Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintegrin binding

LAMB1 ADAM2 ADAM17 ADAM8 ADAM18

4.89e-06175295GO:0005178
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAM2 ADAM17 ADAM8 ADAM18

2.62e-05120294GO:0004222
GeneOntologyMolecularFunctionglycosphingolipid binding

LAMB1 LAMA1

1.57e-0413292GO:0043208
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAM2 ADAM17 ADAM8 ADAM18

1.91e-04200294GO:0008237
GeneOntologyMolecularFunctiontransition metal ion binding

NFXL1 TRIM45 ENDOU RASGRP1 ARIH1 ADAM8 ZNF330 WDFY1

2.15e-041189298GO:0046914
GeneOntologyMolecularFunctionzinc ion binding

NFXL1 TRIM45 RASGRP1 ARIH1 ADAM8 ZNF330 WDFY1

2.27e-04891297GO:0008270
GeneOntologyMolecularFunctiondiacylglycerol binding

RASGRP1 RASGRP2

2.41e-0416292GO:0019992
GeneOntologyMolecularFunctiondiacylglycerol-dependent serine/threonine kinase activity

PRKD3 PRKD1

2.41e-0416292GO:0004697
GeneOntologyMolecularFunctioncalcium ion binding

RASGRP1 CELSR3 MEGF8 ADAM8 PLA2G12A RASGRP2

6.19e-04749296GO:0005509
GeneOntologyMolecularFunctionsphingolipid binding

LAMB1 LAMA1

1.11e-0334292GO:0046625
GeneOntologyMolecularFunctioncell adhesion molecule binding

LAMB1 ADAM2 ADAM17 ADAM8 ADAM18

1.56e-03599295GO:0050839
GeneOntologyMolecularFunctionpeptidase activity

ENDOU ADAM2 ADAM17 ADAM8 ADAM18

2.29e-03654295GO:0008233
GeneOntologyMolecularFunctionglycolipid binding

LAMB1 LAMA1

2.30e-0349292GO:0051861
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMB1 LAMC2 LAMA1

2.51e-03188293GO:0005201
GeneOntologyMolecularFunctionendopeptidase activity

ADAM2 ADAM17 ADAM8 ADAM18

3.29e-03430294GO:0004175
GeneOntologyMolecularFunctionserine-type peptidase activity

ENDOU ADAM17 ADAM8

3.29e-03207293GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

ENDOU ADAM17 ADAM8

3.52e-03212293GO:0017171
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RASGRP1 ARHGEF28 RASGRP2

4.47e-03231293GO:0005085
GeneOntologyBiologicalProcessaxon guidance

LAMB1 LAMC2 ADAM17 CELSR3 MEGF8 LAMA1

2.40e-06285296GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LAMB1 LAMC2 ADAM17 CELSR3 MEGF8 LAMA1

2.45e-06286296GO:0097485
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

LAMB1 PRKD1 LAMA1

4.34e-0623293GO:2001044
GeneOntologyBiologicalProcessaxonogenesis

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 LAMA1

1.04e-05566297GO:0007409
GeneOntologyBiologicalProcessneuron projection morphogenesis

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 JADE2 LAMA1

1.05e-05802298GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 JADE2 LAMA1

1.22e-05819298GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 JADE2 LAMA1

1.30e-05826298GO:0048858
GeneOntologyBiologicalProcessaxon development

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 LAMA1

2.35e-05642297GO:0061564
GeneOntologyBiologicalProcesscell morphogenesis

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 ADAM8 JADE2 LAMA1

2.47e-051194299GO:0000902
GeneOntologyBiologicalProcessneuron projection development

LAMB1 LAMC2 PRKD1 ADAM17 ARHGEF28 CELSR3 MEGF8 JADE2 LAMA1

4.41e-051285299GO:0031175
GeneOntologyBiologicalProcessregulation of locomotion

LAMB1 LAMC2 PRKD1 ADAM17 EPPIN MEGF8 ADAM8 RECK LAMA1

5.68e-051327299GO:0040012
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LAMB1 LAMC2 ADAM17 ARHGEF28 CELSR3 MEGF8 LAMA1

6.23e-05748297GO:0048667
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMB1 LAMA1

1.04e-0411292GO:0110011
GeneOntologyBiologicalProcessneuron development

LAMB1 LAMC2 PRKD1 ADAM17 ARHGEF28 CELSR3 MEGF8 JADE2 LAMA1

1.21e-041463299GO:0048666
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation in thymus

RASGRP1 ADAM8

1.47e-0413292GO:0033089
GeneOntologyBiologicalProcessconstitutive heterochromatin formation

CENPV ATRX

1.47e-0413292GO:0140719
GeneOntologyBiologicalProcesscell recognition

ADAM2 CELSR3 MEGF8 ADAM18

1.62e-04198294GO:0008037
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

LAMB1 LAMA1

1.72e-0414292GO:2001046
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LAMB1 RECK LAMA1

2.21e-0484293GO:1903053
GeneOntologyBiologicalProcessregulation of cell motility

LAMB1 LAMC2 PRKD1 ADAM17 EPPIN ADAM8 RECK LAMA1

2.85e-041280298GO:2000145
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMB1 PRKD1 LAMA1

4.37e-04106293GO:0051149
GeneOntologyBiologicalProcesspositive regulation of response to external stimulus

RASGRP1 PRKD1 ADAM17 MEGF8 ADAM8 WDFY1

4.83e-04738296GO:0032103
GeneOntologyBiologicalProcesspositive regulation of locomotion

LAMB1 LAMC2 PRKD1 ADAM17 MEGF8 ADAM8

4.97e-04742296GO:0040017
GeneOntologyBiologicalProcessT cell differentiation in thymus

RASGRP1 ADAM17 ADAM8

5.41e-04114293GO:0033077
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

LAMB1 PRKD1 LAMA1

6.91e-04124293GO:0007229
GeneOntologyBiologicalProcessneuron projection fasciculation

CELSR3 MEGF8

7.05e-0428292GO:0106030
GeneOntologyBiologicalProcessaxonal fasciculation

CELSR3 MEGF8

7.05e-0428292GO:0007413
GeneOntologyBiologicalProcessRas protein signal transduction

SPRY1 RASGRP1 RASGRP2

7.58e-04128293GO:0007265
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

LAMB1 RASGRP1 PRKD1 MEGF8 ADAM8 JADE2 LAMA1

8.29e-041141297GO:0045597
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor superfamily cytokine production

RASGRP1 ADAM17 ADAM8

9.23e-04137293GO:1903557
GeneOntologyBiologicalProcessameboidal-type cell migration

CENPV PRKD1 ADAM17 MEGF8 ADAM8

1.15e-03577295GO:0001667
GeneOntologyBiologicalProcessregulation of cell migration

LAMB1 LAMC2 PRKD1 ADAM17 ADAM8 RECK LAMA1

1.18e-031211297GO:0030334
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

RASGRP1 ADAM8

1.23e-0337292GO:0033081
GeneOntologyBiologicalProcesspositive regulation of T cell migration

ADAM17 ADAM8

1.51e-0341292GO:2000406
GeneOntologyBiologicalProcessepithelial tube branching involved in lung morphogenesis

SPRY1 LAMA1

1.51e-0341292GO:0060441
GeneOntologyBiologicalProcesspositive regulation of chemotaxis

