Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled photoreceptor activity

OPN1MW OPN1MW2 OPN1MW3

3.50e-0515873GO:0008020
GeneOntologyMolecularFunctionphotoreceptor activity

OPN1MW OPN1MW2 OPN1MW3

5.20e-0517873GO:0009881
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 ITPR1 CNGA4

3.97e-0433873GO:0005217
GeneOntologyMolecularFunction5'-deoxyribose-5-phosphate lyase activity

XRCC5 POLQ

5.17e-048872GO:0051575
GeneOntologyCellularComponentGolgi-associated vesicle

COPB1 OCRL SPPL2A CNGA4 UNC13A RAB27B

1.19e-05114936GO:0005798
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN1MW OPN1MW2 OPN1MW3

2.06e-0426933GO:0097381
GeneOntologyCellularComponentplatelet dense granule membrane

ITPR1 RAB27B

2.90e-046932GO:0031088
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

4.31e-074903PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

4.31e-074903IPR032754
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

4.31e-074903IPR029423
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

4.31e-074903PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

4.31e-074903IPR015753
DomainARM-type_fold

DOCK2 COPB1 APOB TRIP12 ITPR1 AP3B2 PDS5A STAG3L3 NUP188 EIF4G3

5.37e-063399010IPR016024
DomainDistrobrevin

DTNA DTNB

2.30e-052902IPR017432
DomainOpsin_red/grn

OPN1MW OPN1MW3

6.87e-053902IPR000378
DomainRIH_assoc

RYR1 ITPR1

3.40e-046902PF08454
DomainRIH_assoc-dom

RYR1 ITPR1

3.40e-046902IPR013662
DomainRIH_dom

RYR1 ITPR1

3.40e-046902IPR000699
DomainIns145_P3_rcpt

RYR1 ITPR1

3.40e-046902IPR014821
DomainRyanodine_recept-rel

RYR1 ITPR1

3.40e-046902IPR015925
Domain-

RYR1 ITPR1

3.40e-0469021.25.10.30
DomainEF-hand_dom_typ1

DTNA DTNB

3.40e-046902IPR015153
DomainEF-hand_dom_typ2

DTNA DTNB

3.40e-046902IPR015154
DomainRYDR_ITPR

RYR1 ITPR1

3.40e-046902PF01365
DomainEF-hand_2

DTNA DTNB

3.40e-046902PF09068
DomainEF-hand_3

DTNA DTNB

3.40e-046902PF09069
DomainIns145_P3_rec

RYR1 ITPR1

3.40e-046902PF08709
DomainMIR

RYR1 ITPR1

1.01e-0310902PS50919
DomainMIR

RYR1 ITPR1

1.01e-0310902PF02815
DomainMIR

RYR1 ITPR1

1.01e-0310902SM00472
DomainOPSIN

OPN1MW OPN1MW3

1.01e-0310902PS00238
DomainMIR_motif

RYR1 ITPR1

1.01e-0310902IPR016093
DomainOpsin

OPN1MW OPN1MW3

1.23e-0311902IPR001760
DomainARM-like

DOCK2 COPB1 TRIP12 AP3B2 PDS5A STAG3L3

1.95e-03270906IPR011989
DomainIon_trans_dom

KCNH8 RYR1 ITPR1 CNGA4

2.25e-03114904IPR005821
DomainIon_trans

KCNH8 RYR1 ITPR1 CNGA4

2.25e-03114904PF00520
DomainClathrin/coatomer_adapt-like_N

COPB1 AP3B2

2.31e-0315902IPR002553
DomainAdaptin_N

COPB1 AP3B2

2.31e-0315902PF01602
DomainZZ

DTNA DTNB

3.34e-0318902PF00569
DomainZF_ZZ_2

DTNA DTNB

3.34e-0318902PS50135
DomainZF_ZZ_1

DTNA DTNB

3.34e-0318902PS01357
DomainZnf_ZZ

DTNA DTNB

3.72e-0319902IPR000433
DomainZnF_ZZ

DTNA DTNB

3.72e-0319902SM00291
Pubmed

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

OPN1MW OPN1MW2 OPN1MW3

8.40e-08497329386880
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

8.40e-08497322419166
Pubmed

Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

OPN1MW OPN1MW2 OPN1MW3

2.09e-0759732937147
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SART3 POLR1A WRNIP1 MED1 PRC1 XRCC5 TRIP12 ITPR1 TRIM28 NUP188

4.48e-07440971034244565
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

COPB1 CCDC146 APOB OCRL TRIP12 FAM83B NF2 CCT5 PKLR PDS5A EIF4G3 FAM135A

1.79e-06777971235844135
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SART3 POLR1A KIF27 COPB1 APOB PRC1 XRCC5 MAST2 FANCD2 CYFIP1 PMPCA CCT5 TRIM28 PDS5A NUP188 PHIP

