Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ank_2	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	4.90e-08	215	134	12	PF12796
Domain	Ank	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	9.32e-08	228	134	12	PF00023
Domain	-	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	2.32e-07	248	134	12	1.25.40.20
Domain	ANK	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	2.64e-07	251	134	12	SM00248
Domain	ANK_REPEAT	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	2.87e-07	253	134	12	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	3.00e-07	254	134	12	IPR020683
Domain	ANK_REP_REGION	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	3.00e-07	254	134	12	PS50297
Domain	Ankyrin_rpt	ANKK1 ANKRD29 ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	4.18e-07	262	134	12	IPR002110
Domain	ARM-like	RIPOR3 TRIP12 XPO5 INSC NBEAL2 IPO13 ZER1 STKLD1 GCN1 NIPBL	2.55e-05	270	134	10	IPR011989
Domain	RECEPTOR_TYR_KIN_V_2	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	IPR001426
Domain	EphA2_TM	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	IPR001090
Domain	Eph_TM	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	IPR027936
Domain	EPH_lbd	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	SM00615
Domain	Ephrin_lbd	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	IPR016257
Domain	EPH_LBD	EPHB2 EPHA3 EPHA4	1.24e-04	14	134	3	PS51550
Domain	ARM-type_fold	TRIP12 RYR3 XPO5 INSC NBEAL2 IPO13 ZER1 STKLD1 GCN1 NIPBL	1.70e-04	339	134	10	IPR016024
Domain	-	EPHB2 ZZEF1 HERC2 EPHA3 EPHA4	1.79e-04	73	134	5	2.60.120.260
Domain	SAM/pointed	EPHB2 STARD13 KIDINS220 ANKS3 EPHA3 EPHA4	1.99e-04	117	134	6	IPR013761
Domain	-	RIPOR3 TRIP12 XPO5 INSC IPO13 ZER1 GCN1 NIPBL	2.03e-04	222	134	8	1.25.10.10
Domain	KASH	SYNE1 SYNE2	3.04e-04	4	134	2	IPR012315
Domain	KASH	SYNE1 SYNE2	3.04e-04	4	134	2	PS51049
Domain	KASH	SYNE1 SYNE2	3.04e-04	4	134	2	SM01249
Domain	KASH	SYNE1 SYNE2	3.04e-04	4	134	2	PF10541
Domain	BRO1	PTPN23 RHPN1	5.04e-04	5	134	2	PF03097
Domain	BRO1_dom	PTPN23 RHPN1	5.04e-04	5	134	2	IPR004328
Domain	BRO1	PTPN23 RHPN1	5.04e-04	5	134	2	SM01041
Domain	BRO1	PTPN23 RHPN1	5.04e-04	5	134	2	PS51180
Domain	-	PTPN23 RHPN1	5.04e-04	5	134	2	1.25.40.280
Domain	DUF1041	CADPS2 UNC13A	5.04e-04	5	134	2	SM01145
Domain	-	LRRC45 FBXL4 NLRP14 NOD1 LRRIQ1 LGI3 TLR4 ZER1 LRRC41	5.21e-04	321	134	9	3.80.10.10
Domain	TPR_8	TTC21A PEX5L IFIT3 ANAPC7	5.65e-04	53	134	4	PF13181
Domain	Galactose-bd-like	EPHB2 ZZEF1 HERC2 EPHA3 EPHA4	5.81e-04	94	134	5	IPR008979
Domain	L_dom-like	LRRC45 FBXL4 NLRP14 NOD1 LRRIQ1 LGI3 TLR4 ZER1 LRRC41	6.08e-04	328	134	9	IPR032675
Domain	SAM_DOMAIN	EPHB2 STARD13 ANKS3 EPHA3 EPHA4	6.10e-04	95	134	5	PS50105
Domain	LRR_6	LRRC45 NLRP14 NOD1 TLR4	6.51e-04	55	134	4	PF13516
Domain	SAM	EPHB2 STARD13 ANKS3 EPHA3 EPHA4	6.70e-04	97	134	5	IPR001660
Domain	Ephrin_rec_like	EPHB2 EPHA3 EPHA4	7.40e-04	25	134	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB2 EPHA3 EPHA4	7.40e-04	25	134	3	IPR011641
Domain	Xpo1	XPO5 IPO13	7.52e-04	6	134	2	PF08389
Domain	Exportin-1/Importin-b-like	XPO5 IPO13	7.52e-04	6	134	2	IPR013598
Domain	Leu-rich_rpt	LRRC45 FBXL4 NLRP14 NOD1 LRRIQ1 LGI3 TLR4 LRRC41	7.65e-04	271	134	8	IPR001611
Domain	Munc13_1	CADPS2 UNC13A	1.05e-03	7	134	2	IPR014770
Domain	APC_su10/DOC_dom	ZZEF1 HERC2	1.05e-03	7	134	2	IPR004939
Domain	MHD1	CADPS2 UNC13A	1.05e-03	7	134	2	PS51258
Domain	DOC	ZZEF1 HERC2	1.05e-03	7	134	2	PS51284
Domain	ANAPC10	ZZEF1 HERC2	1.05e-03	7	134	2	PF03256
Domain	DUF1041	CADPS2 UNC13A	1.05e-03	7	134	2	PF06292
Domain	CAPS_dom	CADPS2 UNC13A	1.05e-03	7	134	2	IPR010439
Domain	APC10	ZZEF1 HERC2	1.05e-03	7	134	2	SM01337
Domain	TPR_REGION	TTC21A PTPN23 PEX5L IFIT3 ANAPC7 CFAP46	1.23e-03	165	134	6	PS50293
Domain	TPR	TTC21A PTPN23 PEX5L IFIT3 ANAPC7 CFAP46	1.23e-03	165	134	6	PS50005
Domain	Pkinase_Tyr	EPHB2 ANKK1 YES1 EPHA3 EPHA4	2.39e-03	129	134	5	PF07714
Domain	Ephrin_rec_like	EPHB2 EPHA3	2.69e-03	11	134	2	PF07699
Domain	Prot_kinase_dom	EPHB2 ANKK1 CDC42BPG YES1 RPS6KC1 CDK13 PAN3 STKLD1 EPHA3 EPHA4	2.79e-03	489	134	10	IPR000719
Domain	ARM	INSC ZER1 GCN1	2.94e-03	40	134	3	SM00185
Domain	PROTEIN_KINASE_DOM	EPHB2 ANKK1 CDC42BPG YES1 RPS6KC1 CDK13 PAN3 STKLD1 EPHA3 EPHA4	2.96e-03	493	134	10	PS50011
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHB2 ANKK1 YES1 EPHA3 EPHA4	3.19e-03	138	134	5	IPR001245
Domain	COS	TRIM54 TRIM9	3.22e-03	12	134	2	PS51262
Domain	Quinoprot_gluc/sorb_DH	LGI3 HHIPL1	3.22e-03	12	134	2	IPR011041
Domain	COS_domain	TRIM54 TRIM9	3.22e-03	12	134	2	IPR017903
Domain	SAM_2	STARD13 EPHA3 EPHA4	3.61e-03	43	134	3	PF07647
Domain	Tyr_kinase_cat_dom	EPHB2 YES1 EPHA3 EPHA4	3.71e-03	88	134	4	IPR020635
Domain	TyrKc	EPHB2 YES1 EPHA3 EPHA4	3.71e-03	88	134	4	SM00219
Domain	SAM	EPHB2 ANKS3 EPHA3 EPHA4	3.71e-03	88	134	4	SM00454
Domain	TPR-contain_dom	TTC21A PTPN23 PEX5L IFIT3 ANAPC7	4.55e-03	150	134	5	IPR013026
Domain	Armadillo	INSC ZER1 GCN1	4.65e-03	47	134	3	IPR000225
