Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA2 ABCA4 XKR4 ABCA7 ATP8B2	1.97e-06	51	81	5	GO:0140303
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA2 ABCA4 ABCA7 ATP8B2	4.78e-06	28	81	4	GO:0140326
GeneOntologyMolecularFunction	medium-chain fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	1.63e-05	2	81	2	GO:0140981
GeneOntologyMolecularFunction	16-hydroxypalmitate dehydrogenase activity	CYP4A11 CYP4A22	1.63e-05	2	81	2	GO:0103002
GeneOntologyMolecularFunction	floppase activity	ABCA2 ABCA7 ATP8B2	3.47e-05	16	81	3	GO:0140328
GeneOntologyMolecularFunction	NACHT domain binding	TRIM16 TRIM16L	4.86e-05	3	81	2	GO:0032089
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH8 DYNC1H1	5.02e-05	18	81	3	GO:0008569
GeneOntologyMolecularFunction	retinol transmembrane transporter activity	ABCA4 STRA6	9.70e-05	4	81	2	GO:0034632
GeneOntologyMolecularFunction	lipid transporter activity	ABCA2 ABCA4 STRA6 XKR4 ABCA7 ATP8B2	1.46e-04	196	81	6	GO:0005319
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH8 DYNC1H1	1.96e-04	28	81	3	GO:0051959
GeneOntologyMolecularFunction	phospholipid transporter activity	ABCA4 XKR4 ABCA7 ATP8B2	2.33e-04	74	81	4	GO:0005548
GeneOntologyMolecularFunction	sphingosine N-acyltransferase activity	CERS2 CERS5	3.37e-04	7	81	2	GO:0050291
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4A11 CYP4A22	3.37e-04	7	81	2	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4A11 CYP4A22	3.37e-04	7	81	2	GO:0018685
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	ABCA4 SLC47A1 STRA6	4.17e-04	36	81	3	GO:0090482
GeneOntologyMolecularFunction	alcohol transmembrane transporter activity	ABCA4 STRA6	4.48e-04	8	81	2	GO:0015665
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA7 ATP8B2	4.48e-04	8	81	2	GO:0090554
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH8 DYNC1H1	4.52e-04	37	81	3	GO:0045505
GeneOntologyMolecularFunction	transporter activity	ABCA2 ABCA4 NALCN ATP6V0A4 HCN3 ORAI3 PKD2L1 SLC47A1 STRA6 XKR4 ABCA7 ATP8B2 SLC22A17 SLC29A4	6.30e-04	1289	81	14	GO:0005215
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4A11 CYP4A22	7.16e-04	10	81	2	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	7.16e-04	10	81	2	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	7.16e-04	10	81	2	GO:0102033
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 ABCA2 ABCA4 MYO9A ATP6V0A4 DNAH8 ABCA7 ATP8B2 DYNC1H1	8.43e-04	614	81	9	GO:0140657
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2G ATM	8.73e-04	11	81	2	GO:0016303
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA2 ABCA4 ATP6V0A4 ABCA7	1.01e-03	109	81	4	GO:0042626
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA2 ABCA4 ABCA7	1.04e-03	49	81	3	GO:0140359
GeneOntologyMolecularFunction	interleukin-1 binding	TRIM16 TRIM16L	1.04e-03	12	81	2	GO:0019966
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4A11 CYP4A22	1.23e-03	13	81	2	GO:0016713
GeneOntologyMolecularFunction	sodium channel activity	NALCN HCN3 PKD2L1	1.23e-03	52	81	3	GO:0005272
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 MYO9A DNAH8 DYNC1H1	1.36e-03	118	81	4	GO:0003774
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ABCA4 ATP8B2	1.43e-03	14	81	2	GO:0140333
GeneOntologyMolecularFunction	sulfotransferase activity	NDST1 GAL3ST2 HS3ST4	1.45e-03	55	81	3	GO:0008146
GeneOntologyMolecularFunction	arachidonate binding	CYP4A11 CYP4A22	1.65e-03	15	81	2	GO:0050544
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	NDST1 HS3ST4	1.65e-03	15	81	2	GO:0034483
GeneOntologyMolecularFunction	transcription corepressor binding	PHF1 CTBP1 CTBP2	1.78e-03	59	81	3	GO:0001222
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	CYP4A11 CTBP1 CTBP2 CYP4A22	1.78e-03	127	81	4	GO:0016616
GeneOntologyMolecularFunction	icosanoid binding	CYP4A11 CYP4A22	1.88e-03	16	81	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4A11 CYP4A22	1.88e-03	16	81	2	GO:0050543
GeneOntologyMolecularFunction	flippase activity	ABCA4 ATP8B2	2.12e-03	17	81	2	GO:0140327
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH-OH group of donors	CYP4A11 CTBP1 CTBP2 CYP4A22	2.41e-03	138	81	4	GO:0016614
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCA2 ABCA4 NALCN ATP6V0A4 HCN3 ORAI3 PKD2L1 SLC47A1 STRA6 ABCA7 SLC22A17 SLC29A4	2.76e-03	1180	81	12	GO:0022857
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH8 DYNC1H1	2.89e-03	70	81	3	GO:0003777
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA7 ATP8B2	2.94e-03	20	81	2	GO:0008525
GeneOntologyMolecularFunction	retinal binding	ABCA4 STRA6	3.25e-03	21	81	2	GO:0016918
GeneOntologyMolecularFunction	transferase activity, transferring sulphur-containing groups	NDST1 GAL3ST2 HS3ST4	3.39e-03	74	81	3	GO:0016782
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP4A11 CYP4A22	4.23e-03	24	81	2	GO:0008392
