Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enzyme regulator activity	RIN3 TAGAP LRRK2 GBP2 GBP3 BCR HMSD SERPINB5 PIK3CA SERPINB3 STRADA SERPINB4 SGSM2 RAB3GAP2 CLPS PPME1 HERC1 BSN GMPPA FGD2 KALRN TOM1L1 APC BIRC2 SHOC2 DENND4C WDR91 USP14 PPP2R3A EGFR LRP6 TEN1 PRDM14 MTMR9	8.38e-07	1418	194	34	GO:0030234
GeneOntologyMolecularFunction	actin binding	XIRP1 MAP2 MYO7A TRPC5 LRRK2 GBP2 GBP3 ACE SYNE2 DIAPH3 UTRN PLS1 HIP1R EGFR MYO16	7.25e-05	479	194	15	GO:0003779
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	9.39e-05	2	194	2	GO:0003989
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	DCAF1 SPEG LRRK2 BCR NUAK1 PIK3CA FASTK STRADA KALRN MAP3K6 EGFR PRKDC MAPK3 MAP2K5	1.23e-04	446	194	14	GO:0004674
GeneOntologyMolecularFunction	GDP phosphatase activity	GBP2 GBP3 ENTPD4	1.86e-04	12	194	3	GO:0004382
GeneOntologyMolecularFunction	protein serine kinase activity	DCAF1 SPEG LRRK2 BCR NUAK1 PIK3CA FASTK KALRN MAP3K6 PRKDC MAPK3 MAP2K5	2.36e-04	363	194	12	GO:0106310
GeneOntologyMolecularFunction	peptidyl-dipeptidase activity	ACE ACE2	2.80e-04	3	194	2	GO:0008241
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	DCAF1 HK3 SPEG INSRR LRRK2 FPGT BCR NUAK1 PIK3CA FASTK STRADA CLP1 KALRN POLA1 TUT7 TEP1 MAP3K6 EGFR PRKDC MAPK3 MAP2K5	3.27e-04	938	194	21	GO:0016772
GeneOntologyMolecularFunction	enzyme inhibitor activity	LRRK2 GBP2 GBP3 HMSD SERPINB5 SERPINB3 SERPINB4 PPME1 BSN GMPPA USP14 LRP6 TEN1	3.46e-04	435	194	13	GO:0004857
GeneOntologyMolecularFunction	insulin receptor substrate binding	INSRR PIK3CA ZNF592	3.77e-04	15	194	3	GO:0043560
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	DCAF1 HK3 SPEG INSRR LRRK2 BCR NUAK1 PIK3CA FASTK STRADA CLP1 KALRN MAP3K6 EGFR PRKDC MAPK3 MAP2K5	5.77e-04	709	194	17	GO:0016773
GeneOntologyMolecularFunction	protein kinase activity	DCAF1 SPEG INSRR LRRK2 BCR NUAK1 PIK3CA FASTK STRADA KALRN MAP3K6 EGFR PRKDC MAPK3 MAP2K5	8.00e-04	600	194	15	GO:0004672
GeneOntologyMolecularFunction	nucleoside diphosphate phosphatase activity	GBP2 GBP3 ENTPD4	9.11e-04	20	194	3	GO:0017110
GeneOntologyMolecularFunction	clathrin adaptor activity	AP2A2 AP1G2 HIP1R	1.21e-03	22	194	3	GO:0035615
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	DCAF1 PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.22e-03	82	194	5	GO:1990756
GeneOntologyMolecularFunction	kinase activity	DCAF1 HK3 SPEG INSRR LRRK2 BCR NUAK1 PIK3CA FASTK STRADA CLP1 KALRN MAP3K6 EGFR PRKDC MAPK3 MAP2K5	1.31e-03	764	194	17	GO:0016301
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA ACACB	1.37e-03	6	194	2	GO:0016421
GeneOntologyMolecularFunction	piRNA binding	MOV10L1 PIWIL3	1.37e-03	6	194	2	GO:0034584
GeneOntologyMolecularFunction	biotin binding	ACACA ACACB	1.37e-03	6	194	2	GO:0009374
GeneOntologyMolecularFunction	cargo adaptor activity	AP2A2 AP1G2 HIP1R	1.77e-03	25	194	3	GO:0140312
GeneOntologyMolecularFunction	ligase activity, forming carbon-carbon bonds	ACACA ACACB	1.91e-03	7	194	2	GO:0016885
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	GBP2 GBP3 HMSD SERPINB5 SERPINB3 SERPINB4 USP14	1.93e-03	180	194	7	GO:0004866
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RIN3 TAGAP BCR RAB3GAP2 HERC1 FGD2 KALRN DENND4C	1.94e-03	231	194	8	GO:0005085
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.00e-03	55	194	4	GO:0042974
GeneOntologyMolecularFunction	molecular function inhibitor activity	LRRK2 GBP2 GBP3 HMSD SERPINB5 SERPINB3 SERPINB4 PPME1 BSN GMPPA NLRC3 USP14 LRP6 TEN1	2.13e-03	596	194	14	GO:0140678
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	LRRK2 MAP3K6 EGFR	2.22e-03	27	194	3	GO:0004709
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	DCAF1 PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.35e-03	95	194	5	GO:0140767
GeneOntologyMolecularFunction	peptidase inhibitor activity	GBP2 GBP3 HMSD SERPINB5 SERPINB3 SERPINB4 USP14	2.39e-03	187	194	7	GO:0030414
GeneOntologyMolecularFunction	cytoskeletal protein binding	XIRP1 MAP2 MYO7A TRPC5 LRRK2 GBP2 GBP3 ACE S100A6 SYNE2 DIAPH3 UTRN PLS1 RAD51D TOGARAM2 HIP1R APC EGFR IRAG2 MYO16 KIF1C	2.40e-03	1099	194	21	GO:0008092
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	BSN RIMBP2	2.53e-03	8	194	2	GO:0098882
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF7 PRAMEF5 ZSWIM4 PRAMEF6 PRAMEF8	7.67e-05	47	196	5	GO:0031462
GeneOntologyCellularComponent	vesicle membrane	GAD2 AQP11 COPE LRRK2 GBP2 GBP3 AP2A2 AP1G2 C4BPA C5AR1 DIAPH3 BSN DSE DOP1B MGAM FGD2 TOM1L1 HIP1R APC PLA2G4E DENND4C WDR91 ACE2 EGFR AP5M1 IRAG2 LRP6	1.17e-04	1325	196	27	GO:0012506
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	GAD2 AQP11 COPE LRRK2 GBP2 AP2A2 AP1G2 C4BPA C5AR1 DIAPH3 BSN DSE DOP1B MGAM FGD2 TOM1L1 HIP1R APC PLA2G4E DENND4C WDR91 ACE2 EGFR AP5M1 IRAG2 LRP6	2.32e-04	1307	196	26	GO:0030659
GeneOntologyCellularComponent	stereocilia tip link	MYO7A DIAPH3	2.61e-04	3	196	2	GO:0002140
GeneOntologyCellularComponent	stereocilia tip-link density	MYO7A DIAPH3	2.61e-04	3	196	2	GO:1990427
GeneOntologyCellularComponent	Wnt signalosome	LRRK2 APC LRP6	4.15e-04	16	196	3	GO:1990909
GeneOntologyCellularComponent	AP-5 adaptor complex	AP5Z1 AP5M1	5.18e-04	4	196	2	GO:0044599
GeneOntologyCellularComponent	ruffle membrane	MAP2 FGD2 HIP1R APC EGFR MTMR9	5.45e-04	108	196	6	GO:0032587
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	DCAF1 PRAMEF7 PRAMEF5 FBXL12 ZSWIM4 PRAMEF6 DMAC2 PRAMEF8	9.01e-04	212	196	8	GO:0031461
GeneOntologyCellularComponent	AP-type membrane coat adaptor complex	AP2A2 AP5Z1 AP1G2 AP5M1	1.06e-03	48	196	4	GO:0030119
GeneOntologyCellularComponent	multivesicular body, internal vesicle	LRRK2 EGFR	1.28e-03	6	196	2	GO:0097487
GeneOntologyCellularComponent	host intracellular region	GBP2 GBP3	1.28e-03	6	196	2	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP2 GBP3	1.28e-03	6	196	2	GO:0030430
GeneOntologyCellularComponent	host cell part	GBP2 GBP3	1.28e-03	6	196	2	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP2 GBP3	1.28e-03	6	196	2	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP2 GBP3	1.28e-03	6	196	2	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP2 GBP3	1.28e-03	6	196	2	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP2 GBP3	1.28e-03	6	196	2	GO:0020005
GeneOntologyCellularComponent	ubiquitin ligase complex	DCAF1 PRAMEF7 PRAMEF5 FBXL12 ZSWIM4 MED7 PRAMEF6 DMAC2 RANBP9 PRAMEF8	1.86e-03	352	196	10	GO:0000151
GeneOntologyCellularComponent	symbiont cell surface	GBP2 GBP3	2.36e-03	8	196	2	GO:0106139
GeneOntologyCellularComponent	stereocilia coupling link	MYO7A DIAPH3	2.36e-03	8	196	2	GO:0002139
GeneOntologyCellularComponent	germ plasm	MOV10L1 TDRD1 PIWIL3	2.48e-03	29	196	3	GO:0060293
GeneOntologyCellularComponent	pole plasm	MOV10L1 TDRD1 PIWIL3	2.48e-03	29	196	3	GO:0045495
