Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	neural precursor cell proliferation	NES ATF5 ZNF423 ANKRD11 CNTNAP4 LRP2 SMARCD3 DMRTA2 ARHGEF2	7.89e-06	233	118	9	GO:0061351
GeneOntologyBiologicalProcess	membrane raft assembly	COL6A1 LRCH4 PACSIN2	5.01e-05	13	118	3	GO:0001765
GeneOntologyBiologicalProcess	cellular component disassembly	NES COL6A1 SPTBN1 LAMC1 TSC2 NOXO1 TPX2 SMARCD3 SMN1 ARHGEF2 CTTN PBXIP1 RUBCN	5.31e-05	617	118	13	GO:0022411
GeneOntologyBiologicalProcess	formation of cytoplasmic translation initiation complex	EIF3A EIF3B EIF3J	7.90e-05	15	118	3	GO:0001732
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex	EIF3A EIF3B EIF3J	9.07e-05	16	117	3	GO:0005852
GeneOntologyCellularComponent	eukaryotic 48S preinitiation complex	EIF3A EIF3B EIF3J	1.31e-04	18	117	3	GO:0033290
GeneOntologyCellularComponent	cytoplasmic ribonucleoprotein granule	SYNE1 PABPC1L2A LARP4B PRRC2C ZAR1 SMN1 EIF3B DDX4	1.38e-04	269	117	8	GO:0036464
GeneOntologyCellularComponent	eukaryotic 43S preinitiation complex	EIF3A EIF3B EIF3J	1.55e-04	19	117	3	GO:0016282
GeneOntologyCellularComponent	translation preinitiation complex	EIF3A EIF3B EIF3J	1.82e-04	20	117	3	GO:0070993
GeneOntologyCellularComponent	ribonucleoprotein granule	SYNE1 PABPC1L2A LARP4B PRRC2C ZAR1 SMN1 EIF3B DDX4	2.14e-04	287	117	8	GO:0035770
GeneOntologyCellularComponent	basement membrane	COL6A1 MATN2 LAMC1 TINAG P3H1	6.21e-04	122	117	5	GO:0005604
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex, eIF3m	EIF3A EIF3B	1.09e-03	9	117	2	GO:0071541
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	1.65e-03	11	117	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.65e-03	11	117	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	1.65e-03	11	117	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.65e-03	11	117	2	GO:0106094
MousePheno	abnormal choroid plexus morphology	ZNF423 SDCCAG8 LRP2 DMRTA2 FOXJ1	1.52e-05	48	92	5	MP:0000820
MousePheno	abnormal tela choroidea morphology	ZNF423 SDCCAG8 LRP2 DMRTA2 FOXJ1	1.52e-05	48	92	5	MP:0013306
MousePheno	increased kidney tumor incidence	SPTBN1 TSC2 PKD1	3.20e-05	10	92	3	MP:0010294
Domain	KASH	SYNE1 SYNE2	2.36e-04	4	118	2	IPR012315
Domain	KASH	SYNE1 SYNE2	2.36e-04	4	118	2	PS51049
Domain	KASH	SYNE1 SYNE2	2.36e-04	4	118	2	SM01249
Domain	KASH	SYNE1 SYNE2	2.36e-04	4	118	2	PF10541
Domain	Spectrin	SYNE1 SPTBN1 SYNE2	3.97e-04	23	118	3	PF00435
Domain	ACTININ_2	SYNE1 SPTBN1 SYNE2	3.97e-04	23	118	3	PS00020
Domain	ACTININ_1	SYNE1 SPTBN1 SYNE2	3.97e-04	23	118	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN1 SYNE2	3.97e-04	23	118	3	IPR001589
Domain	CH	SYNE1 SPTBN1 SYNE2 LRCH4	7.62e-04	65	118	4	SM00033
Domain	Spectrin_repeat	SYNE1 SPTBN1 SYNE2	7.97e-04	29	118	3	IPR002017
Domain	PKD	SORCS1 PKD1	8.14e-04	7	118	2	PF00801
Domain	CH	SYNE1 SPTBN1 SYNE2 LRCH4	1.01e-03	70	118	4	PF00307
Domain	-	SYNE1 SPTBN1 SYNE2 LRCH4	1.06e-03	71	118	4	1.10.418.10
Domain	SPEC	SYNE1 SPTBN1 SYNE2	1.07e-03	32	118	3	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTBN1 SYNE2	1.07e-03	32	118	3	IPR018159
Domain	CH	SYNE1 SPTBN1 SYNE2 LRCH4	1.18e-03	73	118	4	PS50021
Domain	CH-domain	SYNE1 SPTBN1 SYNE2 LRCH4	1.30e-03	75	118	4	IPR001715
Domain	PKD/Chitinase_dom	SORCS1 PKD1	1.38e-03	9	118	2	IPR022409
Domain	PKD	SORCS1 PKD1	1.38e-03	9	118	2	SM00089
Domain	PKD	SORCS1 PKD1	2.10e-03	11	118	2	PS50093
Domain	PKD_dom	SORCS1 PKD1	2.10e-03	11	118	2	IPR000601
Domain	-	SORCS1 PKD1	2.10e-03	11	118	2	2.60.40.670
Domain	Lactamase_B	MBLAC2 MBLAC1	2.95e-03	13	118	2	PF00753
Domain	Lactamase_B	MBLAC2 MBLAC1	3.94e-03	15	118	2	SM00849
Domain	Post-SET_dom	KMT2B SETD2	4.48e-03	16	118	2	IPR003616
Domain	PostSET	KMT2B SETD2	4.48e-03	16	118	2	SM00508
Domain	POST_SET	KMT2B SETD2	4.48e-03	16	118	2	PS50868
Domain	VWA	VWA3A COL6A1 MATN2	5.34e-03	56	118	3	PF00092
Domain	CONNEXINS_1	GJA3 GJA5	6.31e-03	19	118	2	PS00407
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TRPM4 KMT2B SYNE1 TWNK ZHX2 CRNKL1 SETD2 LARP4B TFPT SLC4A1AP TPX2 LRCH4 ANKRD11 RBM6 SMN1 EIF3A EIF3B ZNF579 HERC2 ARHGEF2 EIF3J TAPBP PBXIP1	1.86e-09	1497	121	23	31527615
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B SPTBN1 TBC1D2 SMARCAD1 MFAP1 SETD2 TRAFD1 SLC4A1AP ZNF644 TPX2 RBM6 EIF3B ZNF579 ARHGEF2 CTTN ESPL1	1.27e-08	774	121	16	15302935
Pubmed	Human transcription factor protein interaction networks.	TET2 KMT2B SPTBN1 TWNK ZHX2 MFAP1 LARP4B TFPT PRRC2C ZNF644 SYNE2 TPX2 RBM6 LRP2 SMARCD3 SMN1 EIF3A EIF3B HERC2 CTTN PACSIN2	2.24e-08	1429	121	21	35140242
