Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coregulator activity

TCF4 TLE2 SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A EP300

3.81e-05562468GO:0003712
GeneOntologyMolecularFunctiontranscription coactivator activity

SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A EP300

6.53e-05303466GO:0003713
GeneOntologyMolecularFunctionretinoic acid-responsive element binding

NR2F1 RXRG

1.08e-047462GO:0044323
GeneOntologyMolecularFunctionpre-mRNA binding

CELF4 RBM20 EP300

4.32e-0464463GO:0036002
GeneOntologyMolecularFunctionpre-mRNA intronic binding

RBM20 EP300

4.64e-0414462GO:0097157
GeneOntologyMolecularFunctionSMAD binding

ZMIZ1 EP300 RNF111

1.02e-0386463GO:0046332
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

TCF4 TLE2 SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A EP300 RXRG

1.15e-031160469GO:0030674
GeneOntologyMolecularFunctionchromatin binding

TCF4 SMARCA2 SMARCD2 ARID1A TCF7L1 EP300 MEIS1

1.41e-03739467GO:0003682
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

TCF4 NACC2 FUBP1 SOX18 TCF7L1 EP300 NR2F1 RXRG MEIS1

1.86e-031244469GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

TCF4 NACC2 FUBP1 SOX18 TCF7L1 EP300 NR2F1 RXRG MEIS1

2.16e-031271469GO:0000987
GeneOntologyMolecularFunctionbeta-catenin binding

TCF4 TCF7L1 EP300

2.66e-03120463GO:0008013
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

SMARCA2 NAV2 ARID1A

3.12e-03127463GO:0008094
GeneOntologyMolecularFunctionbHLH transcription factor binding

TCF4 EP300

3.28e-0337462GO:0043425
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

SMARCA2 ARID1A

3.28e-0337462GO:0140658
GeneOntologyMolecularFunctionmolecular adaptor activity

TCF4 TLE2 SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A EP300 RXRG

3.35e-031356469GO:0060090
GeneOntologyMolecularFunctionsingle-stranded DNA binding

FUBP1 SSBP4 SSBP3

3.63e-03134463GO:0003697
GeneOntologyMolecularFunctionzinc ion binding

SEC24C UBR4 ZMIZ1 RBM20 EP300 NR2F1 RXRG

4.02e-03891467GO:0008270
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

TCF4 NACC2 FUBP1 SOX18 TCF7L1 EP300 NR2F1 RXRG MEIS1

5.42e-031459469GO:0000977
GeneOntologyBiologicalProcesspattern specification process

ERBB4 SHROOM3 SOX18 SSBP3 TCF7L1 EP300 NR2F1 MEIS1 RNF111

1.11e-06526439GO:0007389
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.20e-05144435GO:0045582
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

CDK8 TCF4 SMARCA2 SOX18 ZMIZ1 SSBP4 SSBP3 TCF7L1 EP300 NR2F1 RXRG MEIS1

1.81e-0513904312GO:0045944
GeneOntologyBiologicalProcesspositive regulation of lymphocyte differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

2.12e-05162435GO:0045621
GeneOntologyBiologicalProcessembryo development

ERBB4 SHROOM3 CELF4 COL12A1 SEC24C SOX18 ZMIZ1 SSBP3 ARID1A TCF7L1 EP300 MEIS1

2.52e-0514374312GO:0009790
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

SMARCA2 SMARCD2 ARID1A

2.97e-0529433GO:2000819
GeneOntologyBiologicalProcessnucleotide-excision repair

SMARCA2 SMARCD2 ARID1A RNF111

3.36e-0588434GO:0006289
GeneOntologyBiologicalProcessregulation of G0 to G1 transition

SMARCA2 SMARCD2 ARID1A

9.15e-0542433GO:0070316
GeneOntologyBiologicalProcessregulation of T cell differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.04e-04226435GO:0045580
GeneOntologyBiologicalProcessG0 to G1 transition

SMARCA2 SMARCD2 ARID1A

1.05e-0444433GO:0045023
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.43e-04242435GO:1902107
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.43e-04242435GO:1903708
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion

SMARCA2 PTPN23 SMARCD2 ZMIZ1 ARID1A EP300

1.46e-04389436GO:0022409
GeneOntologyBiologicalProcessandrogen receptor signaling pathway

ZMIZ1 ARID1A EP300

1.64e-0451433GO:0030521
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

BAG4 SMARCA2 PTPN23 SMARCD2 ZMIZ1 ARID1A EP300

1.77e-04579437GO:0045785
GeneOntologyBiologicalProcesspositive regulation of myoblast differentiation

SMARCA2 SMARCD2 ARID1A

1.94e-0454433GO:0045663
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

2.22e-04266435GO:0045619
GeneOntologyBiologicalProcesspositive regulation of DNA repair

FAM168A SMARCA2 SMARCD2 ARID1A

2.22e-04143434GO:0045739
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

ZMIZ1 ARID1A EP300 RXRG

3.01e-04155434GO:0043401
GeneOntologyBiologicalProcesspositive regulation of T cell activation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

3.30e-04290435GO:0050870
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

TCF4 NACC2 TLE2 YLPM1 SMARCA2 SOX18 ARID1A TCF7L1 EP300 NR2F1

4.85e-0413994310GO:0045892
GeneOntologyBiologicalProcesspositive regulation of leukocyte cell-cell adhesion

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

4.95e-04317435GO:1903039
GeneOntologyBiologicalProcesschordate embryonic development

SHROOM3 CELF4 SEC24C SOX18 ZMIZ1 SSBP3 ARID1A EP300

4.96e-04906438GO:0043009
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

TCF4 NACC2 TLE2 YLPM1 SMARCA2 SOX18 ARID1A TCF7L1 EP300 NR2F1

5.25e-0414134310GO:1902679
GeneOntologyBiologicalProcesshead development

ERBB4 NAV2 ZMIZ1 SSBP3 ARID1A EP300 NR2F1 MEIS1

5.45e-04919438GO:0060322
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

SMARCA2 ARID1A TCF7L1

5.76e-0478433GO:2000036
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

SHROOM3 CELF4 SEC24C SOX18 ZMIZ1 SSBP3 ARID1A EP300

5.85e-04929438GO:0009792
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

ZMIZ1 ARID1A EP300 RXRG

8.17e-04202434GO:0141193
GeneOntologyBiologicalProcessregulation of hemopoiesis

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300 MEIS1

8.38e-04540436GO:1903706
GeneOntologyBiologicalProcessheart development

ERBB4 SOX18 ZMIZ1 ARID1A RBM20 EP300 MEIS1

8.88e-04757437GO:0007507
GeneOntologyBiologicalProcessembryonic pattern specification

ERBB4 TCF7L1 MEIS1

9.02e-0491433GO:0009880
GeneOntologyBiologicalProcessregulation of myoblast differentiation

SMARCA2 SMARCD2 ARID1A

9.31e-0492433GO:0045661
GeneOntologyBiologicalProcessnucleosome disassembly

SMARCD2 ARID1A

9.55e-0422432GO:0006337
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

SMARCA2 SMARCD2 ARID1A

1.02e-0395433GO:0030071
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

SMARCA2 SMARCD2 ARID1A

1.02e-0395433GO:2000781
GeneOntologyBiologicalProcessanimal organ morphogenesis

AMBN ERBB4 TLE2 SOX18 ZMIZ1 ARID1A RBM20 EP300 MEIS1

1.03e-031269439GO:0009887
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

SMARCA2 SMARCD2 ARID1A

1.12e-0398433GO:1902099
GeneOntologyBiologicalProcessprotein-DNA complex disassembly

SMARCD2 ARID1A

1.14e-0324432GO:0032986
GeneOntologyBiologicalProcesscardiocyte differentiation

SOX18 ARID1A EP300 MEIS1

1.14e-03221434GO:0035051
GeneOntologyBiologicalProcessT cell differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.15e-03382435GO:0030217
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

SMARCA2 SMARCD2 ARID1A

1.19e-03100433GO:0007091
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.19e-03385435GO:0051251
GeneOntologyBiologicalProcessregulation of cell-cell adhesion