Domain	LRR_1	LRRC45 FBXL4 LRRIQ1 LGI3 TLR4 LRRC41	5.02e-03	219	134	6	PF00560
Domain	PROTEIN_KINASE_TYR	EPHB2 YES1 EPHA3 EPHA4	5.25e-03	97	134	4	PS00109
Domain	Tyr_kinase_AS	EPHB2 YES1 EPHA3 EPHA4	5.25e-03	97	134	4	IPR008266
Domain	Kinase-like_dom	EPHB2 ANKK1 CDC42BPG YES1 RPS6KC1 CDK13 PAN3 STKLD1 EPHA3 EPHA4	5.74e-03	542	134	10	IPR011009
Domain	IBN_N	XPO5 IPO13	5.74e-03	16	134	2	SM00913
Domain	PROTEIN_KINASE_ATP	EPHB2 ANKK1 CDC42BPG YES1 RPS6KC1 CDK13 STKLD1 EPHA3 EPHA4	5.90e-03	459	134	9	PS00107
Domain	Importin-beta_N	XPO5 IPO13	6.48e-03	17	134	2	IPR001494
Domain	-	EPHB2 ANKS3 EPHA3 EPHA4	7.16e-03	106	134	4	1.10.150.50
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STARD13 FAM184B ZSWIM5 SYNE1 FAM178B SANBR CCDC77 TRIP12 ARPC4 RPS6KC1 FASN PSIP1 CDK13 SYNE2 KRT40 NLE1 CADPS2 CCDC89 TASOR ANAPC7 NIPBL MED13 CFAP46 EPHA4 AGAP2	5.83e-10	1442	139	25	35575683
Pubmed	Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.	EPHB2 YES1 EPHA3 EPHA4	8.47e-09	7	139	4	9632142
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TBRG4 SANBR ZZEF1 TRIM9 SUPT6H NBEAL2 IPO13 SENP6 HHIPL1 AMOTL2 ESPL1 ANKS3 MED13	2.30e-07	529	139	13	14621295
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 BRIP1 NACC1 GEMIN5 TRIP12 FASN TBC1D4 PSIP1 CDK13 SENP6 ZNF579 ESPL1 SNRNP200 NIPBL MED13	5.40e-07	774	139	15	15302935
Pubmed	Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.	EPHB2 EPHA3 EPHA4	6.21e-07	5	139	3	8552593
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	TBRG4 GEMIN5 TRIP12 IFIT3 FASN TBC1D4 CDK13 ZNF579 ANKRD52 NIPBL ANKS3 PSRC1	9.31e-07	503	139	12	16964243
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TRIP12 TBC1D4 CADPS2 TASOR SNRNP200 UNC13A MED13	9.81e-07	130	139	7	12421765
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	ZZEF1 TRIP12 SUPT6H HERC2 TASOR ANKRD52 ANAPC7 LRRC41	2.37e-06	212	139	8	33853758
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NPEPPS GEMIN5 TRIP12 FASN XPO5 SUPT6H SYNE2 NLE1 HERC2 GCN1 ANKRD52 SNRNP200 NIPBL	2.40e-06	653	139	13	22586326
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SYNE1 TRIP12 RYR3 TRIM9 LGI3 NECAB3 SENP6 ANKRD24 ANKRD36 SMPD3 MORC3 HERC2 AMOTL2 CADPS2 SNRNP200 NIPBL MED13 AGAP2	3.96e-06	1285	139	18	35914814
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHB2 EPHA3 EPHA4	5.16e-06	9	139	3	11403717
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FAM184B GAS2L3 STXBP4 GEMIN5 PTPN23 GCNT2 CCDC77 TRIP12 ZRANB3 RPS6KC1 INTS14 TLR4 PAN3 CPLANE1 ESPL1 TASOR	7.45e-06	1084	139	16	11544199
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 NACC1 NPEPPS SYNE1 SH3BP1 PEX5L ARPC4 AKAP9 SYNE2 HERC2 PCDH8 NIPBL UNC13A EPHA4 AGAP2	7.76e-06	963	139	15	28671696
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDC42BPG NACC1 DISC1 TTC21A ZZEF1 TRIP12 RPS6KC1 TGFB1I1 TBC1D4 PSIP1 TRIM9 AMOTL2 SNRNP200	8.69e-06	736	139	13	29676528
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	EPHB2 EPHA3 EPHA4	1.01e-05	11	139	3	22171039
Pubmed	Ephrin/ephrin receptor expression during early stages of mouse inner ear development.	EPHB2 EPHA3 EPHA4	1.34e-05	12	139	3	21465626
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	ANKK1 TRIP12 FASN SUPT6H GCN1 SNRNP200 NIPBL MED13	1.47e-05	272	139	8	31010829
Pubmed	Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas.	NACC1 FASN	1.59e-05	2	139	2	22653145
Pubmed	The protective effect of cinnamaldehyde on lipopolysaccharide induced acute lung injury in mice.	NFKB1 TLR4	1.59e-05	2	139	2	28886315
Pubmed	Toll-like receptor 4 promotes high glucose-induced catabolic and inflammatory responses in chondrocytes in an NF-κB-dependent manner.	NFKB1 TLR4	1.59e-05	2	139	2	30953645
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.59e-05	2	139	2	11792814
Pubmed	Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability.	NFKB1 TLR4	1.59e-05	2	139	2	25757594
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.59e-05	2	139	2	24931616
Pubmed	[Investigation of inflammatory responses of alveolar epithelial cells induced by lipopolysaccharide and mechanism].	NFKB1 TLR4	1.59e-05	2	139	2	21729627
Pubmed	Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.	EPHB2 EPHA4	1.59e-05	2	139	2	11572780
Pubmed	Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases.	NFKB1 TLR4	1.59e-05	2	139	2	18945182
Pubmed	Overexpression of EphA4 gene and reduced expression of EphB2 gene correlates with liver metastasis in colorectal cancer.	EPHB2 EPHA4	1.59e-05	2	139	2	18695888
Pubmed	Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression.	NOD1 TLR4	1.59e-05	2	139	2	28536249
Pubmed	Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling.	EPHA3 EPHA4	1.59e-05	2	139	2	18403711
Pubmed	The TLR4/NF-κB signaling pathway mediates the growth of colon cancer.	NFKB1 TLR4	1.59e-05	2	139	2	25555874
Pubmed	Role of nucleotide-binding oligomerization domain 1 (NOD1) in pericyte-mediated vascular inflammation.	NOD1 TLR4	1.59e-05	2	139	2	26915562
