Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of opsonization	COLEC10 COLEC11 FCN2	1.24e-05	9	111	3	GO:1903028
GeneOntologyBiologicalProcess	negative regulation of neurotransmitter secretion	ASIC1 NF1 PRKN	1.24e-05	9	111	3	GO:0046929
GeneOntologyBiologicalProcess	regulation of opsonization	COLEC10 COLEC11 FCN2	2.43e-05	11	111	3	GO:1903027
GeneOntologyBiologicalProcess	complement activation, lectin pathway	COLEC10 COLEC11 FCN2	3.22e-05	12	111	3	GO:0001867
GeneOntologyBiologicalProcess	negative regulation of neurotransmitter transport	ASIC1 NF1 PRKN	5.29e-05	14	111	3	GO:0051589
GeneOntologyCellularComponent	cell surface	MRC1 VLDLR GFRAL ASIC1 HCN1 ADAM30 COLEC10 ELSPBP1 IZUMO1R VWDE COLEC11 CD4 CSF2RB FCN2 CD163L1 DNAI2 BTN2A3P CLEC4C NOTCH2 NOTCH3	2.23e-06	1111	114	20	GO:0009986
GeneOntologyCellularComponent	external side of plasma membrane	GFRAL ADAM30 COLEC10 IZUMO1R COLEC11 CD4 CSF2RB FCN2 CD163L1 DNAI2 BTN2A3P CLEC4C	2.69e-05	519	114	12	GO:0009897
GeneOntologyCellularComponent	serine-type endopeptidase complex	COLEC10 COLEC11 FCN2	1.68e-04	20	114	3	GO:1905370
GeneOntologyCellularComponent	serine-type peptidase complex	COLEC10 COLEC11 FCN2	2.26e-04	22	114	3	GO:1905286
GeneOntologyCellularComponent	axonemal dynein complex	DNAH2 DNAH1 DNAI2	3.33e-04	25	114	3	GO:0005858
Domain	Notch_dom	PAPPA NOTCH2 NOTCH3	7.22e-06	7	112	3	IPR000800
Domain	Notch	PAPPA NOTCH2 NOTCH3	7.22e-06	7	112	3	PF00066
Domain	NL	PAPPA NOTCH2 NOTCH3	7.22e-06	7	112	3	SM00004
Domain	PP2Ac	PPEF2 PPP4C PPP3CB	5.75e-05	13	112	3	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPEF2 PPP4C PPP3CB	5.75e-05	13	112	3	IPR006186
Domain	SER_THR_PHOSPHATASE	PPEF2 PPP4C PPP3CB	5.75e-05	13	112	3	PS00125
Domain	DUF3454	NOTCH2 NOTCH3	1.07e-04	3	112	2	PF11936
Domain	DUF3454_notch	NOTCH2 NOTCH3	1.07e-04	3	112	2	IPR024600
Domain	DUF3454	NOTCH2 NOTCH3	1.07e-04	3	112	2	SM01334
Domain	C-type_lectin_CS	MRC1 COLEC10 COLEC11 CLEC4C	1.26e-04	43	112	4	IPR018378
Domain	Notch	NOTCH2 NOTCH3	2.12e-04	4	112	2	IPR008297
Domain	NODP	NOTCH2 NOTCH3	2.12e-04	4	112	2	PF07684
Domain	Notch_NODP_dom	NOTCH2 NOTCH3	2.12e-04	4	112	2	IPR011656
Domain	Dpy19	DPY19L2 DPY19L1	2.12e-04	4	112	2	PF10034
Domain	Dpy-19/Dpy-19-like	DPY19L2 DPY19L1	2.12e-04	4	112	2	IPR018732
Domain	Notch_NOD_dom	NOTCH2 NOTCH3	2.12e-04	4	112	2	IPR010660
Domain	NOD	NOTCH2 NOTCH3	2.12e-04	4	112	2	PF06816
Domain	NOD	NOTCH2 NOTCH3	2.12e-04	4	112	2	SM01338
Domain	NODP	NOTCH2 NOTCH3	2.12e-04	4	112	2	SM01339
Domain	Quinoprotein_ADH-like_supfam	DMXL2 ERN1 WDR7 WDR72	2.86e-04	53	112	4	IPR011047
Domain	SLED	SFMBT1 SFMBT2	3.52e-04	5	112	2	IPR021987
Domain	SLED	SFMBT1 SFMBT2	3.52e-04	5	112	2	PF12140
Domain	LNR	NOTCH2 NOTCH3	3.52e-04	5	112	2	PS50258
Domain	Metallophos	PPEF2 PPP4C PPP3CB	6.17e-04	28	112	3	PF00149
Domain	Calcineurin-like_PHP_ApaH	PPEF2 PPP4C PPP3CB	6.17e-04	28	112	3	IPR004843
Domain	Metallo-depent_PP-like	PPEF2 PPP4C PPP3CB	7.57e-04	30	112	3	IPR029052
Domain	-	PPEF2 PPP4C PPP3CB	7.57e-04	30	112	3	3.60.21.10
Domain	Kringle-like	MRC1 ELSPBP1 SLC22A8	9.17e-04	32	112	3	IPR013806
Domain	MBT	SFMBT1 SFMBT2	1.25e-03	9	112	2	SM00561
Domain	MBT	SFMBT1 SFMBT2	1.25e-03	9	112	2	PS51079
Domain	C_TYPE_LECTIN_1	MRC1 COLEC10 COLEC11 CLEC4C	1.37e-03	80	112	4	PS00615
Domain	MBT	SFMBT1 SFMBT2	1.55e-03	10	112	2	PF02820
Domain	Mbt	SFMBT1 SFMBT2	1.55e-03	10	112	2	IPR004092
Domain	Lectin_C	MRC1 COLEC10 COLEC11 CLEC4C	1.64e-03	84	112	4	PF00059
Domain	CLECT	MRC1 COLEC10 COLEC11 CLEC4C	1.64e-03	84	112	4	SM00034
Domain	C_TYPE_LECTIN_2	MRC1 COLEC10 COLEC11 CLEC4C	1.71e-03	85	112	4	PS50041
Domain	EGF_CA	VLDLR FBN1 NOTCH2 NOTCH3	1.78e-03	86	112	4	PF07645
Domain	C-type_lectin-like	MRC1 COLEC10 COLEC11 CLEC4C	1.78e-03	86	112	4	IPR001304
Domain	SAM_2	SFMBT1 DGKD SFMBT2	2.18e-03	43	112	3	PF07647
Domain	Growth_fac_rcpt_	VLDLR GPR179 FBN1 NOTCH2 NOTCH3	2.50e-03	156	112	5	IPR009030
Domain	-	MRC1 ELSPBP1	2.66e-03	13	112	2	2.10.10.10
Domain	EGF_Ca-bd_CS	VLDLR FBN1 NOTCH2 NOTCH3	2.77e-03	97	112	4	IPR018097
Domain	-	MRC1 COLEC10 COLEC11 CLEC4C	2.77e-03	97	112	4	3.10.100.10
Domain	ZINC_PROTEASE	ERAP1 ADAM30 ADAMTS12 PAPPA	2.87e-03	98	112	4	PS00142
Domain	EGF	VLDLR VWDE GPR179 FBN1 NOTCH2 NOTCH3	2.94e-03	235	112	6	SM00181
Domain	EGF_3	VLDLR ADAM30 VWDE FBN1 NOTCH2 NOTCH3	2.94e-03	235	112	6	PS50026
Domain	EGF_CA	VLDLR FBN1 NOTCH2 NOTCH3	2.98e-03	99	112	4	PS01187
Domain	C-type_lectin-like/link	MRC1 COLEC10 COLEC11 CLEC4C	2.98e-03	99	112	4	IPR016186
Domain	ASX_HYDROXYL	VLDLR FBN1 NOTCH2 NOTCH3	3.09e-03	100	112	4	PS00010
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH1	3.09e-03	14	112	2	IPR024317
Domain	FN_type2_col-bd	MRC1 ELSPBP1	3.09e-03	14	112	2	IPR000562
Domain	FN2_2	MRC1 ELSPBP1	3.09e-03	14	112	2	PS51092
Domain	Dynein_HC_stalk	DNAH2 DNAH1	3.09e-03	14	112	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH1	3.09e-03	14	112	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH1	3.09e-03	14	112	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH1	3.09e-03	14	112	2	IPR011704
Domain	FN2_1	MRC1 ELSPBP1	3.09e-03	14	112	2	PS00023
Domain	Calpain_cysteine_protease	CAPN6 CAPN15	3.09e-03	14	112	2	IPR022684
Domain	MT	DNAH2 DNAH1	3.09e-03	14	112	2	PF12777
Domain	AAA_8	DNAH2 DNAH1	3.09e-03	14	112	2	PF12780