2.01e-061425971630948266
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

2.49e-061097323064749
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

COPB1 DTNA OCRL XRCC5 FAM83B CYFIP1 CCT5 TRIM28 PDS5A EIF4G3 FAM135A

4.69e-06708971139231216
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

DOCK2 SART3 COPB1 XRCC5 TRIP12 ITPR1 NUP188 PHIP

5.22e-0634097829478914
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

SART3 MED1 XRCC5 TRIP12 CCT5 TRIM28

5.22e-0615697637108203
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SART3 KCNH8 MAST2 TRIP12 RYR1 NF2 CCT5 KIAA1217 EIF4G3 RAB27B NIN

6.42e-06732971134732716
Pubmed

Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues.

OPN1MW2 OPN1MW3 CCDC136

7.49e-061497337033230
Pubmed

Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.

OPN1MW OPN1MW2

7.70e-06297228402104
Pubmed

NF2 regulates IP3R-mediated Ca2+ signal and apoptosis in meningiomas.

ITPR1 NF2

7.70e-06297238953724
Pubmed

Defective colour vision associated with a missense mutation in the human green visual pigment gene.

OPN1MW OPN1MW2

7.70e-0629721302020
Pubmed

Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.

OPN1MW OPN1MW2

7.70e-06297210319869
Pubmed

Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP(3) type 1 receptor.

RYR1 ITPR1

7.70e-06297212654335
Pubmed

Muscular dystrophies and the dystrophin-glycoprotein complex.

DTNA DTNB

7.70e-0629729146999
Pubmed

Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin.

COPB1 OCRL

7.70e-0629721840503
Pubmed

Expression and reconstitution of the bioluminescent Ca(2+) reporter aequorin in human embryonic stem cells, and exploration of the presence of functional IP3 and ryanodine receptors during the early stages of their differentiation into cardiomyocytes.

RYR1 ITPR1

7.70e-06297227430888
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SART3 POLR1A COPB1 XRCC5 TRIP12 CCT5 PDS5A NUP188 EIF4G3 PHIP

1.48e-05653971022586326
Pubmed

Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome.

OPN1MW2 OPN1MW3 TRIM28

1.66e-051897332994318
Pubmed

Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.

DTNA DTNB

2.31e-05397211316798
Pubmed

Molecular determinants of human red/green color discrimination.

OPN1MW OPN1MW2

2.31e-0539728185948
Pubmed

X-linked cone dystrophy caused by mutation of the red and green cone opsins.

OPN1MW OPN1MW2

2.31e-05397220579627
Pubmed

Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

OPN1MW2 OPN1MW3

2.31e-05397238410159
Pubmed

Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.

OPN1MW2 OPN1MW3

2.31e-05397223350963
Pubmed

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.

OPN1MW2 OPN1MW3

2.31e-05397220471354
Pubmed

Multiple hypothalamic cell populations encoding distinct visual information.

OPN1MW2 OPN1MW3

2.31e-05397221224225
Pubmed

Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.

OPN1MW2 OPN1MW3

2.31e-05397236216501
Pubmed

Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).

OPN1MW2 OPN1MW3

2.31e-05397210567724
Pubmed

Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin.

DTNA DTNB

2.31e-05397216540561
Pubmed

Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.

OPN1MW2 OPN1MW3

2.31e-05397234111401
Pubmed

Molecular basis of dystrobrevin interaction with kinesin heavy chain: structural determinants of their binding.

DTNA DTNB

2.31e-05397216288919
Pubmed

Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.

OPN1MW2 OPN1MW3

2.31e-05397214500905
Pubmed

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.

FANCD2 POLQ

2.31e-05397225642963
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

RYR1 ITPR1

2.31e-05397223223241
Pubmed

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.

OPN1MW2 OPN1MW3

2.31e-05397228751656
Pubmed

beta-dystrobrevin, a member of the dystrophin-related protein family.

DTNA DTNB

2.31e-0539729419360
Pubmed

Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.

OPN1MW2 OPN1MW3

2.31e-05397231469404
Pubmed

The molecular genetics and evolution of red and green color vision in vertebrates.

OPN1MW2 OPN1MW3

2.31e-05397211545071
Pubmed

Mechanisms of spectral tuning in the mouse green cone pigment.

OPN1MW2 OPN1MW3

2.31e-0539729238068
Pubmed

Emergence of novel color vision in mice engineered to express a human cone photopigment.

OPN1MW2 OPN1MW3

2.31e-05397217379811
Pubmed

Intracellular calcium release channel expression during embryogenesis.

RYR1 ITPR1

2.31e-0539729986730
Pubmed

Co-expression of murine opsins facilitates identifying the site of cone adaptation.

OPN1MW2 OPN1MW3

2.31e-05397212511072
Pubmed

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.

