Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	abnormal superior vena cava morphology	GAS2L2 SETD5 SH3PXD2A	1.50e-05	6	129	3	MP:0006064
Domain	KA1	MARK3 MELK MARK2	6.68e-06	5	165	3	PF02149
Domain	KA1_dom	MARK3 MELK MARK2	6.68e-06	5	165	3	IPR001772
Domain	KA1	MARK3 MELK MARK2	6.68e-06	5	165	3	PS50032
Domain	-	MARK3 MELK MARK2	6.68e-06	5	165	3	3.30.310.80
Domain	KA1/Ssp2_C	MARK3 MELK MARK2	2.31e-05	7	165	3	IPR028375
Domain	HISTONE_H2A	H2AC14 H2AC4 H2AC7 H2AC12	3.13e-05	21	165	4	PS00046
Domain	Histone_H2A	H2AC14 H2AC4 H2AC7 H2AC12	4.56e-05	23	165	4	IPR002119
Domain	H2A	H2AC14 H2AC4 H2AC7 H2AC12	4.56e-05	23	165	4	SM00414
Domain	Histone-fold	CENPT H2AC14 H2AC4 H2AC7 ABTB2 H2AC12	9.34e-05	83	165	6	IPR009072
Domain	C_nuclsd_transpt	SLC28A3 SLC28A1	2.31e-04	3	165	2	IPR008276
Domain	CNT_C_dom	SLC28A3 SLC28A1	2.31e-04	3	165	2	IPR011657
Domain	C_nuclsd_transpt_met_bac	SLC28A3 SLC28A1	2.31e-04	3	165	2	IPR018270
Domain	Gate_dom	SLC28A3 SLC28A1	2.31e-04	3	165	2	IPR011642
Domain	Nucleos_tra2_N	SLC28A3 SLC28A1	2.31e-04	3	165	2	PF01773
Domain	Nuc_orph_rcpt	NR4A3 NR4A1	2.31e-04	3	165	2	IPR003070
Domain	Nucleos_tra2_C	SLC28A3 SLC28A1	2.31e-04	3	165	2	PF07662
Domain	Gate	SLC28A3 SLC28A1	2.31e-04	3	165	2	PF07670
Domain	CNT_N_dom	SLC28A3 SLC28A1	2.31e-04	3	165	2	IPR002668
Domain	Histone_H2A_CS	H2AC14 H2AC7 H2AC12	2.85e-04	15	165	3	IPR032458
Domain	-	CENPT H2AC14 H2AC7 ABTB2 H2AC12	3.61e-04	69	165	5	1.10.20.10
Domain	Histone_H2A_C	H2AC14 H2AC7 H2AC12	4.20e-04	17	165	3	IPR032454
Domain	Histone_H2A_C	H2AC14 H2AC7 H2AC12	4.20e-04	17	165	3	PF16211
Domain	MARK/par1	MARK3 MARK2	4.60e-04	4	165	2	IPR033624
Domain	KIND_dom	PTPN13 KNDC1	7.62e-04	5	165	2	IPR011019
Domain	KIND	PTPN13 KNDC1	7.62e-04	5	165	2	SM00750
Domain	KIND	PTPN13 KNDC1	7.62e-04	5	165	2	PS51377
Domain	Sec23/24_helical_dom	SEC23B SEC23A	1.14e-03	6	165	2	IPR006900
Domain	Sec23_24_beta_S	SEC23B SEC23A	1.14e-03	6	165	2	IPR012990
Domain	zf-Sec23_Sec24	SEC23B SEC23A	1.14e-03	6	165	2	PF04810
Domain	Sec23_trunk	SEC23B SEC23A	1.14e-03	6	165	2	PF04811
Domain	Sec23_helical	SEC23B SEC23A	1.14e-03	6	165	2	PF04815
Domain	HOOK	CCDC88B CCDC88C	1.14e-03	6	165	2	PF05622
Domain	Sec23_BS	SEC23B SEC23A	1.14e-03	6	165	2	PF08033
Domain	Hook-related_fam	CCDC88B CCDC88C	1.14e-03	6	165	2	IPR008636
Domain	Sec23/24_trunk_dom	SEC23B SEC23A	1.14e-03	6	165	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC23B SEC23A	1.14e-03	6	165	2	IPR006895
Domain	EF-hand_5	NOX5 USP32 SLC25A23	1.35e-03	25	165	3	PF13202
Domain	Histone_H2A/H2B/H3	H2AC14 H2AC4 H2AC7 H2AC12	1.51e-03	56	165	4	IPR007125
Domain	Histone	H2AC14 H2AC4 H2AC7 H2AC12	1.51e-03	56	165	4	PF00125
Domain	PDZ	DLG5 GIPC2 MPDZ PTPN13 MAST1 PARD3	1.59e-03	141	165	6	PF00595
Pathway	REACTOME_METALLOPROTEASE_DUBS	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	9.02e-06	37	109	5	M27580
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	H2AC11 VPS72 SETD6 H2AC14 H2AC4 H2AC7 DOT1L SMYD3 H2AC12 BRWD1	4.82e-05	272	109	10	M29619
Pathway	WP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM	MAP2 DISC1 RET MARK2 AGRN	7.66e-05	57	109	5	M48326
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 HIVEP1 MAP2 DSP MARK3 MPDZ GIGYF1 ARHGEF17 MELK ARFGEF3 CCDC88C PTPN13 SH3PXD2A SAMD11 COBL IRS2 MTCL1 MARK2 PARD3 SRRM2 ABTB2 SEC23B	3.54e-10	861	172	22	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRFN1 MRPL55 MYOM3 FBXL12 PER1 ZNF395 TBC1D17 PLEKHH3 CCDC88C TKFC SLC2A4RG ZNF341 SETD5 MAP3K11 COBL CACNA1H IRS2 DOT1L ESPL1 AGRN ABTB2 BAHCC1	3.26e-08	1105	172	22	35748872
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	H2AC11 MYH10 DSP SEPTIN9 PAICS H2AC14 H2AC4 H2AC7 UQCRC2 SRRM2 ATP5F1A H2AC12 SEC23A RPL18	1.27e-07	477	172	14	31300519
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SEPTIN9 PER1 CAVIN3 GIGYF1 NR4A1 TBC1D17 SLX9 POLR3D DNAJC11 SUGP1 KNDC1 IRS2 ESPL1 ABTB2 SEC23B RPL8 SEC23A WWC1 RPL18 WDTC1	2.43e-07	1038	172	20	26673895
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	H2AC11 DLG5 MYH10 DSP MARK3 SEPTIN9 DNTTIP2 LRCH3 H2AC14 SLX9 NAT10 H2AC7 UQCRC2 MARK2 SRRM2 ATP5F1A H2AC12 RPL8 RPL18	2.78e-07	949	172	19	36574265
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	GABRE CPAMD8 MYH10 FYTTD1 MAP2 CACNA2D2 MARK3 SEPTIN9 RBBP8NL LRCH3 SBK1 ARFGEF3 DFFB PTPN13 SETD5 SH3PXD2A NAT10 KNDC1 MAST1 COBL CACNA1H HSD11B2 PARD3 SMYD3	3.67e-07	1489	172	24	28611215
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MARK3 MPDZ GIGYF1 LRCH3 CCDC88C PTPN13 SH3PXD2A DNAJC11 IRS2 MTCL1 MARK2 PARD3 WWC1	3.92e-07	446	172	13	24255178
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FYTTD1 STARD8 CAND2 ABCF3 GALNT1 PAICS DNTTIP2 POLR3D PTPN13 ZNF341 SETD5 NAT10 N4BP2L2 DOT1L PARD3 ESPL1 AGRN ATP5F1A LRRC17 BRWD1	4.79e-07	1084	172	20	11544199
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYH10 MARK3 STXBP5 SEPTIN9 ARHGEF17 ARFGEF3 SETD5 MAST1 COBL CACNA1H MTCL1 SRRM2	9.87e-07	407	172	12	12693553
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DLG5 MYH10 FYTTD1 MAP2 DSP MRPL55 HRNR RCOR2 PTPN13 MAMDC2 NAT10 SUGP1 UQCRC2 SRRM2 AGRN TNXB SEC23B RPL8 RPL18	1.95e-06	1082	172	19	38697112
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	H2AC11 DSP TRAPPC5 HRNR PAICS PLEKHH3 H2AC14 H2AC4 NAT10 H2AC7 ATP5F1A H2AC12 SEC23B CNP SEC23A RPL18	5.09e-06	844	172	16	25963833
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	MYH10 DSP HRNR PAICS TKFC TONSL DOT1L ATP5F1A SEC23B	7.31e-06	264	172	9	32814769
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	MYH10 ABCF3 DSP SEPTIN9 CAVIN3 PAICS DNTTIP2 H2AC14 SLX9 DECR2 IRS2 MTCL1 UQCRC2 SRRM2 GNL1 ATP5F1A SEC23B CNP RPL8 SEC23A RPL18	7.50e-06	1415	172	21	28515276