Domain	fn2	MRC1 ELSPBP1	3.09e-03	14	112	2	PF00040
Domain	FN2	MRC1 ELSPBP1	3.09e-03	14	112	2	SM00059
Domain	AAA_5	DNAH2 DNAH1	3.09e-03	14	112	2	PF07728
Domain	DHC_fam	DNAH2 DNAH1	3.56e-03	15	112	2	IPR026983
Domain	Diacylglycerol_kinase_cat_dom	CERKL DGKD	3.56e-03	15	112	2	IPR001206
Domain	Peptidase_C2	CAPN6 CAPN15	3.56e-03	15	112	2	PF00648
Domain	DAGK	CERKL DGKD	3.56e-03	15	112	2	PS50146
Domain	Dynein_heavy	DNAH2 DNAH1	3.56e-03	15	112	2	PF03028
Domain	CysPc	CAPN6 CAPN15	3.56e-03	15	112	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN6 CAPN15	3.56e-03	15	112	2	IPR001300
Domain	DAGK_cat	CERKL DGKD	3.56e-03	15	112	2	PF00781
Domain	Dynein_heavy_dom	DNAH2 DNAH1	3.56e-03	15	112	2	IPR004273
Domain	CALPAIN_CAT	CAPN6 CAPN15	3.56e-03	15	112	2	PS50203
Domain	EGF-type_Asp/Asn_hydroxyl_site	VLDLR FBN1 NOTCH2 NOTCH3	3.81e-03	106	112	4	IPR000152
Domain	EGF-like_dom	VLDLR ADAM30 VWDE FBN1 NOTCH2 NOTCH3	3.90e-03	249	112	6	IPR000742
Domain	CTDL_fold	MRC1 COLEC10 COLEC11 CLEC4C	3.94e-03	107	112	4	IPR016187
Domain	EGF_1	VLDLR ADAM30 VWDE FBN1 NOTCH2 NOTCH3	4.38e-03	255	112	6	PS00022
Domain	NAD/diacylglycerol_kinase	CERKL DGKD	4.57e-03	17	112	2	IPR016064
Domain	WD40	DMXL2 WDR7 TBL1Y CORO1A DNAI2 WDR72	4.72e-03	259	112	6	PF00400
Domain	EGF-like_CS	VLDLR ADAM30 VWDE FBN1 NOTCH2 NOTCH3	4.90e-03	261	112	6	IPR013032
Domain	EGF_2	VLDLR ADAM30 VWDE FBN1 NOTCH2 NOTCH3	5.27e-03	265	112	6	PS01186
Domain	WD40	DMXL2 WDR7 TBL1Y CORO1A DNAI2 WDR72	5.56e-03	268	112	6	SM00320
Domain	WD40_repeat	DMXL2 WDR7 TBL1Y CORO1A DNAI2 WDR72	5.97e-03	272	112	6	IPR001680
Pathway	KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_N_TO_LECTIN_PATHWAY_OF_COAGULATION_CASCADE	COLEC10 COLEC11 FCN2	4.03e-06	6	84	3	M47785
Pathway	REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION	COLEC10 COLEC11 FCN2	7.02e-06	7	84	3	MM14654
Pathway	REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION	COLEC10 COLEC11 FCN2	1.12e-05	8	84	3	M27005
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN	COLEC10 COLEC11 FCN2	1.12e-05	8	84	3	M47784
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_FIBRINOGEN_TO_FIBRIN	COLEC10 COLEC11 FCN2	2.38e-05	10	84	3	M47879
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	COLEC10 COLEC11 FCN2	3.25e-05	11	84	3	M47874
Pathway	WP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS	LCK CD4 PPP3CB	2.16e-04	20	84	3	M48330
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH2 NOTCH3	3.47e-04	5	84	2	M27411
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH2 NOTCH3	5.18e-04	6	84	2	M27068
Pathway	REACTOME_INFECTION_WITH_MYCOBACTERIUM_TUBERCULOSIS	MRC1 RNF213 CORO1A	5.38e-04	27	84	3	M29816
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH2 DNAH1 DNAI2	5.38e-04	27	84	3	M47755
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	DMXL2 NMNAT2 GCNT3 CAPN6 DNAH2 ADAM30 LCK PPM1A ADAMTS12 PPP4C LATS2 KDM2A	6.87e-06	730	117	12	34857952
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DMXL2 SPTBN2 RNF213 DGKD MORC2 RALGAPA2 SCAF4 SPON1 KDM2A MED12	6.89e-06	493	117	10	15368895
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KIAA0408 FNDC3B DMXL2 DGKD IVNS1ABP RABGEF1 KDM2A MYOM2 NOTCH2 NOTCH3	7.40e-06	497	117	10	23414517
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	GFRAL HCN1 ITSN1 SPTBN2 INTS1 DNAH2 RNF213 PPM1A PRDM2 IVNS1ABP R3HCC1L ARHGAP20	7.46e-06	736	117	12	29676528
Pubmed	Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.	LCK CD4	1.12e-05	2	117	2	19439470
Pubmed	HIV-1 Nef disrupts maturation of CD4+ T cells through CD4/Lck modulation.	LCK CD4	1.12e-05	2	117	2	20826747
Pubmed	Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice.	SFMBT2 NFAT5	1.12e-05	2	117	2	24389345
Pubmed	Genetic variation of COLEC10 and COLEC11 and association with serum levels of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1).	COLEC10 COLEC11	1.12e-05	2	117	2	25710878
Pubmed	NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.	NOTCH2 NOTCH3	1.12e-05	2	117	2	34257585
Pubmed	Human immunodeficiency virus type 1 glycoprotein precursor retains a CD4-p56lck complex in the endoplasmic reticulum.	LCK CD4	1.12e-05	2	117	2	1548763
Pubmed	Effect of human immunodeficiency virus gp120 glycoprotein on the association of the protein tyrosine kinase p56lck with CD4 in human T lymphocytes.	LCK CD4	1.12e-05	2	117	2	2040625
Pubmed	Interaction of human immunodeficiency virus glycoprotein 160 with CD4 in Jurkat cells increases p56lck autophosphorylation and kinase activity.	LCK CD4	1.12e-05	2	117	2	1535787
Pubmed	β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1.	ERN1 ERAP1	1.12e-05	2	117	2	31896552
Pubmed	Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef.	LCK CD4	1.12e-05	2	117	2	8871625
Pubmed	Interaction of p56lck with CD4 in the yeast two-hybrid system.	LCK CD4	1.12e-05	2	117	2	7486703
Pubmed	Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation.	COLEC10 COLEC11	1.12e-05	2	117	2	27341702
Pubmed	Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.	NOTCH2 NOTCH3	1.12e-05	2	117	2	26640406
Pubmed	HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4.	LCK CD4	1.12e-05	2	117	2	7871751
Pubmed	Notch2 and Notch3 function together to regulate vascular smooth muscle development.	NOTCH2 NOTCH3	1.12e-05	2	117	2	22615991
