Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mRNA regulatory element binding translation repressor activity	CPEB2 CPEB4 CPEB3	3.47e-05	17	76	3	GO:0000900
GeneOntologyBiologicalProcess	negative regulation of cytoplasmic translation	CPEB2 CPEB4 CPEB3	5.66e-06	10	76	3	GO:2000766
GeneOntologyBiologicalProcess	negative regulation of cytoplasmic translational elongation	CPEB2 CPEB3	1.34e-05	2	76	2	GO:1900248
GeneOntologyBiologicalProcess	regulation of cytoplasmic translational elongation	CPEB2 CPEB3	4.01e-05	3	76	2	GO:1900247
GeneOntologyBiologicalProcess	negative regulation of translational elongation	CPEB2 CPEB3	1.33e-04	5	76	2	GO:0045900
GeneOntologyBiologicalProcess	cytoplasmic translational elongation	CPEB2 CPEB3	1.33e-04	5	76	2	GO:0002182
GeneOntologyCellularComponent	collagen type IV trimer	COL4A1 COL4A3	2.04e-04	6	78	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A1 COL4A3	3.79e-04	8	78	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A1 COL4A3	3.79e-04	8	78	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A1 COL4A3	3.79e-04	8	78	2	GO:0098645
Domain	CEBP_ZZ	CPEB2 CPEB4 CPEB3	2.69e-07	4	77	3	IPR032296
Domain	CEBP_ZZ	CPEB2 CPEB4 CPEB3	2.69e-07	4	77	3	PF16366
Domain	RRM_7	CPEB2 CPEB4 CPEB3	2.69e-07	4	77	3	PF16367
Domain	ZINC_FINGER_C2H2_2	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	2.95e-06	775	77	14	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	3.04e-06	777	77	14	PS00028
Domain	-	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	3.72e-06	679	77	13	3.30.160.60
Domain	Znf_C2H2-like	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	4.02e-06	796	77	14	IPR015880
Domain	Znf_C2H2	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	4.58e-06	805	77	14	IPR007087
Domain	zf-C2H2	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	4.65e-06	693	77	13	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	4.72e-06	694	77	13	IPR013087
Domain	ZnF_C2H2	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 POGZ ZNF101 ZNF333 ZNF568 ZNF433	4.78e-06	808	77	14	SM00355
Domain	Growth_fac_rcpt_	ELAPOR2 FAT4 SCUBE1 FBLN2 EPHA2 LRP2	4.48e-05	156	77	6	IPR009030
Domain	KRAB	ZNF8 ZNF793 ZNF596 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	1.12e-04	358	77	8	PS50805
Domain	KRAB	ZNF8 ZNF793 ZNF596 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	1.12e-04	358	77	8	PF01352
Domain	KRAB	ZNF8 ZNF793 ZNF596 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	1.38e-04	369	77	8	SM00349
Domain	KRAB	ZNF8 ZNF793 ZNF596 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	1.41e-04	370	77	8	IPR001909
Domain	Ephrin_rec_like	ELAPOR2 SCUBE1 EPHA2	1.45e-04	25	77	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	ELAPOR2 SCUBE1 EPHA2	1.45e-04	25	77	3	IPR011641
Domain	cEGF	SCUBE1 FBLN2 LRP2	1.64e-04	26	77	3	IPR026823
Domain	cEGF	SCUBE1 FBLN2 LRP2	1.64e-04	26	77	3	PF12662
Domain	C4	COL4A1 COL4A3	2.49e-04	6	77	2	SM00111
Domain	-	COL4A1 COL4A3	2.49e-04	6	77	2	2.170.240.10
Domain	Collagen_VI_NC	COL4A1 COL4A3	2.49e-04	6	77	2	IPR001442
Domain	C4	COL4A1 COL4A3	2.49e-04	6	77	2	PF01413
Domain	NC1_IV	COL4A1 COL4A3	2.49e-04	6	77	2	PS51403
Domain	EGF_CA	FAT4 SCUBE1 FBLN2 LRP2	4.39e-04	86	77	4	PF07645
Domain	EGF_Ca-bd_CS	FAT4 SCUBE1 FBLN2 LRP2	6.92e-04	97	77	4	IPR018097
Domain	EGF_CA	FAT4 SCUBE1 FBLN2 LRP2	7.47e-04	99	77	4	PS01187
Domain	ASX_HYDROXYL	FAT4 SCUBE1 FBLN2 LRP2	7.76e-04	100	77	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 SCUBE1 FBLN2 LRP2	9.65e-04	106	77	4	IPR000152
Domain	CUB	SCUBE1 CSMD1 CSMD2	1.08e-03	49	77	3	PF00431
Domain	CUB	SCUBE1 CSMD1 CSMD2	1.15e-03	50	77	3	SM00042
Domain	-	SCUBE1 CSMD1 CSMD2	1.29e-03	52	77	3	2.60.120.290
Domain	CUB	SCUBE1 CSMD1 CSMD2	1.36e-03	53	77	3	PS01180
Domain	EGF_CA	FAT4 SCUBE1 FBLN2 LRP2	1.62e-03	122	77	4	SM00179
Domain	CUB_dom	SCUBE1 CSMD1 CSMD2	1.68e-03	57	77	3	IPR000859
Domain	EGF-like_Ca-bd_dom	FAT4 SCUBE1 FBLN2 LRP2	1.72e-03	124	77	4	IPR001881
