Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA helicase activity

RECQL CHD8 FANCM G3BP1 ASCC3

3.27e-05621185GO:0003678
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP42 DOCK2 ABR MYO9B TBC1D2B PREX2 DOCK5 TBC1D22A ARHGAP8

4.23e-052791189GO:0005096
GeneOntologyMolecularFunctionhelicase activity

RECQL CHD8 FANCM G3BP1 HLTF DDX60L ASCC3

4.30e-051581187GO:0004386
GeneOntologyMolecularFunction3'-5' DNA helicase activity

RECQL FANCM ASCC3

1.07e-04161183GO:0043138
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

RECQL CHD8 FANCM G3BP1 HLTF ASCC3

1.08e-041271186GO:0008094
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

LIPJ PPP2R3B PIWIL4 CASR FANCM AGO1 G3BP1 CLN5 PGAP1 PTPRQ ENTPD3 LGALS13 G6PC2 PIWIL3

2.94e-0480711814GO:0016788
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

PIWIL4 RECQL CHD8 FANCM DUS2 AGO1 G3BP1 HLTF DDX60L ASCC3 PIWIL3 REV1

4.39e-0464511812GO:0140640
GeneOntologyMolecularFunctionpiRNA binding

PIWIL4 PIWIL3

5.11e-0461182GO:0034584
GeneOntologyMolecularFunctionfour-way junction helicase activity

RECQL FANCM

5.11e-0461182GO:0009378
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARHGAP42 DOCK2 ABR MYO9B TBC1D2B DOCK10 PREX2 DOCK5 TBC1D22A ARHGAP8

8.59e-0450711810GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARHGAP42 DOCK2 ABR MYO9B TBC1D2B DOCK10 PREX2 DOCK5 TBC1D22A ARHGAP8

8.59e-0450711810GO:0030695
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

RECQL CHD8 FANCM G3BP1 HLTF ASCC3 REV1

9.46e-042621187GO:0140097
GeneOntologyMolecularFunctionATP-dependent activity

MYO9B MYO10 RNF213 RECQL CHD8 FANCM G3BP1 MYO3B HLTF DDX60L ASCC3

1.04e-0361411811GO:0140657
GeneOntologyMolecularFunctiondouble-stranded RNA binding

DUS2 AGO1 TLR3 DDX60L

1.18e-03781184GO:0003725
GeneOntologyMolecularFunctionvolume-sensitive anion channel activity

LRRC8A LRRC8B

1.21e-0391182GO:0005225
GeneOntologyMolecularFunctionUDP phosphatase activity

ENTPD6 ENTPD3

1.21e-0391182GO:0045134
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MYO9B RNF213 RECQL CHD8 FANCM RAB33A G3BP1 ENTPD6 ENTPD3 HLTF RAB7B DDX60L ASCC3

1.39e-0384011813GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MYO9B RNF213 RECQL CHD8 FANCM RAB33A G3BP1 ENTPD6 ENTPD3 HLTF RAB7B DDX60L ASCC3

1.39e-0384011813GO:0016818
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO9B MYO10 MYO3B

1.46e-03381183GO:0000146
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

MICAL1 MICAL2 MICAL3

1.69e-03401183GO:0016709
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYO9B RNF213 RECQL CHD8 FANCM RAB33A G3BP1 ENTPD6 ENTPD3 RAB7B DDX60L ASCC3

2.13e-0377511812GO:0017111
GeneOntologyMolecularFunctionGDP phosphatase activity

ENTPD6 ENTPD3

2.20e-03121182GO:0004382
GeneOntologyMolecularFunctionNAD(P)H oxidase H2O2-forming activity

MICAL1 MICAL2

2.20e-03121182GO:0016174
GeneOntologyMolecularFunctionFAD binding

MICAL1 MICAL2 MICAL3

2.23e-03441183GO:0071949
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

MICAL1 DUS2 MICAL2 MICAL3

2.35e-03941184GO:0050660
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA2D1 ITGAV CACNA2D4

2.54e-03461183GO:0005245
GeneOntologyBiologicalProcessactin filament-based process

AKAP6 DOCK2 MICAL1 CACNA2D1 WASHC4 ABR DSC2 MYO9B PTK7 CYFIP1 WASHC5 MICAL2 PIK3R2 MYO3B ANTXR1 MICAL3 FGF12

1.52e-0591211717GO:0030029
GeneOntologyBiologicalProcesssulfur oxidation

MICAL1 MICAL2

3.19e-0521172GO:0019417
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

ARHGAP42 DOCK2 ABR MYO9B DOCK10 ITGAV PREX2 DOCK5 RAB33A CYFIP1 G3BP1 ARHGAP8

5.60e-0553811712GO:0007264
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

ARHGAP42 ABR MYO9B TBC1D2B DOCK10 PREX2 SNX13 TBC1D22A

7.69e-052441178GO:0043547
GeneOntologyBiologicalProcessDNA duplex unwinding

RECQL CHD8 FANCM G3BP1 ASCC3

8.18e-05781175GO:0032508
GeneOntologyBiologicalProcessnegative regulation of vascular associated smooth muscle contraction

ARHGAP42 DOCK5

9.54e-0531172GO:1904694
GeneOntologyBiologicalProcessregulation of GTPase activity

ARHGAP42 ABR MYO9B TBC1D2B DOCK10 PLXNB2 PREX2 SNX13 TBC1D22A

1.25e-043351179GO:0043087
GeneOntologyBiologicalProcessDNA geometric change

RECQL CHD8 FANCM G3BP1 ASCC3

1.30e-04861175GO:0032392
GeneOntologyBiologicalProcessDNA conformation change

RECQL CHD8 FANCM G3BP1 ASCC3

1.98e-04941175GO:0071103
GeneOntologyCellularComponentfilopodium tip

MYO9B MYO10 CYFIP1 MYO3B

4.07e-06201164GO:0032433
GeneOntologyCellularComponentfilopodium

MYO9B MYO10 ITGAV CYFIP1 MYO3B ANTXR1

6.43e-051231166GO:0030175
GeneOntologyCellularComponentintegrin alphav-beta3 complex

ITGAV PLP1

9.13e-0531162GO:0034683
GeneOntologyCellularComponentfilopodium membrane

MYO10 ITGAV ANTXR1

2.06e-04211163GO:0031527
GeneOntologyCellularComponentintraciliary transport particle A

