Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	8.76e-06	372	56	8	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	1.43e-05	398	56	8	GO:0061659
GeneOntologyMolecularFunction	pancreatic polypeptide receptor activity	NPY4R2 NPY4R	4.62e-05	4	56	2	GO:0001602
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	4.89e-05	473	56	8	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	8.52e-05	512	56	8	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	1.11e-04	532	56	8	GO:0016755
GeneOntologyMolecularFunction	growth hormone receptor binding	JAK1 JAK2	3.43e-04	10	56	2	GO:0005131
GeneOntologyMolecularFunction	neuropeptide Y receptor activity	NPY4R2 NPY4R	4.18e-04	11	56	2	GO:0004983
GeneOntologyMolecularFunction	zinc ion binding	TRAF7 UBR1 TUT4 TRIM73 SAMHD1 TRIM50 TRIM44 SHANK3 TRIM74	7.73e-04	891	56	9	GO:0008270
GeneOntologyMolecularFunction	acyltransferase activity	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM44 TRIM74	1.36e-03	775	56	8	GO:0016746
GeneOntologyMolecularFunction	transition metal ion binding	TRAF7 UBR1 TUT4 TRIM73 PIM1 SAMHD1 TRIM50 TRIM44 SHANK3 TRIM74	1.56e-03	1189	56	10	GO:0046914
GeneOntologyBiologicalProcess	cellular response to interleukin-6	JAK1 JAK2 TRAF7 TUT4	5.77e-06	45	54	4	GO:0071354
GeneOntologyBiologicalProcess	response to interleukin-6	JAK1 JAK2 TRAF7 TUT4	8.14e-06	49	54	4	GO:0070741
GeneOntologyBiologicalProcess	protein ubiquitination	NHLRC1 MKRN4P TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM44 TRIM74	4.16e-05	811	54	10	GO:0016567
GeneOntologyBiologicalProcess	interleukin-6-mediated signaling pathway	JAK1 JAK2 TUT4	5.31e-05	28	54	3	GO:0070102
GeneOntologyBiologicalProcess	post-translational protein modification	NHLRC1 MKRN4P JAK2 TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM44 TRIM74	8.80e-05	1074	54	11	GO:0043687
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	NHLRC1 MKRN4P TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM44 TRIM74	9.31e-05	893	54	10	GO:0032446
GeneOntologyBiologicalProcess	response to cytokine	JAK1 JAK2 TRAF7 TUT4 PIM1 IL17RC SAMHD1 DCSTAMP TRIM44 SHANK3 LGALS9	9.48e-05	1083	54	11	GO:0034097
GeneOntologyBiologicalProcess	response to peptide	JAK1 JAK2 TRAF7 TUT4 PIM1 IL17RC SAMHD1 DCSTAMP TRIM44 SHANK3 LGALS9	1.09e-04	1100	54	11	GO:1901652
GeneOntologyBiologicalProcess	response to interleukin-3	JAK1 JAK2	1.40e-04	7	54	2	GO:0036015
GeneOntologyBiologicalProcess	cellular response to interleukin-3	JAK1 JAK2	1.40e-04	7	54	2	GO:0036016
GeneOntologyBiologicalProcess	cellular response to cytokine stimulus	JAK1 JAK2 TRAF7 TUT4 PIM1 IL17RC SAMHD1 DCSTAMP TRIM44 LGALS9	1.79e-04	967	54	10	GO:0071345
GeneOntologyBiologicalProcess	cellular response to type II interferon	JAK1 JAK2 PIM1 LGALS9	2.26e-04	114	54	4	GO:0071346
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	NHLRC1 MKRN4P TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM44 TRIM74	2.52e-04	1009	54	10	GO:0070647
GeneOntologyBiologicalProcess	growth hormone receptor signaling pathway via JAK-STAT	JAK1 JAK2	2.99e-04	10	54	2	GO:0060397
GeneOntologyCellularComponent	inclusion body	TRIM73 TRIM50 WDFY3 TRIM74	8.62e-05	90	54	4	GO:0016234
GeneOntologyCellularComponent	Atg12-Atg5-Atg16 complex	WDFY3 ATG16L2	9.76e-05	6	54	2	GO:0034274
GeneOntologyCellularComponent	aggresome	TRIM73 TRIM50 TRIM74	1.50e-04	40	54	3	GO:0016235
MousePheno	hypochlorhydria	TRIM73 TRIM50 TRIM74	8.75e-07	7	42	3	MP:0008001
MousePheno	increased stomach pH	TRIM73 TRIM50 TRIM74	1.67e-05	17	42	3	MP:0008006
