 PAN2	5.07e-05	23	109	3	14715245
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 ZCCHC8 TNRC6B ICE1 ZMIZ1 KMT2D ALMS1 LRP1	5.37e-05	418	109	8	34709266
Pubmed	HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.	MCM2 NOTCH1 TBX1	5.78e-05	24	109	3	21149574
Pubmed	[DNA hypomethylation in villi of patients with unexplained recurrent spontaneous abortion and its mechanism].	TET2 DNMT3B	5.82e-05	4	109	2	31167695
Pubmed	Identification of novel argonaute-associated proteins.	TNRC6B MOV10	5.82e-05	4	109	2	16289642
Pubmed	Motoneuronal death during spinal cord development is mediated by oxidative stress.	GPX4 SOD2	5.82e-05	4	109	2	15637642
Pubmed	DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development.	TET2 DNMT3B	5.82e-05	4	109	2	30850438
Pubmed	FLT3-ITD and MLL-PTD influence the expression of MDR-1, MRP-1, and BCRP mRNA but not LRP mRNA assessed with RQ-PCR method in adult acute myeloid leukemia.	LRP1 ABCG2	5.82e-05	4	109	2	24030729
Pubmed	Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease.	NOTCH1 SMAD6	5.82e-05	4	109	2	32748548
Pubmed	MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases.	SETD1A DNMT3B	5.82e-05	4	109	2	28106784
Pubmed	ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression.	ZNF423 NOTCH1	5.82e-05	4	109	2	20547764
Pubmed	Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner.	SELE LRP1	5.82e-05	4	109	2	15591119
Pubmed	MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.	TNRC6B MOV10	5.82e-05	4	109	2	24726324
Pubmed	Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.	USP53 FBXO31	5.82e-05	4	109	2	33664230
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	SETD1A ELP1 MCM2 KMT2D	6.75e-05	69	109	4	28481362
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	SELE ABCA4 CAPN10 LRP1 C2 SOD2	8.78e-05	229	109	6	19948975
Pubmed	Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.	COL9A1 DCT TBX1	9.27e-05	28	109	3	20346939
Pubmed	Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.	TET2 ADGRE1	9.67e-05	5	109	2	29108636
Pubmed	Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.	CAPN10 LRP1 C2 SOD2	9.84e-05	76	109	4	19336475
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	TET2 LRP1 ASB1	1.14e-04	30	109	3	21946350
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETD1A ZCCHC8 MCM2 KMT2D ALMS1 USP42 CRYBG1 MOV10	1.19e-04	469	109	8	27634302
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP29 C1RL USP42 PAN2	1.26e-04	81	109	4	12838346
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C1RL C2 C6	1.26e-04	31	109	3	19344414
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	CPNE8 FAT4 AXL EFEMP2 C1RL CUBN FCGBP GUSB C2 UPK3A C6 SOD2	1.37e-04	1070	109	12	23533145
Pubmed	Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer.	GPX4 SOD2	1.45e-04	6	109	2	21052528
Pubmed	Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.	ABCA4 ABCG2	1.45e-04	6	109	2	12111378
Pubmed	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	SETD1A KMT2D	1.45e-04	6	109	2	34933446
Pubmed	An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.	AXL LRP1	1.45e-04	6	109	2	24509082
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	TPCN2 ZNF423 FCGBP CSMD1	1.45e-04	84	109	4	15203218
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP53 USP29 PAN2	1.53e-04	33	109	3	30323974
Pubmed	Neural crest cell lineage segregation in the mouse neural tube.	DCT ADGRE1	2.02e-04	7	109	2	15548576
Pubmed	Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.	AXL ALK	2.02e-04	7	109	2	19815557
Pubmed	Notch pathway activation targets AML-initiating cell homeostasis and differentiation.	TET2 NOTCH1	2.02e-04	7	109	2	23359070
Pubmed	Expression and regulation of antioxidant enzymes in the developing limb support a function of ROS in interdigital cell death.	GPX4 SOD2	2.69e-04	8	109	2	16445905
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1A KMT2D	2.69e-04	8	109	2	22266653
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A KMT2D	2.69e-04	8	109	2	23130995
Pubmed	DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.	TET2 DNMT3B	2.69e-04	8	109	2	28614801
Pubmed	Single-nucleotide polymorphisms within the antioxidant defence system and associations with aggressive prostate cancer.	GPX4 SOD2	2.69e-04	8	109	2	20477822