TTC21A TTC21B

8.36e-0481162GO:0030991
GeneOntologyCellularComponentactin-based cell projection

MYO9B MYO10 ITGAV CYFIP1 MYO3B PTPRQ ANTXR1

9.27e-042781167GO:0098858
DomainFAD-bd

MICAL1 MICAL2 MICAL3

4.49e-0661153IPR002938
DomainFAD_binding_3

MICAL1 MICAL2 MICAL3

4.49e-0661153PF01494
DomainPIWI

PIWIL4 AGO1 PIWIL3

1.25e-0581153PS50822
DomainPiwi

PIWIL4 AGO1 PIWIL3

1.25e-0581153SM00950
DomainPiwi

PIWIL4 AGO1 PIWIL3

1.25e-0581153PF02171
DomainPiwi

PIWIL4 AGO1 PIWIL3

1.25e-0581153IPR003165
DomainRho_GTPase_activation_prot

ARHGAP42 ABR MYO9B PLXNB2 PIK3R2 ARHGAP8

1.72e-05881156IPR008936
DomainPAZ

PIWIL4 AGO1 PIWIL3

1.86e-0591153PS50821
DomainPAZ

PIWIL4 AGO1 PIWIL3

1.86e-0591153SM00949
DomainPAZ

PIWIL4 AGO1 PIWIL3

1.86e-0591153PF02170
DomainPAZ_dom

PIWIL4 AGO1 PIWIL3

1.86e-0591153IPR003100
DomainDHR-1_domain

DOCK2 DOCK10 DOCK5

3.62e-05111153IPR027007
DomainDHR_2

DOCK2 DOCK10 DOCK5

3.62e-05111153PS51651
DomainDHR_1

DOCK2 DOCK10 DOCK5

3.62e-05111153PS51650
DomainDHR-2

DOCK2 DOCK10 DOCK5

3.62e-05111153PF06920
DomainDOCK

DOCK2 DOCK10 DOCK5

3.62e-05111153IPR026791
DomainDOCK_C

DOCK2 DOCK10 DOCK5

3.62e-05111153IPR010703
DomainDOCK-C2

DOCK2 DOCK10 DOCK5

3.62e-05111153PF14429
DomainDHR-2

DOCK2 DOCK10 DOCK5

3.62e-05111153IPR027357
DomainRhoGAP

ARHGAP42 ABR MYO9B PIK3R2 ARHGAP8

3.97e-05621155SM00324
DomainRhoGAP

ARHGAP42 ABR MYO9B PIK3R2 ARHGAP8

4.29e-05631155PF00620
DomainRhoGAP_dom

ARHGAP42 ABR MYO9B PIK3R2 ARHGAP8

4.63e-05641155IPR000198
DomainRHOGAP

ARHGAP42 ABR MYO9B PIK3R2 ARHGAP8

4.63e-05641155PS50238
Domain-

ARHGAP42 ABR MYO9B PIK3R2 ARHGAP8

4.63e-056411551.10.555.10
DomainHelicase_C

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.21e-051071156PF00271
DomainHELICc

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.21e-051071156SM00490
DomainHelicase_C

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.49e-051081156IPR001650
DomainHELICASE_CTER

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.78e-051091156PS51194
DomainHELICASE_ATP_BIND_1

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.78e-051091156PS51192
DomainDEXDc