MousePheno	abnormal stomach pH	TRIM73 TRIM50 TRIM74	2.36e-05	19	42	3	MP:0008004
MousePheno	abnormal gastric parietal cell morphology	TRIM73 TRIM50 TRIM74	6.25e-05	26	42	3	MP:0004139
MousePheno	abnormal gastric gland morphology	TRIM73 TRIM50 TRIM74	1.41e-04	34	42	3	MP:0003892
MousePheno	abnormal digestive secretion	TRIM73 TRIM50 TRIM74	1.54e-04	35	42	3	MP:0000501
Domain	Znf-RING_LisH	TRAF7 TRIM73 TRIM50 TRIM74	2.71e-06	34	54	4	IPR027370
Domain	zf-RING_UBOX	TRAF7 TRIM73 TRIM50 TRIM74	2.71e-06	34	54	4	PF13445
Domain	NPY4_rcpt	NPY4R2 NPY4R	8.21e-06	2	54	2	IPR001933
Domain	ZF_RING_1	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM74	1.96e-05	291	54	7	PS00518
Domain	ZF_RING_2	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM74	2.29e-05	298	54	7	PS50089
Domain	Znf_RING	NHLRC1 MKRN4P TRAF7 UBR1 TRIM73 TRIM50 TRIM74	4.05e-05	326	54	7	IPR001841
Domain	-	NHLRC1 TRAF7 UBR1 TRIM73 ZFYVE26 TRIM50 WDFY3 TRIM74	4.14e-05	449	54	8	3.30.40.10
Domain	BBOX	TRIM73 TRIM50 TRIM44 TRIM74	4.69e-05	69	54	4	SM00336
Domain	Znf_RING/FYVE/PHD	NHLRC1 TRAF7 UBR1 TRIM73 ZFYVE26 TRIM50 WDFY3 TRIM74	4.83e-05	459	54	8	IPR013083
Domain	Tyr_kinase_non-rcpt_Jak/Tyk2	JAK1 JAK2	4.90e-05	4	54	2	IPR016251
Domain	-	TRIM73 TRIM50 TRIM44 TRIM74	5.25e-05	71	54	4	4.10.45.10
Domain	zf-B_box	TRIM73 TRIM50 TRIM44 TRIM74	5.55e-05	72	54	4	PF00643
Domain	-	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	7.82e-05	248	54	6	1.25.40.20
Domain	ArfGap	ARFGAP2 ACAP3 AGAP2	7.92e-05	29	54	3	SM00105
Domain	ArfGap	ARFGAP2 ACAP3 AGAP2	7.92e-05	29	54	3	PF01412
Domain	ARFGAP	ARFGAP2 ACAP3 AGAP2	7.92e-05	29	54	3	PS50115
Domain	ArfGAP	ARFGAP2 ACAP3 AGAP2	7.92e-05	29	54	3	IPR001164
Domain	ANK	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	8.35e-05	251	54	6	SM00248
Domain	ZF_BBOX	TRIM73 TRIM50 TRIM44 TRIM74	8.39e-05	80	54	4	PS50119
Domain	ANK_REPEAT	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	8.73e-05	253	54	6	PS50088
Domain	Znf_B-box	TRIM73 TRIM50 TRIM44 TRIM74	8.80e-05	81	54	4	IPR000315
Domain	Ankyrin_rpt-contain_dom	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	8.92e-05	254	54	6	IPR020683
Domain	ANK_REP_REGION	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	8.92e-05	254	54	6	PS50297
Domain	Ankyrin_rpt	ASB18 ASB10 DGKZ SHANK3 ACAP3 AGAP2	1.06e-04	262	54	6	IPR002110
Domain	Znf_RING_CS	NHLRC1 TRAF7 TRIM73 TRIM50 TRIM74	1.07e-04	163	54	5	IPR017907
Domain	PH_dom-like	JAK1 JAK2 CNKSR1 PLEKHS1 WDFY3 ACAP3 AGAP2	2.15e-04	426	54	7	IPR011993
Domain	RING	NHLRC1 MKRN4P TRAF7 TRIM73 TRIM50 TRIM74	2.41e-04	305	54	6	SM00184
Domain	NPY_rcpt	NPY4R2 NPY4R	2.92e-04	9	54	2	IPR000611
Domain	Ank_2	ASB18 ASB10 DGKZ SHANK3 AGAP2	3.86e-04	215	54	5	PF12796
Domain	zf-C3HC4	MKRN4P TRAF7 TRIM73 TRIM50 TRIM74	4.56e-04	223	54	5	PF00097
Domain	Ank	ASB18 ASB10 DGKZ ACAP3 AGAP2	5.04e-04	228	54	5	PF00023
Domain	PDEase_catalytic_dom	SAMHD1 PDE11A	2.00e-03	23	54	2	IPR002073
Domain	SAM	CNKSR1 SAMHD1 SHANK3	2.11e-03	88	54	3	SM00454
Domain	HDc	SAMHD1 PDE11A	2.17e-03	24	54	2	SM00471
Domain	HD/PDEase_dom	SAMHD1 PDE11A	2.17e-03	24	54	2	IPR003607
Domain	SAM_DOMAIN	CNKSR1 SAMHD1 SHANK3	2.62e-03	95	54	3	PS50105
Domain	SAM	CNKSR1 SAMHD1 SHANK3	2.78e-03	97	54	3	IPR001660
Domain	FYVE	ZFYVE26 WDFY3	3.17e-03	29	54	2	PF01363
Domain	FYVE	ZFYVE26 WDFY3	3.17e-03	29	54	2	SM00064
Domain	EGF_LAM_2	NTN3 STAB1	3.39e-03	30	54	2	PS50027
Domain	EGF_LAM_1	NTN3 STAB1	3.39e-03	30	54	2	PS01248
Domain	-	CNKSR1 SAMHD1 SHANK3	3.57e-03	106	54	3	1.10.150.50
Domain	PH	CNKSR1 PLEKHS1 ACAP3 AGAP2	4.31e-03	229	54	4	PF00169