Pubmed	Genetic variants in selenoprotein genes increase risk of colorectal cancer.	GPX4 SOD2	2.69e-04	8	109	2	20378690
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 TET2 SETD1A MCM2 ICE1 CAPN10 PAN2 SENP6	2.69e-04	529	109	8	14621295
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TNRC6B KMT2D ALMS1 LRP1 NOTCH1	2.94e-04	184	109	5	32908313
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1A KMT2D	3.45e-04	9	109	2	22665483
Pubmed	Noncanonical Notch signals have opposing roles during cardiac development.	NOTCH1 TBX1	3.45e-04	9	109	2	34487959
Pubmed	Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer.	GPX4 SOD2	3.45e-04	9	109	2	17634480
Pubmed	Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.	SETD1A KMT2D	3.45e-04	9	109	2	26691508
Pubmed	Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.	KMT2D TBX1	3.45e-04	9	109	2	35296311
Pubmed	Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a.	SETD1A MCM2	3.45e-04	9	109	2	38971831
Pubmed	Identification of the ligands of protein interaction domains through a functional approach.	CUBN LRP1	3.45e-04	9	109	2	17124247
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	GPX4 CUBN SLC5A2 ERMN MMP24 FCGBP GUSB N4BP2L2 UPK3A MBD5 ALK	3.55e-04	1016	109	11	19056867
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	USP53 TET2 TNRC6B FBXO31 NOTCH1 AGAP3	4.26e-04	307	109	6	37499664
Pubmed	Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer.	GPX4 SOD2	4.31e-04	10	109	2	16424062
Pubmed	Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5.	ADGRE1 NOTCH1	4.31e-04	10	109	2	37669937
Pubmed	Interactions between genes involved in the antioxidant defence system and breast cancer risk.	GPX4 SOD2	4.31e-04	10	109	2	16868544
Pubmed	Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.	C2 SOD2	4.31e-04	10	109	2	22705344
Pubmed	Polymorphisms in innate immunity genes and risk of childhood leukemia.	SELE C1RL C2 C6 SOD2	4.93e-04	206	109	5	20438785
Pubmed	Risk of meningioma and common variation in genes related to innate immunity.	SELE C1RL C2 C6 SOD2	5.03e-04	207	109	5	20406964
Pubmed	Common variation in genes related to innate immunity and risk of adult glioma.	SELE C1RL C2 C6 SOD2	5.15e-04	208	109	5	19423540
Pubmed	Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.	GPX4 STS SOD2 DNMT3B	5.15e-04	117	109	4	19124506
Pubmed	Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches.	DCT NOTCH1	5.26e-04	11	109	2	22510689
Pubmed	Single-cell transcriptional analysis reveals developmental stage-dependent changes in retinal progenitors in the murine early optic vesicle.	COL9A1 DCT	5.26e-04	11	109	2	33548738
Pubmed	Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.	CSMD2 ZSCAN20	5.26e-04	11	109	2	16429158
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	FAT4 CBFA2T3	5.26e-04	11	109	2	24349473
Pubmed	Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.	SETD1A KMT2D	5.26e-04	11	109	2	18082152
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	SETD1A KMT2D UTY	5.27e-04	50	109	3	37974198
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	CCDC134 PRAMEF7 SETD1A ABCA4 TMEM241 TMC6 ELP1 PRAMEF8 SLC5A2 USP42 ENTPD1 CSMD1	5.28e-04	1242	109	12	30973865
Pubmed	Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.	FBXO31 NOTCH1	6.29e-04	12	109	2	24085301
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	SETD1A KMT2D	6.29e-04	12	109	2	27563068
Pubmed	Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease.	UPK3A ADGRE1	6.29e-04	12	109	2	31808745
Pubmed	Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity.	DCT NOTCH1	7.42e-04	13	109	2	15576400
Pubmed	Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.	UPK3A NOTCH1	7.42e-04	13	109	2	23132245
Pubmed	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	GPX4 MUC19 PUSL1 ZMIZ1 RIMBP3 DNMT3B	7.49e-04	342	109	6	23128233
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TET2 ZMIZ1 ALMS1 MBD5	7.66e-04	130	109	4	12421765
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 SETD1A ZNF423 ZMIZ1 KMT2D ALMS1	8.57e-04	351	109	6	38297188
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	ABCA4 GPX4 ELP1 ALMS1 SOD2	8.58e-04	233	109	5	32290105
Cytoband	22q11.21	RIMBP3 RIMBP3C RIMBP3B TBX1	1.48e-04	111	109	4	22q11.21
Cytoband	1p34.3	CSMD2 ZSCAN20 C1orf216	4.45e-04	62	109	3	1p34.3