Pubmed	Hypoxic preconditioning decreases nuclear factor κB activity via Disrupted in Schizophrenia-1.	DISC1 NFKB1	1.59e-05	2	139	2	26615762
Pubmed	Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages.	NFKB1 TLR4	1.59e-05	2	139	2	17082484
Pubmed	Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases.	NOD1 NFKB1	1.59e-05	2	139	2	37996457
Pubmed	Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling.	NOD1 TLR4	1.59e-05	2	139	2	24882704
Pubmed	HGF and direct mesenchymal stem cells contact synergize to inhibit hepatic stellate cells activation through TLR4/NF-kB pathway.	NFKB1 TLR4	1.59e-05	2	139	2	22927965
Pubmed	[The role of TLR4/NF-κB signaling pathway in sleep deprivation induced Meniere's disease].	NFKB1 TLR4	1.59e-05	2	139	2	37828881
Pubmed	Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway.	NFKB1 TLR4	1.59e-05	2	139	2	32128893
Pubmed	Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB.	NFKB1 TLR4	1.59e-05	2	139	2	24290604
Pubmed	Novel type I hair keratins K39 and K40 are the last to be expressed in differentiation of the hair: completion of the human hair keratin catalog.	KRT39 KRT40	1.59e-05	2	139	2	17301834
Pubmed	Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians.	FASN NFKB1	1.59e-05	2	139	2	25173531
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.59e-05	2	139	2	22768332
Pubmed	Platelet TLR4-ERK5 Axis Facilitates NET-Mediated Capturing of Circulating Tumor Cells and Distant Metastasis after Surgical Stress.	PADI4 TLR4	1.59e-05	2	139	2	33687949
Pubmed	Clinical Significance of Serum TLR4 and NF-κB Levels in Neonatal Jaundice.	NFKB1 TLR4	1.59e-05	2	139	2	33073966
Pubmed	Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain.	EPHB2 EPHA4	1.59e-05	2	139	2	18410519
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.59e-05	2	139	2	17267447
Pubmed	Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.	EPHB2 EPHA4	1.59e-05	2	139	2	19542617
Pubmed	TAK-242 attenuates acute cigarette smoke-induced pulmonary inflammation in mouse via the TLR4/NF-κB signaling pathway.	NFKB1 TLR4	1.59e-05	2	139	2	26944017
Pubmed	Polymorphisms in NFKB1 and TLR4 and interaction with dietary and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study.	NFKB1 TLR4	1.59e-05	2	139	2	25705893
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.59e-05	2	139	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.59e-05	2	139	2	24586179
Pubmed	[Expression and significance of toll like receptor 4 mRNA and nuclear factor-kappaB p50 mRNA in human normal nasal mucosa after stimulation by lipopolysaccharide].	NFKB1 TLR4	1.59e-05	2	139	2	17111814
Pubmed	The roles of Eph receptors in contextual fear conditioning memory formation.	EPHB2 EPHA4	1.59e-05	2	139	2	26165136
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.59e-05	2	139	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.59e-05	2	139	2	31578382
Pubmed	Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury.	NFKB1 TLR4	1.59e-05	2	139	2	22272328
Pubmed	A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.	NOD1 TLR4	1.59e-05	2	139	2	22870324
Pubmed	Toll-like receptor 4-mediated nuclear factor kappa B activation is essential for sensing exogenous oxidants to propagate and maintain oxidative/nitrosative cellular stress.	NFKB1 TLR4	1.59e-05	2	139	2	24058497
Pubmed	Alpinetin attenuates inflammatory responses by interfering toll-like receptor 4/nuclear factor kappa B signaling pathway in lipopolysaccharide-induced mastitis in mice.	NFKB1 TLR4	1.59e-05	2	139	2	23669335
Pubmed	[The effect of TLR4/NF-kappaB activation and LOX-1 on monocyte adhesion to endothelium].	NFKB1 TLR4	1.59e-05	2	139	2	16266460
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GAS2L3 NPEPPS SYNE1 YES1 TRIP12 FASN PSIP1 SUPT6H SYNE2 NLE1 HERC2 GCN1 ANAPC7 SNRNP200 NIPBL	1.60e-05	1024	139	15	24711643
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	GEMIN5 TRIP12 FASN XPO5 HERC2 GCN1 SNRNP200	1.79e-05	202	139	7	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	GEMIN5 PTPN23 RFWD3 FASN KIDINS220 GCN1 SNRNP200	1.79e-05	202	139	7	24639526
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	NACC1 RBL1 TRIM54 ASB13 TRIM9 ANAPC7	2.04e-05	138	139	6	28786561
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	BRIP1 TASOR ANAPC7 SNRNP200 NIPBL	2.27e-05	84	139	5	26299517
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	SYNE1 LRRIQ1 AKAP9 GAB4 CTNNA3 ESPL1	3.51e-05	152	139	6	34299191
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 PTPN23 XPO5 TRIM9 SYNE2 GCN1 SNRNP200	3.58e-05	225	139	7	12168954
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB2 EPHA3 EPHA4	4.08e-05	17	139	3	12217323
Pubmed	Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.	EPHB2 EPHA3 EPHA4	4.08e-05	17	139	3	12971893
Pubmed	Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.	STARD13 INPP1 AKAP9 NFKB1	4.50e-05	49	139	4	24652767
