| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | sodium ion binding | 4.10e-09 | 14 | 30 | 4 | GO:0031402 | |
| GeneOntologyMolecularFunction | alkali metal ion binding | 6.05e-08 | 26 | 30 | 4 | GO:0031420 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 7.77e-06 | 26 | 30 | 3 | GO:0005248 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 3.16e-05 | 627 | 30 | 7 | GO:0022890 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SLC30A7 HRH1 SLC45A2 SLC7A3 ATP1A2 SLC16A2 SCN1A SCN8A SCN9A | 3.94e-05 | 1180 | 30 | 9 | GO:0022857 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 4.55e-05 | 664 | 30 | 7 | GO:0008324 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 5.70e-05 | 465 | 30 | 6 | GO:0046873 | |
| GeneOntologyMolecularFunction | sodium channel activity | 6.44e-05 | 52 | 30 | 3 | GO:0005272 | |
| GeneOntologyMolecularFunction | transporter activity | SLC30A7 HRH1 SLC45A2 SLC7A3 ATP1A2 SLC16A2 SCN1A SCN8A SCN9A | 7.85e-05 | 1289 | 30 | 9 | GO:0005215 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 1.05e-04 | 758 | 30 | 7 | GO:0015318 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 1.20e-04 | 171 | 30 | 4 | GO:0015081 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 1.39e-04 | 793 | 30 | 7 | GO:0015075 | |
| GeneOntologyMolecularFunction | odorant binding | 9.00e-04 | 127 | 30 | 3 | GO:0005549 | |
| GeneOntologyMolecularFunction | olfactory receptor activity | 3.76e-03 | 431 | 30 | 4 | GO:0004984 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 9.54e-03 | 884 | 30 | 5 | GO:0004930 | |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 1.08e-02 | 105 | 30 | 2 | GO:0015171 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 1.80e-07 | 36 | 29 | 4 | GO:0086010 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 6.47e-06 | 87 | 29 | 4 | GO:0086001 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 8.44e-06 | 93 | 29 | 4 | GO:0086003 | |
| GeneOntologyBiologicalProcess | transmission of nerve impulse | 1.76e-05 | 112 | 29 | 4 | GO:0019226 | |
| GeneOntologyBiologicalProcess | membrane depolarization | 2.39e-05 | 121 | 29 | 4 | GO:0051899 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 2.89e-05 | 127 | 29 | 4 | GO:0070252 | |
| GeneOntologyBiologicalProcess | circulatory system process | 5.48e-05 | 733 | 29 | 7 | GO:0003013 | |
| GeneOntologyBiologicalProcess | actin filament-based movement | 5.98e-05 | 153 | 29 | 4 | GO:0030048 | |
| GeneOntologyBiologicalProcess | amino acid import across plasma membrane | 7.32e-05 | 58 | 29 | 3 | GO:0089718 | |
| GeneOntologyBiologicalProcess | sensory perception | 8.36e-05 | 1072 | 29 | 8 | GO:0007600 | |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 8.41e-05 | 167 | 29 | 4 | GO:0060048 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 8.94e-05 | 62 | 29 | 3 | GO:0086002 | |
| GeneOntologyBiologicalProcess | neuronal action potential | 9.38e-05 | 63 | 29 | 3 | GO:0019228 | |
| GeneOntologyBiologicalProcess | neuronal action potential propagation | 1.25e-04 | 12 | 29 | 2 | GO:0019227 | |
| GeneOntologyBiologicalProcess | action potential propagation | 1.25e-04 | 12 | 29 | 2 | GO:0098870 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | 1.34e-04 | 582 | 29 | 6 | GO:0050906 | |
| GeneOntologyBiologicalProcess | action potential | 1.72e-04 | 201 | 29 | 4 | GO:0001508 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 1.96e-04 | 208 | 29 | 4 | GO:0035725 | |
| GeneOntologyBiologicalProcess | striated muscle contraction | 2.30e-04 | 217 | 29 | 4 | GO:0006941 | |
| GeneOntologyBiologicalProcess | transport across blood-brain barrier | 2.45e-04 | 87 | 29 | 3 | GO:0150104 | |
| GeneOntologyBiologicalProcess | vascular transport | 2.53e-04 | 88 | 29 | 3 | GO:0010232 | |