Domain	Znf_FYVE-rel	ZFYVE26 WDFY3	4.34e-03	34	54	2	IPR017455
Domain	Laminin_EGF	NTN3 STAB1	4.59e-03	35	54	2	PF00053
Domain	EGF_Lam	NTN3 STAB1	4.59e-03	35	54	2	SM00180
Domain	SAM/pointed	CNKSR1 SAMHD1 SHANK3	4.71e-03	117	54	3	IPR013761
Domain	Znf_FYVE	ZFYVE26 WDFY3	5.40e-03	38	54	2	IPR000306
Domain	Laminin_EGF	NTN3 STAB1	5.40e-03	38	54	2	IPR002049
Domain	SOCS_box	ASB18 ASB10	5.40e-03	38	54	2	PF07525
Domain	SOCS_box	ASB18 ASB10	5.68e-03	39	54	2	SM00969
Domain	SOCS	ASB18 ASB10	5.68e-03	39	54	2	PS50225
Domain	SOCS_box	ASB18 ASB10	5.68e-03	39	54	2	IPR001496
Domain	ZF_FYVE	ZFYVE26 WDFY3	5.97e-03	40	54	2	PS50178
Domain	WD40	TRAF7 WDR4 WDFY3 ATG16L2	6.64e-03	259	54	4	PF00400
Domain	SAM_2	CNKSR1 SAMHD1	6.87e-03	43	54	2	PF07647
Domain	WD40	TRAF7 WDR4 WDFY3 ATG16L2	7.47e-03	268	54	4	SM00320
Domain	WD40_repeat	TRAF7 WDR4 WDFY3 ATG16L2	7.86e-03	272	54	4	IPR001680
Domain	PH	CNKSR1 PLEKHS1 ACAP3 AGAP2	8.48e-03	278	54	4	SM00233
Domain	WD_REPEATS_1	TRAF7 WDR4 WDFY3 ATG16L2	8.48e-03	278	54	4	PS00678
Domain	WD_REPEATS_2	TRAF7 WDR4 WDFY3 ATG16L2	8.58e-03	279	54	4	PS50082
Domain	WD_REPEATS_REGION	TRAF7 WDR4 WDFY3 ATG16L2	8.58e-03	279	54	4	PS50294
Domain	PH_DOMAIN	CNKSR1 PLEKHS1 ACAP3 AGAP2	8.58e-03	279	54	4	PS50003
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	MKRN4P KCTD7 TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM74	1.18e-07	299	40	9	MM15711
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	MKRN4P KCTD7 TRAF7 UBR1 ASB18 TRIM73 ASB10 TRIM50 TRIM74	3.78e-07	343	40	9	MM15712
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	MKRN4P KCTD7 TRAF7 UBR1 ASB18 RAPGEF3 TRIM73 ASB10 TRIM50 TRIM74	2.35e-05	719	40	10	MM14540
Pathway	PID_IL3_PATHWAY	JAK2 CNKSR1 PIM1	5.26e-05	26	40	3	M182
Pathway	WP_IL17_SIGNALING	JAK1 JAK2 IL17RC	9.92e-05	32	40	3	M39560
Pathway	BIOCARTA_IFNG_PATHWAY	JAK1 JAK2	1.17e-04	6	40	2	MM1590
Pathway	BIOCARTA_IFNG_PATHWAY	JAK1 JAK2	1.17e-04	6	40	2	M22085
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	KCTD7 TRAF7 UBR1 ASB18 ASB10 TRIM50	2.13e-04	308	40	6	M1070
Pathway	BIOCARTA_STAT3_PATHWAY	JAK1 JAK2	2.17e-04	8	40	2	MM1576
Pathway	BIOCARTA_STAT3_PATHWAY	JAK1 JAK2	2.17e-04	8	40	2	M22063
Pathway	REACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS	JAK1 JAK2	2.17e-04	8	40	2	M48010
Pathway	REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING	JAK1 JAK2 LGALS9	2.59e-04	44	40	3	M1012
Pathway	KEGG_MEDICUS_REFERENCE_CYTOKINE_JAK_STAT_SIGNALING_PATHWAY	JAK1 JAK2 PIM1	2.77e-04	45	40	3	M47408
Pathway	BIOCARTA_IL22BP_PATHWAY	JAK1 JAK2	2.79e-04	9	40	2	MM1419
Pathway	REACTOME_MAPK1_ERK2_ACTIVATION	JAK1 JAK2	2.79e-04	9	40	2	M26918
Pathway	BIOCARTA_IL22BP_PATHWAY	JAK1 JAK2	2.79e-04	9	40	2	M8066
Pathway	WP_IL26_SIGNALING	JAK1 JAK2 DCSTAMP	3.15e-04	47	40	3	M48074
Pathway	REACTOME_MAPK3_ERK1_ACTIVATION	JAK1 JAK2	3.48e-04	10	40	2	M26896
Pathway	WP_NETRINUNC5B_SIGNALING	NTN3 DCSTAMP AGAP2	4.25e-04	52	40	3	M39782
Pathway	REACTOME_INTERLEUKIN_6_SIGNALING	JAK1 JAK2	4.25e-04	11	40	2	M1014
Pathway	REACTOME_INTERLEUKIN_27_SIGNALING	JAK1 JAK2	4.25e-04	11	40	2	M27897
Pathway	REACTOME_INTERLEUKIN_35_SIGNALLING	JAK1 JAK2	5.09e-04	12	40	2	M27860
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	KCTD7 TRAF7 UBR1 ASB18 ASB10 TRIM50	6.61e-04	381	40	6	M1066
Pathway	PID_IL5_PATHWAY	JAK2 PIM1	6.99e-04	14	40	2	M135
Pathway	REACTOME_REGULATION_OF_IFNG_SIGNALING	JAK1 JAK2	6.99e-04	14	40	2	M942
Pathway	WP_IL5_SIGNALING_PATHWAY	JAK1 JAK2 PIM1	9.33e-04	68	40	3	MM15930
Pathway	REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS	JAK1 JAK2	1.04e-03	17	40	2	M27612