Pubmed	Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.	COLEC10 COLEC11	1.12e-05	2	117	2	25912189
Pubmed	The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck.	LCK CD4	1.12e-05	2	117	2	25829544
Pubmed	Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloid-committed leukemic cell lines.	LCK CSF2RB	1.12e-05	2	117	2	1638019
Pubmed	Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail.	LCK CD4	1.12e-05	2	117	2	7831289
Pubmed	Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.	NOTCH2 NOTCH3	1.12e-05	2	117	2	24336671
Pubmed	HIV-1 gp160 decreases the K+ voltage-gated current from Jurkat E6.1 T cells by up-phosphorylation.	LCK CD4	1.12e-05	2	117	2	9989602
Pubmed	A membrane proximal domain of the human interleukin-3 receptor beta c subunit that signals DNA synthesis in NIH 3T3 cells specifically binds a complex of Src and Janus family tyrosine kinases and phosphatidylinositol 3-kinase.	LCK CSF2RB	1.12e-05	2	117	2	7896837
Pubmed	Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.	FBN1 NOTCH3	1.12e-05	2	117	2	32616814
Pubmed	Sequestration of p56(lck) by gp120, a model for TCR desensitization.	LCK CD4	1.12e-05	2	117	2	9036944
Pubmed	p56Lck anchors CD4 to distinct microdomains on microvilli.	LCK CD4	1.12e-05	2	117	2	11854499
Pubmed	The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck.	LCK CD4	1.12e-05	2	117	2	3262426
Pubmed	Expression of the signal transducing regions of CD4-like and lck genes in murine egg.	LCK CD4	1.12e-05	2	117	2	1370884
Pubmed	Internalization of HIV glycoprotein gp120 is associated with down-modulation of membrane CD4 and p56lck together with impairment of T cell activation.	LCK CD4	1.12e-05	2	117	2	1535086
Pubmed	The effect of p56lck, a lymphocyte specific protein tyrosine kinase, on the syncytium formation induced by human immunodeficiency virus envelope glycoprotein.	LCK CD4	1.12e-05	2	117	2	1622897
Pubmed	Repression of human immunodeficiency virus type 1 long terminal repeat-driven gene expression by binding of the virus to its primary cellular receptor, the CD4 molecule.	LCK CD4	1.12e-05	2	117	2	8648738
Pubmed	Molecular analysis of the interaction of p56lck with the CD4 and CD8 antigens.	LCK CD4	1.12e-05	2	117	2	1835265
Pubmed	CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa.	COLEC10 COLEC11	1.12e-05	2	117	2	30108587
Pubmed	Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.	NF1 CSF2RB	1.12e-05	2	117	2	17090653
Pubmed	Are sense-antisense peptide interactions between HIV-1 (gp120), CD4, and the proto oncogene product p56lck important?	LCK CD4	1.12e-05	2	117	2	1491632
Pubmed	Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs.	LCK CD4	1.12e-05	2	117	2	17005671
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E DMXL2 WDR7 TBL1Y ASIC1 HCN1 ITSN1 SPTBN2 TNRC6B NF1 PPP3CB RABGEF1 FRMPD3	2.26e-05	963	117	13	28671696
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DMXL2 DPY19L1 MORC2 IVNS1ABP NFAT5	2.31e-05	100	117	5	10048485
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SFMBT1 TRO CEP295NL ZER1 PRKN NOTCH3	2.33e-05	168	117	6	30631154
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	FNDC3B GFRAL DPY19L2 ERAP1 INTS1 ADAM30 COLEC10 ADAMTS12 COLEC11 SLITRK2 CD163L1 CLEC4C GSG1	2.85e-05	985	117	13	12975309
Pubmed	Complementary and combinatorial patterns of Notch gene family expression during early mouse development.	NOTCH2 NOTCH3	3.36e-05	3	117	2	8645602
Pubmed	HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck.	LCK CD4	3.36e-05	3	117	2	9043947
Pubmed	Binding of human immunodeficiency virus type 1 to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway.	LCK CD4	3.36e-05	3	117	2	8887682
Pubmed	Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.	NOTCH2 NOTCH3	3.36e-05	3	117	2	27697639
Pubmed	HIV envelope-directed signaling aberrancies and cell death of CD4+ T cells in the absence of TCR co-stimulation.	LCK CD4	3.36e-05	3	117	2	8671590
Pubmed	Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.	KDM2A KDM7A	3.36e-05	3	117	2	39273051
Pubmed	The oxygen-substituted palmitic acid analogue, 13-oxypalmitic acid, inhibits Lck localization to lipid rafts and T cell signaling.	LCK CD4	3.36e-05	3	117	2	12007789
Pubmed	HIV infection in vitro enhances the activity of src-family protein tyrosine kinases.	LCK CD4	3.36e-05	3	117	2	8883579
Pubmed	A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve.	NF1 CSF2RB	3.36e-05	3	117	2	12427839
Pubmed	gp120 ligation of CD4 induces p56lck activation and TCR desensitization independent of TCR tyrosine phosphorylation.	LCK CD4	3.36e-05	3	117	2	7522245
Pubmed	Enhanced IRE1α Phosphorylation/Oligomerization-Triggered XBP1 Splicing Contributes to Parkin-Mediated Prevention of SH-SY5Y Cell Death under Nitrosative Stress.	ERN1 PRKN	3.36e-05	3	117	2	36768338
Pubmed	Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome.	COLEC10 COLEC11	3.36e-05	3	117	2	32751929
Pubmed	Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.	NOTCH2 NOTCH3	3.36e-05	3	117	2	7615640
Pubmed	The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.	NOTCH2 NOTCH3	3.36e-05	3	117	2	7918097
Pubmed	Interactions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeast.	LCK CD4	3.36e-05	3	117	2	7664803