RECQL CHD8 FANCM HLTF DDX60L ASCC3

5.78e-051091156SM00487
DomainHelicase_ATP-bd

RECQL CHD8 FANCM HLTF DDX60L ASCC3

6.08e-051101156IPR014001
DomainP-loop_NTPase

MYO9B MYO10 RNF213 RECQL CHD8 FANCM RAB33A NWD2 MPP4 MYO3B HLTF RAB7B DDX60L ASCC3 HS6ST3

2.20e-0484811515IPR027417
DomainVDCC_a2/dsu

CACNA2D1 CACNA2D4

2.24e-0441152IPR013680
DomainVGCC_alpha2

CACNA2D1 CACNA2D4

2.24e-0441152PF08473
DomainLRRC8_Pannexin-like

LRRC8A LRRC8B

3.71e-0451152IPR021040
DomainDOCK_N

DOCK2 DOCK5

3.71e-0451152PF16172
DomainDOCK_N

DOCK2 DOCK5

3.71e-0451152IPR032376
DomainVWA_N

CACNA2D1 CACNA2D4

3.71e-0451152IPR013608
DomainVWA_N

CACNA2D1 CACNA2D4

3.71e-0451152PF08399
DomainPannexin_like

LRRC8A LRRC8B

3.71e-0451152PF12534
DomainIg_E-set

VPS26C PLXNB2 ARRDC3 ASCC3 POGLUT2

4.59e-041041155IPR014756
DomainPH

ARHGAP42 ABR MYO10 TBC1D2B DOCK10 PREX2 PHLDB1

5.43e-042291157PF00169
DomainDUF3585

MICAL1 MICAL3

7.74e-0471152IPR022735
DomainDUF3585

MICAL1 MICAL3

7.74e-0471152PF12130
DomainNuclear_transport_factor_2_euk

G3BP1 NXF1

1.03e-0381152IPR018222
DomainNTF2

G3BP1 NXF1

1.03e-0381152PF02136
DomainGDA1_CD39_NTPase

ENTPD6 ENTPD3

1.03e-0381152IPR000407
DomainGDA1_CD39

ENTPD6 ENTPD3

1.03e-0381152PF01150
DomainGDA1_CD39_NTPASE

ENTPD6 ENTPD3

1.03e-0381152PS01238
DomainDEAD/DEAH_box_helicase_dom

RECQL FANCM DDX60L ASCC3

1.07e-03731154IPR011545
DomainDEAD

RECQL FANCM DDX60L ASCC3

1.07e-03731154PF00270
DomainNTF2_DOMAIN

G3BP1 NXF1

1.32e-0391152PS50177
DomainNTF2

G3BP1 NXF1

1.32e-0391152IPR002075
DomainMyosin_head_motor_dom

MYO9B MYO10 MYO3B

1.64e-03381153IPR001609
DomainMYOSIN_MOTOR

MYO9B MYO10 MYO3B

1.64e-03381153PS51456
DomainMyosin_head

MYO9B MYO10 MYO3B

1.64e-03381153PF00063
DomainMYSc

MYO9B MYO10 MYO3B

1.64e-03381153SM00242
DomainPH

ARHGAP42 ABR MYO10 TBC1D2B DOCK10 PREX2 PHLDB1

1.68e-032781157SM00233
DomainPH_DOMAIN

ARHGAP42 ABR MYO10 TBC1D2B DOCK10 PREX2 PHLDB1

1.71e-032791157PS50003
DomainPH_domain

ARHGAP42 ABR MYO10 TBC1D2B DOCK10 PREX2 PHLDB1

1.75e-032801157IPR001849
DomainPeptidase_M28

ERMP1 CPQ

2.38e-03121152PF04389
DomainPeptidase_M28

ERMP1 CPQ

2.38e-03121152IPR007484
Domain-

G3BP1 NXF1

2.80e-031311523.10.450.50
Domain-

PIWIL4 AGO1 PIWIL3

3.03e-034711533.30.420.10
DomainGalectin_CRD

LGALS16 LGALS13

3.74e-03151152IPR001079
Domain-

TMPRSS11B TMPRSS7

3.74e-031511523.30.70.960
DomainGal-bind_lectin

LGALS16 LGALS13

3.74e-03151152PF00337
DomainGal-bind_lectin

LGALS16 LGALS13

3.74e-03151152SM00908
DomainNTF2-like_dom

G3BP1 NXF1

3.74e-03151152IPR032710
DomainGALECTIN

LGALS16 LGALS13

3.74e-03151152PS51304
DomainGLECT

LGALS16 LGALS13

3.74e-03151152SM00276
Domain-

MICAL1 MICAL2 MICAL3

4.97e-035611533.50.50.60
DomainVWA

CACNA2D1 CACNA2D4 ANTXR1

4.97e-03561153PF00092
DomainFAD/NAD-binding_dom

MICAL1 MICAL2 MICAL3

5.23e-03571153IPR023753
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B DOCK10 PREX2 DOCK5 CYFIP1 PIK3R2

3.15e-07175749MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B DOCK10 PREX2 DOCK5 CYFIP1 PIK3R2

4.82e-07184749M41809
PathwayREACTOME_RAC2_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR DOCK10 CYFIP1 PIK3R2

6.14e-0687746MM15600
PathwayREACTOME_RAC2_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR DOCK10 CYFIP1 PIK3R2

6.57e-0688746M41810
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B PREX2 PIK3R2 ARHGAP8

9.30e-06142747MM15576
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGAP42 ABR MYO9B DOCK10 PREX2 PIK3R2

9.62e-0694746MM15598
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B PREX2 PIK3R2 ARHGAP8

1.27e-05149747M41805
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B DOCK10 PREX2 DOCK5 CYFIP1 PIK3R2 ARHGAP8

9.35e-054397410MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGAP42 DOCK2 ABR MYO9B DOCK10 PREX2 DOCK5 CYFIP1 PIK3R2 ARHGAP8

1.15e-044507410M27078
PathwayREACTOME_RAC3_GTPASE_CYCLE

ARHGAP42 ABR DOCK10 CYFIP1 PIK3R2

1.26e-0493745MM15609
PathwayREACTOME_RAC3_GTPASE_CYCLE

ARHGAP42 ABR DOCK10 CYFIP1 PIK3R2

1.33e-0494745M41818
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGAP42 ABR MYO9B DOCK10 PREX2 PIK3R2

1.60e-04155746M41808
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA2D1 DSC2 ITGAV CACNA2D4

6.10e-0474744M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA2D1 DSC2 ITGAV CACNA2D4

6.10e-0474744M39462
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD3

7.46e-048742M27737
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD3

7.46e-048742MM15486
PathwayKEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION

G6PC2 PGM2

9.56e-049742M47621
PathwayPID_RAC1_REG_PATHWAY

DOCK2 ABR PREX2

1.03e-0338743M241
Pubmed

Redox modification of nuclear actin by MICAL-2 regulates SRF signaling.

MICAL1 MICAL2 MICAL3

1.56e-074119324440334
Pubmed

The MICAL proteins and rab1: a possible link to the cytoskeleton?

MICAL1 MICAL2 MICAL3

1.56e-074119315694364
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FRAS1 NRDC DOCK10 CHD8 NOL9 PTK7 DOCK5 WASHC5 ANKIB1 HLTF ANTXR1 MICAL3 NXF1

3.84e-076501191338777146
Pubmed

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.

MICAL1 MICAL2 MICAL3

3.89e-075119312110185
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 KIFBP WASHC4 TBC1D2B CHD8 ERMP1 NCSTN KBTBD2 WASHC5 ANKIB1 LRRC8A

2.18e-065291191114621295
Pubmed

Identification of eight members of the Argonaute family in the human genome.

PIWIL4 AGO1 PIWIL3

3.23e-069119312906857
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

CACNA2D1 FRAS1 RNF213 RECQL ERMP1 NCSTN ITGAV PLXNB2 PTK7 MICAL2 JMJD8 PGAP1 ENTPD6 LRRC8A ANTXR1 POGLUT2

3.54e-0612011191635696571
Pubmed

Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.

TTC21A TTC21B

1.16e-052119232167205
Pubmed

FANCM and RECQL genetic variants and breast cancer susceptibility: relevance to South Poland and West Ukraine.

RECQL FANCM

1.16e-052119229351780
Pubmed

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation.

DOCK2 DOCK5

1.16e-052119225339677
Pubmed

Genetic Interaction of Thm2 and Thm1 Shapes Postnatal Craniofacial Bone.

TTC21A TTC21B

1.16e-052119235645293
Pubmed

Differential regulation of actin microfilaments by human MICAL proteins.

MICAL1 MICAL2

1.16e-052119222331357
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ABR EPHA6 TTC21A RNF213 PRPF38B PTK7 DOCK5 HOXB6 PHLDB1 TBC1D22A MICAL2 TTC21B ANKIB1 ANTXR1 MICAL3 ARHGAP8 TMEM181

1.30e-0514891191728611215
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK2 DOCK10 DOCK5

1.38e-0514119312432077
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

WASHC4 MYO9B DOCK10 RECQL CHD8 NOL9 PHLDB1 CYFIP1 G3BP1 WASHC5 MICAL2 ANKIB1 HLTF DDX60L ASCC3 NXF1

1.56e-0513531191629467282
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

MYO9B RECQL CHD8 ERMP1 NCSTN ITGAV PLXNB2 PTK7 NPFFR2 PIEZO2 WASHC5 JMJD8 MICAL3 ASCC3 ITPRIPL1

1.79e-0512151191515146197
Pubmed

Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression.

ITGAV PLP1

3.47e-053119226311781
Pubmed

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation.

DOCK2 DOCK5

3.47e-053119224913231
Pubmed

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis.

TTC21A TTC21B

3.47e-053119233683377
Pubmed

DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis.

DOCK2 DOCK5

3.47e-053119236804596
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CACNA2D1 SEMA7A CHD8 PREX2 NWD2 AGO1 WASHC5 LRRC8A LRRC8B

3.93e-05475119931040226
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

NCSTN PLXNB2 PTK7 WASHC5 PIK3R2 PGM2

4.15e-05183119631932471
Pubmed

Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.

CACNA2D1 SLC9A9 DDX60L

4.97e-0521119320708005
Pubmed

Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway.