OPN1MW2 OPN1MW3

2.31e-0539727958444
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

SART3 POLR1A DTNA WRNIP1 TRIP12 MELK PMPCA NF2 PKLR NUP188 EIF4G3 NIN

2.37e-051005971219615732
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DTNA OCRL FAM83B CYFIP1 NF2 KIAA1217 FAM135A RAB27B

2.44e-0542197836976175
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

SART3 POLR1A COPB1 PRC1 XRCC5 CKM CYFIP1 CCT5 KIAA1217 AP3B2 EIF4G3

2.48e-05847971135235311
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SART3 POLR1A COPB1 TRIP12 FANCD2 CYFIP1 TRIM28 PDS5A NUP188 EIF4G3

2.80e-05704971029955894
Pubmed

Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line.

OPN1MW2 OPN1MW3 CCDC136

3.58e-052397326965927
Pubmed

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.

OPN1MW2 OPN1MW3

4.60e-05497231461375
Pubmed

Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.

OPN1MW2 OPN1MW3

4.60e-0549728088841
Pubmed

Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.

OPN1MW2 OPN1MW3

4.60e-05497228103478
Pubmed

Molecular biology of the visual pigments.

OPN1MW OPN1MW2

4.60e-0549723303660
Pubmed

Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.

OPN1MW2 OPN1MW3

4.60e-05497231846668
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 ITPR1

4.60e-05497223413940
Pubmed

Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly.

CCT5 PDCL

4.60e-05497215889144
Pubmed

A targeted next-generation sequencing panel reveals novel mutations in Japanese patients with primary ciliary dyskinesia.

DNAI1 CCDC40

4.60e-05497228939216
Pubmed

Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.

OPN1MW2 OPN1MW3

4.60e-05497226438865
Pubmed

DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes.

DTNA DTNB

4.60e-05497214623885
Pubmed

Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.

OPN1MW2 OPN1MW3

4.60e-05497217249565
Pubmed

Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.

OPN1MW2 OPN1MW3

4.60e-05497238060327
Pubmed

Contribution of M-opsin-based color vision to refractive development in mice.

OPN1MW2 OPN1MW3

4.60e-05497234126082
Pubmed

Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.

OPN1MW2 OPN1MW3

4.60e-05497216567464
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 ITPR1

4.60e-0549729607712
Pubmed

Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS.

DTNA DTNB

4.60e-05497216807372
Pubmed

S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.

OPN1MW2 OPN1MW3

4.60e-05497224801621
Pubmed

Melanopsin Contributions to the Representation of Images in the Early Visual System.

OPN1MW2 OPN1MW3

4.60e-05497228528909
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR1 ITPR1

4.60e-05497219120137
Pubmed

Melanopsin-driven light adaptation in mouse vision.

OPN1MW2 OPN1MW3

4.60e-05497225308073
Pubmed

Genomic organization and refined mapping of the mouse beta-dystrobrevin gene.

DTNB APOB

4.60e-0549729799833
Pubmed

DNA segments mapped by reciprocal use of microsatellite primers between mouse and rat.

OPN1MW2 OPN1MW3 PKLR

4.63e-05259738268655
Pubmed

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.

SART3 CYFIP1 UBE2V2 TRIM28 PDS5A

5.57e-0514597528846114
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SART3 COPB1 WRNIP1 XRCC5 CYFIP1 CCT5 TRIM28 PDS5A NUP188

7.57e-0563897933239621
Pubmed

Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.

OPN1MW2 OPN1MW3

7.66e-05597236631163
Pubmed

Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.

OPN1MW2 OPN1MW3

7.66e-05597226818794
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAI1 CCDC40

7.66e-05597222499950
Pubmed

A common integration locus in type B retrovirus-induced thymic lymphomas.

OPN1MW2 OPN1MW3

7.66e-0559721333116
Pubmed

A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.

OPN1MW2 OPN1MW3

7.66e-05597222090509
Pubmed

Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.

OPN1MW2 OPN1MW3

7.66e-05597210723722
Pubmed

Intracellular calcium-release channels: regulators of cell life and death.

RYR1 ITPR1

7.66e-0559729124414
Pubmed

Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.

OPN1MW2 OPN1MW3

7.66e-05597227033727
Pubmed

Mutations in DEPDC5 cause familial focal epilepsy with variable foci.

GAD1 DEPDC5

7.66e-05597223542697
Pubmed

BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.

XRCC5 FANCD2

7.66e-05597222445484
Pubmed

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding.

CCT5 PDCL

7.66e-05597224375412
Pubmed

Melanopsin-based brightness discrimination in mice and humans.

OPN1MW2 OPN1MW3

7.66e-05597222633808
Pubmed

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

OPN1MW2 OPN1MW3

7.66e-05597211055434
Pubmed

STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion.