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	ABCF3 DSP SEPTIN9 PAICS NAT10	7.95e-06	55	172	5	33067418
Pubmed	Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.	MARK3 MARK2 PARD3	9.77e-06	9	172	3	18562307
Pubmed	The genomic organization of the histone clusters on human 6p21.3.	H2AC11 H2AC7 H2AC12	9.77e-06	9	172	3	10384058
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	RBL1 PIWIL4 HRNR CCDC88C H2AC14 SH3PXD2A H2AC7 CACNA1H SRRM2 ATP5F1A H2AC12 RPL8	1.05e-05	513	172	12	25798074
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	TNC MARK3 STXBP5 TRAPPC5 PAICS PTPN13 DNAJC11 MAST1 DECR2 MARK2 PARD3	1.08e-05	430	172	11	32581705
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	MARK3 ARHGEF17 IRS2 MARK2 PARD3 SRRM2	1.22e-05	102	172	6	15778465
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DLG5 DSP MARK3 SEPTIN9 MPDZ PAICS PTPN13 IRS2 MARK2 PARD3 ATP5F1A CNP RPL8 RPL18	1.27e-05	708	172	14	39231216
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	STARD8 CAND2 VPS72 HRNR MELK RCOR2 GARIN3 GAS2L2 ZNF341 SETD5 SH3PXD2A NAT10 LTBP1 DOT1L ABTB2 ATP5F1A SMYD3 SEC23A WDTC1	1.38e-05	1242	172	19	30973865
Pubmed	Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry.	H2AC11 H2AC4 H2AC7 H2AC12	1.43e-05	30	172	4	16319397
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	POU2F1 CCDC88C IFT88 NAT10 KNDC1 MARK2 DOT1L PIGO SMYD3 RPL18 WDTC1	1.64e-05	450	172	11	16751776
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	MYH10 DSP HRNR PAICS DNTTIP2 H2AC4 NAT10 UQCRC2 SRRM2 ATP5F1A H2AC12 RPL8 RPL18	2.01e-05	641	172	13	36057605
Pubmed	Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	2.43e-05	69	172	5	11689053
Pubmed	The tenascin gene family in axon growth and guidance.	TNC TNXB	2.43e-05	2	172	2	9321695
Pubmed	The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.	NR4A3 NR4A1	2.43e-05	2	172	2	30696767
Pubmed	NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.	NR4A3 NR4A1	2.43e-05	2	172	2	28249906
Pubmed	Activated ALK signals through the ERK-ETV5-RET pathway to drive neuroblastoma oncogenesis.	RET ALK	2.43e-05	2	172	2	29321660
Pubmed	Molecular signatures of thyroid follicular neoplasia.	NR4A3 NR4A1	2.43e-05	2	172	2	20668010
Pubmed	Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.	ZNF395 SLC2A4RG	2.43e-05	2	172	2	14625278
Pubmed	Cloning and functional characterization of mammalian homologues of the COPII component Sec23.	SEC23B SEC23A	2.43e-05	2	172	2	8898360
Pubmed	The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.	NR4A3 NR4A1	2.43e-05	2	172	2	25410408
Pubmed	Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.	NR4A3 NR4A1	2.43e-05	2	172	2	17515897
Pubmed	Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.	SEC23B SEC23A	2.43e-05	2	172	2	30065114
Pubmed	Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.	NR4A3 NR4A1	2.43e-05	2	172	2	21205929
Pubmed	FBW7-mediated ubiquitination and destruction of PD-1 protein primes sensitivity to anti-PD-1 immunotherapy in non-small cell lung cancer.	PDCD1 FBXW7	2.43e-05	2	172	2	36104103
Pubmed	Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.	TNC TNXB	2.43e-05	2	172	2	17202312
Pubmed	Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.	MARK3 MARK2	2.43e-05	2	172	2	20733003
Pubmed	Distribution of tenascin-C and -X, and soft X-ray analysis of the mandibular symphysis during mandible formation in the human fetus.	TNC TNXB	2.43e-05	2	172	2	15455729
Pubmed	Tenascin variants: ligands and expression.	TNC TNXB	2.43e-05	2	172	2	7509489
Pubmed	The effects of tenascin C knockdown on trabecular meshwork outflow resistance.	TNC TNXB	2.43e-05	2	172	2	23882691
Pubmed	Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia.	CACNA1A CACNA2D2	2.43e-05	2	172	2	16474392
Pubmed	Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.	NR4A3 NR4A1	2.43e-05	2	172	2	20411565
Pubmed	Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts.	TNC TNXB	2.43e-05	2	172	2	8856503
Pubmed	Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury.	NR4A3 NR4A1	2.43e-05	2	172	2	19153266
Pubmed	DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction.	MPDZ CCDC88C	2.43e-05	2	172	2	31268831
Pubmed	HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.	NR4A3 NR4A1	2.43e-05	2	172	2	23247046
Pubmed	A nanoscale view of junctophilin-2 and ryanodine receptors.	JPH2 RYR2	2.43e-05	2	172	2	27909078
Pubmed	Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility.	JPH2 RYR2	2.43e-05	2	172	2	31591206
Pubmed	Invasion of melanoma in double knockout mice lacking tenascin-X and tenascin-C.	TNC TNXB	2.43e-05	2	172	2	12359049
Pubmed	The change in tenascin expression in mouse uterus during early pregnancy.	TNC TNXB	2.43e-05	2	172	2	9013311
Pubmed	The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.	CACNA1A CACNA2D2	2.43e-05	2	172	2	16928863
Pubmed	YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.	TNC RET TNXB	2.53e-05	12	172	3	10101119
Pubmed	Viral immune modulators perturb the human molecular network by common and unique strategies.	H2AC11 H2AC14 H2AC4 H2AC7 SMYD3 H2AC12	2.54e-05	116	172	6	22810585
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A MYH10 MAP2 DSP TNC MARK3 SEPTIN9 GRM1 ARHGEF17 LRCH3 KNDC1 MAST1 UQCRC2 MARK2 SLC25A23 ATP5F1A CNP RPL8 SEC23A RPL18	2.95e-05	1431	172	20	37142655
Pubmed	Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	3.19e-05	73	172	5	14657027
Pubmed	Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	3.19e-05	73	172	5	9566873
