Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

HS3ST4 HS3ST3B1 HS3ST3A1

1.04e-0571353GO:0008467
GeneOntologyMolecularFunctionarmadillo repeat domain binding

TCF7L2 LEF1 CNOT1

2.46e-0591353GO:0070016
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

HS3ST3B1 HS3ST3A1

4.54e-0521352GO:0033872
GeneOntologyMolecularFunctiongamma-catenin binding

TCF7L2 CDH1 LEF1

6.36e-05121353GO:0045295
GeneOntologyMolecularFunctiongated channel activity

CACNA1A GABRR1 GABRR2 ANO10 KCNH6 CLCN3 P2RX6 CNGB3 CACNA1G CACNG4

9.31e-0533413510GO:0022836
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

HS3ST4 HS3ST3B1 HS3ST3A1

1.30e-04151353GO:0034483
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1B LRP1 LRP2

1.59e-04161353GO:0005041
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A GABRR1 GABRR2 ANO10 KCNH6 CLCN3 P2RX6 CNGB3 LRRC8A CACNA1G CACNG4

2.91e-0445913511GO:0005216
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1B LRP1 LRP2

3.68e-04211353GO:0030228
GeneOntologyMolecularFunctionsulfotransferase activity

CHST12 HS3ST4 HS3ST3B1 HS3ST3A1

5.22e-04551354GO:0008146
GeneOntologyMolecularFunctiondioxygenase activity

HSPBAP1 JMJD6 KDM8 BBOX1 ALOX12B

5.38e-04981355GO:0051213
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRR1 GABRR2 ANO10 CLCN3 LRRC8A

6.76e-041031355GO:0005253
GeneOntologyMolecularFunctionchannel activity

CACNA1A GABRR1 GABRR2 ANO10 KCNH6 CLCN3 P2RX6 CNGB3 LRRC8A CACNA1G CACNG4

8.90e-0452513511GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A GABRR1 GABRR2 ANO10 KCNH6 CLCN3 P2RX6 CNGB3 LRRC8A CACNA1G CACNG4

9.04e-0452613511GO:0022803
GeneOntologyMolecularFunctiontelomerase activity

TERF2 DKC1

9.32e-0471352GO:0003720
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A GABRR1 GABRR2 ANO10 NDUFB9 SFXN1 KCNH6 CLCN3 P2RX6 CNGB3 LRRC8A SLC9A7 CACNA1G CACNG4

9.69e-0479313514GO:0015075
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

HSPBAP1 JMJD6 KDM8 BBOX1

9.83e-04651354GO:0016706
GeneOntologyMolecularFunctionvolume-sensitive anion channel activity

CLCN3 LRRC8A

1.58e-0391352GO:0005225
GeneOntologyMolecularFunctiontransferase activity, transferring sulphur-containing groups

CHST12 HS3ST4 HS3ST3B1 HS3ST3A1

1.59e-03741354GO:0016782
GeneOntologyBiologicalProcessheparan sulfate proteoglycan metabolic process

SULF1 HS3ST4 HS3ST3B1 HS3ST3A1

3.80e-06171344GO:0030201
GeneOntologyBiologicalProcessamyloid-beta clearance by transcytosis

RAB11B RAB11A LRP1

9.21e-0671343GO:0150093
GeneOntologyBiologicalProcesstranscytosis

RAB11B RAB11A LRP1 LRP2

1.64e-05241344GO:0045056
GeneOntologyBiologicalProcesscirculatory system development

FOXM1 EEF1AKMT4-ECE2 TCF7L2 C1GALT1 LMO4 NEB FZD4 NPHP3 AGO1 EGF JMJD6 MTOR SULF1 GALNT11 VCAN TLR3 LRP1 LRP2 CACNA1G ASB4 TAB1 LEF1 TBX1 FOXJ1

1.77e-05144213424GO:0072359
GeneOntologyBiologicalProcesstube morphogenesis

FOXM1 TCF7 TCF7L2 C1GALT1 LMO4 FZD4 NPHP3 AGO1 EGF JMJD6 SULF1 TLR3 LRP1 LRP2 ASB4 HS3ST3B1 HS3ST3A1 CDH1 LEF1 TBX1

3.92e-05112513420GO:0035239
GeneOntologyBiologicalProcessproteoglycan metabolic process

TCF7L2 SULF1 CHST12 HS3ST4 HS3ST3B1 HS3ST3A1

4.09e-05971346GO:0006029
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process

TCF7L2 HS3ST4 HS3ST3B1 HS3ST3A1

7.63e-05351344GO:0015012
GeneOntologyBiologicalProcessproteoglycan biosynthetic process

TCF7L2 CHST12 HS3ST4 HS3ST3B1 HS3ST3A1

9.26e-05701345GO:0030166
GeneOntologyBiologicalProcesstube development

FOXM1 TCF7 TCF7L2 C1GALT1 LMO4 FZD4 NPHP3 AGO1 EGF JMJD6 SULF1 TLR3 LRP1 LRP2 ASB4 TAB1 HS3ST3B1 HS3ST3A1 CDH1 LEF1 TBX1 FOXJ1

9.96e-05140213422GO:0035295
GeneOntologyBiologicalProcessglycoprotein biosynthetic process

TCF7L2 C1GALT1 ST6GALNAC2 STT3A GALNT11 CHST12 HS3ST4 FUT5 HS3ST3B1 HS3ST3A1

1.16e-0435713410GO:0009101
GeneOntologyBiologicalProcessglycoprotein metabolic process

TCF7L2 C1GALT1 ST6GALNAC2 STT3A SULF1 GALNT11 CHST12 HS3ST4 FUT5 HS3ST3B1 HS3ST3A1

1.18e-0443013411GO:0009100
GeneOntologyBiologicalProcessresponse to nickel cation

LCT CACNA1G

1.25e-0431342GO:0010045
GeneOntologyBiologicalProcessamyloid-beta clearance

RAB11B RAB11A LRP1 LRP2

1.30e-04401344GO:0097242
GeneOntologyBiologicalProcessmonoatomic anion transport

GABRR1 GABRR2 RAB11B ANO10 CLCN3 MTOR LRRC8A

1.96e-041831347GO:0006820
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

GABRR1 GABRR2 ANO10 CLCN3 MTOR LRRC8A

2.44e-041341346GO:0098661
GeneOntologyBiologicalProcesscardiac septum development

LMO4 NPHP3 LRP1 LRP2 TAB1 TBX1

2.44e-041341346GO:0003279
GeneOntologyBiologicalProcessembryonic genitalia morphogenesis

TCF7 TCF7L2

2.49e-0441342GO:0030538
GeneOntologyCellularComponentGolgi membrane

EEF1AKMT4-ECE2 RAB11A C1GALT1 ST6GALNAC2 CLCN3 MBTPS2 MTOR GALNT11 TLR3 SLC9A7 CHST12 HS3ST4 FUT5 HS3ST3B1 HS3ST3A1 RIC1

1.57e-0572113416GO:0000139
GeneOntologyCellularComponentCul5-RING ubiquitin ligase complex

PCMTD1 ARIH2 ASB4

2.99e-05101343GO:0031466
GeneOntologyCellularComponentbeta-catenin-TCF complex

TCF7 TCF7L2 LEF1

7.03e-05131343GO:1990907
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CATSPERD CACNA1G CACNG4

2.14e-04461344GO:0005891
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1A GABRR1 GABRR2 GRM5 CLCN3 P2RX6 PTPRZ1 LRP1 CACNG4 CNTN1

2.88e-0440513410GO:0045211
GeneOntologyCellularComponentphosphorylase kinase complex

PHKB PHKG1

4.03e-0451342GO:0005964
GeneOntologyCellularComponentendocytic vesicle membrane

RAB11B RAB11A FZD4 EGF LRP1 LRP2 CACNG4

4.42e-042121347GO:0030666
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A GABRR1 GABRR2 CATSPERD KCNH6 CNGB3 LRRC8A CACNA1G CACNG4