| GeneOntologyBiologicalProcess | detection of stimulus | 4.30e-04 | 722 | 29 | 6 | GO:0051606 | |
| GeneOntologyBiologicalProcess | sodium ion transport | 5.65e-04 | 275 | 29 | 4 | GO:0006814 | |
| GeneOntologyBiologicalProcess | adult locomotory behavior | 5.69e-04 | 116 | 29 | 3 | GO:0008344 | |
| GeneOntologyBiologicalProcess | amino acid transmembrane transport | 6.28e-04 | 120 | 29 | 3 | GO:0003333 | |
| GeneOntologyBiologicalProcess | heart contraction | 7.63e-04 | 298 | 29 | 4 | GO:0060047 | |
| GeneOntologyBiologicalProcess | heart process | 8.73e-04 | 309 | 29 | 4 | GO:0003015 | |
| GeneOntologyBiologicalProcess | vascular process in circulatory system | 1.30e-03 | 344 | 29 | 4 | GO:0003018 | |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | 1.54e-03 | 922 | 29 | 6 | GO:0098662 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 1.79e-06 | 17 | 30 | 3 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 9.50e-06 | 29 | 30 | 3 | GO:0034706 | |
| GeneOntologyCellularComponent | node of Ranvier | 3.72e-04 | 20 | 30 | 2 | GO:0033268 | |
| GeneOntologyCellularComponent | axon initial segment | 7.89e-04 | 29 | 30 | 2 | GO:0043194 | |
| HumanPheno | Complex febrile seizure | 2.12e-08 | 16 | 11 | 4 | HP:0011172 | |
| HumanPheno | Abnormal facial expression | 8.41e-07 | 185 | 11 | 6 | HP:0005346 | |
| HumanPheno | Focal automatism seizure | 1.63e-06 | 12 | 11 | 3 | HP:0032898 | |
| HumanPheno | Choreoathetosis | 3.11e-06 | 123 | 11 | 5 | HP:0001266 | |
| HumanPheno | Facial tics | 3.36e-06 | 15 | 11 | 3 | HP:0011468 | |
| HumanPheno | Focal sensory seizure | 1.13e-05 | 22 | 11 | 3 | HP:0011157 | |
| HumanPheno | Athetosis | 1.36e-05 | 166 | 11 | 5 | HP:0002305 | |
| HumanPheno | Focal hemiclonic seizure | 1.68e-05 | 25 | 11 | 3 | HP:0006813 | |
| HumanPheno | Epileptic aura | 1.68e-05 | 25 | 11 | 3 | HP:0033348 | |
| HumanPheno | Clonic seizure | 1.80e-05 | 81 | 11 | 4 | HP:0020221 | |
| HumanPheno | Alien limb phenomenon | 2.54e-05 | 4 | 11 | 2 | HP:0032506 | |
| HumanPheno | Focal manual automatism seizure | 2.54e-05 | 4 | 11 | 2 | HP:0032900 | |
| HumanPheno | Focal pedal automatism seizure | 2.54e-05 | 4 | 11 | 2 | HP:0032901 | |
| HumanPheno | Dissociated sensory loss | 2.54e-05 | 4 | 11 | 2 | HP:0010835 | |
| HumanPheno | Progressive gait ataxia | 2.95e-05 | 30 | 11 | 3 | HP:0007240 | |
| HumanPheno | Progressive ataxia | 2.95e-05 | 30 | 11 | 3 | HP:0001329 | |
| HumanPheno | Seesaw nystagmus | 4.22e-05 | 5 | 11 | 2 | HP:0012044 | |
| HumanPheno | Spontaneous pain sensation | 4.22e-05 | 5 | 11 | 2 | HP:0010833 | |
| HumanPheno | Generalized clonic seizure | 4.32e-05 | 34 | 11 | 3 | HP:0011169 | |
| HumanPheno | Abnormality of temperature sensation | 4.32e-05 | 34 | 11 | 3 | HP:0100772 | |
| HumanPheno | Impaired temperature sensation | 4.32e-05 | 34 | 11 | 3 | HP:0010829 | |
| HumanPheno | Limitation of neck motion | 5.15e-05 | 36 | 11 | 3 | HP:0005986 | |
| HumanPheno | Disturbance of facial expression | 5.15e-05 | 36 | 11 | 3 | HP:0005324 | |
| HumanPheno | Abnormal neck physiology | 5.15e-05 | 36 | 11 | 3 | HP:0025669 | |
| HumanPheno | Facial palsy | 6.92e-05 | 232 | 11 | 5 | HP:0010628 | |
| HumanPheno | Abnormal seventh cranial physiology | 7.07e-05 | 233 | 11 | 5 | HP:0010827 | |
| HumanPheno | Focal non-motor seizure | 7.09e-05 | 40 | 11 | 3 | HP:0032679 | |
| HumanPheno | Amaurosis fugax | 7.64e-05 | 41 | 11 | 3 | HP:0100576 | |
| HumanPheno | EEG with focal epileptiform discharges | 7.96e-05 | 118 | 11 | 4 | HP:0011185 | |
| HumanPheno | Focal clonic seizure | 8.22e-05 | 42 | 11 | 3 | HP:0002266 | |
| HumanPheno | Chorea | 9.53e-05 | 248 | 11 | 5 | HP:0002072 | |