PRKD1 ADAM17 MEGF8

1.60e-03166293GO:0050921
GeneOntologyBiologicalProcessbasement membrane organization

LAMB1 LAMA1

1.66e-0343292GO:0071711
GeneOntologyBiologicalProcessmale gonad development

ADAM2 ATRX ADAM18

1.75e-03171293GO:0008584
GeneOntologyBiologicalProcessdevelopment of primary male sexual characteristics

ADAM2 ATRX ADAM18

1.78e-03172293GO:0046546
GeneOntologyBiologicalProcessextracellular matrix organization

LAMB1 ADAM8 RECK LAMA1

1.82e-03377294GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

LAMB1 ADAM8 RECK LAMA1

1.84e-03378294GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

LAMB1 ADAM8 RECK LAMA1

1.85e-03379294GO:0045229
GeneOntologyBiologicalProcessregulation of response to external stimulus

TRIM45 RASGRP1 PRKD1 ADAM17 MEGF8 ADAM8 WDFY1

1.91e-031316297GO:0032101
GeneOntologyBiologicalProcessforelimb morphogenesis

ATRX RECK

2.07e-0348292GO:0035136
GeneOntologyBiologicalProcesspositive regulation of lymphocyte migration

ADAM17 ADAM8

2.15e-0349292GO:2000403
GeneOntologyBiologicalProcessappendage morphogenesis

MEGF8 ATRX RECK

2.18e-03185293GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

MEGF8 ATRX RECK

2.18e-03185293GO:0035108
GeneOntologyBiologicalProcessbinding of sperm to zona pellucida

ADAM2 ADAM18

2.42e-0352292GO:0007339
GeneOntologyBiologicalProcesslymphocyte chemotaxis

ADAM17 ADAM8

2.52e-0353292GO:0048247
GeneOntologyBiologicalProcessmembrane protein ectodomain proteolysis

ADAM17 ADAM8

2.52e-0353292GO:0006509
GeneOntologyBiologicalProcesspositive regulation of cell migration

LAMB1 LAMC2 PRKD1 ADAM17 ADAM8

2.53e-03691295GO:0030335
GeneOntologyBiologicalProcessmale sex differentiation

ADAM2 ATRX ADAM18

2.69e-03199293GO:0046661
GeneOntologyBiologicalProcessblood vessel endothelial cell migration

PRKD1 ADAM17 ADAM8

2.69e-03199293GO:0043534
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

LAMB1 PRKD1 LAMA1

2.69e-03199293GO:0051147
GeneOntologyBiologicalProcesspositive regulation of innate immune response

RASGRP1 PRKD1 ADAM8 WDFY1

2.69e-03420294GO:0045089
GeneOntologyBiologicalProcesstube development

SPRY1 PRKD1 MEGF8 ATRX ADAM8 RECK LAMA1

2.74e-031402297GO:0035295
GeneOntologyBiologicalProcessregulation of T cell migration

ADAM17 ADAM8

2.80e-0356292GO:2000404
GeneOntologyCellularComponentlaminin complex

LAMB1 LAMC2 LAMA1

3.18e-0710303GO:0043256
GeneOntologyCellularComponentlaminin-2 complex

LAMB1 LAMC2

1.99e-062302GO:0005607
GeneOntologyCellularComponentlaminin-1 complex

LAMB1 LAMA1

5.97e-063302GO:0005606
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB1 LAMA1

2.67e-0417302GO:0098637
GeneOntologyCellularComponentbasement membrane

LAMB1 LAMC2 LAMA1

7.02e-04122303GO:0005604
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB1 LAMA1