PIWIL4 PIWIL3

6.93e-054119228025795
Pubmed

Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population.

PIWIL4 PIWIL3

6.93e-054119220940137
Pubmed

Role of alpha2/delta subunit in the development of morphine-induced rewarding effect and behavioral sensitization.

CACNA2D1 CACNA2D4

6.93e-054119219596051
Pubmed

The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.

ENTPD6 ENTPD3

6.93e-05411929676430
Pubmed

Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes.

ENTPD6 ENTPD3

6.93e-05411929271669
Pubmed

Myelin proteolipid protein forms a complex with integrins and may participate in integrin receptor signaling in oligodendrocytes.

ITGAV PLP1

6.93e-054119212196561
Pubmed

The gene for the dihydropyridine-sensitive calcium channel alpha 2 subunit (CCHL2A) maps to the proximal region of mouse chromosome 5.

CACNA2D1 PGM2

6.93e-05411921324224
Pubmed

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.

WASHC4 WASHC5

6.93e-054119223676666
Pubmed

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.

LRRC8A LRRC8B

6.93e-054119228193731
Pubmed

The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling.

CACNA2D1 CACNA2D4

6.93e-054119215536090
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 MYO10 DOCK10 SNX13 PHLDB1 MICAL3 ARRDC3 TMEM181

8.31e-05407119812693553
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DSC2 ITGAV PLXNB2 PTK7 PHLDB1 CYFIP1 PIK3R2 MICAL3

1.05e-04421119836976175
Pubmed

Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.

LRRC8A LRRC8B

1.15e-045119235777784
Pubmed

Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.

AKAP6 CHD8

1.15e-045119223071553
Pubmed

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.

DOCK2 DOCK5

1.15e-045119224365888
Pubmed

LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.

LRRC8A LRRC8B

1.15e-045119215094057
Pubmed

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.

LRRC8A LRRC8B

1.15e-045119224790029
Pubmed

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.

PIWIL4 AGO1

1.15e-045119212414724
Pubmed

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

CASR CHD8

1.15e-045119219151705
Pubmed

MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation.

MICAL1 MICAL2

1.15e-045119223911929
Pubmed

The ulcerative colitis marker protein WAFL interacts with accessory proteins in endocytosis.

WASHC4 WASHC5

1.73e-046119220376207
Pubmed

Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin.

SEMA7A ITGAV

1.73e-046119222198947
Pubmed

GARP regulates the bioavailability and activation of TGFβ.

ITGAV TLR3

1.73e-046119222278742
Pubmed

Defining the membrane proteome of NK cells.

DOCK2 ABR MYO9B DOCK10 RNF213 RECQL ERMP1 NCSTN NOL9 HLTF LRRC8A ASCC3 ITPRIPL1

1.88e-0411681191319946888
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

ANKIB1 LRRC8A MICAL3 ARRDC3 TMEM181

1.88e-04153119510718198
Pubmed

Tails of unconventional myosins.

MYO9B MYO10

2.41e-047119211212352
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

NCSTN PLXNB2 PTK7 CYFIP1

3.13e-0494119432062451
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ARHGAP42 DOCK2 ABR SF3A1 PPP2R3B DOCK10 PREX2 DOCK5 CYFIP1 PIK3R2 ARHGAP8

3.17e-049161191132203420
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

PRPF38B ITGAV SDAD1 DOCK5 CYFIP1 AGO1 G3BP1 DISP1

3.19e-04496119831343991
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASHC4 WASHC5

3.21e-048119219922874
Pubmed

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

DOCK2 PREX2

3.21e-048119224659802
Pubmed

Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors.

ASIC2 PIEZO2

3.21e-048119227161260
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

PIWIL4 AGO1

3.21e-048119219345100
Pubmed

A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.

LGALS16 LGALS13

3.21e-048119219497882
Pubmed

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex.

MYO10 DISP1

3.21e-048119233570491
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MICAL1 CACNA2D1 NRDC TTC21A PHLDB1 NWD2 CYFIP1 AGO1 G3BP1 SACS WASHC5 MICAL2 MICAL3 PLP1

3.93e-0414311191437142655
Pubmed

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.

HLTF REV1

4.11e-049119223901102
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYO10 SNX13 SACS MICAL2

4.12e-0410111949872452
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

KIFBP ERMP1 NCSTN ITGAV PTK7 ENTPD6

4.35e-04282119635007762
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

DSC2 SEMA7A SF3A1 TTC21A RNF213 CHD8 ITGAV PLXNB2 TMPRSS11B PTK7 TBC1D22A TLR3 POGLUT2 TMEM181

4.51e-0414511191430550785
Pubmed

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.

ITGAV PLXNB2 ANTXR1

4.99e-0445119319581412
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CACNA2D1 NRDC RECQL PRPF38B ERMP1 NCSTN ITGAV PLXNB2 CYFIP1 G3BP1 ANTXR1 POGLUT2 PGM2

5.11e-0412971191333545068
Pubmed

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.

WASHC4 WASHC5

5.13e-0410119220923837
Pubmed

Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.

PIWIL4 AGO1

5.13e-0410119220721975
Pubmed

Molecular cloning and functional characterization of mouse Nxf family gene products.

PLP1 NXF1

5.13e-0410119215820316
Pubmed

Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.

MYO10 PIEZO2 FGF12

6.04e-0448119323377640
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

EPHA6 SEMA7A PLXNB2 PTK7

7.17e-04117119417145500
Pubmed

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.

LRRC8A LRRC8B

7.49e-0412119232277911
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASHC4 WASHC5

7.49e-0412119219922875
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASHC4 WASHC5

7.49e-0412119227390154
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DSC2 PTK7 DOCK5 RAB33A PHLDB1 PIEZO2 MICAL2 MICAL3

7.83e-04569119830639242
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

WASHC4 PRPF38B CHD8 NCSTN ITGAV PLXNB2 SDAD1 PTK7 CYFIP1 WASHC5 MICAL2 ANTXR1

8.80e-0412031191229180619
Pubmed

Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair.

CHD8 PLP1

8.83e-0413119229920279
Pubmed

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.

DOCK2 DOCK5

8.83e-0413119221930703
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

SEMA7A PLXNB2

8.83e-0413119210520995
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TTC21A RNF213 PRPF38B DOCK5 TMEM260 MYO3B TLR3 ITPRIPL1 NXF1

9.92e-04736119929676528
Pubmed

Cytoneme signaling provides essential contributions to mammalian tissue patterning.