STAG3L2 STAG3L3

7.66e-05597210698974
Pubmed

Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.

OPN1MW2 OPN1MW3

7.66e-05597224058409
Pubmed

Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.

OPN1MW2 OPN1MW3

7.66e-05597234099749
Pubmed

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.

CMTR1 OPN1MW2 OPN1MW3 CCDC136

8.02e-058197416110338
Pubmed

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance.

OPN1MW2 CCNG1 OPN1MW3

8.08e-053097337048108
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MAGEA1 SART3 POLR1A COPB1 OCRL XRCC5 TRIP12 MELK CYFIP1 CCT5 TRIM28 PDS5A PHIP

9.89e-051353971329467282
Pubmed

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.

SART3 CCT5 TRIM28 PDS5A

1.06e-048797424169447
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

COPB1 ALDH1L1 XRCC5 CCDC7 CKM CCT5

1.11e-0426997630442662
Pubmed

Myospryn is a novel binding partner for dysbindin in muscle.

DTNA DTNB

1.15e-04697214688250
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 ITPR1

1.15e-04697223463619
Pubmed

Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome.

TRBC2 TRBC1

1.15e-04697230863395
Pubmed

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

OPN1MW2 OPN1MW3

1.15e-04697223288843
InteractionKCNA3 interactions

CMTR1 COPB1 DTNA OCRL XRCC5 RYR1 FAM83B CYFIP1 NF2 CCT5 TRIM28 AP3B2 PDS5A EIF4G3 POLQ FAM135A

1.87e-068719216int:KCNA3
GeneFamilyOpsin receptors

OPN1MW OPN1MW2 OPN1MW3

4.56e-0611563215
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DTNA DTNB

1.40e-031856291
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPM1E CKM DNAI1 PTPRN AP3B2 UNC13A

2.20e-06175966182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early|lymph-node_spleen / Manually curated celltypes from each tissue

GAD1 TRIM58 EMID1 PRC1 MELK PKLR

3.23e-0618796661d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 GMFG MELK FANCD2 TRBC2 POLQ

3.54e-06190966b65383e256b04122500b742caeed0b807793851e
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 GMFG MELK FANCD2 TRBC2 POLQ

3.54e-0619096689095d3e023269d89c82e3a73550f869e3f34201
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EQTN ARHGEF38 MELK CCKAR

6.57e-0656964ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EQTN ARHGEF38 MELK CCKAR

6.57e-065696420a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(Neuron.Gad1Gad2.Sst-Crh)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TRIM58 EQTN OPN1MW PKLR

1.19e-0565964d77193259479d0c1667804682dc5b605ebf7119b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(Neuron.Gad1Gad2.Sst-Crh)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TRIM58 EQTN OPN1MW PKLR

1.19e-0565964443827bb2c469046026ca9b4c52b22bef0681dff
ToppCellControl-Epithelial_airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 FAM83B DNAI1 CHP2 RAB27B

2.37e-0515896535aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

GAD1 TRIM58 PRC1 MELK PKLR

2.44e-051599650fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

KIF27 CCDC146 FHAD1 DNAI1 CCDC40

3.09e-0516796526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 PRC1 MELK FANCD2 CKM

3.27e-05169965822e5b6c1e55e196e6d2a38bf183fd220c45703e
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRERF1 GMFG RYR1 TRBC2 TRBC1

3.36e-05170965059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTNB EMID1 PRC1 MELK POLQ

3.46e-051719651eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF27 CCDC146 CCKAR FHAD1 PTPRN

3.46e-051719654f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PRC1 MELK ADCY7 POLQ

3.46e-0517196555c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 GMFG ANKRD36B PDCL TRBC2

3.55e-05172965eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

TRERF1 DOCK2 GMFG TRBC1 RAB27B

3.65e-05173965212f013ff761cbab24a537071739867c08c402a4
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 POLR1A GMFG TRBC2 TRBC1

3.65e-051739657186add017271382ecafbff8ee87afb45fbfc745
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAD1 KCNH8 PTPRN AP3B2 CCDC136

3.86e-051759658362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAD1 KCNH8 PTPRN AP3B2 CCDC136

3.86e-051759658b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CCDC146 FHAD1 DNAI1 CCDC40

3.97e-05176965ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FHAD1 AP3B2 POLQ FAM135A UNC13A

4.07e-051779658abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC146 FHAD1 DNAI1 PKLR CCDC40

4.30e-05179965d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC146 FHAD1 DNAI1 PKLR CCDC40

4.30e-051799658a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 LRRC37A3 DTNA PPM1E NIN

4.41e-05180965c72f15763ba707189e29c85db533557f01c7fdb1
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

TRERF1 DOCK2 GMFG TRBC1 RAB27B

4.53e-0518196581fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 PRC1 MELK FANCD2 CKM