Domain	Semaphorin	SEMA6B SEMA6A	3.04e-03	20	77	2	IPR027231
Domain	zf-MYND	ANKMY1 TDRD1	3.35e-03	21	77	2	PF01753
Domain	Znf_MYND	ANKMY1 TDRD1	3.67e-03	22	77	2	IPR002893
Domain	ZF_MYND_1	ANKMY1 TDRD1	3.67e-03	22	77	2	PS01360
Domain	ZF_MYND_2	ANKMY1 TDRD1	3.67e-03	22	77	2	PS50865
Domain	EGF-like_CS	FAT4 SCUBE1 FBLN2 EPHA2 LRP2	4.47e-03	261	77	5	IPR013032
Domain	EGF_2	FAT4 SCUBE1 FBLN2 EPHA2 LRP2	4.77e-03	265	77	5	PS01186
Domain	Sema	SEMA6B SEMA6A	7.22e-03	31	77	2	SM00630
Domain	Semap_dom	SEMA6B SEMA6A	7.22e-03	31	77	2	IPR001627
Domain	Sema	SEMA6B SEMA6A	7.22e-03	31	77	2	PF01403
Domain	SEMA	SEMA6B SEMA6A	7.22e-03	31	77	2	PS51004
Domain	PSI	SEMA6B SEMA6A	7.68e-03	32	77	2	PF01437
Domain	Plexin_repeat	SEMA6B SEMA6A	7.68e-03	32	77	2	IPR002165
Domain	zf-C2H2_6	ZNF8 ZNF808 ZNF333 ZNF568 ZNF433	9.59e-03	314	77	5	PF13912
Pubmed	CPEB2, a novel putative translational regulator in mouse haploid germ cells.	CPEB2 CPEB4 CPEB3	1.13e-08	3	79	3	12672660
Pubmed	CPEB2-dependent translation of long 3'-UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue.	CPEB2 CPEB4 CPEB3	4.50e-08	4	79	3	30177570
Pubmed	Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus.	CPEB2 CPEB4 CPEB3	4.50e-08	4	79	3	12871996
Pubmed	A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.	CPEB2 CPEB4 CPEB3	1.12e-07	5	79	3	20639532
Pubmed	Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction.	CPEB2 CPEB4 CPEB3	1.34e-06	10	79	3	27810937
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A1 COL4A3 FBLN2	1.84e-06	11	79	3	7500359
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD1 CSMD2	5.09e-06	2	79	2	27890662
Pubmed	The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.	CPEB2 CPEB3	5.09e-06	2	79	2	32440535
Pubmed	The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.	CSMD1 CSMD2	5.09e-06	2	79	2	21439553
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD1 CSMD2	5.09e-06	2	79	2	24408017
Pubmed	Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL.	SEMA6B SEMA6A	5.09e-06	2	79	2	32302524
Pubmed	Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.	CPEB2 CPEB4 CPEB3	8.98e-06	18	79	3	30111840
Pubmed	Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.	COL4A1 COL4A3	1.53e-05	3	79	2	3025878
Pubmed	Identification of two new members of the CSMD gene family.	CSMD1 CSMD2	1.53e-05	3	79	2	12906867
Pubmed	CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion.	CPEB4 CPEB3	1.53e-05	3	79	2	20937770
Pubmed	Identification of an Altered Matrix Signature in Kidney Aging and Disease.	COL4A1 COL4A3	1.53e-05	3	79	2	34049963
Pubmed	Cis interaction between Semaphorin6A and Plexin-A4 modulates the repulsive response to Sema6A.	SEMA6B SEMA6A	1.53e-05	3	79	2	20606624
Pubmed	CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA.	CPEB4 CPEB3	1.53e-05	3	79	2	17024188
Pubmed	Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.	CPEB2 CPEB4	1.53e-05	3	79	2	26398195
Pubmed	Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.	COL4A1 COL4A3	3.05e-05	4	79	2	7827955
Pubmed	Image-based genome-wide siRNA screen identifies selective autophagy factors.	CD163L1 ACTRT1 ALKBH5 FGFBP1 CA7	3.22e-05	159	79	5	22020285
Pubmed	In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.	COL4A1 COL4A3	5.07e-05	5	79	2	9409248
Pubmed	Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.	CPEB4 CPEB3	5.07e-05	5	79	2	21336257
Pubmed	Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.	COL4A1 COL4A3	7.60e-05	6	79	2	10534397
Pubmed	Abnormal basement membrane in the inner ear and the kidney of the Mpv17-/- mouse strain: ultrastructural and immunohistochemical investigations.	COL4A1 COL4A3	7.60e-05	6	79	2	16041630
Pubmed	Stimulation of extracellular matrix components in the normal brain by invading glioma cells.	COL4A1 COL4A3	7.60e-05	6	79	2	9506531
Pubmed	HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.	COL4A1 COL4A3	7.60e-05	6	79	2	7495302