Pubmed	The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.	EIF3A EIF3B EIF3J	4.09e-07	5	121	3	14688252
Pubmed	Changes in ribosomal binding activity of eIF3 correlate with increased translation rates during activation of T lymphocytes.	EIF3A EIF3B EIF3J	4.09e-07	5	121	3	15946946
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 NES SPTBN1 LAMC1 TBC1D22B TSC2 GRIP1 PRRC2C STARD9 SYNE2 ANKRD11 ARHGEF2 EIF3J WNK4	1.91e-06	861	121	14	36931259
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD2 LARP4B TPX2 SNX18 RBM6 SMN1 HERC2 ARHGEF2 CTTN ESPL1	3.44e-06	440	121	10	34244565
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PMS1 SYNE1 SPTBN1 LAMC1 TWNK SMARCAD1 MFAP1 HSPA12A SLC4A1AP P3H1 ZNF644 SYNE2 ANKRD11 HERC2 ESPL1 PBXIP1 PACSIN2 MAST3	4.01e-06	1487	121	18	33957083
Pubmed	Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.	EIF3A EIF3B EIF3J	6.64e-06	11	121	3	9822659
Pubmed	Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.	EIF3A EIF3B EIF3J	8.83e-06	12	121	3	14519125
Pubmed	Human DDX3 functions in translation and interacts with the translation initiation factor eIF3.	EIF3A EIF3B EIF3J	8.83e-06	12	121	3	18628297
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 ZSWIM8 SYNE1 ZNF423 SPTBN1 TSC2 SMARCAD1 ARMCX4 CRNKL1 ZNF197 PKD1 LRP2 HERC2 CTTN PBXIP1 GPRASP2	1.03e-05	1285	121	16	35914814
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDC42BPG LIAS KMT2B TBC1D2 TSC2 CSMD2 NOXO1 P3H1 ALDH16A1 PKD1 LRP2 EIF3A	1.05e-05	736	121	12	29676528
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	LAMC1 TBC1D22B MFAP1 GTF2B LARP4B TRAFD1 P3H1 ALDH16A1 SYNE2 RBM6 EIF3A EIF3B TAPBP PBXIP1	1.14e-05	1007	121	14	34597346
Pubmed	eIF3: a versatile scaffold for translation initiation complexes.	EIF3A EIF3B EIF3J	1.15e-05	13	121	3	16920360
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.20e-05	2	121	2	11792814
Pubmed	Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer.	EIF3A EIF3B	1.20e-05	2	121	2	27924037
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.20e-05	2	121	2	24931616
Pubmed	Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit.	EIF3B EIF3J	1.20e-05	2	121	2	17190833
Pubmed	Acrofacial dysostosis in a patient with the TSC2-PKD1 contiguous gene syndrome.	TSC2 PKD1	1.20e-05	2	121	2	11836366
Pubmed	Analysis of PKD1 for genomic deletion by multiplex ligation-dependent probe assay: absence of hot spots.	TSC2 PKD1	1.20e-05	2	121	2	18060739
Pubmed	TSC2/PKD1 contiguous gene syndrome, with emphasis on a case with an atypical mild polycystic kidney phenotype and a novel genetic variant.	TSC2 PKD1	1.20e-05	2	121	2	31176519
Pubmed	Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase.	MYLK CTTN	1.20e-05	2	121	2	15056655
Pubmed	Diagnosis and genotype-phenotype correlation in patients with PKD1/TSC2 contiguous gene deletion syndrome.	TSC2 PKD1	1.20e-05	2	121	2	35142283
Pubmed	Polycystin 1 is required for the structural integrity of blood vessels.	TSC2 PKD1	1.20e-05	2	121	2	10677526
Pubmed	TET2 Negatively Regulates Nestin Expression in Human Melanoma.	TET2 NES	1.20e-05	2	121	2	27102770
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.20e-05	2	121	2	22768332
Pubmed	The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.	TSC2 PKD1	1.20e-05	2	121	2	8661056
Pubmed	Renal Neoplasia in Polycystic Kidney Disease: An Assessment of Tuberous Sclerosis Complex-associated Renal Neoplasia and PKD1/TSC2 Contiguous Gene Deletion Syndrome.	TSC2 PKD1	1.20e-05	2	121	2	34876325
Pubmed	Two novel gross deletions of TSC2 in Malaysian patients with tuberous sclerosis complex and TSC2/PKD1 contiguous deletion syndrome.	TSC2 PKD1	1.20e-05	2	121	2	24683199
Pubmed	Imaging features of tuberous sclerosis complex with autosomal-dominant polycystic kidney disease: a contiguous gene syndrome.	TSC2 PKD1	1.20e-05	2	121	2	25355409
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.20e-05	2	121	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.20e-05	2	121	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.20e-05	2	121	2	24586179
Pubmed	Novel interaction of cortactin with endothelial cell myosin light chain kinase.	MYLK CTTN	1.20e-05	2	121	2	12408982
Pubmed	A common cortactin gene variation confers differential susceptibility to severe asthma.	MYLK CTTN	1.20e-05	2	121	2	18521921
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.20e-05	2	121	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.20e-05	2	121	2	31578382
Pubmed	Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endothelium.	MYLK CTTN	1.20e-05	2	121	2	20053363