7.54e-043781349GO:0034702
GeneOntologyCellularComponentglutamatergic synapse

CACNA1A GABRR1 RAB11A CHD4 GRM5 FZD4 CLCN3 P2RX6 MTOR PTPRZ1 LRP1 CACNG4 CDH1 CNTN1

7.74e-0481713414GO:0098978
GeneOntologyCellularComponentrecycling endosome membrane

RAB11B RAB11A CLCN3 SNX18 SLC9A7

7.78e-041121345GO:0055038
GeneOntologyCellularComponentendocytic vesicle

RAB11B RAB11A FZD4 CLCN3 EGF MTOR LRP1 LRP2 CACNG4

8.42e-043841349GO:0030139
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CATSPERD CACNA1G CACNG4

1.25e-03731344GO:0034704
GeneOntologyCellularComponentcell leading edge

LMO4 LCP1 PLEK2 DST CLCN3 PTPRZ1 AVIL SNX9 CDH1 DUOXA2

1.45e-0350013410GO:0031252
GeneOntologyCellularComponentperineuronal net

PTPRZ1 VCAN

1.77e-03101342GO:0072534
DomainCTNNB1_binding

TCF7 TCF7L2 LEF1

1.31e-0641303PF08347
DomainTCF/LEF

TCF7 TCF7L2 LEF1

1.31e-0641303IPR024940
DomainCTNNB1-bd_N

TCF7 TCF7L2 LEF1

1.31e-0641303IPR013558
DomainLdl_recept_b

LRP1B EGF LRP1 LRP2

2.13e-06141304PF00058
DomainLDLRB

LRP1B EGF LRP1 LRP2

2.13e-06141304PS51120
DomainLY

LRP1B EGF LRP1 LRP2

2.88e-06151304SM00135
DomainLDLR_classB_rpt

LRP1B EGF LRP1 LRP2

2.88e-06151304IPR000033
Domain-

LRP1B RGN EGF LRP1 LRP2

7.20e-063913052.120.10.30
Domain6-blade_b-propeller_TolB-like

LRP1B RGN EGF LRP1 LRP2

1.65e-05461305IPR011042
DomainCatenin_binding_dom

TCF7 TCF7L2 CDH1 LEF1

4.65e-05291304IPR027397
Domain-

TCF7 TCF7L2 CDH1 LEF1

4.65e-052913044.10.900.10
DomainGABAAa_rho_rcpt

GABRR1 GABRR2

4.81e-0521302IPR008057
DomainDUF5050

LRP1B LRP1

4.81e-0521302IPR032485
DomainDUF5050

LRP1B LRP1

4.81e-0521302PF16472
DomainSnx9_subfam

SNX18 SNX9

1.44e-0431302IPR014536
DomainBAR_3_WASP_bdg

SNX18 SNX9

1.44e-0431302PF10456
DomainSorting_nexin_WASP-bd-dom

SNX18 SNX9

1.44e-0431302IPR019497
DomainLDLR_class-A_CS

CFI LRP1B LRP1 LRP2

1.69e-04401304IPR023415
DomainLdl_recept_a

CFI LRP1B LRP1 LRP2

2.68e-04451304PF00057
Domain-

CFI LRP1B LRP1 LRP2

2.92e-044613044.10.400.10
DomainLDLRA_1

CFI LRP1B LRP1 LRP2

3.44e-04481304PS01209
DomainLDrepeatLR_classA_rpt

CFI LRP1B LRP1 LRP2

3.73e-04491304IPR002172
DomainLDLa

CFI LRP1B LRP1 LRP2

3.73e-04491304SM00192
DomainLDLRA_2

CFI LRP1B LRP1 LRP2

3.73e-04491304PS50068
DomainEGF_Ca-bd_CS

LRP1B EGF VCAN LRP1 LRP2

5.84e-04971305IPR018097
DomainEGF_CA

LRP1B EGF VCAN LRP1 LRP2

6.41e-04991305PS01187
DomainASX_HYDROXYL

LRP1B EGF VCAN LRP1 LRP2

6.71e-041001305PS00010
DomaincEGF

LRP1B LRP1 LRP2

7.62e-04261303PF12662
DomaincEGF

LRP1B LRP1 LRP2

7.62e-04261303IPR026823
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1B EGF VCAN LRP1 LRP2

8.74e-041061305IPR000152
DomainCupin_4

HSPBAP1 KDM8

9.87e-0471302PF08007
DomainHMG_box_dom

TCF7 TCF7L2 CHD4 LEF1

1.09e-03651304IPR009071
DomainJMJC

HSPBAP1 JMJD6 KDM8

1.41e-03321303PS51184
DomainJmjC_dom

HSPBAP1 JMJD6 KDM8

1.41e-03321303IPR003347
DomainJmjC

HSPBAP1 JMJD6 KDM8

1.54e-03331303SM00558
DomainEGF_CA

LRP1B EGF VCAN LRP1 LRP2

1.64e-031221305SM00179
DomainEGF-like_Ca-bd_dom

LRP1B EGF VCAN LRP1 LRP2

1.76e-031241305IPR001881
DomainEGF

LRP1B EGF VCAN LRP1 LRP2

1.89e-031261305PF00008
DomainSulfotransfer_1

HS3ST4 HS3ST3B1 HS3ST3A1

1.99e-03361303PF00685
DomainSulfotransferase_dom

HS3ST4 HS3ST3B1 HS3ST3A1

1.99e-03361303IPR000863
DomainHAT

ZFC3H1 CRNKL1

2.09e-03101302SM00386
DomainVDCCAlpha1

CACNA1A CACNA1G

2.09e-03101302IPR002077
DomainHAT

ZFC3H1 CRNKL1

2.09e-03101302IPR003107
DomainEGF_CA

LRP1B EGF LRP1 LRP2

3.06e-03861304PF07645
DomainPX

PIK3C2G SNX18 SNX9

3.54e-03441303SM00312
DomainPI3/4_kinase_CS

PIK3C2G MTOR

4.76e-03151302IPR018936
DomainPX

PIK3C2G SNX18 SNX9

4.81e-03491303PF00787
DomainPX

PIK3C2G SNX18 SNX9

5.09e-03501303PS50195
Domain-

PIK3C2G SNX18 SNX9

5.38e-035113033.30.1520.10
Domain-

PIK3C2G MTOR

5.41e-031613021.10.1070.11
DomainPI3Kc

PIK3C2G MTOR

5.41e-03161302SM00146
DomainPhox

PIK3C2G SNX18 SNX9

5.68e-03521303IPR001683
Domainp53-like_TF_DNA-bd

TBX10 FUT5 TBX1

5.99e-03531303IPR008967
DomainHMG_box

TCF7 TCF7L2 LEF1

5.99e-03531303PF00505
DomainEGF_3

ADAM30 LRP1B EGF VCAN LRP1 LRP2

6.08e-032351306PS50026
DomainTF_T-box

TBX10 TBX1

6.11e-03171302IPR001699
DomainTBOX

TBX10 TBX1

6.11e-03171302SM00425
DomainTF_T-box_CS

TBX10 TBX1

6.11e-03171302IPR018186
Domain-

TBX10 TBX1

6.11e-031713022.60.40.820
DomainTBOX_3

TBX10 TBX1

6.11e-03171302PS50252
DomainT-box

TBX10 TBX1

6.11e-03171302PF00907
DomainTBOX_1

TBX10 TBX1

6.11e-03171302PS01283
DomainTBOX_2

TBX10 TBX1

6.11e-03171302PS01264
DomainHMG_BOX_2

TCF7 TCF7L2 LEF1

6.31e-03541303PS50118
DomainHMG

TCF7 TCF7L2 LEF1

6.31e-03541303SM00398
Domain-

TCF7 TCF7L2 LEF1

6.64e-035513031.10.30.10
DomainPI3_PI4_kinase

PIK3C2G MTOR

6.84e-03181302PF00454
DomainPI3_4_KINASE_1

PIK3C2G MTOR

6.84e-03181302PS00915
DomainPI3_4_KINASE_2

PIK3C2G MTOR

6.84e-03181302PS00916
DomainPI3/4_kinase_cat_dom

PIK3C2G MTOR

6.84e-03181302IPR000403
DomainPI3_4_KINASE_3

PIK3C2G MTOR

6.84e-03181302PS50290
PathwayKEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7 TCF7L2 CDH1 LEF1