3.24e-0359302GO:0098636
DomainEGF_LAM_2

LAMB1 LAMC2 CELSR3 MEGF8 LAMA1

8.70e-1030295PS50027
DomainEGF_LAM_1

LAMB1 LAMC2 CELSR3 MEGF8 LAMA1

8.70e-1030295PS01248
DomainLaminin_EGF

LAMB1 LAMC2 CELSR3 MEGF8 LAMA1

1.97e-0935295PF00053
DomainEGF_Lam

LAMB1 LAMC2 CELSR3 MEGF8 LAMA1

1.97e-0935295SM00180
DomainLaminin_EGF

LAMB1 LAMC2 CELSR3 MEGF8 LAMA1

3.04e-0938295IPR002049
DomainEGF_1

LAMB1 LAMC2 ADAM2 CELSR3 MEGF8 ADAM8 ADAM18 LAMA1

3.62e-09255298PS00022
DomainEGF-like_CS

LAMB1 LAMC2 ADAM17 CELSR3 MEGF8 ADAM8 ADAM18 LAMA1

4.35e-09261298IPR013032
DomainEGF_2

LAMB1 LAMC2 ADAM2 CELSR3 MEGF8 ADAM8 ADAM18 LAMA1

4.90e-09265298PS01186
Domain-

ADAM2 ADAM17 ADAM8 ADAM18

2.23e-08202944.10.70.10
DomainC1_1

PRKD3 RASGRP1 PRKD1 ARHGEF28 RASGRP2

2.48e-0857295PF00130
DomainDISIN

ADAM2 ADAM17 ADAM8 ADAM18

2.75e-0821294SM00050
DomainDisintegrin

ADAM2 ADAM17 ADAM8 ADAM18

2.75e-0821294PF00200
DomainZF_DAG_PE_1

PRKD3 RASGRP1 PRKD1 ARHGEF28 RASGRP2

4.49e-0864295PS00479
DomainZF_DAG_PE_2

PRKD3 RASGRP1 PRKD1 ARHGEF28 RASGRP2

4.49e-0864295PS50081
DomainC1

PRKD3 RASGRP1 PRKD1 ARHGEF28 RASGRP2

4.86e-0865295SM00109
DomainPE/DAG-bd

PRKD3 RASGRP1 PRKD1 ARHGEF28 RASGRP2

5.25e-0866295IPR002219
DomainEGF-like_dom

LAMB1 LAMC2 CELSR3 MEGF8 ADAM8 ADAM18 LAMA1

8.36e-08249297IPR000742
DomainPeptidase_M12B_N

ADAM2 ADAM17 ADAM8 ADAM18

3.71e-0739294IPR002870
DomainPep_M12B_propep

ADAM2 ADAM17 ADAM8 ADAM18

3.71e-0739294PF01562
DomainDISINTEGRIN_1

ADAM2 ADAM17 ADAM8 ADAM18

4.12e-0740294PS00427
DomainADAM_MEPRO

ADAM2 ADAM17 ADAM8 ADAM18

4.12e-0740294PS50215
DomainDISINTEGRIN_2

ADAM2 ADAM17 ADAM8 ADAM18

4.12e-0740294PS50214
DomainReprolysin

ADAM2 ADAM17 ADAM8 ADAM18

4.12e-0740294PF01421
DomainPeptidase_M12B

ADAM2 ADAM17 ADAM8 ADAM18

4.12e-0740294IPR001590
DomainDisintegrin_dom

ADAM2 ADAM17 ADAM8 ADAM18

4.56e-0741294IPR001762
DomainEGF

LAMB1 LAMC2 CELSR3 MEGF8 ADAM8 LAMA1

1.39e-06235296SM00181
DomainDisintegrin_CS

ADAM2 ADAM8 ADAM18

1.86e-0616293IPR018358
DomainADAM_CR

ADAM2 ADAM8 ADAM18

2.70e-0618293PF08516
DomainDAG/PE-bd

PRKD3 RASGRP1 PRKD1

4.39e-0621293IPR020454
DomainProtein_Kinase_C_mu-related

PRKD3 PRKD1

6.98e-063292IPR015727
DomainMetalloPept_cat_dom

ADAM2 ADAM17 ADAM8 ADAM18

7.18e-0681294IPR024079
Domain-

ADAM2 ADAM17 ADAM8 ADAM18

7.18e-06812943.40.390.10
DomainADAM_Cys-rich

ADAM2 ADAM8 ADAM18

9.60e-0627293IPR006586
DomainACR

ADAM2 ADAM8 ADAM18

9.60e-0627293SM00608
DomainEGF_3

ADAM2 CELSR3 MEGF8 ADAM8 ADAM18

2.80e-05235295PS50026
DomainLAMININ_IVA

LAMC2 LAMA1

6.48e-058292PS51115
DomainLaminin_B

LAMC2 LAMA1

6.48e-058292PF00052
DomainLamB

LAMC2 LAMA1

6.48e-058292SM00281
DomainLaminin_IV

LAMC2 LAMA1

6.48e-058292IPR000034
DomainGrowth_fac_rcpt_

LAMB1 LAMC2 MEGF8 LAMA1

9.45e-05156294IPR009030
DomainLAMININ_NTER

LAMB1 LAMA1

2.76e-0416292PS51117
DomainLaminin_N

LAMB1 LAMA1

2.76e-0416292PF00055
DomainLaminin_N

LAMB1 LAMA1

2.76e-0416292IPR008211
DomainLamNT

LAMB1 LAMA1

2.76e-0416292SM00136
DomainRasGEFN

RASGRP1 RASGRP2

4.35e-0420292SM00229
DomainRasGEF_N

RASGRP1 RASGRP2

4.80e-0421292PF00618
DomainRASGEF_NTER

RASGRP1 RASGRP2

5.27e-0422292PS50212
DomainRas-like_Gua-exchang_fac_N

RASGRP1 RASGRP2

5.27e-0422292IPR000651
Domain-

TRIM45 ARIH1 ATRX JADE2 WDFY1

5.79e-044492953.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM45 ARIH1 ATRX JADE2 WDFY1

6.40e-04459295IPR013083
DomainRASGEF

RASGRP1 RASGRP2

7.39e-0426292PS00720
DomainRASGEF_CAT

RASGRP1 RASGRP2

9.21e-0429292PS50009
DomainRasGEF

RASGRP1 RASGRP2

9.86e-0430292PF00617
Domain-

RASGRP1 RASGRP2

9.86e-04302921.10.840.10
DomainRas_GEF_dom

RASGRP1 RASGRP2

9.86e-0430292IPR023578
DomainRASGEF_cat_dom

RASGRP1 RASGRP2

9.86e-0430292IPR001895
DomainRasGEF

RASGRP1 RASGRP2

9.86e-0430292SM00147
DomainZnf_FYVE_PHD

ATRX JADE2 WDFY1

1.50e-03147293IPR011011
DomainZnf_RING

NFXL1 TRIM45 ARIH1 ATRX

1.53e-03326294IPR001841
DomainLAM_G_DOMAIN

CELSR3 LAMA1

1.58e-0338292PS50025
DomainLaminin_G_2

CELSR3 LAMA1

1.75e-0340292PF02210
DomainLamG

CELSR3 LAMA1

2.11e-0344292SM00282
DomainLaminin_G

CELSR3 LAMA1

3.65e-0358292IPR001791
DomainEGF_extracell

ADAM8 ADAM18

3.90e-0360292IPR013111
DomainEGF_2

ADAM8 ADAM18

3.90e-0360292PF07974
DomainZinc_finger_PHD-type_CS

NFXL1 JADE2

4.56e-0365292IPR019786
DomainPH

PRKD3 PRKD1 ARHGEF28

8.96e-03278293SM00233
DomainPH_DOMAIN

PRKD3 PRKD1 ARHGEF28

9.04e-03279293PS50003
DomainPH_domain

PRKD3 PRKD1 ARHGEF28

9.13e-03280293IPR001849
DomainGalactose-bd-like

LAMB1 LAMA1

9.31e-0394292IPR008979
PathwayPID_INTEGRIN4_PATHWAY

LAMB1 LAMC2 LAMA1

5.40e-0711223M158
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMB1 LAMC2 LAMA1

1.30e-0530223M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMB1 LAMC2 LAMA1

1.30e-0530223M27216
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMB1 LAMC2 LAMA1

1.75e-0533223M39503
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMB1 LAMC2 LAMA1

3.38e-0541223M27778
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMB1 LAMC2 LAMA1

4.79e-0546223M239
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMB1 LAMC2 ADAM17 ADAM8

5.93e-05140224M587
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMB1 LAMC2 ADAM17 ADAM8 LAMA1

8.26e-05300225M610
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMB1 LAMC2 LAMA1

1.01e-0459223M27218
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMB1 LAMC2 LAMA1

1.42e-0466223MM15925
PathwayPID_INTEGRIN1_PATHWAY

LAMB1 LAMC2 LAMA1

1.42e-0466223M18
PathwayBIOCARTA_PRION_PATHWAY

LAMB1 LAMA1

1.52e-0412222M22020
PathwayREACTOME_RAP1_SIGNALLING

RASGRP1 RASGRP2

2.41e-0415222MM15019
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY

PRKD3 PRKD1

2.41e-0415222M47816
PathwayREACTOME_SIGNALING_BY_MET

LAMB1 LAMC2 LAMA1

2.42e-0479223M27643
PathwayREACTOME_RAP1_SIGNALLING

RASGRP1 RASGRP2

2.75e-0416222M923
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMB1 LAMC2 LAMA1

2.90e-0484223M3228
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB1 LAMC2 LAMA1

2.90e-0484223M7098
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMB1 LAMC2 LAMA1

4.29e-0496223M39834
PathwayPID_INTEGRIN_A9B1_PATHWAY

ADAM2 ADAM8

6.82e-0425222M118
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

RASGRP1 RASGRP2

7.97e-0427222M12123
PathwayREACTOME_INTEGRIN_SIGNALING

RASGRP1 RASGRP2

7.97e-0427222M760
PathwayREACTOME_INTEGRIN_SIGNALING

RASGRP1 RASGRP2

8.57e-0428222MM14958
PathwayWP_CANCER_PATHWAYS

LAMB1 RASGRP1 LAMC2 RASGRP2 LAMA1

9.35e-04507225M48302
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMB1 LAMC2

9.85e-0430222MM15812
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMB1 LAMC2

9.85e-0430222M39641
PathwayPID_RAS_PATHWAY

RASGRP1 RASGRP2

9.85e-0430222M269
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

LAMB1 SPRY1 LAMC2 ADAM17 LAMA1

1.16e-03532225M27870
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

PRKD3 PRKD1

1.50e-0337222M554
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RASGRP1 RASGRP2

1.58e-0338222MM15456
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RASGRP1 RASGRP2

1.66e-0339222M10735
PathwayWP_RAS_SIGNALING

RASGRP1 PLA2G12A RASGRP2

2.81e-03184223M39764
PathwayWP_FOCAL_ADHESION

LAMB1 LAMC2 LAMA1

2.94e-03187223MM15913
PathwayREACTOME_SIGNALING_BY_EGFR

SPRY1 ADAM17

3.05e-0353222M27039
PathwayPID_CD8_TCR_PATHWAY

RASGRP1 RASGRP2

3.05e-0353222M88
PathwayKEGG_FOCAL_ADHESION

LAMB1 LAMC2 LAMA1

3.50e-03199223M7253
PathwayWP_FOCAL_ADHESION

LAMB1 LAMC2 LAMA1

3.50e-03199223M39402
PathwayPID_TCR_PATHWAY

RASGRP1 RASGRP2

4.42e-0364222M34
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMB1 LAMA1

6.18e-0376222M27219
Pubmed

Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.