GeneOntologyCellularComponent	P granule	MOV10L1 TDRD1 PIWIL3	2.48e-03	29	196	3	GO:0043186
GeneOntologyCellularComponent	cell projection membrane	MAP2 ACE SYNE2 UTRN FGD2 HIP1R APC ACE2 EGFR SLCO1A2 MTMR9	2.59e-03	431	196	11	GO:0031253
Domain	L_dom-like	NLRP11 PRAMEF7 PRAMEF5 INSRR LRRK2 FBXL12 PIDD1 LRRC56 NLRC3 PRAMEF6 LRRC57 DMAC2 PRAMEF8 SHOC2 EGFR LRRC28	3.45e-07	328	194	16	IPR032675
Domain	ARM-type_fold	DCAF1 NBEAL1 LRRK2 USP9Y CLHC1 AP2A2 PIK3CA AP1G2 DIAPH3 TOGARAM2 APC MROH8 PRKDC TNPO3 STAG2	2.73e-06	339	194	15	IPR016024
Domain	-	NLRP11 PRAMEF7 PRAMEF5 LRRK2 FBXL12 PIDD1 LRRC56 NLRC3 PRAMEF6 LRRC57 DMAC2 PRAMEF8 SHOC2 LRRC28	6.98e-06	321	194	14	3.80.10.10
Domain	PRAME_family	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	3.87e-05	19	194	4	IPR026271
Domain	Quino_amine_DH_bsu	LRRK2 TENM2 TEP1 NBAS	7.13e-05	22	194	4	IPR011044
Domain	ACC_central	ACACA ACACB	1.07e-04	2	194	2	PF08326
Domain	AcCoA_COase_cen	ACACA ACACB	1.07e-04	2	194	2	IPR013537
Domain	Peptidase_M2	ACE ACE2	1.07e-04	2	194	2	PF01401
Domain	ARM-like	DCAF1 LRRK2 USP9Y AP2A2 AP5Z1 AP1G2 TOGARAM2 APC PRKDC TNPO3 STAG2	1.26e-04	270	194	11	IPR011989
Domain	Peptidase_M2	ACE ACE2	3.20e-04	3	194	2	IPR001548
Domain	SPEC	SYNE2 UTRN SESTD1 KALRN	3.23e-04	32	194	4	SM00150
Domain	Spectrin/alpha-actinin	SYNE2 UTRN SESTD1 KALRN	3.23e-04	32	194	4	IPR018159
Domain	Serpin_dom	HMSD SERPINB5 SERPINB3 SERPINB4	5.13e-04	36	194	4	IPR023796
Domain	-	DCAF1 LRRK2 AP2A2 AP5Z1 AP1G2 TOGARAM2 APC PRKDC TNPO3	5.36e-04	222	194	9	1.25.10.10
Domain	SERPIN	HMSD SERPINB5 SERPINB3 SERPINB4	5.70e-04	37	194	4	PS00284
Domain	Serpin	HMSD SERPINB5 SERPINB3 SERPINB4	6.32e-04	38	194	4	PF00079
Domain	Carboxyl_trans	ACACA ACACB	6.35e-04	4	194	2	PF01039
Domain	COA_CT_CTER	ACACA ACACB	6.35e-04	4	194	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	6.35e-04	4	194	2	PS50980
Domain	COA_CT_N	ACACA ACACB	6.35e-04	4	194	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	6.35e-04	4	194	2	IPR011763
Domain	Carboxyl_trans	ACACA ACACB	6.35e-04	4	194	2	IPR000022
Domain	Serpin_fam	HMSD SERPINB5 SERPINB3 SERPINB4	6.98e-04	39	194	4	IPR000215
Domain	Biotin_BS	ACACA ACACB	1.05e-03	5	194	2	IPR001882
Domain	Biotin_COase_C	ACACA ACACB	1.05e-03	5	194	2	IPR005482
Domain	BC	ACACA ACACB	1.05e-03	5	194	2	PS50979
Domain	Biotin_carb_C	ACACA ACACB	1.05e-03	5	194	2	SM00878
Domain	Biotin_carb_C	ACACA ACACB	1.05e-03	5	194	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB	1.05e-03	5	194	2	IPR011764
Domain	CPSASE_1	ACACA ACACB	1.05e-03	5	194	2	PS00866
Domain	BIOTIN	ACACA ACACB	1.05e-03	5	194	2	PS00188
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RIN3 ACACA MYO7A SPEG FBXL12 CARD10 NCLN BCR RYR1 PLEKHH3 HIRA NUAK1 SGSM2 LRRC56 AP1G2 HERC1 LPAR5 KALRN HIP1R TEP1 SLC2A1 RADIL ZNF592 PRKDC TNPO3	4.52e-09	1105	197	25	35748872
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ACACA MYO7A PIDD1 RYR1 UTRN PLS1 DSE DOP1B FAT4 LPAR5 NACC1 POLA1 IARS1 NELFB IGDCC3 MROH8 ZNF592 PRKDC POTEA MTMR9	8.92e-09	736	197	20	29676528
Pubmed	A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.	SERPINB5 SERPINB3 SERPINB4	1.79e-07	3	197	3	7724531
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACA ACACB MDH1 BCR RAB3GAP2 DIAPH3 CLP1 UTRN NACC1 APC TTC27 DENND4C ZNF592	8.89e-07	418	197	13	34709266
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF7 PRAMEF5 MOV10L1 PRAMEF6 PRAMEF8 TDRD1	1.07e-06	59	197	6	11279525
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACA ACACB MAP2 MYO7A SPEG KCMF1 NCLN USP9Y BLM HERC1 HSPA4L TOGARAM2 VPS13D ZNF592	1.08e-06	497	197	14	36774506
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	ACACA COPE FBXL12 NCLN BCR UMPS GMPPA PMPCB HSPA4L DMAC2 HIP1R TTC27 MAP3K6 SLC2A1 VPS13D	2.19e-06	606	197	15	36538041
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.24e-06	17	197	4	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.24e-06	17	197	4	37781892
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.87e-06	18	197	4	39181896
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.87e-06	18	197	4	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.87e-06	18	197	4	14675769
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.87e-06	18	197	4	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.87e-06	18	197	4	12890732
Pubmed	Molecular characteristics in papillary thyroid cancers (PTCs) with no 131I uptake.	TPO SLC2A1 TG	3.54e-06	6	197	3	17854396
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	3.62e-06	19	197	4	28604677
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ACACA COPE GBP3 MDH1 ACE RYR1 S100A6 AP2A2 MOV10L1 UTRN IARS1 EPG5 USP14 NBAS PRKDC DDX39A MYO16	3.99e-06	807	197	17	30575818
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	4.51e-06	20	197	4	26694250
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	4.51e-06	20	197	4	21425410
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	4.51e-06	20	197	4	16580637
Pubmed	AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.	ACACA ACACB MAP2 APC	5.54e-06	21	197	4	19217427
Pubmed	The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.	GBP2 GBP3 PIK3CA	6.16e-06	7	197	3	20505078
Pubmed	DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.	APC LRP6 PRKDC	6.16e-06	7	197	3	29431745
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	ACACA COPE KCMF1 AP2A2 RAB3GAP2 DIAPH3 HIP1R MAPK3 TNPO3 STAG2	6.40e-06	288	197	10	23383273
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	6.74e-06	22	197	4	31729367
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	8.13e-06	23	197	4	19480014
Pubmed	The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.	ACACA ACACB MAPK3	9.82e-06	8	197	3	36001969
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	AP2A2 AP1G2 DOP1B IARS1 TTC27 EGFR PRKDC TNPO3	1.05e-05	183	197	8	23956138
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.15e-05	25	197	4	12620990
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.15e-05	25	197	4	37451217
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DCAF1 CNNM2 FBXL12 SIX4 NCLN BCR UMPS DIAPH3 UTRN PLS1 PMPCB HSPA4L RANBP9 TTC27 PRKDC MAPK3 GFM1 TNPO3	1.23e-05	974	197	18	28675297
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.35e-05	26	197	4	18500982
Pubmed	Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.	PIK3CA SLC2A1 EGFR MAPK3	1.58e-05	27	197	4	28542142
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.84e-05	28	197	4	25089626
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8 MAPK3	1.99e-05	58	197	5	31598710
Pubmed	Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures.	TPO TG MAPK3	2.09e-05	10	197	3	37964961
Pubmed	The regulation and deregulation of Wnt signaling by PARK genes in health and disease.	LRRK2 APC LRP6	2.09e-05	10	197	3	24115276