2.23e-0781084M47413
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7 TCF7L2 LEF1

8.60e-0661083MM15542
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7 TCF7L2 LEF1

8.60e-0661083M47736
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY

TCF7 TCF7L2 LEF1

1.50e-0571083M47465
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7 TCF7L2 LEF1

2.38e-0581083MM17229
PathwayREACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS

TCF7 TCF7L2 LEF1

2.38e-0581083M27359
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7 TCF7L2 LEF1

2.38e-0581083M27821
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TCF7 TCF7L2 VCAN CACNA1G CDH1 LEF1

3.34e-05801086M223
PathwayKEGG_ENDOMETRIAL_CANCER

TCF7 TCF7L2 EGF CDH1 LEF1

4.69e-05521085M19877
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY

TCF7 TCF7L2 LEF1

5.05e-05101083M47486
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7 TCF7L2 LEF1

5.05e-05101083MM15156
PathwayKEGG_THYROID_CANCER

TCF7 TCF7L2 CDH1 LEF1

6.68e-05291084M523
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY

TCF7 TCF7L2 LEF1

9.15e-05121083M47410
PathwayREACTOME_CA2_PATHWAY

TCF7 TCF7L2 FZD4 AGO1 LEF1

1.10e-04621085M27321
PathwayWP_ENDOMETRIAL_CANCER

TCF7 TCF7L2 EGF CDH1 LEF1

1.19e-04631085M39623
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7 TCF7L2 LEF1

1.50e-04141083M27402
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7 TCF7L2 LEF1

2.28e-04161083MM17241
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7 TCF7L2 LEF1

2.75e-04171083M48240
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TCF7 TCF7L2 LEF1

2.75e-04171083M39443
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

TCF7 TCF7L2 FZD4 LEF1

3.81e-04451084M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

TCF7 TCF7L2 FZD4 LEF1

4.15e-04461084M47409
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A GRM5 ADCY3 PHKB PHKG1 P2RX6 CACNA1G

4.34e-041781087M2890
PathwayKEGG_PROSTATE_CANCER

TCF7 TCF7L2 EGF MTOR LEF1

5.99e-04891085M13191
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

VCAN HS3ST4 HS3ST3B1 HS3ST3A1

7.67e-04541084MM14633
PathwayKEGG_BASAL_CELL_CARCINOMA

TCF7 TCF7L2 FZD4 LEF1

8.23e-04551084M17807
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1G CACNG4

8.90e-04251083M47948
PathwayWP_HIPPO_SIGNALING_REGULATION

TCF7 TCF7L2 MTOR CDH1 LEF1

9.28e-04981085M39830
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

VCAN HS3ST4 HS3ST3B1 HS3ST3A1

9.42e-04571084M692
PathwayKEGG_ACUTE_MYELOID_LEUKEMIA

TCF7 TCF7L2 MTOR LEF1

9.42e-04571084M19888
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF7 TCF7L2 LEF1

1.00e-03261083MM14793
PathwayKEGG_MELANOGENESIS

TCF7 TCF7L2 ADCY3 FZD4 LEF1

1.06e-031011085M7761
Pubmed

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

TCF7 TCF7L2 CDH1 LEF1

1.08e-0712136432414917
Pubmed

TCF transcription factors: molecular switches in carcinogenesis.

TCF7 TCF7L2 LEF1

2.33e-074136310528152
Pubmed

Mapping canonical Wnt signaling in the developing and adult retina.

TCF7 TCF7L2 LEF1

2.33e-074136317065530
Pubmed

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.

TCF7 TCF7L2 LEF1

5.82e-075136321285352
Pubmed

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

TCF7 TCF7L2 LEF1

1.16e-06613639488439
Pubmed

SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.

TCF7 TCF7L2 LEF1

1.16e-066136320128911
Pubmed

Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.

TCF7 TCF7L2 LEF1

1.16e-066136324748645
Pubmed

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.

TCF7 TCF7L2 LEF1

1.16e-066136323152144
Pubmed

Dazap2 modulates transcription driven by the Wnt effector TCF-4.

TCF7 TCF7L2 LEF1

1.16e-066136319304756
Pubmed

Mitotic internalization of planar cell polarity proteins preserves tissue polarity.

RAB11B RAB11A CDH1

2.02e-067136321743464
Pubmed

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells.

TCF7 TCF7L2 LEF1

2.02e-067136332820720
Pubmed

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

TCF7 TCF7L2 LEF1

2.02e-067136318772112
Pubmed

Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo.

TCF7 TCF7L2 LEF1

2.02e-067136319303461
Pubmed

Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm.

TCF7 TCF7L2 LEF1 FOXJ1

2.65e-0625136415186480
Pubmed

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.

RAB11B RAB11A LRP2

3.23e-068136333500317
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

TCF7 TCF7L2 VCAN LEF1

3.66e-0627136423824573
Pubmed

Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis.

TCF7 TCF7L2 LEF1

4.83e-069136317335794
Pubmed

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

RAB11B RAB11A LRP1

6.88e-0610136326005850
Pubmed

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.

TCF7 TCF7L2 CDH1

6.88e-0610136322393260
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1B LRP1 LRP2

9.43e-0611136324639464
Pubmed

Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti.

RAB11B RAB11A CDH1

9.43e-0611136337225424
Pubmed

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

TCF7 TCF7L2 LEF1

9.43e-0611136311731265
Pubmed

mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.

MTOR CDH1 LEF1 TBX1

9.47e-0634136432866472
Pubmed

Integral and associated lysosomal membrane proteins.

EGF MTOR TLR3 LRP1 LRP2 DEPDC5

1.07e-05126136617897319
Pubmed

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.

TCF7 TCF7L2 LEF1

1.25e-0512136310631168
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TCF7 TCF7L2 LEF1

1.25e-0512136311266540
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

TCF7 TCF7L2 FZD4 LEF1

1.34e-0537136435831952
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

TCF7 TCF7L2 FZD4 LEF1

1.34e-0537136415342465
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

TCF7 TCF7L2 FZD4 LEF1

1.49e-0538136418635608
Pubmed

SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane.

SNX18 SNX9

1.52e-052136220427313
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

1.52e-052136215963947
Pubmed

Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.

TCF7 LEF1

1.52e-052136227044748
Pubmed

Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing.

DHX38 CDC40

1.52e-05213629524131
Pubmed

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis.

TCF7 LEF1

1.52e-05213628223271
Pubmed

Interaction between variants of two glycosyltransferase genes in IgA nephropathy.

C1GALT1 ST6GALNAC2

1.52e-052136219357720
Pubmed

Induction of forkhead box M1 (FoxM1) by EGF through ERK signaling pathway promotes trophoblast cell invasion.

FOXM1 EGF

1.52e-052136226022336
Pubmed

Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms.

GABRR1 GABRR2

1.52e-052136228660714
Pubmed

Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.

VCAN CDH1

1.52e-052136223002209
Pubmed

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching.

TCF7L2 LEF1

1.52e-052136221599871
Pubmed

GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.

GABRR1 GABRR2

1.52e-052136219536785
Pubmed

Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.

HS3ST3B1 HS3ST3A1

1.52e-052136222475533
Pubmed

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1.

TCF7 LEF1

1.52e-05213629462507
Pubmed

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation.

TBX10 TBX1

1.52e-052136215703190
Pubmed

A role for Rab11 in the homeostasis of the endosome-lysosomal pathway.

RAB11B RAB11A

1.52e-052136230981667
Pubmed

LRRC8A anion channels modulate vascular reactivity via association with myosin phosphatase rho interacting protein.

MPRIP LRRC8A

1.52e-052136237310356
Pubmed

Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function.

TCF7 LEF1

1.52e-052136238169425
Pubmed

Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.

C1GALT1 ST6GALNAC2

1.52e-052136224398680
Pubmed

Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials.

TCF7 LEF1

1.52e-052136222111711
Pubmed

CHD4-mediated loss of E-cadherin determines metastatic ability in triple-negative breast cancer cells.