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELE C1RL CSMD2 C2 C6 CSMD1	1.38e-07	57	76	6	1179
GeneFamily	Ubiquitin specific peptidases	USP53 USP29 USP42 PAN2	8.97e-05	56	76	4	366
ToppCell	COPD-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	USP53 PHLDB3 TET2 AXL ENTPD1 LAMP3 CRYBG1 CSMD1	2.50e-08	192	109	8	984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCell	Control-Myeloid-cDC2\|Control / Disease state, Lineage and Cell class	PHLDB3 TET2 HTR7 AXL ENTPD1 CRYBG1 CSMD1	4.44e-07	190	109	7	4e481e42353d47af7991744000403af2873f6a41
ToppCell	Control-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	PHLDB3 TET2 HTR7 AXL ENTPD1 LAMP3 CSMD1	4.60e-07	191	109	7	11dfd8f38beb294f42710cfbd355cb089e1023c0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 EPHA1	1.58e-06	80	109	5	0d02b242164d27f38f70ed77b106612fc7a3abca
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 EPHA1	1.58e-06	80	109	5	313344cf7309bc17ca131b92a91b24489df577e2
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Tmem2_(Tmem2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 EPHA1	1.58e-06	80	109	5	b95e4456adb7f7d42825351f010376c10bb35380
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 FCGBP	4.32e-06	98	109	5	7a62a77ca83153dacff4d02d6e32104227d0980d
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)\|Striatum / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 FCGBP	4.32e-06	98	109	5	26250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT SLC5A2 FCGBP	4.32e-06	98	109	5	42875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AXL TMC6 LRP1 C2 GSG1L ADGRE1	5.09e-06	178	109	6	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 SLC34A3 DCT FCGBP	5.51e-06	103	109	5	287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCell	Severe-Myeloid-mDC\|Severe / Condition, Lineage, Cell class and cell subclass	HTR7 AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	5.60e-06	181	109	6	00f2949b609ac21bd2da6fd8f685739eeb2f48ad
ToppCell	Severe-Myeloid-mDC-\|Severe / Condition, Lineage, Cell class and cell subclass	HTR7 AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	5.60e-06	181	109	6	51ded98c76ec35ab1d24ac3ab98280381daa9831
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 VSIG1 SLC34A3 DCT	5.78e-06	104	109	5	30b2f6f6612ea45c92f0d466e301d85291a2ee70
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 VSIG1 SLC34A3 DCT	5.78e-06	104	109	5	a0e03cc97d453050c6b7e6e290ef0babc7bc1276
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 VSIG1 SLC34A3 DCT	5.78e-06	104	109	5	3cc15f0abdf1f4304af9152911a1f3aab3bc0925
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HTR7 CBFA2T3 LDLRAD3 SCUBE2 ENTPD1 LAMP3	6.16e-06	184	109	6	4f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCell	COPD-Myeloid-cDC2\|COPD / Disease state, Lineage and Cell class	PHLDB3 TET2 AXL ENTPD1 CRYBG1 CSMD1	7.62e-06	191	109	6	2af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCell	COPD-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	PHLDB3 TET2 AXL ENTPD1 CRYBG1 CSMD1	7.62e-06	191	109	6	4e4887175200a57e1b041f2f131e3df774df3509
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPNE8 FAT4 COL9A1 ENTPD1 CSMD1 SMAD6	7.62e-06	191	109	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	IPF-Myeloid-cDC2\|IPF / Disease state, Lineage and Cell class	TET2 AXL ENTPD1 LAMP3 CRYBG1 UPK3A	7.85e-06	192	109	6	fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCell	Control-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	PHLDB3 AXL ENTPD1 LAMP3 CRYBG1 CSMD1	8.09e-06	193	109	6	4cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCell	IPF-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	USP53 PHLDB3 AXL ENTPD1 LAMP3 CRYBG1	8.33e-06	194	109	6	accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	C1RL DCT INPP4B SCUBE2 TBX1	9.45e-06	115	109	5	f3062a7247b376e9978dc01109fb94d6dd960052
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL9A1 COL16A1 SCUBE2 FBXO31 WSCD2 GYG2	9.91e-06	200	109	6	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL9A1 COL16A1 SCUBE2 FBXO31 WSCD2 GYG2	9.91e-06	200	109	6	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MCM2 ENTPD1 CRYBG1 N4BP2L2 ZNF292	2.05e-05	135	109	5	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT FCGBP	2.79e-05	71	109	4	2220e1b02baa71961cfc85536bafeb313e588bf3