Pubmed	A standardized nomenclature for mammalian histone genes.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	3.41e-05	74	172	5	36180920
Pubmed	The human and mouse replication-dependent histone genes.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	4.13e-05	77	172	5	12408966
Pubmed	Precise characterization of human histones in the H2A gene family by top down mass spectrometry.	H2AC11 H2AC4 H2AC7	4.16e-05	14	172	3	16457589
Pubmed	The human H2A and H2B histone gene complement.	H2AC11 H2AC14 H2AC12	4.16e-05	14	172	3	10064132
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYH10 ABCF3 DSP SEPTIN9 MELK PAICS DNTTIP2 SLX9 NAT10 RTCA UQCRC2 PARD3 SRRM2 AGRN ATP5F1A CNP RPL8 SEC23A RPL18	4.44e-05	1353	172	19	29467282
Pubmed	Roles of tau protein in health and disease.	MAP2 MARK3 TTBK1 MARK2	4.59e-05	40	172	4	28386764
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYH10 CAVIN3 LRCH3 SLX9 NAT10 MTCL1 UQCRC2 ATP5F1A CNP RPL8 RPL18 FBXW7	4.91e-05	601	172	12	33658012
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	FYTTD1 MARK3 LRCH3 PTPN13 C1orf226 COBL EBAG9 MARK2 PARD3 CNP	5.10e-05	421	172	10	36976175
Pubmed	CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.	NR4A3 UQCRC2 ATP5F1A	5.18e-05	15	172	3	34048907
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	MARK3 GIGYF1 LRCH3 SH3PXD2A MARK2 ATP5F1A	5.25e-05	132	172	6	16944949
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	DLG5 MYH10 FYTTD1 DSP MARK3 SEPTIN9 MRPL55 SLX9 TKFC NAT10 DECR2 UQCRC2 MARK2 PARD3 GNL1 ALK ATP5F1A CNP SEC23A	5.29e-05	1371	172	19	36244648
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DLG5 MYH10 DSP MARK3 SEPTIN9 HRNR PAICS DNTTIP2 LRCH3 SLX9 DNAJC11 NAT10 UQCRC2 MARK2 ATP5F1A CNP RPL8 RPL18	5.55e-05	1257	172	18	36526897
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	GIPC2 DSP SEPTIN9 H2AC4 TKFC DNAJC11 NAT10 UQCRC2 GNL1 ATP5F1A CNP RPL8 RPL18	5.82e-05	711	172	13	33022573
Pubmed	An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.	MYH10 SEPTIN9 EXOC8 TNXB	6.13e-05	43	172	4	30975701
Pubmed	MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.	MYH10 MAP2 MARK3	6.35e-05	16	172	3	14594945
Pubmed	Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	7.03e-05	86	172	5	11080476
Pubmed	Proteomic characterization of the human sperm nucleus.	H2AC11 MYH10 DSP HRNR H2AC4 GARIN3 TKFC H2AC7 GNL1 RPL18	7.08e-05	438	172	10	21630459
Pubmed	ALK, ROS1 and RET rearrangements in lung squamous cell carcinoma are very rare.	RET ALK	7.27e-05	3	172	2	26973202
Pubmed	ALK, ROS1 and RET fusions in 1139 lung adenocarcinomas: a comprehensive study of common and fusion pattern-specific clinicopathologic, histologic and cytologic features.	RET ALK	7.27e-05	3	172	2	24629636
Pubmed	NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors.	NR4A3 NR4A1	7.27e-05	3	172	2	22996661
Pubmed	Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1.	NR4A3 NR4A1	7.27e-05	3	172	2	18945812
Pubmed	Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1.	MAP2 MARK3	7.27e-05	3	172	2	12879020
Pubmed	Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.	CACNA1A CACNA1H	7.27e-05	3	172	2	26216687
Pubmed	Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.	TNC TNXB	7.27e-05	3	172	2	7694605
Pubmed	Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.	SLC28A3 SLC28A1	7.27e-05	3	172	2	17453413
Pubmed	Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.	NR4A3 NR4A1	7.27e-05	3	172	2	15964844
Pubmed	NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.	NR4A3 NR4A1	7.27e-05	3	172	2	29343483
Pubmed	The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse.	TNC TNXB	7.27e-05	3	172	2	12823230
Pubmed	Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement.	RET ALK	7.27e-05	3	172	2	25723109
Pubmed	The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress.	RTCA CNP	7.27e-05	3	172	2	30355738
Pubmed	Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation.	NR4A3 NR4A1	7.27e-05	3	172	2	10523643
Pubmed	GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma.	GIPC2 RET	7.27e-05	3	172	2	33947839
Pubmed	Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.	RET ALK	7.27e-05	3	172	2	25855381
Pubmed	Orphan nuclear receptors in T lymphocyte development.	NR4A3 NR4A1	7.27e-05	3	172	2	12223510
Pubmed	Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder.	NR4A3 NR4A1	7.27e-05	3	172	2	20659174
Pubmed	Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl.	MAP2 COBL	7.27e-05	3	172	2	29689199
Pubmed	Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.	MAP2 KNDC1	7.27e-05	3	172	2	21385318
Pubmed	Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.	RET ALK	7.27e-05	3	172	2	34310819
Pubmed	B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors.	NR4A3 NR4A1	7.27e-05	3	172	2	29414782
Pubmed	Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies.	RET ALK	7.27e-05	3	172	2	22327622
Pubmed	Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.	NR4A3 NR4A1	7.27e-05	3	172	2	36482877
Pubmed	Clinical outcomes with pemetrexed-based systemic therapies in RET-rearranged lung cancers.	RET ALK	7.27e-05	3	172	2	27056998
Interaction	YWHAB interactions	DLG5 HIVEP1 FOXO6 MAP2 MARK3 ZNF395 GIGYF1 ARHGEF17 MELK PAICS CCDC88C H2AC4 PTPN13 TKFC SH3PXD2A USP32 MAST1 IRS2 MTCL1 MARK2 DOT1L PARD3 SRRM2 ATP5F1A SEC23B WWC1 FBXW7	8.48e-08	1014	168	27	int:YWHAB
Interaction	YWHAG interactions	DLG5 MYH10 HIVEP1 FOXO6 MAP2 DSP MARK3 DISC1 MPDZ ZNF395 GIGYF1 ARHGEF17 MELK DNTTIP2 LRCH3 CCDC88C PTPN13 TTBK1 SH3PXD2A SAMD11 COBL IRS2 MTCL1 MARK2 PARD3 SRRM2 ATP5F1A SEC23B WWC1 FBXW7	1.39e-07	1248	168	30	int:YWHAG