CHD4 CDH1

1.52e-052136229305962
Pubmed

Cell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells.

TCF7 LEF1

1.52e-052136226490636
Pubmed

The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.

GABRR1 GABRR2

1.52e-05213629153229
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

1.52e-052136234445520
Pubmed

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.

TCF7 LEF1

1.52e-052136216424171
Pubmed

Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina.

GABRR1 GABRR2

1.52e-052136212019334
Pubmed

DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting.

MTOR DEPDC5

1.52e-052136236044864
Pubmed

DEPDC5 mutations in familial and sporadic focal epilepsy.

MTOR DEPDC5

1.52e-052136228170089
Pubmed

Gene for lymphoid enhancer-binding factor 1 (LEF1) mapped to human chromosome 4 (q23-q25) and mouse chromosome 3 near Egf.

EGF LEF1

1.52e-05213621783375
Pubmed

A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.

HS3ST3B1 HS3ST3A1

1.52e-052136210520990
Pubmed

Expression of LEF1 and TCF1 (TCF7) proteins associates with clinical progression of nasopharyngeal carcinoma.

TCF7 LEF1

1.52e-052136230918012
Pubmed

TCF7 and LEF-1 downregulation in sepsis promotes immune suppression by inhibiting CD4+ T cell proliferation.

TCF7 LEF1

1.52e-052136237741305
Pubmed

Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.

HS3ST3B1 HS3ST3A1

1.52e-052136215304505
Pubmed

Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes.

EGF VCAN

1.52e-052136222493503
Pubmed

Localization of am3 using EL congenic mouse strains.

EGF LEF1

1.52e-052136215790735
Pubmed

Rab11 regulates E-cadherin expression and induces cell transformation in colorectal carcinoma.

RAB11A CDH1

1.52e-052136225117932
Pubmed

Subthreshold membrane potential oscillations in inferior olive neurons are dynamically regulated by P/Q- and T-type calcium channels: a study in mutant mice.

CACNA1A CACNA1G

1.52e-052136220547676
Pubmed

Mutations in mammalian target of rapamycin regulator DEPDC5 cause focal epilepsy with brain malformations.

MTOR DEPDC5

1.52e-052136224585383
Pubmed

Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).

RAB11B RAB11A

1.52e-052136222129970
Pubmed

RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells.

RAB11B RAB11A

1.52e-052136237424454
Pubmed

FOXM1 and CHD4 expression is associated with chemoresistance in hepatoblastoma.

FOXM1 CHD4

1.52e-052136238761648
Pubmed

Tcf1 and Lef1 provide constant supervision to mature CD8+ T cell identity and function by organizing genomic architecture.

TCF7 LEF1

1.52e-052136234615872
Pubmed

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas.

TCF7L2 LEF1

1.52e-052136223224985
Pubmed

Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells.

TCF7L2 VCAN

1.52e-052136219269971
Pubmed

TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells.

RAB11B MTOR LRP2 CDH1

1.65e-0539136435781329
Pubmed

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.

EGF HS3ST4 HS3ST3B1 HS3ST3A1 CDH1

1.71e-0581136539217171
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A KCNH6 CLCN3 P2RX6 CACNA1G CACNG4

1.88e-05139136616985003
Pubmed

Role of CD34 family members in lumen formation in the developing kidney.

RAB11B RAB11A CDH1

2.06e-0514136327542690
Pubmed

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.

TCF7 TCF7L2 LEF1

2.06e-0514136315226261
Pubmed

The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.

CHD4 CDH1 LEF1

2.06e-0514136317360773
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1B LRP1 LRP2

2.06e-0514136315082773
Pubmed

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.

TCF7 TCF7L2 LEF1

2.06e-0514136310090727
Pubmed

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.

TCF7 TCF7L2 LEF1

2.06e-0514136333195246
Pubmed

Phases of canonical Wnt signaling during the development of mouse intestinal epithelium.

TCF7 TCF7L2 LEF1

2.57e-0515136317681174
Pubmed

β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.

TCF7 LEF1 FOXJ1

2.57e-0515136322421361
Pubmed

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

TCF7 TCF7L2 LEF1

2.57e-0515136315866165
Pubmed

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.

PTPRZ1 VCAN MMP17

2.57e-0515136338871984
Pubmed

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.

TCF7 TCF7L2 LEF1

3.16e-0516136315057272
Pubmed

Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci.

HS3ST4 HS3ST3B1 HS3ST3A1

3.16e-051613639988767
Pubmed

Hedgehog regulation of epithelial cell state and morphogenesis in the larynx.

RAB11B RAB11A CDH1

3.82e-0517136336398878
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

OXR1 USP25 CHD4 NCAPH2 ZFC3H1 LMO4 LRP1B MPRIP CRNKL1 DST LMO2 SULF1 ARIH2 LRP1 LRP2 USPL1

4.47e-0512851361635914814
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

TCF7L2 FZD4 CDH1 LEF1

4.48e-0550136427510977
Pubmed

Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation.

GABRR1 GABRR2

4.54e-05313629839716
Pubmed

Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1.

RAB11A LRP1

4.54e-053136223640058
Pubmed

The pro-osteogenic action of beta-catenin requires interaction with BMP signaling, but not Tcf/Lef transcriptional activity.

TCF7 LEF1

4.54e-053136218247340
Pubmed

Contactin-1 reduces E-cadherin expression via activating AKT in lung cancer.

CDH1 CNTN1

4.54e-053136223724143
Pubmed

Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling.

TCF7 CDH1

4.54e-053136217043652
Pubmed

Differential expression of LEF1/TCFs family members in colonic carcinogenesis.

TCF7 LEF1

4.54e-053136227433921
Pubmed

Cutting edge: generation of memory precursors and functional memory CD8+ T cells depends on T cell factor-1 and lymphoid enhancer-binding factor-1.

TCF7 LEF1

4.54e-053136222875805
Pubmed

Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4.

LMO4 LMO2

4.54e-053136212727888
Pubmed

Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells.

EGF CDH1

4.54e-053136221752154
Pubmed

Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion.

EGF CDH1

4.54e-053136225533808
GeneFamilyLow density lipoprotein receptors

LRP1B LRP1 LRP2

3.75e-0513943634
GeneFamilySulfotransferases, membrane bound

CHST12 HS3ST4 HS3ST3B1 HS3ST3A1

3.97e-0537944763
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1G CACNG4

3.24e-0426943253
GeneFamilySorting nexins|PX-BAR domain containing

SNX18 SNX9

1.71e-03129421290
ToppCellsevere_COVID-19-CD8+_T_naive|World / disease group, cell group and cell class (v2)

TCF7 CATSPERD SFXN1 P2RX6 LEF1 ALOX12B FOXJ1

4.63e-071531367422483445af49c277fc8962d76a46ffafd872422
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A GRM5 LRP1B PTPRZ1 VCAN MMP17 CNTN1

5.06e-07155136777fdae85d36efb776db977eb424b32487ef222e4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM5 TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

1.84e-061881367a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM5 TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

1.84e-061881367c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM5 PTPRZ1 VCAN CACNA1G CACNG4 MMP17 CNTN1

1.98e-0619013676c7e1086c0a274cd5527c3104106e372811c9905
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A GRM5 PTPRZ1 VCAN CACNG4 MMP17 CNTN1

2.43e-061961367f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A GRM5 PTPRZ1 VCAN CACNG4 MMP17 CNTN1

2.43e-061961367671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellVE-mono1-|VE / Condition, Cell_class and T cell subcluster

PLBD1 LILRA2 APOBEC3B LMO2 VCAN LRP1 SIGLEC1

2.60e-0619813672959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCellVE-mono1|VE / Condition, Cell_class and T cell subcluster

PLBD1 LILRA2 APOBEC3B LMO2 VCAN LRP1 SIGLEC1

2.60e-061981367c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1 SIGLEC1

2.60e-06198136706201b34d3e38f22c93b759511f7b376504bac06
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1 SIGLEC1

2.60e-0619813671ca91559fef231896e16180f5e050155c38f7cfa
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM5 LRP1B VCAN LRP1 CACNG4 MMP17 CNTN1