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT FCGBP	2.79e-05	71	109	4	cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCell	MS-CD4-CD8_2\|MS / Condition, Cell_class and T cell subcluster	TPCN2 VSIG2 LAMP3 ADGRE1 ZNF541	3.30e-05	149	109	5	08fb6be5599c5988890c851ce5ac6781c319948e
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELP1 CBFA2T3 ERMN DDIAS GORAB	3.63e-05	152	109	5	dd728aa3ffdb2c415730a62678f69cf0e8af09df
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT EPHA1	4.26e-05	79	109	4	cd182dbc8d0ccc2406e78c9ba71476c1f463359b
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL9A1 PKD1L1 DCT EPHA1	4.26e-05	79	109	4	bcb9181d7de7a385b890523299f8290836aa536e
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	TNRC6B INPP4B CRYBG1 N4BP2L2 UTY	4.91e-05	162	109	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE8 CBFA2T3 ENTPD1 PAN2 ABCG2	6.01e-05	169	109	5	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL ENTPD1 LRP1 C6 ADGRE1	6.01e-05	169	109	5	44d841fd997a6f26104f16cd00223ecce8352f43
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL ENTPD1 LRP1 C6 ADGRE1	6.01e-05	169	109	5	0f5e737b265ba333275a0cd289dab029a1542075
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE8 CBFA2T3 ENTPD1 PAN2 ABCG2	6.01e-05	169	109	5	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL ENTPD1 LRP1 C6 ADGRE1	6.01e-05	169	109	5	aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TET2 TMC6 IKZF4 UPK3A TBX1	6.53e-05	172	109	5	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ELP1 INPP4B KMT2D CES4A ASB1	7.28e-05	176	109	5	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	AXL GPX4 FCGBP LAMP3 C2	7.47e-05	177	109	5	945b2d0723a0a35c767604ae607d2c2d53bf0c82
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 ASB14 MMP24 GPR75 ZNF541	7.88e-05	179	109	5	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SELE LDLRAD3 ENTPD1 ABCG2 SOD2	7.88e-05	179	109	5	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	mild_COVID-19_(asymptomatic)-cDC\|World / disease group, cell group and cell class (v2)	HTR7 AXL ZMIZ1 UPK3A SMAD6	8.09e-05	180	109	5	68d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 ZNF423 ENTPD1 ABCG2 SMAD6	8.09e-05	180	109	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL ENTPD1 LRP1 C6 ADGRE1	8.30e-05	181	109	5	a93df1ba23d5b5f249491d69d12bfc0e274dafcf
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	TNRC6B INPP4B CRYBG1 N4BP2L2 UTY	8.30e-05	181	109	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	NRDC ICE1 INPP4B LAMP3 ADGRE1	8.52e-05	182	109	5	877b6e611626628e709568747512f2827ebb2795
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPNE8 INPP4B CRYBG1 ABCG2 DNMT3B	8.52e-05	182	109	5	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELE ABCA4 ZNF423 NEU3 SMAD6	8.75e-05	183	109	5	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	USP53 ANKRD31 AXL CBFA2T3 ENTPD1	8.97e-05	184	109	5	1c56378b3888c46258d446b47de4d6282fe74b0d
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	USP53 ANKRD31 AXL CBFA2T3 ENTPD1	8.97e-05	184	109	5	a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1RL CSMD2 GPR75 LRP1 SOD2	9.20e-05	185	109	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	AXL MUC19 ZMIZ1 CBFA2T3 UPK3A	9.68e-05	187	109	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SELE FAT4 ZNF423 ENTPD1 SMAD6	9.68e-05	187	109	5	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TNRC6B MCM2 CRYBG1 N4BP2L2 ZNF292	1.02e-04	189	109	5	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CPNE8 FAT4 ZNF423 ENTPD1 SMAD6	1.04e-04	190	109	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPNE8 COL9A1 ENTPD1 CSMD1 SMAD6	1.04e-04	190	109	5	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 ZNF423 CSMD1 TBX1 SMAD6	1.04e-04	190	109	5	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	AXL CBFA2T3 FCGBP ENTPD1 UPK3A	1.04e-04	190	109	5	468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell	IPF-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	TET2 AXL ENTPD1 CRYBG1 UPK3A	1.07e-04	191	109	5	9fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE8 CBFA2T3 ENTPD1 NOTCH1 SMAD6	1.07e-04	191	109	5	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE CPNE8 ZNF423 ENTPD1 C6	1.10e-04	192	109	5	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	367C-Myeloid-Dendritic\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	USP53 AXL CBFA2T3 ENTPD1 LAMP3	1.10e-04	192	109	5	877aaf61d8fc40e7013944a0180306dd0bb0557f