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C2G ATM	4.96e-03	26	81	2	GO:0052742
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	NALCN HCN3	4.96e-03	26	81	2	GO:0005248
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP4A11 CYP4A22	5.34e-03	27	81	2	GO:0008391
GeneOntologyMolecularFunction	long-chain fatty acid binding	CYP4A11 CYP4A22	5.74e-03	28	81	2	GO:0036041
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA2 ABCA4 ATP6V0A4 ABCA7	5.96e-03	178	81	4	GO:0015399
GeneOntologyMolecularFunction	nucleocytoplasmic carrier activity	IPO11 XPO7	7.45e-03	32	81	2	GO:0140142
GeneOntologyMolecularFunction	taste receptor activity	TAS2R42 PKD2L1	7.91e-03	33	81	2	GO:0008527
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	SLC47A1 SLC29A4	8.38e-03	34	81	2	GO:0042910
GeneOntologyMolecularFunction	aromatase activity	CYP4A11 CYP4A22	8.87e-03	35	81	2	GO:0070330
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA2 ABCA4 DNAH8 ABCA7 ATP8B2 DYNC1H1	9.04e-03	441	81	6	GO:0016887
GeneOntologyBiologicalProcess	lipid translocation	XKR7 ABCA2 ABCA4 XKR4 ABCA7 ATP8B2	1.19e-07	60	80	6	GO:0034204
GeneOntologyBiologicalProcess	regulation of membrane lipid distribution	XKR7 ABCA2 ABCA4 XKR4 ABCA7 ATP8B2	1.94e-07	65	80	6	GO:0097035
GeneOntologyBiologicalProcess	phospholipid translocation	XKR7 ABCA4 XKR4 ABCA7 ATP8B2	2.31e-06	55	80	5	GO:0045332
GeneOntologyBiologicalProcess	engulfment of apoptotic cell	XKR7 XKR4 ABCA7	2.47e-05	15	80	3	GO:0043652
GeneOntologyBiologicalProcess	organophosphate ester transport	XKR7 ABCA4 XKR4 ABCA7 ATP8B2 EPG5	3.98e-05	162	80	6	GO:0015748
GeneOntologyBiologicalProcess	lauric acid metabolic process	CYP4A11 CYP4A22	4.45e-05	3	80	2	GO:0048252
GeneOntologyBiologicalProcess	phospholipid transport	XKR7 ABCA4 XKR4 ABCA7 ATP8B2	5.77e-05	106	80	5	GO:0015914
GeneOntologyBiologicalProcess	phospholipid biosynthetic process	PIGL ABCA2 TMEM150A PIK3C2G DOLPP1 ATM MVD	8.18e-05	268	80	7	GO:0008654
GeneOntologyBiologicalProcess	retinol transport	ABCA4 STRA6	8.87e-05	4	80	2	GO:0034633
GeneOntologyBiologicalProcess	lipid transport	XKR7 ABCA2 ABCA4 CYP4A11 VPS13C STRA6 XKR4 ABCA7 ATP8B2	1.48e-04	506	80	9	GO:0006869
GeneOntologyBiologicalProcess	isoprenoid transport	ABCA4 STRA6	2.21e-04	6	80	2	GO:0046864
GeneOntologyBiologicalProcess	terpenoid transport	ABCA4 STRA6	2.21e-04	6	80	2	GO:0046865
GeneOntologyBiologicalProcess	positive regulation of retinoic acid receptor signaling pathway	TRIM16 CTBP2	2.21e-04	6	80	2	GO:0048386
GeneOntologyBiologicalProcess	lipid localization	XKR7 ABCA2 ABCA4 CYP4A11 VPS13C STRA6 XKR4 ABCA7 ATP8B2	3.35e-04	565	80	9	GO:0010876
GeneOntologyBiologicalProcess	membrane lipid biosynthetic process	CERS2 CERS5 PIGL ABCA2 GAL3ST2	3.64e-04	157	80	5	GO:0046467
Domain	ABC_A	ABCA2 ABCA4 ABCA7	1.56e-05	12	79	3	IPR026082
Domain	Dynein_HC_stalk	DNHD1 DNAH8 DYNC1H1	2.56e-05	14	79	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH8 DYNC1H1	2.56e-05	14	79	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH8 DYNC1H1	2.56e-05	14	79	3	PF08393
Domain	MT	DNHD1 DNAH8 DYNC1H1	2.56e-05	14	79	3	PF12777
Domain	DHC_fam	DNHD1 DNAH8 DYNC1H1	3.19e-05	15	79	3	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH8 DYNC1H1	3.19e-05	15	79	3	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH8 DYNC1H1	3.19e-05	15	79	3	PF03028
Domain	D_2_HYDROXYACID_DH_2	CTBP1 CTBP2	1.05e-04	4	79	2	PS00670
Domain	D_2_HYDROXYACID_DH_3	CTBP1 CTBP2	1.05e-04	4	79	2	PS00671
Domain	2-Hacid_dh_C	CTBP1 CTBP2	1.05e-04	4	79	2	PF02826
Domain	D-isomer_2_OHA_DH_cat_dom	CTBP1 CTBP2	1.05e-04	4	79	2	IPR006139
Domain	D-isomer_DH_CS	CTBP1 CTBP2	1.05e-04	4	79	2	IPR029753
Domain	2-Hacid_dh	CTBP1 CTBP2	1.05e-04	4	79	2	PF00389
Domain	D_2_HYDROXYACID_DH_1	CTBP1 CTBP2	1.05e-04	4	79	2	PS00065
Domain	D-isomer_DH_NAD-bd	CTBP1 CTBP2	1.75e-04	5	79	2	IPR006140
Domain	Lag1/Lac1	CERS2 CERS5	2.62e-04	6	79	2	IPR016439
Domain	AAA+_ATPase	ABCA2 ABCA4 DNAH8 ABCA7 DYNC1H1	3.62e-04	144	79	5	IPR003593
Domain	AAA	ABCA2 ABCA4 DNAH8 ABCA7 DYNC1H1	3.62e-04	144	79	5	SM00382
Domain	DHC_N1	DNAH8 DYNC1H1	4.87e-04	8	79	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH8 DYNC1H1	4.87e-04	8	79	2	IPR013594
Domain	ABC_transporter_CS	ABCA2 ABCA4 ABCA7	7.42e-04	42	79	3	IPR017871
Domain	XK_rel	XKR7 XKR4	9.48e-04	11	79	2	IPR018629
Domain	XK-related	XKR7 XKR4	9.48e-04	11	79	2	PF09815
Domain	ABC_tran	ABCA2 ABCA4 ABCA7	1.10e-03	48	79	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA2 ABCA4 ABCA7	1.10e-03	48	79	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCA2 ABCA4 ABCA7	1.17e-03	49	79	3	PS00211
Domain	ABC_transporter-like	ABCA2 ABCA4 ABCA7	1.24e-03	50	79	3	IPR003439
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DYNC1H1	1.56e-03	14	79	2	IPR024317
Domain	IMPORTIN_B_NT	IPO11 XPO7	1.56e-03	14	79	2	PS50166
Domain	AAA_8	DNAH8 DYNC1H1	1.56e-03	14	79	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH8 DYNC1H1	1.56e-03	14	79	2	IPR011704