4.65e-051829650370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 PPM1E ALDH1L1 FAM83B ITPR1

5.29e-05187965b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIRE2 KCNH8 DTNA EMID1 ASPA

5.29e-0518796516e55d802fc4e71878305e61ad03806aabd59537
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PRC1 MELK RYR1 POLQ

5.29e-0518796573931a5ea73799095daff100b5f18853c57c74dc
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM58 RNF10 ANKRD36 UNC13A

5.34e-0595964756d76830b8e7e8903b2bc7a39a38880be684297
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF27 CCDC146 CCKAR FHAD1 CCDC40

5.56e-0518996538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellE18.5-Epithelial-Epithelial_Airway|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF27 CCDC146 CCKAR FHAD1 CCDC40

5.70e-051909655c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 PPM1E ARHGEF38 ALDH1L1 ITPR1

5.70e-05190965cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRC1 MELK FANCD2 TRBC2 POLQ

6.14e-0519396581e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

KIF27 CCDC146 ARHGEF38 FHAD1 DNAI1

6.45e-0519596560067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GMFG PRC1 MELK TRBC2 POLQ

6.93e-05198965d484ac79d6cd29f1d9c192d126c2099f737d5320
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

PRC1 MELK FANCD2 CCT5 POLQ

6.93e-05198965880f9817f5145f10f29fc05c5866090433532fe2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GMFG PRC1 MELK TRBC2 POLQ

6.93e-05198965ac0be1666456cfa8d68588b187d65008e6d5c0e2
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-Treg|Influenza_Severe / Disease, condition lineage and cell class

KIF27 FAM209A ANKRD36 TRBC2 CCDC136

6.93e-05198965e377fa0215f338f86ee2903ce3fa57cea805a630
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CCDC146 TRIP12 ANKRD36B FHAD1 ANKRD36

7.10e-0519996561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellTransverse-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

OCRL PRC1 MELK FANCD2 POLQ

7.10e-051999657cfe9b2538ea008d67343f3e8bfec3bf81200de6
ToppCellBiopsy_Other_PF-Immune-Proliferating_T_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

PRC1 MELK TRBC2 TRBC1 POLQ

7.10e-051999651d55d06e658939b78ea046553757821381eaa026
ToppCellcellseq2-Immune|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK2 GMFG ADA2 TRBC2 TRBC1

7.10e-05199965631f29931d102ea308088809a05281588c9c9e3d
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KIF27 CCDC146 FAM83B FHAD1 DNAI1

7.10e-0519996515f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellBiopsy_IPF-Immune-Proliferating_T_cells|Biopsy_IPF / Sample group, Lineage and Cell type

PRC1 MELK TRBC2 TRBC1 POLQ

7.27e-05200965c43d1a83b2a8ad060f3d80c9438da8b7a5e307fb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

KIF27 CCDC146 FHAD1 DNAI1 CCDC40

7.27e-05200965177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRERF1 GAD1 KCNH8 RYR1

1.37e-04121964b2d571f571133c281d72584fe925cebbd2317829
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FANCD2 FHAD1 TRBC2 TRBC1

1.41e-0412296437612ad087d9c11d4a3466244ab36224de31930b
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Ajap1_(Entorhinal_cortex)|Hippocampus / BrainAtlas - Mouse McCarroll V32

EQTN OPN1MW TRBC2

1.62e-04499630b3e9c8f166be5d6aab318da4b87176427637877
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D231|Adult / Lineage, Cell type, age group and donor

ANKRD30B FAM83B RERGL KIAA1217

1.91e-041329648d30b71776f5f6da55dc78e0c5cb27be460004e3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Tshz2_(Deep_layer_pyramidal_cells--layer_5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

OPN1MW CCDC7 PHEX

2.53e-0457963d80eb5ade3c90344b67811e7f313c7d0720715f0
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

ANKRD36 TRBC2 TRBC1 UNC13A

2.73e-0414596429422c908d58081e6a748e362a7ac41bf001444c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2|TCGA-Pancreas / Sample_Type by Project: Shred V9

LRRC37A3 DNAI1 AP3B2 UNC13A

2.80e-04146964bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

LRRC37A3 DNAI1 AP3B2 UNC13A

2.80e-0414696472c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC146 ARHGEF38 FHAD1 DNAI1

2.95e-04148964d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC146 ARHGEF38 FHAD1 DNAI1

2.95e-04148964c8e93b87212f55774223caa385859c566fa1981f
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 GMFG DNAI1 RERGL

3.03e-04149964a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 EMID1 TRBC2 UNC13A

3.11e-041509641270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 EMID1 TRBC2 UNC13A

3.11e-04150964156118ce1d69522624196410cba18b8354cd0bb4
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FANCD2 FHAD1 TRBC2 TRBC1