Pubmed	Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.	PKD1 PAPPA	1.20e-05	2	121	2	31990681
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	KBTBD7 MFAP1 CRNKL1 ZNF644 TPX2 RBM6 ARHGEF2	1.34e-05	222	121	7	37071664
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 KMT2B HSPA12A SYNE2 ARHGEF2	1.38e-05	87	121	5	12465718
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	NES SYNE1 SYNE2	1.45e-05	14	121	3	19874786
Pubmed	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.	EIF3A EIF3B EIF3J	1.45e-05	14	121	3	18599441
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	LAMC1 TRAFD1 PRRC2C LRP2 SMN1 EIF3A HERC2 ARHGEF2 PBXIP1	1.66e-05	418	121	9	35338135
Pubmed	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.	EIF3A EIF3B EIF3J	1.81e-05	15	121	3	17322308
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KMT2B MYLK CSMD2 PKD1 TPX2 LRP2 SMARCD3 FOXJ1	2.10e-05	329	121	8	17474147
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	COL6A1 ZNF423 SDCCAG8 LAMC1 TBC1D22B IFNLR1 AP1AR PKD1 SNX18 ZNF579 HERC2 ARHGEF2 EIF3J RUBCN PACSIN2	2.19e-05	1215	121	15	15146197
Pubmed	Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.	TET2 COL6A1 ZNF423 DDX4	2.21e-05	47	121	4	32892421
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	COL6A1 LAMC1 GRIP1	2.23e-05	16	121	3	16880404
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	TET2 SPTBN1 CRNKL1 LARP4B SLC4A1AP PRRC2C EIF3A EIF3B ARHGEF2 CTTN	2.41e-05	551	121	10	34728620
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ZSWIM8 ZNF423 ADGRB2 LAMC1 TSC2 GRIP1 SETD2 SMN1 EIF3A CTTN	2.77e-05	560	121	10	21653829
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	SYNE1 PABPC1L2A LARP4B PRRC2C RBM6 EIF3A CTTN	3.51e-05	258	121	7	37794589
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	3.59e-05	3	121	2	16079285
Pubmed	eIF3 controls cell size independently of S6K1-activity.	EIF3A EIF3B	3.59e-05	3	121	2	26172298
Pubmed	Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.	TET2 DDX4	3.59e-05	3	121	2	23352810
Pubmed	Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.	TET2 DDX4	3.59e-05	3	121	2	21816367
Pubmed	Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.	TSC2 PKD1	3.59e-05	3	121	2	19321600
Pubmed	The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selection.	EIF3B EIF3J	3.59e-05	3	121	2	20060839
Pubmed	Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.	TET2 KMT2B	3.59e-05	3	121	2	31844322
Pubmed	Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex.	PKD1 PACSIN2	3.59e-05	3	121	2	24385601
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	3.59e-05	3	121	2	10878022
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	3.59e-05	3	121	2	12408964
Pubmed	Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.	EIF3A EIF3B	3.59e-05	3	121	2	11169732
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	3.59e-05	3	121	2	17462627
Pubmed	Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion.	PKD1 CTTN	3.59e-05	3	121	2	26096820
Pubmed	Concurrent Reduced Expression of Contiguous PKD1, TSC2 and NTHL1 Leading to Kidney Diseases and Multiple Diverse Renal Cancers.	TSC2 PKD1	3.59e-05	3	121	2	36581342
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	3.59e-05	3	121	2	33472039
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	3.59e-05	3	121	2	25516977
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SYNE1 SETD2 SYNE2 PKD1 EIF3A EIF3B	5.13e-05	187	121	6	26460568
Pubmed	CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo.	EIF3A EIF3B EIF3J	5.22e-05	21	121	3	17403899
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	SPTBN1 F2 CRNKL1 TRAFD1 SLC4A1AP ANKRD11 CTTN TAPBP WNK4	6.35e-05	497	121	9	36774506
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	COL6A1 TYSND1 LARP4B FOXRED2 HYLS1 EIF3A EIF3B HERC2 EIF3J PBXIP1 GPRASP2	6.81e-05	754	121	11	33060197
Pubmed	Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs.	EIF3A EIF3B	7.17e-05	4	121	2	9573242
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	7.17e-05	4	121	2	16648470
Pubmed	eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.	EIF3A EIF3B	7.17e-05	4	121	2	27462815
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	7.17e-05	4	121	2	28716842
Pubmed	ZHX2 Interacts with Ephrin-B and regulates neural progenitor maintenance in the developing cerebral cortex.	NES ZHX2	7.17e-05	4	121	2	19515908
Pubmed	The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development.	NES CTTN	7.17e-05	4	121	2	11044403
Pubmed	Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.	TSC2 PKD1	7.17e-05	4	121	2	20169078