Pubmed	Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.	SEMA6B SEMA6A	7.60e-05	6	79	2	20484647
Pubmed	A tumor derived motility factor that stimulates cell migration on extracellular matrix.	COL4A1 COL4A3	7.60e-05	6	79	2	9673377
Pubmed	Extracellular matrix of the human optic nerve head.	COL4A1 COL4A3	7.60e-05	6	79	2	2426947
Pubmed	Angiogenesis and collagen type IV expression in different endothelial cell culture systems.	COL4A1 COL4A3	7.60e-05	6	79	2	23551189
Pubmed	Monoclonal antibody to human basement membrane collagen type IV.	COL4A1 COL4A3	7.60e-05	6	79	2	6811420
Pubmed	Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.	COL4A1 COL4A3	7.60e-05	6	79	2	11732842
Pubmed	Developmental distribution of collagen IV isoforms and relevance to ocular diseases.	COL4A1 COL4A3	7.60e-05	6	79	2	19275937
Pubmed	Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.	COL4A1 COL4A3	7.60e-05	6	79	2	6988303
Pubmed	Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.	COL4A1 COL4A3	7.60e-05	6	79	2	6389236
Pubmed	Collagen IV in the developing lens capsule.	COL4A1 COL4A3	7.60e-05	6	79	2	12225806
Pubmed	Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.	COL4A1 COL4A3	1.06e-04	7	79	2	10639489
Pubmed	Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.	COL4A1 COL4A3	1.06e-04	7	79	2	7521231
Pubmed	Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.	COL4A1 COL4A3	1.06e-04	7	79	2	11711546
Pubmed	Regulation of protease nexin-1 target protease specificity by collagen type IV.	COL4A1 COL4A3	1.06e-04	7	79	2	8006028
Pubmed	Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.	COL4A1 COL4A3	1.06e-04	7	79	2	17418794
Pubmed	Corneal cell proteins and ocular surface pathology.	COL4A1 COL4A3	1.06e-04	7	79	2	10416788
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A1 COL4A3	1.06e-04	7	79	2	10716744
Pubmed	Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.	COL4A1 COL4A3	1.06e-04	7	79	2	1724753
Pubmed	Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.	COL4A1 COL4A3	1.41e-04	8	79	2	10382266
Pubmed	Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.	COL4A1 COL4A3	1.41e-04	8	79	2	3997552
Pubmed	Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.	COL4A1 COL4A3	1.41e-04	8	79	2	29422532
Pubmed	Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.	COL4A1 COL4A3	1.41e-04	8	79	2	10970885
Pubmed	Mice develop normally without tenascin.	COL4A1 COL4A3	1.41e-04	8	79	2	1383086
Pubmed	Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.	COL4A1 COL4A3	1.41e-04	8	79	2	1377218
Pubmed	Molecular properties of wild-type and mutant betaIG-H3 proteins.	COL4A1 COL4A3	1.41e-04	8	79	2	11867580
Pubmed	Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance.	SEMA6B SEMA6A	1.82e-04	9	79	2	15814794
Pubmed	MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?	COL4A1 COL4A3	1.82e-04	9	79	2	9878537
Pubmed	Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.	COL4A1 COL4A3	1.82e-04	9	79	2	8562707
Pubmed	Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.	COL4A1 COL4A3	1.82e-04	9	79	2	12101409
Pubmed	Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.	COL4A1 COL4A3	1.82e-04	9	79	2	10880400
Pubmed	Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.	COL4A1 COL4A3	1.82e-04	9	79	2	8995276
Pubmed	Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.	COL4A1 COL4A3	2.27e-04	10	79	2	9136074
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	COL4A1 COL4A3	2.27e-04	10	79	2	9415455
Pubmed	Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.	COL4A1 COL4A3	2.76e-04	11	79	2	17339318
Pubmed	Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.	COL4A1 COL4A3	2.76e-04	11	79	2	14998921
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	FOLR1 LRP2	2.76e-04	11	79	2	24639464
Pubmed	Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.	COL4A1 COL4A3	2.76e-04	11	79	2	9731539
Pubmed	Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst.	COL4A1 LRP2	2.76e-04	11	79	2	18083160