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	DCAF1 ACACA USP9Y BCR AP2A2 PIK3CA RAB3GAP2 IARS1 PRKDC	2.29e-05	266	197	9	19380743
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ACACA KCMF1 CCDC178 NUAK1 PIK3CA SERPINB3 STRADA SERPINB4 RAB3GAP2 PPME1 DIAPH3 LCMT1 RAD51D PMPCB NACC1 POLA1 TMEM121 TRMU USP14 NBAS MTMR9	2.32e-05	1327	197	21	32694731
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	2.44e-05	30	197	4	38786026
Pubmed	Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.	SERPINB5 SERPINB3 SERPINB4	2.86e-05	11	197	3	15203215
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ACACA MAP2 COPE KCMF1 GBP2 RAB3GAP2 PPME1 HERC1 GMPPA PLS1 HSPA4L POLA1 IARS1 TOM1L1 RANBP9 NELFB THUMPD1 USP14 N4BP1 PRKDC DDX39A TNPO3	2.93e-05	1455	197	22	22863883
Pubmed	Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.	PIK3CA EGFR LRP6 MAPK3	3.17e-05	32	197	4	34193412
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	3.17e-05	32	197	4	37889087
Pubmed	Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure.	SERPINB3 SERPINB4	3.19e-05	2	197	2	23354406
Pubmed	Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme.	ACE ACE2	3.19e-05	2	197	2	12459472
Pubmed	Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse.	ACE ACE2	3.19e-05	2	197	2	28273875
Pubmed	Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections.	ACE ACE2	3.19e-05	2	197	2	24800825
Pubmed	Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.	ACE ACE2	3.19e-05	2	197	2	18356559
Pubmed	Role of the regulatory domain of the EGF-receptor cytoplasmic tail in selective binding of the clathrin-associated complex AP-2.	AP2A2 EGFR	3.19e-05	2	197	2	8548289
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	3.19e-05	2	197	2	24944901
Pubmed	Angiotensin-converting enzyme 2 is an essential regulator of heart function.	ACE ACE2	3.19e-05	2	197	2	12075344
Pubmed	Elevated Thyroid Autoantibodies Aggravate Stroke Severity in Euthyroidism with Acute Ischemic Stroke.	TPO TG	3.19e-05	2	197	2	35256895
Pubmed	S100A6 activates EGFR and its downstream signaling in HaCaT keratinocytes.	S100A6 EGFR	3.19e-05	2	197	2	30805941
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	3.19e-05	2	197	2	20139635
Pubmed	SCCA2-like serpins mediate genetic predisposition to skin tumors.	SERPINB3 SERPINB4	3.19e-05	2	197	2	12702576
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	3.19e-05	2	197	2	26976583
Pubmed	Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis.	APC LRP6	3.19e-05	2	197	2	34359960
Pubmed	DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation.	DIAPH3 EGFR	3.19e-05	2	197	2	35538918
Pubmed	Angiotensin converting enzymes ACE and ACE2 in thyroid cancer progression.	ACE ACE2	3.19e-05	2	197	2	31847529
Pubmed	Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.	SERPINB3 SERPINB4	3.19e-05	2	197	2	35022507
Pubmed	EGFR Signaling Regulates Maspin/SerpinB5 Phosphorylation and Nuclear Localization in Mammary Epithelial Cells.	SERPINB5 EGFR	3.19e-05	2	197	2	27447178
Pubmed	Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability.	TPO TG	3.19e-05	2	197	2	27305979
Pubmed	Squamous cell carcinoma antigen production in nasal inverted papilloma.	SERPINB3 SERPINB4	3.19e-05	2	197	2	23168150
Pubmed	Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients.	ACE ACE2	3.19e-05	2	197	2	19684612
Pubmed	PIK3CA mutations and specific treatment: do not forget lessons from RAS mutations and EGFR targeting.	PIK3CA EGFR	3.19e-05	2	197	2	31970497
Pubmed	Role of angiotensin-converting enzyme (ACE and ACE2) imbalance on tourniquet-induced remote kidney injury in a mouse hindlimb ischemia-reperfusion model.	ACE ACE2	3.19e-05	2	197	2	22580272
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	3.19e-05	2	197	2	10677481
Pubmed	Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice.	PPME1 LCMT1	3.19e-05	2	197	2	32341098
Pubmed	Gene polymorphisms in angiotensin I converting enzyme (ACE I/D) and angiotensin II converting enzyme (ACE2 C-->T) protect against cerebral malaria in Indian adults.	ACE ACE2	3.19e-05	2	197	2	20117248
Pubmed	Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.	SERPINB3 SERPINB4	3.19e-05	2	197	2	10653592
Pubmed	Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.	SERPINB3 SERPINB4	3.19e-05	2	197	2	29112685
Pubmed	Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.	SERPINB3 SERPINB4	3.19e-05	2	197	2	10956412
Pubmed	SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.	SERPINB3 SERPINB4	3.19e-05	2	197	2	35874657
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	3.19e-05	2	197	2	25282359
Pubmed	Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.	SERPINB3 SERPINB4	3.19e-05	2	197	2	27668655
Pubmed	High EGFR protein expression and exon 9 PIK3CA mutations are independent prognostic factors in triple negative breast cancers.	PIK3CA EGFR	3.19e-05	2	197	2	26680641
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	3.19e-05	2	197	2	27693630
Pubmed	Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.	APC PRKDC	3.19e-05	2	197	2	8567125
Pubmed	ACE2 gene expression is up-regulated in the human failing heart.	ACE ACE2	3.19e-05	2	197	2	15151696
Pubmed	APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells.	PIK3CA APC	3.19e-05	2	197	2	37968472
Pubmed	Angiotensin converting enzyme insertion/deletion genetic polymorphism: its impact on renal function in critically ill patients.	ACE ACE2	3.19e-05	2	197	2	19020433
Pubmed	The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases.	ACE ACE2	3.19e-05	2	197	2	17504232
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	3.19e-05	2	197	2	32215608
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	3.19e-05	2	197	2	29772612
Pubmed	EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators.	APC EGFR	3.19e-05	2	197	2	21653642
Pubmed	Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio.	ACE ACE2	3.19e-05	2	197	2	17303661
Pubmed	Assessment of angiotensin converting enzyme gene polymorphism in preeclampsia mothers of Bangladesh.	ACE ACE2	3.19e-05	2	197	2	33241696
Pubmed	Genotype variation of ACE and ACE2 genes affects the severity of COVID-19 patients.	ACE ACE2	3.19e-05	2	197	2	37667339
Pubmed	A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size.	PPME1 LCMT1	3.19e-05	2	197	2	25839665
Pubmed	Lack of a role for cross-reacting anti-thyroid antibodies in chronic idiopathic urticaria.	TPO TG	3.19e-05	2	197	2	20182447
Pubmed	EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment.	EGFR PRKDC	3.19e-05	2	197	2	21266349
Pubmed	[Expression and significance of GLUT-1 and DNA-PKcs in serous ovarian tumors].	SLC2A1 PRKDC	3.19e-05	2	197	2	17991316
Pubmed	Association investigations between ACE1 and ACE2 polymorphisms and severity of COVID-19 disease.	ACE ACE2	3.19e-05	2	197	2	36255490