Pubmed	Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB.	IFIT3 NFKB1	4.75e-05	3	139	2	27602766
Pubmed	4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.	NFKB1 TLR4	4.75e-05	3	139	2	26745712
Pubmed	Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling.	NFKB1 TLR4	4.75e-05	3	139	2	15610077
Pubmed	Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades.	NFKB1 TLR4	4.75e-05	3	139	2	26386401
Pubmed	Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes.	NOD1 NFKB1	4.75e-05	3	139	2	24219284
Pubmed	Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages.	NFKB1 TLR4	4.75e-05	3	139	2	22627090
Pubmed	Prolonged exposure to high humidity and high temperature environment can aggravate influenza virus infection through intestinal flora and Nod/RIP2/NF-κB signaling pathway.	NOD1 NFKB1	4.75e-05	3	139	2	33091794
Pubmed	Identification of ocular regulatory functions of core histone variant H3.2.	EPHB2 EPHA3	4.75e-05	3	139	2	36529279
Pubmed	TLR4/NF-κB axis induces fludarabine resistance by suppressing TXNIP expression in acute myeloid leukemia cells.	NFKB1 TLR4	4.75e-05	3	139	2	30336978
Pubmed	The Effects and Mechanisms of Xanthones in Alzheimer's Disease: A Systematic Review.	NFKB1 TLR4	4.75e-05	3	139	2	37578655
Pubmed	Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-kappaB-mediated signalling, moderated by TGF-beta.	NFKB1 TLR4	4.75e-05	3	139	2	15661045
Pubmed	Combined stimulation of Toll-like receptor 5 and NOD1 strongly potentiates activity of NF-κB, resulting in enhanced innate immune reactions and resistance to Salmonella enterica serovar Typhimurium infection.	NOD1 NFKB1	4.75e-05	3	139	2	23897616
Pubmed	Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.	NOD1 NFKB1	4.75e-05	3	139	2	34825931
Pubmed	Synergistic effects of NOD1 or NOD2 and TLR4 activation on mouse sickness behavior in relation to immune and brain activity markers.	NOD1 TLR4	4.75e-05	3	139	2	25218901
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	4.75e-05	3	139	2	16079285
Pubmed	Silencing TLR4/MyD88/NF-κB Signaling Pathway Alleviated Inflammation of Corneal Epithelial Cells Infected by ISE.	NFKB1 TLR4	4.75e-05	3	139	2	33174138
Pubmed	Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway.	NFKB1 TLR4	4.75e-05	3	139	2	19492426
Pubmed	Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells.	NFKB1 TLR4	4.75e-05	3	139	2	19215923
Pubmed	Peroxiredoxin 1-mediated activation of TLR4/NF-κB pathway contributes to neuroinflammatory injury in intracerebral hemorrhage.	NFKB1 TLR4	4.75e-05	3	139	2	27821296
Pubmed	Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis.	NOD1 TLR4	4.75e-05	3	139	2	17309748
Pubmed	Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.	IL18R1 TLR4	4.75e-05	3	139	2	25327457
Pubmed	[HMGB1/TLR4/NF-κB signaling pathway and role of vitamin D in asthmatic mice].	NFKB1 TLR4	4.75e-05	3	139	2	28100331
Pubmed	The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.	NFKB1 TLR4	4.75e-05	3	139	2	17538633
Pubmed	Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity.	NFKB1 TLR4	4.75e-05	3	139	2	18624726
Pubmed	Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles.	NFKB1 TLR4	4.75e-05	3	139	2	17010424
Pubmed	The genomic and clinical landscape of fetal akinesia.	RYR3 GCN1	4.75e-05	3	139	2	31680123
Pubmed	Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.	NOD1 TLR4	4.75e-05	3	139	2	20649597
Pubmed	Activation of TLR4 induces inflammatory muscle injury via mTOR and NF-κB pathways in experimental autoimmune myositis mice.	NFKB1 TLR4	4.75e-05	3	139	2	35276460
Pubmed	Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis.	NOD1 TLR4	4.75e-05	3	139	2	26989200
Pubmed	NLRC5 deficiency promotes myocardial damage induced by high fat diet in mice through activating TLR4/NF-κB.	NFKB1 TLR4	4.75e-05	3	139	2	28499247
Cytoband	2q11.2	FAM178B ANKRD36B ANKRD36 SNRNP200	7.06e-05	72	139	4	2q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr2q11	FAM178B ANKRD36C ANKRD36B ANKRD36 SNRNP200	1.08e-04	153	139	5	chr2q11
GeneFamily	Ankyrin repeat domain containing	ANKK1 ANKRD29 ANKRD36C ANKRD36B ANKRD44 ASB13 KIDINS220 NFKB1 ANKRD24 ANKRD36 ANKRD52 ANKS3 AGAP2	3.23e-10	242	93	13	403
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB2 EPHA3 EPHA4	4.60e-05	14	93	3	1095
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.56e-04	4	93	2	1252
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC21A PEX5L IFIT3 ANAPC7 CFAP46	3.18e-04	115	93	5	769
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD44 ANKRD52	3.87e-04	6	93	2	699
GeneFamily	Sterile alpha motif domain containing	EPHB2 ANKS3 EPHA3 EPHA4	1.10e-03	88	93	4	760
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	ZZEF1 HERC2	3.80e-03	18	93	2	91
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CDC42BPG PLEKHG4 GAB4 CADPS2 AGAP2	4.23e-03	206	93	5	682