Domain	AAA_5	DNAH8 DYNC1H1	1.56e-03	14	79	2	PF07728
Domain	IBN_N	IPO11 XPO7	1.79e-03	15	79	2	PF03810
Domain	PI3/4_kinase_CS	PIK3C2G ATM	1.79e-03	15	79	2	IPR018936
Domain	TLC	CERS2 CERS5	2.04e-03	16	79	2	PS50922
Domain	TLC	CERS2 CERS5	2.04e-03	16	79	2	SM00724
Domain	-	PIK3C2G ATM	2.04e-03	16	79	2	1.10.1070.11
Domain	IBN_N	IPO11 XPO7	2.04e-03	16	79	2	SM00913
Domain	TRAM_LAG1_CLN8	CERS2 CERS5	2.04e-03	16	79	2	PF03798
Domain	TLC-dom	CERS2 CERS5	2.04e-03	16	79	2	IPR006634
Domain	PI3Kc	PIK3C2G ATM	2.04e-03	16	79	2	SM00146
Domain	Importin-beta_N	IPO11 XPO7	2.31e-03	17	79	2	IPR001494
Domain	PI3/4_kinase_cat_dom	PIK3C2G ATM	2.59e-03	18	79	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C2G ATM	2.59e-03	18	79	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C2G ATM	2.59e-03	18	79	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C2G ATM	2.59e-03	18	79	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C2G ATM	2.59e-03	18	79	2	PS00916
Domain	P-loop_NTPase	DNHD1 NDST1 ABCA2 ABCA4 MYO9A GAL3ST2 HS3ST4 DNAH8 ABCA7 DYNC1H1	2.98e-03	848	79	10	IPR027417
Domain	TIR	IL18RAP TLR8	3.52e-03	21	79	2	SM00255
Domain	TIR	IL18RAP TLR8	3.86e-03	22	79	2	PF01582
Domain	IGv	DSCAML1 MOG CD200	3.95e-03	75	79	3	SM00406
Domain	-	IL18RAP TLR8	4.22e-03	23	79	2	3.40.50.10140
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ABCA2 TBC1D4 CADPS2 CLSTN1 TRIP12 DSCAML1	7.24e-07	130	83	6	12421765
Pubmed	ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.	CTBP1 CTBP2 ATM	7.28e-07	8	83	3	25086746
Pubmed	Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.	CYP4A11 CYP4A22	5.63e-06	2	83	2	15611369
Pubmed	CTBP1 and CTBP2 mutations underpinning neurological disorders: a systematic review.	CTBP1 CTBP2	5.63e-06	2	83	2	36331689
Pubmed	Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions.	CARMIL2 TXNRD3	5.63e-06	2	83	2	15588584
Pubmed	20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.	CYP4A11 CYP4A22	5.63e-06	2	83	2	23825080
Pubmed	Differential spatial expression and subcellular localization of CtBP family members in rodent brain.	CTBP1 CTBP2	5.63e-06	2	83	2	22745816
Pubmed	Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.	CYP4A11 CYP4A22	5.63e-06	2	83	2	16691295
Pubmed	The P450 gene superfamily: recommended nomenclature.	CYP4A11 CYP4A22	5.63e-06	2	83	2	3829886
Pubmed	Cryo-EM structure of CtBP2 confirms tetrameric architecture.	CTBP1 CTBP2	5.63e-06	2	83	2	33264605
Pubmed	C-Terminal Binding Protein is Involved in Promoting to the Carcinogenesis of Human Glioma.	CTBP1 CTBP2	5.63e-06	2	83	2	27699603
Pubmed	Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.	CYP4A11 CYP4A22	5.63e-06	2	83	2	29277328
Pubmed	Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.	CYP4A11 CYP4A22	5.63e-06	2	83	2	21820496
Pubmed	Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.	CYP4A11 CYP4A22	5.63e-06	2	83	2	23641057
Pubmed	Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.	TRIM16 TRIM16L	5.63e-06	2	83	2	23341783
Pubmed	The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation.	TRIM16 TRIM16L	5.63e-06	2	83	2	11919186
Pubmed	Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.	CYP4A11 CYP4A22	5.63e-06	2	83	2	20943934
Pubmed	The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.	CYP4A11 CYP4A22	5.63e-06	2	83	2	28912346
Pubmed	Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.	CYP4A11 CYP4A22	5.63e-06	2	83	2	24413902
Pubmed	Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.	CTBP1 CTBP2	5.63e-06	2	83	2	7479821
Pubmed	The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.	CYP4A11 CYP4A22	5.63e-06	2	83	2	2766933
Pubmed	Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.	CTBP1 CTBP2	5.63e-06	2	83	2	24657618
Pubmed	Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1.	TRIM16 TRIM16L	5.63e-06	2	83	2	34146477
Pubmed	CtBPs promote cell survival through the maintenance of mitotic fidelity.	CTBP1 CTBP2	5.63e-06	2	83	2	19506021
Pubmed	Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.	CYP4A11 CYP4A22	5.63e-06	2	83	2	8031839
Pubmed	Assembly of human C-terminal binding protein (CtBP) into tetramers.	CTBP1 CTBP2	5.63e-06	2	83	2	29700119
Pubmed	Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.	TRIM16 TRIM16L	5.63e-06	2	83	2	31342168
Pubmed	Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.	CYP4A11 CYP4A22	5.63e-06	2	83	2	10860550
Pubmed	NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).	CTBP1 CTBP2	5.63e-06	2	83	2	33524397
Pubmed	The E3 Ligase TRIM16 Is a Key Suppressor of Pathological Cardiac Hypertrophy.	TRIM16 TRIM16L	5.63e-06	2	83	2	35437018
Pubmed	Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.	CTBP1 CTBP2	5.63e-06	2	83	2	20964627
Pubmed	Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.	CYP4A11 CYP4A22	5.63e-06	2	83	2	17112342