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	7.17e-05	4	121	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	7.17e-05	4	121	2	20108321
Pubmed	Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.	TSC2 PKD1	7.17e-05	4	121	2	19255143
Pubmed	The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.	TSC2 PKD1	7.17e-05	4	121	2	18845692
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	7.17e-05	4	121	2	19596800
Pubmed	Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation.	PKD1 CTTN	7.17e-05	4	121	2	27179075
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	COL6A1 LAMC1 TAPBP	8.93e-05	25	121	3	17170699
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 ZNF423 SMARCAD1 ZHX2 PRRC2C STARD9 ZNF644 RUBCN	9.35e-05	407	121	8	12693553
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	PRRC2C PPM1L HERC2	1.13e-04	27	121	3	34709416
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ZSWIM8 LAMC1 TSC2 MFAP1 HERC2 ARHGEF2 PBXIP1	1.18e-04	313	121	7	38270169
Pubmed	A critical function of the pial basement membrane in cortical histogenesis.	NES LAMC1	1.19e-04	5	121	2	12122064
Pubmed	Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.	MYLK CTTN	1.19e-04	5	121	2	22219181
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	1.19e-04	5	121	2	22632968
Pubmed	Further characterisation of the translational termination-reinitiation signal of the influenza B virus segment 7 RNA.	EIF3A EIF3B	1.19e-04	5	121	2	21347434
Pubmed	Megalin deficiency induces critical changes in mouse spinal cord development.	NES LRP2	1.19e-04	5	121	2	18388738
Pubmed	Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes.	GJA3 GJA5	1.19e-04	5	121	2	1964417
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	1.19e-04	5	121	2	18396275
Pubmed	Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.	NES TSC2	1.19e-04	5	121	2	10096549
Pubmed	Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues.	GRIP1 GTF2B	1.19e-04	5	121	2	12529369
Pubmed	Variable promoter usage and alternative splicing in five mouse connexin genes.	GJA3 GJA5	1.19e-04	5	121	2	15676282
Interaction	ZBTB44 interactions	NES SETD2 SNX18 RBM6 ARHGEF2 PACSIN2	2.52e-06	67	117	6	int:ZBTB44
GeneFamily	Eukaryotic translation initiation factor 3	EIF3A EIF3B EIF3J	1.75e-05	13	73	3	1121
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	9.60e-05	4	73	2	1252
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CDC42BPG SPTBN1 PLEKHG6 GAB3 ARHGEF2	1.47e-03	206	73	5	682
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	PRUNE2 SORCS1 TINAG PRRC2C SETBP1 SYNE2 ANKRD11 RBM6 LRP2	9.13e-07	221	121	9	M39222
Coexpression	CUI_TCF21_TARGETS_2_UP	TRPM4 COL6A1 MATN2 PABPC1L2A GRIP1 ALDH16A1 SYNE2 TPX2 GREB1 ESPL1 GPRASP2	6.02e-06	437	121	11	M1610
Coexpression	GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP	TBC1D2 TWNK KBTBD7 TIGD2 STARD9 GAB3 HYLS1	1.39e-05	169	121	7	M6851
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	LIAS SYNE1 SDCCAG8 HERC2 ARHGEF2 C6orf47 PBXIP1	2.41e-05	184	121	7	M9005
Coexpression	GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN	PRUNE2 SPTBN1 LAMC1 TEP1 TRAFD1 HERC2 PBXIP1	3.85e-05	198	121	7	M9882
Coexpression	CUI_TCF21_TARGETS_2_UP	TRPM4 COL6A1 MATN2 GRIP1 ALDH16A1 SYNE2 TPX2 GREB1 ESPL1 GPRASP2	5.12e-05	455	121	10	MM1189
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	ARMCX4 GRIP1 MFAP1 SETD2 SLC4A1AP SETBP1 SYNE2 PPM1L TPX2 PAPPA DMRTA2 EIF3A FAM149B1 ZNF579 CTTN TAPBP MYBL1	3.46e-06	831	118	17	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	NES COL6A1 SDCCAG8 ADGRB2 GRIP1 SLC4A1AP SETBP1 SYNE2 TPX2 ANKRD11 CNTNAP4 LRP2 PAPPA DMRTA2 EIF3A ZNF579 RUBCN GPRASP2	8.05e-06	983	118	18	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500	COL6A1 SPTBN1 TINAG PRRC2C STARD9 SYNE2 ANKRD11	5.60e-05	175	118	7	gudmap_developingGonad_e14.5_ epididymis_500_k4
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	TET2 NES COL6A1 AARD PPFIBP2 MATN2 KBTBD7 HSPA12A STARD9 P3H1 SYNE2 TPX2 CTTN MYBL1	9.36e-05	768	118	14	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	AARD PPFIBP2 STARD9 P3H1 SYNE2 CTTN MYBL1	9.70e-05	191	118	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 PPFIBP2 GRIP1 HSPA12A SYNE2 PAPPA ZNF579	5.00e-07	174	121	7	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 ATF5 PPFIBP2 GRIP1 SYNE2 LRP2 ZNF579	6.51e-07	181	121	7	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 ATF5 PPFIBP2 GRIP1 SYNE2 LRP2 ZNF579	6.51e-07	181	121	7	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 MATN2 LAMC1 ADAMTSL3 SORCS1 PAPPA GREB1	6.76e-07	182	121	7	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	ILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GTF2B PRRC2C SYNE2 RBM6 CTTN TAPBP RUBCN	8.40e-07	188	121	7	2156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AARD ARMCX4 GRIP1 AP1AR NOXO1 FKBPL GPRASP2	1.27e-06	200	121	7	61bae10c8b12196d9cee766897971b81cb897191