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 EFEMP2 SCUBE2 LRP1 GSG1L	1.10e-04	192	109	5	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELE ENTPD1 ABCG2 NOTCH1 SMAD6	1.12e-04	193	109	5	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE8 CBFA2T3 ENTPD1 NOTCH1 SMAD6	1.12e-04	193	109	5	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HTR7 AXL CBFA2T3 ENTPD1 UPK3A	1.15e-04	194	109	5	b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HTR7 AXL CBFA2T3 ENTPD1 UPK3A	1.15e-04	194	109	5	2210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TET2 AXL ENTPD1 CRYBG1 CSMD1	1.15e-04	194	109	5	bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	USP53 CBFA2T3 FCGBP ENTPD1 LAMP3	1.15e-04	194	109	5	e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.18e-04	195	109	5	7bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCell	droplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSIG2 SEMA4G SCUBE2 UPK3A NOTCH1	1.18e-04	195	109	5	d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	USP53 CBFA2T3 FCGBP ENTPD1 LAMP3	1.18e-04	195	109	5	85fee07d71c0393ea42bcf1130566dff4a62f507
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.18e-04	195	109	5	d579150d176e6bd81004b5146de4901ca13a3c3e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	USP53 AHI1-DT AXL ENTPD1 LAMP3	1.18e-04	195	109	5	cb27f6ca8b02438c353c9dff2f76d2656bb5b29a
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A1 COL16A1 AXL EFEMP2 LRP1	1.21e-04	196	109	5	59b5b5a0c123d0423abd19c312514849004b903b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 AXL LDLRAD3 INPP4B LRP1	1.21e-04	196	109	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 AXL LDLRAD3 INPP4B LRP1	1.21e-04	196	109	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNRC6B ICE1 INPP4B CRYBG1 ZNF292	1.21e-04	196	109	5	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A1 COL16A1 AXL EFEMP2 LRP1	1.24e-04	197	109	5	b16add329bb35a558287ede51353010dde5bc029
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SELE ZNF423 LDLRAD3 ENTPD1 SMAD6	1.24e-04	197	109	5	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TET2 AXL ENTPD1 CRYBG1 CSMD1	1.24e-04	197	109	5	a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCell	(2)_MNPs-(2)_Dendritic_Cells\|(2)_MNPs / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	USP53 AXL FCGBP ENTPD1 NOTCH1	1.27e-04	198	109	5	4c1f155298b7d0afddfeb2744b369a1ffd823916
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A1 COL16A1 EFEMP2 LDLRAD3 LRP1	1.27e-04	198	109	5	d3a475be01657a03fcbb0ee0a246b1e90deacaa4
ToppCell	droplet-Trachea-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL9A1 COL16A1 EFEMP2 LDLRAD3 LRP1	1.27e-04	198	109	5	1beed34f469aad07e8f674f0b668d6e1e916403c
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 AXL EFEMP2 SCUBE2 LRP1	1.27e-04	198	109	5	1b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell	droplet-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A1 COL16A1 EFEMP2 LDLRAD3 LRP1	1.27e-04	198	109	5	985022c1722ab7b67675ebe814022a439e715b5e
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	AXL GPX4 FCGBP C2 SOD2	1.27e-04	198	109	5	9a89083280d4253f282300cdf1e61746d1f32407
ToppCell	BAL-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.30e-04	199	109	5	0b20ae65b9340d844e271acda9e116d98fc1cc69
ToppCell	Caecum-(1)_T_cell-(16)_Tfh\|Caecum / shred on region, Cell_type, and subtype	VSIG1 INPP4B ZSCAN20 ADGRE1 EPHA1	1.30e-04	199	109	5	d07d77ae426dd1164d80d7031f14befa0369d3e5
ToppCell	BAL-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.30e-04	199	109	5	bb9e7418468b88cdfaa78788d062362794ea8230
ToppCell	Caecum-T_cell-Tfh\|Caecum / Region, Cell class and subclass	VSIG1 INPP4B ZSCAN20 ADGRE1 EPHA1	1.30e-04	199	109	5	fb40f37d842f170ed101dfa3bffdb8f3b2c94f19
ToppCell	distal-2-Hematologic-Myeloid_Dendritic_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TET2 HTR7 AXL LAMP3 UPK3A	1.30e-04	199	109	5	86ee039189c75e66b97453c20a34d7fb5a31e51d
ToppCell	BAL-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.30e-04	199	109	5	9a0e853693e572c63b135f937b2cffd4dd4026fb