Pubmed	Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.	NOTCH2 NOTCH3	3.36e-05	3	117	2	21471519
Pubmed	CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage.	LCK CD4	3.36e-05	3	117	2	12055221
Pubmed	A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.	LCK CD4	3.36e-05	3	117	2	14500983
Pubmed	Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.	NOTCH2 NOTCH3	3.36e-05	3	117	2	29767458
Pubmed	The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.	NOTCH2 NOTCH3	3.36e-05	3	117	2	7698746
Pubmed	Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney.	SLC22A9 SLC22A8	3.36e-05	3	117	2	18414781
Pubmed	T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.	NOTCH2 NOTCH3	3.36e-05	3	117	2	27717083
Pubmed	Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.	NOTCH2 NOTCH3	3.36e-05	3	117	2	25957400
Pubmed	Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef.	LCK CD4	3.36e-05	3	117	2	24706755
Pubmed	A role for CD4+ T cells in the pathogenesis of skin fibrosis in tight skin mice.	CD4 FBN1	3.36e-05	3	117	2	7911425
Pubmed	The protein tyrosine kinase p56lck is required for triggering NF-kappaB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4.	LCK CD4	3.36e-05	3	117	2	9621091
Pubmed	FE65 as a link between VLDLR and APP to regulate their trafficking and processing.	VLDLR APBB1	3.36e-05	3	117	2	22429478
Pubmed	A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter.	DMXL2 WDR7	3.36e-05	3	117	2	12786944
Pubmed	CXCR4 Tropic HIV-1 gp120 Inhibition of SDF-1α-Induced Chemotaxis Requires Lck and is Associated with Cofilin Phosphorylation.	LCK CD4	3.36e-05	3	117	2	20835359
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CACNA1E DMXL2 WDR7 SPTBN2 NF1 PPP3CB PKP1	4.85e-05	281	117	7	28706196
Pubmed	Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.	SLC22A9 SLC22A8	6.70e-05	4	117	2	15037815
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH2 NOTCH3	6.70e-05	4	117	2	24145721
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH2 NOTCH3	6.70e-05	4	117	2	20069356
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH2 NOTCH3	6.70e-05	4	117	2	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH2 NOTCH3	6.70e-05	4	117	2	28669409
Pubmed	The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol-anchored proteins Thy-1 and CD48 in rat thymocytes is dependent on the state of cellular activation.	LCK CD4	6.70e-05	4	117	2	8104794
Pubmed	Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.	NOTCH2 NOTCH3	6.70e-05	4	117	2	10551863
Pubmed	A deficiency of lunatic fringe is associated with cystic dilation of the rete testis.	NOTCH2 NOTCH3	6.70e-05	4	117	2	18801836
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH2 NOTCH3	6.70e-05	4	117	2	11401408
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH2 NOTCH3	6.70e-05	4	117	2	8898100
Pubmed	Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.	NOTCH2 NOTCH3	6.70e-05	4	117	2	11978185
Pubmed	Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.	COLEC11 FCN2	6.70e-05	4	117	2	28739878
Pubmed	Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.	SLC22A9 SLC22A8	6.70e-05	4	117	2	19417012
Pubmed	Notch Signaling Participates in TGF-β-Induced SOST Expression Under Intermittent Compressive Stress.	NOTCH2 NOTCH3	6.70e-05	4	117	2	27966788
Pubmed	Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system.	COLEC10 COLEC11	6.70e-05	4	117	2	24174618
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH2 NOTCH3	6.70e-05	4	117	2	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH2 NOTCH3	6.70e-05	4	117	2	17920003
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH2 NOTCH3	6.70e-05	4	117	2	28061457
Pubmed	Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis.	EPHX2 NOTCH3	6.70e-05	4	117	2	27266621
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH2 NOTCH3	6.70e-05	4	117	2	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH2 NOTCH3	6.70e-05	4	117	2	24151014
Pubmed	Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium.	NOTCH2 NOTCH3	6.70e-05	4	117	2	18155189
Pubmed	Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.	NOTCH2 NOTCH3	6.70e-05	4	117	2	23999936
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH2 NOTCH3	6.70e-05	4	117	2	10194420
Pubmed	Tyrosine phosphorylation induced by C4 peptide constructs from HIV Gp120.	LCK CD4	6.70e-05	4	117	2	10422873
Pubmed	NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.	NOTCH2 NOTCH3	6.70e-05	4	117	2	18156632
Pubmed	Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro.	UBE2G2 PRKN	6.70e-05	4	117	2	16339143
Interaction	PLOD3 interactions	COLEC10 PPM1A COLEC11 PPP4C PTPRN ANLN PRKN GEN1	8.44e-06	183	112	8	int:PLOD3
Interaction	NTN5 interactions	VWDE FBN1 NOTCH2 NOTCH3	8.82e-06	24	112	4	int:NTN5
Interaction	RBPJ interactions	SFMBT1 SFMBT2 MTA3 ZBTB10 PRKN KDM2A TDP1 NOTCH2 NOTCH3	1.24e-05	254	112	9	int:RBPJ
Interaction	ST14 interactions	VLDLR ADAM30 BCHE ELSPBP1 FBN1 SPON1 NOTCH2 NOTCH3	2.06e-05	207	112	8	int:ST14
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPEF2 PPP4C PPP3CB	2.31e-05	13	80	3	693
GeneFamily	Dyneins, axonemal	DNAH2 DNAH1 DNAI2	5.42e-05	17	80	3	536
GeneFamily	Sterile alpha motif domain containing\|MBT domain containing	SFMBT1 SFMBT2	6.82e-04	9	80	2	1263