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 TTC21A SANBR RHPN1 LRRIQ1 AKAP9 CROCC2 SYNE2 CPLANE1 CFAP46	6.72e-10	197	139	10	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	NPEPPS ANKRD36C ANKRD44 NFKB1 SYNE2 ANKRD36 NIPBL MED13	1.41e-07	188	139	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SANBR ANKRD36C LRRIQ1 PSIP1 ANKRD36 CPLANE1 DEUP1 CFAP46	1.80e-07	194	139	8	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ANKRD36C ANKRD44 AKAP9 CDK13 SYNE2 ANKRD36 SNRNP200	2.02e-07	197	139	8	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYT9 PEX5L TRIM9 CTNNA3 SMPD3 UNC13A EPHA3 TPH1	2.10e-07	198	139	8	8f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYT9 PEX5L TRIM9 CTNNA3 SMPD3 UNC13A EPHA3 TPH1	2.10e-07	198	139	8	e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ANKRD36C ANKRD44 AKAP9 CDK13 SYNE2 ANKRD36 SNRNP200	2.18e-07	199	139	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANKRD36B LRRIQ1 HOGA1 SYNE2 ANKRD36 ANKS3 CFAP46	6.12e-07	156	139	7	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ANKRD36C ANKRD44 AKAP9 CDK13 SYNE2 ANKRD36	2.54e-06	193	139	7	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	BRIP1 GAS2L3 RBL1 CCDC77 ZRANB3 RFWD3 ESPL1	2.54e-06	193	139	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 TTC21A SANBR RHPN1 LRRIQ1 CROCC2 CFAP46	2.62e-06	194	139	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Tracheal-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 GAS2L3 PEX5L TRIM9 INSC GAB4 CTNNA3	2.81e-06	196	139	7	b6226163d9fc93ecfff2115bb74408303a000490
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	TRIP12 ANKRD36B LRRIQ1 AKAP9 SYNE2 ANKRD36 NIPBL	3.10e-06	199	139	7	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRIP12 IFIT3 ANKRD44 AKAP9 CDK13 SYNE2 NIPBL	3.21e-06	200	139	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RBL1 RHPN1 FASN TBC1D4 SYNE2 ANKRD36	7.74e-06	150	139	6	c922dbb4c9c12ccf08bd5f6168b20606c605d052
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 ANKRD36C AKAP9 NFKB1 SYNE2 ANKRD36	1.63e-05	171	139	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	ANKRD36C ANKRD36B ANKRD44 NFKB1 SYNE2 ANKRD36	2.25e-05	181	139	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRIP1 GAS2L3 RBL1 CCDC77 ESPL1 PSRC1	2.32e-05	182	139	6	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RBL1 TBC1D4 PSIP1 ERP27 SYNE2 ANKRD36	2.39e-05	183	139	6	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL18R1 NBPF1 FASN TBC1D4 PSIP1 SYNE2	2.47e-05	184	139	6	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 GAS2L3 TEDC2 RFWD3 ESPL1 PSRC1	2.87e-05	189	139	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 FAM178B PEX5L RHPN1 INSC ACKR1	2.87e-05	189	139	6	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PEX5L TRIM9 ESPL1 PCDH8 UNC13A TPH1	2.95e-05	190	139	6	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PEX5L TRIM9 ESPL1 PCDH8 UNC13A TPH1	2.95e-05	190	139	6	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 ANKRD36B ANKRD44 PPP3CC SYNE2 ANKRD36	2.95e-05	190	139	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36C LRRIQ1 CROCC2 ANKRD36 DEUP1 CFAP46	2.95e-05	190	139	6	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PEX5L TRIM9 ESPL1 PCDH8 UNC13A TPH1	2.95e-05	190	139	6	a9a705455019e28d655636de73b07540798f82e6
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36C LRRIQ1 CROCC2 ANKRD36 DEUP1 CFAP46	2.95e-05	190	139	6	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ANKRD36C ANKRD36B ANKRD44 NFKB1 SYNE2 ANKRD36	3.13e-05	192	139	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	COPD-Lymphoid\|COPD / Disease state, Lineage and Cell class	TRERF1 SYNE1 YES1 ANKRD44 ERP27 SYNE2	3.13e-05	192	139	6	064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC21A RHPN1 LRRIQ1 CROCC2 CPLANE1 CFAP46	3.42e-05	195	139	6	79dc031258579ea328181dda33710dd897f1064a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANKRD29 GCNT2 AKAP9 CATSPER4 SYNE2 CADPS2	3.62e-05	197	139	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	TBRG4 ANKRD36C AKAP9 PSIP1 ANKRD36 NOL8	3.62e-05	197	139	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	Tracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 GAS2L3 TRIM9 INSC GAB4 CTNNA3	3.62e-05	197	139	6	e239caae24f40564a24ad909754f5436f767ccdb
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells\|LPS_only / Treatment groups by lineage, cell group, cell type	FAM178B GCNT2 NIBAN3 TBC1D4 TRIM9 CCDC154	3.62e-05	197	139	6	59ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	SYNE1 IFIT3 ERP27 SUPT6H SYNE2 CCDC89	3.72e-05	198	139	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-gd_T\|ICU-SEP / Disease, condition lineage and cell class	SYNE1 ANKRD36C IL18R1 PSIP1 SYNE2 ANKRD24	3.72e-05	198	139	6	b40899f8f5f32420fb4574069dd7afd9e7e70d91