SMARCA2 PTPN23 SMARCD2 ZMIZ1 ARID1A EP300

1.21e-03580436GO:0022407
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

SMARCA2 SMARCD2 ARID1A

1.29e-03103433GO:0044784
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

TCF4 NACC2 YLPM1 SMARCA2 SOX18 ARID1A EP300 NR2F1

1.32e-031053438GO:0000122
GeneOntologyBiologicalProcessmegakaryocyte development

EP300 MEIS1

1.34e-0326432GO:0035855
GeneOntologyBiologicalProcessregulation of DNA repair

FAM168A SMARCA2 SMARCD2 ARID1A

1.41e-03234434GO:0006282
GeneOntologyBiologicalProcessregulation of cellular response to stress

FAM168A NACC2 SMARCA2 SMARCD2 ARID1A EP300

1.42e-03598436GO:0080135
GeneOntologyBiologicalProcesslate endosome to vacuole transport via multivesicular body sorting pathway

PTPN23 VTA1

1.44e-0327432GO:0032511
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

ZMIZ1 ARID1A EP300 RXRG

1.52e-03239434GO:0071383
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

CELF4 RBM20

1.55e-0328432GO:0048025
GeneOntologyBiologicalProcessregulation of sister chromatid segregation

SMARCA2 SMARCD2 ARID1A

1.60e-03111433GO:0033045
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

ZMIZ1 ARID1A EP300 RXRG

1.64e-03244434GO:0009755
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

CELF4 RBM20

1.66e-0329432GO:0050686
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

ZMIZ1 ARID1A EP300 NR2F1 RXRG

1.67e-03416435GO:0030522
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

CELF4 BAG4 RBM20

1.77e-03115433GO:1903312
GeneOntologyBiologicalProcesspositive regulation of leukocyte activation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.80e-03423435GO:0002696
GeneOntologyBiologicalProcessbrain development

ERBB4 NAV2 ZMIZ1 SSBP3 ARID1A NR2F1 MEIS1

1.84e-03859437GO:0007420
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.91e-03429435GO:1902105
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

CELF4 RBM20

2.15e-0333432GO:0033119
GeneOntologyBiologicalProcessregulation of chromosome organization

YLPM1 SMARCA2 SMARCD2 ARID1A

2.25e-03266434GO:0033044
GeneOntologyBiologicalProcessregulation of leukocyte cell-cell adhesion

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

2.28e-03447435GO:1903037
GeneOntologyBiologicalProcesspositive regulation of cell activation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

2.33e-03449435GO:0050867
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

EP300 RNF111

2.42e-0335432GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

EP300 RNF111

2.42e-0335432GO:0030511
GeneOntologyBiologicalProcesscirculatory system development

TCF4 ERBB4 SMARCA2 SOX18 ZMIZ1 ARID1A RBM20 EP300 MEIS1

2.51e-031442439GO:0072359
GeneOntologyBiologicalProcessregulation of T cell activation

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

2.54e-03458435GO:0050863
GeneOntologyCellularComponentbBAF complex

SMARCA2 SMARCD2 ARID1A

9.63e-0710433GO:0140092
GeneOntologyCellularComponentbrahma complex

SMARCA2 SMARCD2 ARID1A

2.90e-0614433GO:0035060
GeneOntologyCellularComponenttranscription regulator complex

TCF4 TLE2 SOX18 SSBP3 TCF7L1 EP300 RXRG MEIS1

2.50e-05596438GO:0005667
GeneOntologyCellularComponentSWI/SNF complex

SMARCA2 SMARCD2 ARID1A

3.17e-0530433GO:0016514
GeneOntologyCellularComponentchromatin

TCF4 NACC2 SMARCA2 SOX18 SMARCD2 ZMIZ1 ARID1A TCF7L1 EP300 RXRG MEIS1

1.50e-0414804311GO:0000785
GeneOntologyCellularComponentbeta-catenin-TCF complex

TCF4 TCF7L1

3.18e-0413432GO:1990907
GeneOntologyCellularComponentnpBAF complex

SMARCA2 ARID1A

3.70e-0414432GO:0071564
GeneOntologyCellularComponentnBAF complex

SMARCA2 ARID1A

4.87e-0416432GO:0071565
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCA2 SMARCD2 ARID1A

1.01e-0396433GO:0070603
GeneOntologyCellularComponentinhibitory synapse

ERBB4 PCLO

1.85e-0331432GO:0060077
GeneOntologyCellularComponentATPase complex

SMARCA2 SMARCD2 ARID1A

2.37e-03129433GO:1904949
GeneOntologyCellularComponentendoplasmic reticulum exit site

SEC24C TFG

3.38e-0342432GO:0070971
MousePhenoabsent myocardial trabeculae

ERBB4 ARID1A EP300

2.14e-0522353MP:0000293
MousePhenoembryonic lethality during organogenesis

ERBB4 UBR4 PTPN23 ZMIZ1 SSBP3 ARID1A TCF7L1 EP300 MEIS1 RNF111

3.86e-058763510MP:0006207
MousePhenoembryonic lethality during organogenesis, complete penetrance

ERBB4 UBR4 PTPN23 ZMIZ1 ARID1A TCF7L1 EP300 MEIS1 RNF111

4.10e-05700359MP:0011098
MousePhenoperinatal lethality, complete penetrance

TCF4 SHROOM3 FUBP1 UBR4 SOX18 ARID1A TCF7L1 EP300 NR2F1

4.68e-05712359MP:0011089
MousePhenoperinatal lethality

TCF4 SHROOM3 CELF4 COL12A1 FUBP1 UBR4 SOX18 ARID1A TCF7L1 EP300 NR2F1

6.23e-0511303511MP:0002081
MousePhenoabnormal prenatal growth/weight/body size

CDK8 CELF4 FUBP1 UBR4 YLPM1 PTPN23 ZMIZ1 SSBP3 ARID1A TCF7L1 EP300 NR2F1

1.68e-0414933512MP:0004196
MousePhenodecreased hippocampus volume

TCF4 NR2F1

3.30e-0411352MP:0020083
MousePhenoabnormal embryo development

CDK8 SHROOM3 UBR4 YLPM1 PTPN23 SSBP3 ARID1A TCF7L1 EP300 NR2F1 RNF111

3.49e-0413703511MP:0001672
MousePhenoabsent trabeculae carneae

ERBB4 EP300

4.67e-0413352MP:0000296
MousePhenothin placenta labyrinth

FUBP1 UBR4

5.44e-0414352MP:0011523
MousePhenodecreased thigmotaxis

FAM168A FUBP1 NAV2 MPLKIP SOX18

5.69e-04275355MP:0020870
MousePhenoneonatal lethality

TCF4 CELF4 FUBP1 UBR4 SOX18 ARID1A TCF7L1 NR2F1

6.51e-04799358MP:0002058
MousePhenoabnormal cardiovascular development

ERBB4 SHROOM3 CELF4 UBR4 ZMIZ1 ARID1A EP300 MEIS1

6.67e-04802358MP:0002925
MousePhenoabnormal nervous system development

CDK8 TCF4 ERBB4 SHROOM3 SSBP3 ARID1A TCF7L1 EP300 NR2F1 RNF111

7.55e-0412573510MP:0003861
MousePhenodecreased brain size

TCF4 MPLKIP SSBP3 ARID1A TCF7L1

7.81e-04295355MP:0000774
MousePhenodecreased anxiety-related response

TCF4 FAM168A FUBP1 NAV2 MPLKIP SOX18

8.09e-04452356MP:0001364
MousePhenolethality during fetal growth through weaning, complete penetrance