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 SETD2 PRRC2C ZNF644 SYNE2 ANKRD11 EIF3A	1.27e-06	200	121	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWA3A PRUNE2 SYNE1 ZNF423 ADGRB2 LRP2	4.70e-06	158	121	6	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWA3A PRUNE2 SYNE1 ZNF423 ADGRB2 LRP2	4.70e-06	158	121	6	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	T_cells-GNLY+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SYNE1 PLEKHG6 SETBP1 PPM1L GAB3 MYBL1	7.39e-06	171	121	6	04c811817cfec45af5f2891793106cc7ddb0300e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 PPFIBP2 GRIP1 HSPA12A SYNE2 PAPPA	7.90e-06	173	121	6	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 MYLK GRIP1 HSPA12A SYNE2 LRP2	9.29e-06	178	121	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GRIP1 TINAG SYNE2 LRP2 PAPPA	9.90e-06	180	121	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 GRIP1 TINAG SYNE2 LRP2 PAPPA	1.19e-05	186	121	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	VWA3A COL6A1 MATN2 STARD9 SETBP1 GAB3	1.23e-05	187	121	6	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GRIP1 TINAG SYNE2 LRP2 PAPPA	1.23e-05	187	121	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 ATF5 MATN2 LAMC1 ADAMTSL3 SNX18	1.43e-05	192	121	6	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AARD ADAMTSL3 GRIP1 BMP6 FOXRED2 CNTNAP4	1.43e-05	192	121	6	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AARD ADAMTSL3 GRIP1 BMP6 FOXRED2 CNTNAP4	1.43e-05	192	121	6	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 ZNF423 MATN2 ADAMTSL3 SETBP1 PAPPA	1.43e-05	192	121	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL6A1 ZNF423 MATN2 ADAMTSL3 SETBP1 PAPPA	1.43e-05	192	121	6	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 ATF5 MATN2 LAMC1 ADAMTSL3 SNX18	1.43e-05	192	121	6	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SORCS1 SETBP1 SYNE2 ANKRD11 RBM6 LRP2	1.43e-05	192	121	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 ATF5 MATN2 LAMC1 ADAMTSL3 PAPPA	1.47e-05	193	121	6	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 ATF5 MATN2 LAMC1 ADAMTSL3 PAPPA	1.47e-05	193	121	6	22c58032e58730715224d7934968ce92d150b0e8
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 MYLK LAMC1 ADAMTSL3 SETBP1 EFCC1	1.47e-05	193	121	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 ZNF423 MATN2 ADAMTSL3 SETBP1 PAPPA	1.47e-05	193	121	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 ATF5 MATN2 LAMC1 ADAMTSL3 PAPPA	1.47e-05	193	121	6	573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	VWA3A SYNE1 SPTBN1 SYNE2 CTTN FOXJ1	1.61e-05	196	121	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	mLN-T_cell-gd_T\|T_cell / Region, Cell class and subclass	TET2 NAALADL1 MATN2 SETBP1 TPX2 FKBPL	1.61e-05	196	121	6	8f476408cd5a4ea9d25c763c66565343d7989b38
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	VWA3A SYNE1 SPTBN1 SYNE2 CTTN FOXJ1	1.61e-05	196	121	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 SLC9A4 PRRC2C SYNE2 ANKRD11 MYBL1	1.65e-05	197	121	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NES MATN2 SORCS1 SAA1 HSPA12A PAPPA	1.65e-05	197	121	6	b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	COL6A1 MYLK LAMC1 CSMD2 SETBP1 PAPPA	1.65e-05	197	121	6	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	COL6A1 MYLK LAMC1 ADAMTSL3 SETBP1 GREB1	1.70e-05	198	121	6	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 PRRC2C ZNF644 SYNE2 ANKRD11 MYBL1	1.75e-05	199	121	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 ZNF423 ADAMTSL3 SETBP1 PAPPA GREB1	1.80e-05	200	121	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	NES MYLK ADAMTSL3 STARD9 SYNE2 PPM1L	1.80e-05	200	121	6	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A1 MYLK MATN2 ADAMTSL3 SORCS1 GAB3	1.80e-05	200	121	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NES MYLK ADAMTSL3 STARD9 SYNE2 PPM1L	1.80e-05	200	121	6	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PRUNE2 COL6A1 MYLK SYNE1 MATN2 ADAMTSL3	1.80e-05	200	121	6	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	NES MYLK PPFIBP2 SYNE1 ADAMTSL3 HSPA12A	1.80e-05	200	121	6	