Pubmed	Enhanced tumor formation in mice heterozygous for Blm mutation.	BLM APC	3.19e-05	2	197	2	12242442
Pubmed	Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy.	ACE ACE2	3.19e-05	2	197	2	18389211
Pubmed	Polymorphisms in the human angiotensin converting enzyme gene (ACE) linked to susceptibility of COVID-19 and malaria infections in the Ghanaian population.	ACE ACE2	3.19e-05	2	197	2	38367677
Pubmed	Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.	SERPINB3 SERPINB4	3.19e-05	2	197	2	21403642
Pubmed	Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter.	SERPINB3 SERPINB4	3.19e-05	2	197	2	11267667
Pubmed	Impact of Concurrent PIK3CA Mutations on Response to EGFR Tyrosine Kinase Inhibition in EGFR-Mutant Lung Cancers and on Prognosis in Oncogene-Driven Lung Adenocarcinomas.	PIK3CA EGFR	3.19e-05	2	197	2	26334752
Cytoband	1p36.21	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.61e-04	63	197	4	1p36.21
GeneFamily	PRAME family	PRAMEF7 PRAMEF5 PRAMEF6 PRAMEF8	1.66e-05	24	118	4	686
GeneFamily	Protein phosphatase 2 modulatory subunits	PPME1 LCMT1	4.17e-04	5	118	2	1265
GeneFamily	Cohesin complex	STAG2 SMC1B	1.15e-03	8	118	2	1060
GeneFamily	WD repeat domain containing	WDR64 NBEAL1 HIRA HERC1 WDR49 TEP1 WDR91	1.67e-03	262	118	7	362
GeneFamily	Serpin peptidase inhibitors	SERPINB5 SERPINB3 SERPINB4	1.79e-03	37	118	3	739
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	GAD2 MAP2 SPEG FBXL12 TENM2 NUAK1 NALCN HERC1 BSN USP49 GPR26 KALRN APC PPP2R3A TRIM13	2.32e-06	465	195	15	M39066
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED	PRAMEF7 PRAMEF5 SPEG PRAMEF6 PRAMEF8 TDRD1	4.16e-06	57	195	6	MM1262
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	RYR1 SERPINB5 SERPINB4 DSE LPAR5 HSPA4L SLC2A1 PPP2R3A EGFR N4BP1	1.31e-08	189	197	10	533c302df467d13ab639232daf4f8cafb808260b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 CEP85L GBP2 GBP3 SYNE2 UTRN TUT7 N4BP1 STAG2	1.05e-07	178	197	9	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	facs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CLHC1 RYR1 PLEKHH3 HOXD3 CREG2 GMPPA PLS1 NBAS	1.33e-07	183	197	9	b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCell	Tuft-tuft-1\|World / Class top	MYO7A AQP11 NUAK1 SESTD1 FAAP24 NBAS IRAG2 ALOXE3	8.56e-07	168	197	8	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP2 CCDC178 TENM2 SERPINB5 SERPINB3 SERPINB4 DSE IRAG2	1.02e-06	172	197	8	aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP2 CCDC178 TENM2 SERPINB5 SERPINB3 SERPINB4 DSE IRAG2	1.02e-06	172	197	8	bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NUAK1 SERPINB3 SERPINB4 C5AR1 WDR49 SLC2A1 EGFR IRAG2	2.93e-06	198	197	8	5374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 BSN CLP1 MACC1 LPAR5 FGD2 IRAG2	8.63e-06	164	197	7	54f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCell	facs-Marrow-T-cells-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CLHC1 PLEKHH3 HOXD3 CREG2 GMPPA PLS1	1.64e-05	181	197	7	57f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCell	facs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CLHC1 PLEKHH3 HOXD3 CREG2 GMPPA PLS1	1.64e-05	181	197	7	d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 DIAPH3 UTRN MACC1 EGFR SLCO1A2	2.09e-05	188	197	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 SYNE2 DIAPH3 PPP2R3A EGFR SLCO1A2	2.31e-05	191	197	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 TTC39C SNRNP25 SHOC2 TDRD1 MAP3K6 ACE2	2.47e-05	193	197	7	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	TPO MAP2 SYNE2 CFAP161 UTRN KALRN MAP3K6	2.56e-05	194	197	7	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	TPO MAP2 CARD10 SYNE2 UTRN KALRN MAP3K6	2.64e-05	195	197	7	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TENM2 SERPINB5 NUAK1 SERPINB3 SERPINB4 SYNE2 EGFR	2.73e-05	196	197	7	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL\|Int-URO / Disease, condition lineage and cell class	SYNE2 MED7 PLS1 LPAR5 PYROXD2 HIP1R DENND4C	2.91e-05	198	197	7	717735d755745439f97ba1b71785c73945dfa9c5
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RYR1 PLEKHH3 S100A6 SERPINB5 SERPINB3 SERPINB4 EGFR	3.01e-05	199	197	7	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	XIRP1 RYR1 MOV10L1 LPAR5 TUT7 WDR91 IRAG2	3.01e-05	199	197	7	e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHH3 SERPINB5 SERPINB3 SERPINB4 HSPA4L SLC2A1 EGFR	3.01e-05	199	197	7	c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLHC1 GPR26 TOGARAM2 IGDCC3 PLA2G4E ACE2	3.92e-05	141	197	6	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLHC1 GPR26 TOGARAM2 IGDCC3 PLA2G4E ACE2	3.92e-05	141	197	6	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLHC1 GPR26 TOGARAM2 IGDCC3 PLA2G4E ACE2	4.08e-05	142	197	6	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG CCDC178 SGSM2 HSPA4L TDRD1 RADIL	7.13e-05	157	197	6	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CCDC178 TENM2 CLHC1 SERPINB5 SERPINB3 SERPINB4	7.91e-05	160	197	6	18ae6822915d16699beb9047baeef9b006901a35
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CCDC178 TENM2 CLHC1 SERPINB5 SERPINB3 SERPINB4	7.91e-05	160	197	6	830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTC39C NLRC3 LPAR5 FGD2 TDRD1 MTMR9	7.91e-05	160	197	6	dee756a2dc9725520d439e7273c489c2284015d8
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HK3 NUAK1 SGSM2 DCLRE1A FAAP24 ZNF592	8.47e-05	162	197	6	ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 SYNE2 DIAPH3 WDR91 PPP2R3A RIMBP2	9.06e-05	164	197	6	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	Leuk-UTI-Lymphocyte-T_NK-CD4_TEM\|Leuk-UTI / Disease, Lineage and Cell Type	IL12RB2 TAGAP NBEAL1 FKBP11 SYNE2 NLRC3	9.37e-05	165	197	6	08285c09de16ed4f488abb655a22f54bc07968ae
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BLM DCLRE1A LCMT1 PMPCB MAP3K6 IQCC	9.37e-05	165	197	6	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	Bac-SEP-Myeloid-tDC\|Bac-SEP / Disease, Lineage and Cell Type	ETFBKMT HMSD TDRD1 TMEM121 MROH8 MSLN	9.37e-05	165	197	6	8728f927502e56f2768b4224e9111939d3d7815a
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACACB TENM2 KCNJ13 DIAPH3 MGAM REG3A	1.03e-04	168	197	6	4e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACACB TENM2 KCNJ13 DIAPH3 MGAM REG3A	1.03e-04	168	197	6	ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	IL12RB2 CEP85L TTC39C GBP2 SYNE2 NLRC3	1.07e-04	169	197	6	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WDR64 INSRR GBP2 SLC22A6 KCNJ13	1.13e-04	107	197	5	4a18261492371d19b8dbd403e197fdf64ef69392