Pubmed	Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.	CYP4A11 CYP4A22	5.63e-06	2	83	2	11320253
Pubmed	NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2.	CTBP1 CTBP2	5.63e-06	2	83	2	34997967
Pubmed	TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.	TRIM16 TRIM16L	5.63e-06	2	83	2	32251645
Pubmed	Characterization of the CYP4A11 gene, a second CYP4A gene in humans.	CYP4A11 CYP4A22	5.63e-06	2	83	2	12464262
Pubmed	A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.	CTBP1 CTBP2	5.63e-06	2	83	2	9479502
Pubmed	High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.	CYP4A11 CYP4A22	5.63e-06	2	83	2	30088983
Pubmed	Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.	CYP4A11 CYP4A22	5.63e-06	2	83	2	15066132
Pubmed	Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.	CTBP1 CTBP2	5.63e-06	2	83	2	10364211
Pubmed	CtBP, an unconventional transcriptional corepressor in development and oncogenesis.	CTBP1 CTBP2	5.63e-06	2	83	2	11864595
Pubmed	Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.	CYP4A11 CYP4A22	5.63e-06	2	83	2	19208908
Pubmed	A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.	PHF1 CTBP1 CTBP2	1.04e-05	18	83	3	29628311
Pubmed	Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells.	CTBP1 CTBP2	1.69e-05	3	83	2	26871283
Pubmed	MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.	CTBP1 CTBP2	1.69e-05	3	83	2	25728771
Pubmed	Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.	CYP4A11 CYP4A22	1.69e-05	3	83	2	2354437
Pubmed	Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins.	CTBP1 CTBP2	1.69e-05	3	83	2	11328817
Pubmed	Calsenilin interacts with transcriptional co-repressor C-terminal binding protein(s).	CTBP1 CTBP2	1.69e-05	3	83	2	16787403
Pubmed	A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.	CTBP1 CTBP2	1.69e-05	3	83	2	16762039
Pubmed	Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.	CYP4A11 CYP4A22	1.69e-05	3	83	2	8011168
Pubmed	EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.	CTBP1 ATM	1.69e-05	3	83	2	29939287
Pubmed	APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC.	CTBP1 CTBP2	1.69e-05	3	83	2	21665989
Pubmed	Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.	CTBP1 CTBP2	1.69e-05	3	83	2	14736873
Pubmed	Eleven residues determine the acyl chain specificity of ceramide synthases.	CERS2 CERS5	1.69e-05	3	83	2	29632068
Pubmed	Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells.	CERS2 CERS5	1.69e-05	3	83	2	20406683
Pubmed	Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.	CYP4A11 CYP4A22	1.69e-05	3	83	2	28270609
Pubmed	The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.	CYP4A11 CYP4A22	1.69e-05	3	83	2	1991046
Pubmed	Accumulation of advanced glycation end products promotes atrophic nonunion incidence in mice through a CtBP1/2-dependent mechanism.	CTBP1 CTBP2	1.69e-05	3	83	2	37696386
Pubmed	C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins.	CTBP1 CTBP2	1.69e-05	3	83	2	9858600
Pubmed	Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.	ABCA4 ABCA7	1.69e-05	3	83	2	24097981
Pubmed	Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.	CYP4A11 CYP4A22	1.69e-05	3	83	2	19713718
Pubmed	Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver.	CYP4A11 CYP4A22	1.69e-05	3	83	2	15313227
Pubmed	HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells.	CTBP1 CTBP2	1.69e-05	3	83	2	12711682
Pubmed	H19/Mir-130b-3p/Cyp4a14 potentiate the effect of praziquantel on liver in the treatment of Schistosoma japonicum infection.	CYP4A11 CYP4A22	1.69e-05	3	83	2	37659685
Pubmed	Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.	CTBP1 CTBP2	1.69e-05	3	83	2	18184656
Pubmed	TRIM16 exerts protective function on myocardial ischemia/reperfusion injury through reducing pyroptosis and inflammation via NLRP3 signaling.	TRIM16 TRIM16L	1.69e-05	3	83	2	36208489
Pubmed	CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling.	CTBP1 CTBP2	1.69e-05	3	83	2	30442980
Pubmed	ZEB represses transcription through interaction with the corepressor CtBP.	CTBP1 CTBP2	1.69e-05	3	83	2	10359772
Pubmed	A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.	CYP4A11 CYP4A22	1.69e-05	3	83	2	9271096
Pubmed	Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription.	CTBP1 CTBP2	3.37e-05	4	83	2	12867035
Pubmed	Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1.	CTBP1 CTBP2	3.37e-05	4	83	2	10567582
Pubmed	The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.	CTBP1 CTBP2	3.37e-05	4	83	2	12444977
Pubmed	Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.	CYP4A11 CYP4A22	3.37e-05	4	83	2	8334987
Pubmed	Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.	CTBP1 CTBP2	3.37e-05	4	83	2	35800763
Pubmed	Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis.	CTBP1 CTBP2	3.37e-05	4	83	2	18391014
Pubmed	Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene.	CTBP1 CTBP2	3.37e-05	4	83	2	15542832