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NES MYLK ADAMTSL3 STARD9 SYNE2 PPM1L	1.80e-05	200	121	6	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 MATN2 ADAMTSL3 SETBP1 PAPPA GREB1	1.80e-05	200	121	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A1 MYLK SYNE1 LAMC1 GJA5 EFCC1	1.80e-05	200	121	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG6 PPM1L SNX18 ZNF579 MAST3	6.55e-05	155	121	5	d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL6A1 TWNK SETBP1 C6orf47 FOXJ1	6.76e-05	156	121	5	a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A SORCS1 GRIP1 CNTNAP4 LRP2	7.62e-05	160	121	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A SORCS1 GRIP1 CNTNAP4 LRP2	7.62e-05	160	121	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1orf185 TPX2 ESPL1 DDX4 MYBL1	8.31e-05	163	121	5	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM83E TWNK F2 TPX2 GREB1	8.81e-05	165	121	5	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM83E TWNK F2 TPX2 GREB1	8.81e-05	165	121	5	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	MBLAC2 TYSND1 STARD9 SYNE2 PBXIP1	9.06e-05	166	121	5	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 PPFIBP2 GRIP1 HSPA12A SYNE2	9.32e-05	167	121	5	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 PPFIBP2 GRIP1 HSPA12A SYNE2	9.32e-05	167	121	5	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MATN2 PABPC1L2A SORCS1 HSPA12A PAPPA	9.59e-05	168	121	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES PPFIBP2 ADAMTSL3 HSPA12A PAPPA	1.01e-04	170	121	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MATN2 SDCCAG8 GJA5 HYLS1 ZNF579	1.04e-04	171	121	5	6a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MATN2 SDCCAG8 GJA5 HYLS1 ZNF579	1.04e-04	171	121	5	9be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	NES ATF5 ADAMTSL3 MBLAC1 SETBP1	1.10e-04	173	121	5	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 MATN2 SYNE2 PBXIP1 MYBL1	1.16e-04	175	121	5	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	ASK452-Epithelial-Secretory\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	TBC1D22B SORCS1 SAA1 EFCC1 WNK4	1.19e-04	176	121	5	dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MATN2 BMP6 HSPA12A TINAG MAST3	1.19e-04	176	121	5	792f414f5092aba14260b8e16378e793a822498e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 ADAMTSL3 SORCS1 CNTNAP4 PAPPA	1.22e-04	177	121	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TINAG SYNE2 LRP2 GREB1	1.22e-04	177	121	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES SYNE1 PRRC2C SYNE2 ANKRD11	1.26e-04	178	121	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SORCS1 TINAG LRP2 PAPPA	1.26e-04	178	121	5	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F2 MBLAC1 TPX2 EFCC1 FOXJ1	1.26e-04	178	121	5	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F2 MBLAC1 TPX2 EFCC1 FOXJ1	1.26e-04	178	121	5	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM83E TINAG PLEKHG6 LRP2 WNK4	1.29e-04	179	121	5	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM83E TINAG PLEKHG6 LRP2 WNK4	1.29e-04	179	121	5	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SORCS1 TINAG SYNE2 LRP2	1.32e-04	180	121	5	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MATN2 HYLS1 PAPPA GREB1 GPRASP2	1.32e-04	180	121	5	1e819c5c87704ec6535dfeaae56561895e239d07
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GRIP1 TINAG LRP2 PAPPA	1.32e-04	180	121	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	facs\|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B TNFSF13 SPTBN1 FAM83E NOXO1	1.39e-04	182	121	5	08f775135b451be709f5fc8e1cbcf63425794a2e
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GRIP1 TINAG SYNE2 LRP2	1.43e-04	183	121	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COL6A1 ATF5 AARD MATN2	1.43e-04	183	121	5	ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PPFIBP2 HSPA12A LRP2 PAPPA TAPBP	1.43e-04	183	121	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 GRIP1 TINAG SYNE2 LRP2	1.47e-04	184	121	5	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 SETD2 PRRC2C ANKRD11 EIF3A	1.47e-04	184	121	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	SYNE1 SYNE2 GAB3 RUBCN MYBL1	1.47e-04	184	121	5	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK PPFIBP2 ADAMTSL3 HSPA12A STARD9	1.47e-04	184	121	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF5 MYLK LAMC1 SYNE2 RUBCN	1.51e-04	185	121	5	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL6A1 MATN2 ADAMTSL3 SETBP1 GREB1	1.51e-04	185	121	