Pubmed	Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.	COL4A1 COL4A3	3.31e-04	12	79	2	8918877
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	SEMA6B SEMA6A	3.31e-04	12	79	2	24179230
Pubmed	Basement membrane fragility underlies embryonic lethality in fukutin-null mice.	COL4A1 COL4A3	3.31e-04	12	79	2	15837576
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	COL4A1 COL4A3	3.31e-04	12	79	2	26794322
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A1 COL4A3	3.31e-04	12	79	2	12180907
Pubmed	Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.	COL4A1 COL4A3	3.31e-04	12	79	2	16024816
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A1 COL4A3	3.91e-04	13	79	2	9833687
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A3 FBLN2	3.91e-04	13	79	2	12682087
Pubmed	Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.	JARID2 POGZ ZNF568	4.06e-04	63	79	3	25680957
Pubmed	Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin.	SEMA6B SEMA6A	4.55e-04	14	79	2	30735130
Pubmed	Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.	COL4A1 COL4A3	4.55e-04	14	79	2	12878203
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A1 COL4A3	5.25e-04	15	79	2	10625553
Pubmed	A single-cell atlas of mouse lung development.	COL4A1 COL4A3	5.25e-04	15	79	2	34927678
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A1 COL4A3	5.25e-04	15	79	2	9264260
Pubmed	Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.	COL4A1 COL4A3	5.25e-04	15	79	2	10706142
Pubmed	Balance between BDNF and Semaphorins gates the innervation of the mammary gland.	SEMA6B SEMA6A	5.99e-04	16	79	2	30628891
Pubmed	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.	CAV3 TF	5.99e-04	16	79	2	22792322
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	COL4A1 COL4A3	5.99e-04	16	79	2	15878328
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA6B SEMA6A	5.99e-04	16	79	2	22632726
Pubmed	Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse.	COL4A1 IFITM3	5.99e-04	16	79	2	27435625
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FAT4 ZNF142 ACAD11 IRF2BP1 YY2 CSMD2 ZNF568	6.26e-04	638	79	7	31182584
Pubmed	New GPCRs from a human lingual cDNA library.	OR5P3 OR10A5	6.78e-04	17	79	2	11705801
Pubmed	Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.	COL4A1 COL4A3	7.61e-04	18	79	2	9160753
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL4A1 COL4A3 FBLN2	7.88e-04	79	79	3	18757743
Pubmed	Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.	SCUBE1 TPCN1	8.50e-04	19	79	2	23149075
Pubmed	Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.	COL4A1 COL4A3	8.50e-04	19	79	2	15689378
Pubmed	Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.	SEMA6B SEMA6A	8.50e-04	19	79	2	15051154
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF8 POGZ ZNF568	9.09e-04	83	79	3	20562864
Pubmed	The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2.	COL4A1 COL4A3	1.04e-03	21	79	2	23325811
Pubmed	Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development.	TM4SF4 DISP2	1.04e-03	21	79	2	20003319
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	COL4A1 COL4A3	1.04e-03	21	79	2	27856617
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5P3 OR2T6 OR5G3 OR2A25 OR10A5	1.08e-03	340	79	5	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5P3 OR2T6 OR5G3 OR2A25 OR10A5	1.08e-03	340	79	5	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5P3 OR2T6 OR5G3 OR2A25 OR10A5	1.12e-03	343	79	5	32295537
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	ZNF793 ZNF333	1.14e-03	22	79	2	31403225
Interaction	FBLN2 interactions	COL4A1 ZNF8 COL4A3 ZNF142 FBLN2 ZNF101	1.79e-07	66	76	6	int:FBLN2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF8 ZBTB37 ZNF793 ZNF142 ZNF35 ZFP3 ZNF596 YY2 ZNF808 ZNF101 ZNF333 ZNF568 ZNF433	2.14e-07	718	56	13	28
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA6B SEMA6A	1.73e-03	20	56	2	736