Pubmed	Mapping of the azh locus to mouse chromosome 4.	CYP4A11 CYP4A22	3.37e-05	4	83	2	1552159
Pubmed	Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats.	CYP4A11 CYP4A22	3.37e-05	4	83	2	10049703
Pubmed	C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.	CTBP1 CTBP2	3.37e-05	4	83	2	19564408
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	DNAH8 DYNC1H1	3.37e-05	4	83	2	15762842
Pubmed	Differences in metabolite burden of di(2-ethylhexyl)phthalate in pregnant and postpartum dams and their offspring in relation to drug-metabolizing enzymes in mice.	CYP4A11 CYP4A22	3.37e-05	4	83	2	22159897
Pubmed	HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.	CTBP1 CTBP2	3.37e-05	4	83	2	19486893
Pubmed	Salt modulates vascular response through adenosine A(2A) receptor in eNOS-null mice: role of CYP450 epoxygenase and soluble epoxide hydrolase.	CYP4A11 CYP4A22	3.37e-05	4	83	2	21161333
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	ABCA4 DNAH8 EPG5	3.68e-05	27	83	3	18649358
Pubmed	Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.	CTBP1 CTBP2	5.60e-05	5	83	2	16702210
Pubmed	Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs.	CYP4A11 CYP4A22	5.60e-05	5	83	2	8363569
Pubmed	PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels.	CERS2 CERS5	5.60e-05	5	83	2	38961186
Pubmed	HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.	CTBP1 CTBP2	5.60e-05	5	83	2	16724116
Pubmed	Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.	CERS2 CERS5	5.60e-05	5	83	2	26887952
Pubmed	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.	CTBP1 CTBP2	5.60e-05	5	83	2	18483224
Pubmed	hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.	CTBP1 CTBP2	5.60e-05	5	83	2	10438528
Pubmed	Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.	CERS2 CERS5	5.60e-05	5	83	2	15823095
Pubmed	Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor.	CTBP1 CTBP2	5.60e-05	5	83	2	10764811
Pubmed	Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.	CYP4A11 CYP4A22	5.60e-05	5	83	2	20427718
Pubmed	Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35.	CYP4A11 CYP4A22	5.60e-05	5	83	2	7601480
Pubmed	Organization of the distal end of mouse chromosome 4.	CYP4A11 CYP4A22	8.39e-05	6	83	2	3166417
Pubmed	Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism.	CYP4A11 CYP4A22	8.39e-05	6	83	2	28007964
Pubmed	PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions.	CTBP1 CTBP2	8.39e-05	6	83	2	17546044
Pubmed	Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.	ABCA4 ABCA7	8.39e-05	6	83	2	12111378
Pubmed	Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.	CERS2 CERS5	8.39e-05	6	83	2	23936132
Interaction	TTYH1 interactions	CERS2 CERS5 ABCA2 MYO9A FKRP HCN3 SLC47A1 ABCA7 ATP8B2	2.12e-06	300	77	9	int:TTYH1
Interaction	SCN2B interactions	COG2 EIF2B4 ATM IPO11 XPO7	3.16e-05	95	77	5	int:SCN2B
Interaction	LCOR interactions	PHF1 NDST1 ABCA2 CTBP1 CTBP2 ATM TRIP12	3.88e-05	242	77	7	int:LCOR
Interaction	CYP4A22 interactions	CYP4A11 CYP4A22	4.31e-05	3	77	2	int:CYP4A22
Interaction	CEP68 interactions	COG2 CTBP1 CTBP2	5.83e-05	20	77	3	int:CEP68
GeneFamily	ATP binding cassette subfamily A	ABCA2 ABCA4 ABCA7	7.53e-06	14	51	3	805
GeneFamily	CERS class homeoboxes	CERS2 CERS5	1.16e-04	6	51	2	530
GeneFamily	Sulfotransferases, membrane bound	NDST1 GAL3ST2 HS3ST4	1.54e-04	37	51	3	763
GeneFamily	Blood group antigens\|XK related family	XKR7 XKR4	4.22e-04	11	51	2	955
GeneFamily	Immunoglobulin like domain containing	AMIGO3 IL18RAP DSCAML1 CD200	2.13e-03	193	51	4	594
GeneFamily	Cytochrome P450 family 4	CYP4A11 CYP4A22	4.62e-03	36	51	2	1003
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK CFAP54 TBC1D4 MYO9A XKR4 DSCAML1 CD200	5.80e-08	188	82	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 HCN3 GAL3ST2 STRA6 GPR132 DSCAML1	7.87e-07	172	82	6	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 HCN3 GAL3ST2 STRA6 GPR132 DSCAML1	7.87e-07	172	82	6	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA4 NALCN PIK3C2G TMEM255B CD200 IPO11	1.20e-06	185	82	6	241ea1e178fffef9e7df971de739e794332d5173
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PXMP4 CFAP54 FKRP ANKDD1B ABCA7	8.55e-06	150	82	5	b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK TBC1D4 ANKDD1B IL18RAP ITIH1	1.40e-05	166	82	5	c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK TBC1D4 ANKDD1B IL18RAP ITIH1	1.40e-05	166	82	5	0975fc165bcc7e85f053d9d0244fffe407c23571
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D4 HCN3 GAL3ST2 STRA6 DSCAML1	1.66e-05	172	82	5	48d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 TBC1D4 MYO9A DSCAML1 CD200	1.85e-05	176	82	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	AMIGO3 HCN3 SLC29A4 PLXNB1	2.13e-05	88	82	4	1ca0e16981e88030987412e12838a9797b97b9c9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 TBC1D4 MYO9A DSCAML1 CD200	2.23e-05	183	82	5	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	TNIK TBC1D4 ANKDD1B DSCAML1 ATP8B2	2.29e-05	184	82	5	22c15ce30171c687ab564f4383ae74d38b759272