TCF4 SHROOM3 FUBP1 UBR4 SOX18 ARID1A TCF7L1 EP300 NR2F1 MEIS1

8.13e-0412693510MP:0011111
MousePhenoabnormal blood circulation

ERBB4 FUBP1 SOX18 ARID1A TCF7L1 RBM20 EP300 MEIS1

9.41e-04845358MP:0002128
MousePhenoabnormal embryonic growth/weight/body size

CDK8 UBR4 YLPM1 PTPN23 ZMIZ1 SSBP3 ARID1A TCF7L1 EP300 NR2F1

9.53e-0412953510MP:0002088
DomainSSDP_DNA-bd

SSBP4 SSBP3

1.48e-053422IPR008116
DomainBromodomain_CS

SMARCA2 EP300

1.55e-0326422IPR018359
DomainLisH

SSBP4 SSBP3

1.80e-0328422IPR006594
DomainLisH

SSBP4 SSBP3

1.80e-0328422SM00667
DomainLISH

SSBP4 SSBP3

1.80e-0328422PS50896
DomainBROMODOMAIN_1

SMARCA2 EP300

3.13e-0337422PS00633
DomainBromodomain

SMARCA2 EP300

3.30e-0338422PF00439
DomainBROMODOMAIN_2

SMARCA2 EP300

3.83e-0341422PS50014
DomainBROMO

SMARCA2 EP300

4.02e-0342422SM00297
DomainBromodomain

SMARCA2 EP300

4.02e-0342422IPR001487
Domain-

SMARCA2 EP300

4.02e-03424221.20.920.10
Domainzf-C4

NR2F1 RXRG

4.80e-0346422PF00105
DomainNUCLEAR_REC_DBD_1

NR2F1 RXRG

4.80e-0346422PS00031
DomainZnf_hrmn_rcpt

NR2F1 RXRG

4.80e-0346422IPR001628
DomainNuclear_hrmn_rcpt

NR2F1 RXRG

4.80e-0346422IPR001723
DomainZnF_C4

NR2F1 RXRG

4.80e-0346422SM00399
DomainNUCLEAR_REC_DBD_2

NR2F1 RXRG

4.80e-0346422PS51030
Domain-

NR2F1 RXRG

5.01e-03474221.10.565.10
DomainHOLI

NR2F1 RXRG

5.22e-0348422SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR2F1 RXRG

5.22e-0348422IPR000536
DomainHormone_recep

NR2F1 RXRG

5.22e-0348422PF00104
DomainHMG_box

SOX18 TCF7L1

6.33e-0353422PF00505
DomainHMG_BOX_2

SOX18 TCF7L1

6.56e-0354422PS50118
DomainHMG

SOX18 TCF7L1

6.56e-0354422SM00398
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

SMARCA2 SMARCD2 ARID1A EP300

7.86e-0737284M27797
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE2 TCF7L1 EP300

1.77e-0526283MM14793
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TCF4 TLE2 TCF7L1 EP300

1.78e-0580284M223
PathwayWP_KLEEFSTRA_SYNDROME

SMARCA2 SMARCD2 ARID1A

2.48e-0529283M48076
PathwayKEGG_THYROID_CANCER

TFG TCF7L1 RXRG

2.48e-0529283M523
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF4 TLE2 TCF7L1 EP300

2.95e-0591284M27101
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

SMARCA2 SMARCD2 ARID1A TCF7L1

3.50e-0595284M48268
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

SMARCD2 ARID1A EP300

4.03e-0534283MM15531
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

SMARCA2 SMARCD2 ARID1A

4.40e-0535283M47969
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CDK8 EP300 RNF111

4.80e-0536283M633
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

SMARCA2 SMARCD2 ARID1A

7.65e-0542283M48237
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

CDK8 SMARCD2 ARID1A TCF7L1 EP300 NR2F1 RXRG RNF111

8.77e-05768288MM14851
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CDK8 TLE2 EP300

1.14e-0448283M611
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CDK8 EP300 RNF111

1.37e-0451283M665
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

SMARCA2 SMARCD2 ARID1A TCF7L1

1.46e-04137284M48232
PathwayPID_AR_TF_PATHWAY

SMARCA2 EP300 RXRG

1.54e-0453283M151
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE2 TCF7L1

1.70e-0410282MM15156
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

CDK8 TCF4 EP300 RNF111

2.71e-04161284M27871
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

TLE2 SMARCA2 TCF7L1 EP300 NR2F1

2.82e-04301285MM15983
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

SMARCA2 ARID1A EP300

2.82e-0465283M39682
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE2 TCF7L1

3.41e-0414282M27402
PathwayREACTOME_SIGNALING_BY_NOTCH1

CDK8 TLE2 EP300

4.14e-0474283M616
PathwayREACTOME_RMTS_METHYLATE_HISTONE_ARGININES

SMARCA2 SMARCD2 ARID1A

4.83e-0478283M27234
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

CDK8 SMARCD2 ARID1A TCF7L1 EP300 NR2F1 RXRG RNF111

6.23e-041022288MM15436
PathwayWNT_SIGNALING

TLE2 TCF7L1 EP300

7.11e-0489283M5493
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

CDK8 EP300 RNF111

8.34e-0494283M1041
PathwayBIOCARTA_VDR_PATHWAY

ARID1A EP300

8.57e-0422282MM1370
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

SMARCA2 SMARCD2 ARID1A

9.13e-0497283M48262
PathwayBIOCARTA_HER2_PATHWAY

ERBB4 EP300

9.38e-0423282MM1480
PathwayBIOCARTA_HER2_PATHWAY

ERBB4 EP300

9.38e-0423282M18719
PathwayBIOCARTA_VDR_PATHWAY

ARID1A EP300

1.02e-0324282M13404
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

TCF4 TCF7L1 EP300

1.03e-03101283MM15829
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

CDK8 SMARCA2 SMARCD2 ARID1A TCF7L1 EP300 NR2F1 RXRG RNF111

1.03e-031387289M734
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

TCF4 TLE2 TCF7L1 EP300

1.09e-03233284M27099
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

SMARCA2 SMARCD2 ARID1A EP300

1.16e-03237284M27786
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CDK8 RNF111

1.20e-0326282MM14878
PathwayWP_THERMOGENESIS

SMARCA2 SMARCD2 ARID1A

1.25e-03108283M39746
PathwayREACTOME_TGFBR3_EXPRESSION

TCF4 EP300

1.39e-0328282M48253
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SMARCA2 SMARCD2 ARID1A EP300

1.50e-03254284M27131
PathwayPID_RETINOIC_ACID_PATHWAY

EP300 RXRG

1.60e-0330282M207
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

SMARCD2 ARID1A

1.71e-0331282M39522
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE2 TCF7L1

1.82e-0332282MM14975
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

SMARCA2 SMARCD2 ARID1A EP300

1.93e-03272284M29619
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4

ERBB4 ATP2C2

1.93e-0333282M39455
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

CDK8 ERBB4 BAG4 TFG EP300

1.99e-03464285M27547
PathwayWP_NUCLEAR_RECEPTORS

NR2F1 RXRG

2.56e-0338282M39657
PathwayWP_NUCLEAR_RECEPTORS

NR2F1 RXRG

2.56e-0338282MM15865
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

SMARCA2 SMARCD2 ARID1A

2.73e-03142283M48257
PathwayREACTOME_RMTS_METHYLATE_HISTONE_ARGININES

SMARCD2 ARID1A

2.83e-0340282MM14936
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CDK8 RNF111

2.97e-0341282MM14876
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE2 TCF7L1

3.12e-0342282M27272
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

TCF4 TCF7L1 MEIS1

3.37e-03153283M39546
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

SMARCD2 ARID1A EP300

3.37e-03153283MM15522
PathwayKEGG_PATHWAYS_IN_CANCER

TFG TCF7L1 EP300 RXRG

3.67e-03325284M12868
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

TLE2 TCF7L1 EP300

3.68e-03158283MM14791
PathwayREACTOME_SIGNALING_BY_WNT

TCF4 TLE2 TCF7L1 EP300

3.87e-03330284M7847
PathwayWP_RETT_SYNDROME

TCF4 SMARCA2

4.06e-0348282M39759
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR2F1 RXRG

4.06e-0348282MM14987
PathwayREACTOME_SIGNALING_BY_TGFBR3

TCF4 EP300

4.22e-0349282M48250
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR2F1 RXRG

4.92e-0353282M8276
Pubmed

Human transcription factor protein interaction networks.

TCF4 SMG7 FUBP1 UBR4 YLPM1 SMARCA2 SMARCD2 R3HDM2 ZMIZ1 SSBP4 SSBP3 ARID1A RBM20 EP300

6.42e-091429491435140242
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

SMG7 FUBP1 YLPM1 SMARCA2 ZMIZ1 ARID1A TFG RBM20 EP300

1.39e-0845749932344865
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TCF4 SMARCA2 SOX18 SMARCD2 ARID1A TCF7L1 NR2F1 RXRG MEIS1 RNF111

4.67e-08709491022988430
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

SMARCA2 SMARCD2 ARID1A EP300

3.06e-074049434585037
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

FUBP1 YLPM1 SMARCA2 SMARCD2 ARID1A EP300

6.67e-0722049635785414
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

SEC24C SMARCA2 ARID1A TFG

7.63e-075049427716508
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDK8 SHROOM3 SMG7 FAM168A NACC2 JOSD2 FUBP1 SMARCA2 ZMIZ1 SSBP3 ARID1A EP300

7.68e-071489491228611215
Pubmed

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

SMARCA2 SMARCD2 ARID1A

9.46e-07144938895581
Pubmed

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

SMARCA2 SMARCD2 ARID1A EP300

1.12e-065549435945219
Pubmed

Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.