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LYPD6B PLA1A SMPD3 TF FAM3D FGFBP1	1.52e-06	200	79	6	df90b67490cd649de3e3a713762ffbc34a698899
ToppCell	AT1-AT2_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 OR5P3 COL4A3 SCUBE1 FAM20A	8.35e-06	155	79	5	010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB37 FAT4 YY2 USP54 FAM3D	1.54e-05	176	79	5	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 FOLR1 LRP2 NEIL3 SMPD3	1.54e-05	176	79	5	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 FOLR1 LRP2 NEIL3 SMPD3	1.54e-05	176	79	5	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL4A3 FBLN2 FOLR1 LRP2 SMPD3	1.86e-05	183	79	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOLR1 EPHA2 TF FAM3D FGFBP1	2.07e-05	187	79	5	71d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell	droplet-Tongue-nan-24m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TM4SF4 CPEB3 FAM20A FAM3D FGFBP1	2.23e-05	190	79	5	86ab845a7fae2111c0b01e1aec235e19c4c0ef5c
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TM4SF4 CPEB3 FAM20A FAM3D FGFBP1	2.23e-05	190	79	5	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	(4)_Endothelial_cells-(41)_EC-arteriolar\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL4A1 FBLN2 IFITM3 SEMA6A CA7	2.29e-05	191	79	5	718c83046668a7c33bd8319b45c56f8edb34cfe7
ToppCell	facs-Thymus-Epithelium-24m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SEMA6B FBLN2 IFITM3 CA7	2.34e-05	192	79	5	39afea574725ce0c67afdd79facdb34f819a828d
ToppCell	facs-Thymus-Epithelium-24m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SEMA6B FBLN2 IFITM3 CA7	2.34e-05	192	79	5	597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCell	facs-Thymus-Epithelium-24m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SEMA6B FBLN2 IFITM3 CA7	2.34e-05	192	79	5	bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCell	facs-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 LYPD6B FOLR1 LRP2 FAM3D	2.46e-05	194	79	5	3701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell	facs-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 LYPD6B FOLR1 LRP2 FAM3D	2.46e-05	194	79	5	65f9bf126be26114c2c3f4c46d48318986212a92
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	ELAPOR2 EPHA2 LRP2 SMPD3 FAM20A	2.46e-05	194	79	5	784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 PLA1A IFITM3 LRP2 CSMD1	2.59e-05	196	79	5	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 PLA1A IFITM3 LRP2 CSMD1	2.59e-05	196	79	5	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A3 IFITM3 FOLR1 USP54 FAM20A	2.59e-05	196	79	5	784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCell	distal-2-Hematologic-EREG+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLIPR1 SEMA6B JARID2 LIMS1 PTAFR	2.65e-05	197	79	5	6fcca7c071e35786b715adeb18be317d34315d7e
ToppCell	Parenchyma_Control_(B.)-Immune-TX-MoAM-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	JARID2 VRK3 MTMR8 CPEB3 ZNF333	2.65e-05	197	79	5	dc1c55e3aacc9d60d0f111c2f20f150ca296f011
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LYPD6B FOLR1 EPHA2 FAM3D FGFBP1	2.65e-05	197	79	5	ac9c0c25cfeaabd53d332982c73fc6c47b0c6478
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LYPD6B FOLR1 EPHA2 FAM3D FGFBP1	2.65e-05	197	79	5	b57d2e3413ef6dd1da56c45087926f2f3eab876c
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ELAPOR2 PLA1A EPHA2 USP54 TF	2.72e-05	198	79	5	aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell	5'-Adult-Distal_Rectal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN2 IFITM3 FAM3D FGFBP1 CA7	2.72e-05	198	79	5	db26c20321f9ab102d6484f22ddb2bde684067b1
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	JARID2 CD163L1 PTAFR CSMD1 FAM20A	2.78e-05	199	79	5	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	(04)_Interm._basal>secr.-(1)_GFP\|(04)_Interm._basal>secr. / shred by cell type by condition	JARID2 EPHA2 RNPEPL1 FAM3D FGFBP1	2.78e-05	199	79	5	7a0d40d4679dc373829d67693851428f41c8b0d6