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 KALRN TG WDR91 ACE2 HECTD2	1.14e-04	171	197	6	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 KALRN TG WDR91 ACE2 HECTD2	1.14e-04	171	197	6	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	IL12RB2 TENM2 SERPINB3 SERPINB4 HSPA4L PLA2G4E	1.14e-04	171	197	6	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 RYR1 LPAR5 FGD2 TEP1 EGFR	1.18e-04	172	197	6	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	TCGA-Head_and_Esophagus\|World / Sample_Type by Project: Shred V9	TENM2 SERPINB5 SERPINB3 SERPINB4 PLA2G4E ALOXE3	1.18e-04	172	197	6	eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 RYR1 LPAR5 FGD2 TEP1 EGFR	1.18e-04	172	197	6	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	NS-critical-d_16-33-Epithelial-Basal\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TPO S100A6 SERPINB5 SERPINB3 SERPINB4 DIAPH3	1.22e-04	173	197	6	3d3afc9ab234eaabf5b9bff455406231cd54ded6
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CREG2 GMPPA PLS1 MACC1 TG	1.22e-04	173	197	6	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TAGAP PIK3CA UTRN WDR49 DOP1B HIP1R	1.22e-04	173	197	6	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	facs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CREG2 GMPPA PLS1 MACC1 TG	1.25e-04	174	197	6	3b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like-MAIT\|Lung / Manually curated celltypes from each tissue	IL12RB2 TTC39C SPEG CARD10 FKBP11 SYNE2	1.29e-04	175	197	6	f6663e5a9c87e27f3459a6481768b03aff7d0855
ToppCell	droplet-Heart-HEART-1m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TAGAP C5AR1 FGD2 TEP1 IRAG2	1.29e-04	175	197	6	43b9cfd7c47d57244565c641e57f3256b5900804
ToppCell	facs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP11 CREG2 GMPPA PLS1 MACC1 TG	1.29e-04	175	197	6	4be01bf30331162f1998216fb2871a4e626dc440
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TAGAP C5AR1 FGD2 TEP1 IRAG2	1.29e-04	175	197	6	a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TAGAP C5AR1 FGD2 TEP1 IRAG2	1.33e-04	176	197	6	1df640f88667e2dad30e65279d6d33bba75024c1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 DIAPH3 UTRN EGFR SLCO1A2	1.33e-04	176	197	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 USP9Y S100A6 BTN2A2 UTRN MYO16	1.38e-04	177	197	6	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP85L GBP2 GBP3 SYNE2 UTRN N4BP1	1.38e-04	177	197	6	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP85L GBP2 GBP3 SYNE2 UTRN N4BP1	1.38e-04	177	197	6	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP85L GBP2 GBP3 SYNE2 UTRN N4BP1	1.38e-04	177	197	6	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like\|Lung / Manually curated celltypes from each tissue	IL12RB2 TTC39C SPEG CARD10 FKBP11 SYNE2	1.42e-04	178	197	6	bb5dc22f6bcde1ce29598ae4e839e98a7caa07b6
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 CCDC178 SNRNP25 CCDC160 TMEM121 IRAG2	1.42e-04	178	197	6	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-4\|TCGA-Breast / Sample_Type by Project: Shred V9	IL12RB2 MAP2 KCMF1 DIAPH3 ESYT3 MSLN	1.42e-04	178	197	6	44b5ba4e8788d3973749a1717e427647ac4c8579
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HK3 RYR1 BLM DIAPH3 SESTD1 POLA1	1.46e-04	179	197	6	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TPO ACACB NUAK1 SYNE2 UTRN FAT4	1.46e-04	179	197	6	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHH3 BLM DIAPH3 AP5M1 IRAG2 PEDS1	1.51e-04	180	197	6	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	S100A6 HIP1R TEP1 WDR91 GFM1 MSLN	1.55e-04	181	197	6	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 DIAPH3 MACC1 EGFR SLCO1A2	1.55e-04	181	197	6	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMSD S100A6 SERPINB5 C4BPA PLS1 MSLN	1.60e-04	182	197	6	cee5f1872d6464e380995323544a4cd567add370
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP2 LRRK2 HOXD3 TMEM164 SESTD1 RIMBP2	1.70e-04	184	197	6	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	IL12RB2 MYO7A RYR1 AP2A2 C5AR1 CFAP161	1.75e-04	185	197	6	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S100A6 SERPINB5 C4BPA CREG2 IRAG2 MSLN	1.75e-04	185	197	6	01d0e848d8ede2745cfb10b070e2d9674ef4d477
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 DIAPH3 MACC1 EGFR SLCO1A2	1.80e-04	186	197	6	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 SYNE2 DIAPH3 WDR91 PPP2R3A	1.80e-04	186	197	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PLS1 MACC1 HIP1R SLC2A1 ESYT3 RIMBP2	1.80e-04	186	197	6	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	TENM2 SERPINB5 SERPINB3 SERPINB4 PLA2G4E ALOXE3	1.85e-04	187	197	6	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CFAP54 SYNE2 DIAPH3 WDR91 PPP2R3A	1.85e-04	187	197	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC178 SLC22A6 HOXD3 SYNE2 PPP2R3A RIMBP2	1.85e-04	187	197	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAP2 DIAPH3 MACC1 SLCO1A2 MYO16 MSLN	1.91e-04	188	197	6	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TAGAP RYR1 C5AR1 LPAR5 FGD2 IRAG2	1.91e-04	188	197	6	8fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC178 HOXD3 MACC1 SLC2A1 PPP2R3A RIMBP2	1.91e-04	188	197	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	IL12RB2 RIN3 TAGAP NLRC3 TOGARAM2 IRAG2	1.96e-04	189	197	6	c604da558c9f4055fb36218452463539f2a73223
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB SYNE2 MGAM PPP2R3A EGFR RIMBP2	1.96e-04	189	197	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO7A LRRK2 RYR1 C5AR1 LPAR5 FGD2	1.96e-04	189	197	6	b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TAGAP RYR1 C5AR1 LPAR5 FGD2 IRAG2	2.02e-04	190	197	6	e5625feb21915d4545cfad2659745ef180efcb1f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 CCDC178 CFAP54 DIAPH3 MACC1 RIMBP2	2.02e-04	190	197	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	RIN3 LRRK2 STRADA C5AR1 UTRN TUT7	2.02e-04	190	197	6	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 SYNE2 UTRN CCDC160 EGFR SLCO1A2	2.02e-04	190	197	6	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTC39C LRRK2 TENM2 GPR26 RADIL MYO16	2.02e-04	190	197	6	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TTC39C LRRK2 TENM2 GPR26 RADIL MYO16	2.14e-04	192	197	6	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MYO7A TAGAP RYR1 LPAR5 FGD2 IRAG2	2.20e-04	193	197	6	2684fa361baaa9dc7a18a39ed11c0759e78e4418
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	TPO MAP2 SYNE2 UTRN KALRN MAP3K6	2.20e-04	193	197	6	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RYR1 SERPINB5 SERPINB3 SERPINB4 HSPA4L EGFR	2.20e-04	193	197	6	7c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	RIN3 HK3 AP2A2 C5AR1 FGD2 TG	2.20e-04	193	197	6	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	LRRK2 PIK3CA SESTD1 MACC1 FGD2 IRAG2	2.20e-04	193	197	6	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RIN3 HK3 LRRK2 S100A6 C5AR1 MGAM	2.26e-04	194	197	6	e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCell	BL-critical-LOC-Epithelial-Basal\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP2 SERPINB5 NUAK1 SERPINB3 SERPINB4 EGFR	2.26e-04	194	197	6	2932f704656ca368565ec12f3452af3b18e8df12