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	STK33 PTH2 PKD2L1 TMEM255B	2.32e-05	90	82	4	3817a5b0235e632d976ea565175bdbebbd959bf0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	STK33 PTH2 PKD2L1 TMEM255B	2.32e-05	90	82	4	a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 TBC1D4 MYO9A XKR4 CD200	2.41e-05	186	82	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 ABCA4 MYO9A XKR4 DSCAML1	2.41e-05	186	82	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	COPD-Myeloid-DC_Mature\|COPD / Disease state, Lineage and Cell class	TBC1D4 GPR132 DSCAML1 ITIH1 CD200	2.54e-05	188	82	5	de93ccb53edb8599da9e312db0e3af604c21f673
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A STK33 XKR4 DSCAML1	2.54e-05	188	82	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A XKR4 DSCAML1 CD200	2.60e-05	189	82	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NALCN PXDC1 TMEM255B DSCAML1 CD200	2.67e-05	190	82	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 TBC1D4 MYO9A XKR4 DSCAML1	2.74e-05	191	82	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	COPD-Myeloid-DC_Mature\|Myeloid / Disease state, Lineage and Cell class	TBC1D4 GPR132 DSCAML1 ITIH1 CD200	2.81e-05	192	82	5	baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PXMP4 SZT2 ATP8B2 SLC22A17	2.88e-05	95	82	4	3d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	VPS13C OAS3 ATM TRIP12 DYNC1H1	3.41e-05	200	82	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AMIGO3 HCN3 SLC29A4 PLXNB1	3.52e-05	100	82	4	cb0deaf1c33d2789417e93cc01d94e34a611d20a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A DSCAML1 CD200	1.07e-04	133	82	4	f303ab771482281d8793974f9f5279cee09431fe
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PXMP4 PIGL SZT2 ATP8B2	1.10e-04	134	82	4	72d7eec3aeb43319f3ef81bb5518fae8d8880136
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 MYO9A DSCAML1 CD200	1.41e-04	143	82	4	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PXMP4 CFAP54 FKRP ANKDD1B	1.45e-04	144	82	4	57d2846ec26d4490ec11c171af447b17a729437e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G STK33 ATP6V0A4 CADPS2	1.53e-04	146	82	4	e887e9de895fd453faa703997ef372cc6410fc49
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G ATP6V0A4 CADPS2 DSCAML1	1.70e-04	150	82	4	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	Control-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	ATP6V0A4 PKD2L1 XKR4 MOG	1.92e-04	155	82	4	4b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	BNC1 GAL3ST2 DSCAML1 CD200	1.97e-04	156	82	4	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	TBC1D4 CYP4A11 DNAH8 CD200	2.02e-04	157	82	4	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	IPF-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	TBC1D4 ATP6V0A4 PKD2L1 XKR4	2.07e-04	158	82	4	67adf625a959444762d32268b3b7441f6f8b3b8c
ToppCell	Control-Lymphocyte-T_NK-Treg\|Control / Disease, Lineage and Cell Type	TRIM16 TBC1D4 DNAH8 ATP8B2	2.07e-04	158	82	4	260dc209f619e1d17a11cede979636001c749786
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tregs\|Lung / Manually curated celltypes from each tissue	TBC1D4 DNAH8 SLC29A4 CD200	2.07e-04	158	82	4	f433bc189f000efa34e8e09ab32b3fa22bcf64c4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G ATP6V0A4 CADPS2 DSCAML1	2.44e-04	165	82	4	9bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIM16 TNIK TBC1D4 ATP8B2	2.44e-04	165	82	4	dbe231d00843cae917efd1abea6079ace3b45cdf
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRIM16 TNIK TBC1D4 ATP8B2	2.44e-04	165	82	4	9ccce713d4122054bf4bef4a7126d90cf9141b84
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NALCN TMEM255B CD200 IPO11	2.50e-04	166	82	4	941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCell	mild-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TBC1D4 ANKDD1B DNAH8 ATP8B2	2.50e-04	166	82	4	f8f8423423d72f0ea0266b59126abb27beb23094
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NALCN TMEM255B CD200 IPO11	2.50e-04	166	82	4	6f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCell	COVID-19_Moderate-Treg\|COVID-19_Moderate / disease group, cell group and cell class	TRIM16 IL11 TBC1D4 ATP8B2	2.56e-04	167	82	4	4ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XKR7 TBC1D4 GAL3ST2 DSCAML1	2.61e-04	168	82	4	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A DSCAML1 CD200	2.74e-04	170	82	4	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NDST1 CTBP2 ATM IL18RAP	2.74e-04	170	82	4	81341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	CYP4A11 AMDHD1 ITIH1 CYP4A22	2.99e-04	174	82	4	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC1 ABCA4 ATP6V0A4 CD200	3.05e-04	175	82	4	59249c9e83952d7277010e7be3c779e26399eb5d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XKR7 TBC1D4 GAL3ST2 DSCAML1	3.05e-04	175	82	4	91cb819a1786020713b7e64480de0545380daae9