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 JARID2 FAT4 LIMS1 POGZ	2.78e-05	199	79	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ELAPOR2 FOLR1 EPHA2 LRP2 FAM20A	2.85e-05	200	79	5	23088edc62bf7d4db890937bfd7925dc316fcc76
ToppCell	(05)_Ciliated-(2)_48hpi\|(05)_Ciliated / shred by cell type and Timepoint	SEMA6B COL4A3 PLA1A FOLR1	7.04e-05	124	79	4	fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A3 LIPT1 PLA1A EPHA2	1.04e-04	137	79	4	9324b55eac55e0cc1e8e450a4b5374d12e9587a3
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A3 LIPT1 PLA1A EPHA2	1.04e-04	137	79	4	032f8409d0d179e254c8ff632afbda78852a9889
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A3 LIPT1 PLA1A EPHA2	1.04e-04	137	79	4	265a4a50e48b13c8b3b0730f818235f71fbd6baa
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NXNL1 ZNF142 MKLN1 FAM20A	1.29e-04	145	79	4	c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EPHA2 LRP2 SMPD3 TDRD1	1.32e-04	146	79	4	bee5074c29b132180d35f57d307e342efa9b8cd1
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	LOXHD1 SMPD3 CSMD2 CA7	1.36e-04	147	79	4	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 COL4A3 ZNF596	1.66e-04	60	79	3	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 COL4A3 ZNF596	1.66e-04	60	79	3	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CPEB2 NEIL3 USP54 CA7	1.71e-04	156	79	4	fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ELAPOR2 SCUBE1 YY2 ZNF433	1.84e-04	159	79	4	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	LPS-IL1RA-Epithelial_airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	1.93e-04	161	79	4	472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LYPD6B LHX4 ZFP3 FAM3D	1.97e-04	162	79	4	075f73ff10e1a7f5695e014e47acc4db513e9cfb
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.07e-04	164	79	4	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A3 LYPD6B FOLR1 LRP2	2.07e-04	164	79	4	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF596 NEIL3 SMPD3 CAV3	2.07e-04	164	79	4	1642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.07e-04	164	79	4	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A3 LYPD6B FOLR1 LRP2	2.07e-04	164	79	4	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF596 NEIL3 SMPD3 CAV3	2.07e-04	164	79	4	25758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCell	LPS_only-Epithelial_airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.07e-04	164	79	4	56e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A3 LYPD6B FOLR1 LRP2	2.07e-04	164	79	4	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	facs-Trachea-nan-18m-Epithelial-mucus_secreting_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 LYPD6B FOLR1 LRP2	2.12e-04	165	79	4	7e7643834ed483aec04f513cca38d6367fda9ff8
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.12e-04	165	79	4	1a114eacaab598f755a173a3fed842ba91f689dd
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.12e-04	165	79	4	9cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell	LPS-antiTNF-Epithelial_airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.16e-04	166	79	4	eb942ed68677e55c46cb039046f45686d4062d7c
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.16e-04	166	79	4	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.16e-04	166	79	4	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.32e-04	169	79	4	8c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B PLA1A TF FAM3D	2.32e-04	169	79	4	86041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOLR1 FAM3D FGFBP1 CA7	2.42e-04	171	79	4	042701dd87676d41d8e7e7cce0e1ffc2331b248d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CAV3 CSMD1 CSMD2 TF	2.42e-04	171	79	4	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOLR1 FAM3D FGFBP1 CA7	2.42e-04	171	79	4	74d7811a57837d99932a9b86f2d08e8574a819e6