Pathway	WP_LEPTININSULIN_SIGNALING_OVERLAP	JAK2 DGKZ	1.04e-03	17	40	2	M39517
Pathway	WP_NCRNAS_INVOLVED_IN_STAT3_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA	JAK1 JAK2	1.04e-03	17	40	2	M39512
Pathway	WP_PROLACTIN_SIGNALING	JAK1 JAK2 AGAP2	1.29e-03	76	40	3	M39601
Pathway	WP_LEPTININSULIN_SIGNALING_OVERLAP	JAK2 DGKZ	1.44e-03	20	40	2	MM15867
Pathway	BIOCARTA_IL6_PATHWAY	JAK1 JAK2	1.59e-03	21	40	2	M5489
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY	JAK1 JAK2	1.59e-03	21	40	2	M47909
Pathway	BIOCARTA_IL6_PATHWAY	JAK1 JAK2	1.75e-03	22	40	2	MM1415
Pathway	WP_IMMUNE_RESPONSE_TO_TUBERCULOSIS	JAK1 JAK2	1.91e-03	23	40	2	M39748
Pathway	REACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION	JAK1 JAK2	1.91e-03	23	40	2	M26917
Pathway	REACTOME_INTERLEUKIN_6_FAMILY_SIGNALING	JAK1 JAK2	2.08e-03	24	40	2	M27604
Pathway	REACTOME_INACTIVATION_OF_CSF3_G_CSF_SIGNALING	JAK1 JAK2	2.26e-03	25	40	2	M41829
Pathway	REACTOME_INTERLEUKIN_20_FAMILY_SIGNALING	JAK1 JAK2	2.44e-03	26	40	2	M27750
Pathway	PID_IL27_PATHWAY	JAK1 JAK2	2.44e-03	26	40	2	M36
Pathway	REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING	JAK1 JAK2	2.63e-03	27	40	2	M921
Pathway	KEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY	JAK1 JAK2	2.63e-03	27	40	2	M47906
Pathway	WP_IL6_SIGNALING_PATHWAY	JAK1 JAK2 PPP2R3A	2.83e-03	100	40	3	MM15826
Pathway	WP_PDGFRBETA_PATHWAY	JAK1 JAK2	3.04e-03	29	40	2	M39616
Pathway	REACTOME_SIGNALING_BY_CSF3_G_CSF	JAK1 JAK2	3.25e-03	30	40	2	M41825
Pathway	KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY	JAK1 JAK2	3.47e-03	31	40	2	M47964
Pathway	WP_TYPE_II_INTERFERON_SIGNALING_IFNG	JAK1 JAK2	3.47e-03	31	40	2	MM15958
Pathway	REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING	JAK1 JAK2 PIM1	3.80e-03	111	40	3	M27609
Pubmed	Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.	TRIM73 TRIM50 TRIM74	4.17e-09	3	57	3	26196062
Pubmed	TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.	TRIM73 TRIM50 TRIM74	4.17e-09	3	57	3	22872646
Pubmed	Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.	TRIM73 TRIM50 TRIM74	4.16e-08	5	57	3	18398435
Pubmed	Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.	TRIM73 TRIM50 TRIM74	4.16e-08	5	57	3	20049703
Pubmed	TRIM50 regulates Beclin 1 proautophagic activity.	TRIM73 TRIM50 TRIM74	8.32e-08	6	57	3	29604308
Pubmed	TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.	TRIM73 TRIM50 TRIM74	8.32e-08	6	57	3	36178239
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	TRIM73 TRIM50 TRIM74	1.45e-07	7	57	3	26025256
Pubmed	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.	TRIM73 TRIM50 TRIM74	2.30e-06	16	57	3	22792322
Pubmed	Anti-myeloma effects of ruxolitinib combined with bortezomib and lenalidomide: A rationale for JAK/STAT pathway inhibition in myeloma patients.	JAK1 JAK2	2.64e-06	2	57	2	28645562
Pubmed	Ruxolitinib suppresses liver fibrosis progression and accelerates fibrosis reversal via selectively targeting Janus kinase 1/2.	JAK1 JAK2	2.64e-06	2	57	2	35382859
Pubmed	Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation.	JAK1 JAK2	2.64e-06	2	57	2	24169825
Pubmed	Oncogenic JAK1 and JAK2-activating mutations resistant to ATP-competitive inhibitors.	JAK1 JAK2	2.64e-06	2	57	2	21393331
Pubmed	Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT Effects.	JAK1 JAK2	2.64e-06	2	57	2	25977345
Pubmed	The Janus kinases inhibitor AZD1480 attenuates growth of small cell lung cancers in vitro and in vivo.	JAK1 JAK2	2.64e-06	2	57	2	24158701