| HumanPheno | First dorsal interossei muscle weakness | 1.18e-04 | 8 | 11 | 2 | HP:0003392 | |
| HumanPheno | Photosensitive myoclonic seizure | 1.18e-04 | 8 | 11 | 2 | HP:0001327 | |
| HumanPheno | Cyanotic episode | 1.18e-04 | 8 | 11 | 2 | HP:0200048 | |
| HumanPheno | Focal motor seizure | 1.20e-04 | 131 | 11 | 4 | HP:0011153 | |
| HumanPheno | Weakness of facial musculature | 1.41e-04 | 269 | 11 | 5 | HP:0030319 | |
| HumanPheno | Bilateral tonic-clonic seizure with focal onset | 1.56e-04 | 52 | 11 | 3 | HP:0007334 | |
| HumanPheno | Paresthesia | 1.73e-04 | 144 | 11 | 4 | HP:0003401 | |
| HumanPheno | Infection-related seizure | 1.78e-04 | 145 | 11 | 4 | HP:0032892 | |
| HumanPheno | Seizure precipitated by febrile infection | 1.78e-04 | 145 | 11 | 4 | HP:0032894 | |
| HumanPheno | Febrile seizure (within the age range of 3 months to 6 years) | 1.78e-04 | 145 | 11 | 4 | HP:0002373 | |
| HumanPheno | Gaze-evoked nystagmus | 1.85e-04 | 55 | 11 | 3 | HP:0000640 | |
| HumanPheno | EEG with generalized sharp slow waves | 1.89e-04 | 10 | 11 | 2 | HP:0011199 | |
| HumanPheno | Decreased vigilance | 1.89e-04 | 10 | 11 | 2 | HP:0032044 | |
| HumanPheno | Sudden unexpected death in epilepsy | 1.89e-04 | 10 | 11 | 2 | HP:0033258 | |
| HumanPheno | Pes valgus | 1.95e-04 | 56 | 11 | 3 | HP:0008081 | |
| HumanPheno | Impulsivity | 1.98e-04 | 149 | 11 | 4 | HP:0100710 | |
| HumanPheno | Myopathic facies | 2.06e-04 | 57 | 11 | 3 | HP:0002058 | |
| HumanPheno | Limited neck range of motion | 2.31e-04 | 11 | 11 | 2 | HP:0000466 | |
| HumanPheno | Facial paralysis | 2.31e-04 | 11 | 11 | 2 | HP:0007209 | |
| HumanPheno | EEG with focal sharp waves | 2.77e-04 | 12 | 11 | 2 | HP:0011196 | |
| HumanPheno | Migraine with aura | 2.77e-04 | 12 | 11 | 2 | HP:0002077 | |
| HumanPheno | Epilepsia partialis continua | 2.77e-04 | 12 | 11 | 2 | HP:0012847 | |
| HumanPheno | Nuchal rigidity | 2.77e-04 | 12 | 11 | 2 | HP:0031179 | |
| HumanPheno | Generalized tonic seizure | 2.91e-04 | 64 | 11 | 3 | HP:0010818 | |
| HumanPheno | Short attention span | 3.14e-04 | 517 | 11 | 6 | HP:0000736 | |
| HumanPheno | Multifocal epileptiform discharges | 3.18e-04 | 66 | 11 | 3 | HP:0010841 | |
| HumanPheno | Generalized cerebral atrophy/hypoplasia | 3.26e-04 | 13 | 11 | 2 | HP:0007058 | |
| HumanPheno | Reduced attention regulation | 3.46e-04 | 526 | 11 | 6 | HP:5200044 | |
| HumanPheno | Cranial nerve paralysis | 3.64e-04 | 329 | 11 | 5 | HP:0006824 | |
| HumanPheno | Abnormal cranial nerve physiology | 3.80e-04 | 332 | 11 | 5 | HP:0031910 | |
| HumanPheno | Photosensitive tonic-clonic seizure | 4.38e-04 | 15 | 11 | 2 | HP:0007207 | |
| HumanPheno | Dysgenesis of the hippocampus | 5.00e-04 | 16 | 11 | 2 | HP:0025101 | |
| HumanPheno | Paroxysmal dyskinesia | 5.00e-04 | 16 | 11 | 2 | HP:0007166 | |
| HumanPheno | Abnormal oral physiology | 5.20e-04 | 355 | 11 | 5 | HP:0031815 | |
| HumanPheno | Abnormality of facial musculature | 5.62e-04 | 361 | 11 | 5 | HP:0000301 | |
| HumanPheno | Atypical absence status epilepticus | 5.67e-04 | 17 | 11 | 2 | HP:0011151 | |
| HumanPheno | Focal motor status epilepticus | 5.67e-04 | 17 | 11 | 2 | HP:0032663 | |
| HumanPheno | Non-motor seizure | 5.78e-04 | 197 | 11 | 4 | HP:0033259 | |
| HumanPheno | Dyskinesia | 5.89e-04 | 198 | 11 | 4 | HP:0100660 | |
| HumanPheno | Pes planus | 5.92e-04 | 365 | 11 | 5 | HP:0001763 | |
| HumanPheno | Gaze-evoked horizontal nystagmus | 6.37e-04 | 18 | 11 | 2 | HP:0007979 | |
| HumanPheno | Visually-induced seizure | 6.37e-04 | 18 | 11 | 2 | HP:0020216 | |
| HumanPheno | Generalized non-convulsive status epilepticus without coma | 6.37e-04 | 18 | 11 | 2 | HP:0032860 | |
| HumanPheno | Myoclonus | 6.38e-04 | 371 | 11 | 5 | HP:0001336 | |