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	YES1 TRIP12 LRRIQ1 AKAP9 SYNE2 NIPBL	3.83e-05	199	139	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	SYNE1 ANKRD36C IFIT3 ANKRD36B PSIP1 SYNE2	3.83e-05	199	139	6	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 ANKRD36C AKAP9 SYNE2 ANKRD36	3.90e-05	121	139	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SYNE1 ANKRD36C AKAP9 SYNE2 ANKRD36	6.58e-05	135	139	5	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	AT1-AT2_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD29 FAM184B RIPOR3 HOGA1 ZER1	9.22e-05	145	139	5	cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	INPP1 NPEPPS SYNE1 IFIT3 TGFB1I1	1.12e-04	151	139	5	0cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	INPP1 NPEPPS SYNE1 IFIT3 TGFB1I1	1.12e-04	151	139	5	b545823113a3450c5f841f7de48bf0937593544f
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	CDC42BPG BRIP1 LRRC45 RBL1 SMPD3	1.22e-04	154	139	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 SYNE1 IL18R1 TBC1D4 TPH1	1.22e-04	154	139	5	f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 RBL1 SYNE1 SANBR GAB4	1.26e-04	155	139	5	5d157478669b609e1f0f0a75afd0112571fc2c46
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SYNE1 ANKRD36C ANKRD36B SYNE2 ANKRD36	1.30e-04	156	139	5	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B NIBAN3 RFWD3 ANKRD44 RUBCN	1.34e-04	157	139	5	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SANBR RHPN1 LRRIQ1 DEUP1 CFAP46	1.34e-04	157	139	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 GCNT2 TRIM9 CTNNA3 RUFY4	1.60e-04	163	139	5	abec4389cd88252449f110fe95416d67424b403a
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 NACC1 RYR3 ESPL1 PSRC1	1.64e-04	164	139	5	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 IL18R1 RYR3 ANKRD44 XKR3	1.64e-04	164	139	5	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRIP1 NACC1 RYR3 ESPL1 PSRC1	1.64e-04	164	139	5	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	facs-Kidney-nan-3m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR3 DFFB PPP3CC PAN3 EPHA3	1.69e-04	165	139	5	ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 CCDC77 ZRANB3 NECAB3 PSRC1	1.69e-04	165	139	5	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 PLEKHG4 ZRANB3 ESPL1 PSRC1	1.84e-04	168	139	5	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 PLEKHG4 ZRANB3 ESPL1 PSRC1	1.84e-04	168	139	5	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FAM184B NIBAN3 SMPD3 ESPL1 RUBCN	1.84e-04	168	139	5	c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 PLEKHG4 ZRANB3 ESPL1 PSRC1	1.84e-04	168	139	5	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC21A LRRIQ1 CROCC2 CPLANE1 CFAP46	1.89e-04	169	139	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	NIBAN3 HOGA1 SMPD3 STKLD1 RUBCN	1.94e-04	170	139	5	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	NIBAN3 NR5A1 SMPD3 RUBCN RUFY4	1.99e-04	171	139	5	1f8e66073088fc1969782e443bf00f8c1877ea91
ToppCell	mild-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TRERF1 SYNE1 YES1 SYNE2 SMPD3	1.99e-04	171	139	5	5c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell	facs-Marrow-KLS-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 SH3BP1 RHPN1 TBC1D4 OCSTAMP	2.05e-04	172	139	5	979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCell	facs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 SH3BP1 RHPN1 TBC1D4 OCSTAMP	2.05e-04	172	139	5	f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 SYNE1 IL18R1 TBC1D4 NBEAL2	2.05e-04	172	139	5	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 SYNE1 IL18R1 TBC1D4 NBEAL2	2.05e-04	172	139	5	953b05f776348cff784e79c93df65841939d880f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 IL18R1 SYNE2 ANKRD36 CCDC89	2.22e-04	175	139	5	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	PEX5L TRIM9 UNC13A EPHA3 TPH1	2.22e-04	175	139	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	PEX5L TRIM9 UNC13A EPHA3 TPH1	2.22e-04	175	139	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRERF1 SYNE1 IFIT3 NBEAL2 SYNE2	2.28e-04	176	139	5	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 IL18R1 SYNE2 ANKRD36 CCDC89	2.28e-04	176	139	5	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 IFIT3 SYNE2 CPLANE1 RUBCN	2.34e-04	177	139	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 IFIT3 SYNE2 CPLANE1 RUBCN	2.34e-04	177	139	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	PLEKHG4 TGFB1I1 CCM2L NLE1 EPHA4	2.34e-04	177	139	5	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SYNE1 IFIT3 SYNE2 CPLANE1 RUBCN	2.34e-04	177	139	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	PADI4 IL18R1 TGFB1I1 SMPD3 RUBCN	2.34e-04	177	139	5	43e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 IFIT3 SYNE2 CPLANE1 RUBCN	2.34e-04	177	139	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 IFIT3 SYNE2 CPLANE1 RUBCN	2.34e-04	177	139	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE1 IFIT3 AKAP9 SYNE2 TASOR	2.40e-04	178	139	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 PEX5L INTS14 INSC	2.53e-04	180	139	5	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	facs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 PLEKHG4 PEX5L INSC LGI3	2.53e-04	180	139	5	c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 PEX5L INTS14 INSC	2.53e-04	180	139	5	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 PEX5L INTS14 INSC	2.53e-04	180	139	5	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	facs-Marrow-B-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 PLEKHG4 PEX5L INSC LGI3	2.53e-04	180	139	5	07ac979b21be2425294d9818c48b5a1e6f014c19