GeneFamily	Collectins	COLEC10 COLEC11	8.50e-04	10	80	2	491
GeneFamily	WD repeat domain containing	DMXL2 WDR7 TBL1Y CORO1A DNAI2 WDR72	1.07e-03	262	80	6	362
GeneFamily	C2 domain containing\|Calpains	CAPN6 CAPN15	1.96e-03	15	80	2	975
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	NMNAT2 DPY19L1 RNF213 ADAMTS12 FBN1 ARHGAP20 NOTCH2	4.29e-07	176	117	7	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GCNT3 LCK IZUMO1R VWDE CORO1A CD4	5.50e-06	168	117	6	2d2eab3190374f79f373e31c8b062ff4e1766396
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GCNT3 LCK IZUMO1R VWDE CORO1A CD4	5.50e-06	168	117	6	df58156721457b34af1e81c0eb8a7243cbbfb303
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LCK IZUMO1R ZP2 CORO1A CD4 SLC17A9	5.50e-06	168	117	6	68ee3b3b012b56584e313813feb16e632e3f72d2
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LCK IZUMO1R SFMBT2 CORO1A CD4 SLC17A9	6.30e-06	172	117	6	1aecc98a3eadabae0f1f328091a9733d916017ec
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	DPY19L2 WDR7 RNF213 CD4 ANLN NFAT5	7.18e-06	176	117	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LCORL ASIC1 BCHE GPR179 NF1 PRKN	7.42e-06	177	117	6	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	MRC1 DMXL2 ITSN1 ANLN CD163L1 NOTCH3	8.17e-06	180	117	6	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VLDLR CAPN6 FBN1 SPON1 PAPPA ARHGAP20	9.26e-06	184	117	6	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E SPTBN2 LCK CORO1A OTOF PTPRN	9.84e-06	186	117	6	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MRC1 ITSN1 TNRC6B SCAF4 CD163L1 KDM2A	1.01e-05	187	117	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0408 ADAMTS12 SLITRK2 FBN1 DNAI2 ARHGAP20	1.14e-05	191	117	6	d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KIAA0408 CAPN6 BCHE TACC2 FBN1 PKP1	1.18e-05	192	117	6	4ed5040594ba2d0639f0990697504ecef872ca70
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	MRC1 DMXL2 RNF213 CD4 ANLN CD163L1	1.18e-05	192	117	6	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KIAA0408 CAPN6 BCHE TACC2 FBN1 PKP1	1.18e-05	192	117	6	d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHX2 CERKL ABCA3 CAPN6 CSF2RB PAPPA	1.25e-05	194	117	6	f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GCNT3 SPTBN2 TACC2 HS6ST1 PAPPA KDM7A	1.25e-05	194	117	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GCNT3 SPTBN2 TACC2 HS6ST1 PAPPA KDM7A	1.25e-05	194	117	6	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 LCK SFMBT2 CORO1A CD4 CD163L1	1.29e-05	195	117	6	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 DMXL2 RNF213 SFMBT2 CD4 CD163L1	1.36e-05	197	117	6	10190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MRC1 DMXL2 ITSN1 SFMBT2 CD4 CD163L1	1.36e-05	197	117	6	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MRC1 DMXL2 ITSN1 SFMBT2 CD4 CD163L1	1.36e-05	197	117	6	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 BCHE ADAMTS12 FBN1 SPON1 ARHGAP20	1.44e-05	199	117	6	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 DMXL2 RNF213 SFMBT2 CD4 CD163L1	1.44e-05	199	117	6	5ceeed92f831d068ff4bb3994f420002338330e7
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIAA0408 BCHE ADAMTS12 FBN1 SPON1 ARHGAP20	1.44e-05	199	117	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIAA0408 VLDLR CAPN6 BCHE SPON1 PAPPA	1.44e-05	199	117	6	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIAA0408 NMNAT2 ITSN1 ADAMTS12 FBN1 GSPT2	1.44e-05	199	117	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 BCHE ADAMTS12 FBN1 SPON1 ARHGAP20	1.49e-05	200	117	6	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 BCHE ADAMTS12 FBN1 SPON1 ARHGAP20	1.49e-05	200	117	6	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	KIAA0408 BCHE ADAMTS12 FBN1 SPON1 ARHGAP20	1.49e-05	200	117	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCN1 LINC00528 IVNS1ABP CSF2RB FRMPD3	1.92e-05	124	117	5	80526f503e1477b9455d10f27f7e6b56caea3a66
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA0408 CERKL COLEC10 ANLN TDP1	2.59e-05	132	117	5	46c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCell	LPS-IL1RA+antiTNF-Unknown\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA0408 CERKL COLEC10 ANLN TDP1	2.59e-05	132	117	5	a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR179 ADAMTS12 ZER1 GEN1 WDR72	3.21e-05	138	117	5	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR179 ADAMTS12 ZER1 GEN1 WDR72	3.68e-05	142	117	5	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAGE1 C9orf43 CD4 WDR72	4.12e-05	73	117	4	582faedb369a099d0acf1565413e6b3ca2cfc564
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	SFMBT1 TBL1Y BCHE ADAMTS12 SLITRK2	4.48e-05	148	117	5	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LCK DENND11 IZUMO1R CORO1A CD4	4.93e-05	151	117	5	75c068b3e3aae5f9ba64d5fa5d1e2105a60e4293
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LCK IVNS1ABP HS6ST1 PAPPA WDR72	4.93e-05	151	117	5	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CD4 CD163L1 WDR72	5.76e-05	156	117	5	0bd32876413f3308f838f266e8c39ea0937ce5b9