2.69e-061991367333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM5 LRP1B VCAN LRP1 CACNG4 MMP17 CNTN1

2.69e-061991367e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

P2RX6 PIK3C2G PTPRZ1 ALOX12B MAP3K19 FOXJ1 DUOXA2

2.78e-06200136796701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellCaecum-(4)_Monocyte-(40)_Monocyte|Caecum / shred on region, Cell_type, and subtype

PLBD1 LILRA2 TCF7L2 LIPN VCAN LRP1 TM4SF19

2.78e-062001367b078058efc51f0ff4d92123b712933b32824c655
ToppCellCaecum-(4)_Monocyte|Caecum / shred on region, Cell_type, and subtype

PLBD1 LILRA2 TCF7L2 LIPN VCAN LRP1 TM4SF19

2.78e-0620013676bfd6ab395e09087aeedc9a7c9ada1b4b8a26194
ToppCellCaecum-Monocyte|Caecum / Region, Cell class and subclass

PLBD1 LILRA2 TCF7L2 LIPN VCAN LRP1 TM4SF19

2.78e-0620013679e8d38d024a315512521b349e8ac7caa56219daf
ToppCellCaecum-Monocyte-Monocyte|Caecum / Region, Cell class and subclass

PLBD1 LILRA2 TCF7L2 LIPN VCAN LRP1 TM4SF19

2.78e-062001367d33619b6c721eae3ebe50fba6b9d31fa99f2248f
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1 SIGLEC1

2.78e-0620013674943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GABRR1 GABRR2 RGN AVIL HS3ST3B1

3.41e-06751365730a08f846a155d2c892259f2c610081d40fc2c8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GABRR1 GABRR2 RGN AVIL HS3ST3B1

3.41e-06751365f0185de0ce497997df1027a51c099d91294bba07
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GABRR1 GABRR2 RGN AVIL HS3ST3B1

3.41e-0675136559fe56388697037b335f334cb3461f15c7b3b506
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXM1 CACNA1A ST6GALNAC2 PIK3C2G IFRD2 METTL27

1.30e-05168136608f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1B ADCY3 HSPA12A LRP1 MMP17 CNTN1

1.39e-0517013665570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLBD1 TCF7L2 LMO4 LCP1 CD53 LRP1

1.87e-0517913666d2458a887047b5c20389f08345ff5aac7c683e6
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBOAT4 ST6GALNAC2 PLEK2 DST SULF1 HS3ST4

1.93e-05180136667c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellmetastatic_Brain-Myeloid_cells-Pleural_Mac|metastatic_Brain / Location, Cell class and cell subclass

PLBD1 LILRA2 LCP1 APOBEC3B VCAN CD53

1.93e-0518013667de1c8ab1152fa517c6b4830d93ff53a19fca3d7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OXR1 GRM5 LGI2 UGT2A3 LRP2 L3MBTL4

1.99e-0518113666956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPRIP FZD4 DST EGF TLR3 LRRC8A

2.05e-0518213664c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

TCF7 STT3A PHKB MBTPS2 TLR3 TMCC1

2.18e-0518413660e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRZ1 SULF1 VCAN LRP1 CACNG4 CNTN1

2.18e-051841366278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 LMO4 ADCY3 LRP1 SIGLEC1 MARVELD2

2.18e-0518413668fa30789c9d583188667cf375d2218e392dd40bc
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRZ1 SULF1 VCAN LRP1 CACNG4 CNTN1

2.18e-0518413668d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

STT3A PHKB MBTPS2 TLR3 ETNK1 TMCC1

2.25e-0518513661979d189c204f4c2893e3170a514ee7d5523406c
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 ADCY3 HSPA12A DST MARVELD2 CDH1

2.32e-051861366f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

TCF7L2 USP25 LMO4 LCP1 DST LRP1

2.32e-05186136633d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 ADCY3 HSPA12A DST MARVELD2 CDH1

2.32e-0518613668f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCelldroplet-Marrow-nan-21m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 LMO4 LCP1 CD53 CHST12 TMCC1

2.39e-05187136620b25b0d08550a1e8e997c5ce67d8e34bf7fc398
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 ADCY3 HSPA12A DST MARVELD2 CDH1

2.54e-05189136698f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 ADCY3 HSPA12A DST MARVELD2 CDH1

2.54e-051891366f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B DST EGF PIK3C2G SNX9 CDH1

2.54e-051891366e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

2.61e-0519013669b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

2.61e-051901366d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

2.69e-051911366ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 PTPRZ1 VCAN LRP1 CACNG4 CNTN1

2.69e-051911366478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PIK3C2G PTPRZ1 LRP2 MARVELD2 CDH1 FOXJ1

2.77e-051921366b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DST PTPRZ1 LRP1 CACNG4 BBOX1 TBX1

2.94e-05194136608fad7591c20568de797cf8e206de2d0b1d78aab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LILRA2 LIPN LCP1 VCAN CD53 MMP17

3.02e-0519513661d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellCOVID-19_Mild-PLT_5|COVID-19_Mild / Disease Group and Platelet Clusters

PLBD1 TCF7 LCP1 VCAN CD53 LEF1

3.02e-051951366bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCellmild_COVID-19_(asymptomatic)-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

LILRA2 TCF7L2 APOBEC3B LMO2 SNX18 SIGLEC1

3.02e-051951366eb809331557f8c40de45b1208cbc49b621930a4b
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

TCF7L2 LCP1 VCAN CD53 LRP1 SIGLEC1

3.02e-05195136655e25f702af19146a161861cfd15f40bbda1dc35
ToppCellVE-granulo1-|VE / Condition, Cell_class and T cell subcluster

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.11e-051961366ab3f2ce294c7e503d86254a195be0cf500a2c5e4
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

LILRA2 TCF7L2 LIPN LMO2 SNX18 LRP1

3.11e-051961366256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellVE-granulo1|VE / Condition, Cell_class and T cell subcluster

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.11e-0519613666dbd3acb30173d7f0b7bca0a82f435f00ca85835
ToppCell10x5'-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

PLBD1 LILRA2 TCF7L2 LIPN VCAN LRP1

3.20e-05197136667f19dd30adb03300f04219d0295bc1c1788f626
ToppCellCOVID-19_Moderate-Classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.20e-05197136698d4107e457e7399a84439acd73bf8f59598971b
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.29e-051981366d347462ba6cb1c5a59c86dffbbe914cbc1e9cf16
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.29e-051981366c5a22846bccff948f90bc1d5fe309907dcd08348
ToppCellCOVID-19_Mild-Myeloid-Classical_Monocyte|COVID-19_Mild / Disease group, lineage and cell class

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.29e-051981366e78d027a095473af555762a4d542a73f5bb2e166
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

LILRA2 TCF7L2 LMO2 VCAN LRP1 SIGLEC1

3.29e-05198136609009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.29e-051981366c49c71b34151d82b8795763bcb633c301c35f659
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.29e-0519813664780f0276546962a2fc9f1041cfe49d2919d72b2
ToppCellsevere_COVID-19-Classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

PLBD1 LILRA2 LCP1 LMO2 VCAN LRP1

3.29e-05198136640dd3333945aa0c9120296b75155c621f462dbe8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1

3.29e-051981366b19a089eb80af3428891f2ff00e53a6e11894fa3
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1

3.39e-0519913664fc03377c017209111561789226621d258291481
ToppCellSigmoid-(1)_T_cell-(14)_Tcm|Sigmoid / shred on region, Cell_type, and subtype

FOXM1 TCF7 MPRIP MTOR HS3ST3B1 LEF1

3.39e-051991366ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TCF7L2 CFI DST SULF1 VCAN LRP1

3.39e-05199136640de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellVE-granulo2|VE / Condition, Cell_class and T cell subcluster

LILRA2 APOBEC3B LMO2 VCAN LRP1 SIGLEC1

3.39e-05199136605b47fdc01eccee0eaf4c781eeff93c47fe0533e
ToppCellhealthy_donor-Myeloid|healthy_donor / Disease condition, Lineage, Cell class and subclass