ToppCell	severe-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TRERF1 SYNE1 YES1 SYNE2 SMPD3	2.53e-04	180	139	5	ac03812b1409435c55d323a7516deeac82bd3509
ToppCell	RV\|World / Chamber and Cluster_Paper	TRIM54 GCNT2 TBC1D4 AKAP9 CTNNA3	2.59e-04	181	139	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CCDC77 RFWD3 ESPL1 PSRC1	2.66e-04	182	139	5	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRIM54 LRRIQ1 CFAP46 EPHA3 EPHA4	2.66e-04	182	139	5	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRIP1 GAS2L3 RBL1 CCDC77 ESPL1	2.66e-04	182	139	5	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	IFIT3 TGFB1I1 TBC1D4 NBEAL2 ACKR1	2.73e-04	183	139	5	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	STARD13 GAS2L3 FIGNL2 CTNNA3 MED13	2.80e-04	184	139	5	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 GAS2L3 PEX5L ZRANB3 SMPD3	2.87e-04	185	139	5	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	BRIP1 ZSWIM5 RBL1 ZRANB3 MED13	2.94e-04	186	139	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BRIP1 ZSWIM5 RBL1 ZRANB3 MED13	2.94e-04	186	139	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZZEF1 SIDT2 TBC1D4 SENP6 GCN1	3.01e-04	187	139	5	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GAS2L3 PEX5L INSC SMPD3 ESPL1	3.01e-04	187	139	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	STARD13 RIPOR3 FASN TBC1D4 EPHA4	3.01e-04	187	139	5	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SYNE1 YES1 IL18R1 NFKB1 SYNE2	3.01e-04	187	139	5	6981b856187a2e689260ecb7d0a1193a374ee9b9
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	BRIP1 RBL1 RFWD3 TBC1D4 IPO13 SENP6 TASOR NIPBL MED13	2.47e-06	190	138	9	2619_DN
Disease	p-cresol sulfate measurement	STARD13 PSIP1 EPHA4	5.25e-05	16	137	3	EFO_0010998
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.28e-04	4	137	2	cv:CN293514
Disease	gonadal dysgenesis (implicated_via_orthology)	STARD13 NR5A1	1.28e-04	4	137	2	DOID:14447 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	TRERF1 ANKRD29 BRIP1 ZSWIM5 SYNE1 STXBP4 FASN NLRP14 AKAP9 SYNE2 NLE1 HERC2 PCDH8 NIPBL AGAP2	1.46e-04	1074	137	15	C0006142
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	2.12e-04	5	137	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	2.12e-04	5	137	2	C0410190
Disease	energy intake measurement	FIGNL2 ANKRD52	2.12e-04	5	137	2	EFO_0009374
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	3.17e-04	6	137	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	3.17e-04	6	137	2	C0410189
Disease	C-C motif chemokine 7 measurement	ANKRD44 ANKRD36 ACKR1	3.27e-04	29	137	3	EFO_0008054
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	4.43e-04	7	137	2	C0751337
Disease	Hyperoxaluria	HOGA1 NFKB1	5.88e-04	8	137	2	C0020500
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.37e-03	12	137	2	DOID:11726 (implicated_via_orthology)
Disease	Alzheimer disease, dementia	CFAP46 OCSTAMP	1.37e-03	12	137	2	MONDO_0001627, MONDO_0004975
Disease	hepatocellular carcinoma (is_implicated_in)	RYR3 XPO5 CDK13 NFKB1 TLR4	1.60e-03	181	137	5	DOID:684 (is_implicated_in)
Disease	CD209 antigen measurement	STKLD1 PSRC1	1.88e-03	14	137	2	EFO_0008077
Disease	Drug habituation	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0013170
Disease	Drug abuse	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0013146
Disease	Prescription Drug Abuse	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C4316881
Disease	Substance-Related Disorders	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0236969
Disease	Drug Use Disorders	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0013222
Disease	Drug Dependence	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C1510472
Disease	Substance Dependence	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0038580
Disease	Substance Use Disorders	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FAM184B SYNE1 CTNNA3 CADPS2	2.06e-03	115	137	4	C0029231
Disease	Substance abuse problem	FAM184B SYNE1 CTNNA3 CADPS2	2.13e-03	116	137	4	C0740858
Disease	ovarian neoplasm	BRIP1 FASN TLR4 NR5A1	3.58e-03	134	137	4	C0919267
Disease	Malignant neoplasm of ovary	BRIP1 FASN TLR4 NR5A1	3.88e-03	137	137	4	C1140680
Disease	Infiltrating duct carcinoma of female breast	ANKK1 RPS6KC1	4.24e-03	21	137	2	C3165106

Protein segments in the cluster

Peptide	Gene	Start	Entry
QDLLNADCLQRAAEK	UNC13A	596	Q9UPW8
VERLQQALGQLQAAC	AMOTL2	486	Q9Y2J4
DRLEQELLCASNRLQ	AKAP9	1946	Q99996