MYO10 DISP1

1.03e-0314119238171360
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

WASHC4 ABR SF3A1 SDAD1 TRIM16 CYFIP1 AGO1 PIK3R2 DDX60L POGLUT2

1.17e-039101191036736316
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA2D1 CACNA2D4

1.18e-0315119220188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA2D1 CACNA2D4

1.18e-0315119224453333
Pubmed

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

TTC21A TTC21B

1.18e-0315119218327258
Pubmed

Hereditary Spastic Paraplegia Overview

WASHC5 PGAP1 PLP1

1.34e-0363119320301682
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

RECQL NCSTN NOL9 CYFIP1 G3BP1 LRRC8A ASCC3

1.42e-03484119731995728
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

SEMA7A SF3A1 CYFIP1 AGO1

1.51e-03143119432560809
Pubmed

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians.

MYO9B G6PC2

1.53e-0317119224647736
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 RNF213 FANCM SACS TTC21B UBR3 MICAL3

1.58e-03493119715368895
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

DSC2 PTK7 CYFIP1

1.60e-0367119321875946
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

MYO9B NOL9 SDAD1 AGO1 G3BP1 PIK3R2

1.62e-03364119624778252
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TBC1D2B RECQL SDAD1 PHLDB1 CYFIP1 MICAL3 ASCC3

1.65e-03497119736774506
Pubmed

A genome-wide association study of sleep habits and insomnia.

CPQ FGF12

1.71e-0318119223728906
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

KIFBP WASHC4 PPP2R3B PLXNB2 SDAD1 G3BP1 ASCC3

1.77e-03503119736217030
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

KPNA5 WASHC4 VPS26C ITGAV WASHC5 TBC1D22A PIK3R2

1.79e-03504119734432599
Pubmed

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

MYO10 PHLDB1 PIEZO2

1.88e-0371119323400010
Pubmed

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

NCSTN ITGAV PTK7

1.88e-0371119312754519
Pubmed

Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation.

CPQ CLN5

1.91e-0319119229514215
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

SF3A1 CYFIP1 G3BP1 HLTF

1.98e-03154119416055720
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

CACNA2D1 DPP10 EPHA6 ASIC2 MYO10 ZNF804A MYO3B DDX60L MMD

1.98e-03814119923251661
GeneFamilyArgonaute/PIWI family

PIWIL4 AGO1 PIWIL3

4.77e-068813408
GeneFamilyVolume regulated anion channel subunits

LRRC8A LRRC8B

1.97e-0458121158
GeneFamilyWASH complex

WASHC4 WASHC5

2.94e-0468121331
GeneFamilyX-linked mental retardation|RNA helicases

FANCM ASCC3

1.06e-03118121168
GeneFamilyGalectins

LGALS16 LGALS13

2.00e-0315812629
GeneFamilyLIM domain containing

MICAL1 MICAL2 MICAL3

2.35e-03598131218
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC9A9 TMEM260 GDF7 RAB7B CLNK DISP1 ITPRIPL1

4.73e-071771187345cebc19f93970a9a46be139208b300081f5493
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

ARHGAP42 SLC9A9 SLC4A3 RAB33A TLR3 CLNK ITPRIPL1

6.14e-071841187b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SLC9A9 SEMA7A DOCK10 RAB33A RAB7B CLNK

6.14e-0718411874f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 MYO9B ITGAV PHLDB1 MICAL2 PGAP1 ANTXR1

6.36e-071851187e58a009aaf342be019a909747b1895d5987d4daf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SLC9A9 SEMA7A DOCK10 RAB7B CLNK ITPRIPL1

6.60e-071861187305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCell367C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DRD5 SEMA7A RAB33A TLR3 RAB7B CLNK ITPRIPL1

6.84e-0718711873748203b62abf51b74dfcfc4f18b3ba831b63a96
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 CACNA2D1 MYO10 DOCK10 DOCK5 PIEZO2 ANTXR1

9.06e-0719511870e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A9 DOCK10 TLR3 ENTPD6 RAB7B CLNK

6.61e-061721186a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 DPP10 ASIC2 PIWIL4 PTK7 NPFFR2

6.84e-06173118695c723b09254ae7131fe5ba0841472502e83269b
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MICAL1 EML5 CPQ ANKIB1 HLTF RAB7B

7.07e-06174118609b091e24317c3f7bac043f04762a533e30793de
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

TTC21A RNF213 ERAP2 PGAP1 TLR3 DDX60L

7.79e-061771186a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP10 NRDC MYO10 DOCK10 CLNK HS6ST3

8.31e-061791186e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

ARHGAP42 SLC9A9 SLC4A3 TLR3 CLNK ITPRIPL1

8.85e-0618111865a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASR ERMP1 PIEZO2 TLR3 LRRC8A PLP1

9.13e-0618211864c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

SEMA7A RNF213 CHD8 ERAP2 DDX60L ARRDC3

9.42e-0618311868f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

AKAP6 SEMA7A GDF7 TLR3 RAB7B CLNK

9.42e-061831186e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 PREX2 DOCK5 PHLDB1 PIEZO2 PLP1

9.72e-061841186a2191dd5546efd357b23e625beb3c5820476f243
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 PREX2 DOCK5 PHLDB1 PIEZO2 PLP1

1.00e-051851186b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

SLC9A9 SEMA7A RAB33A TLR3 RAB7B CLNK

1.03e-051861186962c2dada19185628ead77c32fcb07fa95114247
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 SEMA7A RAB33A RAB7B CLNK ITPRIPL1

1.03e-0518611865916ee851c17d6d9adefeea900b4dfa9642982dc
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CACNA2D1 FRAS1 EPHA6 DOCK10 PREX2

1.03e-051861186310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 CACNA2D1 SLC9A9 MYO10 PIEZO2 PGAP1

1.07e-051871186a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 PREX2 DOCK5 PHLDB1 PIEZO2 PLP1

1.07e-05187118697e520705491c8f52a32025311a9fa7b9176979a
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

SLC9A9 SEMA7A RAB33A TLR3 RAB7B CLNK

1.10e-05188118647bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

SLC9A9 SEMA7A RAB33A TLR3 RAB7B CLNK

1.10e-0518811862331a2bae1383820d598e93aa86c75b101069bac
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AKAP6 CACNA2D1 FRAS1 MYO10 PREX2 PIEZO2

1.13e-051891186203c80030df08ae112f9ae4043709f455d87ce89
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO10 DOCK10 PREX2 DOCK5 PHLDB1 PLP1

1.13e-05189118642ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 PREX2 DOCK5 PHLDB1 PIEZO2 PLP1

1.17e-051901186ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 SLC9A9 ABR DOCK10 RAB7B DDX60L

1.20e-0519111863b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 PREX2 DOCK5 PHLDB1 PIEZO2 PLP1