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TAGAP RYR1 C5AR1 LPAR5 FGD2 IRAG2	2.26e-04	194	197	6	846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCell	Mild/Remission-B_naive-8\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TAGAP PIK3CA UTRN WDR49 DOP1B HIP1R	2.32e-04	195	197	6	0a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TAGAP GBP2 RYR1 C5AR1 LPAR5 FGD2	2.32e-04	195	197	6	e8fb552f9ab77b656c27abc66af523b56cd9f9ad
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ACACB ACE AP5Z1 PLS1 WDR91 IQCC	2.32e-04	195	197	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 SPEG BCR TENM2 KCNJ13 MSLN	2.32e-04	195	197	6	0bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7-Slc17a6.Nptxr-Rorb_(Deep_layer_pyramidal_cells--Layer_5a)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	F2RL2 CFAP161 VWA5B1 CATSPERZ MACC1	2.34e-04	125	197	5	be820e4db3da737101f34ea9d2848a3ceb53f417
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TAGAP LRRK2 GBP2 C5AR1 MGAM PRKDC	2.39e-04	196	197	6	fe8d3f45a64323947c36b127355d5940eb56c0ca
Drug	NIH-3	BSN TG MAPK3 MAP2K5	1.83e-05	19	195	4	CID009822007
Drug	VAL-TRP	ACE MGAM ACE2	2.11e-05	7	195	3	CID000168182
Drug	3'-deoxy-ara-C	SERPINB3 SERPINB4 POLA1	3.36e-05	8	195	3	CID000122111
Drug	phenothrin	BLM RAD51D SESTD1 TG	3.38e-05	22	195	4	CID000004767
Drug	anti-O	BCR FASTK SERPINB3 SERPINB4 UMPS PEDS1	4.17e-05	74	195	6	CID000017345
Drug	PD184352	PIK3CA NELFB EGFR MAPK3 MAP2K5	4.51e-05	46	195	5	CID006918454
Drug	Clopamide [636-54-4]; Down 200; 11.6uM; HL60; HG-U133A	ACACA COPE PIDD1 PPME1 AP1G2 DMAC2 GTPBP1 N4BP1 MAP2K5	4.88e-05	195	195	9	1605_DN
Drug	Chlorogenic acid [327-97-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	ACACB PIDD1 S100A6 AP2A2 AP5Z1 GTPBP1 MAP3K6 IQCC MAP2K5	4.88e-05	195	195	9	3282_UP
Drug	CHEMBL1783187	INSRR ACE ACE2	5.00e-05	9	195	3	CID005230731
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; HL60; HG-U133A	PIDD1 HIRA AP2A2 FASTK UMPS MED7 DMAC2 ENTPD4 MAP2K5	5.29e-05	197	195	9	2022_UP
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A	DCAF1 TRPC5 PIDD1 CLPS APC ACE2 IQCC ALOXE3 MAP2K5	5.50e-05	198	195	9	4323_UP
Drug	Racecadotril [81110-73-8]; Down 200; 10.4uM; HL60; HG-U133A	ACACA FASTK RAB3GAP2 PPME1 TOM1L1 RANBP9 TTC27 THUMPD1 VPS13D	5.72e-05	199	195	9	1782_DN
Drug	BPIQ-I	BCR EGFR MAPK3	7.10e-05	10	195	3	CID000002427
Drug	bradykinin potentiator c	ACE ACE2	7.30e-05	2	195	2	CID004597608
Drug	isomartynoside	ACE ACE2	7.30e-05	2	195	2	CID006476337
Drug	2-nitrophenyl diethyl phosphate	ACE ACE2	7.30e-05	2	195	2	CID003014292
Drug	dansyltriglycine	ACE ACE2	7.30e-05	2	195	2	CID000194208
Drug	EU-4881	ACE ACE2	7.30e-05	2	195	2	CID000146389
Drug	A58365B	ACE ACE2	7.30e-05	2	195	2	CID000137366
Drug	A58365A	ACE ACE2	7.30e-05	2	195	2	CID000137365
Drug	spiromesifen	ACACA BSN	7.30e-05	2	195	2	CID009907412
Drug	AC1NNL9J	ACE ACE2	7.30e-05	2	195	2	CID005046512
Drug	I5b2	ACE ACE2	7.30e-05	2	195	2	CID000125070
Drug	Lisinopril	ACE ACE2	7.30e-05	2	195	2	DB00722
Drug	Moexipril	ACE ACE2	7.30e-05	2	195	2	DB00691
Drug	Ahtp-BK	ACE ACE2	7.30e-05	2	195	2	CID000128372
Drug	tebanyl	ACE ACE2	7.30e-05	2	195	2	CID000008609
Drug	CV-5975	ACE ACE2	7.30e-05	2	195	2	CID003035825
Drug	etioporphyrin	BLM MGAM	7.30e-05	2	195	2	CID000079013
Drug	EU-4865	ACE ACE2	7.30e-05	2	195	2	CID000132472
Drug	MDL 27,788	ACE ACE2	7.30e-05	2	195	2	CID005748412
Drug	EU-5031	ACE ACE2	7.30e-05	2	195	2	CID000194686
Drug	BRL 36378	ACE ACE2	7.30e-05	2	195	2	CID000134835
Drug	chlorambucyl-proline	ACE ACE2	7.30e-05	2	195	2	CID000133596
Drug	DU-1227	ACE ACE2	7.30e-05	2	195	2	CID000156284
Drug	Ketoace	ACE ACE2	7.30e-05	2	195	2	CID000156271
Drug	MDL27,467A	ACE ACE2	7.30e-05	2	195	2	CID000194915
Drug	AC1Q5QTP	ACE SLC22A6 ACE2 SLCO1A2	7.85e-05	27	195	4	CID000071324
Drug	dimethylmercury	TPO ACACA BCR SLC22A6 KCNJ13	8.21e-05	52	195	5	CID000011645
Disease	Sarcomatoid Renal Cell Carcinoma	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	1.74e-06	128	188	8	C1266043
Disease	Chromophobe Renal Cell Carcinoma	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	1.74e-06	128	188	8	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	1.74e-06	128	188	8	C1266044
Disease	Papillary Renal Cell Carcinoma	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	1.74e-06	128	188	8	C1306837
Disease	Renal Cell Carcinoma	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	1.74e-06	128	188	8	C0007134
Disease	Hereditary Diffuse Gastric Cancer	ACE PIK3CA UMPS FAT4 APC BIRC2 MAP3K6 NBAS EGFR MAPK3 MSLN	3.13e-06	293	188	11	C1708349
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	LRRK2 PIDD1 FPGT RYR1 PIK3CA SYNE2 SLC2A1 AP5M1	5.15e-06	148	188	8	C0279702
Disease	Squamous cell carcinoma	BLM PIK3CA SERPINB3 UMPS EGFR PRKDC MAPK3	1.53e-05	124	188	7	C0007137
Disease	Stomach Neoplasms	ACE PIK3CA UMPS FAT4 APC BIRC2 NBAS EGFR MAPK3 MSLN	2.26e-05	297	188	10	C0038356
Disease	Malignant neoplasm of stomach	ACE PIK3CA UMPS FAT4 APC BIRC2 NBAS EGFR MAPK3 MSLN	2.47e-05	300	188	10	C0024623
Disease	lung disease (biomarker_via_orthology)	ACE C5AR1 ACE2 EGFR	7.16e-05	35	188	4	DOID:850 (biomarker_via_orthology)
Disease	Carcinoma, Granular Cell	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0205644
Disease	Adenocarcinoma, Tubular	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0205645
Disease	Adenocarcinoma, Oxyphilic	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0205642
Disease	Carcinoma, Cribriform	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0205643
Disease	Adenocarcinoma, Basal Cell	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0205641
Disease	Adenocarcinoma	ACE PIK3CA FAT4 APC EGFR MSLN	1.03e-04	116	188	6	C0001418
Disease	infantile liver failure syndrome (is_implicated_in)	TRMU NBAS	1.21e-04	3	188	2	DOID:0080716 (is_implicated_in)
Disease	Malignant Neoplasms	BLM PIK3CA NACC1 APC EGFR MSLN	1.76e-04	128	188	6	C0006826
Disease	Malignant Head and Neck Neoplasm	FANCB PIK3CA EGFR MAPK3	1.78e-04	44	188	4	C0278996
Disease	schizophrenia (is_marker_for)	MAP2 ACE EGFR MAPK3	1.78e-04	44	188	4	DOID:5419 (is_marker_for)
Disease	ovarian neoplasm	PIK3CA RAD51D SLC2A1 EGFR MAPK3 MSLN	2.26e-04	134	188	6	C0919267
Disease	Myopathy, Centronuclear, Autosomal Recessive	SPEG RYR1	2.40e-04	4	188	2	C0410204
Disease	Malignant neoplasm of ovary	PIK3CA RAD51D SLC2A1 EGFR MAPK3 MSLN	2.54e-04	137	188	6	C1140680
Disease	COVID-19 (is_implicated_in)	ACE C4BPA ACE2	3.11e-04	21	188	3	DOID:0080600 (is_implicated_in)