3.11e-041509649d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCellHealthy_donor-RBC|World / disease group, cell group and cell class (v2)

KCNH8 TRIM58 CCDC146 RNF10

3.11e-041509641e1a497ec4b048f7e9cc12dd5dd9aba7fedca9e1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 CCDC146 ADCY7 UNC13A

3.35e-041539644eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 CCDC146 ADCY7 UNC13A

3.35e-0415396426b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 CCDC146 ADCY7 UNC13A

3.35e-041539640f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCellRV-17._Lymphocyte|RV / Chamber and Cluster_Paper

DOCK2 GMFG TRBC1 RAB27B

3.35e-04153964e1ea621184014415870e00d511386b8cc3e0833b
ToppCellRV-17._Lymphocyte|World / Chamber and Cluster_Paper

DOCK2 GMFG TRBC1 RAB27B

3.52e-04155964189276a3b400b2202e6681e23732e6452bfe704e
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 CKM TRBC2 TRBC1

3.52e-041559644ae91bc7dbb9f713a1f110c17834b1d89f1b28db
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EMID1 PRC1 MELK POLQ

3.52e-04155964969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 CKM TRBC2 TRBC1

3.52e-04155964fdcc8a475156329b3594d5ed22ba03538305327c
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 CKM TRBC2 TRBC1

3.52e-041559641fb49b48e34e740118908951e079ea2a9994ae4f
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 EMID1 PKLR RAB27B

3.69e-04157964ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCellHealthy/Control-RBC|Healthy/Control / Disease group and Cell class

KCNH8 TRIM58 AMN1 RNF10

3.78e-041589641fec4f9affdbfba2e281183b717d4d357d474400
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYFIP1 TBC1D22A CHP2 UNC13A

3.78e-041589649a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYFIP1 TBC1D22A CHP2 UNC13A

3.78e-041589642438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNH8 PTPRN AP3B2 UNC13A

3.87e-041599647747cef94c55144fddcd024a7495318357f1351b
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|368C / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A2 TRBC2 TRBC1 CCDC136

3.87e-041599647065062fce248e0458932a22dfcc25a5b5a70cbd
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 TRBC2 TRBC1 UNC13A

3.97e-04160964b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC146 EMID1 CCDC136 RAB27B

3.97e-04160964398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 TRBC2 TRBC1 UNC13A

3.97e-041609649caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCellHealthy/Control-RBC|World / Disease group and Cell class

KCNH8 TRIM58 AMN1 RNF10

3.97e-04160964f10871238e7bdf3e1f65a17070000477196e50fe
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC146 EMID1 CCDC136 RAB27B

3.97e-0416096412aaab0291035f578e2433efd169ae72f393a5a5
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 TRBC2 TRBC1 UNC13A

3.97e-04160964229841be7b984a00a301cd5d88c11226a90d8a88
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 TRBC2 TRBC1 UNC13A

3.97e-0416096499c9ae2041445539fada842e1af01368669bfca0
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ANKRD36C ITPR1 ANKRD36B LRRC37A

4.16e-04162964b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DTNA MAST2 MELK CCDC136

4.26e-04163964ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRC1 MELK FANCD2 POLQ

4.26e-041639645285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A2 VSTM4 LRRC37A CCDC136

4.36e-041649641aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD30B PRC1 MELK POLQ

4.36e-041649641642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRC1 MELK CKM PKLR

4.36e-04164964fb18b863152fb3109e2224c791c84c6371680a4e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD30B PRC1 MELK POLQ

4.36e-0416496425758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH8 PTPRN AP3B2 UNC13A

4.36e-04164964be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GMFG TRBC2 TRBC1 UNC13A

4.46e-04165964567c9f8fe29b5d34c2e39d9a17db54eba51ee559
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GMFG TRBC2 TRBC1 UNC13A

4.46e-04165964cdc05f4a3c2c301f537ae641314875e5ecc16510
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 ARHGEF38 FHAD1 DNAI1

4.46e-041659640c714e852f912b5749de4cb0895406673979b2e6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRC1 MELK FANCD2 POLQ

4.46e-0416596488681101d7cf60b99b8ace5d8c0944323b937306
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GMFG TRBC2 TRBC1 UNC13A

4.46e-041659642ebabe6fdbcf8765bcf9d98faf20da783c9d113d
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 ARHGEF38 FHAD1 DNAI1

4.46e-0416596482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 ADCY7 FAM83B RAB27B

4.46e-04165964f6887c64af0f26e33316bc5587487e24d76ece2a
Diseaseblue cone monochromacy (implicated_via_orthology)