| HumanPheno | Abnormal cranial nerve morphology | 6.71e-04 | 375 | 11 | 5 | HP:0001291 | |
| HumanPheno | Incoordination | 6.94e-04 | 1184 | 11 | 8 | HP:0002311 | |
| HumanPheno | Status epilepticus | 6.98e-04 | 207 | 11 | 4 | HP:0002133 | |
| HumanPheno | CSF lymphocytic pleiocytosis | 7.11e-04 | 19 | 11 | 2 | HP:0200149 | |
| HumanPheno | EEG with spike-wave complexes | 7.44e-04 | 88 | 11 | 3 | HP:0010850 | |
| HumanPheno | EEG with abnormally slow frequencies | 7.44e-04 | 88 | 11 | 3 | HP:0011203 | |
| HumanPheno | Non-convulsive status epilepticus without coma | 7.89e-04 | 20 | 11 | 2 | HP:0032671 | |
| HumanPheno | Rigidity | 7.92e-04 | 214 | 11 | 4 | HP:0002063 | |
| HumanPheno | Abnormal myelination | 8.69e-04 | 622 | 11 | 6 | HP:0012447 | |
| HumanPheno | Talipes valgus | 8.71e-04 | 21 | 11 | 2 | HP:0004684 | |
| HumanPheno | Abnormality of coordination | 8.98e-04 | 1227 | 11 | 8 | HP:0011443 | |
| HumanPheno | Reflex seizure | 9.57e-04 | 22 | 11 | 2 | HP:0020207 | |
| HumanPheno | Generalized-onset motor seizure | 1.01e-03 | 228 | 11 | 4 | HP:0032677 | |
| HumanPheno | Tremor | 1.01e-03 | 639 | 11 | 6 | HP:0001337 | |
| HumanPheno | Tibial torsion | 1.05e-03 | 23 | 11 | 2 | HP:0100694 | |
| HumanPheno | Vertical nystagmus | 1.05e-03 | 23 | 11 | 2 | HP:0010544 | |
| HumanPheno | Attention deficit hyperactivity disorder | 1.05e-03 | 413 | 11 | 5 | HP:0007018 | |
| HumanPheno | Pallor | 1.09e-03 | 417 | 11 | 5 | HP:0000980 | |
| HumanPheno | Mask-like facies | 1.39e-03 | 109 | 11 | 3 | HP:0000298 | |
| HumanPheno | Intellectual disability, profound | 1.39e-03 | 109 | 11 | 3 | HP:0002187 | |
| HumanPheno | Developmental regression | 1.40e-03 | 440 | 11 | 5 | HP:0002376 | |
| HumanPheno | Simple febrile seizure | 1.44e-03 | 27 | 11 | 2 | HP:0011171 | |
| HumanPheno | CSF pleocytosis | 1.44e-03 | 27 | 11 | 2 | HP:0012229 | |
| HumanPheno | Limited knee extension | 1.44e-03 | 27 | 11 | 2 | HP:0003066 | |
| HumanPheno | Status epilepticus without prominent motor symptoms | 1.44e-03 | 27 | 11 | 2 | HP:0031475 | |
| MousePheno | abnormal action potential | 3.37e-05 | 133 | 20 | 4 | MP:0005402 | |
| Domain | Na_trans_cytopl | 6.71e-08 | 6 | 29 | 3 | PF11933 | |
| Domain | Na_trans_cytopl | 6.71e-08 | 6 | 29 | 3 | IPR024583 | |
| Domain | Na_channel_asu | 4.01e-07 | 10 | 29 | 3 | IPR001696 | |
| Domain | Na_trans_assoc | 4.01e-07 | 10 | 29 | 3 | IPR010526 | |
| Domain | Na_trans_assoc | 4.01e-07 | 10 | 29 | 3 | PF06512 | |
| Domain | Channel_four-helix_dom | 9.31e-05 | 57 | 29 | 3 | IPR027359 | |
| Domain | - | 9.31e-05 | 57 | 29 | 3 | 1.20.120.350 | |
| Domain | IQ | 1.79e-04 | 71 | 29 | 3 | PF00612 | |
| Domain | IQ | 2.65e-04 | 81 | 29 | 3 | SM00015 | |
| Domain | IQ_motif_EF-hand-BS | 3.61e-04 | 90 | 29 | 3 | IPR000048 | |
| Domain | IQ | 3.98e-04 | 93 | 29 | 3 | PS50096 | |
| Domain | Ion_trans_dom | 7.21e-04 | 114 | 29 | 3 | IPR005821 | |
| Domain | Ion_trans | 7.21e-04 | 114 | 29 | 3 | PF00520 | |
| Domain | ARM-type_fold | 1.77e-03 | 339 | 29 | 4 | IPR016024 | |
| Domain | Armadillo | 2.41e-03 | 47 | 29 | 2 | IPR000225 | |
| Domain | Olfact_rcpt | 3.02e-03 | 393 | 29 | 4 | IPR000725 | |
| Domain | GPCR_Rhodpsn_7TM | 3.40e-03 | 670 | 29 | 5 | IPR017452 | |
| Domain | 7tm_1 | 3.55e-03 | 677 | 29 | 5 | PF00001 | |
| Domain | G_PROTEIN_RECEP_F1_1 | 3.74e-03 | 685 | 29 | 5 | PS00237 | |
| Domain | G_PROTEIN_RECEP_F1_2 | 3.88e-03 | 691 | 29 | 5 | PS50262 | |
| Domain | GPCR_Rhodpsn | 3.90e-03 | 692 | 29 | 5 | IPR000276 | |
| Domain | - | 4.82e-03 | 222 | 29 | 3 | 1.25.10.10 | |
| Domain | MFS | 6.34e-03 | 77 | 29 | 2 | IPR011701 | |
| Domain | MFS_1 | 6.34e-03 | 77 | 29 | 2 | PF07690 | |
| Domain | ARM-like | 8.27e-03 | 270 | 29 | 3 | IPR011989 | |