ToppCell	COVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	DPY19L2 TRO SPTBN2 FBN1 CSF2RB	6.12e-05	158	117	5	0d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	KIAA0408 DMGDH PRKN MYOM2 ARHGAP20	6.49e-05	160	117	5	8a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCell	TCGA-Bladder-Solid_Tissue_Normal\|TCGA-Bladder / Sample_Type by Project: Shred V9	KIAA0408 DMGDH PRKN MYOM2 ARHGAP20	6.49e-05	160	117	5	d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	KIAA0408 DMGDH PRKN MYOM2 ARHGAP20	6.49e-05	160	117	5	c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 CACNA1E TRO ADAM30 R3HCC1L	6.89e-05	162	117	5	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	facs-Thymus-Thymus_Flowthrough-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A PPP4C NOTCH2	6.89e-05	162	117	5	7e6d20704d77b28512690f882f9ddbbd9c5c3228
ToppCell	facs-Thymus-Thymus_Flowthrough\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A PPP4C NOTCH2	6.89e-05	162	117	5	2c193f766f2cefe67682f34325d1de6aed778f49
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MRC1 VLDLR NMNAT2 BCHE ADAMTS12	7.09e-05	163	117	5	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EID3 DPY19L1 NAP1L5 APBB1 NOTCH3	7.09e-05	163	117	5	1c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMGDH LCK IZUMO1R CORO1A CD4	7.73e-05	166	117	5	d22a08b415ef9e48398d69f3e45b04c33a085411
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E NAP1L5 CD163L1 SPON1 NOTCH3	7.95e-05	167	117	5	e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell	Healthy_donor-HSPC\|World / disease group, cell group and cell class (v2)	DPY19L2 TRO VWDE C9orf43 NOTCH3	7.95e-05	167	117	5	70630ebdfee8171d625811844f8a7c94736d101e
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 COLEC11 SPON1 PAPPA NOTCH3	8.18e-05	168	117	5	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 COLEC11 SPON1 PAPPA NOTCH3	8.18e-05	168	117	5	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LCK DENND11 ALKBH1 PRKN GEN1	8.18e-05	168	117	5	235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LCK IZUMO1R ZP2 CORO1A CD4	8.65e-05	170	117	5	67e78e3c1d4cd3c6eaa5d0a9785b6cd8a3b08039
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	8.65e-05	170	117	5	7040f7b1e4d8d26db787449e557371c5d872c95a
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LCK IZUMO1R CD4 PPP3CB SLC17A9	8.65e-05	170	117	5	bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SFMBT1 DMGDH MRC1 LINC00528 ARHGAP20	8.89e-05	171	117	5	7c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERN1 SFMBT2 CD4 CSF2RB CLEC4C	8.89e-05	171	117	5	39c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK PPEF2 IZUMO1R CORO1A CD4	9.13e-05	172	117	5	b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCell	Healthy_donor-HSPC\|Healthy_donor / disease group, cell group and cell class (v2)	DPY19L2 TRO VWDE C9orf43 NOTCH3	9.13e-05	172	117	5	bc7549faadfc92c683c0e26bea380458706774b5
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	5b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	a6e73a40b0d5356564a594053e772f9d061a5919
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R SFMBT2 CORO1A CD4	9.39e-05	173	117	5	82fa5ff6a00216a21a37fafeaf3e21e964c61d47
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R SFMBT2 CORO1A CD4	9.39e-05	173	117	5	13f67f61edb734ff846da92d41e81ec4670a2b66
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	1edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E RNF213 RALGAPA2 LINC00528 IVNS1ABP	9.39e-05	173	117	5	c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 SLC17A9	9.64e-05	174	117	5	fedadde222df1952d6456f4f3413c01579146e1f
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS12 COLEC11 FBN1 SPON1 NOTCH3	9.64e-05	174	117	5	778e0317c0c63fa4efd74114feb760975b819d92
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 SLC17A9	9.64e-05	174	117	5	e69a011ae9698368923223d3af3243e609c08c83
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSPT2 MTA3 CD163L1 GSG1 NOTCH3	9.64e-05	174	117	5	0fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSPT2 MTA3 CD163L1 GSG1 NOTCH3	9.64e-05	174	117	5	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	9.91e-05	175	117	5	d82153bdb0c5cca96485d6b0579440f9c9e3abe2
ToppCell	facs-Trachea-nan-18m-Lymphocytic-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAGE1 LCK IZUMO1R CORO1A CD163L1	1.02e-04	176	117	5	14c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	1.02e-04	176	117	5	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFMBT1 IZUMO1R CD4 HS6ST1 DDX20	1.02e-04	176	117	5	91ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCell	facs-Trachea-nan-18m-Lymphocytic\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAGE1 LCK IZUMO1R CORO1A CD163L1	1.02e-04	176	117	5	9dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCell	facs-MAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R VWDE CORO1A CD4	1.02e-04	176	117	5	359a57aea89d8e6776eaefb0c3553a0dbcad5e58
ToppCell	droplet-Bladder-nan-24m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	1.02e-04	176	117	5	0089b50d607f4d2f18639fab0f3fc779227baa7a
ToppCell	facs-Trachea-nan-18m-Lymphocytic-T_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAGE1 LCK IZUMO1R CORO1A CD163L1	1.02e-04	176	117	5	d990e7af8120210100d13caa0465b27cf77a451a
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L5 LCK COLEC11 CORO1A CD163L1	1.05e-04	177	117	5	7853430fb0d1a18d835e8956777e0616c5d7d412