Disease	Adenocarcinoma of lung (disorder)	INSRR FKBP11 PIK3CA FASTK APC EGFR PRKDC	3.70e-04	206	188	7	C0152013
Disease	quality of life during menstruation measurement, Arthralgia	GAD2 DOP1B	3.99e-04	5	188	2	EFO_0009366, HP_0002829
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	3.99e-04	5	188	2	DOID:0080000 (implicated_via_orthology)
Disease	Immunologic Deficiency Syndromes	BLM EPG5 NBAS	4.10e-04	23	188	3	C0021051
Disease	Thyroid Dyshormonogenesis 1	TPO TG	5.96e-04	6	188	2	C1848805
Disease	Colorectal Carcinoma	HK3 ACACA MAP2 SERPINB5 PIK3CA UMPS TMEM164 WDR49 KALRN ABCB5 APC EGFR SLCO1A2	6.02e-04	702	188	13	C0009402
Disease	urate measurement, bone density	WDR64 GBP3 TENM2 MOV10L1 UTRN PMPCB ABCB5 ENTPD4 TG USP14 PRKDC MYO16	6.56e-04	619	188	12	EFO_0003923, EFO_0004531
Disease	Glioblastoma Multiforme	INSRR PIK3CA APC EGFR STAG2	7.39e-04	111	188	5	C1621958
Disease	primary biliary cholangitis (biomarker_via_orthology)	ACE ACE2 SLCO1A2	7.42e-04	28	188	3	DOID:12236 (biomarker_via_orthology)
Disease	Goiter	TPO TG	8.30e-04	7	188	2	C0018021
Disease	Rectal Neoplasms	APC EGFR	8.30e-04	7	188	2	C0034885
Disease	Rectal Carcinoma	APC EGFR	8.30e-04	7	188	2	C0007113
Disease	fatty liver disease (implicated_via_orthology)	ACACA ACACB LRP6	1.00e-03	31	188	3	DOID:9452 (implicated_via_orthology)
Disease	sialic acid-binding Ig-like lectin 12 measurement	UMPS KALRN	1.10e-03	8	188	2	EFO_0802066
Disease	stomach cancer (is_implicated_in)	ACE PIK3CA APC TEP1	1.17e-03	72	188	4	DOID:10534 (is_implicated_in)
Disease	Head and Neck Neoplasms	PIK3CA EGFR MAPK3	1.21e-03	33	188	3	C0018671
Disease	HEPATOCELLULAR CARCINOMA	PIK3CA APC	1.41e-03	9	188	2	114550
Disease	ureteral obstruction (implicated_via_orthology)	ACE MAPK3	1.41e-03	9	188	2	DOID:5199 (implicated_via_orthology)
Disease	Spastic Paraplegia	RAB3GAP2 SLC2A1	1.41e-03	9	188	2	C0037772
Disease	Hepatocellular carcinoma	PIK3CA APC	1.41e-03	9	188	2	cv:C2239176
Disease	vesicular integral-membrane protein VIP36 measurement	UMPS KALRN	1.76e-03	10	188	2	EFO_0022012
Disease	thrombosis (implicated_via_orthology)	C5AR1 ACE2	1.76e-03	10	188	2	DOID:0060903 (implicated_via_orthology)
Disease	Head and Neck Carcinoma	PIK3CA EGFR	1.76e-03	10	188	2	C3887461
Disease	2-aminobutyrate measurement	EPG5 LRRC28	1.76e-03	10	188	2	EFO_0020017
Disease	lifestyle measurement, anxiety disorder measurement	WDR64 TTC39C CCDC178 CFAP54 TTC27	1.89e-03	137	188	5	EFO_0007795, EFO_0010724
Disease	Gastric cancer	PIK3CA APC	2.14e-03	11	188	2	cv:C0024623
Disease	Neoplasm of stomach	PIK3CA APC	2.14e-03	11	188	2	cv:C0038356
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	ACE PIK3CA	2.14e-03	11	188	2	DOID:0110861 (biomarker_via_orthology)
Disease	Pancreatic Ductal Adenocarcinoma	ACACB ABCB5	2.14e-03	11	188	2	C1335302
Disease	GASTRIC CANCER	PIK3CA APC	2.14e-03	11	188	2	613659
Disease	Mesothelioma	APC EGFR MSLN	2.27e-03	41	188	3	C0025500
Disease	sleep duration	MAP2 OR13F1 TENM2 NALCN USP49 GTPBP1 PPP2R3A PIWIL3	2.34e-03	362	188	8	EFO_0005271
Disease	Glioma	PIK3CA APC EGFR STAG2	2.35e-03	87	188	4	C0017638
Disease	Childhood Medulloblastoma	S100A6 STRADA APC	2.60e-03	43	188	3	C0278510
Disease	Melanotic medulloblastoma	S100A6 STRADA APC	2.60e-03	43	188	3	C1275668
Disease	Medullomyoblastoma	S100A6 STRADA APC	2.60e-03	43	188	3	C0205833
Disease	Desmoplastic Medulloblastoma	S100A6 STRADA APC	2.60e-03	43	188	3	C0751291
Disease	Adult Medulloblastoma	S100A6 STRADA APC	2.60e-03	43	188	3	C0278876
Disease	Colonic Neoplasms	SERPINB5 UMPS APC SLC2A1 EGFR	2.96e-03	152	188	5	C0009375
Disease	Congenital Hypothyroidism	TPO TG	3.01e-03	13	188	2	C0010308
Disease	leukemia (is_implicated_in)	ACE BCR	3.01e-03	13	188	2	DOID:1240 (is_implicated_in)
Disease	Paroxysmal atrial fibrillation	ACE SYNE2 HERC1 HIP1R PPP2R3A	3.31e-03	156	188	5	C0235480
Disease	familial atrial fibrillation	ACE SYNE2 HERC1 HIP1R PPP2R3A	3.31e-03	156	188	5	C3468561
Disease	Persistent atrial fibrillation	ACE SYNE2 HERC1 HIP1R PPP2R3A	3.31e-03	156	188	5	C2585653
Disease	Adenocarcinoma of large intestine	PIK3CA APC EGFR PRKDC	3.36e-03	96	188	4	C1319315
Disease	response to methotrexate, aspartate aminotransferase measurement	MAP2 RIMBP2	3.49e-03	14	188	2	EFO_0004736, GO_0031427
Disease	Neoplasm of lung	PIK3CA EGFR	3.49e-03	14	188	2	cv:C0024121
Disease	congenital hypothyroidism (implicated_via_orthology)	TPO TG	3.49e-03	14	188	2	DOID:0050328 (implicated_via_orthology)
Disease	bipolar disorder, response to lithium ion	SESTD1 EGFR	3.49e-03	14	188	2	GO_0010226, MONDO_0004985
Disease	Lung cancer	PIK3CA EGFR	3.49e-03	14	188	2	cv:C0242379
Disease	LUNG CANCER	PIK3CA EGFR	3.49e-03	14	188	2	211980
Disease	Malignant tumor of colon	SERPINB5 UMPS APC SLC2A1 EGFR	3.59e-03	159	188	5	C0007102
Disease	Atrial Fibrillation	ACE SYNE2 HERC1 HIP1R PPP2R3A	3.69e-03	160	188	5	C0004238
Disease	corpus callosum volume measurement	TTC39C NUAK1 TG EGFR	3.89e-03	100	188	4	EFO_0010299
Disease	Medulloblastoma	S100A6 STRADA APC	4.00e-03	50	188	3	C0025149
Disease	3-hydroxyanthranilic acid measurement	CREG2 TG	4.01e-03	15	188	2	EFO_0010447
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG RYR1	4.01e-03	15	188	2	C3645536
Disease	Weight Gain	ACE PIK3CA SESTD1 VPS13D	4.17e-03	102	188	4	C0043094
Disease	pancreatic ductal carcinoma (is_implicated_in)	MAPK3 MSLN	4.57e-03	16	188	2	DOID:3587 (is_implicated_in)
Disease	Polyposis, Adenomatous Intestinal	APC EGFR	4.57e-03	16	188	2	C2713442
Disease	Familial Intestinal Polyposis	APC EGFR	4.57e-03	16	188	2	C2713443
Disease	Major Depressive Disorder	GAD2 MAP2 ACE BCR KALRN EGFR	4.79e-03	243	188	6	C1269683
Disease	Mouth Neoplasms	PIK3CA SERPINB3 UMPS	4.97e-03	54	188	3	C0026640
Disease	Malignant neoplasm of mouth	PIK3CA SERPINB3 UMPS	4.97e-03	54	188	3	C0153381
Disease	Benign neoplasm of stomach	PIK3CA APC	5.16e-03	17	188	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	PIK3CA APC	5.16e-03	17	188	2	C0496905
Disease	Carcinoma in situ of stomach	PIK3CA APC	5.16e-03	17	188	2	C0154060
Disease	Adenomatous Polyposis Coli	APC EGFR	5.16e-03	17	188	2	C0032580
Disease	leukemia	BLM BIRC2 STAG2	5.24e-03	55	188	3	C0023418
Disease	Early Pregnancy Loss	MAP2 SERPINB3 SERPINB4 ACE2	5.28e-03	109	188	4	C3830362
Disease	Spontaneous abortion	MAP2 SERPINB3 SERPINB4 ACE2	5.28e-03	109	188	4	C0000786
Disease	Miscarriage	MAP2 SERPINB3 SERPINB4 ACE2	5.28e-03	109	188	4	C4552766
Disease	Abortion, Tubal	MAP2 SERPINB3 SERPINB4 ACE2	5.28e-03	109	188	4	C0000822
Disease	hippocampal atrophy	S100A6 TTC27 MROH8	5.51e-03	56	188	3	EFO_0005039
Disease	coronary artery disease, factor VII measurement	CNNM2 NBEAL1 UMPS PMPCB	5.63e-03	111	188	4	EFO_0001645, EFO_0004619

Protein segments in the cluster

Peptide	Gene	Start	Entry
QIIRCSLEGLMELNG	TDRD1	1051	Q9BXT4
MTLIAALLPAVLGNC	C4BPA	36	P04003