| Domain | EF-hand-dom_pair | 9.77e-03 | 287 | 29 | 3 | IPR011992 | |
| Domain | MFS_dom | 1.83e-02 | 134 | 29 | 2 | IPR020846 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 1.07e-05 | 31 | 20 | 3 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 1.18e-05 | 32 | 20 | 3 | M27455 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 2.98e-05 | 130 | 20 | 4 | M27454 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 1.69e-04 | 203 | 20 | 4 | M5485 | |
| Pathway | REACTOME_L1CAM_INTERACTIONS | 6.32e-04 | 121 | 20 | 3 | M872 | |
| Pathway | WP_DRAVET_SYNDROME | 7.07e-04 | 28 | 20 | 2 | M45519 | |
| Pubmed | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. | 1.16e-08 | 6 | 30 | 3 | 23652591 | |
| Pubmed | 4.85e-08 | 9 | 30 | 3 | 16382098 | ||
| Pubmed | 1.65e-07 | 13 | 30 | 3 | 15123669 | ||
| Pubmed | Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy. | 7.19e-07 | 2 | 30 | 2 | 37901435 | |
| Pubmed | 7.19e-07 | 2 | 30 | 2 | 33411788 | ||
| Pubmed | An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. | 7.19e-07 | 2 | 30 | 2 | 26410685 | |
| Pubmed | 7.19e-07 | 2 | 30 | 2 | 31943325 | ||
| Pubmed | Sodium channel slow inactivation interferes with open channel block. | 7.19e-07 | 2 | 30 | 2 | 27174182 | |
| Pubmed | Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics. | 7.19e-07 | 2 | 30 | 2 | 37665666 | |
| Pubmed | Genetics of migraine: an update with special attention to genetic comorbidity. | 7.19e-07 | 2 | 30 | 2 | 18451712 | |
| Pubmed | 7.19e-07 | 2 | 30 | 2 | 17881658 | ||
| Pubmed | Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance. | 2.16e-06 | 3 | 30 | 2 | 24704313 | |
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 20301562 | ||
| Pubmed | Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine. | 2.16e-06 | 3 | 30 | 2 | 18056581 | |
| Pubmed | The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels. | 2.16e-06 | 3 | 30 | 2 | 28117367 | |
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 33895391 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 17928448 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 29486580 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 38514708 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 26182346 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 32845893 | ||
| Pubmed | FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2. | 2.16e-06 | 3 | 30 | 2 | 19007941 | |
| Pubmed | De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy. | 2.16e-06 | 3 | 30 | 2 | 31054517 | |
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 28518218 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 31980564 | ||
| Pubmed | 2.16e-06 | 3 | 30 | 2 | 15302875 | ||
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 17537961 | ||
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 35031483 | ||
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 29578003 | ||
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 26747084 | ||
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 21156207 | ||
| Pubmed | Models for discovery of targeted therapy in genetic epileptic encephalopathies. | 4.31e-06 | 4 | 30 | 2 | 28742937 | |
| Pubmed | 4.31e-06 | 4 | 30 | 2 | 22260870 | ||
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | 6.18e-06 | 139 | 30 | 4 | 16985003 | |
| Pubmed | 7.18e-06 | 5 | 30 | 2 | 8812438 | ||
| Pubmed | Early development of electrical excitability in the mouse enteric nervous system. | 7.18e-06 | 5 | 30 | 2 | 22875929 | |
| Pubmed | 1.08e-05 | 6 | 30 | 2 | 16029194 | ||
| Pubmed | 1.51e-05 | 7 | 30 | 2 | 15272007 | ||
| Pubmed | Diagnostic yield of genetic testing in epileptic encephalopathy in childhood. | 1.51e-05 | 7 | 30 | 2 | 25818041 | |