1.20e-0519111862b056cbe2e82e056e1f798974999378460eb1d16
ToppCell(3)_MNP-(3)_DC_1|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SEMA7A RAB33A TLR3 RAB7B CLNK ITPRIPL1

1.20e-051911186cf0ea54670ed478c3302ccfbee9f6b6706e49fcd
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

SLC9A9 SEMA7A RAB33A TLR3 RAB7B CLNK

1.20e-0519111863480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 ABR MYO9B DOCK10 ZNF804A RAB7B

1.20e-051911186dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CACNA2D1 FRAS1 EPHA6 DOCK10 PREX2

1.20e-051911186fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 ABR MYO9B DOCK10 ZNF804A RAB7B

1.24e-051921186bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRAS1 TMPRSS11B NWD2 PTPRQ FUT5 PIWIL3

1.27e-051931186315840bc48899f3a36d57b19197509de19716e3d
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAV SNX13 CYFIP1 TLR3 ITPRIPL1

1.27e-05193118606b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAV SNX13 CYFIP1 TLR3 ITPRIPL1

1.27e-0519311869c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAV SNX13 CYFIP1 TLR3 ITPRIPL1

1.27e-051931186a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ITGAV SNX13 CYFIP1 TLR3 ITPRIPL1

1.27e-051931186b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA2D1 MYO10 DOCK10 DOCK5 PIEZO2 ANTXR1

1.31e-051941186b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

SEMA7A PREX2 RAB33A GDF7 RAB7B CLNK

1.31e-051941186d21461682fa755f588afe073abb6a777f339c4cc
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 SLC9A9 ABR DOCK10 RAB7B DDX60L

1.35e-051951186ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell367C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SLC9A9 SEMA7A RAB33A RAB7B CLNK ITPRIPL1

1.35e-051951186fca958f73de450ef813444d3dc590353f1c55326
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 SEMA7A DOCK10 GDF7 RAB7B CLNK

1.39e-051961186b71d711be5609115b00a57700885aca608920896
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SLC9A9 ABR MYO9B DOCK10 RAB7B

1.43e-0519711868af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 SLC9A9 ABR MYO9B DOCK10 ZNF804A

1.43e-0519711863912301018d0863144dcfac8d1fa8adc081748d7
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 CACNA2D1 SLC9A9 DOCK10 PIEZO2 ANTXR1

1.43e-05197118673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK2 ABR MYO9B DOCK10 ZNF804A DDX60L

1.43e-051971186f18807124b91310fcd84238484a80ecdba684679
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ABR MYO9B DOCK10 ZNF804A DDX60L

1.47e-051981186e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D231|Adult / Lineage, Cell type, age group and donor

DOCK2 ABR MYO9B DOCK10 RAB7B DDX60L

1.47e-05198118679a415e19cedde13a88f5043d71557363f102322
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ABR MYO9B DOCK10 ZNF804A DDX60L

1.47e-0519811860baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellImmune|World / Lineage, Cell type, age group and donor

DOCK2 ABR MYO9B DOCK10 ZNF804A DDX60L

1.47e-05198118665681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A9 SEMA7A SLC4A3 RAB33A RAB7B CLNK

1.52e-05199118626ea06960e8ea061a71756750b84489609f78162
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 ABR MYO9B TBC1D2B DOCK10 RNF213

1.52e-051991186155b03b859157013e9142e9248551369127d9204
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ABR MYO9B DOCK10 ZNF804A DDX60L

1.52e-0519911867ee2805fd9143eba11bf6832267b62189683608b
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 ZNF804A PIEZO2 MYO3B FGF12

1.56e-0520011864a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-052001186a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-052001186dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-0520011863bba5219453322198e8fdb0921d5f8c403598751
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP42 CACNA2D1 PTK7 DOCK5 ANTXR1 PLP1

1.56e-052001186a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 DPP10 EPHA6 ZNF804A FGF12

1.56e-052001186c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-05200118621bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-052001186a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 ZNF804A PIEZO2 MYO3B FGF12

1.56e-052001186fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 SLC9A9 ABR DOCK10 CYFIP1 TBC1D22A

1.56e-05200118633036d21c1c82109284473a515c4f890b33fdd5c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 ZNF804A PIEZO2 MYO3B FGF12

1.56e-052001186c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 DPP10 EPHA6 ZNF804A FGF12

1.56e-052001186117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 SLC9A9 DPP10 EPHA6 ZNF804A FGF12

1.56e-052001186d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCellSevere-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DOCK5 HOXB6 EML5 HLTF WDR17

3.83e-0514211859c7d5783302974b883bd887f997d094eb5925ec2
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DPP10 EPHA6 NWD2 PTPRQ

4.24e-05145118596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 DOCK10 CACNA2D4 RAB7B CLNK

4.67e-05148118512fa2c4922f03803006c606b1b16e79441e3bb13
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

RNF213 PGAP1 TLR3 RAB7B CLNK

6.00e-051561185afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 CFAP91 EML5 PTPRQ ENTPD3

6.56e-0515911854000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 CFAP91 EML5 PTPRQ ENTPD3

6.56e-0515911857619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 DPP10 EPHA6 NWD2 PTPRQ

7.17e-051621185bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellAdult-Immune-dendritic_cell|Adult / Lineage, Cell type, age group and donor

GLYATL3 SEMA7A DOCK10 RAB7B CLNK

7.82e-051651185073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 CFAP91 EML5 PTPRQ ENTPD3

8.05e-051661185bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 CFAP91 EML5 PTPRQ ENTPD3

8.05e-0516611855e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DSC2 ZNF804A TRIM16 EML5 RAB7B

8.28e-051671185a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

DOCK2 DOCK10 ZNF804A MICAL3 CLNK

8.51e-051681185a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DOCK10 TMEM260 MYO3B HLTF

8.51e-051681185182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXNB2 ENTPD6 ARRDC3 ARHGAP8 DISP1

8.51e-0516811858c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 DOCK2 SLC9A9 FGF12 DDX60L

9.00e-0517011854232fe937909f93d3736988c707b8f95ce993398
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASIC2 DOCK10 NPFFR2 NWD2 WDR17

9.00e-0517011855570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 PREX2 PIEZO2 SACS G6PC2

9.51e-051721185073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell10x5'-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

SEMA7A PREX2 GDF7 RAB7B CLNK

9.51e-051721185243b8bb01cbec5c1bf8802cbf8a6153356b4c384
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SLC9A9 DOCK10 RAB7B CLNK

9.77e-05173118573f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ZNF804A NPFFR2 NWD2 MMD

1.00e-041741185bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ASIC2 PIWIL4 PTK7 NPFFR2