TCF4 ERBB4 NR2F1 RXRG MEIS1

1.13e-0613049519386638
Pubmed

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

FUBP1 SMARCA2 SMARCD2 ARID1A EP300

1.17e-0613149534551306
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

SMARCA2 SMARCD2 ARID1A

1.18e-061549311263494
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

SMARCA2 SMARCD2 ARID1A

1.18e-061549311175787
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

SMARCA2 SMARCD2 ARID1A

1.18e-061549317920018
Pubmed

Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.

TCF4 ERBB4 NR2F1 RXRG MEIS1

1.31e-0613449519030180
Pubmed

A human RNA polymerase II complex containing factors that modify chromatin structure.

CDK8 SMARCA2 EP300

1.45e-06164939710619
Pubmed

Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.

SMARCA2 SMARCD2 ARID1A

1.45e-061649335390516
Pubmed

Widespread macromolecular interaction perturbations in human genetic disorders.

TCF4 PRR20E ANXA11 SMARCA2 NAV2 PRR20A TFG RXRG

1.60e-0659049825910212
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

SMARCA2 SMARCD2 ARID1A

1.76e-061749312368262
Pubmed

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

SMARCA2 SMARCD2 ARID1A

1.76e-061749311078522
Pubmed

Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.

SMARCA2 ARID1A

1.94e-06249211318604
Pubmed

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.

SMARCA2 SMARCD2 ARID1A

2.11e-061849314559996
Pubmed

TIF1gamma controls erythroid cell fate by regulating transcription elongation.

TCF4 SSBP4 SSBP3

2.11e-061849320603019
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

SMARCA2 ARID1A EP300

2.11e-061849328068325
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

SMARCA2 SMARCD2 ARID1A

2.11e-061849323698369
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

TCF4 R3HDM2 ZMIZ1 SSBP3 EP300

2.44e-0615249538360978
Pubmed

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.

SMARCA2 SMARCD2 ARID1A

2.51e-061949316932743
Pubmed

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

SMARCA2 SMARCD2 ARID1A

2.51e-061949312110891
Pubmed

A protein interaction landscape of breast cancer.

SEC24C FUBP1 ANXA11 UBR4 SMARCA2 NAV2 SMARCD2 ARID1A

2.72e-0663449834591612
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CDK8 AMBN ERBB4 SMG7 BAG4 SMARCA2 SMARCD2 ARID1A TCF7L1 EP300

2.93e-061116491031753913
Pubmed

Molecular evolution of Sry and Sox gene.

TCF4 SOX18 TCF7L1

2.95e-062049311404013
Pubmed

The DNA sequence and analysis of human chromosome 13.

PRR20C PRR20D PRR20B PRR20E PRR20A

4.21e-0617049515057823
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

SMARCA2 SMARCD2 ARID1A

4.56e-062349330962207
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

SMARCA2 SMARCD2 ARID1A

4.56e-06234938804307
Pubmed

SWI/SNF chromatin remodeling and cancer.

SMARCA2 SMARCD2 ARID1A

5.21e-062449311790558
Pubmed

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

SMARCA2 SMARCD2 ARID1A

5.21e-062449310078207
Pubmed

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

SMARCA2 SMARCD2 ARID1A

5.21e-062449312215535
Pubmed

Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.

SMARCA2 ARID1A

5.83e-06349236464671
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

TCF4 EP300

5.83e-06349217410209
Pubmed

A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.

SSBP4 SSBP3

5.83e-06349212079286
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SEC24C ANXA11 UBR4 SMARCA2 PTPN23 SMARCD2 VTA1 SSBP3

5.87e-0670449829955894
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

SMARCA2 SMARCD2 ARID1A

6.68e-062649310778858
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

SMARCA2 SMARCD2 ARID1A

7.51e-062749329374058
Pubmed

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.

BAG4 SMARCA2 SMARCD2 TFG

8.13e-069049433087562
Pubmed

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

SMARCD2 ARID1A TFG

8.40e-062849330037996
Pubmed

REST repression of neuronal genes requires components of the hSWI.SNF complex.

SMARCA2 SMARCD2 ARID1A

8.40e-062849312192000
Pubmed

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.

SMARCA2 SSBP3 TCF7L1 NR2F1

8.49e-069149421194568
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

TCF4 SSBP4 SSBP3

1.04e-053049326593974
Pubmed

Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.

SMARCA2 ARID1A

1.16e-05449231906887
Pubmed

Constitutional and functional genetics of human alcohol-related hepatocellular carcinoma.

SMARCA2 ARID1A

1.16e-05449228296015
Pubmed

C-terminal α Domain of p63 Binds to p300 to Coactivate β-Catenin.

TCF4 EP300

1.16e-05449230986748
Pubmed

ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation.

ARID1A EP300

1.16e-05449233176148
Pubmed

The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.

SMARCA2 ARID1A

1.16e-05449233481850
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SHROOM3 SEC24C FUBP1 ANXA11 YLPM1 SMARCA2 ARID1A

1.66e-0558249720467437
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

SMARCA2 SMARCD2 ARID1A

1.67e-053549332504627
Pubmed

Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.

SMARCA2 EP300

1.94e-05549218487222
Pubmed

Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.

SMARCA2 ARID1A

1.94e-05549212200431
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TCF4 PCLO UBR4 ZMIZ1 SSBP3 TCF7L1

1.94e-0539649626687479
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

SMARCA2 SMARCD2 ARID1A

1.97e-053749324335282
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

PCLO SMARCA2 SMARCD2 ARID1A RBM20 EP300

2.00e-0539849635016035
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

YLPM1 SMARCA2 SMARCD2 ARID1A EP300 MEIS1

2.39e-0541149635182466
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

SEC24C FAM168A PCLO ARID1A TFG EP300

2.88e-0542549624999758
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

SMARCA2 ARID1A

2.91e-05649216940996
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

SMARCA2 ARID1A

2.91e-05649216230384
Pubmed

Numerous BAF complex genes are mutated in Coffin-Siris syndrome.

SMARCA2 ARID1A

2.91e-05649225081545
Pubmed

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.

NR2F1 RXRG

2.91e-0564927947324
Pubmed

Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis.

TCF4 EP300

2.91e-05649226123998
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

SOX18 TCF7L1 NR2F1 RXRG MEIS1

3.46e-0526349520932939
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CDK8 YLPM1 SMARCA2 SMARCD2 ARID1A

3.78e-0526849533640491
Pubmed

Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter.

SMARCA2 EP300

4.07e-05749216601680
Pubmed

A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes.

SMARCA2 EP300

4.07e-05749221079652
Pubmed

Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo.

TCF4 TCF7L1

4.07e-05749219303461
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

CDK8 FUBP1 ANXA11 SMARCD2 ARID1A EP300

4.11e-0545349629656893
Pubmed

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.

EP300 RXRG

5.42e-05849212082103
Pubmed

Connective tissue fibroblasts and Tcf4 regulate myogenesis.

TCF4 TCF7L1

5.42e-05849221177349
Pubmed

TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.

TCF4 TCF7L1

5.42e-05849232179550
Pubmed

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.

SMARCA2 ARID1A

5.42e-05849226986003
Pubmed

Discovery of genes required for body axis and limb formation by global identification of retinoic acid-regulated epigenetic marks.

NR2F1 MEIS1

5.42e-05849232421711
Pubmed

A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.

NR2F1 RXRG

6.96e-0594927823919
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SMARCA2 SMARCD2 ARID1A EP300

7.23e-0515749430186101
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

TCF4 FAM168A PRR20E NAV2 PRR20A TFG RNF111

7.71e-0574249726871637
Pubmed

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

SMARCD2 ARID1A

8.69e-051049212665591
Pubmed

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.

CDK8 EP300

8.69e-051049223746844
Pubmed

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.

SMARCA2 ARID1A

8.69e-051049223129809
Pubmed

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis.

ARID1A EP300

8.69e-051049235210568
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

SMARCA2 SMARCD2 ARID1A

8.93e-056149320305087
Pubmed

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.

CDK8 EP300

1.06e-041149215546612
Pubmed

Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities.