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC1 ABCA4 ATP6V0A4 CD200	3.05e-04	175	82	4	b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TBC1D4 EIF2B4 PLXNB1 CD200	3.12e-04	176	82	4	56c055488e34605d32562571a2fee621b47c9441
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 MYO9A VPS13C TLR8	3.12e-04	176	82	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM16 BNC1 ABCA2 CADPS2	3.19e-04	177	82	4	a235ff4f37a7622216526191efc4832fb8ed6957
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC1 NALCN HS3ST4 TMEM255B	3.19e-04	177	82	4	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	XKR7 TBC1D4 GAL3ST2 DSCAML1	3.19e-04	177	82	4	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC1 NALCN HS3ST4 TMEM255B	3.19e-04	177	82	4	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A DSCAML1 CD200	3.19e-04	177	82	4	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC1 NALCN HS3ST4 TMEM255B	3.19e-04	177	82	4	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA2 PIK3C2G ATP6V0A4 PLXNB1	3.19e-04	177	82	4	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G STK33 ATP6V0A4 CADPS2	3.19e-04	177	82	4	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A DSCAML1 CD200	3.26e-04	178	82	4	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP54 MYO9A XKR4 DSCAML1	3.26e-04	178	82	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 HS3ST4 CADPS2	3.26e-04	178	82	4	731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA4 NALCN PIK3C2G CD200	3.33e-04	179	82	4	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	facs-Lung-EPCAM-24m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 HCN3 GPR132 DSCAML1	3.33e-04	179	82	4	51872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 HCN3 GPR132 DSCAML1	3.33e-04	179	82	4	1b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 CTBP2 CADPS2	3.40e-04	180	82	4	b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 CTBP2 CADPS2	3.40e-04	180	82	4	f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 TBC1D4 MYO9A DSCAML1	3.47e-04	181	82	4	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 HS3ST4 CADPS2	3.47e-04	181	82	4	6e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	TBC1D4 ATP6V0A4 PKD2L1 MVD	3.47e-04	181	82	4	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A DSCAML1 CD200	3.47e-04	181	82	4	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G STK33 ATP6V0A4 CADPS2	3.47e-04	181	82	4	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A DSCAML1 CD200	3.47e-04	181	82	4	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	COPD-Myeloid-DC_Mature\|World / Disease state, Lineage and Cell class	TBC1D4 GPR132 ITIH1 CD200	3.47e-04	181	82	4	675603a401d92cf9fdcd44e211ec899fa86a0d49
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 MYO9A DSCAML1 CD200	3.47e-04	181	82	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 NALCN XKR4 CD200	3.47e-04	181	82	4	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 NALCN XKR4 CD200	3.47e-04	181	82	4	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 TBC1D4 DSCAML1 CD200	3.54e-04	182	82	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TBC1D4 CARMIL2 OAS3 ATP8B2	3.54e-04	182	82	4	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	TBC1D4 CARMIL2 OAS3 ATP8B2	3.54e-04	182	82	4	877b6e611626628e709568747512f2827ebb2795
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A DSCAML1 CD200	3.54e-04	182	82	4	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TBC1D4 CARMIL2 OAS3 ATP8B2	3.54e-04	182	82	4	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBC1D4 CARMIL2 OAS3 ATP8B2	3.54e-04	182	82	4	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBC1D4 CARMIL2 OAS3 ATP8B2	3.54e-04	182	82	4	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A DSCAML1 CD200	3.62e-04	183	82	4	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 HS3ST4 CADPS2	3.62e-04	183	82	4	b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	TBC1D4 CARMIL2 OAS3 ATP8B2	3.62e-04	183	82	4	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G STK33 ATP6V0A4 CADPS2	3.62e-04	183	82	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3C2G TMEM255B CD200 IPO11	3.62e-04	183	82	4	a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 PKD2L1 HS3ST4 CADPS2	3.62e-04	183	82	4	274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3C2G TMEM255B CD200 IPO11	3.62e-04	183	82	4	13ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA4 NALCN TMEM255B CD200	3.62e-04	183	82	4	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	Immune_cells-large_pre-B.\|World / Lineage and Cell class	TRIM16 CARMIL2 TXNRD3 EPG5	3.62e-04	183	82	4	81b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D4 MYO9A XKR4 DSCAML1	3.69e-04	184	82	4	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	E12.5-Endothelial-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRIM16 ABCA4 TMEM255B CD200	3.77e-04	185	82	4	e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PTH2 IL18RAP SLC29A4 MVD	3.77e-04	185	82	4	3b2da51aec057b462749ae39afb8f253afcf38d5