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1

3.39e-051991366d41994e08f7c3f5bd865b689db8f032efbe88d24
ToppCellhealthy_donor-Myeloid-Monocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

PLBD1 LILRA2 TCF7L2 LMO2 VCAN LRP1

3.39e-051991366bd66a8d1a7cc92313328acc7c7ae0442faff951e
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLBD1 LILRA2 TCF7L2 DST LMO2 SIGLEC1

3.39e-051991366f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CFI FZD4 DST SULF1 VCAN LRP1

3.39e-05199136613ff7409e200a0b46cdb7924d15ef33639693622
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM5 LRP1B VCAN LRP1 CACNG4 CNTN1

3.39e-05199136619a97e27a4758e794ce7246d295e112b47931a48
ToppCellSigmoid-T_cell-Tcm|Sigmoid / Region, Cell class and subclass

FOXM1 TCF7 MPRIP MTOR HS3ST3B1 LEF1

3.39e-051991366f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCellVE-granulo2-|VE / Condition, Cell_class and T cell subcluster

LILRA2 APOBEC3B LMO2 VCAN LRP1 SIGLEC1

3.39e-051991366455e92047201ddd0c29a437a838e5fa135de7995
ToppCellmild_COVID-19_(asymptomatic)-Classical_Monocyte|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.39e-05199136673a98d19871ffbc3c631de330998d42e9afa6da2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LILRA2 TCF7L2 LIPN LCP1 LRP1 MMP17

3.39e-051991366ac866ae110967c5867ff4601939b79861d43df54
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLBD1 TCF7L2 LCP1 DST LRP1 SIGLEC1

3.39e-0519913668e9862907b15809d083216e7d6a0f435015e5d15
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRP1B DST LMO2 SLC9A7 SIGLEC1 CDH1

3.48e-05200136686f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate|GW08 / Sample Type, Dataset, Time_group, and Cell type.

TCF7 MSANTD2 RGN HSPA12A CYP2R1 KDM8

3.48e-052001366401d50fa394fa863fa7836344110ae5c7af3250a
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.48e-052001366621af09aae34226902c03edf556562f3ab35a7d8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLBD1 TCF7L2 LMO2 VCAN LRP1 SIGLEC1

3.48e-05200136694679f6914dab1551ce1c58542a65c339254451d
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLBD1 TCF7L2 VCAN LRP1 SIGLEC1 FAR1

3.48e-052001366934c2efc780318c66d667ca75be0de350361d351
ToppCellBronchial-10x5prime-Immune_Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLBD1 LCP1 VCAN CD53 LRP1 SIGLEC1

3.48e-052001366d97e9253df98cf6ad3ef4fb28e344ec108d02b1e
ToppCellCOVID-19-COVID-19_Mild-Myeloid-CD14+_Monocyte|COVID-19_Mild / Disease, condition lineage and cell class

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.48e-052001366f76d3647f8ab5f7be018b0697c911597198e03f5
ToppCellInfluenza-Influenza_Severe-Myeloid|Influenza_Severe / Disease, condition lineage and cell class

PLBD1 LILRA2 LCP1 LMO2 VCAN LRP1

3.48e-0520013662bf931ec2c6165698ba600b151fd30d8dd921d95
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.48e-052001366e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NRSN2 BBOX1 ALOX12B MAP3K19 FOXJ1 DUOXA2

3.48e-0520013664992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.48e-052001366b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellSevere-Myeloid-Macrophages-FCN1_high|Severe / Condition, Lineage, Cell class and cell subclass

PLBD1 LILRA2 LCP1 APOBEC3B LMO2 VCAN

3.48e-052001366449623d6786e30d493f68156b3f1ee8caf9265a6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM5 VCAN LRP1 CACNG4 MMP17 CNTN1

3.48e-052001366ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellmild-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLBD1 LILRA2 LMO2 VCAN LRP1 SIGLEC1

3.48e-052001366c8b80d4e7f70c66cbbdd0665821bcd5db69c7d35
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLBD1 LILRA2 TCF7L2 APOBEC3B LMO2 SIGLEC1

3.48e-05200136699eb02f974ddc8d1882f4a5b34d4503d6ec0a5f5
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Monocytic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PLBD1 LILRA2 LIPN LCP1 VCAN CD53

3.48e-0520013664077a85ceb8bb423c06179e16fd870ab95f8a2e8
ToppCellCOVID-19_Mild-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

MBOAT4 RGN LRP2 ASB4 SIGLEC1

4.11e-051251365e58c208b4355252ceabe04a468dd19a1f436182c
ToppCellsevere_COVID-19-Treg|World / disease group, cell group and cell class (v2)

CATSPERD SFXN1 CNGB3 HS3ST3B1 LEF1

7.54e-051421365cccc2e738eeca342cd937c4cd863571951b2257e
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

TCF7 TUBGCP6 P2RX6 GALNT11 LRRC8A

8.59e-0514613657fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCelldroplet-Fat-Scat-21m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 LCP1 GRM5 CD53 TM4SF19

1.01e-04151136579827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

P2RX6 BBOX1 ALOX12B MAP3K19 DUOXA2

1.01e-04151136581cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

P2RX6 BBOX1 ALOX12B MAP3K19 DUOXA2

1.01e-0415113659cbcbbc22965a9f0be8364e733d205dd64f2a533
Drugbaclofen

CACNA1A GABRR1 GABRR2 GRM5 ADCY3 EGF JMJD6 CACNA1G CACNG4

1.90e-061911339CID000002284
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; HL60; HT_HG-U133A

GABRR2 PLEK2 KCNH6 CNGB3 LRP1 TBX10 SIGLEC1 HS3ST3A1 CNTN1

2.55e-0619813393033_UP
Druglavendustin A

FOXM1 CACNA1A GRM5 EGF PIK3C2G CNGB3 CACNA1G CACNG4

7.59e-061711338CID000003894
DrugClotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A

TCF7 TCF7L2 DNAJC16 NCAPH2 PLEK2 PHKB MTOR TMCC1

1.76e-0519213386207_DN
DrugTiapride hydrochloride [51012-33-0]; Up 200; 11uM; HL60; HT_HG-U133A

CACNA1A RAB11B TCF7 TCF7L2 FZD4 MBTPS2 LRP2 TBX10

2.04e-0519613382331_UP
DrugEstriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A

LILRA2 KCNH6 EGF AVIL VCAN CNGB3 CACNG4 LEF1

2.12e-0519713385866_UP
DrugSulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; HL60; HT_HG-U133A

NCAPH2 PHKG1 PIGC CNGB3 LRP2 CACNA1G KDM8 LEF1

2.20e-0519813382550_UP
DrugAmpicillin trihydrate [7177-48-2]; Up 200; 10uM; PC3; HT_HG-U133A

GABRR2 RAB11B NCAPH2 NRSN2 MBTPS2 CNGB3 TAB1 LEF1

2.28e-0519913386307_UP
Drug0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A

TCF7 DNAJC16 ST6GALNAC2 CACNA1G MMP17 LEF1 TBX1 MTRF1L

2.28e-0519913383774_UP
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A

LILRA2 TCF7 TCF7L2 NCAPH2 LMO4 ADCY3 GALNT11 TNPO3

2.36e-0520013381165_DN
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

CDC45 TBX10 TBX1

3.00e-05141313DOID:0060413 (implicated_via_orthology)
DiseaseKeratosis pilaris decalvans

MBTPS2 LRP1

5.85e-0531312C0343057
Diseaseepilepsy (implicated_via_orthology)

CACNA1A LRP1B KCNH6 LRP1 ETNK1 DEPDC5

9.16e-051631316DOID:1826 (implicated_via_orthology)
DiseaseCondition, Preneoplastic