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZBTB37 ZNF793 CACFD1 SMPD3	2.48e-04	172	79	4	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	LYPD6B FBLN2 MC1R DISP2	2.65e-04	175	79	4	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A3 ELAPOR2 LOXHD1 SEMA6A	2.76e-04	177	79	4	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOLR1 LRP2 SMPD3 FGFBP1	2.82e-04	178	79	4	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LYPD6B FBLN2 FOLR1 SMPD3	2.88e-04	179	79	4	adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SEMA6B SEMA6A FAM3D AGBL3	2.88e-04	179	79	4	040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 LYPD6B MKLN1 FAM20A	2.95e-04	180	79	4	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN2 ZNF35 PLA1A SMPD3	2.95e-04	180	79	4	c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B SCUBE1 FBLN2 PLA1A	2.95e-04	180	79	4	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	FOLR1 EPHA2 FAM3D FGFBP1	2.95e-04	180	79	4	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	AT1_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	COL4A3 SCUBE1 LOXHD1 FOLR1	2.95e-04	180	79	4	ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCell	facs-Thymus-Epithelium-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 IFITM3 SEMA6A CA7	3.01e-04	181	79	4	bce56e12ab93693c9c04fa6aad8f2e1dff0c4d45
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LYPD6B FOLR1 CACFD1 FAM3D	3.07e-04	182	79	4	94e70746e35a3062015d4b83ee545f4f84f47420
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 FOLR1 LRP2 SMPD3	3.07e-04	182	79	4	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLA1A EPHA2 USP54 TF	3.14e-04	183	79	4	5f2db95d44b7de68779de098892892af540fd431
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 CSMD1 TF FAM3D	3.14e-04	183	79	4	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR93 FOLR1 LRP2 DNAI3	3.14e-04	183	79	4	6ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 FBLN2 LOXHD1 IFITM3	3.14e-04	183	79	4	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A3 PLA1A EPHA2 USP54	3.14e-04	183	79	4	06ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 FBLN2 LOXHD1 IFITM3	3.14e-04	183	79	4	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR93 FOLR1 LRP2 DNAI3	3.14e-04	183	79	4	18040d0653286071df959513c63d94b555a5d00a
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 COL4A3 SCUBE1 USP54	3.14e-04	183	79	4	6821dca076318115d360ff426eb1218cfe104063
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 LOXHD1 LRP2 CSMD1	3.20e-04	184	79	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL4A1 FBLN2 IFITM3 PTAFR	3.20e-04	184	79	4	7e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 LOXHD1 LRP2 CSMD1	3.20e-04	184	79	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 LOXHD1 LRP2 CSMD1	3.20e-04	184	79	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	FOLR1 EPHA2 FAM3D FGFBP1	3.27e-04	185	79	4	9a793e6016295a63820e9d7563f195494ac692e7
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	SEMA6B LYPD6B FBLN2 DISP2	3.27e-04	185	79	4	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 FBLN2 CAV3 CA7	3.27e-04	185	79	4	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	COPD-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	FOLR1 EPHA2 FAM3D FGFBP1	3.34e-04	186	79	4	d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEMA6B IFITM3 MC1R FAM20A	3.34e-04	186	79	4	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN2 EPHA2 SMPD3 FAM20A	3.34e-04	186	79	4	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 COL4A3 FBLN2 IFITM3	3.34e-04	186	79	4	cc94e0c5d1665d2ea2bb871ad79d8e1ec2249fb5