SSBP4 SSBP3

1.06e-041149226965372
Pubmed

Targeting HIV transcription: the quest for a functional cure.

SMARCA2 EP300

1.06e-041149225731772
Pubmed

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator.

CDK8 EP300

1.06e-041149215808511
Pubmed

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

TCF4 SMARCA2 ZMIZ1

1.08e-046549323453885
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

SMARCA2 SMARCD2 ARID1A

1.08e-046549326655900
Pubmed

Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.

SMARCA2 SSBP3 EP300

1.13e-046649323275444
Pubmed

Genome-scale study of transcription factor expression in the branching mouse lung.

SOX18 NR2F1 MEIS1

1.18e-046749322711520
Pubmed

TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function.

TCF4 TCF7L1

1.27e-041249221938009
Pubmed

Amelogenesis imperfecta in a new animal model--a mutation in chromosome 5 (human 4q21).

AMBN SHROOM3

1.27e-041249215271968
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

SMARCA2 ARID1A

1.27e-041249211734557
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TLE2 TCF7L1

1.27e-041249211266540
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

TCF4 SMARCA2 SMARCD2 ARID1A TCF7L1 NR2F1 MEIS1

1.31e-0480849720412781
Pubmed

Interaction network of human early embryonic transcription factors.

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

1.35e-0435149538297188
InteractionCELF4 interactions

PRR20C PRR20D CELF4 PRR20B PRR20E PRR20A

5.29e-1411476int:CELF4
InteractionZNF683 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.38e-1110475int:ZNF683
InteractionPRR20B interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A TFG

3.14e-1190478int:PRR20B
InteractionPRR20C interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A TFG

3.14e-1190478int:PRR20C
InteractionPRR20D interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A TFG

3.14e-1190478int:PRR20D
InteractionVPS37C interactions

PRR20C PRR20D PRR20B FAM168A PRR20E FUBP1 BAG4 PRR20A TFG

3.38e-11141479int:VPS37C
InteractionFAM168A interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A SMARCD2 R3HDM2 TFG

3.60e-11142479int:FAM168A
InteractionBEND2 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.33e-1112475int:BEND2
InteractionTLX3 interactions

PRR20C PRR20D PRR20B PRR20E TLE2 SMARCA2 PRR20A SSBP3 ARID1A EP300 MEIS1

5.17e-112914711int:TLX3
InteractionPRR20E interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A TFG

8.03e-11101478int:PRR20E
InteractionPTTG2 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.09e-1014475int:PTTG2
InteractionPRR20A interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A TFG

1.49e-10109478int:PRR20A
InteractionLASP1 interactions

TCF4 PRR20C PRR20D PRR20B FAM168A PRR20E BAG4 PRR20A TFG EP300

2.22e-102474710int:LASP1
InteractionMBNL3 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

2.37e-1016475int:MBNL3
InteractionHLX interactions

PRR20C PRR20D PRR20B PRR20E TLE2 PRR20A

2.54e-1037476int:HLX
InteractionFAM222B interactions

PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A

5.69e-1042476int:FAM222B
InteractionBICRAL interactions

PRR20C PRR20D PRR20B PRR20E SMARCA2 PRR20A

6.60e-1043476int:BICRAL
InteractionRBPMS2 interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E PRR20A

8.55e-1083477int:RBPMS2
InteractionPRR34 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.10e-0921475int:PRR34
InteractionTPRX1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.10e-0921475int:TPRX1
InteractionKRTAP19-1 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

1.15e-0947476int:KRTAP19-1
InteractionOXER1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A TFG

1.70e-0950476int:OXER1
InteractionSS18L1 interactions

FAM168A BAG4 SMARCA2 SMARCD2 SSBP3 ARID1A EP300

2.78e-0998477int:SS18L1
InteractionRIPPLY1 interactions

PRR20C PRR20D PRR20B PRR20E TLE2 PRR20A

3.07e-0955476int:RIPPLY1
InteractionC3orf36 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

3.51e-0926475int:C3orf36
InteractionC1orf94 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A R3HDM2

3.94e-09103477int:C1orf94
InteractionTIAL1 interactions

PRR20C PRR20D CELF4 PRR20B FAM168A PRR20E FUBP1 PRR20A

5.66e-09172478int:TIAL1
InteractionFOXH1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A TFG RXRG

5.86e-09109477int:FOXH1
InteractionTFG interactions

PRR20C PRR20D PRR20B FAM168A PRR20E ANXA11 PRR20A R3HDM2 TFG

7.16e-09258479int:TFG
InteractionC10orf55 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

8.61e-0965476int:C10orf55
InteractionDAZAP2 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A TFG TCF7L1

1.05e-08186478int:DAZAP2
InteractionTBX3 interactions

CDK8 PRR20C PRR20D PRR20B PRR20E PRR20A

1.24e-0869476int:TBX3
InteractionZNF385C interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.25e-0833475int:ZNF385C
InteractionPITX1 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E SMARCA2 PRR20A

1.70e-08127477int:PITX1
InteractionZCCHC14 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

2.28e-0837475int:ZCCHC14
InteractionMAGED1 interactions

PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A R3HDM2 TFG EP300

2.29e-08295479int:MAGED1
InteractionESRP1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A RNF111

2.42e-0877476int:ESRP1
InteractionNR4A1 interactions

TCF4 BAG4 SMARCA2 SMARCD2 TFG EP300 RXRG RNF111

2.90e-08212478int:NR4A1
InteractionSP7 interactions

FUBP1 YLPM1 SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A RBM20 EP300

2.96e-08304479int:SP7
InteractionTBX6 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

3.90e-0841475int:TBX6
InteractionFOXP3 interactions

PRR20C PRR20D PRR20B SEC24C NACC2 PRR20E PRR20A SSBP3 ARID1A EP300

4.71e-084324710int:FOXP3
InteractionSAMD11 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.99e-0843475int:SAMD11
InteractionDMRT3 interactions

TCF4 PRR20C PRR20D PRR20B PRR20E PRR20A

5.06e-0887476int:DMRT3
InteractionSP4 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

7.07e-0846475int:SP4
InteractionRBPMS interactions

PRR20C PRR20D PRR20B FAM168A PRR20E BAG4 PRR20A R3HDM2 TFG

7.72e-08340479int:RBPMS
InteractionRBM23 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A EP300

8.06e-0894476int:RBM23
InteractionSMARCC2 interactions

CDK8 TCF4 FUBP1 YLPM1 SMARCA2 SMARCD2 SSBP3 ARID1A EP300

1.06e-07353479int:SMARCC2
InteractionKRTAP19-5 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

1.10e-0799476int:KRTAP19-5
InteractionTOLLIP interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A PTPN23 VTA1 TFG

1.20e-07358479int:TOLLIP
InteractionRHOXF2 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

1.48e-07104476int:RHOXF2
InteractionVENTX interactions

PRR20C PRR20D PRR20B PRR20E TLE2 PRR20A

1.48e-07104476int:VENTX
InteractionNCK2 interactions

TCF4 ERBB4 PRR20C PRR20D PRR20B PRR20E YLPM1 PRR20A

1.49e-07262478int:NCK2
InteractionSH3RF1 interactions

PRR20C SHROOM3 PRR20D PRR20B PRR20E PRR20A

1.85e-07108476int:SH3RF1
InteractionZBTB32 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

2.32e-0758475int:ZBTB32
InteractionHIVEP1 interactions

CDK8 PRR20C PRR20D PRR20B SMG7 PRR20E PRR20A

2.35e-07186477int:HIVEP1
InteractionTBR1 interactions

SMARCA2 SMARCD2 ZMIZ1 SSBP3 ARID1A EP300

2.42e-07113476int:TBR1
InteractionFAM9A interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

2.53e-0759475int:FAM9A
InteractionCABP2 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

2.99e-0761475int:CABP2
InteractionETS1 interactions

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300 MEIS1

3.63e-07121476int:ETS1
InteractionEIF4ENIF1 interactions

PRR20C PRR20D PRR20B SMG7 PRR20E BAG4 PRR20A R3HDM2

4.17e-07300478int:EIF4ENIF1
InteractionPAX7 interactions

SMARCA2 SMARCD2 SSBP4 SSBP3 ARID1A EP300

4.20e-07124476int:PAX7
InteractionPDCD6 interactions

FUBP1 ANXA11 BAG4 SMARCA2 PTPN23 ARID1A TFG

4.38e-07204477int:PDCD6
InteractionSMAP1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.80e-0767475int:SMAP1
InteractionNUP35 interactions