LAMB1 LAMC2 LAMA1

5.78e-0953039719032
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMB1 LAMC2 LAMA1

1.16e-0863039506922
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMB1 LAMC2 LAMA1

3.23e-0883038872465
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMB1 LAMC2 LAMA1

3.23e-0883039489770
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMB1 LAMC2 LAMA1

6.92e-08103039034910
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMB1 LAMC2 LAMA1

6.92e-081030311784026
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMB1 LAMC2 LAMA1

9.51e-081130321524702
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMB1 LAMC2 LAMA1

9.51e-081130323472759
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMB1 LAMC2 LAMA1

1.27e-07123039396756
Pubmed

Laminin alpha5 chain is required for intestinal smooth muscle development.

LAMB1 LAMC2 LAMA1

2.62e-071530312921739
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMB1 LAMC2 LAMA1

2.62e-07153039264260
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMB1 LAMC2 LAMA1

2.62e-071530315895400
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMB1 LAMC2 LAMA1

3.22e-071630317601529
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMB1 LAMC2 LAMA1

4.68e-071830311311202
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMB1 LAMC2 LAMA1

4.68e-071830314730302
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMB1 LAMC2 LAMA1

6.54e-072030322911573
Pubmed

Monoclonal anti-mouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain.

LAMB1 LAMA1

7.19e-07230216631359
Pubmed

ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis.

ADAM17 ADAM8

7.19e-07230220220092
Pubmed

Laminin terminates the Netrin/DCC mediated attraction of vagal sensory axons.

LAMB1 LAMA1

7.19e-07230218418846
Pubmed

Form and function: the laminin family of heterotrimers.

LAMB1 LAMA1

7.19e-07230210842354
Pubmed

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.

LAMB1 LAMC2 ADAM17

1.32e-062530317170699
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMB1 LAMC2 LAMA1

1.49e-062630324742657
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMB1 LAMC2 LAMA1

2.08e-062930322613833
Pubmed

Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.

LAMB1 LAMA1

2.16e-0633022100263
Pubmed

Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.

LAMB1 LAMA1

2.16e-0633021907584
Pubmed

Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.

PRKD3 PRKD1

2.16e-06330226253275
Pubmed

Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.

LAMB1 LAMA1

2.16e-0633021292752
Pubmed

Expression of the protein kinase D (PKD) family during mouse embryogenesis.

PRKD3 PRKD1

2.16e-06330216377259
Pubmed

Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.

LAMB1 LAMA1

2.16e-0633027669546
Pubmed

Three-dimensional analysis of the developing pituitary gland in the mouse.

LAMB1 LAMA1

2.16e-0633029603432
Pubmed

Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters.

RASGRP1 RASGRP2

2.16e-06330212817022
Pubmed

An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.

LAMB1 LAMA1

2.16e-06330212615822
Pubmed

A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.

PRKD3 PRKD1

2.16e-06330227662904
Pubmed

Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.

PRKD3 PRKD1

2.16e-06330232747433
Pubmed

Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.

PRKD3 PRKD1

2.16e-06330226426580
Pubmed

A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation.

PRKD3 PRKD1

2.16e-06330220621130
Pubmed

Differential expression of laminin A and B chains during development of embryonic mouse organs.

LAMB1 LAMA1

2.16e-0633022088723
Pubmed

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.

PRKD3 PRKD1

2.16e-06330238419169
Pubmed

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.

LAMB1 LAMA1

4.31e-06430212820173
Pubmed

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

LAMB1 LAMA1

4.31e-0643022099832
Pubmed

A new paradigm for enzymatic control of α-cleavage and β-cleavage of the prion protein.

ADAM17 ADAM8

4.31e-06430224247244
Pubmed

Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death.

ADAM17 ADAM8

4.31e-06430214761956
Pubmed

Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.

PRKD3 PRKD1

4.31e-06430214743217
Pubmed

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation.

RASGRP1 RASGRP2

4.31e-06430215334074
Pubmed

Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.

LAMB1 ADAM17

4.31e-06430210433800
Pubmed

Role of mesenchymal nidogen for epithelial morphogenesis in vitro.

LAMB1 LAMA1

4.31e-0643027925005
Pubmed

Role of laminin terminal globular domains in basement membrane assembly.

LAMB1 LAMA1

4.31e-06430217517882
Pubmed

Laminin-1 reexpression in Alport mouse glomerular basement membranes.

LAMB1 LAMA1

4.31e-06430212631063
Pubmed

Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.

LAMB1 LAMA1

4.31e-0643029299121
Pubmed

New pUC-derived expression vectors for rapid construction of cDNA libraries.

LAMB1 LAMA1

4.31e-0643022436975
Pubmed

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.

LAMB1 LAMA1

4.31e-06430219074617
Pubmed

Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation.

LAMB1 LAMA1

4.31e-0643029885251
Pubmed

Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5.

LAMB1 LAMC2

4.31e-06430210801807
Pubmed

Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.

LAMB1 LAMA1

4.31e-0643029201115
Pubmed

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.

LAMB1 LAMA1

4.31e-0643028034675
Pubmed

Depletion of nuclear actin is a key mediator of quiescence in epithelial cells.

LAMB1 LAMA1

4.31e-06430221172822
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMB1 LAMC2 LAMA1

5.60e-064030327068110
Pubmed

The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development.

LAMB1 LAMA1

7.18e-0653021725162
Pubmed

Expression of laminin and nidogen genes during the postimplantation development of the mouse placenta.

LAMB1 LAMA1

7.18e-0653028286607
Pubmed

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

RASGRP1 RASGRP2

7.18e-0653029789079
Pubmed

Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo.

LAMB1 LAMA1

7.18e-0653028359228
Pubmed

Expression of collagen alpha 1(IV), laminin and nidogen genes in the embryonic mouse lung: implications for branching morphogenesis.

LAMB1 LAMA1

7.18e-0653027516699
Pubmed

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

LAMB1 LAMA1

7.18e-06530219416897
Pubmed

Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.

RASGRP1 RASGRP2

7.18e-06530218172297
Pubmed

Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.

LAMB1 LAMA1

7.18e-06530210964500
Pubmed

The laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LAR.

LAMB1 LAMA1

7.18e-0653029647658
Pubmed

Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.

LAMB1 LAMA1

7.18e-0653028613743
Pubmed

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.

LAMB1 LAMA1

7.18e-0653027544312
Pubmed

Laminin-10 is crucial for hair morphogenesis.

LAMB1 LAMA1

7.18e-06530212743034
Pubmed

Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart.

LAMB1 LAMA1

7.18e-0653027851641
Pubmed

Localization of the 110 kDa receptor for laminin in brains of embryonic and postnatal mice.