| Pubmed | 2.58e-05 | 9 | 30 | 2 | 15746173 | ||
| Pubmed | Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. | 2.58e-05 | 9 | 30 | 2 | 17884088 | |
| Pubmed | Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. | 4.72e-05 | 12 | 30 | 2 | 30175250 | |
| Pubmed | Genome-wide association study identifies three new melanoma susceptibility loci. | 6.50e-05 | 14 | 30 | 2 | 21983787 | |
| Pubmed | 1.02e-04 | 105 | 30 | 3 | 30280653 | ||
| Pubmed | Different evolutionary processes shaped the mouse and human olfactory receptor gene families. | 2.01e-04 | 340 | 30 | 4 | 11875048 | |
| Pubmed | 2.01e-04 | 340 | 30 | 4 | 11802173 | ||
| Pubmed | 2.08e-04 | 343 | 30 | 4 | 32295537 | ||
| Pubmed | 2.15e-04 | 346 | 30 | 4 | 14611657 | ||
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | 3.85e-04 | 736 | 30 | 5 | 29676528 | |
| Pubmed | 3.91e-04 | 405 | 30 | 4 | 38187761 | ||
| Interaction | SCN11A interactions | 1.08e-06 | 15 | 28 | 3 | int:SCN11A | |
| Interaction | DRD4 interactions | 5.41e-06 | 25 | 28 | 3 | int:DRD4 | |
| Interaction | SCN5A interactions | 3.74e-05 | 47 | 28 | 3 | int:SCN5A | |
| Interaction | SCN4B interactions | 5.19e-05 | 8 | 28 | 2 | int:SCN4B | |
| Interaction | LPAR6 interactions | 1.13e-04 | 68 | 28 | 3 | int:LPAR6 | |
| Interaction | ADGRG2 interactions | 1.22e-04 | 12 | 28 | 2 | int:ADGRG2 | |
| Interaction | NALCN interactions | 1.68e-04 | 14 | 28 | 2 | int:NALCN | |
| Cytoband | 11q12.1 | 1.60e-04 | 161 | 30 | 3 | 11q12.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q12 | 1.47e-03 | 345 | 30 | 3 | chr11q12 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q24 | 3.14e-03 | 127 | 30 | 2 | chr2q24 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chrXq13 | 5.23e-03 | 165 | 30 | 2 | chrXq13 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 1.13e-07 | 9 | 21 | 3 | 1203 | |
| GeneFamily | Solute carriers | 1.00e-03 | 395 | 21 | 4 | 752 | |
| GeneFamily | Olfactory receptors, family 5 | 7.40e-03 | 112 | 21 | 2 | 152 | |
| ToppCell | PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass | 1.06e-04 | 137 | 30 | 3 | ed81624b9167255ce88dcf6ad7f1636376ea0525 | |
| ToppCell | PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass | 1.06e-04 | 137 | 30 | 3 | 47859aa25f32367461c1ec75ed9060bee430c6b7 | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.61e-04 | 158 | 30 | 3 | f296ca24fdedc33f1d24b79e7660763114ce7fa3 | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.61e-04 | 158 | 30 | 3 | 8c7108f2c40d97a317762ba0b8eca76542b2ebaf | |
| ToppCell | 390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 1.67e-04 | 160 | 30 | 3 | 636127753e3a22831f39d4c8170df40901e4329d | |
| ToppCell | 390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 1.67e-04 | 160 | 30 | 3 | cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63 | |
| ToppCell | Healthy_donor-CD8+_T_naive|World / disease group, cell group and cell class (v2) | 1.70e-04 | 161 | 30 | 3 | 8a61395af33132783a0a37956c6f821aba5d3b1e | |
| ToppCell | Adult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor | 1.96e-04 | 169 | 30 | 3 | e1f0298236e4a1c59077c14f0dd29a78fac12648 | |
| ToppCell | TCGA-Brain|World / Sample_Type by Project: Shred V9 | 2.00e-04 | 170 | 30 | 3 | f78e360a6a44d599ec0d207cba4704e50aa314f8 | |
| ToppCell | lymphoid-B_cell-pro-B|B_cell / Lineage, cell class and subclass | 2.07e-04 | 172 | 30 | 3 | da1e2e54f442f5c2032c857c4812e9060f2053cd | |
| ToppCell | 5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.10e-04 | 173 | 30 | 3 | b335ca2a247156eba821943b2b9fc9922230b409 | |