SMG7 FUBP1 YLPM1 SMARCA2 ZMIZ1 ARID1A TFG RBM20 EP300

4.98e-07424479int:NUP35
InteractionETV4 interactions

SMARCA2 SMARCD2 ZMIZ1 ARID1A EP300

5.57e-0769475int:ETV4
InteractionSNRPC interactions

PRR20C PRR20D PRR20B FAM168A PRR20E FUBP1 BAG4 YLPM1 PRR20A

6.78e-07440479int:SNRPC
InteractionARID5A interactions

PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A

1.14e-06147476int:ARID5A
InteractionSOX7 interactions

SMARCA2 SMARCD2 ARID1A RBM20 EP300

1.32e-0682475int:SOX7
InteractionPRR35 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.40e-0683475int:PRR35
InteractionPATZ1 interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

2.08e-06163476int:PATZ1
InteractionTLE3 interactions

TCF4 SMG7 TLE2 ZMIZ1 SSBP4 ARID1A RBM20 EP300

2.27e-06376478int:TLE3
InteractionLHX4 interactions

TCF4 SMARCA2 SMARCD2 SSBP4 SSBP3 ARID1A

2.32e-06166476int:LHX4
InteractionDPF3 interactions

UBR4 SMARCA2 SMARCD2 ARID1A EP300

2.75e-0695475int:DPF3
InteractionTLX1 interactions

SMARCA2 SMARCD2 SSBP3 ARID1A EP300 MEIS1

3.14e-06175476int:TLX1
InteractionPOU2F1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A NR2F1

3.14e-06175476int:POU2F1
InteractionNFYC interactions

PRR20C PRR20D PRR20B FAM168A PRR20E PRR20A

3.36e-06177476int:NFYC
InteractionRARB interactions

CDK8 ARID1A EP300 RXRG

3.94e-0646474int:RARB
InteractionALG13 interactions

SMG7 BAG4 R3HDM2 ARID1A RBM20 EP300

4.07e-06183476int:ALG13
InteractionTCF7L2 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A TCF7L1 EP300

4.07e-06285477int:TCF7L2
InteractionLHX1 interactions

SMARCA2 SMARCD2 SSBP4 SSBP3 ARID1A

4.09e-06103475int:LHX1
InteractionTRIM35 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.09e-06103475int:TRIM35
InteractionABI2 interactions

TCF4 PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A

4.17e-06286477int:ABI2
InteractionGTF2A1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.29e-06104475int:GTF2A1
InteractionVEZF1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.50e-06105475int:VEZF1
InteractionGATA3 interactions

FUBP1 SMARCA2 SMARCD2 ARID1A RBM20 EP300

4.61e-06187476int:GATA3
InteractionGLIS2 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

4.71e-06106475int:GLIS2
InteractionPAX8 interactions

SMARCA2 SMARCD2 SSBP3 ARID1A EP300

5.91e-06111475int:PAX8
InteractionNOTCH3 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

6.45e-06113475int:NOTCH3
InteractionGATA2 interactions

SMARCA2 PRR20A SMARCD2 SSBP3 ARID1A EP300

6.59e-06199476int:GATA2
InteractionVAC14 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A EP300

6.98e-06201476int:VAC14
InteractionLHX8 interactions

SMARCA2 SMARCD2 SSBP4 SSBP3

6.99e-0653474int:LHX8
InteractionTBXT interactions

SMARCA2 SMARCD2 SSBP3 ARID1A EP300

7.33e-06116475int:TBXT
InteractionCIITA interactions

SMARCA2 SSBP4 SSBP3 EP300

8.12e-0655474int:CIITA
InteractionBHLHE40 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

8.30e-06119475int:BHLHE40
InteractionTHAP1 interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

8.30e-06119475int:THAP1
InteractionANKHD1 interactions

PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A

1.05e-05216476int:ANKHD1
InteractionHYPK interactions

PRR20C PRR20D PRR20B PRR20E PRR20A

1.05e-05125475int:HYPK
InteractionRBM42 interactions

PRR20C PRR20D PRR20B PRR20E BAG4 YLPM1 PRR20A

1.08e-05331477int:RBM42
InteractionERG interactions

UBR4 SMARCA2 SMARCD2 ARID1A EP300 RNF111

1.26e-05223476int:ERG
InteractionSIAH1 interactions

PRR20C PRR20D PRR20B PRR20E BAG4 PRR20A

1.26e-05223476int:SIAH1
Cytoband13q21.1

PRR20C PRR20D PRR20B PRR20E PRR20A

1.44e-121349513q21.1
CytobandEnsembl 112 genes in cytogenetic band chr13q21

PRR20C PRR20D PRR20B PRR20E PRR20A

1.72e-07117495chr13q21
CytobandEnsembl 112 genes in cytogenetic band chr10q22

SEC24C ANXA11 ZMIZ1

1.45e-03208493chr10q22
GeneFamilyNuclear hormone receptors

NR2F1 RXRG

2.60e-034928271
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

FUBP1 SMARCA2 NAV2 R3HDM2 ZMIZ1 ARID1A TCF7L1 RBM20 RXRG MEIS1

6.39e-0610094510M157
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL12A1 NAV2 SSBP3 NR2F1 MEIS1

1.40e-0618746576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

AMBN TCF4 ERBB4 TLE2 RXRG

1.52e-06190465842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 PCLO ATP2C2 TCF7L1

1.60e-0619246506013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 ATP2C2 NAV2 TCF7L1

1.60e-06192465efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

AMBN TCF4 ERBB4 CELF4 TLE2

1.77e-06196465556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 COL12A1 SMARCA2 NR2F1 MEIS1

1.81e-06197465ad6c200a193a15360d17463e18a465ce1b90b8da
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal|6_mon / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 CELF4 TLE2 PCLO

1.86e-06198465076c862f2a723f0361749377561cae902068b1a0
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 CELF4 PCLO NR2F1

1.95e-06200465bad32a95b759fad509401b07bc96a56687c2a592
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 CELF4 NR2F1

2.09e-06884645582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCF4 ERBB4 NACC2 MEIS1

1.52e-05145464590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellControl|World / group, cell type (main and fine annotations)

ERBB4 SHROOM3 ATP2C2 NAV2

2.71e-05168464a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

2.84e-05170464fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

2.84e-0517046403044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHROOM3 SMARCA2 SOX18 B3GALT5-AS1

2.84e-051704646c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 TCF7L1 MEIS1

2.97e-05172464553701349444eb366df3c11f54bb093434f153c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 TCF7L1 MEIS1

2.97e-0517246408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 RXRG MEIS1

3.18e-051754641b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 COL12A1 NACC2 RBM20

3.39e-05178464c982a73955c9c193bcab21d60d453afcc09cd586
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 RXRG MEIS1

3.62e-05181464a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 RXRG MEIS1

3.62e-05181464526e858a848470b6d2d5248788004d9735ed3add
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

3.70e-0518246444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

3.70e-05182464d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron|GW23 / Sample Type, Dataset, Time_group, and Cell type.