LAMB1 LAMA1

7.18e-0653027895274
Pubmed

Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.

LAMB1 LAMA1

7.18e-0653028719886
Pubmed

Protein kinase D regulates RhoA activity via rhotekin phosphorylation.

PRKD3 PRKD1

7.18e-06530222228765
Pubmed

Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.

LAMB1 LAMA1

1.08e-0563021678389
Pubmed

Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.

LAMB1 LAMA1

1.08e-05630223948589
Pubmed

Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.

LAMB1 LAMA1

1.08e-05630219118221
Pubmed

Entactin: structure and function.

LAMB1 LAMA1

1.08e-0563022119632
Pubmed

Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12.

LAMB1 ADAM17

1.08e-0563029598327
Pubmed

Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression.

LAMB1 LAMA1

1.08e-05630218162078
Pubmed

Expression and role of laminin-1 in mouse pancreatic organogenesis.

LAMB1 LAMA1

1.08e-05630210866045
Pubmed

Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.

LAMB1 LAMA1

1.08e-05630226555376
Pubmed

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.

ADAM17 RASGRP2

1.08e-05630229925524
Pubmed

Effect of basement membrane entactin on epidermal cell attachment and growth.

LAMB1 LAMA1

1.08e-0563023794389
Pubmed

Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.

ADAM17 ADAM8

1.08e-05630219574220
Pubmed

Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.

LAMB1 LAMA1

1.08e-05630220874775
Pubmed

Laminin-nidogen complex. Extraction with chelating agents and structural characterization.

LAMB1 LAMA1

1.08e-0563023109910
Pubmed

Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.

LAMB1 LAMA1

1.51e-0573028276400
Pubmed

A new nomenclature for the laminins.

LAMB1 LAMC2

1.51e-0573027921537
Pubmed

Laminin isoforms in fetal and adult human adrenal cortex.

LAMB1 LAMA1

1.51e-05730214557481
Pubmed

Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.

ADAM17 ADAM8

1.51e-05730215907280
Pubmed

Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.

LAMB1 LAMA1

1.51e-0573029390664
Pubmed

Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions.

RASGRP1 RASGRP2

1.51e-05730216076873
Pubmed

Differential expression of laminin chain-specific mRNA transcripts during mouse preimplantation embryo development.

LAMB1 LAMA1

1.51e-0573028722691
Pubmed

Site-specific expression of gelatinolytic activity during morphogenesis of the secondary palate in the mouse embryo.

LAMB1 LAMA1

2.01e-05830223091646
Pubmed

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.

LAMB1 LAMA1

2.01e-05830212015298
Pubmed

Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.

LAMB1 LAMC2

2.01e-0583027898049
Pubmed

Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice.

LAMB1 LAMA1

2.01e-0583028812145
Pubmed

Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis.

LAMB1 LAMA1

2.01e-0583028725284
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMB1 LAMC2

2.01e-05830223529140
Pubmed

Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.

ADAM17 ADAM8

2.01e-05830217344430
InteractionADAM12 interactions

SPRY1 ADAM2 ADAM8 RECK

1.39e-0658294int:ADAM12
InteractionFBXO2 interactions

LAMB1 LAMC2 ADAM17 CELSR3 MEGF8 LAMA1

2.21e-05411296int:FBXO2
InteractionPSG8 interactions

LAMB1 CELSR3 MEGF8

2.75e-0541293int:PSG8
CytobandEnsembl 112 genes in cytogenetic band chr2q36

SCYGR8 WDFY1

1.42e-0385302chr2q36
CytobandEnsembl 112 genes in cytogenetic band chr8p11

ADAM2 ADAM18

2.08e-03103302chr8p11
CytobandEnsembl 112 genes in cytogenetic band chr14q12

PRKD1 IPO4

2.16e-03105302chr14q12
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM2 ADAM17 ADAM8 ADAM18

2.32e-082721447
GeneFamilyLaminin subunits

LAMB1 LAMC2 LAMA1

2.95e-0712213626
CoexpressionGSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP

PRKD3 LAMB1 CENPV ATRX RECK

2.52e-06200295M3425
CoexpressionNABA_MATRISOME

LAMB1 LAMC2 ADAM2 ADAM17 MEGF8 ADAM8 ADAM18 LAMA1

9.72e-061008298MM17056
CoexpressionNABA_MATRISOME

LAMB1 LAMC2 ADAM2 ADAM17 MEGF8 ADAM8 ADAM18 LAMA1

1.11e-051026298M5889
CoexpressionNABA_BASEMENT_MEMBRANES

LAMB1 LAMC2 LAMA1

1.17e-0540293M5887
CoexpressionHOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP

LAMB1 RASGRP1 ATRX

4.41e-0562293M6176
CoexpressionWEBER_METHYLATED_ICP_IN_SPERM_DN

ADAM2 ADAM18

9.15e-0513292M16399
CoexpressionNABA_ECM_REGULATORS

ADAM2 ADAM17 ADAM8 ADAM18

1.32e-04238294M3468
CoexpressionNABA_ECM_REGULATORS

ADAM2 ADAM17 ADAM8 ADAM18

1.40e-04242294MM17062
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

PRKD3 LAMB1 LAMC2 ATRX RASGRP2

1.70e-04482295M12144
CoexpressionQI_PLASMACYTOMA_DN

LAMB1 LAMC2 IPO4

1.73e-0498293M1852
CoexpressionQI_PLASMACYTOMA_DN

LAMB1 LAMC2 IPO4

1.83e-04100293MM775
ToppCellE12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 LAMC2 ARHGEF28 PLA2G12A

5.81e-06183294031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

RASGRP1 ARIH1 ATRX ADAM8

7.62e-061962947bced0cc2112697593c478fa291b8ed3941fb811
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LAMB1 SPRY1 PRKD1 LAMA1

8.25e-06200294a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NFXL1 RASGRP1 JADE2

1.15e-04146293159dd157a74f3c27dc1a1dcbbf0ed8f9462cac9e
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR3 ADAM8 ADAM18

1.25e-041502936e806a028c0519489151c181d9907e05289e27e0
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM2 CELSR3 ADAM18

1.56e-041622939f568836199a05f696294caac1ea3fa413984423
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SPRY1 LAMA1

1.71e-041672933e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SPRY1 LAMA1

1.71e-041672933ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 LAMC2 LAMA1

1.86e-041722930c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 LAMC2 LAMA1

1.86e-04172293eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRP1 PRKD1 ARHGEF28

2.00e-041762930710689e66deba179b0a8038cdd56b4834984f12
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 SPRY1 PRKD1

2.03e-0417729396d639407f79669f3990138793d157b94273581c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRP1 PRKD1 ARHGEF28

2.03e-04177293921783ed0fe20294d2f384d9136924b679df01bb
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRP1 PRKD1 ARHGEF28

2.06e-041782936f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.10e-0417929356db12467b445f2b8ef92af50779eeab10413eb2
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

PRKD3 WDFY1 LAMA1

2.17e-041812939d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 RASGRP1 ARHGEF28

2.20e-04182293cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCellE12.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 LAMC2 PLA2G12A

2.20e-04182293204530444e35d4977a7239ac176f477e9e5c29ab
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

LAMB1 ADAM17 ARHGEF28

2.31e-0418529385cb81759589a26d83676cffbf2bc37399683c10
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 ENDOU PRKD1