Pubmed	Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells.	JAK1 JAK2	2.64e-06	2	57	2	22684105
Pubmed	SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.	JAK1 JAK2	2.64e-06	2	57	2	33827897
Pubmed	The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells.	JAK2 PIM1	2.64e-06	2	57	2	26472029
Pubmed	Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.	JAK1 JAK2	2.64e-06	2	57	2	1848670
Pubmed	Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies.	JAK1 JAK2	2.64e-06	2	57	2	29508247
Pubmed	Preclinical evaluation of JAK1/2 inhibition by ruxolitinib in a murine model of chronic graft-versus-host disease.	JAK1 JAK2	2.64e-06	2	57	2	33811972
Pubmed	Long-term efficacy and safety of momelotinib, a JAK1 and JAK2 inhibitor, for the treatment of myelofibrosis.	JAK1 JAK2	2.64e-06	2	57	2	29263442
Pubmed	Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice.	JAK1 JAK2	2.64e-06	2	57	2	27222478
Pubmed	Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations.	JAK1 JAK2	2.64e-06	2	57	2	27903500
Pubmed	Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24.	JAK1 JAK2	2.64e-06	2	57	2	1581631
Pubmed	Combined inhibition of Janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.	JAK1 JAK2	2.64e-06	2	57	2	19887489
Pubmed	CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.	JAK1 JAK2	7.91e-06	3	57	2	26175413
Pubmed	Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia.	JAK1 JAK2	7.91e-06	3	57	2	21537335
Pubmed	Janus kinases 1 and 2 regulate chemokine-mediated integrin activation and naïve T-cell homing.	JAK1 JAK2	7.91e-06	3	57	2	23526587
Pubmed	Progesterone activates Janus Kinase 1/2 and activators of transcription 1 (JAK1-2/STAT1) pathway in human spermatozoa.	JAK1 JAK2	7.91e-06	3	57	2	22748021
Pubmed	Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.	JAK1 JAK2	7.91e-06	3	57	2	17550976
Pubmed	Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase.	JAK1 JAK2	7.91e-06	3	57	2	9548458
Pubmed	Jak3 maps to chromosome 8.	JAK1 JAK2	7.91e-06	3	57	2	8662243
Pubmed	Structural organization and chromosomal mapping of JAK3 locus.	JAK1 JAK2	7.91e-06	3	57	2	8934548
Pubmed	Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways.	JAK1 JAK2	7.91e-06	3	57	2	26901336
Pubmed	PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.	PIM1 SAMHD1	7.91e-06	3	57	2	31015445
Pubmed	Induction of Jak/STAT signaling by activation of the type 1 TNF receptor.	JAK1 JAK2	7.91e-06	3	57	2	9510175
Pubmed	Involvement of JAK1, JAK2, and JAK3 in Stimulation of Functional Activity of Mesenchymal Progenitor Cells by Fibroblast Growth Factor.	JAK1 JAK2	7.91e-06	3	57	2	27905037
Pubmed	Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling.	JAK1 JAK2	7.91e-06	3	57	2	21965659
Pubmed	Signal transduction by the atopy-associated human thymic stromal lymphopoietin (TSLP) receptor depends on Janus kinase function.	JAK1 JAK2	7.91e-06	3	57	2	20128689
Pubmed	Implication of JAK1, JAK2, and JAK3 in the Realization of Proliferation and Differentiation Potential of Mesenchymal Progenitor Cells In Vitro.	JAK1 JAK2	7.91e-06	3	57	2	27383175
Pubmed	Age-associated inflammation inhibits epidermal stem cell function.	JAK1 JAK2	7.91e-06	3	57	2	22972935
Pubmed	Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children.	JAK1 JAK2	7.91e-06	3	57	2	27554814
Pubmed	JAK mutations in high-risk childhood acute lymphoblastic leukemia.	JAK1 JAK2	7.91e-06	3	57	2	19470474
Pubmed	LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.	JAK1 JAK2	7.91e-06	3	57	2	21151131