Interaction	H3C15 interactions	H2AC11 MYH10 DSP DNTTIP2 H2AC14 H2AC4 NAT10 TONSL H2AC7 SRRM2 H2AC12	1.36e-06	207	168	11	int:H3C15
Interaction	YWHAH interactions	DLG5 HIVEP1 FOXO6 MAP2 DSP MARK3 MPDZ ZNF395 GIGYF1 ARHGEF17 MELK ARFGEF3 CCDC88C SLX9 PTPN13 SH3PXD2A SAMD11 MAST1 COBL IRS2 MTCL1 MARK2 PARD3 SRRM2 SEC23B WWC1	1.51e-06	1102	168	26	int:YWHAH
Interaction	PTPN13 interactions	LRFN1 MARK3 GIGYF1 RET DFFB PTPN13 SH3PXD2A PTPRQ EBAG9 PARD3	7.80e-06	202	168	10	int:PTPN13
Interaction	H1-5 interactions	H2AC11 DSP PIWIL4 ARHGEF17 MELK H2AC14 H2AC4 ZNF341 TONSL H2AC7 ALK H2AC12 RPL8 RPL18 FBXW7	8.12e-06	463	168	15	int:H1-5
Interaction	SH3PXD2A interactions	LRFN1 MARK3 GIGYF1 MELK PTPN13 SH3PXD2A MARK2 WDTC1	1.21e-05	128	168	8	int:SH3PXD2A
Interaction	YWHAE interactions	DLG5 MYH10 HIVEP1 MARK3 DISC1 ZNF395 GIGYF1 RXFP3 MELK LRCH3 CCDC88C PTPN13 SH3PXD2A SAMD11 MAST1 LTBP1 IRS2 MARK2 DOT1L PARD3 SRRM2 AGRN ATP5F1A SEC23B WWC1 FBXW7	1.57e-05	1256	168	26	int:YWHAE
Interaction	H3-4 interactions	H2AC11 DNAH10 JPH2 ZNF395 APLF H2AC14 H2AC4 NAT10 TONSL H2AC7 DOT1L SMYD3 H2AC12 WDTC1	2.45e-05	448	168	14	int:H3-4
Interaction	H2AC7 interactions	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12 RPL18 FBXW7	3.20e-05	107	168	7	int:H2AC7
Interaction	GSK3A interactions	DLG5 MAP2 MARK3 MPDZ ARFGEF3 PTPN13 H2AC7 MAP3K11 COBL MTCL1 MARK2 SRRM2 WWC1 RPL18	3.60e-05	464	168	14	int:GSK3A
Interaction	MAGOH interactions	H2AC11 MYH10 FYTTD1 DFFB H2AC7 DOT1L SRRM2 RPL8 RPL18 FBXW7	7.69e-05	264	168	10	int:MAGOH
GeneFamily	Fibronectin type III domain containing	LRFN1 TNC MYOM3 FNDC1 NEO1 PTPRQ TNXB	5.53e-05	160	110	7	555
GeneFamily	PDZ domain containing	DLG5 GIPC2 MPDZ PTPN13 MAST1 PARD3	3.34e-04	152	110	6	1220
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA2D2 CACNA1H	5.14e-04	26	110	3	253
GeneFamily	Histones	H2AC11 H2AC14 H2AC4 H2AC7 H2AC12	7.14e-04	116	110	5	864
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1	NAPSA NR4A1 ADAMDEC1 LTBP1 IRS2 TNXB	6.23e-06	69	172	6	M1145
Coexpression	GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN	MAP2 ICAM4 GRM1 DFFB TKFC HEATR6 SRRM2 HRH3 BAHCC1	6.52e-06	197	172	9	M8165
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1	NAPSA NR4A1 ADAMDEC1 LTBP1 IRS2 TNXB	1.01e-05	75	172	6	MM868
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	NAPSA SOX5 CACNA2D2 TNC LURAP1L ARFGEF3 PTPN13 PARD3 WWC1	5.24e-08	188	172	9	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 SEPTIN9 NPAS3 CCDC88C PTPN13 HSD11B2 ABTB2	5.48e-08	189	172	9	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 SMYD3 WWC1	6.00e-08	191	172	9	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 SMYD3 WWC1	6.86e-08	194	172	9	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 SMYD3 WWC1	7.16e-08	195	172	9	9406866f99555198a9be311fbd65751b70f35446
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AC11 ICAM4 C2CD4A MELK KLF1 SAMD11 HSD11B2 ESPL1	4.96e-07	179	172	8	804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 STXBP5 CCDC88C PTPN13 HSD11B2 ABTB2	5.86e-07	183	172	8	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 NPAS3 CCDC88C PTPN13 HSD11B2 ABTB2	6.37e-07	185	172	8	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early\|lymph-node_spleen / Manually curated celltypes from each tissue	MYH10 OR11G2 NOX5 WIPF3 MELK PAICS PLEKHH3 KLF1	6.91e-07	187	172	8	61d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 STXBP5 CCDC88C PTPN13 HSD11B2 ABTB2	6.91e-07	187	172	8	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAP2 SEPTIN9 SH3RF2 COBL MTCL1 DOT1L PARD3 WWC1	7.19e-07	188	172	8	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 WWC1	7.19e-07	188	172	8	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	NAPSA CACNA2D2 LURAP1L ARFGEF3 PTPN13 COBL PARD3 WWC1	7.79e-07	190	172	8	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 NPAS3 CCDC88C HSD11B2 AGRN ABTB2	8.43e-07	192	172	8	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 WWC1	8.43e-07	192	172	8	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 WWC1	8.43e-07	192	172	8	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 CCDC88C PTPN13 HSD11B2 AGRN ABTB2	9.11e-07	194	172	8	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	facs-Heart-RV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA CENPT DSP CDHR5 TKFC SLC25A23 PIGO	9.69e-07	135	172	7	99e7ac9b1139fe4ff036f6f048a8f1cc514c1fb9
ToppCell	facs-Heart-RV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA CENPT DSP CDHR5 TKFC SLC25A23 PIGO	9.69e-07	135	172	7	1fe684ed5913ae757ad6befbbe12d1bee481dd12
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CACNA2D2 GBX1 RXFP3 GRM1 FNDC1 C9orf50 ALK	1.56e-06	145	172	7	8b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA NR4A1 MELK RCOR2 H2AC4 CIITA TONSL	2.77e-06	158	172	7	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	Influenza_Severe-cDC\|World / Disease group and Cell class	MYH10 NR4A3 NR4A1 TKFC ADAMDEC1 KLF1 AGRN	3.55e-06	164	172	7	c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GIPC2 DSP RBL1 WIPF3 KLHDC8A MTCL1 AGRN	3.69e-06	165	172	7	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIPC2 MAP2 DSP WIPF3 FABP12 ARFGEF3 MTCL1	3.84e-06	166	172	7	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIPC2 MAP2 DSP WIPF3 FABP12 ARFGEF3 MTCL1	3.84e-06	166	172	7	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AC11 STARD8 RBL1 STXBP5 RET H2AC4 C1orf226	4.67e-06	171	172	7	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AC11 STARD8 RBL1 STXBP5 RET H2AC4 C1orf226	4.67e-06	171	172	7	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	N4BP2L1 SLC28A3 SBK1 CCDC88C DFFB CIITA MAST1	5.04e-06	173	172	7	49030c2dd04b592655df1a667e2f90efb499e0a5