2.35e-04186293e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB1 RECK RASGRP2

2.35e-04186293db9b67066fc003c7995ec205d15176bf40c97add
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 PRKD1 LAMA1

2.35e-04186293f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 PRKD1 LAMA1

2.38e-04187293c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellE12.5-Epithelial-epithelial_progenitor_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 LAMC2 ARHGEF28

2.38e-04187293ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 RECK LAMA1

2.38e-04187293e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 RECK LAMA1

2.38e-04187293b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 RECK LAMA1

2.38e-041872939fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 PRKD1 LAMA1

2.42e-04188293af740fa78542438fdff627ea1f74f4eee43316be
ToppCellwk_08-11-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 ADAM8 RASGRP2

2.42e-04188293a8170e4ce6406af9f5ad5317e6e26efa7bc66411
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPV ARHGEF28 CELSR3

2.46e-041892933f5522be3e24dcdb6272f18cee2f239dfdeff9ad
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 PRKD1 LAMA1

2.46e-04189293830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellControl-Myeloid-Macrophage_Alveolar|Control / Disease state, Lineage and Cell class

LAMB1 ADAM17 ARHGEF28

2.46e-04189293937e876122bc4b94372a4104e9c1a9068c232018
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.46e-04189293ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellwk_08-11-Hematologic_Lymphocytic-NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 ADAM8 RASGRP2

2.50e-0419029386b0d142b7d1a3b35580edd104f947106be2c9c6
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMB1 SPRY1 LAMC2

2.50e-0419029312992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

LAMB1 ADAM17 ARHGEF28

2.50e-041902939fc763d65470ba8858b973689c4d4358faab7dd3
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.50e-041902937e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB1 RECK RASGRP2

2.50e-04190293979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.50e-041902931004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCell18-Airway-Immune-Immune|Airway / Age, Tissue, Lineage and Cell class

RASGRP1 ADAM8 RASGRP2

2.50e-0419029309e6bbe4f1be48153dc6cd647a57a0b531b8bf99
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMB1 SPRY1 ARHGEF28

2.50e-0419029306bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.50e-041902937fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.50e-0419029310b02c62e72bfea9767e3e751011436925da823e
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB1 SPRY1 PRKD1

2.50e-04190293d60395739458d7f47a3350ade751fe3819500320
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 LAMC2 PLA2G12A

2.54e-041912936f5d91a9583bbb30dfaa30dd9c7772995a9196be
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

LAMB1 SPRY1 ARHGEF28

2.54e-0419129305867b96199a46a415848409130697c810d18937
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRKD1 ARHGEF28 LAMA1

2.54e-04191293fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMB1 SPRY1 ARHGEF28

2.54e-041912934c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 PRKD1 LAMA1

2.54e-04191293d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

LAMB1 ADAM17 ARHGEF28

2.54e-04191293a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMB1 SPRY1 ARHGEF28

2.54e-04191293de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMB1 SPRY1 ARHGEF28

2.54e-041912932b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LAMB1 SPRY1 ARHGEF28

2.54e-0419129302e1ae144da7274171e055356d10e8d175c5347f
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRKD1 ARHGEF28 LAMA1

2.54e-041912930965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6|TCGA-Stomach / Sample_Type by Project: Shred V9

LAMC2 ADAM8 WDFY1

2.58e-041922934e689bca7a242f8482e25f273656e2caba8821c0
ToppCellE15.5-Epithelial-epithelial_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 LAMC2 PLA2G12A

2.58e-04192293cb6f42dcffe650f7958543531d8f5412b2f2eb12
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB1 RECK RASGRP2

2.58e-04192293063e119c4b58957643908f667e6cfd6f7517fd03
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.58e-04192293158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMC2 ARHGEF28 LAMA1

2.58e-0419229339804d9ddc67c1b41887752df2503389eae44a1a
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMB1 SPRY1 ARHGEF28

2.58e-0419229334505a13b8a47c9286c560122fa7861b9c331a08
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMB1 SPRY1 ARHGEF28

2.58e-0419229357c1410ebf90c230993e065eb78385daa3360960
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.58e-04192293f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPV ARHGEF28 CELSR3

2.66e-041942935bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SPRY1 LAMA1

2.66e-04194293415801a3dfacf05f2b603fb424df3d045190a812
ToppCellCOVID-19-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

LAMB1 SPRY1 ARHGEF28

2.66e-041942934060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC2 PRKD1 ARHGEF28

2.66e-04194293e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 ARHGEF28 LAMA1

2.66e-0419429393c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellCOVID-19-lung-NK_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

RASGRP1 ADAM8 RASGRP2

2.66e-041942934c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SPRY1 LAMA1

2.66e-04194293256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SPRY1 LAMA1

2.66e-041942937942bc83c1bdca687795b91aa232824d603f9b09
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.70e-041952937a32a8535c29b819dacba901d0658280a2631c94
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 RECK RASGRP2

2.70e-041952934a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

RASGRP1 ATRX ADAM8

2.70e-041952932b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellCOVID-19-lung-NK_cells|lung / Disease (COVID-19 only), tissue and cell type

RASGRP1 ADAM8 RASGRP2

2.70e-041952933b716ec7acc9a37af6bf40e711a539ce58d74aa4
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 LAMC2 LAMA1

2.74e-04196293a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 ARHGEF28 LAMA1

2.74e-041962936ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 ARHGEF28 LAMA1

2.74e-04196293eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMC2 ARHGEF28 LAMA1

2.74e-041962930a34a0009f479384f1994c6f977f942699a132c8
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 LAMC2 LAMA1

2.78e-04197293f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellMild|World / Condition, Lineage, Cell class and cell subclass

LAMB1 ATRX JADE2

2.78e-04197293476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMB1 SPRY1 ARHGEF28

2.86e-041992931c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.86e-04199293dfb89ff7b075420c63ead0f802d93a5f82fb7c28
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMB1 PRKD1 RECK

2.86e-0419929330d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_CTL|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.86e-041992937c63c389c914f1ef2fa92fa153f9ecf1087b8e31
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LAMB1 SPRY1 ATRX

2.86e-04199293615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-04200293993b0856964d611af8d8cd1ea4d609fa3ede65ea
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LAMB1 PRKD1 LAMA1

2.90e-042002939b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellNeuronal-Excitatory-eF(C1QL3)|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRP1 PRKD1 ARHGEF28

2.90e-042002937668ae7ed550583ab59e419c5c9bb9f2d7e8e0d5
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3-NKT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-04200293846d3f0e647040d0e372df0dfcd69a21d5da5aea
ToppCellNeuronal-Excitatory-eF(C1QL3)----L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRP1 PRKD1 ARHGEF28

2.90e-0420029344f0278cb0e4ffcda4af3719d7f5819a10929b9f
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

LAMB1 RASGRP1 CELSR3

2.90e-0420029310882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-042002932efea0f2ac28d973182763d7667614204718d624
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-04200293c70f06b243ae9804f97308ee02b4b5e1a4a6f9f3
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3-NKT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-04200293e9e1bd27d0ac3619c3a09e168a886cfd20e874b2
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD3|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-0420029306bd16ce6592e5afb8c2741687d98482faa55f4d
ToppCellNeuronal-Excitatory-eF(C1QL3)---|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRP1 PRKD1 ARHGEF28

2.90e-0420029323da7790e09575b2ca909ed16806b44223bf1017
ToppCellNeuronal-Excitatory-eF(C1QL3)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRP1 PRKD1 ARHGEF28

2.90e-0420029391f3df1c5a661ff703835f58a35cee93f18eb15c
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_CTL|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP1 ADAM8 RASGRP2

2.90e-04200293641c875ab1403e02d5d47a6f645d27273c2ee056
ToppCellNeuronal-Excitatory-eF(C1QL3)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRP1 PRKD1 ARHGEF28

2.90e-042002932e2b1d252972b702ade25526ec8461bf613d81b0
ComputationalGenes in the cancer module 493.