OPN1MW OPN1MW2 OPN1MW3

1.25e-074943DOID:0050679 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

POLR1A TRIM58 EMID1 LRRC37A2 APOB PRC1 VSTM4 CYFIP1 PMPCA CCT5 KIAA1217 SIMC1 RNF10 PDS5A EIF4G3

2.25e-0513479415EFO_0005192
Diseasebreast carcinoma

EMID1 PRC1 MAST2 FAM83B ITPR1 SPPL2A NF2 PKLR STAG3L2 STAG3L3 PHIP

3.99e-0410199411EFO_0000305
Diseasereticulocyte count

SPIRE2 COPB1 TRIM58 DTNB EMID1 MAST2 VSTM4 PTPRN RNF10 PKLR DEPDC5

4.92e-0410459411EFO_0007986
Diseasesuperior frontal gyrus grey matter volume measurement

CCKAR EIF4G3

8.91e-0414942EFO_0006516
Diseaseceramide measurement

POLR1A APOB SGPP1 CCNG1 CHP2

9.48e-04235945EFO_0010222
Diseasewhite matter microstructure measurement

SPIRE2 APOB MAST2 CYFIP1 RERGL EIF4G3

1.57e-03390946EFO_0005674
Diseasecognitive function measurement

GAD1 CCDC146 CCNG1 CKM RERGL TBC1D22A KIAA1217 AP3B2 RNF10 PDS5A RAB27B KDM4B

1.99e-0314349412EFO_0008354
DiseaseBronchiectasis

DNAI1 CCDC40

2.23e-0322942C0006267
Diseaseotitis media (implicated_via_orthology)

PHEX NF2

2.23e-0322942DOID:10754 (implicated_via_orthology)
Diseasepeptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease

DEPDC5 CNGA4

2.65e-0324942EFO_0003948, EFO_0009923, MONDO_0004247
DiseaseAlzheimer disease, polygenic risk score

MAST2 MELK CKM SPPL2A UBE2V2 EIF4G3 KDM4B

2.72e-03586947EFO_0030082, MONDO_0004975
DiseaseAlzheimer disease, high density lipoprotein cholesterol measurement

APOB SPPL2A

3.10e-0326942EFO_0004612, MONDO_0004975
Diseasediabetes mellitus (implicated_via_orthology)

GAD1 PTPRN

3.10e-0326942DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QNIIMVLKDRMKIRE