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	N4BP2L1 SLC28A3 SBK1 CCDC88C DFFB CIITA MAST1	5.04e-06	173	172	7	1cfbab6603f8baf8e238837bb72740c43a7dc0ec
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA SOX5 GIMAP1 SBK1 CIITA CNP WWC1	5.24e-06	174	172	7	28ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP\|lymph-node_spleen / Manually curated celltypes from each tissue	ARHGEF17 MELK H2AC14 H2AC4 MAMDC2 H2AC12 BAHCC1	5.65e-06	176	172	7	de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCell	facs-BAT-Fat-24m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAPSA GIMAP1 NR4A1 CIITA IRS2 RPL8 RPL18	6.31e-06	179	172	7	932fc2bd62ff024068004825beda1ea493f2d650
ToppCell	CV-Severe-4\|Severe / Virus stimulation, Condition and Cluster	PDCD1 MYH10 TNC NR4A3 CAVIN3 NR4A1 PAICS	6.54e-06	180	172	7	cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MYH10 CCDC88C PTPN13 SAMD11 HSD11B2 ABTB2	6.54e-06	180	172	7	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TNC RYR2 FNDC1 MAMDC2 LTBP1 TNXB ABTB2	7.29e-06	183	172	7	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	7.29e-06	183	172	7	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	7.82e-06	185	172	7	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	8.10e-06	186	172	7	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AC11 H2AC4 H2AC7 SRRM2 H2AC12 RPL8 RPL18	8.10e-06	186	172	7	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H2AC11 H2AC4 H2AC7 SRRM2 H2AC12 RPL8 RPL18	8.10e-06	186	172	7	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	Control-Epithelial-ATII\|World / Disease state, Lineage and Cell class	NAPSA CACNA2D2 LURAP1L ARFGEF3 PTPN13 PARD3 WWC1	8.10e-06	186	172	7	f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYH10 TNC JPH2 RYR2 CACNA1H LTBP1	8.39e-06	187	172	7	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GABRE MAP2 SH3RF2 PTPRQ COBL MTCL1 WWC1	8.39e-06	187	172	7	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MYH10 CACNA2D2 PTPN13 LTBP1 HSD11B2 ABTB2	8.39e-06	187	172	7	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	MYH10 TNC JPH2 CAVIN3 FNDC1 CACNA1H LTBP1	8.69e-06	188	172	7	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CPAMD8 MYH10 CCDC88C PTPN13 HSD11B2 ABTB2	8.99e-06	189	172	7	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MAP2 JPH2 CAVIN3 ARHGEF17 RYR2 LTBP1	8.99e-06	189	172	7	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 JPH2 GBX1 ARHGEF17 RYR2 CACNA1H LTBP1	8.99e-06	189	172	7	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 JPH2 GBX1 ARHGEF17 RYR2 CACNA1H LTBP1	8.99e-06	189	172	7	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MAP2 JPH2 CAVIN3 ARHGEF17 RYR2 LTBP1	8.99e-06	189	172	7	2b5f1b4f173a224342ea4f10b193ee33b7662699
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MAP2 JPH2 CAVIN3 ARHGEF17 RYR2 LTBP1	8.99e-06	189	172	7	43e131458d8a4b120f7a5fb3d0c5650abded15f6
ToppCell	droplet-Lung-21m-Epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIPC2 DSP MYOM3 FABP12 ARFGEF3 KNDC1 COBL	9.31e-06	190	172	7	50a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 TNC JPH2 ARHGEF17 FNDC1 SAMD11 LTBP1	9.31e-06	190	172	7	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	droplet-Heart-nan-24m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM4 NR4A3 MELK H2AC4 TONSL	9.38e-06	73	172	5	30374f4d30519ca8cd9582da1f9f906420e50244
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAPSA SOX5 CPAMD8 CACNA2D2 NR4A1 PTPN13 WWC1	9.63e-06	191	172	7	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	9.63e-06	191	172	7	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	MYH10 TNC FNDC1 SAMD11 MAMDC2 LTBP1 LRRC17	9.63e-06	191	172	7	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	MYH10 TNC FNDC1 SAMD11 MAMDC2 LTBP1 LRRC17	9.63e-06	191	172	7	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	SOX5 MYH10 JPH2 ARHGEF17 RYR2 CACNA1H LTBP1	9.63e-06	191	172	7	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	NAPSA SOX5 MPDZ ARFGEF3 COBL PARD3 WWC1	9.96e-06	192	172	7	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	facs-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIPC2 DSP RET ARFGEF3 COBL MTCL1 WWC1	9.96e-06	192	172	7	cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	1.03e-05	193	172	7	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAPSA GIMAP1 SBK1 CIITA CNP RPL8 RPL18	1.03e-05	193	172	7	a808eb426b4ce9ddf7d6556b083abd9232a218b1
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAPSA GIMAP1 SBK1 CIITA CNP RPL8 RPL18	1.03e-05	193	172	7	e1d0b2d2d6b65d32922e22d092848ac4200669d5
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIPC2 RET ARFGEF3 DCAF12L1 COBL MTCL1 WWC1	1.03e-05	193	172	7	4a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIPC2 RET ARFGEF3 DCAF12L1 COBL MTCL1 WWC1	1.03e-05	193	172	7	68adc680deb2f1a29d3cca19c13b9f6271dd4d60
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIPC2 RET ARFGEF3 DCAF12L1 COBL MTCL1 WWC1	1.03e-05	193	172	7	819e6ee2ffa3e31bf9a2d57c99d9e3eac7072765
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAPSA SOX5 CACNA2D2 ARFGEF3 PTPN13 PARD3 WWC1	1.03e-05	193	172	7	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 CPAMD8 ARFGEF3 PTPN13 COBL PARD3 WWC1	1.03e-05	193	172	7	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	facs-Lung-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIPC2 DSP RET ARFGEF3 COBL MTCL1 WWC1	1.03e-05	193	172	7	db5e43e0b571737e7006365bdf0575340b8b900b