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A1 ADAMTSL3 SETBP1 PAPPA GREB1	1.51e-04	185	121	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 TINAG SYNE2 LRP2 PAPPA	1.51e-04	185	121	5	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF5 MYLK LAMC1 SYNE2 RUBCN	1.51e-04	185	121	5	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 ZNF423 P3H1 PAPPA GREB1	1.54e-04	186	121	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 ARMCX4 GJA5 SETBP1 WNK4	1.54e-04	186	121	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 ZNF423 P3H1 PAPPA GREB1	1.54e-04	186	121	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell\|TCGA-Uvea / Sample_Type by Project: Shred V9	TEP1 GJA5 PLEKHG6 SETBP1 GREB1	1.54e-04	186	121	5	e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	COL6A1 MATN2 SORCS1 HSPA12A PAPPA	1.58e-04	187	121	5	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SORCS1 TINAG SYNE2 LRP2	1.58e-04	187	121	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL6A1 MYLK LAMC1 SETBP1 PAPPA	1.58e-04	187	121	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SORCS1 TINAG SYNE2 LRP2	1.58e-04	187	121	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 TINAG SYNE2 LRP2 PAPPA	1.58e-04	187	121	5	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 SYNE2 GAB3 PBXIP1 MYBL1	1.62e-04	188	121	5	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AARD GRIP1 BMP6 FOXRED2 CNTNAP4	1.62e-04	188	121	5	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	15-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	ADAMTSL3 GJA3 HSPA12A STARD9 PAPPA	1.62e-04	188	121	5	4963382e54aac06bf5047c7d725393db70667ee7
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	COL6A1 ADAMTSL3 SETBP1 PAPPA GREB1	1.62e-04	188	121	5	706a26c372add839d947749f0521a0e1f5c9b0ec
Disease	Polycystic kidneys, severe infantile with tuberous sclerosis	TSC2 PKD1	1.64e-05	2	120	2	C1838327
Disease	Prostatic Neoplasms	PMS1 TET2 TRPM4 PPFIBP2 TBC1D2 LAMC1 SMARCAD1 SETD2 LRP2 EIF3A GREB1	4.47e-05	616	120	11	C0033578
Disease	Malignant neoplasm of prostate	PMS1 TET2 TRPM4 PPFIBP2 TBC1D2 LAMC1 SMARCAD1 SETD2 LRP2 EIF3A GREB1	4.47e-05	616	120	11	C0376358
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	9.79e-05	4	120	2	cv:CN293514
Disease	Colorectal Carcinoma	TET2 TNFSF13 SYNE1 LAMC1 ADAMTSL3 BMP6 GTF2B SETBP1 TPX2 ETAA1 LRP2	1.42e-04	702	120	11	C0009402
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.63e-04	5	120	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	1.63e-04	5	120	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.43e-04	6	120	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	2.43e-04	6	120	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.40e-04	7	120	2	C0751337
Disease	cortical surface area measurement	TET2 ZNF423 SPTBN1 LAMC1 SMARCAD1 ADAMTSL3 GRIP1 BMP6 TIGD2 PRRC2C PKD1 FKBPL PAPPA DMRTA2 C6orf47	3.74e-04	1345	120	15	EFO_0010736
Disease	interleukin 18 receptor accessory protein measurement	SLC9A4 FKBPL	5.80e-04	9	120	2	EFO_0008179
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.05e-03	12	120	2	DOID:11726 (implicated_via_orthology)
Disease	Ciliopathies	ZNF423 SDCCAG8 TSC2 HYLS1	1.08e-03	110	120	4	C4277690
Disease	multiple myeloma	GRIP1 ANKRD11 SMARCD3 HERC2	1.15e-03	112	120	4	EFO_0001378
Disease	intraocular pressure measurement	COL6A1 SPTBN1 ADGRB2 F2 KBTBD7 GTF2B FKBPL HERC2	1.16e-03	509	120	8	EFO_0004695
Disease	cerebellar volume measurement	C1orf185 PAPPA DMRTA2	1.25e-03	52	120	3	EFO_0020864
Disease	Metabolic Bone Disorder	ANKRD11 LRP2	1.45e-03	14	120	2	C0005944
Disease	Nephrosis	NES F2	1.66e-03	15	120	2	C0027720
Disease	Osteopenia	ANKRD11 LRP2	1.66e-03	15	120	2	C0029453
Disease	acne	CDC42BPG NAALADL1 LAMC1 TBC1D22B	1.73e-03	125	120	4	EFO_0003894
Disease	cutaneous melanoma, hair color	PPFIBP2 SYNE2 HERC2	2.08e-03	62	120	3	EFO_0000389, EFO_0003924
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	KMT2B SETD2	2.14e-03	17	120	2	DOID:0060307 (is_implicated_in)
Disease	skin sensitivity to sun	ANKRD11 HERC2	2.68e-03	19	120	2	EFO_0004795
Disease	hemorrhoid	TET2 LIAS PAPPA MYO15A	3.11e-03	147	120	4	EFO_0009552
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TET2 TSC2 SETD2 SYNE2	3.18e-03	148	120	4	C0279702
Disease	autism spectrum disorder (implicated_via_orthology)	LAMC1 TSC2 CNTNAP4 GPRASP2	3.50e-03	152	120	4	DOID:0060041 (implicated_via_orthology)
Disease	nephrosis (biomarker_via_orthology)	NES LRP2	3.59e-03	22	120	2	DOID:2527 (biomarker_via_orthology)
