Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalmodulin binding

MAPKAPK5 TJP1

4.51e-0323092GO:0005516
GeneOntologyCellularComponentactin cytoskeleton

C10orf90 CARMIL1 TJP1

1.54e-0357693GO:0015629
GeneOntologyCellularComponentcentriole

TSGA10 C10orf90

2.33e-0317292GO:0005814
DomainHomeobox

ZHX2 ZHX1

5.31e-0323492PF00046
DomainHOMEOBOX_1

ZHX2 ZHX1

5.40e-0323692PS00027
DomainHOX

ZHX2 ZHX1

5.44e-0323792SM00389
DomainHomeobox_dom

ZHX2 ZHX1

5.53e-0323992IPR001356
DomainHOMEOBOX_2

ZHX2 ZHX1

5.53e-0323992PS50071
Domain-

ZHX2 ZHX1

7.68e-03283921.10.10.60
DomainHomeodomain-like

ZHX2 ZHX1

1.04e-0233292IPR009057
DomainPROTEIN_KINASE_ATP

MAPKAPK5 STYK1

1.94e-0245992PS00107
DomainProt_kinase_dom

MAPKAPK5 STYK1

2.18e-0248992IPR000719
DomainPROTEIN_KINASE_DOM

MAPKAPK5 STYK1

2.21e-0249392PS50011
DomainKinase-like_dom

MAPKAPK5 STYK1

2.64e-0254292IPR011009
Pubmed

Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.

ZHX2 ZHX1

1.79e-0739212741956
Pubmed

Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma.

ZHX2 ZHX1

1.79e-0739228152006
Pubmed

ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.

ZHX2 ZHX1

5.95e-0759217056598
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

ZHX2 ZHX1

2.20e-04879233798452
Cytoband8q24.13

ZHX2 ZHX1

2.14e-0536928q24.13
CytobandEnsembl 112 genes in cytogenetic band chr12p13

PRMT8 STYK1

2.05e-0335392chr12p13
CytobandEnsembl 112 genes in cytogenetic band chr8q24

ZHX2 ZHX1

2.07e-0335592chr8q24
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX2 ZHX1

9.62e-061562529
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX2 ZHX1

2.12e-027186228
CoexpressionGSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP

TSGA10 CARMIL1 MAPKAPK5

3.40e-0519793M6512
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRMT8 ZHX1

3.97e-0415192f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRMT8 ZHX1

4.34e-041589250df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRMT8 ZHX1

4.79e-04166923b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARMIL1 STYK1

5.02e-04170929bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARMIL1 STYK1

5.02e-04170922c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TSGA10 PRMT8

5.08e-041719252aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TSGA10 STYK1

5.20e-04173925d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C10orf90 CARMIL1

5.32e-041759221bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.75e-04182925d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.75e-04182923cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.75e-04182928a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.75e-0418292e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.88e-0418492a2191dd5546efd357b23e625beb3c5820476f243
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.94e-04185922e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.94e-0418592fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSGA10 CARMIL1

5.94e-0418592fcd95bc074e982fc7b8fd48d2e80038b9ea35ebb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.94e-0418592efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.94e-04185927aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

5.94e-0418592b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.07e-041879297e520705491c8f52a32025311a9fa7b9176979a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.07e-04187925b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

CARMIL1 TJP1

6.07e-041879277f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.07e-0418792daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.13e-041889260242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.13e-0418892505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.20e-041899242ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.20e-0418992784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.20e-041899270eea8c94fa56bb15bee8065de47acea156794e9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.20e-041899237ecbd73408d462b47d7e5611f203143e08a2689
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.26e-04190922de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.26e-0419092ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.26e-041909207f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.33e-04191922110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.33e-0419192a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.33e-04191922b056cbe2e82e056e1f798974999378460eb1d16
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C10orf90 ZHX2

6.33e-0419192f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARMIL1 TJP1

6.39e-041929235f7926628a967f85b26371e795a1b93c6f103ab
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

TJP1 STYK1

6.46e-04193924e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

C10orf90 TJP1

6.46e-04193926be11fef87af04ee7a3cc223882ccd4077caded9
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

TJP1 STYK1

6.46e-0419392518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CARMIL1 TJP1

6.53e-0419492cf7f232827945fbafd2c298c08a799ab916c2472
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

TSGA10 TJP1

6.66e-04196927be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSGA10 PRMT8

6.73e-041979274a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C10orf90 TJP1

6.87e-04199921bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C10orf90 TJP1

6.87e-04199925d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C10orf90 TJP1

6.87e-04199929dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C10orf90 TJP1

6.87e-04199926fb5f931e6217142de38c1fffc011e63bda4772b
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1|Neuronal / cells hierarchy compared to all cells using T-Statistic

C10orf90 STYK1

6.93e-0420092f75d95376a340d467c4392b872b2a2dbdd184556
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CARMIL1 TJP1

6.93e-04200927034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

C10orf90 STYK1

6.93e-042009247791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

C10orf90 STYK1

6.93e-0420092fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

C10orf90 ZHX2

6.93e-0420092e6935ad49216d2500c15c05cbc2b89402c65e838
Diseasespleen volume

MAPKAPK5 TJP1

7.42e-054392EFO_0600047
Diseaseage at assessment, pelvic organ prolapse

PRMT8 TJP1

7.42e-054392EFO_0004710, EFO_0008007

Protein segments in the cluster

PeptideGeneStartEntry
MGMKHSSRCLLLRRK

PRMT8

1

Q9NR22
HSRTIPKDMRRKIMT

MAPKAPK5

246

Q8IW41
DTCMMTPKSKRKSIH

CARMIL1

911

Q5VZK9
RCISEKEMHMRSKRI

C10orf90

641

Q96M02
RRKIMKRPSSCTHTM

STYK1

341

Q6J9G0
MASRRKSTTPCMVLA

ZHX1

1

Q9UKY1
TRLRREMMKSCKSPK

TSGA10

76

Q9BZW7
VKTMRMRLCPESRKS

TJP1

736

Q07157
MASKRKSTTPCMVRT

ZHX2

1

Q9Y6X8