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMPRSS11E RET RBBP8NL TTBK1 HSD11B2 ESPL1 WWC1	1.07e-05	194	172	7	d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MYH10 STXBP5 PTPN13 HSD11B2 KLHL8 ABTB2	1.07e-05	194	172	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 DNAH10 MPDZ ARFGEF3 COBL PARD3 WWC1	1.10e-05	195	172	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	NAPSA SOX5 ARFGEF3 PTPN13 COBL PARD3 WWC1	1.10e-05	195	172	7	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 MYH10 RYR2 LURAP1L MAMDC2 PARD3 TNXB	1.10e-05	195	172	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 DNAH10 MPDZ ARFGEF3 COBL PARD3 WWC1	1.10e-05	195	172	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	NAPSA SOX5 ARFGEF3 PTPN13 COBL PARD3 WWC1	1.10e-05	195	172	7	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC CAVIN3 PAICS FNDC1 AGRN CNP RPL8	1.10e-05	195	172	7	eaadc79f53b1cb208c6f7999925f318e1378197f
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 TNC NPAS3 SAMD11 LTBP1 TNXB ABTB2	1.10e-05	195	172	7	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	NAPSA CACNA2D2 ARFGEF3 PTPN13 COBL PARD3 WWC1	1.10e-05	195	172	7	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NAPSA CACNA2D2 DSP ICAM4 RBBP8NL PTPRQ AGRN	1.14e-05	196	172	7	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	H2AC11 RBL1 MELK H2AC14 H2AC4 ESPL1 H2AC12	1.14e-05	196	172	7	1964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC CAVIN3 PAICS FNDC1 AGRN CNP RPL8	1.14e-05	196	172	7	d4df86ce289835e76763213641989fde77935a16
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1A CACNA2D2 TMPRSS11E RET TBC1D17 MAST1 HSD11B2	1.18e-05	197	172	7	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH10 TNC FNDC1 SAMD11 MAMDC2 LTBP1 TNXB	1.18e-05	197	172	7	16758f181ef07c60aee63072e1da9572c5c85414
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 JPH2 CAVIN3 ARHGEF17 RYR2 CACNA1H LTBP1	1.18e-05	197	172	7	d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FOXO6 CACNA2D2 TMPRSS11E RET TONSL MAST1 HSD11B2	1.22e-05	198	172	7	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RBL1 TRAPPC5 ICAM4 MELK SBK1 TONSL ESPL1	1.22e-05	198	172	7	d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	MYH10 TNC MPDZ NR4A1 RYR2 SH3PXD2A RPL18	1.26e-05	199	172	7	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	NPAS3 MPDZ PTPN13 LTBP1 IRS2 PARD3 SLC25A23	1.26e-05	199	172	7	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH10 TNC JPH2 RYR2 FNDC1 CACNA1H LTBP1	1.30e-05	200	172	7	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	MYH10 TNC RYR2 LURAP1L FNDC1 LTBP1 TNXB	1.30e-05	200	172	7	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	MYH10 TNC LURAP1L FNDC1 MAMDC2 LTBP1 TNXB	1.30e-05	200	172	7	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	NAPSA CACNA2D2 DSP ARFGEF3 PTPN13 COBL WWC1	1.30e-05	200	172	7	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Skin-Keratinocytes\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	GALNT1 DSP NR4A1 PTPN13 COBL PARD3 FBXW7	1.30e-05	200	172	7	59d72395199bc30df0e811fbc99149694e208860
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SOX5 MYH10 TNC ARHGEF17 RYR2 PLEKHH3 FNDC1	1.30e-05	200	172	7	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	ASK428-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	NAPSA CACNA2D2 NR4A1 ARFGEF3 PTPN13 RPL8 RPL18	1.30e-05	200	172	7	8919d7371b9d9a061d52664532980c6ea20d0473
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	SOX5 MYH10 TNC LURAP1L FNDC1 MAMDC2 TNXB	1.30e-05	200	172	7	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDR1 MYH10 TNC FNDC1 SAMD11 LTBP1 LRRC17	1.30e-05	200	172	7	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	MYH10 TNC SAMD11 MAMDC2 LTBP1 TNXB LRRC17	1.30e-05	200	172	7	c2c6f687c49ba790174b27c7b8b084af30b34c86
Drug	Lumicolchicine gamma [6901-14-0]; Up 200; 10uM; HL60; HT_HG-U133A	DISC1 SEPTIN9 ICAM4 NR4A3 NR4A1 LRCH3 N4BP2L2 AGRN CNP BRWD1 WDTC1	2.89e-07	196	171	11	1317_UP
Disease	Akinetic Petit Mal	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C0001890
Disease	Epilepsy, Absence, Atypical	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C0751124
Disease	Absence Seizure Disorder	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C4553705
Disease	Juvenile Absence Epilepsy	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C4317339
Disease	Childhood Absence Epilepsy	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C4281785
Disease	Epilepsy, Minor	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C4552765
Disease	Absence Epilepsy	CACNA1A CACNA2D2 CACNA1H	5.39e-06	7	160	3	C0014553
Disease	congenital dyserythropoietic anemia type II (implicated_via_orthology)	SEC23B SEC23A	2.92e-05	2	160	2	DOID:0111401 (implicated_via_orthology)
Disease	craniolenticulosutural dysplasia (implicated_via_orthology)	SEC23B SEC23A	2.92e-05	2	160	2	DOID:0070307 (implicated_via_orthology)
Disease	Hydrocephalus	MPDZ CCDC88C	8.73e-05	3	160	2	cv:C0020255
Disease	Congenital hydrocephalus	MPDZ CCDC88C	8.73e-05	3	160	2	cv:C0020256
Disease	Congenital dyserythropoietic anemia, type I	KLF1 SEC23B	1.74e-04	4	160	2	C0271933
Disease	Roberts syndrome (implicated_via_orthology)	SEC23B SEC23A	1.74e-04	4	160	2	DOID:5325 (implicated_via_orthology)
Disease	Congenital dyserythropoietic anemia, type II	KLF1 SEC23B	1.74e-04	4	160	2	C1306589
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK3 MARK2	1.74e-04	4	160	2	DOID:0070356 (implicated_via_orthology)
Disease	Alzheimer's disease (implicated_via_orthology)	SOX5 HIVEP1 MAP2 RCOR2	2.63e-04	57	160	4	DOID:10652 (implicated_via_orthology)