AMBN TCF4 ERBB4

3.80e-0563463c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

3.86e-05184464c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

3.86e-05184464e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ERBB4 PCLO ATP2C2 TCF7L1

4.20e-05188464ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATP2C2 NAV2 SSBP3 MEIS1

4.20e-05188464b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ERBB4 SHROOM3 ATP2C2 NAV2

4.20e-05188464c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

ERBB4 SHROOM3 NAV2 SSBP3

4.20e-05188464df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

TCF4 COL12A1 NR2F1 MEIS1

4.29e-0518946444e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.47e-0519146439092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 ATP2C2 NAV2

4.47e-05191464ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ERBB4 SHROOM3 PCLO ATP2C2

4.47e-05191464276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.47e-05191464ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 PCLO TCF7L1

4.56e-05192464cc9911e182a289779a2612bc213daae5607689e7
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 ATP2C2 NAV2

4.56e-05192464499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.56e-051924645105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 SHROOM3 PCLO BAG4

4.56e-0519246461c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 SHROOM3 PCLO BAG4

4.56e-05192464e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.65e-0519346409a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 ATP2C2 NAV2

4.65e-05193464a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TLE2 SOX18 TCF7L1 NR2F1

4.75e-05194464953578102ffc7b612ee8fce45e414750800fef5d
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

TCF4 ERBB4 CELF4 PCLO

4.75e-05194464b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

TCF4 ERBB4 CELF4 PCLO

4.75e-0519446481e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.75e-05194464e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.75e-05194464c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TLE2 SOX18 TCF7L1 NR2F1

4.75e-05194464e141beafc9252e5d8c949252bfab53e127c881dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

4.84e-051954643c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

ERBB4 SHROOM3 NAV2 MEIS1

4.84e-05195464618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

ERBB4 SHROOM3 NAV2 MEIS1

4.84e-0519546406ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB4 SHROOM3 ATP2C2 NAV2

4.84e-051954649406866f99555198a9be311fbd65751b70f35446
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL12A1 NAV2 NR2F1 MEIS1

4.84e-051954643d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

ERBB4 SHROOM3 ATP2C2 NAV2

4.84e-051954641798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

SHROOM3 NACC2 TCF7L1 RBM20

5.04e-051974649d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

SHROOM3 NACC2 TCF7L1 RBM20

5.04e-0519746461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 NAV2 NR2F1 MEIS1

5.04e-051974649b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 SHROOM3 ATP2C2 TCF7L1

5.14e-051984642e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Immature_Interneurons|6_mon / Sample Type, Dataset, Time_group, and Cell type.

AMBN TCF4 ERBB4 TLE2

5.14e-051984645798640425cabf4ac517b7f96a9dfd32f6e5e7c5
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 SHROOM3 ATP2C2 TCF7L1

5.14e-05198464f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

TCF4 COL12A1 NR2F1 MEIS1

5.24e-051994645b9d355795dd03a22f0961dfd143425c367a4654
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

COL12A1 NAV2 NR2F1 MEIS1

5.24e-051994649503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 CELF4 TLE2

5.34e-05200464e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCF4 NAV2 NR2F1 MEIS1

5.34e-05200464cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Interneuron|6m / Sample Type, Dataset, Time_group, and Cell type.

AMBN TCF4 CELF4 PCLO

5.34e-05200464274871d632bbbe03720726a59ab3ec6d5fa0da11
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 SHROOM3 PCLO ATP2C2

5.34e-05200464d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 CELF4 NR2F1

5.34e-05200464c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

TCF4 ERBB4 TLE2 RXRG

5.34e-052004645ef4a3dc18a44292184a59ced916183c0699b01e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TCF4 ERBB4 NR2F1

2.65e-04121463b2d571f571133c281d72584fe925cebbd2317829
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 NACC2 RXRG

3.27e-041304638bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CELF4 COL12A1 NAV2

4.06e-0414046345d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellControl-NK|World / Disease group and Cell class

TCF4 NAV2 MEIS1

4.32e-04143463fe08adc9472dfd4242497d6c614d0490713261da
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

ATP2C2 SOX18 MEIS1

4.77e-04148463db046a02a00829910bf9d7dbda068e730aa78f00
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

ERBB4 NAV2 SOX18

4.87e-04149463d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

CDK8 UBR4 TCF7L1

4.87e-04149463768877bade04ca0321593b8470b5011ad8270431
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 ATP2C2 SOX18

5.16e-04152463acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 ATP2C2 SOX18

5.16e-041524639d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

CDK8 SMG7 UBR4

5.46e-0415546315bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PCLO ATP2C2 RBM20

5.56e-0415646310d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TLE2 NR2F1 MEIS1

5.88e-041594632607b562903228274fbd96168ba826782fab0b53
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TLE2 NR2F1 MEIS1

5.88e-04159463e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB4 NACC2 TLE2

6.10e-04161463b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 COL12A1 MEIS1

6.10e-041614631b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TLE2 RXRG MEIS1

6.21e-041624635f009b231f21861afee9cc0c569082e1135f929c
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF4 UBR4 SSBP3

6.21e-0416246375df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TLE2 RXRG MEIS1

6.21e-04162463b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 NAV2

6.21e-041624635c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ERBB4 CELF4 NR2F1

6.43e-041644634d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 TCF7L1 MEIS1

6.43e-04164463f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SMG7 PTPN23 ARID1A

6.66e-0416646332d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TCF4 CELF4 NR2F1

6.78e-041674636a03d16165e0b003092c39972928981abd4a75aa
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TCF4 ERBB4 RXRG

6.78e-041674639a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

TCF4 SOX18 MEIS1

6.78e-041674635af9127bae05768a5164d5708a4ad37edca99324
ToppCellsevere-CD4+_T_naive|severe / disease stage, cell group and cell class

CELF4 KCNA7 TLE2

6.78e-0416746302a8215fca59c357c1cdaa5738849eacf98c0bcc
ToppCellControl-NK|Control / Disease group and Cell class

TCF4 NAV2 MEIS1

6.90e-04168463683d389c8a1e791bfc773e63148115a21a6566db
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CELF4 COL12A1 PCLO

7.02e-04169463815474855a70498a74e52f6583113c63b7267a0c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM3 CELF4 COL12A1

7.02e-04169463cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 NR2F1 MEIS1

7.02e-04169463a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

SHROOM3 COL12A1 NAV2

7.14e-04170463e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

ERBB4 SHROOM3 KCNA7

7.14e-04170463269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 TLE2 RXRG

7.39e-0417246335e961c88bfe79046533396912cedf00ca81db7b
Drug3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A

SMG7 TLE2 PCLO ANXA11 ATP2C2 NR2F1

2.42e-061934664426_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

NAV2 ZMIZ1 ARID1A EP300 RNF111

3.08e-051804654541_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

FAM168A NACC2 YLPM1 C11orf24 SLC10A3

3.42e-051844651064_DN
DrugChrysene-1,4-quinone [100900-16-1]; Down 200; 15.4uM; HL60; HG-U133A

TCF4 SMG7 FUBP1 SMARCA2 C11orf24

4.30e-051934651773_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

YLPM1 SMARCA2 C11orf24 EP300 MEIS1

4.30e-051934656967_DN
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; HL60; HG-U133A

CDK8 TCF4 ANXA11 C11orf24 ARID1A

4.40e-051944651424_DN
DrugScoulerine [6451-73-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

TCF4 SMG7 FUBP1 PCLO ATP2C2

4.62e-051964655111_DN
DrugStreptozotocin [18883-66-4]; Down 200; 15uM; MCF7; HT_HG-U133A

SMG7 FAM168A TLE2 ARID1A MEIS1

4.85e-051984657193_DN
Drugtroglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA

CDK8 FAM168A NACC2 ATP2C2 ARID1A

4.85e-051984651070_DN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

TLE2 YLPM1 NAV2 NR2F1 MEIS1

4.85e-051984656930_UP
Diseaseobsolete aging, cognition

PRR20C PRR20D PRR20B PRR20E PRR20A

3.04e-1115495EFO_0003925, GO_0007568
Diseaseirritable bowel syndrome

TCF4 ERBB4 CELF4 PCLO YLPM1 EP300

8.16e-08131496EFO_0000555
Diseaset-tau:beta-amyloid 1-42 ratio measurement

PRR20C PRR20D PRR20B PRR20E PRR20A

8.48e-0866495EFO_0007708
Diseasemosaic loss of chromosome Y measurement

PRR20C PRR20D PRR20B PRR20E PRR20A

2.24e-0780495EFO_0007783
DiseaseTinnitus, wellbeing measurement

PRR20C PRR20D PRR20B PRR20E PRR20A

5.59e-0796495EFO_0007869, HP_0000360
Diseasefeeling "fed-up" measurement

TCF4 ERBB4 CELF4 YLPM1

7.88e-0676494EFO_0009588
Diseasetelomere length

PRR20C PRR20D CELF4 PRR20B PRR20E PRR20A

1.29e-05313496EFO_0004505
Diseasealcohol use disorder (implicated_via_orthology)

ERBB4 SMARCA2 SMARCD2 ARID1A EP300

1.80e-05195495DOID:1574 (implicated_via_orthology)
Diseaseelectrocardiography

KCNA7 NAV2 ZMIZ1 SSBP3 RBM20 RXRG MEIS1

2.59e-05530497EFO_0004327
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 ARID1A

2.69e-055492C3281201
Diseaseneuroticism measurement, cognitive function measurement