FOXM1 ZBTB8OS EGF SULF1 CDH1

1.35e-041101315C0282313
DiseasePrecancerous Conditions

FOXM1 ZBTB8OS EGF SULF1 CDH1

1.35e-041101315C0032927
DiseaseGlobal developmental delay

OXR1 RAB11A STT3A AGO1 CNOT1

3.26e-041331315C0557874
Diseaseovarian neoplasm

JMJD6 MTOR SULF1 CDH1 ALOX12B

3.37e-041341315C0919267
DiseaseMalignant neoplasm of ovary

JMJD6 MTOR SULF1 CDH1 ALOX12B

3.74e-041371315C1140680
DiseaseHelicobacter Infections

PTPRZ1 CDH1

4.05e-0471312C0079487
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

CATSPERD FUT5

4.05e-0471312EFO_0021853
DiseaseSpinocerebellar Ataxia Type 2

CACNA1A ANO10 CACNA1G

4.63e-04341313C0752121
DiseaseSpinocerebellar Ataxia Type 1

CACNA1A ANO10 CACNA1G

4.63e-04341313C0752120
DiseaseSpinocerebellar Ataxia Type 5

CACNA1A ANO10 CACNA1G

4.63e-04341313C0752123
DiseaseSpinocerebellar Ataxia Type 7

CACNA1A ANO10 CACNA1G

4.63e-04341313C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

CACNA1A ANO10 CACNA1G

4.63e-04341313C0752124
DiseaseAtaxia, Spinocerebellar

CACNA1A ANO10 CACNA1G

4.63e-04341313C0087012
DiseaseSpinocerebellar Ataxia Type 4

CACNA1A ANO10 CACNA1G

5.04e-04351313C0752122
DiseaseN-acetylcarnosine measurement

GABRR1 GABRR2

5.38e-0481312EFO_0022101
DiseaseSchizophrenia

GABRR1 TCF7L2 CHD4 GRM5 KCNH6 HSPA12A MTOR PTPRZ1 TLR3 LRP1 LRP2 TBX1

5.86e-0488313112C0036341
Diseasereticulocyte count

EEF1AKMT4-ECE2 RAB11B TCF7L2 OXR1 RAB11A LCP1 ADCY3 PLEK2 EGF IFRD2 CHST12 DEPDC5 CDH1

7.87e-04104513113EFO_0007986
DiseaseMesothelioma

JMJD6 MTOR CDH1

8.06e-04411313C0025500
DiseaseIntellectual Disability

RAB11B OXR1 RAB11A STT3A AGO1 MTOR LRP2 CACNA1G

8.90e-044471318C3714756
DiseaseCongenital Nonbullous Ichthyosiform Erythroderma

LIPN ALOX12B

1.05e-03111312C0079154
DiseaseCongenital ichthyosis of skin

LIPN ALOX12B

1.05e-03111312cv:C0020758
DiseaseColorectal Carcinoma

TCF7L2 HAT1 SFXN1 FZD4 LRP1 LRP2 CDH1 LEF1 TBX1 CNTN1

1.19e-0370213110C0009402
Diseaselung adenocarcinoma (is_implicated_in)

CHD4 LRP1B EGF

1.36e-03491313DOID:3910 (is_implicated_in)
Diseasegallbladder cancer (is_implicated_in)

LRP1B EGF

1.48e-03131312DOID:3121 (is_implicated_in)
DiseaseMetabolic Bone Disorder

CYP2R1 LRP2

1.72e-03141312C0005944
Diseasethyroid gland papillary carcinoma (is_marker_for)

CDH1 LEF1

1.72e-03141312DOID:3969 (is_marker_for)
DiseaseCarcinoma, Granular Cell

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0205644
DiseaseAdenocarcinoma, Tubular

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0205645
DiseaseAdenocarcinoma, Oxyphilic

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0205642
DiseaseCarcinoma, Cribriform

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0205643
DiseaseAdenocarcinoma, Basal Cell

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0205641
DiseaseAdenocarcinoma

TCF7L2 EGF MTOR ALOX12B

1.81e-031161314C0001418
DiseaseOsteopenia

CYP2R1 LRP2

1.98e-03151312C0029453
Diseaseurate measurement, spine bone mineral density

LCP1 SNX9 RIC1

2.21e-03581313EFO_0004531, EFO_0007701
Diseasebody mass index, type 2 diabetes mellitus

TCF7L2 MTOR

2.25e-03161312EFO_0004340, MONDO_0005148
DiseaseMammary Carcinoma, Human

FOXM1 APOBEC3B EGF JMJD6 MTOR MRPS23 CDH1 LEF1

2.44e-035251318C4704874
DiseaseMammary Neoplasms, Human

FOXM1 APOBEC3B EGF JMJD6 MTOR MRPS23 CDH1 LEF1

2.44e-035251318C1257931
DiseaseMammary Neoplasms

FOXM1 APOBEC3B EGF JMJD6 MTOR MRPS23 CDH1 LEF1

2.50e-035271318C1458155
Diseasevisfatin measurement

TAB1 HS3ST4

2.55e-03171312EFO_0801230
Diseaseserum dimethylarginine measurement

TCF7L2 C1GALT1 LRP1B

2.80e-03631313EFO_0005418
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

TCF7L2 ZFC3H1 EGF ETNK1

2.81e-031311314C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

TCF7L2 ZFC3H1 EGF ETNK1

2.81e-031311314C4552091
DiseaseJuvenile arthritis

TCF7L2 ZFC3H1 EGF ETNK1

2.81e-031311314C3495559
DiseaseJuvenile psoriatic arthritis

TCF7L2 ZFC3H1 EGF ETNK1

2.81e-031311314C3714758
DiseaseBreast Carcinoma

FOXM1 APOBEC3B EGF JMJD6 MTOR MRPS23 CDH1 LEF1

2.84e-035381318C0678222
Diseasefish consumption measurement

GRM5 DEPDC5 CNOT1

2.92e-03641313EFO_0010139
DiseaseJuvenile-Onset Still Disease

TCF7L2 ZFC3H1 EGF ETNK1

3.14e-031351314C0087031
Diseaseaggressive behaviour measurement, ADHD symptom measurement