LAMB1 ATRX JADE2

1.61e-0469173MODULE_493
DrugAC1L1B58

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

2.71e-1029295CID000001288
DrugH-9 dihydrochloride

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

9.50e-0890295CID000003544
Drugpioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A

TRIM45 SPRY1 ARHGEF28 ATRX ZNF330 RECK

1.01e-071832967088_DN
DrugAC1L1G72

LAMB1 LAMC2 LAMA1

3.04e-0711293CID000003553
DrugI-Q-S

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

1.47e-06156295CID000003540
DrugSikvav

LAMB1 LAMC2 LAMA1

3.69e-0624293CID005487517
DrugMegestrol acetate [595-33-5]; Down 200; 10.4uM; PC3; HT_HG-U133A

LAMC2 ARHGEF28 CELSR3 MEGF8 ADAM8

4.29e-061942956667_DN
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

LAMB1 ARHGEF28 CELSR3 JADE2 RASGRP2

4.62e-061972957500_UP
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A

LAMB1 SPRY1 ARHGEF28 MEGF8 ADAM8

4.98e-062002955917_DN
DrugPDBu

PRKD3 RASGRP1 PRKD1 CELSR3 RASGRP2

1.44e-05249295CID000037783
DrugCalcort

LAMB1 LAMC2 LAMA1

1.52e-0538293CID000026709
DrugIkvav

LAMB1 LAMC2 LAMA1

1.52e-0538293CID000131343
Drug1-stearoyl-2-arachidonoyl-sn-glycerol

PRKD3 RASGRP1 PRKD1

1.78e-0540293CID000001398
Drug1-(5-isoquinolinesulfonyl)-2-methylpiperazine

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

4.37e-05314295CID000003542
Drugkalinin

LAMB1 LAMC2 LAMA1

4.66e-0555293CID000032518
DrugCC270

LAMB1 LAMC2 LAMA1

5.76e-0559293CID006918852
DrugLG 5

LAMB1 LAMC2 LAMA1

6.05e-0560293CID011840957
DrugDB04780

PRKD3 LAMB1 LAMC2 PRKD1

6.16e-05170294CID005459389
Drugtaxol

PRKD3 LAMB1 LAMC2 PRKD1 ARIH1 LAMA1

6.32e-05560296CID000004666
DrugAC1L1ET5

PRKD3 PRKD1 LAMA1

7.70e-0565293CID000002936
DrugBM165

LAMB1 LAMC2

8.55e-0511292CID003352881
Drug5152487; Up 200; 10uM; MCF7; HT_HG-U133A_EA

PRKD3 ADAM2 CELSR3 JADE2

1.01e-04193294896_UP
Drug5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA

ADAM2 CELSR3 ADAM8 RASGRP2

1.03e-04194294828_UP
DrugC-1b

PRKD3 RASGRP1 PRKD1

1.04e-0472293CID006102740
DrugMethazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A

PRKD3 LAMC2 ADAM8 ZNF330

1.05e-041952946268_UP
DrugSolanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A

PRKD3 TRIM45 JADE2 ZNF330

1.05e-041952942808_DN
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; MCF7; HT_HG-U133A

PRKD3 LAMC2 ARHGEF28 ADAM8

1.07e-041962946469_DN
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A

PRKD3 LAMC2 MEGF8 ADAM8

1.09e-041972943382_UP
DrugMilrinone [78415-72-2]; Down 200; 19uM; PC3; HT_HG-U133A

ATRX ADAM8 ZNF330 RECK

1.13e-041992945856_DN
DrugIsoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A

PRKD3 ADAM17 ATRX JADE2

1.13e-041992943451_UP
DrugEthamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A

LAMC2 PRKD1 ADAM8 RASGRP2

1.13e-041992944399_UP
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

LAMC2 ADAM17 ARHGEF28 MEGF8

1.13e-041992946674_DN
Drughaloperidol; Up 200; 10uM; MCF7; HT_HG-U133A

SPRY1 ARHGEF28 MEGF8 RASGRP2

1.13e-041992945604_UP
Drugdysprosium

LAMB1 LAMC2 LAMA1

1.13e-0474293CID000023912
DrugA0395

LAMB1 LAMC2 ADAM17

1.18e-0475293CID009906466
DrugMS-551

ARIH1 ADAM8

1.21e-0413292CID000004486
Drug2-amino-5-methylpyridine

LAMB1 LAMC2 LAMA1

1.28e-0477293CID000015348
DrugYIGSR

LAMB1 LAMC2 LAMA1

1.38e-0479293CID000123977
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMB1 LAMC2 LAMA1