Disease	Congenital dyserythropoietic anemia, type III	KLF1 SEC23B	2.89e-04	5	160	2	C0271934
Disease	Congenital dyserythropoietic anemia	KLF1 SEC23B	2.89e-04	5	160	2	C0002876
Disease	Congenital dyserythropoietic anemia	KLF1 SEC23B	4.32e-04	6	160	2	cv:C0002876
Disease	unipolar depression, bipolar disorder, mental or behavioural disorder	NPAS3 IFT88	4.32e-04	6	160	2	EFO_0000677, EFO_0003761, MONDO_0004985
Disease	hydrocephalus (is_implicated_in)	MPDZ CCDC88C	4.32e-04	6	160	2	DOID:10908 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement	N4BP2L1 DNAH10 TMPRSS11E SUGP1 RSRP1 KLHL8 BRWD1	5.65e-04	260	160	7	EFO_0008317
Disease	temporal lobe epilepsy (biomarker_via_orthology)	CACNA1A MAP2 GRM1	6.29e-04	31	160	3	DOID:3328 (biomarker_via_orthology)
Disease	cathepsin Z measurement	ZNF831 SUGP1	8.01e-04	8	160	2	EFO_0008074
Disease	Aqueductal Stenosis	MYH10 CCDC88C	8.01e-04	8	160	2	C2936786
Disease	Spinocerebellar Ataxia Type 2	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0752121
Disease	Spinocerebellar Ataxia Type 1	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0752120
Disease	Spinocerebellar Ataxia Type 5	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0752123
Disease	Spinocerebellar Ataxia Type 7	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0752124
Disease	Ataxia, Spinocerebellar	CACNA1A GRM1 CCDC88C	8.28e-04	34	160	3	C0087012
Disease	brain measurement, neuroimaging measurement	SOX5 ABCF3 MAP2 MARK3 CCDC88C NEO1 SH3PXD2A SUGP1 PARD3 BAHCC1	8.78e-04	550	160	10	EFO_0004346, EFO_0004464
Disease	Spinocerebellar Ataxia Type 4	CACNA1A GRM1 CCDC88C	9.02e-04	35	160	3	C0752122
Disease	serum alanine aminotransferase measurement	DLG5 MARK3 SETD6 DISC1 SEPTIN9 TMPRSS11E PIWIL4 ZNF341 APOL5 SUGP1 N4BP2L2 KLHL8 BRWD1	9.45e-04	869	160	13	EFO_0004735
Disease	amnestic disorder (implicated_via_orthology)	IRS2 HRH3	1.03e-03	9	160	2	DOID:10914 (implicated_via_orthology)
Disease	sexual dimorphism measurement	SOX5 LRRC66 GIPC2 FOXO6 VPS72 DNAH10 CACNA2D2 RBL1 SBK1 H2AC4 ZNF341 H2AC7 MAP3K11 LTBP1 DOT1L	1.04e-03	1106	160	15	EFO_0021796
Disease	vital capacity	CAND2 MAP2 CACNA2D2 DSP SEPTIN9 PER1 JPH2 SLC28A3 RYR2 SLC2A4RG ZNF341 LTBP1 MTCL1 DOT1L PARD3 TNXB	1.16e-03	1236	160	16	EFO_0004312
Disease	tenascin measurement	TNC TNXB	1.28e-03	10	160	2	EFO_0008296
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	DSP RYR2	1.28e-03	10	160	2	DOID:0050431 (is_implicated_in)
Disease	nasopharyngeal neoplasm	N4BP2L1 FOXO6 SLC28A3 CIITA C6orf15	1.43e-03	151	160	5	EFO_0004252
Disease	Cognitive impairment	RYR2 SMYD3	1.56e-03	11	160	2	HP_0100543
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	N4BP2L1 DNAH10 TMPRSS11E SUGP1 RSRP1 BRWD1	1.61e-03	229	160	6	EFO_0004639, EFO_0008317
Disease	Oligospermia	PIWIL4 BRWD1	1.86e-03	12	160	2	C0028960
Disease	vitamin D measurement	SOX5 FOXO6 TMPRSS11E HRNR SUGP1 KLHL8 SEC23A	2.47e-03	336	160	7	EFO_0004631
Disease	response to methotrexate, aspartate aminotransferase measurement	TMC2 MAP2	2.55e-03	14	160	2	EFO_0004736, GO_0031427
Disease	platelet component distribution width	STARD8 GIPC2 MARK3 SEPTIN9 ZNF831 SUGP1 RSRP1 N4BP2L2 IRS2 TNXB BRWD1	2.84e-03	755	160	11	EFO_0007984
Disease	generalised epilepsy	CACNA2D2 PER1 RYR2	2.85e-03	52	160	3	EFO_0005917
Disease	mean corpuscular hemoglobin concentration	SOX5 GIPC2 MARK3 RBL1 GIGYF1 NEO1 SLC2A4RG KLF1 MAST1 RSRP1 N4BP2L2 IRS2 DOT1L PIGO	2.86e-03	1105	160	14	EFO_0004528
Disease	Hemoglobin F Disease	KLF1 CACNA1H	2.93e-03	15	160	2	C0019025
Disease	risk-taking behaviour	SOX5 HIVEP1 MAP2 MARK3 SLC28A3 RYR2 NEO1 TTBK1 DNAJC11 TNXB BAHCC1	3.11e-03	764	160	11	EFO_0008579
Disease	body mass index, osteoarthritis	CACNA1H LTBP1 BRWD1	3.17e-03	54	160	3	EFO_0004340, MONDO_0005178
Disease	alcohol consumption measurement	SOX5 CACNA1A DLG5 MYH10 MARK3 NPAS3 SLC28A3 SBK1 DFFB COBL PARD3 AGRN SEC23B WWC1 BAHCC1	3.20e-03	1242	160	15	EFO_0007878
Disease	Tremor, Rubral	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0750940
Disease	Ataxia, Appendicular	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0750937
Disease	Ataxia, Motor	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0278161
Disease	Ataxia, Sensory	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0240991
Disease	phosphatidylcholine 38:6 measurement	SUGP1 LTBP1	3.34e-03	16	160	2	EFO_0010388
Disease	Abnormal coordination	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0520966
Disease	Ataxia, Truncal	CACNA1A CACNA2D2	3.34e-03	16	160	2	C0427190
Disease	apolipoprotein B measurement	N4BP2L1 DNAH10 TMPRSS11E C2CD4A GIGYF1 SLC2A4RG C6orf15 SUGP1 RSRP1 BRWD1	3.44e-03	663	160	10	EFO_0004615
Disease	response to statin	SOX5 DISC1 SLC28A3	3.51e-03	56	160	3	GO_0036273
Disease	brain infarction	GIPC2 ALK	4.22e-03	18	160	2	EFO_0004277
Disease	Insulin Resistance	NR4A3 NR4A1 IRS2	4.27e-03	60	160	3	C0021655
Disease	Insulin Sensitivity	NR4A3 NR4A1 IRS2	4.27e-03	60	160	3	C0920563
Disease	skin sensitivity to sun	RXFP3 PARD3	4.70e-03	19	160	2	EFO_0004795
Disease	Cannabis use, age at onset	SLC28A3 RYR2	4.70e-03	19	160	2	EFO_0004847, EFO_0007585
Disease	facial asymmetry measurement	SOX5 NPAS3	4.70e-03	19	160	2	EFO_0009751

Protein segments in the cluster

Peptide	Gene	Start	Entry
KPGTSFGISVLRALR	CACNA1A	571	O00555
TPGGRIREKLSRAKS	BAHCC1	1601	Q9P281
IRTSLEKKRRGSGVP	DISP3	801	Q9P2K9
PALLTATRRAVRKRG	C9orf50	81	Q5SZB4
GRGPLLGITDKRVSR	APLF	26	Q8IW19
VQSLRRALSGRKGPA	CAVIN3	186	Q969G5
GQRRKLSSRFPVGRS	CCDC88B	1391	A6NC98
SLGRRTLRPAVVGVK	CACNA2D2	831	Q9NY47
TARPRGRLVQSLSKA	CIITA	546	P33076
KTRSSRAGLQFPVGR	H2AC11	16	P0C0S8
RPLASLSGGQKSRVA	ABCF3	606	Q9NUQ8