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEMA6B IFITM3 MC1R FAM20A	3.34e-04	186	79	4	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SMPD3 CSMD1 FGFBP1 CA7	3.40e-04	187	79	4	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	Control-Epithelial-ATI\|Control / Disease state, Lineage and Cell class	COL4A1 COL4A3 SCUBE1 FOLR1	3.40e-04	187	79	4	fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 COL4A3 FAT4 SEMA6A	3.47e-04	188	79	4	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B LYPD6B FBLN2 IFITM3	3.47e-04	188	79	4	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 FOLR1 LRP2 FGFBP1	3.54e-04	189	79	4	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
Disease	aspartate aminotransferase to alanine aminotransferase ratio	DPAGT1 JARID2 EPHA2 TM4SF4 ZNF101	3.21e-04	239	73	5	EFO_0010934
Disease	collagen disease (implicated_via_orthology)	COL4A1 COL4A3	3.92e-04	12	73	2	DOID:854 (implicated_via_orthology)
Disease	glomerulonephritis (implicated_via_orthology)	COL4A3 PTAFR	8.02e-04	17	73	2	DOID:2921 (implicated_via_orthology)
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	COL4A1 CSMD1	1.35e-03	22	73	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	insular cortex volume measurement	LOXHD1 FBXO47	1.48e-03	23	73	2	EFO_0010309
Disease	Nephrotic Syndrome	COL4A1 TF	2.04e-03	27	73	2	C0027726
Disease	Carcinoma, Basal Cell	MC1R ACTRT1	2.35e-03	29	73	2	C4721806

Protein segments in the cluster

Peptide	Gene	Start	Entry
FKAEIGQPCCAFFAG	TDRD1	761	Q9BXT4
NCPDKFSFSACKFNV	AGBL3	496	Q8NEM8
ALGKNCPFLQCVDFS	AMN1	161	Q8IY45
NKPSCVFSCFFNFTA	CSMD1	576	Q96PZ7
KPGCVFSCFFNFTSP	CSMD2	571	Q7Z408
PFLFCNVNDVCNFAS	COL4A3	1501	Q01955
FSDSALCFGCKFQFK	ALKBH5	221	Q6P6C2
APFCCQFIEFANTVA	CACFD1	76	Q9UGQ2
QNFPGSFNCVCKTGY	FAT4	3916	Q6V0I7
EFSCVFAGNPTSCLK	FGFBP1	91	Q14512
CKQLGCPFSFAMFRF	CD163L1	86	Q9NR16
FCFKFCPSDPNIIAG	DNAI3	401	Q8IWG1
FFQSLCCFFGPEKNC	DISP2	1106	A7MBM2
TGKCFFAPDVFNCQA	ACAD11	456	Q709F0
PFLFCNINNVCNFAS	COL4A1	1501	P02462
PTCGCIFKNFNLFLA	MC1R	271	Q01726
CPANYFAFKICSGAA	FAM3D	61	Q96BQ1
CAVQFCPKVSGFDAL	GLIPR1	151	P48060
FFVCPLGKEKQCNFF	NEIL3	576	Q8TAT5
VFSCQFGNFLGNCQK	MTMR8	431	Q96EF0
SLFNTLFMNPCCLGF	IFITM3	61	Q01628
FQLLCNCQVPAAGFK	LIPT1	11	Q9Y234
GNVYFFNCDCLIPLK	LOXHD1	1906	Q8IVV2
FPFLNCFVKEQCKAF	DPAGT1	76	Q9H3H5
QPGFLCQNTKGSFYC	FBLN2	776	P98095
NKCSGFFFGVICAVF	OR2T6	21	Q8NHC8
FFKRFGTKCTACQQG	LHX4	81	Q969G2
FSCACATGFKLNPDN	LRP2	2041	P98164
GKSFCFATANVCLLP	SMPD3	121	Q9NY59
GTFSNKPGSFNCQVC	ELAPOR2	296	A8MWY0
QENPFCRFKAVGYSC	NUP54	166	Q7Z3B4
GGKFAPFFCANVTCL	CPEB2	536	Q7Z5Q1
GKFAPFFCANVTCLQ	CPEB3	646	Q8NE35
SLFNTLFMNPCCLGF	nan	61	C9JQL5
DACQACSPGFFKFEA	EPHA2	271	P29317
QGQIPFFKFCYQCGR	ANKMY1	871	Q9P2S6
RTFCNPLFAALGQVC	CAV3	126	P56539
LTEVSCFKFNGCAAP	FBXO47	141	Q5MNV8
AICFPFVFNSVKNGS	GPR85	71	P60893
AQFSCFNPKCLLPAS	CA7	176	P43166
GGKFAPFFCANVTCL	CPEB4	676	Q17RY0
FFSADGFKPCQACPV	SCUBE1	691	Q8IWY4
FNKCAVGAACQPFHF	FOLR1	166	P15328
FCFPCSREFIKAQGP	IRF2BP1	526	Q8IU81
SFPFCGTNKVNHFFC	OR10A5	166	Q9H207
SFCGPQKLNHFFCEI	OR2A25	166	A4D2G3
IFTFCLPFCGSNIIN	OR5G3	161	P0C626
QFVVCFPGSFVSKVC	JARID2	1006	Q92833
CNRSFFPCFDTPAVK	RNPEPL1	201	Q9HAU8
SEPQFSGLFAFNCQC	MKLN1	421	Q9UL63
PKFLCNVAGCLFFIN	PTAFR	86	P25105
FVSPASNVCFFAKCP	FAM20A	306	Q96MK3
CPYCLKVFKNGNAFQ	POGZ	621	Q7Z3K3
FVCAQCFQQFPEGLF	LIMS1	36	P48059
LSFCGPNKVNHFFCD	OR5P3	166	Q8WZ94
LFASGFNFPCILNKA	ACTRT1	196	Q8TDG2
KAFLAGRCLDCFNPF	PLA1A	286	Q53H76
LFVCGSNAFNPVCAN	SEMA6B	141	Q9H3T3
PFACNDCGKAFTQSA	ZNF35	361	P13682
RPFECFFCGKAFTQK	ZNF793	281	Q6ZN11
FLCFSQLPNAVCFGG	nan	86	Q96MF0
VCPLCGKAFSKFFNL	ZNF596	476	Q8TC21
CHVCGKSFPFQAILN	ZBTB37	431	Q5TC79
PFKCNQCGQDFSHKF	ZNF568	221	Q3ZCX4
EKAVANFFSGSCAPC	TF	166	P02787
LLFFGAGACPQCQAF	NXNL1	36	Q96CM4
ALFVCGTNAFNPSCR	SEMA6A	131	Q9H2E6
FVCPFDVCNRKFAQS	YY2	341	O15391
FPCNESGKAFNCSSL	ZNF808	231	Q8N4W9
SIQAAFKFCPYCGNS	VRK3	11	Q8IV63
PFECSQCGKTFTRNF	ZNF333	421	Q96JL9
MEFFCGIVFPNCCNT	TPCN1	586	Q9ULQ1
CKVCGKAFNSPNLFQ	ZNF101	171	Q8IZC7
ALPQGCFCQSIHFLK	WDR93	451	Q6P2C0
PFKCNQCGKCFIQSS	ZNF8	466	P17098
FEQGKFHCNSCPFLC	ZNF142	1021	P52746
ACKECGKPFSNFSFF	ZNF433	451	Q8N7K0
FPALVFLGLKNNDCC	TM4SF4	61	P48230
PFACNECGKAFIQSS	ZFP3	196	Q96NJ6
FCALKGIFNQFQCSS	USP54	76	Q70EL1
FPNSFKCFTCENAGD	LYPD6B	56	Q8NI32