ToppCell	Severe_COVID-19-Myeloid-cDC\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.30e-04	199	109	5	9132c1929d3445fcca49f76f010ca37adeb70315
ToppCell	BAL-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AXL CBFA2T3 ENTPD1 LAMP3 UPK3A	1.30e-04	199	109	5	d017848256704ae7237030868b143c3f0842a9c3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HTR7 CBFA2T3 ENTPD1 LRP1 ADGRE1	1.30e-04	199	109	5	ac866ae110967c5867ff4601939b79861d43df54
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 COL16A1 LDLRAD3 INPP4B LRP1	1.30e-04	199	109	5	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
Drug	p-Menth-3-en-1-ol	SELE IKZF4 SOD2	9.74e-07	5	106	3	CID000011468
Drug	Felbinac [5728-52-9]; Down 200; 18.8uM; PC3; HT_HG-U133A	EFEMP2 FRMPD1 C1RL SEMA4G SLC5A2 STS ABCG2 WIPI2	4.45e-06	200	106	8	4639_DN
Drug	ethylene	CALCOCO1 CBFA2T3 ZFAND4 GUSB C2 ASB1 SOD2	4.61e-06	142	106	7	CID000006325
Drug	epirubicinol	GUSB C2 C6	5.40e-06	8	106	3	CID000128975
Drug	mebeverine-alcohol	GUSB C2	2.15e-05	2	106	2	CID000026649
Drug	0JO	ABCA4 C2	2.15e-05	2	106	2	CID015942668
Drug	Scaeg	GUSB C2	2.15e-05	2	106	2	CID000063010
Drug	otavite	GUSB C2	2.15e-05	2	106	2	CID000010564
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	FAT4 SEMA4G LRP1 SENP6 CRYBG1 ASB1 TBX1	3.50e-05	194	106	7	3807_DN
Drug	Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A	SETD1A FAT4 COL16A1 POM121L2 GYG2 ALK TBX1	3.74e-05	196	106	7	4482_UP
Drug	Ethacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A	FRMPD1 USP29 POM121L2 MMP24 ENTPD1 LRP1 GYG2	3.74e-05	196	106	7	5742_UP
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	FAT4 SLC5A2 MMP24 STS ENTPD1 GYG2 UPK3A	3.74e-05	196	106	7	6396_DN
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A	TMC6 CALCOCO1 TNRC6B STS N4BP2L2 SOD2 SMAD6	3.86e-05	197	106	7	2093_DN
Drug	Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SETD1A USP29 ASB1 ALK TBX1 WIPI2 SOD2	3.86e-05	197	106	7	3192_UP
Drug	Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; MCF7; HT_HG-U133A	NEU3 RCBTB2 DCT ENTPD1 LAMP3 GYG2 ASB1	4.12e-05	199	106	7	6262_UP
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; PC3; HT_HG-U133A	TMC6 C1RL SLC5A2 ALMS1 ENTPD1 UTY ALK	4.25e-05	200	106	7	5761_DN
Disease	Colorectal Carcinoma	TET2 ABCA4 GPX4 ZMIZ1 CUBN CBFA2T3 CAPN10 LRP1 PAN2 ABCG2 TBX1 SOD2 EPHA1 ZNF292	1.25e-07	702	101	14	C0009402
Disease	Colorectal Neoplasms	TET2 ABCA4 GPX4 ZMIZ1 ABCG2 SOD2 EPHA1 ZNF292	5.18e-06	277	101	8	C0009404
Disease	Malignant neoplasm of breast	ABCA4 FRMPD1 GPX4 ELP1 ZMIZ1 CUBN INPP4B KMT2D ABCG2 ALK NOTCH1 ZNF541 SOD2 DNMT3B	1.77e-05	1074	101	14	C0006142
Disease	acute myeloid leukemia (is_marker_for)	TET2 ABCG2 SOD2 DNMT3B	2.43e-05	49	101	4	DOID:9119 (is_marker_for)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL9A1 EFEMP2 NOTCH1 SMAD6	3.33e-05	53	101	4	C4707243
Disease	Kabuki syndrome (implicated_via_orthology)	KMT2D UTY	3.47e-05	3	101	2	DOID:0060473 (implicated_via_orthology)
Disease	Aortic valve disorder	NOTCH1 SMAD6	3.47e-05	3	101	2	cv:C1260873
Disease	Growth abnormality	ZMIZ1 ZNF292	3.47e-05	3	101	2	C0262361
Disease	Diffuse Large B-Cell Lymphoma	KMT2D ABCG2 ALK SOD2	3.86e-05	55	101	4	C0079744
Disease	Aortic valve disorder	NOTCH1 SMAD6	6.93e-05	4	101	2	C1260873
Disease	Aortic Valve Disease 1	NOTCH1 SMAD6	6.93e-05	4	101	2	C3887892
Disease	Breast Carcinoma	GPX4 ELP1 INPP4B KMT2D ABCG2 ALK NOTCH1 SOD2 DNMT3B	9.84e-05	538	101	9	C0678222
Disease	Bicuspid aortic valve	NOTCH1 SMAD6	1.15e-04	5	101	2	C0149630
Disease	uridine measurement	ABCA4 CSMD1 ALK	1.80e-04	32	101	3	EFO_0010546
Disease	Aortic valve calcification	NOTCH1 SMAD6	2.41e-04	7	101	2	C0428791
Disease	non-melanoma skin carcinoma	GPX4 CBFA2T3 CSMD2 MMP24 C2 DNMT3B	3.08e-04	265	101	6	EFO_0009260
Disease	Abnormality of the skeletal system	ZMIZ1 ZNF292	3.20e-04	8	101	2	C4021790
Disease	Squamous cell carcinoma of esophagus	FAT4 KMT2D NOTCH1 SOD2	3.24e-04	95	101	4	C0279626
Disease	suntan	TPCN2 DCT MMP24 DNMT3B	4.41e-04	103	101	4	EFO_0004279
Disease	Mammary Carcinoma, Human	GPX4 ELP1 KMT2D ABCG2 ALK NOTCH1 SOD2 DNMT3B	4.53e-04	525	101	8	C4704874
Disease	Mammary Neoplasms, Human	GPX4 ELP1 KMT2D ABCG2 ALK NOTCH1 SOD2 DNMT3B	4.53e-04	525	101	8	C1257931