ERBB4 CELF4 PCLO YLPM1 NAV2 R3HDM2 ARID1A

3.94e-05566497EFO_0007660, EFO_0008354
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB4 ARID1A EP300

4.39e-0541493C0496956
DiseaseBreast adenocarcinoma

ERBB4 ARID1A EP300

4.39e-0541493C0858252
Diseaseoccupational attainment

TCF4 ERBB4 CELF4

4.72e-0542493EFO_0020977
Diseasechildhood gender nonconformity

SMARCA2 NAV2 SSBP3

5.07e-0543493EFO_0020103
Diseaseage at menarche

TCF4 ERBB4 SMARCA2 SSBP3 ARID1A NR2F1 RXRG

5.34e-05594497EFO_0004703
DiseaseMalignant neoplasm of breast

ERBB4 UBR4 MPLKIP ZMIZ1 ARID1A TCF7L1 EP300 NR2F1 MEIS1

6.00e-051074499C0006142
Diseasemood instability measurement

TCF4 CELF4 YLPM1 EP300

6.15e-05128494EFO_0008475
Diseaseapolipoprotein A 1 measurement

FAM168A YLPM1 R3HDM2 ZMIZ1 ARID1A TCF7L1 MEIS1 RNF111

7.15e-05848498EFO_0004614
Diseaseunipolar depression, mood disorder

TCF4 ERBB4 CELF4 YLPM1

7.35e-05134494EFO_0003761, EFO_0004247
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCD2 ARID1A

9.65e-059492DOID:1925 (implicated_via_orthology)
Diseaseglucagon-like peptide-1 measurement

AMBN COL12A1

1.21e-0410492EFO_0008465
Diseasemajor depressive disorder

TCF4 ERBB4 CELF4 PCLO

1.29e-04155494MONDO_0002009
Diseasecoffee consumption measurement, neuroticism measurement

TCF4 CELF4 YLPM1

1.91e-0467493EFO_0006781, EFO_0007660
DiseaseCoffin-Siris syndrome

SMARCA2 ARID1A

2.08e-0413492C0265338
Diseasechronic obstructive pulmonary disease, surfactant protein D measurement

ANXA11 ATP2C2

2.08e-0413492EFO_0000341, EFO_0005081
DiseaseT-Cell Lymphoma

ARID1A EP300

3.19e-0416492C0079772
Diseasenervousness

CELF4 YLPM1

3.19e-0416492NCIT_C74532
Diseaseatrial fibrillation

ERBB4 NAV2 ZMIZ1 RBM20 RXRG

3.70e-04371495EFO_0000275
DiseaseFeeding difficulties

CDK8 ZMIZ1

4.06e-0418492C0232466
DiseaseAdenocarcinoma of large intestine

CDK8 ERBB4 EP300

5.52e-0496493C1319315
DiseaseAdenoid Cystic Carcinoma

SMARCA2 ARID1A EP300

6.21e-04100493C0010606
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

TCF4 SMARCA2 ZMIZ1

6.40e-04101493EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseaseneurotic disorder

CELF4 PCLO YLPM1

6.40e-04101493EFO_0004257
Diseasegastroesophageal reflux disease

ERBB4 CELF4 YLPM1

6.40e-04101493EFO_0003948
Diseasedepressive symptom measurement

TCF4 ERBB4 CELF4 PCLO YLPM1

6.93e-04426495EFO_0007006
Diseaseglycerol measurement

PCLO SMARCA2

8.56e-0426492EFO_0010115
Diseasevital capacity

SHROOM3 PCLO SMARCA2 SMARCD2 VTA1 ZMIZ1 SSBP4 RBM20

9.05e-041236498EFO_0004312
Diseaseunipolar depression, irritable bowel syndrome

TCF4 PCLO

9.93e-0428492EFO_0000555, EFO_0003761
Diseaseself rated health

TCF4 SEC24C

1.22e-0331492EFO_0004778
Diseaseparental longevity

ERBB4 SHROOM3 PCLO YLPM1 SMARCA2

1.34e-03494495EFO_0007796
Diseasemonocyte count

TCF4 YLPM1 R3HDM2 ZMIZ1 SSBP4 SSBP3 TCF7L1 MEIS1

1.38e-031320498EFO_0005091
Diseasehousehold income

TCF4 ERBB4 CELF4 SMARCA2

1.63e-03304494EFO_0009695

Protein segments in the cluster

PeptideGeneStartEntry
RGQVPGYPPSQNPGM

BAG4

201

O95429
SPPPAYTPMSGNQFV

ERBB4

1051

Q15303
NPPMGYGPRMQQPSN

EP300

746

Q09472
NSMPPYLPRTQAAGP

EP300

1881

Q09472
GQPPSAQQPVPPYGM

ANXA11

91

P50995
RPPPGTQGMLEQYLN

B3GALT5-AS1

36

P59052
HGPMPQNKQSPLYPG

AMBN

226

Q9NP70
TMYNNGGIPLPLTPQ

ATP2C2

521

O75185
PPGSEQYQMPQSPSP

R3HDM2

671

Q9Y2K5
FSPPSQTRGPGPSMN

RBM20

171

Q5T481
MPPTQPNPGQYALTN

NR2F1

161

P10589
YGPAPSTRPMGPQAA

PTPN23

1051

Q9H3S7
AVSQGTPYNPDGQPM

MEIS1

341

O00470
GNQMPPRPPSGQSDS

ARID1A

721

O14497
NPQMPQYSSPQPGSA

ARID1A

756

O14497
MQRQNFRPPTPPYPG

MPLKIP

1

Q8TAP9
SPVQPGAPYGNPKNM

FAM168A

6

Q92567
YAQTSPQGMPQHPPA

FUBP1

626

Q96AE4
QDPYRGMPPGLQGQS

TCF4

491

P15884
MSQAPGAQPSPPTVY

JOSD2

1

Q8TAC2
PQYSTARMTPPPGPQ

PCLO

3061

Q9Y6V0
QYPGQANRTAPGPML

SLC10A3

91

P09131
RSMAPNQASGGPPPE

PRR20D

11

P86480
RSMAPNQASGGPPPE

PRR20A

11

P86496
RSMAPNQASGGPPPE

PRR20B

11

P86481
NGSSQMPGNPPRLPF

KCNA7

191

Q96RP8
PNDYQSSRNQPGPPG

COL12A1

2931

Q99715
YPNPGPSTSQPQSSM

CDK8

431

P49336
GPVPGYQQTPPQGMS

SEC24C

46

P53992
YQQTPPQGMSRAPPS

SEC24C

51

P53992
PQNYGSGMRPPPNSL

SSBP3

216

Q9BWW4
PQAMSQPNRGPSPFS

SMARCA2

161

P51531
RSMAPNQASGGPPPE

PRR20C

11

P86479
IPYSQQRPSGPGPMN

SMG7

716

Q92540
PSMGNGYPPRANASR

NAV2

821

Q8IVL1
RSMAPNQASGGPPPE

PRR20E

11

P86478
GQTGRQPLPPYTPAM

SHROOM3

1371

Q8TF72
GPAAQYQRPGMSPGN

SMARCD2

66

Q92925
YGQISQAFPQPPPMI

CELF4

396

Q9BZC1
PSPMPYTQRAAGPGT

C11orf24

326

Q96F05
YGSSMVAQPQPQPPP

RNF111

621

Q6ZNA4
LVPQQGQPMYSLPPG

TCF7L1

251

Q9HCS4
QPGMAPSQPGAYQPR

TFG

346

Q92734
MTPPPSGPNPYARNR

TFG

371

Q92734
PSNMPSGNYTGIQIP

VTA1

201

Q9NP79
PQSYGGGMRPPPNSL

SSBP4

211

Q9BWG4
PGLPGIGNMNYPSTS

RXRG

116

P48443
LQNTSSRPGMYPPPG

YLPM1

1496

P49750
MQRSPPGYGAQDDPP

SOX18

1

P35713
RMPGNPYSSNEPGIG

UBR4

4366

Q5T4S7
MYPQGRHPTPLQSGQ

TLE2

1

Q04725
HGQRMPQQTYPGPRP

ZMIZ1

381

Q9ULJ6
TSPNYPGQRMPSQPS

ZMIZ1

441

Q9ULJ6
PGQRMPSQPSSGQYP

ZMIZ1

446

Q9ULJ6
IQQMPYPQGERTSPG

NACC2

236

Q96BF6