UNC13A

621

Q9UPW8
LMELEVELMKFVSKV

FAM209A

116

Q5JX71
IKDRLIKIMSMQGQI

AMN1

36

Q8IY45
MLKKEIAMLKLEVAT

ANKRD30B

1086

Q9BXX2
DEMIGKIIKHLKMVV

CCDC7

81

Q96M83
MMAKREKIIKELIQT

ARHGEF38

91

Q9NXL2
QKLEVEHVMMRKIIK

ANKRD36

1876

A6QL64
LEVEHVMMRKIIKKQ

ANKRD36B

1316

Q8N2N9
LIKLSQAAKIMERMV

DNAI1

276

Q9UI46
MAKKRVIRMLIVIVV

CCKAR

306

P32238
ISMGMKLAIIERLKE

ADCY7

241

P51828
DSLKLEAMKRIVAMI

AP3B2

51

Q13367
MEIEKDLKMVVVNKI

RAD51AP2

1011

Q09MP3
EKAVETLLDLIMKRM

RAB27B

171

O00194
KAEKEVTRMVVVMVL

OPN1MW3

261

P0DN78
ITTDEMIKRLKMVVK

PDS5A

36

Q29RF7
KAEKEVTRMVVVMVL

OPN1MW2

261

P0DN77
ILTGEMVAIKIMDKN

MELK

31

Q14680
VSDLMRMEKIVLEKV

CCNG1

131

P51959
LEVENVMMRKIIKKQ

ANKRD36C

1741

Q5JPF3
VMMRKIIKKQDEQIE

ANKRD36C

1746

Q5JPF3
LVEVIAMIKGLQVLM

CYFIP1

451

Q7L576
MAIDIMQKMLEEQLI

DEPDC5

1226

O75140
LIDMVLNRMAKGVKE

PTPRN

921

Q16849
KNILMMTVELEKLIV

LRRC37A3

1006

O60309
KTGFLIIVLVMIAME

MAGEA1

191

P43355
KNILMMTVELEKLIL

LRRC37A2

1006

A6NM11
KNILMMTVELEKLIL

LRRC37A

1006

A6NMS7
AIIMKVDKDRQMVVL

GMFG

31

O60234
MVMDTKLKIIEILQF

ITPR1

976

Q14643
VFVLMEQITLKKMRE

GAD1

221

Q99259
KMIKEARKVIALVMD

FAM83B

141

Q5T0W9
VVLNDVMIFKVKMLL

FAM135A

81

Q9P2D6
VMIFKVKMLLDERKI

FAM135A

86

Q9P2D6
MRELTINIKMKEDLI

KIF27

726

Q86VH2
MLIVEKMLEVFHAIK

COPB1

436

P53618
KDMVKISMDVFVRIL

KDM4B

311

O94953
VERLKEMIKAGMNIA

PKLR

101

P30613
MEQKVLEAEVLALKM

NF2

426

P35240
KAEKEVTRMVVVMVL

OPN1MW

261

P04001
QVMLVRKGQAVELMK

PPM1E

351

Q8WY54
VEMKVKIIRTIDQML

APOB

2666

P04114
TKTKMIMVEERLILQ

FHAD1

886

B1AJZ9
IMVEERLILQQKMVK

FHAD1

891

B1AJZ9
VTMKMLVGDIIQIRK

DOCK2

381

Q92608
LIEENKMDLLGMVVV

POLQ

201

O75417
LKQQEKMIRAMELAV

CCDC40

951

Q4G0X9
LMVQLEELMKLLKEE

DTNB

506

O60941
LKIAEMKEAMRTLIF

ADA2

66

Q9NZK5
VAFVMQLVKKLMIII

MAST2

406

Q6P0Q8
ELMVQLEGLMKLLKT

DTNA

541

Q9Y4J8
VLEEVMMKSAFILKI

ERMARD

256

Q5T6L9
RLKVLEAKMTMLTVI

EMID1

146

Q96A84
EDLKIKIMLGISLMT

EQTN

176

Q9NQ60
MDGMTIKENIIKVAI

SART3

861

Q15020
LLKELLDLQKDMVVM

RYR1

4011

P21817
IGELFKLKMLTEAIM

EIF4G3

896

O43432
EMEKIFVRLEMKIIK

CMTR1

711

Q8N1G2
TIKLVRQVMEKRVVM

MED1

36

Q15648
RVMMAELEKTVKKIE

FANCD2

1236

Q9BXW9
LDMIDKEQKSIVIMV

PDCL

171

Q13371
VREMVEIITKEFILM

PMPCA

401

Q10713
VMKDVVLIRKLLALM

POLR1A

331

O95602
VEMMFIRIIKDILIN

RERGL

161

Q9H628
QLVVDGVKLMVEMEK

CKM

351

P06732
MEERMIEVEQKLKLV

NIN

2036

Q8N4C6
EVVKKHIKELLDMMI

PRC1

41

O43663
IGMVFVLIIRDVMKK

SGPP1

371

Q9BX95
QELLRAMMKKAELEI

KIAA1217

671

Q5T5P2
VDVLKEAYMLLMKIQ

SIMC1

521

Q8NDZ2
TQMVRMILKIDDIRK

CCT5

521

P48643
YKKVQLVRLVGMMLL

OCRL

311

Q01968
MLLVKNIQLEDGKMI

ALDH1L1

286

O75891
MERFEEMVVKVLIKL

CCDC136

846

Q96JN2
MKELVVNLLRMTQIK

CCDC146

451

Q8IYE0
VLRADILDQMRKMIK

ASPA

186

P45381
LEKMDVEQKMSIRIL

CHP2

181

O43745
QTIMEEKGREILLKM

CNGA4

461

Q8IV77
MELREQELMKIVGIK

PHIP

996

Q8WWQ0
LVSALVLMAMVKRKD

TRBC1

161

P01850
VMDVRRVLVKAEMEK

SPIRE2

541

Q8WWL2
TITMQLMKREKGVLV

RNF10

291

Q8N5U6
IGMILTFVVLVLMKK

SPPL2A

446

Q8TCT8
QSKIEDMRIKVMILE

NUP188

906

Q5SRE5
MKSVLRLEIKIAEIM

PHEX

271

P78562
LILILKNMEGVLMDV

STAG3L2

111

P0CL84
QMKVKMLEELVSRID

TBC1D22A

386

Q8WUA7
VLEKLPVEAMVTILM

WRNIP1

376

Q96S55
MLKLVIIENMAEIML

VN1R5

1

Q7Z5H4
VILQLGKEDKLRMME

ZNF233

56

A6NK53
KVVLQELRRLMMSKE

UBE2V2

116

Q15819
LILILKNMEGVLMDV

STAG3L3

111

P0CL85
LVSALVLMAMVKRKD

TRBC2

161

A0A5B9
QEALMVKMTKLRVVQ

VSTM4

71

Q8IW00
LKIVVGALQMAEILM

TRIP12

896

Q14669
VKLQMALELMRKELE

TRIM58

141

Q8NG06
QKEGLEIVKMVMISL

XRCC5

201

P13010
VQVDVKMAILQIMKE

TRIM28

291

Q13263
KGDVMVALEMLLLRK

TRERF1

856

Q96PN7
MEVLKDSMVLAILGK

KCNH8

596

Q96L42