Disease	Mammary Neoplasms	GPX4 ELP1 KMT2D ABCG2 ALK NOTCH1 SOD2 DNMT3B	4.64e-04	527	101	8	C1458155
Disease	Male sterility	GPX4 KMT2D SOD2	6.02e-04	48	101	3	C0917731
Disease	Male infertility	GPX4 KMT2D SOD2	6.02e-04	48	101	3	C0021364
Disease	Subfertility, Male	GPX4 KMT2D SOD2	6.02e-04	48	101	3	C0848676
Disease	alkaline phosphatase measurement	SELE TET2 GPX4 ZMIZ1 DCT ZFAND4 NCOR1P1 GUSB N4BP2L2 GSG1L NOTCH1	7.15e-04	1015	101	11	EFO_0004533
Disease	Squamous cell carcinoma of the head and neck	ABCG2 NOTCH1 SOD2	7.62e-04	52	101	3	C1168401
Disease	nervous system disorder	GUSB ABCG2 NOTCH1	8.05e-04	53	101	3	C0027765
Disease	Skin Abnormalities	GORAB SOD2	8.83e-04	13	101	2	C0037268
Disease	Schizophrenia	SETD1A AHI1-DT HTR7 CSMD2 LRP1 CSMD1 ALK TBX1 SOD2 DNMT3B	9.03e-04	883	101	10	C0036341
Disease	prostate carcinoma	TET2 TPCN2 TNRC6B ZMIZ1 ZFAND4 SCUBE2 UPK3A TBX1 SOD2 DNMT3B	9.67e-04	891	101	10	EFO_0001663
Disease	Sarcomatoid Renal Cell Carcinoma	TET2 INPP4B ALK SOD2	9.97e-04	128	101	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	TET2 INPP4B ALK SOD2	9.97e-04	128	101	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	TET2 INPP4B ALK SOD2	9.97e-04	128	101	4	C1266044
Disease	Papillary Renal Cell Carcinoma	TET2 INPP4B ALK SOD2	9.97e-04	128	101	4	C1306837
Disease	Renal Cell Carcinoma	TET2 INPP4B ALK SOD2	9.97e-04	128	101	4	C0007134
Disease	response to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin	VSIG2 CSMD1	1.03e-03	14	101	2	EFO_0005400, GO_0036275, GO_1902518, GO_1902520
Disease	vital capacity	TET2 AHI1-DT ZCCHC8 FRMPD1 POM121L2 ZMIZ1 GUSB PAN2 WSCD2 MOV10 SMAD6 AGAP3	1.06e-03	1236	101	12	EFO_0004312
Disease	Alzheimer's disease (is_implicated_in)	MCM2 LRP1 C2 SOD2	1.12e-03	132	101	4	DOID:10652 (is_implicated_in)
Disease	bitter alcoholic beverage consumption measurement	CPNE8 TNRC6B INPP4B CSMD1	1.15e-03	133	101	4	EFO_0010092
Disease	oral squamous cell carcinoma (is_marker_for)	TET2 KMT2D DNMT3B	1.33e-03	63	101	3	DOID:0050866 (is_marker_for)
Disease	Cardiovascular Abnormalities	ZMIZ1 ZNF292	1.35e-03	16	101	2	C0243050
Disease	amygdala volume change measurement	PKD1L1 CSMD1	1.35e-03	16	101	2	EFO_0021490
Disease	Bladder Neoplasm	INPP4B KMT2D NOTCH1 SOD2	1.39e-03	140	101	4	C0005695
Disease	ascending aortic diameter	TNRC6B CBFA2T3 ENTPD1 MBD5	1.39e-03	140	101	4	EFO_0021787
Disease	Malignant neoplasm of urinary bladder	INPP4B KMT2D NOTCH1 SOD2	1.42e-03	141	101	4	C0005684
Disease	glomerulonephritis (implicated_via_orthology)	AXL C6	1.53e-03	17	101	2	DOID:2921 (implicated_via_orthology)
Disease	atypical femoral fracture, response to bisphosphonate	CPNE8 CSMD1 SMAD6	1.66e-03	68	101	3	EFO_0009958, EFO_0009960
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TET2 INPP4B ALK SOD2	1.70e-03	148	101	4	C0279702
Disease	Feeding difficulties	ZMIZ1 ZNF292	1.71e-03	18	101	2	C0232466
Disease	Age-related macular degeneration	ABCA4 C2	1.71e-03	18	101	2	cv:C0242383
Disease	aortic measurement	CCDC134 TNRC6B CBFA2T3 ENTPD1 LRP1	1.75e-03	251	101	5	EFO_0020865
Disease	colorectal cancer, colorectal adenoma	TET2 ZMIZ1 LRP1 SMAD6	1.88e-03	152	101	4	EFO_0005406, MONDO_0005575
Disease	response to methotrexate, juvenile idiopathic arthritis	ZMIZ1 CSMD1	1.91e-03	19	101	2	EFO_0002609, GO_0031427
Disease	Pancreatic carcinoma	INPP4B SOD2	1.91e-03	19	101	2	C0235974
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 KMT2D DNMT3B	2.12e-03	74	101	3	DOID:3748 (is_marker_for)
Disease	creatinine measurement	TET2 TPCN2 TMC6 TNRC6B SLC34A3 CUBN MMP24 ALMS1 ABCG2 MBD5	2.19e-03	995	101	10	EFO_0004518
Disease	Amphetamine-Related Disorders	ZNF423 CUBN CSMD1	2.20e-03	75	101	3	C0236733
Disease	Amphetamine Abuse	ZNF423 CUBN CSMD1	2.20e-03	75	101	3	C0236807
Disease	Amphetamine Addiction	ZNF423 CUBN CSMD1	2.20e-03	75	101	3	C0236804
Disease	amino acid measurement	FAT4 ALMS1 FBXO31 SENP6 ABCG2 CSMD1 ALK NOTCH1	2.31e-03	678	101	8	EFO_0005134
Disease	circadian rhythm	CPNE8 TNRC6B ASB1 CSMD1	2.42e-03	163	101	4	EFO_0004354
Disease	cystatin C measurement	TPCN2 VSIG2 SLC34A3 ALMS1 NCOR1P1 LRP1	2.63e-03	402	101	6	EFO_0004617
Disease	acute myeloid leukemia (is_implicated_in)	TET2 SOD2 DNMT3B	3.03e-03	84	101	3	DOID:9119 (is_implicated_in)
Disease	congenital heart disease (is_implicated_in)	NOTCH1 TBX1	3.05e-03	24	101	2	DOID:1682 (is_implicated_in)