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA4 NALCN TMEM255B CD200	3.77e-04	185	82	4	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	E12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRIM16 ABCA4 TMEM255B CD200	3.77e-04	185	82	4	0bccc424d0466f7f82baa00127c733640a2d50fb
Disease	autoimmune disease (implicated_via_orthology)	GPR132 CD200	4.45e-05	4	81	2	DOID:417 (implicated_via_orthology)
Disease	X-14939 measurement	CYP4A11 CYP4A22	1.11e-04	6	81	2	EFO_0800747
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	CYP4A11 CYP4A22	4.03e-04	11	81	2	DOID:0110861 (biomarker_via_orthology)
Disease	Malformations of Cortical Development	NDST1 DYNC1H1	6.63e-04	14	81	2	C1955869
Disease	Cortical Dysplasia	NDST1 DYNC1H1	6.63e-04	14	81	2	C0431380
Disease	visfatin measurement	HS3ST4 GRAMD4	9.85e-04	17	81	2	EFO_0801230
Disease	Osteoarthritis of hip	IL11 ITIH1	1.37e-03	20	81	2	C0029410
Disease	Arthrogryposis	MYO9A DYNC1H1	1.51e-03	21	81	2	C0003886
Disease	brain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement	HS3ST4 SLC29A4	1.66e-03	22	81	2	EFO_0004277, EFO_0006790, EFO_0006792, EFO_0006797, EFO_0006798
Disease	Immunologic Deficiency Syndromes	ATM EPG5	1.81e-03	23	81	2	C0021051
Disease	lymphocyte count	TNIK CERS5 BNC1 CARMIL2 PKD2L1 SLC47A1 ATM CLSTN1 IL18RAP TRIP12 MOG	2.15e-03	1464	81	11	EFO_0004587
Disease	glucose tolerance test	TBC1D4 VPS13C	2.50e-03	27	81	2	EFO_0004307

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQRLLIYRWAHQALV	EPG5	1286	Q9HCE0
ISLNAREYFNIHLWL	CFAP54	2371	Q96N23
HLETQVWAAYLLERL	ERVK11-1	41	P61568
ILNLYRRATWLHQAL	CTBP1	136	Q13363
HILNLYRRNTWLYQA	CTBP2	141	P56545
LLTLLVQRHFFLSQW	ABCA4	1891	P78363
NHVLALLRWRAYLLH	CARMIL2	41	Q6F5E8
RLSLNYLIARGWRIQ	GRAMD4	261	Q6IC98
QILHALDWTLQDYIR	BNC1	126	Q01954
LIKAVQLYLHRQWLL	CYP4A11	31	Q02928
QLYLHRQWLLKALQQ	CYP4A11	36	Q02928
VLHLLRYRNWHARSL	CLSTN1	771	O94985
YWEARQLRLLNFILH	DNHD1	1161	Q96M86
RLYHLLQRWHQRGLS	AMIGO3	226	Q86WK7
FINSLKHRLLVYLWR	DET1	291	Q7L5Y6
VLQLLHIFWAYLILR	CERS2	311	Q96G23
QLLHVIWSYLIARIA	CERS5	321	Q8N5B7
LVSRALQLLAEHRFW	ABCA7	421	Q8IZY2
FLQRLLLVHGRWSYL	ATP8B2	871	P98198
RSLQSIQVAHRLYWL	PIK3C2G	781	O75747
IQVAHRLYWLLKNAE	PIK3C2G	786	O75747
ASQHSLRALSWRRLY	ORAI3	41	Q9BRQ5
LVAVLAASALLYRHW	IL18RAP	371	O95256
NNARFLDLLWRHVLS	DOLPP1	126	Q86YN1
HVERLWAYLTIQELL	ITIH1	561	P19827
NHTLDINVRWLAVLY	IPO11	51	Q9UI26
RLRADLLSYLRHVQW	IL11	96	P20809
LANYLRLQQVLSWAR	PNMA6E	446	A0A0J9YXQ4
VQGLWRRLNTLQHYK	PLXNB1	1826	O43157
AWIREISQLHYALQA	DNAH8	571	Q96JB1
IERWLSAYHANQILV	NDST1	761	P52848
YLNAISWRIIHLVHR	MVD	276	P53602
LLRLSRLIRYIHQWE	HCN3	221	Q9P1Z3
WQNHASLRLLNLVYD	EIF2B4	476	Q9UI10
LVALIICYNWLHRRL	MOG	221	Q16653
VLISILLYWKRHRNQ	CD200	251	P41217
RLYEHFNRTLWAQLR	GAL3ST2	281	Q9H3Q3
TLLYIWTQHRLNDSL	ATM	261	Q13315
RIAHLNRGQQYLLWV	DSCAML1	1251	Q8TD84
LIKAAQLYLHRQWLL	CYP4A22	31	Q5TCH4
QLYLHRQWLLKALQQ	CYP4A22	36	Q5TCH4
HLRWLQQYVAELRLH	ABCA2	511	Q9BZC7
VWLTDRLDLQLHIYQ	CADPS2	1216	Q86UW7
LIIINSSRWEHLIYQ	AMDHD1	391	Q96NU7
FLLAWFHAIIQERLR	DYNC1H1	4181	Q14204
HRLWRLTLQILARYS	COG2	441	Q14746
LNLLVLFYVSWLQHQ	FKRP	16	Q9H9S5
AIQLYRHGTSLEIWL	PIWIL3	251	Q7Z3Z3
IRIGIYALHLENWLQ	HS3ST4	331	Q9Y661
LILLVKHWYRQVAAQ	OAS3	601	Q9Y6K5
RLQLRWVDVAHLVLY	PHF1	246	O43189
YIRNQHRWTLGLLAC	GPR132	101	Q9UNW8
LRQTAVRLLWHLRNY	TAS2R42	291	Q7RTR8
ALAWYLRQNLLIFLH	SZT2	2236	Q5T011
LYLHRSLADLGRLWQ	PXDC1	51	Q5TGL8
RWIIQSLASAIAYLH	STK33	216	Q9BYT3
LRYGQLLEQSRHSWV	TMEM150A	96	Q86TG1
HLYRLLWASAVLNVL	TMEM255B	191	Q8WV15
ASLLNYRNIWKNLLI	SLC22A17	296	Q8WUG5
HRSQLLWFRRLYIIF	PIGL	226	Q9Y2B2
LKALNLHSLYRARWT	SHLD3	156	Q6ZNX1
WALFLNTQHILLLFR	SLC47A1	131	Q96FL8
WRVLLSALYNAIHLG	STRA6	531	Q9BX79
RTLLWDLAYHQLKAN	ANKDD1B	426	A6NHY2
ISRLINLKNLYLAWN	TLR8	166	Q9NR97
RVYYLSWLRNRILHN	TNIK	1111	Q9UKE5
HLLQLGQVWRYLRAL	XKR7	186	Q5GH72
RLLAALERRHWLNSY	PTH2	76	Q96A98
ILYSWDLRSYQRLHQ	TLE7	311	A0A1W2PR48
RTARQALLTQHYRWA	UAP1L1	421	Q3KQV9
QSLIHILQLGQIWRY	XKR4	256	Q5GH76
HQRSLRARLYWLQVD	VPS13C	3196	Q709C8
IHRLRYLSSIWNILD	PKD2L1	376	Q9P0L9
EIWQFLALQYRLRHR	TBC1D4	926	O60343
YLRLWALSLAHAQLS	ATP6V0A4	741	Q9HBG4
SVHYLLSLWQRLAAS	XPO7	376	Q9UIA9
NHISSLNWGYRLSLR	TXNRD3	251	Q86VQ6
RFLHWRQVLSQQSLY	TRIM16	411	O95361
ALLLHRYVVARVIWA	SLC29A4	341	Q7RTT9
SNVWHLYALASVLQR	VRTN	171	Q9H8Y1
VILLLRVLHAISRYW	TRIP12	1471	Q14669
AILQATYIHSWNLAR	PXMP4	66	Q9Y6I8
FLHWRQVLSQQSLYL	TRIM16L	196	Q309B1
HNVYIFSLKLNQWRL	KLHL38	351	Q2WGJ6
LLSYNDLRHFQIIWN	NALCN	1461	Q8IZF0
LQASWRAHLERQRYL	MYO9A	1081	B2RTY4