Pubmed	A preliminary study of new single polymorphisms in the T helper type 17 pathway for psoriasis in the Korean population.	JAK1 JAK2	7.91e-06	3	57	2	27774581
Pubmed	Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.	JAK1 JAK2	7.91e-06	3	57	2	8272873
Pubmed	The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes.	JAK1 JAK2	7.91e-06	3	57	2	29162613
Pubmed	Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.	JAK1 JAK2	7.91e-06	3	57	2	8378315
Pubmed	INCB16562, a JAK1/2 selective inhibitor, is efficacious against multiple myeloma cells and reverses the protective effects of cytokine and stromal cell support.	JAK1 JAK2	7.91e-06	3	57	2	20072651
Pubmed	Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130.	JAK1 JAK2	7.91e-06	3	57	2	10586060
Pubmed	YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling.	JAK1 JAK2	7.91e-06	3	57	2	12551917
Pubmed	The Janus kinase family of protein tyrosine kinases and their role in signaling.	JAK1 JAK2	7.91e-06	3	57	2	10526570
Pubmed	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.	NPY4R2 NPY4R	7.91e-06	3	57	2	8643460
Pubmed	Amorfrutin A inhibits TNF-α induced JAK/STAT signaling, cell survival and proliferation of human cancer cells.	JAK1 JAK2	7.91e-06	3	57	2	28879797
Pubmed	Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.	JAK1 JAK2	7.91e-06	3	57	2	15923602
Pubmed	Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes.	JAK1 JAK2	7.91e-06	3	57	2	7539296
Pubmed	Piperlongumine inhibits gastric cancer cells via suppression of the JAK1,2/STAT3 signaling pathway.	JAK1 JAK2	7.91e-06	3	57	2	27053336
Pubmed	Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.	JAK1 JAK2	7.91e-06	3	57	2	32001089
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	NHLRC1 JAK1 TRAF7 NOP9 CTC1 NTN3 DGKZ ZFYVE26 STAB1	7.91e-06	832	57	9	36724073
Pubmed	The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.	JAK2 PIM1	1.58e-05	4	57	2	18216297
Pubmed	Dipyrithione inhibits IFN-gamma-induced JAK/STAT1 signaling pathway activation and IP-10/CXCL10 expression in RAW264.7 cells.	JAK1 JAK2	1.58e-05	4	57	2	20372968
Pubmed	Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia.	JAK1 JAK2	1.58e-05	4	57	2	20139093
Pubmed	Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.	JAK1 JAK2	1.58e-05	4	57	2	15988755
Pubmed	CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.	JAK1 JAK2	1.58e-05	4	57	2	28278176
Pubmed	Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases.	JAK1 JAK2	1.58e-05	4	57	2	8995399
Pubmed	Loss of JAK1 Drives Innate Immune Deficiency.	JAK1 JAK2	1.58e-05	4	57	2	30671064
Pubmed	Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases.	JAK1 JAK2	1.58e-05	4	57	2	9452495
Pubmed	Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance.	JAK1 JAK2	1.58e-05	4	57	2	23406773
Pubmed	Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins.	JAK1 JAK2	1.58e-05	4	57	2	8657151
Pubmed	Box 2 region of the oncostatin M receptor determines specificity for recruitment of Janus kinases and STAT5 activation.	JAK1 JAK2	1.58e-05	4	57	2	18430728
Pubmed	Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway.	JAK1 JAK2	1.58e-05	4	57	2	23818941
Pubmed	JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation.	JAK1 JAK2	1.58e-05	4	57	2	9516124
Pubmed	Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.	JAK1 JAK2	1.58e-05	4	57	2	9553136
Pubmed	Involvement of Janus kinases in the insulin signaling pathway.	JAK1 JAK2	1.58e-05	4	57	2	8536716
Pubmed	IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1, 2/Stat6 signal transduction pathway: Implication for atopic dermatitis.	JAK1 JAK2	1.58e-05	4	57	2	22226123