1.00e-041741185e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASIC2 PTK7 NPFFR2 ANTXR1 MMD

1.03e-04175118590e29945aa861082c94bb4f331161adc3a6ef899
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA2D1 FRAS1 NWD2 MICAL2 MMD

1.03e-041751185ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellCOVID-mDC1-|COVID / Condition, Cell_class and T cell subcluster

AKAP6 SLC4A3 GDF7 RAB7B CLNK

1.03e-04175118583a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCellCOVID-mDC1|COVID / Condition, Cell_class and T cell subcluster

AKAP6 SLC4A3 GDF7 RAB7B CLNK

1.03e-041751185b9280444016e21c28131a61df65cc5c56d402412
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA2D1 FRAS1 NWD2 MICAL2 MMD

1.03e-04175118521f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A9 DOCK10 RAB7B CLNK ITPRIPL1

1.06e-0417611855f8c1f917fba49f3b1c0d88b946eca242b668fde
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 PTK7 NPFFR2 ANTXR1 MMD

1.06e-041761185e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK10 ZNF804A RAB7B HS6ST3 PLP1

1.09e-04177118559726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

TTC21A RNF213 PGAP1 TLR3 DDX60L

1.12e-041781185ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

TTC21A RNF213 ERAP2 PGAP1 DDX60L

1.15e-041791185af35ef8a7768cee0c2af0590e5bec35cee6a4714
Diseaseunipolar depression

MICAL1 CACNA2D1 NRDC ASIC2 MYO10 DOCK10 RNF213 ZNF804A NPFFR2 PIEZO2 MICAL2 LGALS13 FGF12 ASCC3 ARHGAP8

5.78e-05120611315EFO_0003761
Diseaseadenosine measurement

AKAP6 ZNF804A

2.16e-0461132EFO_0010453
Diseasefear of minor pain measurement

EPHA6 DOCK5 TBC1D22A

2.27e-04311133EFO_0008340
DiseaseInherited neuropathies

SACS WASHC5 PLP1

4.87e-04401133C0598589
Diseasenephronophthisis (implicated_via_orthology)

TTC21A TTC21B

5.14e-0491132DOID:12712 (implicated_via_orthology)
DiseaseShortened QT interval

CACNA2D1 SLC4A3

7.82e-04111132C0151879
DiseaseOligospermia

PIWIL4 PIWIL3

9.36e-04121132C0028960
Diseasenon-alcoholic fatty liver disease, cirrhosis of liver

CACNA2D1 SLC9A9 DDX60L

1.11e-03531133EFO_0001422, EFO_0003095
Diseaseparathyroid hormone measurement

DPP10 ASIC2 CASR

1.24e-03551133EFO_0004752
Disease4-acetamidobutanoate measurement

PLXNB2 TBC1D22A

1.68e-03161132EFO_0021003
Diseaseidiopathic scoliosis (implicated_via_orthology)

PPP2R3B PTK7

1.68e-03161132DOID:0060250 (implicated_via_orthology)
Diseasecoronary artery calcification

CACNA2D1 SF3A1 DOCK10 NPFFR2 LGALS13 MICAL3 G6PC2

1.77e-034501137EFO_0004723
Diseasealpha-tocopherol measurement

CACNA2D1 VPS26C

2.64e-03201132EFO_0007898
Diseaseautism spectrum disorder

SLC9A9 MYO9B FGF12 HS6ST3

3.10e-031561134EFO_0003756
Diseasedepressive disorder (implicated_via_orthology)

DRD5 PLP1

3.19e-03221132DOID:1596 (implicated_via_orthology)
Diseasechronic widespread pain