Disease	unipolar depression, bipolar disorder	SYNE1 STARD9 SETBP1 SYNE2	3.84e-03	156	120	4	EFO_0003761, MONDO_0004985

Protein segments in the cluster

Peptide	Gene	Start	Entry
RADASSGDWDTENCQ	ADGRB2	881	O60241
EAAAAAAAREEQSWT	AARD	81	Q4LEZ3
WAEDGEFTSARAVLT	AKAP2	431	Q9Y2D5
ESGDRTSIFWNDVKD	EIF3B	311	P55884
DQRDRWFSDLSDSSF	ANKRD11	836	Q6UB99
RSGDSWEAGDSTVFQ	CSMD2	1396	Q7Z408
FEDGDSSGFWRESSN	DDX4	101	Q9NQI0
SSGFWRESSNDCEDN	DDX4	106	Q9NQI0
DVDSAVEGVVDAAWS	ALDH16A1	286	Q8IZ83
DFAADSWSLAVDSSF	ARHGEF2	211	Q92974
QSIEAADDWFSDDSL	C1orf185	146	Q5T7R7
QGDRSFWNSASFDTE	CNTNAP4	786	Q9C0A0
ASDDSNGLEWENDFV	AP1AR	251	Q63HQ0
VSGSTSREVWEDADF	LINC00469	66	Q8N7U9
AAAADDAWPSRVDAA	DMRTA2	376	Q96SC8
WQSDSSSGSRALDEV	EFCC1	366	Q9HA90
SVSWADDENEASIGS	ARMCX4	1126	Q5H9R4
RFENQTTEEGSWAGA	ARMCX4	1391	Q5H9R4
SEDQATGGSWARSED	ARMCX4	1701	Q5H9R4
DGFSDWMTERVDFTA	ATF5	61	Q9Y2D1
VAAASQAEVESEAGW	P3H1	16	Q32P28
FFEGVDWERLASSTA	CDC42BPG	336	Q6DT37
RWSGNESTDEFSELS	LRCH4	311	O75427
EAERGAWARQSTSAD	PABPC1L2A	171	Q5JQF8
ANVTSATWDFDDEAF	MYLK	1671	Q15746
DQDTTSFDSAWGQES	MFAP1	396	P55081
FTDGRAQDDVSEWAS	MATN2	766	O00339
WSQFDEGSSSQEEEE	MAGEA9	76	P43362
ARESEIEDSDAGSWG	IFNLR1	486	Q8IU57
VNSAGERSREFSWSE	GREB1	1656	Q4ZG55
AEESGSEQATVDAWL	MYO15A	146	Q9UKN7
AAAGDSDSWDADAFS	EIF3J	6	O75822
LWDSGAQETDNERSA	HERC2	316	O95714
WSNSDRSLEQASFDD	GAB3	206	Q8WWW8
TVSSADVDWNAEFSA	LRRC25	26	Q8N386
TFNRELWTTDEGEGD	KIAA2026	851	Q5HYC2
EASSAADGVSAAWEE	LARP4B	71	Q92615
ARSAGADSVQDSWAD	FAM205C	186	A6NFA0
AAWDRDGESDGFADE	NES	1401	P48681
FTQREGDRESWSSGE	NES	1606	P48681
QDFVSGDLADRSTWD	LIAS	46	O43766
CAIWSAEVFEENDGS	KMT2B	1611	Q9UMN6
VDFDSISGRIFWSDA	LRP2	1471	P98164
DQAGSEFENSDVRWV	HSPA12A	186	O43301
ARSESSTEWDLDGFS	KBTBD7	636	Q8WVZ9
SLAEGSWEDFQASVE	TWNK	116	Q96RR1
TFVSTDWDSSGAVND	PAPPA	801	Q13219
FFDDRSVGHTEDAWQ	FOXRED2	511	Q8IWF2
SAAAFWSRDFSDEEQ	KIAA1328	11	Q86T90
TESGWDDTAVVNDLS	PPFIBP2	461	Q8ND30
TSDFEDDWENLLGSE	ETAA1	376	Q9NY74
TWSEEEDGASERGNV	PLEKHG6	666	Q3KR16
DDSVGVEVSSDSFWE	PACSIN2	6	Q9UNF0
ESWRSFEEEFGTASD	CRNKL1	756	Q9BZJ0
TEEQFRANFSSEAGW	ESPL1	1961	Q14674
SFTQGRDSWELETSE	FKBPL	191	Q9UIM3
SESESGTENDQDLWD	HYLS1	116	Q96M11
RVDSSSENSGSDWDS	C6orf47	31	O95873
ADWGQSRDAEEAISQ	COL6A1	216	P12109
GGADDERSSWRNADD	EIF3A	1051	Q14152
DVEFELSADTDGWVA	FRRS1L	131	Q9P0K9
AESSWGDEQADFRCD	GJA5	41	P36382
SEEGWLEFDITATSN	BMP6	301	P22004
EAGDATLASDLQDWA	FOXJ1	401	Q92949
GDVFERDGDEDSWQA	MBLAC1	191	A4D2B0
GDNFETVTWLSDSEV	MBLAC2	111	Q68D91
TFAERSFSEDREEGW	MAST3	721	O60307
SAFHWSDRAEAQGEA	FAM98C	241	Q17RN3
SSTFQIDEDGWRAEQ	LAMC1	516	P11047
AEDVWGDEQSDFTCN	GJA3	41	Q9Y6H8
SVDSAVDSWDGSAID	GRIP1	801	Q9Y3R0
SSADGASERAVAELW	RUBCN	111	Q92622
GLENSSEISADEWSR	PMS1	486	P54277
AWSDVTSFDISDAAA	MYBL1	371	P10243
TATRWDFGDGSAEVD	PKD1	301	P98161
RSHWEGFASDDESNV	FAM149B1	291	Q96BN6
ERESWSGETRQDGES	RBM6	641	P78332
EFARNTSDAWDIGDD	TBC1D22B	61	Q9NU19
FLEIWNDSVDGDSFS	PRUNE2	1621	Q8WUY3
EGQASSVAEQDFWRA	TRAFD1	251	O14545
GEESNESAESSSNWE	SMARCAD1	236	Q9H4L7
FTTEWDNLARSDAES	SYNE1	4256	Q8NF91
QSLQDEAESSEGSWE	SYNE2	5321	Q8WXH0
ADEVQGLAAAAEDWT	FAM83E	61	Q2M2I3
SFSTSVGNEDARTAW	SDCCAG8	51	Q86SQ7
EEASNESGFWSADET	GPRASP2	216	Q96D09
WETASESSDFNERRE	PRRC2C	1496	Q9Y520
SDGLWDAFSNEEAVR	PPM1L	301	Q5SGD2
ASNAWFAAASSEPEE	SLC9A4	41	Q6AI14
DAEDSDGSIASWELR	SMARCD3	171	Q6STE5
FRRGTGQSDDSDIWD	SMN1	21	Q16637
SNEAWEVFRGSSSIA	STARD9	3551	Q9P2P6
SDGSDTFVRRSWDEF	NOXO1	31	Q8NFA2
AEDSLADQAANEWGR	SAA1	91	P0DJI8
DVDDWDNENSSARLF	SPTBN1	26	Q01082
AWDVDIGSDNTDSRA	C12orf71	91	A8MTZ7
ENIDQWFDSRSSDSS	TIGD2	426	Q4W5G0
LASQWGNETDERADT	ZNF197	306	O14709
FGFEADEALDSSWVS	TFPT	221	P0C1Z6
TETAQEATLGRWFDS	TEP1	181	Q99973
AAWIREEGRCSSSDD	PBXIP1	136	Q96AQ6
SIAQDDAGADDWETD	CTTN	11	Q14247
IDVGSEWRTFSNDKA	GTF2B	46	Q00403
GEEASRDVDAWVFSL	SNX18	576	Q96RF0
AQEGAVAFAAWDDDE	TAPBP	231	O15533
SSEELRNLGWDFSQE	SETD2	1251	Q9BYW2
SGTDGFRSENDTNWD	ZNF644	246	Q9H582
AEWEDGERFSFEDSD	ZSWIM8	6	A7E2V4
EDAISDRSDSWSQAA	ZHX2	801	Q9Y6X8
DRSDSWSQAAAEGVS	ZHX2	806	Q9Y6X8
WSQAAAEGVSELAES	ZHX2	811	Q9Y6X8
FEALESSTATDVFWA	F2	71	P00734
VEEGEASDFSLAWDS	ZNF423	6	Q2M1K9
ASDFSLAWDSSVTAA	ZNF423	11	Q2M1K9
AASWAFSTASVAADR	TINAG	241	Q9UJW2
SSDAGNTWRQIFEEE	SORCS1	571	Q8WY21
GRDVDSNSNADSEKW	SETBP1	66	Q9Y6X0
VASGAEDNDEVWSDS	TET2	1836	Q6N021
TAAAGATEEEAVAAW	ZNF579	156	Q8NAF0
ESSGEDEEFWAELQS	WNK4	1126	Q96J92
QSSDALEAWENGERS	TNFSF13	86	O75888
DAFGAAVVTVWDSDA	TRPM4	51	Q8TD43
FGDEAAEQWRFSSAA	TYSND1	151	Q2T9J0
RLQGSETQSSDWEDS	VWA3A	76	A6NCI4
QWEAGEASSDSIELS	TBC1D2	541	Q9BYX2
ESAAWSASGEDSRGQ	TSC2	1426	P49815
DDGEAQAAVRASWEQ	ZAR1	241	Q86SH2
SLDDEGDTQNIDSWF	TPX2	21	Q9ULW0
RNTRSDEDKDGNWDA	ADAMTSL3	66	P82987
SRARDTASGSEAWAE	NAALADL1	701	Q9UQQ1
TDATGSLGEWDVDRN	SLC4A1AP	21	Q9BWU0