Pubmed	Regulation of the Jak/STAT signalling pathway.	JAK1 JAK2	1.58e-05	4	57	2	8593242
Pubmed	Structure of the pseudokinase-kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition.	JAK1 JAK2	1.58e-05	4	57	2	24843152
Pubmed	Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro.	JAK1 JAK2	1.58e-05	4	57	2	23941832
Pubmed	Three distinct signalling responses by murine fibroblasts to genotoxic stress.	JAK1 JAK2	1.58e-05	4	57	2	8918879
Pubmed	Interferon-γ stimulates human follicular dendritic cell-like cells to produce prostaglandins via the JAK-STAT pathway.	JAK1 JAK2	1.58e-05	4	57	2	25818476
Pubmed	Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2.	JAK2 PIM1	1.58e-05	4	57	2	18775810
Pubmed	Involvement of JAK/STAT (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway.	JAK1 JAK2	1.58e-05	4	57	2	10809230
Pubmed	Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells.	JAK1 JAK2	1.58e-05	4	57	2	11163768
Pubmed	JAK pathway induction of c-Myc critical to IL-5 stimulation of cell proliferation and inhibition of apoptosis.	JAK1 JAK2	1.58e-05	4	57	2	19180571
Pubmed	Selective regulation of interleukin-10 production via Janus kinase pathway in murine conventional dendritic cells.	JAK1 JAK2	1.58e-05	4	57	2	19361784
Pubmed	Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.	NPY4R2 NPY4R	1.58e-05	4	57	2	7592911
Pubmed	CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling.	JAK1 JAK2	1.58e-05	4	57	2	11201744
Pubmed	Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.	JAK1 JAK2	1.58e-05	4	57	2	28965767
Pubmed	Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.	JAK1 JAK2	1.58e-05	4	57	2	8041779
Pubmed	The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver.	JAK1 JAK2	1.58e-05	4	57	2	10502458
Pubmed	STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction.	JAK1 JAK2	1.58e-05	4	57	2	9133424
Pubmed	The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities.	JAK1 JAK2	1.58e-05	4	57	2	15659653
Pubmed	The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.	JAK1 JAK2	2.63e-05	5	57	2	10531356
Pubmed	Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases.	JAK1 JAK2	2.63e-05	5	57	2	7544789
Pubmed	Controlling nuclear JAKs and STATs for specific gene activation by IFNγ.	JAK1 JAK2	2.63e-05	5	57	2	21689637
Pubmed	Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.	JAK1 JAK2	2.63e-05	5	57	2	12456798
Pubmed	Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.	NPY4R2 NPY4R	2.63e-05	5	57	2	7493937
Pubmed	The Janus kinase 1 is critical for pancreatic cancer initiation and progression.	JAK1 JAK2	2.63e-05	5	57	2	38733583
Pubmed	The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2.	JAK1 JAK2	2.63e-05	5	57	2	12223098
Pubmed	Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.	JAK1 JAK2	2.63e-05	5	57	2	24398427
Cytoband	7q11.23	TRIM73 TRIM50 GSAP TRIM74	6.79e-06	97	57	4	7q11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	KCTD7 TRIM73 TRIM50 GSAP TRIM74	2.25e-05	271	57	5	chr7q11
Cytoband	1p36.11	CNKSR1 PIGV	3.27e-03	68	57	2	1p36.11
GeneFamily	Ring finger proteins	MKRN4P TRAF7 TRIM73 TRIM50 TRIM44 TRIM74	3.37e-05	275	41	6	58
GeneFamily	ArfGAPs	ARFGAP2 ACAP3 AGAP2	5.63e-05	33	41	3	395
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM73 TRIM50 TRIM44 TRIM74	6.24e-05	95	41	4	59
GeneFamily	Ankyrin repeat domain containing	ASB18 ASB10 SHANK3 ACAP3 AGAP2	2.08e-04	242	41	5	403
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	ACAP3 AGAP2	6.68e-04	17	41	2	1291