CASR SNX13

3.49e-03231132EFO_0010099

Protein segments in the cluster

PeptideGeneStartEntry
LKTLINYYCQERYFH

TTC21B

6

Q7Z4L5
YKIQDIYEIHKEFYD

ABR

141

Q12979
LYHFVTKEDSYANYF

BARGIN

221

Q6ZT62
YVVHTNYDEYAIFLT

AMBP

121

P02760
IYETFYKLYKVFTEH

SLC4A3

836

P48751
QYTEAEEFFVKYKNY

CHD8

661

Q9HCK8
YYQLHKVNISNYSLV

CPQ

346

Q9Y646
EIYYFVEQLAHKFIS

ANTXR1

61

Q9H6X2
YLAVYSIAHALQDIY

CASR

421

P41180
NYFEVDIPKIDVYHY

AGO1

41

Q9UL18
YYTRFKNHEHSYQLE

ANKIB1

601

Q9P2G1
YNAVYQILHYLVDKD

DISP1

421

Q96F81
NHKHAQDYVLTYNYE

DSC2

846

Q02487
LAYDVKQIFHYSYTA

DPP10

141

Q8N608
FIENGYIYHTKYDTA

ERMP1

346

Q7Z2K6
YTQNYTEEVEYFNHK

ARRDC3

71

Q96B67
SEDFVVKNYYLNTYE

CFAP91

386

Q7Z4T9
YYFSYQHVTKVDEVV

ASIC2

66

Q16515
NYIYHLFVNGYKFTE

ENTPD3

426

O75355
QEIYQKAFDLIEHYF

KPNA5

491

O15131
FYEYKCESLNIVHNY

NWD2

386

Q9ULI1
YYRNVHAVVFVYDVT

RAB33A

106

Q14088
YVNYYLHQPQVAAIF

NPFFR2

136

Q9Y5X5
QLTEFFSYEHFYVIY

PPP2R3B

306

Q9Y5P8
HQYVHKTFYEEYQTT

RAB7B

26

Q96AH8
YNQDIVFHKEIAAAY

DRD5

396

P21918
KYYQSIYDTAENINV

NCSTN

451

Q92542
YTVYYVHNIKFDVDC

LRRC8A

281

Q8IWT6
QFVYKLADQIFAYYK

CYFIP1

701

Q7L576
NNYENYIDIVKYVFS

NOL9

381

Q5SY16
LENIVYYKDDTHYFV

MICAL3

286

Q7RTP6
ENYIYYFQSVHESIE

FRAS1

1911

Q86XX4
CHNEYEVKVNGEYIY

LGALS16

96

A8MUM7
EITNHIYYKTISYYN

LIPJ

326

Q5W064
YAQVTHQKAEEIYRY

FANCM

2011

Q8IYD8
HQKAEEIYRYIHYVF

FANCM

2016

Q8IYD8
YDEQLLKNIAFYYEF

DDX60L

361

Q5H9U9
LHQLYQYTQKYYDEI

PLXNB2

1791

O15031
LVLHFLQQYYAIYDS

NXF1

386

Q9UBU9
THLNERAKYVTYQYD

KBTBD2

541

Q8IY47
YHYVSKETFENLIYS

MPP4

476

Q96JB8
LSQQLKAIYVEYGYH

PGM2

461

Q96G03
YFNKHIFSLEQLEYS

MYO10

461

Q9HD67
LENIVYYKDDTHYFV

MICAL1

281

Q8TDZ2
QLYEYAKDLFQQRYH

HS6ST3

406

Q8IZP7
QYSYIDAVCYEKQLH

LRRC8B

101

Q6P9F7
YHEKYKVVELFFYLT

MMD

146

Q15546
EYQKIQYLYEAHLTE

PTPRQ

1526

Q9UMZ3
IKYINYEEQHLYFYK

FADS2B

291

A8MWK0
YQTLELEKEFHYNRY

HOXB6

156

P17509
GKQFELCIYVHYNEY

LGALS13

86

Q9UHV8
LCIYVHYNEYEIKVN

LGALS13

91

Q9UHV8
HYNEYEIKVNGIRIY

LGALS13

96

Q9UHV8
LKVYHQQYQDKSREY

PIK3R2

446

O00459
DNLDHYTNAYAVFYK

GLYATL3

66

Q5SZD4
EALDSFYKHYVQNAI

ITPRIPL1

166

Q6GPH6
QYHDIIQQEYLDTYY

B3GALT2

211

O43825
EFNIHVSASVYAKYY

CCNYL3

166

P0C7X3
HVVNYKYEQYSGDIR

DOCK10

121

Q96BY6
INFYKSNYVQRFHYS

DOCK2

1431

Q92608
HLLQKDSYYVYTQQE

DOCK5

1281

Q9H7D0
QLVDIYEKYQDLYTV

CACNA2D1

56

P54289
FINIIAYNDYVHYIE

CACNA2D4

326

Q7Z3S7
ANKFYVHNDIFRYQD

G3BP1

121

Q13283
YKYNNNTLLYILHYD

ITGAV

831

P06756
IIQHLQKDYRAYYTF

G6PC2

11

Q9NQR9
VKFNVDSNGYYIVHY

ERAP2

621

Q6P179
NNLYYTAAKEIVYFV

EML5

26

Q05BV3
QHIKSDVHLNFYVYY

HLTF

496

Q14527
KYIRYAVQYDNHYTN

DUS2

266

Q9NX74
TYIDYYRQQHKEIVT

PIWIL3

356

Q7Z3Z3
YQENITNACYKYLHE

SACS

2311

Q9NZJ4
VYTHNLYYLAQVYQH

KIFBP

206

Q96EK5
LENIVYYKDCTHYFV

MICAL2

286

O94851
YEIKYYEKEHEQLTY

EPHA6

476

Q9UF33
KFKESVFENYYVIYS

FGF12

146

P61328
RYYQSLQAHLKVDVY

FUT5

221

Q11128
LAHYVYDFLENKAYS

SNX13

676

Q9Y5W8
VYEYKYKREISQHNI

SLC9A9

101

Q8IVB4
TEEVKHVDFYAFSYY

ENTPD6

371

O75354
HQNFYEASLEYVFKI

ARHGAP42

171

A6NI28
LYIDAANNVVYKQYE

GDF7

426

Q7Z4P5
YVDYYKQQYDITVSD

PIWIL4

336

Q7Z3Z4
KVLYLEDFYVTQAYQ

SATL1

611

Q86VE3
YLYYVFKVVHLQASL

PGAP1

756

Q75T13
IYIYQLDHRYNEFKL

WDR17

61

Q8IZU2
AYIEEFLQQYNHYKS

SDAD1

26

Q9NVU7
QHSLFNYFTKLVEQY

SF3A1

201

Q15459
YHDYICQYKEVLKQY

SIX6OS1

111

Q8N1H7
YQVYSLHNVELYEDN

AKAP6

1286

Q13023
SHYYIKYNTIETFNE

ASCC3

986

Q8N3C0
IFDAVIVHKQFYLFY

CLN5

311

O75503
YVLAVFYENKVYNVK

CLNK

346

Q7Z7G1
IQQYLKEDYSFTAYA

RECQL

551

P46063
YSFHDVKDYIQEYLT

RNF213

4141

Q63HN8
TEQFEYAAYIIHAYK

TLR3

751

O15455
FHRSFEYIQDYVNIY

WASHC5

751

Q12768
VHFLAVEKTYYYQGD

TMPRSS11B

36

Q86T26
YDFHAYKEVAQTLYE

REV1

541

Q9UBZ9
VVHEYYNSQTFDYDI

TMPRSS7

681

Q7RTY8
YLNYTQYTVIVGFEH

TMEM181

276

Q9P2C4
YFKVQLYELKTYHEV

PRPF38B

71

Q5VTL8
ILAFEVTIYRHQEYY

PIEZO2

1066

Q9H5I5
EHFYEVAYTVFQYLK

NRDC

516

O43847
HQDQAYDDKIYYFFR

SEMA7A

231

O75326
ALKVYFYIDSYHFEQ

PREX2

1376

Q70Z35
VIYFQAIEEVYYDHL

PHLDB1

1301

Q86UU1
GIIYYSQEKYFHHVQ

TTC21A

11

Q8NDW8
AYVKAHQYTEAIEYY

TTC21A

771

Q8NDW8
HQYTEAIEYYEAAQK

TTC21A

776

Q8NDW8
QRKQKEYFAFIEHYY

TBC1D22A

251

Q8WUA7
VVLKQDSIYYEHFYN

POGLUT2

386

Q6UW63
VENDYTIVYFHYGLN

ARHGAP8

66

P85298
KNYEEARYHLANDIY

ZMYND12

186

Q9H0C1
PENYNTIFQYYHRKT

UBR3

1751

Q6ZT12
RAYVTHYLDKTFYNL

WASHC4

726

Q2M389
QQSLYLHRYYFEVEI

TRIM16

421

O95361
LSKDVYNSEYYHFRQ

PTK7

951

Q13308
HFEQYKVDYTLITFN

TBC1D2B

816

Q9UPU7
QLYAQAYDLYKEIVY

TMEM260

616

Q9NX78
YETYHGVFVNIQYTL

VPS26C

106

O14972
YYKHQEFDNHINSYD

ZNF804A

66

Q7Z570
NTYSYHKVDLPFQEY

JMJD8

101

Q96S16
EFVKRYYYLAFTAHQ

MYO3B

1001

Q8WXR4
VSQEKDERNYHVFYY

MYO9B

326

Q13459
YYFNQHIFKLEQEEY

MYO9B

546

Q13459
QDYEYLINVIHAFQY

PLP1

56

P60201