FRSVRLRDLGPGKSV	AGRN	1186	O00468
GRATLRLRSKGPATV	GIPC2	221	Q8TF65
RALRSPRKFGVAGRS	DFFB	11	O76075
IGRASRKLGRLAKPT	FABP12	26	A6NFH5
RGRRKRASAGTPSLS	DOT1L	1086	Q8TEK3
RAGGSPTAVRSILTK	CDHR5	766	Q9HBB8
LLRSSRGRIVTVGSP	HSD11B2	206	P80365
RRFSGRPKLSGRLGL	CDR1	151	P51861
RGLLVRSPVSKSAAA	DISC1	91	Q9NRI5
SKTRRRVGLKAPGII	ATP5F1A	166	P25705
RGRKLSGDQITLPTT	EBAG9	31	O00559
GSGILSRSRAKTVPN	RCOR2	11	Q8IZ40
SPVSRIGLFIKAGSR	UQCRC2	56	P22695
KGLRAGSRSRSAEPR	MTCL1	1781	Q9Y4B5
DPLGRGSKRLSRSVT	NOX5	526	Q96PH1
KARLLSRPLRGVSGK	MAMDC2	566	Q7Z304
LTRSKRKGSARDGPR	MELK	541	Q14680
VVRTDSLKGRRGRLP	NR4A1	336	P22736
GLLRSQARTRAKGPG	ARHGEF17	426	Q96PE2
SSRGIRPGLTTVLAR	DNAJC11	246	Q9NVH1
LLGKLRRAESRTSVG	JPH2	226	Q9BR39
VLSLSGRKLREFPRG	LRCH3	61	Q96II8
TVTRGRGFPKTGLLL	MAGEB3	191	O15480
LVRGLGLKNSRSSPS	GIGYF1	851	O75420
GRLQALRSLSGTPKS	WWC1	516	Q8IX03
AELRKASPGSVRSRV	LRRC17	16	Q8N6Y2
DSRRVKGSRSLPRVS	LRFN1	566	Q9P244
LARERTPLVGKAGSS	CCDC88C	1856	Q9P219
PERRGKGRSGTLATL	PER1	151	O15534
ARGTIGARRTGQPLK	PDCD1	196	Q15116
TKRRGIALASLGGPI	KLHL8	401	Q9P2G9
SERTRRTSKPGGAAL	LTBP1	81	Q14766
GAEVGPLRKAKSSRR	FOXO6	71	A8MYZ6
GSLKPGTESISRRLS	HRNR	146	Q86YZ3
GLRRLGGPQASLSTK	DECR2	216	Q9NUI1
VRRRKSLGGKVVTPL	DLG5	706	Q8TDM6
VRIRSAAALSVPGKR	HEATR6	1016	Q6AI08
RSRPQERVLGSTSGK	FLVCR1-DT	26	Q8TAF5
TGSRVGKLPEASRIL	GABRE	61	P78334
DPSSVLKKSRRRGRG	GNL1	266	P36915
GLIAARRTGRLRGTK	RPL8	236	P62917
DRSLRGGPKATRRAV	EXOC8	401	Q8IYI6
GGPKATRRAVSQLIR	EXOC8	406	Q8IYI6
LRSTVALTAARGRGK	NAT10	276	Q9H0A0
AGSGLRKKQRRLPRS	LRRC66	341	Q68CR7
VSGLRSPITIQRSGK	MAST1	961	Q9Y2H9
PGIEGLSRRRKKRTS	POU2F1	371	P14859
AAARTRKGLGPSSIL	PTPRQ	1261	Q9UMZ3
ARVASPTSGVKRLSL	IRS2	1096	Q9Y4H2
SRGRRKLTATEGPGS	RBBP8NL	631	Q8NC74
RRLPRSNSLGAGGKI	C6orf15	176	Q6UXA7
RSGLIRARLKGAAVS	GALNT1	186	Q10472
TAGVTAPGGKSRRRR	GBX1	251	Q14549
STRRLILVGRTGAGK	GIMAP1	26	Q8WWP7
SGRGRQKLASAPLRL	ESPL1	1316	Q14674
SSKGERLSARLRALP	IFT88	756	Q13099
GVIAETAPSKRGRRS	KLF1	256	Q13351
LRRKEPSSLGSVGVT	C1orf226	66	A1L170
RAIEATTKGISARGP	GAS2L2	441	Q8NHY3
RLSGAKSPRRSRGFL	FNDC1	181	Q4ZHG4
LLRQDKRPRSGSTGS	ARFGEF3	2086	Q5TH69
GRPVLRTTKILGSRD	CPAMD8	281	Q8IZJ3
ISVPRVRRASSKGGG	DSP	156	P15924
AGARRALLETASPRK	CENPT	36	Q96BT3
ASPRKLSGQTRTIAR	CENPT	46	Q96BT3
RSGTGAARLRKVPLL	COBL	1246	O75128
LSVGSKRRRTGGSLR	FBXW7	6	Q969H0
RGLPGSGKSTLARVI	CNP	56	P09543
RTRAAQRKTGPVSLA	BRWD1	1576	Q9NSI6
LGRKVPESLVRSLRG	LURAP1L	16	Q8IV03
SRGTERPRSLKRGSK	HRH3	311	Q9Y5N1
PRLSLNGVRFKRISG	MARK2	756	Q7KZI7
PRLSLNGVRFKRISG	MARK3	721	P27448
PTARAGVAVTALGKR	KLHDC8A	66	Q8IYD2
TVSRTLEKLKPGTRG	KNCN	106	A6PVL3
VTRLARSKGVGPALS	KNDC1	1066	Q76NI1
LESSSGPARRKLRLA	DCAF12L1	391	Q5VU92
KTRSSRAGLQFPVGR	H2AC4	16	P04908
KTRSSRAGLQFPVGR	H2AC7	16	P20671
KTRSSRAGLQFPVGR	H2AC12	16	Q96KK5
KTRSSRAGLQFPVGR	H2AC14	16	Q99878
RSPGRKVLLAGASSQ	GRM1	21	Q13255
SSLGRAPSLKRRGQC	CACNA1H	1146	O95180
SPRLAVRKRAVGALG	CAND2	186	O75155
RKRLGTGLSPTSVVL	DNAH10	4221	Q8IVF4
LKRTVLTESGSGSRP	SBK1	351	Q52WX2
AGKGEAIRIRSILRS	RYR2	2411	Q92736
LLPGRARGAKSRTTA	C2CD4A	21	Q8NCU7
RGSSSGTPKLIQRAL	MAP3K11	631	Q16584
VSTLKNRLRRGGPIS	MYH10	1921	P35580
RDRLRGKGLPTGRSS	PTPN13	201	Q12923
RAVLRVPSAAGRRKA	OR11G2	261	Q8NGC1
FSARGGRTLGLLVKR	PARD3	291	Q8TEW0
GSALGRRTKRAQSPK	ICAM4	21	Q14773
PAILRVRTRGGVGKA	OR1N1	221	Q8NGS0
SAILRAPSAQGRRKA	OR1P1	236	Q8NH06
VVRTDSLKGRRGRLP	NR4A3	361	Q92570
AKGRGRRPVKTLELT	GARIN3	106	Q8TC56
GRPTGASARRLSKVT	RXFP3	311	Q9NSD7
PSIRSRDLTLGGVKK	POLR3D	41	P05423
GKGARRLGSLVLTSL	PLEKHH3	136	Q7Z736
KTVARTPLGQRSRSG	SRRM2	1526	Q9UQ35
STGINRPKRTGSLAL	RBL1	776	P28749
RKIRLTVRGLSAPGL	FBXL12	231	Q9NXK8
SVKTASIGTLGRSRP	NEO1	1396	Q92859
RVKARGIARSPSATE	PIWIL4	6	Q7Z3Z4
LRRLGDSSGPALKRS	SEPTIN9	16	Q9UHD8
SLPTIGAETRRRKAR	SETD5	431	Q9C0A6
REGGSIPKVLRSSVR	SETD5	1176	Q9C0A6
LSPKVSERAGGRRTR	SETD6	36	Q8TBK2
LLGKRLGRSPRISSD	SAMD11	146	Q96NU1
SVKVIGAQRRRSPSA	NPAS3	126	Q8IXF0
SSLRRADPKGRSALL	WIPF3	36	A6NGB9
PSRKRDIASGAVRAL	SLC28A3	581	Q9HAS3
SPSGTILRLKGAILR	STXBP5	846	Q5T5C0
TAKRGNGLRAVTPLR	SMYD3	11	Q9H7B4
SGVGASLTRPCRKLR	STARD8	481	Q92502
QGKRPLRSSGVALSI	SEC23A	256	Q15436
VTQGKRPLRSTGVAL	SEC23B	256	Q15437
LRTVPSAKETSRGIG	RSRP1	201	Q9BUV0
SGSEGPVRLSRTRTK	ABTB2	701	Q8N961
APAEARTLSRVLKGG	ALK	116	Q9UM73
STDGKQGPIRISRSL	ADAMDEC1	191	O15204
SRGRAVRGSRVVKPE	APOL5	361	Q9BWW9
AGKRSLLISRRTGLG	SUGP1	121	Q8IWZ8
SRIVLPTEKTTGARR	DNTTIP2	151	Q5QJE6
RRIATGSFLKRNPGV	PAICS	101	P22234
RRSKTLGQSLRIVGG	TMPRSS11E	181	Q9UL52
RRPNGVITGLAARKT	FYTTD1	96	Q96QD9
VSLGELKSIRRSKPG	TBC1D17	121	Q9HA65
GGGAPVRLRSTSRKD	WDTC1	496	Q8N5D0
SEPLAGTKTRGRGRR	nan	31	Q8NFD4
PATLKTRRAKGARGL	ZNF341	296	Q9BYN7
SGRRKTRGISLGLFA	VSTM5	6	A8MXK1
ALPRKSGRAAATRSR	TTBK1	1141	Q5TCY1
VVARGKTPRVSLAGL	nan	111	P0C879
TSRARSRILRAGGKI	RPL18	106	Q07020
REPSKSLGISIVGGR	MPDZ	1156	O75970
ALSSRIGVTLRKPRG	SLC2A4RG	341	Q9NR83
LRQSTVKATGPALRR	MRPL55	11	Q7Z7F7
RSASDAGIRGTPKVR	SH3PXD2A	721	Q5TCZ1
GASVTLRTRKGLSPL	TONSL	621	Q96HA7
GLPLRVQKIRAGRST	RTCA	31	O00442
KRVGPISAVAITAGR	TNXB	1851	P22105
LSGRKRLGPISADST	TNXB	3426	P22105
RGPGLKRVTTTRLDA	TNC	791	P24821
KRSLLGARVLGPSAS	ZNF395	11	Q9H8N7
ARSVPSIRRGAEAKT	SLX9	86	Q9NSI2
SRRRESISLTPVAKG	SLC28A1	6	O00337
TTRSEPIRRAGKSGT	MAP2	1576	P11137
SLRGFLRESRKVGPG	RET	811	P07949
LVKAGAGAPRTRTVL	PIGO	766	Q8TEQ8
GAVSRTGTAPLDRLK	SLC25A23	196	Q9BV35
NTSTLRRGPGSRRKV	SH3RF2	281	Q8TEC5
STALGTPERRKGSLA	SOX5	126	P35711
GRAPRKTAGNRLSGL	VPS72	6	Q15906
SSKRALKAEGTPGRR	TMC2	36	Q8TDI7
SLAAASVALKRVGPR	ZNF831	886	Q5JPB2
AVSITGRKRSRVAPA	TKFC	341	Q3LXA3
SVKPRRTSLSRRGSI	HIVEP1	766	P15822
NSSPRTLGRSKGRLR	USP32	1396	Q8NFA0
TRGKSALLERALARP	TRAPPC5	6	Q8IUR0
GEKSRPRAGLQSLST	TTLL13	546	A6NNM8
LLRGLPGSGKTTLAR	N4BP2L1	46	Q5TBK1
LLRGLPGSGKTTLSR	N4BP2L2	406	Q92802
RVRAISRVGSSVPSK	MYOM3	446	Q5VTT5
KSSARVGLARARTRG	NAPSA	391	O96009