GeneFamily	Sterile alpha motif domain containing	CNKSR1 SAMHD1 SHANK3	1.04e-03	88	41	3	760
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CNKSR1 PLEKHS1 ACAP3 AGAP2	1.19e-03	206	41	4	682
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE26 WDFY3	2.24e-03	31	41	2	81
GeneFamily	WD repeat domain containing	TRAF7 WDR4 WDFY3 ATG16L2	2.86e-03	262	41	4	362
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	JAK1 JAK2	5.74e-03	50	41	2	1293
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP	KCTD7 ARFGAP2 CTC1 DGKZ SAMHD1 TRIM44	3.39e-06	199	54	6	M4521
Drug	tetraethylenepentamine pentahydrochloride; Down 200; 100uM; MCF7; HG-U133A	TUT4 CTC1 GLG1 SAMHD1 PIGV AGAP2	5.85e-06	198	52	6	406_DN
Drug	Clorsulon [60200-06-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A	JAK2 WDR4 CTC1 GLG1 SAMHD1 WDFY3	6.02e-06	199	52	6	7025_DN
Disease	Manic mood	SHANK3 STAB1	1.97e-05	4	54	2	C0564408
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK1 JAK2	6.86e-05	7	54	2	DOID:14566 (implicated_via_orthology)
Disease	Polycythemia Vera	JAK1 JAK2	9.14e-05	8	54	2	C0032463
Disease	hematologic cancer (implicated_via_orthology)	JAK1 JAK2	2.53e-04	13	54	2	DOID:2531 (implicated_via_orthology)
Disease	non-alcoholic fatty liver disease (implicated_via_orthology)	JAK2 UBR1	1.99e-03	36	54	2	DOID:0080208 (implicated_via_orthology)
Disease	Microcalcification	JAK2 CTC1	2.70e-03	42	54	2	C0521174
Disease	Calcinosis	JAK2 CTC1	2.70e-03	42	54	2	C0006663

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILCCLLGHAIHGLLV	SLC1A5	306	Q15758
HINPAVTVACLVGCH	AQP2	66	P41181
LCLGHATRCIHLETQ	ERVK11-1	31	P61568
CNDVVCGDHIIISGH	ATG16L2	466	Q8NAA4
CKVTCHELCHLLGLG	AMZ1	256	Q400G9
VTCRNHHVAAALGLC	CTC1	1086	Q2NKJ3
CAAGHTACVHVLLVA	ASB10	156	Q8WXI3
INLGVLLCIECSGIH	ACAP3	431	Q96P50
CIECSGIHRNLGTHL	AGAP2	966	Q99490
CIDCSGVHRSLGVHL	ARFGAP2	46	Q8N6H7
IFICGEAVQGNCVHH	ANGPTL5	16	Q86XS5
LHGDLCDMCGLQVLH	MKRN4P	266	Q13434
LIVHNIQNGCHGPIC	JAK1	431	P23458
HKHLVLNYGVCVCGD	JAK2	606	O60674
VACHRCGVHVLQSAL	NOP9	136	Q86U38
GLTVDHQCIGVCDKH	KCTD7	256	Q96MP8
PICHGNLIFLVCHLL	NPY4R	296	P50391
LHEACLGGHTACVRL	ASB18	156	Q6ZVZ8
LCEAHCLKVAVDGQH	LGALS9	311	O00182
VVGCLGIHIKNCRHF	C2CD6	106	Q53TS8
AVIVGCLCHDLDHRG	PDE11A	696	Q9HCR9
QHLGVCCLVALISVG	DCSTAMP	31	Q9H295
GIDCIVVHHSVCADL	PPP2R3A	41	Q06190
LDTQGHLICDCRHGT	NTN3	266	O00634
ILSCRGEIEHHCSGL	GLG1	441	Q92896
GVQCLPLHNLLHCID	GSAP	706	A4D1B5
ACVLHDVIYVIGGHC	KLHL23	411	Q8NBE8
QLLGALTGCVQHICA	C1orf112	61	Q9NSG2
CALLQGHCVVTATHL	IQCF2	141	Q8IXL9
CLHQAAALGQRTICH	DGKZ	861	Q13574
CLVCLTAALAHGCLH	IZUMO4	6	Q1ZYL8
CGHVVCLACVAALAH	NHLRC1	46	Q6VVB1
CDLCLRVAVHLAVHG	IL17RC	151	Q8NAC3
VLEAVRHCHNCGVLH	PIM1	151	P11309
LICVLCPVIGAHQGH	TRIM44	196	Q96DX7
VLCVQIAGLCHDLGH	SAMHD1	196	Q9Y3Z3
VACVCEALLQAGHAG	SIX5	91	Q8N196
LRICSHVAGICHNIL	CNKSR1	171	Q969H4
AVALHDLGCLVLHCP	PIGV	131	Q9NUD9
CIFCHGDHLLAVNDL	PLEKHS1	356	Q5SXH7
LICGLCGLLGSHQHH	TRIM74	106	Q86UV6
CQVLLDEGALCHVKH	RAPGEF3	156	O95398
ISCLAHCLINLHVGS	WDFY3	2141	Q8IZQ1
LCCELLLHDHAQLGI	SHANK3	231	Q9BYB0
RDAIVHTLQACHGCV	PRR19	171	A6NJB7
EGHDGIVLALCIQGC	TRAF7	436	Q6Q0C0
NGEEVGACIFHALHC	UBR1	1646	Q8IWV7
HALHCGAGVCIFLKI	UBR1	1656	Q8IWV7
EHLGDLLSHCQECGL	TANGO6	576	Q9C0B7
PICHGNLIFLVCHLL	NPY4R2	296	P0DQD5
QEINSCLIHHGGCHI	STAB1	1496	Q9NY15
QGHLDLCEQHCAILL	TTC21A	936	Q8NDW8
GTLQRLASHHIGECC	ZNF888	71	P0CJ79
LICGLCGLLGSHQHH	TRIM73	106	Q86UV7
GRQLHCCHLASLQEL	WDR4	221	P57081
LCQVLHVAGGQLHAA	VSIG10L2	121	P0DP72
CKLCLIHIENIQGAH	TUT4	306	Q5TAX3
LICGLCGLLGSHQHH	TRIM50	106	Q86XT4
GHQLIEHCCRLSKGL	ZFYVE26	1951	Q68DK2