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	WDR7 RNF213 CD4 ANLN NFAT5	1.05e-04	177	117	5	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 SLC17A9	1.05e-04	177	117	5	9d2d70d53b919fed3328812889a55e5e1a0759de
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VLDLR CAPN6 BCHE PAPPA NOTCH2	1.05e-04	177	117	5	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	1.05e-04	177	117	5	be35bb178fbc149f8a12984c012d98b486325ba9
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT3 NAP1L5 VWDE SFMBT2 OTOF	1.05e-04	177	117	5	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	1.05e-04	177	117	5	31201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCK IZUMO1R CORO1A CD4 CD163L1	1.05e-04	177	117	5	89d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCell	severe_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	DPY19L2 TRO VWDE C9orf43 FBN1	1.05e-04	177	117	5	289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCell	facs-Skin-Anagen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L5 LCK COLEC11 CORO1A CD163L1	1.05e-04	177	117	5	395f005f019aabb18738d3a10a04c37f216deda3
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L5 LCK COLEC11 CORO1A CD163L1	1.05e-04	177	117	5	9a5bf67a801826d094f679dd2189b62296c9694f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT3 NAP1L5 VWDE SFMBT2 OTOF	1.05e-04	177	117	5	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS12 COLEC11 FBN1 SPON1 NOTCH3	1.07e-04	178	117	5	9fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERN1 LCK CORO1A OTOF CLEC4C	1.07e-04	178	117	5	f52f837e948deb6a2d031325f49891bca8d375da
ToppCell	COVID-19_Mild-Hematopoietic_SC-HSPC\|COVID-19_Mild / Disease group, lineage and cell class	DPY19L2 TRO SPTBN2 VWDE FBN1	1.10e-04	179	117	5	19fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPY19L2 TRO SPTBN2 VWDE FBN1	1.10e-04	179	117	5	4bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPY19L2 TRO SPTBN2 VWDE FBN1	1.10e-04	179	117	5	2f690f933bf6b99abeb31766e0b22bdbe36c1ba0
Drug	rhamnose	MRC1 GCNT3 BCHE COLEC10 ZP2 CD4 CSF2RB FCN2 SPON1 NOTCH2 NOTCH3	1.79e-06	356	114	11	CID000000840
Disease	metabolite measurement, body weight gain	TACC2 DNAI2 PRKN ZCCHC7	9.86e-08	12	113	4	EFO_0004566, EFO_0004725
Disease	Glioblastoma Multiforme	ERN1 BCHE NF1 PRKN NOTCH2 NOTCH3	4.51e-06	111	113	6	C1621958
Disease	Glioblastoma	BCHE NF1 PRKN NOTCH2 NOTCH3	1.35e-05	79	113	5	C0017636
Disease	Giant Cell Glioblastoma	BCHE NF1 PRKN NOTCH2 NOTCH3	1.83e-05	84	113	5	C0334588
Disease	Malpuech facial clefting syndrome	COLEC10 COLEC11	4.35e-05	3	113	2	C0796032
Disease	Craniofacial ulnar renal syndrome	COLEC10 COLEC11	4.35e-05	3	113	2	C4303860
Disease	Cerebral Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0750935
Disease	Intracranial Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0750936
Disease	Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0004114
Disease	Grade I Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0205768
Disease	Mixed oligoastrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0547065
Disease	Pilocytic Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0334583
Disease	Juvenile Pilocytic Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0280783
Disease	Diffuse Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0280785
Disease	Childhood Cerebral Astrocytoma	NF1 LATS2 NOTCH2	1.18e-04	25	113	3	C0338070
Disease	Gemistocytic astrocytoma	NF1 LATS2 NOTCH2	1.33e-04	26	113	3	C0334581
Disease	Protoplasmic astrocytoma	NF1 LATS2 NOTCH2	1.33e-04	26	113	3	C0334580
Disease	Fibrillary Astrocytoma	NF1 LATS2 NOTCH2	1.33e-04	26	113	3	C0334582
Disease	collectin-11 measurement	COLEC10 COLEC11	1.44e-04	5	113	2	EFO_0008088
Disease	e3 ubiquitin-protein ligase RNF43 measurement	APBB1 BCHE	1.44e-04	5	113	2	EFO_0021886
Disease	pulmonary alveolar proteinosis (implicated_via_orthology)	ABCA3 CSF2RB	1.44e-04	5	113	2	DOID:12120 (implicated_via_orthology)
Disease	Cerebellar Hypoplasia	VLDLR NMNAT2	1.44e-04	5	113	2	C0266470
Disease	Anaplastic astrocytoma	NF1 LATS2 NOTCH2	1.50e-04	27	113	3	C0334579
Disease	colorectal cancer (implicated_via_orthology)	LCK NOTCH2 NOTCH3	2.06e-04	30	113	3	DOID:9256 (implicated_via_orthology)
Disease	ficolin-1 measurement	APBB1 FCN2	2.16e-04	6	113	2	EFO_0008134
Disease	pulmonary alveolar proteinosis (is_implicated_in)	ABCA3 CSF2RB	2.16e-04	6	113	2	DOID:12120 (is_implicated_in)
Disease	intestinal cancer (implicated_via_orthology)	LCK NOTCH2 NOTCH3	2.50e-04	32	113	3	DOID:10155 (implicated_via_orthology)
Disease	hyperuricemia	SFMBT1 NFAT5 WDR72	2.74e-04	33	113	3	EFO_0009104
Disease	angiopoietin-related protein 4 measurement	BCHE COLEC11	3.01e-04	7	113	2	EFO_0020149
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH2 NOTCH3	3.01e-04	7	113	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH2 NOTCH3	3.01e-04	7	113	2	DOID:3620 (implicated_via_orthology)
Disease	collectin-10 measurement	COLEC10 COLEC11	5.14e-04	9	113	2	EFO_0801491
Disease	Malignant neoplasm of breast	FNDC3B ABCA3 GFRAL BCHE TACC2 SLC22A9 NF1 OTOF GEN1 MED12 NOTCH2 NOTCH3	8.59e-04	1074	113	12	C0006142
Disease	Parkinson Disease, Secondary Vascular	BCHE PRKN	9.36e-04	12	113	2	C0751414