LSQAQLNMPLSEVCE	CATSPERZ	36	Q9NTU4
QECALGMLEVPLCQI	ESYT3	536	A0FGR9
LLMQSSAEQLLSPEC	EPG5	1836	Q9HCE0
LTGQEPAQRCSMILD	CARD10	111	Q9BWT7
IGGINLNCMLTSLPN	CFAP54	736	Q96N23
INNISLMTLGVPCTA	ACER2	146	Q5QJU3
GSCLQLEPDLTNVMA	ACE	761	P12821
ESCMLNLLLSLPEAN	BCR	1161	P11274
QHECIPQAILGMDVL	DDX39A	71	O00148
PLVLGEMSDNLISGC	ABCB5	66	Q2M3G0
DMCPANILQETLKLL	GTPBP1	311	O00178
LLVTLEDINDNGPML	FAT4	3496	Q6V0I7
IQPVQGLALCTLSTM	AP1G2	116	O75843
VTMLIDQLCGRDPTL	ACACA	1041	Q13085
QEMADKCSPTLLLLN	COPE	206	O14579
QLQVLCAAILREMSP	AP5Z1	81	O43299
GLTQILVEEMLPNCE	DMAC2	216	Q9NW81
LRGDLSLCMTPDEIQ	CFAP161	86	Q6P656
GAACSILPSLILLNM	C5AR1	106	P21730
CMQLINALVTSPDDL	DIAPH3	341	Q9NSV4
EDPRCVQLTLTGQMI	CREG2	211	Q8IUH2
IGCLLRLEPNLQAQM	AP2A2	901	O94973
CQESDMADLPGNILL	NBEAL1	816	Q6ZS30
PLALAMGQATQCLGL	RANBP9	696	Q96S59
VGLCPGLTEEMIQLL	RAD51D	6	O75771
GTCLLQMKILEDQTP	IQCC	311	Q4KMZ1
GEVLENMLKASCLPL	NCLN	6	Q969V3
ASSNLVPSLLGLCMI	PPME1	166	Q9Y570
LRLEENCLELSMLPQ	LRRC57	181	Q8N9N7
NCLELSMLPQSILSD	LRRC57	186	Q8N9N7
LASCAMADLVPDLQP	RADIL	491	Q96JH8
NQLVIMLIDELCGPD	ACACB	1181	O00763
QDCVLSLSPTNDLMV	RAB3GAP2	76	Q9H2M9
APLATVNILMSLCQL	FASTK	311	Q14296
TNMLLQLDGSTPICE	PMPCB	406	O75439
PMLCSNAQEIELLSI	OR8K5	186	Q8NH50
LNTAACRLLLDIMPG	DCAF1	101	Q9Y4B6
PLQCSALLVREEGLM	GAD2	401	Q05329
ETQLSVLPLQGCGLM	IGDCC3	746	Q8IVU1
CLIPLGLMSDISGQI	MOV10L1	896	Q9BXT6
SLIDDQGMPKNCLLI	MAGEC3	536	Q8TD91
VMVLLAGANCVLDPL	LPAR5	281	Q9H1C0
VCLEQMFPEDQALLG	NLRC3	296	Q7RTR2
GCAILMTIALALLEQ	SLC2A1	346	P11166
QMALVPCVLTLNQDG	TRMU	336	O75648
LDIPGMEECLNIASS	MTMR9	81	Q96QG7
MEIDQCLLESLPLGQ	MYO16	1	Q9Y6X6
NPLRSDGMNILCDAL	NLRP11	756	P59045
NDMVAPLLGQDTCLQ	ALOXE3	301	Q9BYJ1
LGCLVQPLAEDMEAL	DOP1B	506	Q9Y3R5
TLCMESQQILPDGSL	MGAM	1461	O43451
IEMIQNCLASLPDDL	MED7	161	O43513
SMLCQIVNSLLLLPV	HERC1	1061	Q15751
CQIMPELAHGLSELL	HECTD2	556	Q5U5R9
SLPTRINIMNLCEAG	IL12RB2	406	Q99665
INIMNLCEAGLLAPR	IL12RB2	411	Q99665
ALDLTGMRPESQLAC	BSN	1886	Q9UPA5
CAMSLAELQEPLLQL	CCDC178	576	Q5BJE1
DGVLMELQDCALPLL	MDH1	51	P40925
MTNNVLLCSQADLPD	MAP3K6	141	O95382
GNLLCTVVNMPLTLA	GPR26	51	Q8NDV2
DMAPLLQENSRLGCQ	FDX2	141	Q6P4F2
DGILLCKMINLSEPD	PLS1	161	Q14651
LMPLQLLQCIVDEDS	MAP2K5	366	Q13163
EDLLSIIANMSGCLP	TPO	121	P07202
ITLKICNLMPQDSGI	KALRN	2531	O60229
LQDRASCLPAMLLDP	NSUN5P2	26	Q63ZY6
CPSAIALLAIQMLLG	KCNJ13	131	O60928
NGDNCLVTLLPLLNM	PEDS1	136	A5PLL7
QVLGDLSMILCDPFA	NELFB	296	Q8WX92
LVNLNEDPLMSECLL	KIF1C	501	O43896
PMHLVLLQDELSCGE	LRP6	1231	O75581
SLAIPCNNVEVLMSG	LRRK2	231	Q5S007
LNIGNVSTPLMCLSE	LRRK2	2291	Q5S007
QPTNCMALLTGSLVL	DSE	206	Q9UL01
DLPCMENAVLALAQI	GBP2	306	P32456
DLPCMENAVLALAQI	GBP3	306	Q9H0R5
VLDLSMQEALSGTPC	MSLN	596	Q13421
LGSPSQEDLNCIINM	MAPK3	261	P27361
CDLEGIMPNVTISLS	AP5M1	241	Q9H0R1
MLFEQGQQALELPEC	HOXD3	1	P31249
PRGIIINLENGELCM	CLPS	21	P04118
MGVICAQLSIISQPR	MROH8	386	Q9H579
QGTVMLLAPECDVSL	HK3	441	P52790
MERNIPGLLVLCDNL	NBAS	871	A2RRP1
LLCQMLDLVKPAVDG	PPP2R3A	1021	Q06190
MCELNVLPLALQITN	POLA1	756	P09884
LVECLLPNGMIVTLE	PIK3CA	21	P42336
LPNGMIVTLECLREA	PIK3CA	26	P42336
LMGNCLIILVTLADP	OR10A2	26	Q9H208
LLLLLPTFCQSGMEN	F2RL2	11	O00254
TVLLQIMERESGNCP	FANCB	596	Q8NB91
SQPLDCLSDGQVMTL	PLA2G4E	296	Q3MJ16
IEACAQVPGMQEILL	GMPPA	41	Q96IJ6
VQLITQLMPFGCLLD	EGFR	786	P00533
MSSGQCRLAPLIQVI	HIP1R	206	O75146
QVIPGLEQSLLDMCV	FKBP11	91	Q9NYL4
INAALLGEDCFILMP	BLM	676	P54132
LLPVASQMEASCLVI	FAAP24	116	Q9BTP7
NLLILMIPNFTDQDC	AXDND1	711	Q5T1B0
MSPKLCLNLLNEELE	CCDC160	141	A6NGH7
LLMNLGPENCATLLL	DENND4C	396	Q5VZ89
CLLLEPGLNEIMANS	ACE2	141	Q9BYF1
EPNLSLLLGIRSMNC	CEP85L	741	Q5SZL2
SCTVSPLLEIMLGNL	MACC1	266	Q6ZN28
LEELEGCPLQLQELM	INSRR	1211	P14616
TPDQSLMCSFLQLIG	FGD2	541	Q7Z6J4
SDPGLEILNMASCDL	IRAG2	101	Q12912
GCVDIMPLDVALENL	KCMF1	351	Q9P0J7
TELTLNMCLELPTGS	HMSD	16	P0C7T4
LNIPEINSLITTDMC	DCLRE1A	911	Q6PJP8
IDPIAGMAITLNCEL	ETFBKMT	146	Q8IXQ9
GMAITLNCELNRLNP	ETFBKMT	151	Q8IXQ9
SQDAMLCSGPLAIIQ	HIRA	876	P54198
NPILAMVGENTTLRC	BTN2A2	41	Q8WVV5
QALANATLCILEPIM	GFM1	636	Q96RP9
LLIPQLCHMTGLTDE	PIWIL3	396	Q7Z3Z3
EDCGIMDSQLSAILP	PRAMEF8	356	Q5VWM4
PAQMAALLLAGICIL	SLC22A6	396	Q4U2R8
GLNMCAPTDQDLITL	RYR1	3521	P21817
MNPGILVTCADDIEL	FPGT	171	O14772
SLETLPACVLQMRGL	PIDD1	136	Q9HB75
APLENAELCTQAMAL	RIN3	476	Q8TB24
ECALMLLQHGTDPNL	POTEA	146	Q6S8J7
MSVLPLSLCGNSIIN	OR13F1	161	Q8NGS4
GILPQSLDLLLCINM	METTL26	96	Q96S19
GPTEMCDQRQLGLLL	UTRN	2981	P46939
SCLMLLSQVQGEEPQ	REG3A	16	Q06141
ARLGLIPCNMVSEIQ	RIMBP2	901	O15034
QMLLEKLNGTVPCLL	STRADA	286	Q7RTN6
LTLSLIDMCVQNCGP	TOM1L1	71	O75674
LMQGVLQTCRDLPAL	PLEKHH3	286	Q7Z736
SLQLPEGLCLMQTVF	PRDM14	246	Q9GZV8
MACPLDQAIGLLVAI	S100A6	1	P06703
SNLAICIGPNMLTLE	TAGAP	231	Q8N103
CIGPNMLTLENDQSL	TAGAP	236	Q8N103
SMILLENQIGCLTPE	SYNE2	1796	Q8WXH0
LDAMVESLDNLCLLP	TOGARAM2	871	Q6ZUX3
NMNTQLPTLLIAECV	LCMT1	186	Q9UIC8
LCQLPSLNELSMAGN	LRRC28	176	Q86X40
LQLCPRLAMLTLEGN	LRRC56	181	Q8IYG6
AVLEGMPALESLCLQ	FBXL12	246	Q9NXK8
ILCTAGMRILPESQQ	ENTPD4	176	Q9Y227
VQGMCDLLAPLLVTL	SGSM2	836	O43147
NCSLITGQDLLSVPM	SIX4	666	Q9UIU6
QSLPAEVGCLVNLMT	SHOC2	136	Q9UQ13
CVEGMNLPLLEQAIR	TEN1	96	Q86WV5
CNISLPMENGLNSIE	TENM2	1806	Q9NT68
MGNIDSINCKIIELP	SERPINB5	206	P36952
MEQDLCRTGVLLPSS	NUAK1	431	O60285
CLMGTVGTLLLENPL	IARS1	1186	P41252
LCMENGTQILRPTQD	SLCO1A2	131	P46721
LSMIVLLPNEIDGLQ	SERPINB3	241	P29508
GLILTIPLCLEQTNM	SESTD1	26	Q86VW0
MALFQQLTCVLPILD	BIRC2	466	Q13490
SMRQSGCLPLLIQLL	APC	346	P25054
MSPLLGLRSELQDTC	AQP11	1	Q8NBQ7
DSCLPLGMSQEDNQL	CLP1	336	Q92989
TDDLLQLLMSCPQVE	CLHC1	461	Q8NHS4
QLLMSCPQVELIQCL	CLHC1	466	Q8NHS4
ALDPMELRIVQNCGT	CNNM2	281	Q9H8M5
EDCGIMDSQLSAILP	PRAMEF7	356	Q5VXH5
CGNPISMATLENLLS	PRAMEF6	386	Q5VXH4
PLNIFCLTDMQLICG	TRIM13	101	O60858
SLENRCLAMLPDLQP	TEP1	16	Q99973
LAKEAMLECQVTGLP	SPEG	1201	Q15772
VPRCLLLGTDMAENQ	PYROXD2	131	Q8N2H3
LLNIESQCIMLSEGI	SMC1B	741	Q8NDV3
ECMNSLLLEEPLSGE	STAG2	496	Q8N3U4
LMSANASDLPLNIEC	HSPA4L	276	O95757
ILGLVTEVNLNNMLC	TMEM164	226	Q5U3C3
LLVLPCVALSEVSMQ	TMEM121	191	Q9BTD3
ETEGLTCQVCQMLLP	ZNF592	736	Q92610
LEMCEPGGQLLIISS	WDR49	481	Q8IV35
CGNPISMATLENLLS	PRAMEF5	386	Q5TYX0
EGLAMVVQDPLLCDL	SNRNP25	6	Q9BV90
FVPLNQTECLLTEML	USP49	486	Q70CQ1
LLQLADALGPSICML	UMPS	266	P11172
GICLPDLSVTSMLEQ	ZNF534	61	Q76KX8
LSMIVLLPNEIDGLQ	SERPINB4	241	P48594
LQLDPSLLTENGMKC	USP9Y	726	O00507
SINLPMSCLDSIALG	MAP2	701	P11137
CLMDQATDPNILGRT	PRKDC	4106	P78527
LLDMLQALCIPTFQL	TNPO3	721	Q9Y5L0
VNINCMDPLGRSALL	TRPC5	61	Q9UL62
PLQDAELALAGINML	TTC39C	26	Q8N584
AIMSQPDVLLLVQEC	TUT7	361	Q5VYS8
PLLFTLAENCIDQVM	TTC27	201	Q6P3X3
QLASAMELPCGLTNL	USP14	96	P54578
INDNMPRILSLACSP	WDR91	491	A4D1P6
IMESNAQGCRLILPQ	TG	1931	P01266
IEDMDPELQQLLACG	XIRP1	871	Q702N8
PGLQGILITCNMNER	THUMPD1	41	Q9NXG2
CLATLLNTEVSNPME	VWA5B1	206	Q5TIE3
PTMDLLRVNCIDLLQ	WDR64	641	B1ANS9
LVSCATEIGPQALMN	ZSWIM4	696	Q9H7M6
CTLLGDLPQMELQEA	VPS13D	211	Q5THJ4
LAPSNCLGMIRLSEI	KLHL38	131	Q2WGJ6
VPAESGAQLLMVLRC	NALCN	976	Q8IZF0
QMEIPNFGNSILECL	NACC1	6	Q96RE7
CLRDMQPLLSALPNV	N4BP1	776	O75113
ASLLEVNPPDLMSCL	MYO7A	356	Q13402