ELLCASNRLQELEAE	AKAP9	1951	Q99996
DAVGLLNCLEQRIQE	AKAP9	3056	Q99996
LLRLNDAALRALQEC	ELL3	26	Q9HB65
EALERCQILELLNAE	CCDC89	86	Q8N998
LQRLQAANDSVCRLQ	BLOC1S5	106	Q8TDH9
NFCLVLEAIQENLRQ	CATSPER4	376	Q7RTX7
IAAQDQQPDLCALLL	ANKK1	401	Q8NFD2
RCVQLLLAAGAQVDA	ASB13	66	Q8WXK3
SCAIQNQLARILAEF	SH3BP1	101	Q9Y3L3
CVRELVLQGADINLQ	ANKRD29	61	Q8N6D5
ATVNARANQDLALLC	CCDC77	441	Q9BR77
CAEAQCLLLLAQLAN	CFAP46	1636	Q8IYW2
CLAQQALDLLLNLAE	ACKR1	276	Q16570
ARQAGSQLCADILLQ	AGAP2	1131	Q99490
VQLRQEACATLLLQN	ANKRD36	106	A6QL64
LRQEACATLLLQNGA	ANKRD36B	96	Q8N2N9
LLCDEQAPQRQRLLA	DFFB	106	O76075
LCRLLLQQGAAANDQ	ANKRD24	196	Q8TF21
ALCLELLVNNGADVN	ANKRD52	286	Q8NB46
RLDLRDQELANAQTC	DEUP1	46	Q05D60
CNLVILAVANRDAAE	CCM2L	301	Q9NUG4
LLEQCQGLDAAVAQL	CCDC154	306	A6NI56
EACRLLIQSLQLQEA	DISC1	696	Q9NRI5
ANQELAQLELISRIC	CDK13	916	Q14004
NLVLIDQLSNCRLVD	CCDC83	246	Q8IWF9
QAELESAQCRLQLQV	RFWD3	371	Q6PCD5
LEQNLAAQDRVLCAL	PTPN23	616	Q9H3S7
ASAQDLIRQLLCRQE	CDC42BPG	306	Q6DT37
LTTALNCDQAAQRLE	NIBAN3	491	Q86XR2
LLNEQLDREALCDLT	PCDHB18P	31	Q96TA0
GIALLRNALANQSDC	ANAPC7	461	Q9UJX3
VQLRQEACATLLLQN	ANKRD36C	106	Q5JPF3
QGAILLVNCDRDNLE	PADI4	146	Q9UM07
ACRQQEALFQLLIEE	INPP1	21	P49441
KNVRLNCSALLNEED	IL18R1	231	Q13478
NINGRVLAQCNIDEL	KIDINS220	1241	Q9ULH0
IDNLENQLAEIRCDL	KRT40	351	Q6A162
ALANVLGAQVCQLER	HOGA1	241	Q86XE5
CLQLCLEEVANGLRN	HHIPL1	181	Q96JK4
SLIDNLEAQLAEIRC	KRT39	356	Q6A163
VCRDLNPNNILLNDR	RPS6KC1	926	Q96S38
AFAGQVDLDLLRCQQ	HERC2	2306	O95714
RLQADLNCLEDLVAS	GCNT2	166	Q8N0V5
LRFQLELEFVQCLAN	MED31	16	Q9Y3C7
QAQLQARLAALEAEL	FAM184B	876	Q9ULE4
DLAARNILVNSNLVC	EPHA4	746	P54764
DLAARNILVNSNLVC	EPHB2	746	P29323
AQACILNTTLDLLDR	ISOC2	111	Q96AB3
DAGCQLQELRNQLLL	MORC3	691	Q14149
GAQCADLVLLQELDR	PCDH8	191	O95206
EQAAIVALQRCLELQ	PEX5L	376	Q8IYB4
LFNARIAEEVNCLLA	NIPBL	41	Q6KC79
NCLLACRDDNLVSQL	NIPBL	51	Q6KC79
QDRLLSQLEANPNLC	NOD1	371	Q9Y239
LLAQARDEAQGACLQ	LRRC45	511	Q96CN5
DEAVLALRNLARQCS	GCN1	316	Q92616
ALCLELLVNNGADVN	ANKRD44	286	Q8N8A2
ANRLAAQLEQCALQD	PSRC1	81	Q6PGN9
CLRVNLTLADLEQLA	NOL8	481	Q76FK4
QEDSAIRCGQLDLLQ	SMPD3	466	Q9NY59
EQLAEGCRLAQQLFQ	NBPF1	146	Q3BBV0
QEQLAEGCRLAQQLF	NBPF1	416	Q3BBV0
LCQSQIREFNLLIEN	LRRIQ1	1166	Q96JM4
NRLANNSDCILAKDL	BRIP1	1156	Q9BX63
ALACNSLAGIQRENL	PAN3	696	Q58A45
NDGILLCQEALNAER	MALRD1	231	Q5VYJ5
ECNAIRQALQDLLSE	CTNNA3	331	Q9UI47
NCSALDAIREALQLL	ESPL1	646	Q14674
RNDIDLCQSDLQQVL	ESPL1	1041	Q14674
LNDAQGLCDQLAREI	CPLANE1	886	Q9H799
QNLVAQEDARCLELA	CROCC2	346	H7BZ55
IDELACNCTRLQQLD	FBXL4	551	Q9UKA2
DNGVLLCQLIDVLQN	GAS2L3	76	Q86XJ1
LRTINLNLCEQLDVD	GAB4	91	Q2WGN9
TDSLECLERLIDLNN	INTS14	166	Q96SY0
NNEAALECLRQAEEL	IFIT3	66	O14879
QLLNNFLRNDTLLCN	CADPS2	906	Q86UW7
DLAARNILINSNLVC	EPHA3	746	P29320
DAALVLDQLRACQAE	ANKS3	566	Q6ZW76
ICLFRLVDNEQLNLE	ERP27	106	Q96DN0
LQLNAIRVLLEACSD	INSC	411	Q1MX18
ILQRALAQQGCALSE	FIGNL2	566	A6NMB9
CRLQLNGNLQLELAQ	FASN	1186	P49327
CLEAVEQNNPRLLAQ	RUBCN	171	Q92622
LQDCEALIQAAFAAL	IPO13	236	O94829
ERTIQQCCENILLNA	NPEPPS	881	P55786
LCVLQQAREAELQAV	TBRG4	416	Q969Z0
QALQLLAELCARGAL	SYT9	11	Q86SS6
PDRLQLVCNALLAQE	NLE1	41	Q9NVX2
ENREVLQTLLCFLND	STARD13	781	Q9Y3M8
LQLLALQLDRQEFVC	NR5A1	356	Q13285
NHNRALLRNDLCALE	SIDT2	526	Q8NBJ9
DLRNLCTEAALLALQ	SPATA5L1	691	Q9BVQ7
ILLACNNLIDLDADE	TBC1D21	296	Q8IYX1
LCRQSNNLCLQREED	SYNE1	4221	Q8NF91
CQARAKELEDSLQQL	SYNE2	1931	Q8WXH0
NLLLECFDNLQVCLE	SYNE2	4601	Q8WXH0
GALDACAQRQLQLEQ	TEDC2	16	Q7L2K0
LADCQSEVLFLLQNL	LRRC41	656	Q15345
RLEALLQNCQAACAL	PLEKHG4	336	Q58EX7
AAGEALQALCQELNL	RBL1	16	P28749
LLQECLNLNSLDLDE	FAM178B	221	Q8IXR5
LALEARCQEQLLALL	NBEAL2	506	Q6ZNJ1
EALQLCLLNSELTRE	RUFY4	116	Q6ZNE9
AAQLRLSQEELLSCL	OCSTAMP	286	Q9BR26
DDLILLLQDQCTNLF	MED13	1186	Q9UHV7
NCINANLLTRIADLF	SANBR	266	Q6NSI8
RNLFCLQLDEVNVGA	STXBP4	261	Q6ZWJ1
QDCLAQLRLAQEAAQ	RHPN1	301	Q8TCX5
APELDCLIRLQAQNI	TASOR	1416	Q9UK61
AVRATLQAALCLENF	ARPC4	11	P59998
NRCIEALDELASLQV	PSIP1	371	O75475
ANINLADLTRAVNAL	SUPT6H	1541	Q7KZ85
VCEFLQNNNLLSIIR	PPP3CC	261	P48454
QLLNQRFESLCAVLE	TRIM54	211	Q9BYV2
CDINREQLNDIFHLL	TPH1	66	P17752
CRNEEQLLSQLQELQ	ZSWIM5	686	Q9P217
NLLFDIARIERCNQL	ZER1	376	Q7Z7L7
ENDARLQQAACLALK	RIPOR3	866	Q96MK2
QSIRLCQDRALLVNN	STKLD1	551	Q8NE28
AVRANQNLICDNLLP	RYR3	611	Q15413
SLALRCAQELLLANN	GEMIN5	1086	Q8TEQ6
LLLNEQELQLGAAEC	XPO5	256	Q9HAV4
QELQLGAAECLLIAV	XPO5	261	Q9HAV4
LEDLQRNCRQAITLN	SENP6	231	Q9GZR1
ELENAQSILQRCLEL	TTC21A	516	Q8NDW8
ADALVNCDLLLRDLN	TBC1D4	1271	O60343
LVAQCDALIDALNRR	TRIM9	316	Q9C026
ASDDRECENQLVLLL	SNRNP200	296	O75643
AIRCNILAIQISNDD	XKR3	211	Q5GH77
RCAAQALQNIAAISL	ZZEF1	2931	O43149
AALLENECQILQQRV	SPZ1	321	Q9BXG8
CELDRLLQELNATQF	TGFB1I1	91	O43294
ALNVLQRLCAATEQL	TRIP12	1116	Q14669
QRLCAATEQLNLQVD	TRIP12	1121	Q14669
RNLTFLDLSQCQLEQ	TLR4	496	O00206
ELERAAALQALQAQA	ZNF579	466	Q8NAF0
QLCNVNAQELFLRLR	ZRANB3	966	Q5FWF4
DLRAANILVGENLVC	YES1	396	P07947
DLQQRVENLLNLCCS	TRERF1	821	Q96PN7
ILNDLDLRGNSLNCD	LGI3	161	Q8N145
NNLLDDGVQLLCEAL	NLRP14	796	Q86W24
CLDLASVILNNPNLR	NLRP14	946	Q86W24
NFGNSILECLNEQRL	NACC1	11	Q96RE7
CLLLLVAAGADVNAQ	NFKB1	666	P19838
LQVNRLQELIDQLEC	NECAB3	226	Q96P71