Disease	Attention deficit hyperactivity disorder	STS ZNF292	3.05e-03	24	101	2	C1263846
Disease	diet measurement	CPNE8 TNRC6B POM121L2 INPP4B MMP24 WSCD2 ABCG2 CSMD1 MBD5 DNMT3B	3.20e-03	1049	101	10	EFO_0008111
Disease	breast cancer, lung cancer	POM121L2 ZMIZ1	3.31e-03	25	101	2	MONDO_0007254, MONDO_0008903
Disease	atrophic macular degeneration	C2 SOD2	3.31e-03	25	101	2	EFO_1001492

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLAGGPPQQFALSNS	AGAP3	16	Q96P47
SQCQGTAQDGGPCQP	EPHA1	371	P21709
PDQNSPQLGVFSGNT	CSMD1	2206	Q96PZ7
CADPGVPQFGIQNNS	CSMD2	3131	Q7Z408
IGGSPCNDLSNVNPA	DNMT3B	646	Q9UBC3
NVNNPCFQSPTPGES	ABCA4	76	P78363
GANTGAQCPPSQQEG	COL16A1	21	Q07092
LLLAGANPDFNCNGP	ASB1	211	Q9Y576
ANPDFNCNGPVNTQG	ASB1	216	Q9Y576
QGGRANCPNSGANAT	GSG1L	46	Q6UXU4
QSPCKNGAICQNFPG	FAT4	3906	Q6V0I7
FLGQNFCPGLNATGN	ABCG2	586	Q9UNQ0
VGSQCPFLPSEQGNN	ALMS1	306	Q8TCU4
GLCQPELQPDSNSNF	C1orf216	21	Q8TAB5
SAGGCRNNSGFPSNP	CAPN10	351	Q9HC96
ANQLPQPSGACANAD	AHI1-DT	96	P0C7V0
GCNPNAKNFEGNSPL	ASB14	141	A6NK59
ENSQLDTSPPCLGGN	BOLA1	116	Q9Y3E2
LSPNCPNQEGNDISA	GORAB	351	Q5T7V8
QLGLGNSGNQPTPCR	RCBTB2	236	O95199
DAQGFTPPQLGASQQ	RIMBP3B	1356	A6NNM3
DAQGFTPPQLGASQQ	RIMBP3C	1356	A6NJZ7
QPTQENSSCGAFGPC	SLC34A3	281	Q8N130
LGPFCQSQNQEVKPG	MCM2	336	P49736
QCIFGPSFDHSNGNP	ANKRD31	991	Q8N7Z5
NCLQGTPGGDFSEPN	PHLDB3	326	Q6NSJ2
STPGTKPNICDGNFN	MMP24	371	Q9Y5R2
SGQCQFCEPTGLANP	PAN2	306	Q504Q3
PGNNFTNECNIPGNF	LDLRAD3	21	Q86YD5
SNPCANGGQCLPFEA	NOTCH1	146	P46531
PGQFQCSTGICTNPA	LRP1	3376	Q07954
APSCPQNVNISGGTF	C2	21	P06681
LPTAQANDPGDCQFT	INPP4B	16	O15327
VAAAEQPAQCGQGQP	FBXO31	431	Q5XUX0
PTCGLCGNFNSTPGQ	MUC19	601	Q7Z5P9
QPGQGSDASNFLQQC	DDIAS	136	Q8IXT1
NFARTGNPNDGNLPC	CES4A	501	Q5XG92
NAIGVLQQCGPPASF	MED21	21	Q13503
LQQCGPPASFNNIQT	MED21	26	Q13503
TNPANGFVECFQNPG	SELE	246	P16581
FNIDPNATQASGNCG	LAMP3	261	Q9UQV4
QGPGNPQCFSLRTEQ	ELP1	16	O95163
SQCAFNGIFLPPLQG	ENTPD1	341	P49961
TAINGAPCTPNGFSN	CBFA2T3	136	O75081
AECNGDKPPENGQQT	ERMN	11	Q8TAM6
SPCNLQPVNSFGFAN	GPR75	496	O95800
VNAGPNTNGSQLFIC	PPIAL4H	101	A0A075B767
PCANSPLGSNQPAQG	GYG2	341	O15488
QPFQIPNGDSSCNQG	CUBN	2136	O60494
TGPAFQEAPCGNNLS	ICE1	1476	Q9Y2F5
QFGGQPCTAPLVAFQ	C6	111	P13671
SNEACGQLRNPQGPF	FCGBP	5046	Q9Y6R7
GQLRNPQGPFATCQA	FCGBP	5051	Q9Y6R7
ILGQPCGDDQNASPS	NCOR1P1	51	Q9H4R4
NPDRACLASNPGLNN	FRMPD1	1021	Q5SYB0
ECPGVGLALPQFFNN	GUSB	406	P08236
SDPSQFCGQQGSPLG	C1RL	106	Q9NZP8
NLQAFQGQSTIPCPA	MBD5	991	Q9P267
FPVNSNSNGGNELCP	COL9A1	31	P20849
GDSSENQALGPQPNQ	CRYBG1	361	Q9Y4K1
PCNQFGKQEPGSNEE	GPX4	101	P36969
CQCEPGFQLGPNNRS	EFEMP2	186	O95967
QTADNCPGTGRQQPF	PRAMEF8	131	Q5VWM4
QPEFGKNNCVSCPGN	SCUBE2	776	Q9NQ36
QGQVCGQSPPFQFRE	CALCOCO1	106	Q9P1Z2
DPENQNVTLNGPGGC	PKD1L1	2421	Q8TDX9
LNGNPQNPYCDGIEG	CPNE8	381	Q86YQ8
GGCVPDFLPQAQDSN	IKZF4	36	Q9H2S9
NLGAASCTLQGPQFG	PUSL1	286	Q8N0Z8
PGSRTPGHQENNNFC	UTY	1086	O14607
PQGSGFCLGQLNLEQ	SMAD6	361	O43541
GCPFPAKLDLQQGQN	MOV10	946	Q9HCE1
DAQGFTPPQLGASQQ	RIMBP3	1356	Q9UFD9
PNFNPVGSNGCFATH	STS	471	P08842
PNPAGLCALSINNDN	WIPI2	156	Q9Y4P8
VCQSPGDAGDQLPNT	SKIV2L	1116	Q15477
PKANGQNQASPCSSG	SETD1A	566	O15047
LSQGANPQPAFGATN	POM121L2	766	Q96KW2
DAPPDNASGCGEQIN	HTR7	61	P34969
SGPHGPTQAQCNNAY	ALK	691	Q9UM73
CHPGFAPSNGQLNFT	ADGRE1	246	Q14246
FCNQTGVFNQGPHSP	CCDC134	146	Q9H6E4
LQGDCTSPGRNPSQF	NEU3	411	Q9UQ49
GLLNEPGQNSCFLNS	USP53	31	Q70EK8
QTADNCPGTGRQQPF	PRAMEF7	131	Q5VXH5
ENGLAPDGASCQGQP	USP42	671	Q9H9J4
PNCDISNGGSQKLFP	ZCCHC8	631	Q6NZY4
CDVNNPPDFLGQNQG	VSIG1	116	Q86XK7
PDQCSEPGGNFAQSP	ZSCAN20	821	P17040
QSNNGVPAGPCSFAE	SEMA4G	801	Q9NTN9
DEQQGSSLPVQNGCP	SLC5A2	576	P31639
PFFTSQTKANGNPAC	ZNF292	1166	O60281
AANTPFNLSCQAQGP	AXL	151	P30530
PSFNTNCNGNPNLDE	USP29	226	Q9HBJ7
PNFQGLCNAPLSAAT	UPK3A	146	O75631
SCPDLQPNGQDLGEN	NRDC	61	O43847
GSNPKVPQQNNFSDC	SENP6	1016	Q9GZR1
IAACPNQDPLQGTTG	SOD2	161	P04179
LLGPNGTQPQFANCS	DCT	166	P40126
AGCLPFNDSQFNPDG	TMEM241	136	Q24JQ0
SNATLNQPCGSPLDG	TMC6	311	Q7Z403
PNANPSDGNNAFFCN	ZNF423	506	Q2M1K9
PAECQPFNTQGLVAG	TBX1	376	O43435
GQPAVSGNQANPAAA	WSCD2	41	Q2TBF2
VLPNIGQSCSPAFGN	ZFAND4	271	Q86XD8
CQVNNPPDFYTNGLG	VSIG2	121	Q96IQ7
PPIFGSSGELQDNCQ	TET2	516	Q6N021
PANGSAPCGSFEQLE	TPCN2	616	Q8NHX9
TSNPGLNSPQFAGQQ	ZMIZ1	206	Q9ULJ6
PCTAPGANPNNAQVT	TNRC6B	126	Q9UPQ9
FLCQNPGEPGLQEAQ	ZNF541	511	Q9H0D2
FAPFGSGCPVNGQSQ	KMT2D	4576	O14686
QQNLGNEPDKYPCNG	N4BP2L2	236	Q92802