| ToppCell | wk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 2.17e-04 | 175 | 30 | 3 | a84965d28438a4228d841b357c2cd75cf4b59a63 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.25e-04 | 177 | 30 | 3 | d05497d2c80a66ec6a4e1733fea3a5534877a6a7 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.44e-04 | 182 | 30 | 3 | ecb5624c9074cc6449fad961df54c926c2681d54 | |
| ToppCell | LPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.52e-04 | 184 | 30 | 3 | c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc | |
| ToppCell | COVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass | 2.60e-04 | 186 | 30 | 3 | 63a5cdd3f60681762a218be32db84be8f29b88fd | |
| ToppCell | COVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass | 2.60e-04 | 186 | 30 | 3 | 39457a7b43537f2c3e221f9375c95d4515424d7d | |
| ToppCell | Control-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.64e-04 | 187 | 30 | 3 | ea9d34bcd3bd1f36745846309ede349773de501a | |
| ToppCell | LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.64e-04 | 187 | 30 | 3 | f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1 | |
| ToppCell | LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.68e-04 | 188 | 30 | 3 | 73f6ec915934154f435a376cb274b058ff7c5f35 | |
| ToppCell | Control-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.72e-04 | 189 | 30 | 3 | 5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1 | |
| ToppCell | LPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.77e-04 | 190 | 30 | 3 | 474cbbab8f3b0a6881fa6c92edb78e43999f9ab0 | |
| ToppCell | LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.77e-04 | 190 | 30 | 3 | a3c6eec6df052105ab78b7e3c78f94218d5912eb | |
| ToppCell | LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.77e-04 | 190 | 30 | 3 | 106ea0bb7b99c697ffc5443d72343df2484250c7 | |
| ToppCell | LPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.81e-04 | 191 | 30 | 3 | a7b18bcf27c38ad2353c239ecb309c80f3ef3359 | |
| ToppCell | PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 2.85e-04 | 192 | 30 | 3 | d0649410cf5eacdb0c1dce70e37c7473ef5fddfa | |
| ToppCell | LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.85e-04 | 192 | 30 | 3 | c618ede75dce3988c87a5b8f98d8e94e1dd66efd | |
| ToppCell | Control-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.90e-04 | 193 | 30 | 3 | aff0649c73c634bc6ff0dc7759b4693a9236bf05 | |
| ToppCell | Control-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.90e-04 | 193 | 30 | 3 | c5f9fe03e64c211d4bcd4959e5b32f14841e336a | |
| ToppCell | LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.90e-04 | 193 | 30 | 3 | a3636c35ed25aabe2f1aba016c9fe125327bbfaf | |
| ToppCell | 5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.90e-04 | 193 | 30 | 3 | cdc44bf6f5436eb8a2d4720fe011dcb85ccecf87 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.90e-04 | 193 | 30 | 3 | 66af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4 | |
| ToppCell | LPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.94e-04 | 194 | 30 | 3 | 1d39d968730a7e85b6161c1c8a6bd38afe9bcad7 | |
| ToppCell | LPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.94e-04 | 194 | 30 | 3 | 43f92b0533e26633dc94cce554045d641ef8fd76 | |
| ToppCell | Tracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 3.12e-04 | 198 | 30 | 3 | c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc | |
| ToppCell | Tracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 3.12e-04 | 198 | 30 | 3 | 55f013e9e6587d9ece59751fa131b1d22d6cceea | |
| ToppCell | 3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 3.17e-04 | 199 | 30 | 3 | 8d13a9ea87f685b5a34b84c4571db6be753cf2d9 | |
| Drug | thephorin | 1.68e-06 | 2 | 30 | 2 | CID000011290 | |