1.59e-0483293CID011968896
Drugdansyl-DAG

PRKD3 PRKD1

1.63e-0415292CID000129493
DrugRK-1409B

PRKD3 PRKD1

1.63e-0415292CID003036125
Drug1-stearoyl-2-arachidonylglycerol

PRKD3 PRKD1

1.63e-0415292CID006443869
DrugNSC 714187

LAMB1 LAMC2 LAMA1

1.71e-0485293CID005288693
Drug1,2-dimethylhydrazine

LAMB1 LAMC2 LAMA1

1.77e-0486293CID000001322
Drug5-hydroxydecanoate

PRKD3 PRKD1 ARIH1

1.83e-0487293CID000001824
DrugC-1A

PRKD3 RASGRP1 PRKD1

2.09e-0491293CID009543473
DrugAC1L1JQC

PRKD3 PRKD1

2.11e-0417292CID000005157
Drugdaphnoretin

PRKD3 PRKD1

2.11e-0417292CID005281406
Drugdipalmitin

PRKD3 PRKD1

2.37e-0418292CID000068149
DrugCgp-42700

PRKD3 PRKD1

2.37e-0418292CID000188390
Drugdihydrosterculic acid

PRKD3 PRKD1

2.37e-0418292CID000160788
DrugTAPP-Br

PRKD3 PRKD1

2.64e-0419292CID000160326
Drugsapintoxin A

PRKD3 PRKD1

2.64e-0419292CID000108085
DrugAC1L1KMJ

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

3.07e-04476295CID000030956
DrugKS-619-1

PRKD3 PRKD1

3.24e-0421292CID000128369
DrugK-259-2

PRKD3 PRKD1

3.24e-0421292CID006438946
Drugdebromoaplysiatoxin

PRKD3 PRKD1

3.24e-0421292CID000002967
Drugbroussochalcone A

PRKD3 PRKD1

3.24e-0421292CID006438825
DrugALT-711

LAMB1 LAMC2

3.24e-0421292CID000216304
DrugMDL 27,032

PRKD3 PRKD1

3.24e-0421292CID000163812
DrugAC1L1C2F

LAMB1 LAMC2 LAMA1

3.66e-04110293CID000001711
DrugAC1L4NFY

PRKD3 PRKD1

3.90e-0423292CID000160335
Drugcholesterol sulfate

PRKD3 LAMC2 PRKD1

3.96e-04113293CID000065076
Druggenistein

PRKD3 LAMB1 CENPV LAMC2 PRKD1 ADAM17 LAMA1

4.05e-041117297CID005280961
Drugmethazolamide

CELSR3 KIN

5.00e-0426292CID000004100
Drugbeta-tocopherol

PRKD3 PRKD1

5.39e-0427292CID000008989
Drugilmofosine

PRKD3 PRKD1

5.39e-0427292CID000055008
DrugC15720

PRKD3 PRKD1

5.39e-0427292CID000003979
Drugpseudohypericin

PRKD3 PRKD1

5.39e-0427292CID005281751
Drugnickel chloride

SPRY1 ENDOU LAMC2 ADAM17 PLA2G12A ZNF330 RECK

5.57e-041178297ctd:C022838
DrugAC1L1JM9

PRKD3 RASGRP1 PRKD1 ADAM17

5.69e-04304294CID000005103
Drugbisindolylmaleimide II

PRKD3 PRKD1

5.80e-0428292CID000002397
Drugbisindolylmaleimide V

PRKD3 PRKD1

5.80e-0428292CID000002400
Drugaplysiatoxin

PRKD3 PRKD1

5.80e-0428292CID000040465
DrugHBDDE

PRKD3 PRKD1

5.80e-0428292CID000003568
DrugSC-10

PRKD3 PRKD1

5.80e-0428292CID000005175
DrugNCDC

PRKD3 PRKD1

5.80e-0428292CID000001583
Drug2,3-pentanedione

RASGRP1 LAMC2 ADAM8

5.83e-04129293ctd:C013186
DrugAC1Q6DXY

PRKD3 PRKD1

6.23e-0429292CID000003719
DrugPolychlorinated biphenyls

PRKD3 PRKD1

6.23e-0429292CID000006636
DrugAC1L40MO

PRKD3 PRKD1 ADAM17

6.37e-04133293CID000099067
DrugNSC339555

PRKD3 RASGRP1 PRKD1

6.37e-04133293CID000433902
Drugdibutyryl cyclic 3',5'-AMP

PRKD3 LAMB1 LAMC2 PRKD1 LAMA1

6.49e-04561295CID000002460
DrugAC1Q5V5T

PRKD3 CENPV PRKD1

6.65e-04135293CID000004701
Druggepirone

PRKD3 PRKD1

6.67e-0430292CID000055190
DrugGf 109

PRKD3 PRKD1

6.67e-0430292CID000196144
DrugAC1L3G0K

PRKD3 PRKD1

6.67e-0430292CID000114822
Drug12-deoxyphorbol 13-phenylacetate

PRKD3 PRKD1

6.67e-0430292CID000105100
DrugN,n,n-tms

PRKD3 PRKD1

7.12e-0431292CID006439410
Drugtrypanothione disulfide

LAMB1 LAMC2 ADAM8

7.40e-04140293CID000115098
Drug0-to

PRKD3 PRKD1 ADAM17

7.55e-04141293CID000002051
DrugAC1L1E8B

PRKD1 ADAM17

7.59e-0432292CID000002684
Drugisovalerate

ENDOU ADAM17 LAMA1

7.86e-04143293CID000010430
DrugCGS 9343B

PRKD3 PRKD1

8.07e-0433292CID000065909
DrugArgentine

ADAM2 LAMA1

8.07e-0433292CID000442941
Drugnaphthalenesulfonamide

PRKD3 PRKD1

8.07e-0433292CID000163571
DrugAC1L1FGW

PRKD3 PRKD1

8.07e-0433292CID000003231
DrugDiC8

PRKD3 RASGRP1 PRKD1

8.35e-04146293CID000001323
DrugAC1NSKHR

PRKD3 PRKD1

8.57e-0434292CID005311362
Drugh x mg

PRKD3 PRKD1

8.57e-0434292CID000001380
DiseaseGlioblastoma Multiforme

PRKD3 ATRX RECK

1.42e-04111273C1621958
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

ADAM17 ADAM18

1.68e-0421272EFO_0000180, Orphanet_391311
Diseaselung small cell carcinoma (is_implicated_in)

LAMC2 ATRX

3.00e-0428272DOID:5409 (is_implicated_in)
Diseaselung squamous cell carcinoma (is_marker_for)

LAMC2 ATRX

4.98e-0436272DOID:3907 (is_marker_for)
Diseasecandidiasis (implicated_via_orthology)

PRKD3 PRKD1

7.45e-0444272DOID:1508 (implicated_via_orthology)
Diseasevisceral:subcutaneous adipose tissue ratio

ADAM17 ADAM18

1.87e-0370272EFO_0004767
Diseasesusceptibility to mumps measurement

ADAM17 ADAM18

2.15e-0375272EFO_0008404
Diseaseacne

SPRY1 LAMC2

5.83e-03125272EFO_0003894

Protein segments in the cluster

PeptideGeneStartEntry
CNDRGVCNNKKHCHC

ADAM2

621

Q99965
NEECDCGNKNECQFK

ADAM18

401

Q9Y3Q7
RCKDCGMNCHKQCKD

RASGRP1

571

O95267
AQCAHGTCCQECKVK

ADAM8

446

P78325
CCDRAEDHACQNACK

RECK

216

O95980
CQKQCRDENGFKCHC

KIN

31

O60870
CSNCNANVHKGCKDA

ARHGEF28

681

Q8N1W1
RCKCGRQFCFNCGEN

ARIH1

296

Q9Y4X5
CCNQHDRCYETCGKS

PLA2G12A

106

Q9BZM1
CKDCRFNCHKRCAPK

PRKD1

301

Q15139
CQKHQCRRKCCPGNC

NFXL1

476

Q6ZNB6
GLKCRACGVNCHKQC

RASGRP2

526

Q7LDG7
MVFCDKCNVCVHQAC

JADE2

216

Q9NQC1
CNARCQEFGNCCKDF

ENDOU

106

P21128
KCTKCQCNGHADTCN

MEGF8

2376

Q7Z7M0
QCKDCKFNCHKRCAS

PRKD3

301

O94806
GRNSNACKKCNCNEH

LAMB1

326

P07942
CCDFCHNAFCKKCIL

ATRX

231

P46100
DCNCSICKKKQNRHF

CENPV

171

Q7Z7K6
CNDNTDGIHCEKCKN

LAMC2

56

Q13753
NCNKTNGQCHCKEFH

CELSR3

2051

Q9NYQ7
LGQFCCALHKACQSC

IPO4

721

Q8TEX9
DRQCQDNKKCCVFSC

EPPIN

51

O95925
RCQTCKANLCHFCCQ

TRIM45

146

Q9H8W5
GNTCEACNCHNKAKD

LAMA1

321

P25391
QQKGCCQQKCCCQKQ

SCYGR8

91

A0A286YFG1
CCKNCQFETAQKKCQ

ADAM17

521

P78536
QHKFICEQCGKCKCG

SPRY1

176

O43609
LGQHSCLRCKACFCD

ZNF330

181

Q9Y3S2
QHHCRKCGQAVCGKC

WDFY1

311

Q8IWB7