Disease	Atherosclerotic Parkinsonism	BCHE PRKN	9.36e-04	12	113	2	C0751415
Disease	Secondary Parkinson Disease	BCHE PRKN	9.36e-04	12	113	2	C0030569
Disease	susceptibility to bacterial meningitis measurement	CERKL DPY19L2 NFAT5	1.05e-03	52	113	3	EFO_0008411
Disease	diastolic blood pressure, systolic blood pressure	MRC1 FNDC3B HCN1 DNAH2 TNRC6B CAGE1 FBN1 SPON1 NFAT5	1.12e-03	670	113	9	EFO_0006335, EFO_0006336
Disease	mannan-binding lectin serine protease 1 measurement	COLEC11 FCN2	1.48e-03	15	113	2	EFO_0008223
Disease	posterior thigh muscle volume	LCORL KDM2A	1.48e-03	15	113	2	EFO_0020931
Disease	verbal-numerical reasoning measurement	CACNA1E DMXL2 NMNAT2 LCORL	1.64e-03	131	113	4	EFO_0008394
Disease	Moyamoya Disease	RNF213 NF1	1.90e-03	17	113	2	C0026654
Disease	glucuronate measurement	FNDC3B WDR72	2.14e-03	18	113	2	EFO_0010486
Disease	opioid dependence	SPTBN2 TACC2 SFMBT2 PAPPA WDR72	2.23e-03	237	113	5	EFO_0005611
Disease	type 1 diabetes mellitus	DNAH2 ADAM30 COLEC10 BTN2A3P NOTCH2	2.44e-03	242	113	5	MONDO_0005147

Protein segments in the cluster

Peptide	Gene	Start	Entry
CLSPEENAEDMEVRW	BTN2A3P	51	Q96KV6
GAMWLSLCPDNEDLL	CEP295NL	61	Q96MC4
GSEMWNPNTDLSEDC	BCHE	106	P06276
RENCEMPDWEQSAES	CAGE1	281	Q8TC20
TGEAWQEIMLSCLGE	CACNA1E	1661	Q15878
DSMVEPCSMEDWQVC	ALKBH1	316	Q13686
GMWLSCEETVEEPAL	GSG1	96	Q2KHT4
MALLLSDWCPDGDAD	LINC00528	1	Q8N1L1
SDWAVDSNLCGAMDP	ABCA3	866	Q99758
EDCVEMLSSGRWNDT	COLEC10	246	Q9Y6Z7
MFWCEPNAASLSEAV	APBB1	636	O00213
SEDCTVMVWEIPDGG	CORO1A	101	P31146
WPLMNDEGEDNSSTV	DMXL2	1051	Q8TDJ6
PSGLMEECVDWDVEV	DDX20	441	Q9UHI6
GPIWLDDLNCTGMES	CD163L1	1096	Q9NR16
TLDIWDFMFEQCDPT	DNAI2	431	Q9GZS0
SMSCNPEPCEAWQVE	ADAMTS12	1416	P58397
SWESMFNDDGDCLDP	R3HCC1L	576	Q7Z5L2
AESWSPDACLGVKQM	RABGEF1	396	Q9UJ41
GTWTTVLVDDMLPCD	CAPN15	591	O75808
DGGDCSLTMENPWAN	NOTCH2	1451	Q04721
PSWCEEPAQANMDIS	PTPRN	676	Q16849
MCPWEEDILSSKLNG	KDM7A	541	Q6ZMT4
WLEMLDPEVVSSCPD	INTS1	1621	Q8N201
SCGEMYDSNIDDWIP	IVNS1ABP	431	Q9Y6Y0
AEICPWELDDNVMGQ	GPR179	1476	Q6PRD1
SRMAELCQWEITDPE	GPR179	2216	Q6PRD1
PTWAGDELLNICMNA	IZUMO1R	16	A6ND01
MEPSDLWDDVSNCRC	LATS2	836	Q9NRM7
PLFDSSDMTIAEWVC	ASPG	81	Q86U10
WDNDDMTDDIPESSL	ANLN	156	Q9NQW6
EPEELTDWSMDEKCS	LCORL	76	Q8N3X6
WMEGDPDKLSDCDDS	EID3	131	Q8N140
EDLWDSMASICPTDG	ERAP1	476	Q9NZ08
APDCWDQVDMESPGS	GSPT2	11	Q8IYD1
EVATDWMDTECPEAK	NOTCH3	1716	Q9UM47
GCSMPEIWDVEDPAN	DPY19L1	626	Q2PZI1
PSNEDVGLSMWSCDI	KIAA0408	351	Q6ZU52
SSHPEDDWMENIDVC	LCK	6	P06239
CNVEPSESNMRWAPE	MED12	1006	Q93074
LLTCMEDGLWSFPEA	PAPPA	1326	Q13219
EDGLWSFPEALCELM	PAPPA	1331	Q13219
GCSMLEIWDVEDPSN	DPY19L2	711	Q6NUT2
TNEAELSMGPWQTCE	RALGAPA2	856	Q2PPJ7
LSMGPWQTCEEDPEL	RALGAPA2	861	Q2PPJ7
LESEQSCSMWMEDSP	NFAT5	166	O94916
EGTDWSGCTLQEFMD	HS6ST1	226	O60243
DTWVCSMNPDPEQDR	MORC2	521	Q9Y6X9
CTDDMVWGDDLINSP	DNAH1	636	Q9P2D7
VCGLSDDEIEWQMAP	ADAM30	171	Q9UKF2
PPDCWVSLNEMVNDS	HCN1	326	O60741
EPVSCDLSDDMPWSA	CSF2RB	71	P32927
DCGHWTQMDKPTEVN	EPHX2	521	P34913
MDGEGLLNEELPNCW	KDM2A	656	Q9Y2K7
AWRVMEDACNDSDPG	GFRAL	41	Q6UXV0
GWIAPEMLSEDCKEN	ERN1	736	O75460
GMAWALQAADTCPEV	FCN2	21	Q15485
AAWGTEECEECPMRN	FBN1	986	P35555
MEWPEATNFACLIAG	FRMPD3	471	Q5JV73
EGNSCEILWETVPSM	FNDC3B	1066	Q53EP0
NMVEWCLPQDIDLEG	DENND11	91	A4D1U4
MDLPDESQWDETTCG	C9orf43	1	Q8TAL5
LTTDMDPSQQWCSDL	ITSN1	1211	Q15811
ESLLKSMPEESEDCW	CCDC102A	201	Q96A19
SMPEESEDCWEARSL	CCDC102A	206	Q96A19
DLNCMEDLLQSSVPW	GCNT3	206	O95395
LNPEAGMWQCLLSDS	CD4	361	P01730
ASENCFPWNVDGDLM	CERKL	516	Q49MI3
DCVEMVASGGWNDVA	COLEC11	241	Q9BWP8
AWGLEMNCDTNPLEA	DMGDH	726	Q9UI17
WLCQSAEPGDEESVM	DGKD	1091	Q16760
DESNKLWCPTTENMD	ELSPBP1	146	Q96BH3
IPWVQAAGEAEAMCA	GEN1	126	Q17RS7
NLDWEDSMALGCTTV	LINC01545	21	Q5VT33
DPQCWESSSVLLLEM	FAM237A	46	A0A1B0GTK4
VLGCWTVDDDPLMNR	CAPN6	356	Q9Y6Q1
LDREGQMDNPCSSWL	DNAH2	3716	Q9P225
MCDLLWSDPSEDFGN	PPP3CB	236	P16298
NDTQRAMEPCLDGWV	SLC22A8	86	Q8TCC7
CEGGMLDSDTLNPDW	SCAF4	616	O95104
LWVQDGECSEIMTGA	HEXA-AS1	61	Q9H8Q6
MCIDATDPEKGNWLR	PRDM2	86	Q13029
ETLCPTWDQMLVFDN	OTOF	1001	Q9HC10
VVDILWSDPMAQEGC	PPEF2	441	O14830
LKGDPTMSWNDINCE	MRC1	756	P22897
PVLCRDEMEEWSASE	MTA3	261	Q9BTC8
WCDGNSNMSREVVDP	PKP1	386	Q13835
LTDMWTASCVDEVGE	ARHGAP20	131	Q9P2F6
ETRLSQWLEEMPCVG	TAAR5	176	O14804
MLPECPIDCELTEWS	SPON1	661	Q9HCB6
SCWDDVLIPNRMSGE	PRKN	181	O60260
PNTSDADMEPCVDGW	SLC22A9	106	Q8IVM8
QELTGEMEGCAWTLE	NAP1L5	121	Q96NT1
LQENPWDCTCDIMGL	SLITRK2	526	Q9H156
DMAGDTQWSRPECQA	SLC17A9	11	Q9BYT1
PWGTCKAVTMDSDLD	ASIC1	286	P78348
VMEGKDIEDWSCCPT	CLEC4C	71	Q8WTT0
EPGMDLWEFCSETFQ	RNF213	2151	Q63HN8
ALMFLAWGEAQECSP	VWDE	11	Q8N2E2
GWCLSSSDDELQPEM	TDP1	86	Q9NUW8
DPWESSECTDVLMGR	ZNF441	101	Q8N8Z8
LWNITDETPDNCEMF	ZER1	551	Q7Z7L7
DAGMAEAWLCSQEPL	SPTBN2	2021	O15020
GPWNWDDMDIDCLTR	TRO	676	Q12816
LACDGIWDVMGNEEL	PPM1A	236	P35813
VESMDIFPVGWCEAN	SFMBT2	456	Q5VUG0
EDNFSLMLPGWDLCN	WDR72	836	Q3MJ13
WNPDTEAVLVAMSCF	NF1	696	P21359
PQQKMECWATSDAES	TACC2	1096	O95359
KWDPSGMLLASCSDD	TBL1Y	366	Q9BQ87
DNVESWMLLGCEVDD	ZCCHC7	171	Q8N3Z6
SVESMDIFPLGWCET	SFMBT1	431	Q9UHJ3
PSRWDESGEVCMSLD	ZBTB10	856	Q96DT7
PMCDLLWSDPEDTTG	PPP4C	191	P60510
SESGEMCLWDVSDGR	WDR7	86	Q9Y4E6
VLDDCWATSTMDPDS	ZP2	541	Q05996
IVDGSDMEEWPCIAS	TNRC6B	191	Q9UPQ9
DMEEWPCIASKDTES	TNRC6B	196	Q9UPQ9
EWEALIMGPEDTCFE	UBE2G2	36	P60604
ELVQPSGKNWCEEDM	VLDLR	696	P98155
GSEEMAWLQICEPTE	MYOM2	1281	P54296
SFCIPGLWNEADMEV	NMNAT2	206	Q9BZQ4