| Drug | ethacizine | 1.01e-05 | 4 | 30 | 2 | CID000107841 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 9.14e-08 | 10 | 28 | 3 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 9.14e-08 | 10 | 28 | 3 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 1.67e-07 | 12 | 28 | 3 | DOID:0060170 (implicated_via_orthology) | |
| Disease | Early Infantile Epileptic Encephalopathy 6 | 8.68e-07 | 2 | 28 | 2 | C4551549 | |
| Disease | B Virus Infection | 2.60e-06 | 3 | 28 | 2 | C0037140 | |
| Disease | Familial or sporadic hemiplegic migraine | 2.60e-06 | 3 | 28 | 2 | cv:CN295307 | |
| Disease | Postherpetic neuralgia | 2.60e-06 | 3 | 28 | 2 | C0032768 | |
| Disease | Herpesviridae Infections | 2.60e-06 | 3 | 28 | 2 | C0019372 | |
| Disease | Familial hemiplegic migraine | 2.60e-06 | 3 | 28 | 2 | cv:C0338484 | |
| Disease | Cerebral Small Vessel Diseases | 8.67e-06 | 5 | 28 | 2 | C2733158 | |
| Disease | Familial benign neonatal epilepsy | 1.30e-05 | 6 | 28 | 2 | C0220669 | |
| Disease | epilepsy (implicated_via_orthology) | 1.66e-05 | 163 | 28 | 4 | DOID:1826 (implicated_via_orthology) | |
| Disease | Early Childhood Epilepsy, Myoclonic | 2.42e-05 | 8 | 28 | 2 | C0393695 | |
| Disease | Idiopathic Myoclonic Epilepsy | 2.42e-05 | 8 | 28 | 2 | C0338478 | |
| Disease | Symptomatic Myoclonic Epilepsy | 2.42e-05 | 8 | 28 | 2 | C0338479 | |
| Disease | Myoclonic Encephalopathy | 2.42e-05 | 8 | 28 | 2 | C0438414 | |
| Disease | Benign Infantile Myoclonic Epilepsy | 2.42e-05 | 8 | 28 | 2 | C0751120 | |
| Disease | Myoclonic Absence Epilepsy | 2.42e-05 | 8 | 28 | 2 | C0393703 | |
| Disease | Pruritus | 2.42e-05 | 8 | 28 | 2 | C0033774 | |
| Disease | Myoclonic Epilepsy | 3.11e-05 | 9 | 28 | 2 | C0014550 | |
| Disease | Generalized Epilepsy with Febrile Seizures Plus | 3.11e-05 | 9 | 28 | 2 | C3502809 | |
| Disease | Epilepsy, Myoclonic, Infantile | 3.89e-05 | 10 | 28 | 2 | C0917800 | |
| Disease | Myoclonic Astatic Epilepsy | 4.75e-05 | 11 | 28 | 2 | C0393702 | |
| Disease | Infantile Severe Myoclonic Epilepsy | 6.73e-05 | 13 | 28 | 2 | C0751122 | |
| Disease | Epilepsy | 1.50e-04 | 109 | 28 | 3 | C0014544 | |
| Disease | anxiety disorder (implicated_via_orthology) | 1.98e-04 | 22 | 28 | 2 | DOID:2030 (implicated_via_orthology) | |
| Disease | Mental Retardation, Psychosocial | 3.07e-04 | 139 | 28 | 3 | C0025363 | |
| Disease | Profound Mental Retardation | 3.07e-04 | 139 | 28 | 3 | C0020796 | |
| Disease | Mental deficiency | 3.07e-04 | 139 | 28 | 3 | C0917816 | |
| Disease | Inherited neuropathies | 6.62e-04 | 40 | 28 | 2 | C0598589 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| YMLLVGNIIMMPDAQ | 211 | Q9NX77 | |
| MMGDSMVKINGIYLT | 166 | Q8NEN0 | |
| MLGQFLQEVSIMAVM | 656 | Q9HC96 | |
| PMQASQAIGYLLGMM | 441 | P36021 | |
| FMAMIANGVMIFLIN | 36 | Q8NHC8 | |
| VVYIITMVGNIGMMV | 31 | Q8NGP4 | |
| YMANMVGNLGMIVLI | 41 | Q8NGF4 | |
| YQLAARMGTKMMGGL | 2521 | Q13315 | |
| LISMAYGQIGMIQAL | 846 | P50993 | |
| LGICYGMQMMNKVFG | 101 | P49915 | |
| YGVQAGMKMIEQMLK | 41 | Q8NFQ6 | |
| MWGLYEGQQPMLVIM | 71 | Q9HB55 | |
| NGLTPQKMEVMMYGL | 276 | P0DN25 | |
| VGAVVMPMNILYLLM | 76 | P35367 | |
| ILTLGVMMLVGMALY | 106 | Q9UMX9 | |
| VMMLVGMALYLNGAT | 111 | Q9UMX9 | |
| SIFVNIYLMMQMTAG | 551 | Q8WY07 | |
| MLMLRMIMSGNYQFG | 236 | Q16816 | |
| KEQRQMNGMYTGLMG | 176 | Q86VY9 | |
| TMVYNGMNMEAIHVL | 331 | Q9NVN3 | |
| IVYMMVMVIGNLVVL | 946 | Q15858 | |
| MVLMQMGQPALLYLV | 491 | Q8IUH8 | |
| FLMIYVISVMGNLGM | 31 | Q8NH51 | |
| VFMMVMVIGNLVVLN | 971 | P35498 | |
| YIKVVMQNGRMMGAV | 446 | Q8WU10 | |
| LDIQMIMIMNGTLYI | 56 | Q9H2E6 | |
| MGAEMQPYVQMVLNN | 736 | O14787 | |
| VFMMVMVIGNLVVLN | 956 | Q9UQD0 | |
| TGGMMQLLMNNPYLA | 426 | Q8IYU4 | |
| VIASAIMMQNFGLMI | 251 | Q8NEW0 | |
| VLNMLMMTAVNGVAV | 1061 | O60290 | |
| GVMYLKLVLGQMVQA | 66 | Q6AWC8 |