TCF7L2 XKR6 GRM5

3.47e-03681313EFO_0007826, EFO_0007860

Protein segments in the cluster

PeptideGeneStartEntry
RDREWKKYEFHYDNV

CACNA1A

1431

O00555
QSLLFHFLDEWLYKF

ZBTB8OS

86

Q8IWT0
HWEKYNNRYTESRSF

EDDM3A

106

Q14507
DVFLLRTQAEHYLWY

AVIL

541

O75366
KVANYFDWISYHVGR

CFI

561

P05156
YAKARLWFHSNFLYI

CD53

171

P19397
FSFWKYHYDRQAEII

CATSPERD

181

Q86XM0
YKYFAHRRTWDAAER

VCAN

3181

P13611
WYKFDENYAFLHRTL

APOBEC3B

171

Q9UH17
DDLEKYWDFYHSLFT

ASB4

361

Q9Y574
DNYWEYLHNSKSFFR

GVINP1

2141

Q7Z2Y8
SHYYVLWDDNRFTAD

AGO1

761

Q9UL18
ALKKYLFYFERWENH

ARIH2

361

O95376
NTRWKEDIRYHYAEI

MSANTD2

321

Q6P1R3
YFLKAIDQYWHEDCL

LMO2

41

P25791
YDIAKHLTYENVERW

RAB11A

91

P62491
YDIAKHLTYENVERW

RAB11B

91

Q15907
RKTEYALWNYLFAAV

RIC1

906

Q4ADV7
RLYWLLKNAENEAYF

PIK3C2G

791

O75747
RWHALSREEQAKYYE

LEF1

336

Q9UJU2
EEYHLYRENKSASWV

LILRA2

56

Q8N149
AVCYENRLHWFAKYF

LRRC8A

111

Q8IWT6
LYRYAAEFLTSWENH

ANO10

376

Q9NW15
VEFSHERLEEYKWNY

DEPDC5

906

O75140
KDSLDWTRHNYYESF

JMJD6

21

Q6NYC1
KQLYHSDEFRAYDWG

LIPN

296

Q5VXI9
HWFVLADQSLRYYRD

MPRIP

406

Q6WCQ1
YWIAVSHKAPAFLYD

FAR1

351

Q8WVX9
WFDDYYLKLRPETNH

GRM5

336

P41594
HFFDRSYDKGLAWYR

HS3ST3B1

171

Q9Y662
IDYVNRRLYWADENH

LRP1B

3181

Q9NZR2
SDVGDYDHVFWYQKR

IGLV2-33

46

A0A075B6J2
ADRFLLYAMDSYWHS

LMO4

31

P61968
SLKYYRDTYHPLDDW

DST

1291

Q03001
AVDYHNERLYWADAK

LRP1

4051

Q07954
VKYWHYVRALDLSFS

KDM8

396

Q8N371
RQRLEEYFQHAWSYT

KCNH6

546

Q9H252
YRDNAYKDLAWKHGN

PCMTD1

46

Q96MG8
HSYSEEEKYAFVNWI

LCP1

116

P13796
RLAHVWLDEYKEQYF

GALNT11

401

Q8NCW6
FSFLSLDKHREWLEY

DNAJC16

656

Q9Y2G8
AEAWHLYNDVYRASQ

LCT

1576

P09848
RLLVHFDNWDDSYDY

L3MBTL4

221

Q8NA19
VNHEYLSFRDKLYWT

TUBGCP6

556

Q96RT7
HFFDRSYDKGLAWYR

HS3ST3A1

186

Q9Y663
IDYLNNDRIYWSDFK

LRP2

4236

P98164
FYHDLDPNEAKQWLY

HSPA12A

121

O43301
KWYGVRSYLHLFYED

NRSN2

21

Q9GZP1
YWRKCFQTAHFYLED

PTPRZ1

1661

P23471
YAAMLRIYKHWDFNV

PLBD1

251

Q6P4A8
AQKLHFYDRWAPDYD

METTL27

26

Q8N6F8
EWRYYFFSLFQKHNE

PAQR8

61

Q8TEZ7
QYAQRDKKHEYWFAV

OXR1

581

Q8N573
FYEISNWALFRYSAD

FZD4

456

Q9ULV1
TWRLKENYAAEYANA

DUOXA2

131

Q1HG44
AYNAYKAWLRKHGEE

EEF1AKMT4-ECE2

791

P0DPD8
RDYDHSKFWAYADYK

HSPBAP1

116

Q96EW2
DWAHLYLQRKYNDAL

ADAM30

291

Q9UKF2
SFEYDLRLVLYQHWS

CDC45

271

O75419
WHSYINFELRYKEVD

CRNKL1

346

Q9BZJ0
TLYLRHYWKDERLSF

GABRR1

121

P24046
DERWHYFLVFEKYNK

HAT1

196

O14929
AEASYRWVRHKYNFD

CACNA1G

1456

O43497
RDEDKKNHYNYGWSF

CACNG4

171

Q9UBN1
FHYNEKRIYWVDLER

EGF

81

P01133
ITNLYSVHFDEKYWR

CYP2R1

401

Q6VVX0
HFWHDVKLRFYYNTS

C3orf38

171

Q5JPI3
IVESYQIRYWAAHDK

CNTN1

836

Q12860
DFEDVLRYDEHAYKW

BBOX1

126

O75936
CASEYLWHAREKAYQ

CFAP97D2

11

A0A1B0GU71
AIYKWITDNFCYFRH

FOXJ1

146

Q92949
NLYAWRPVFDEYDHK

ADCY3

791

O60266
AKTWVRYAEFYSHEA

ALOX12B

381

O75342
VTAYIHKDSEWYNLF

MARVELD2

211

Q8N4S9
FKLTYYSHWILDDSL

MBOAT4

251

Q96T53
LYMDSWARHRIYAAF

IFRD2

421

Q12894
SSVYFKHSYEDWLEN

MBTPS2

26

O43462
DIYTWIEDHFPYFKH

FOXM1

261

Q08050
FQYVHEHYLEDADWF

C1GALT1

151

Q9NS00
WDHYDNIYITSRFLR

DCST2

351

Q5T1A1
QSQWLRAYLEAYKEF

ETNK1

366

Q9HBU6
IQDYDLFKQSYWNHR

CHD4

661

Q14839
WLYDNHKDESYLRRV

DKC1

271

O60832
HFFDRNYEKGLEWYR

HS3ST4

231

Q9Y661
QYWVHYLDHDSLANK

MAP3K19

921

Q56UN5
IHFLVYAWDSTYRKF

CDH1

96

P12830
TLYLRHYWKDERLAF

GABRR2

101

P28476
DNETLWDKLDHYYRI

PHKB

41

Q93100
NLITWQKVDYDFSYH

MCMBP

481

Q9BTE3
YVDREAHFYWRTKYE

P2RX6

361

O15547
LIDAYAFRIYGHWVK

PHKG1

346

Q16816
DLTQAWDLYYHVFRR

MTOR

2096

P42345
ELDKDHARYLSYFRW

FUT5

321

Q11128
QDIWYHEDRIRAKFY

MRPS23

61

Q9Y3D9
RSVNHRYKHFDWLYE

SNX9

281

Q9Y5X1
NELWRAKYIYDSAFH

SFXN1

66

Q9H9B4
YVDFAEFYRLWSVDH

TAB1

481

Q15750
FYSYQSLHEWFRDTD

LGI2

361

Q8N0V4
FKDQLYWRYDDHTRH

MMP17

446

Q9ULZ9
YKRGHFAELLSYWQF

NPHP3

896

Q7Z494
YAAFKRWHFETLEYF

MTRF1L

156

Q9UGC7
HLESWCVQRDKYRYF

NDUFB9

26

Q9Y6M9
QFLSAAYDRYLKLWD

CDC40

346

O60508
IFDDFREAYYWLRHN

STT3A

501

P46977
ITSNYWKFSDHYFER

ST6GALNAC2

326

Q9UJ37
LDWSLDHKIFYYIDS

RGN

156

Q15493
IHARKYQYWAVVFES

PIGC

41

Q92535
LAWRQQLYKLYEADF

CHST12

386

Q9NRB3
AAKLQDFHQWYLAAY

NCAPH2

356

Q6IBW4
DFHQWYLAAYADHAD

NCAPH2

361

Q6IBW4
SDDKPTEHYYRLLWF

CNGB3

176

Q9NQW8
EQLAYYHHDWFIFKE

CLCN3

546

P51790
KAEYLLREWVNLYHS

CNOT1

1851

A5YKK6
DDKRYRYAFHSSAWL

TBX10

121

O75333
FSKGVHYWELHVDRY

TRIM67

646

Q6ZTA4
TENAALTFLWYFYRD

XKR6

451

Q5GH73
HYYIQASSKAERAEW

PLEK2

331

Q9NYT0
HIEKLFLYSFSWDFE

USPL1

346

Q5W0Q7
YAAYIIHAYKDKDWV

TLR3

756

O15455
RRYKHFDWLYARLAE

SNX18

311

Q96RF0
PWKAAYHHFQRYSDV

SAP130

906

Q9H0E3
RRWHALSREEQAKYY

TCF7L2

386

Q9NQB0
LEEYEEWHQDYRKFR

USP25

861

Q9UHP3
KHWDALFSYVERFFS

TMCC1

636

O94876
SYKYNEWADDRRHLG

DHX38

271

Q92620
LRYSWYKNHVLLEDA

SIGLEC1

356

Q9BZZ2
RWHALSREEQAKYYE

TCF7

306

P36402
ISFNFWYRLGEHLYK

TNPO3

341

Q9Y5L0
DYHFWEEFYSKALGR

UGT2A3

226

Q6UWM9
TARWYLLRHLYAKDD

TTC37

1521

Q6PGP7
DDKRYRYAFHSSSWL

TBX1

166

O43435
WIFRLWYSFDHNYLK

SLC9A7

596

Q96T83
ELYQSARAWKDHKAY

SULF1

631

Q8IWU6
ADYWSNYEFHNRVIF

ZFC3H1

1831

O60293
RWVLKFYFHEALRAF

TERF2

96

Q15554
DLHSRNYLYDRSLWN

TM4SF19

146

Q96DZ7
YLSDEHGKCRKSFYW

ZNF658B

141

Q4V348
RAYWNASDLRYKETF

NEB

5256

P20929