Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activator activity

CCND3 CCND1 CCND2

2.05e-0516683GO:0061575
GeneOntologyMolecularFunctionzinc ion binding

PAPPA2 TET2 RAG1 SETDB2 KDM5B DDAH1 ADAMTS9 MARCHF6 DTX2 TRIM6 RNF217 RNF24

4.20e-058916812GO:0008270
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

6.83e-054682GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

1.70e-046682GO:0048763
GeneOntologyMolecularFunctionstructural molecule activity

COL2A1 CRELD1 TUBB4A TUBB4B FBN1 EFEMP1 SHANK2 COL6A6 TUBB MACF1 BGLAP

1.96e-048916811GO:0005198
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 TAF1L RNF115

1.99e-04473688GO:0004842
GeneOntologyMolecularFunctioncalcium ion binding

CRELD1 TUBB4A FBN1 EFEMP1 LRP2 MACF1 RYR2 RYR3 BGLAP RAB11FIP3

2.11e-047496810GO:0005509
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 RNF115

2.69e-04372687GO:0061630
GeneOntologyMolecularFunctionhydroxyapatite binding

MUC19 BGLAP

3.16e-048682GO:0046848
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 TAF1L RNF115

3.39e-04512688GO:0019787
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 RNF115

4.04e-04398687GO:0061659
GeneOntologyMolecularFunctionaminoacyltransferase activity

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 TAF1L RNF115

4.37e-04532688GO:0016755
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL2A1 CRELD1 FBN1 EFEMP1 COL6A6

4.52e-04188685GO:0005201
GeneOntologyMolecularFunctiontransition metal ion binding

PAPPA2 TET2 RAG1 SETDB2 KDM5B DDAH1 ADAMTS9 MARCHF6 DTX2 TRIM6 RNF217 RNF24

6.16e-0411896812GO:0046914
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase regulator activity

CCND3 CCND1 CCND2

7.00e-0451683GO:0016538
GeneOntologyMolecularFunctionMHC protein binding

COL2A1 TUBB4B TUBB

1.02e-0358683GO:0042287
GeneOntologyMolecularFunctionhistone modifying activity

RSBN1 SETDB2 KDM5B SMYD1 TAF1L

1.10e-03229685GO:0140993
GeneOntologyMolecularFunctionmicrotubule minus-end binding

MACF1 CAMSAP2

1.17e-0315682GO:0051011
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

TET2 RSBN1 KDM5B

1.42e-0365683GO:0016706
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

MST1R EFEMP1 CRIM1

1.42e-0365683GO:0004714
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR2 RYR3

1.69e-0318682GO:0015278
GeneOntologyMolecularFunctionp53 binding

TAF1L TP53BP1 TP53BP2

2.31e-0377683GO:0002039
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

CCND3 CCND1 CCND2

2.39e-0378683GO:0043539
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

MST1R EFEMP1 CRIM1

3.06e-0385683GO:0019199
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

CCND3 SPDYE3 CCND1 CCND2

1.22e-0625674GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

CCND3 SPDYE3 CCND1 CCND2

1.96e-0628674GO:1904031
GeneOntologyBiologicalProcessheart development

COL2A1 CRELD1 SIN3B SETDB2 FBN1 ADAMTS9 SMYD1 LRP2 RYR2 TP53BP2 CCND2

2.98e-057576711GO:0007507
GeneOntologyCellularComponentintercellular bridge

TUBB4A TUBB4B SETX TUBB RAB11FIP3

1.48e-0594695GO:0045171
GeneOntologyCellularComponenttubulin complex

TUBB4B TUBB

3.21e-053692GO:0045298
DomainCyclin_D

CCND3 CCND1 CCND2

4.62e-083683IPR015451
DomainZnf_C3HC4_RING-type

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF24 RNF115

3.00e-06172687IPR018957
DomainBeta-tubulin_BS

TUBB4A TUBB4B TUBB

5.44e-0610683IPR013838
DomainBeta_tubulin

TUBB4A TUBB4B TUBB

5.44e-0610683IPR002453
DomainTUBULIN_B_AUTOREG

TUBB4A TUBB4B TUBB

7.46e-0611683PS00228
Domainzf-C3HC4

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF24 RNF115

1.64e-05223687PF00097
DomainCyclin_C

CCND3 CCND1 CCND2

3.03e-0517683PF02984
DomainCyclin_C-dom

CCND3 CCND1 CCND2

3.03e-0517683IPR004367
DomainCyclin_C

CCND3 CCND1 CCND2

3.03e-0517683SM01332
DomainRyanrecept_TM4-6

RYR2 RYR3

3.91e-053682IPR009460
DomainRyR

RYR2 RYR3

3.91e-053682PF02026
DomainRyanodine_rcpt

RYR2 RYR3

3.91e-053682IPR003032
DomainRR_TM4-6

RYR2 RYR3

3.91e-053682PF06459
DomainRyan_recept

RYR2 RYR3

3.91e-053682IPR013333
Domain-

TUBB4A TUBB4B TUBB

5.03e-05206833.30.1330.20
Domain-

TUBB4A TUBB4B TUBB

5.86e-05216831.10.287.600
DomainTubulin_C

TUBB4A TUBB4B TUBB

6.76e-0522683SM00865
DomainTubulin_C

TUBB4A TUBB4B TUBB

6.76e-0522683PF03953
DomainTubulin/FtsZ_2-layer-sand-dom

TUBB4A TUBB4B TUBB

6.76e-0522683IPR018316
Domain-

TUBB4A TUBB4B TUBB

6.76e-05226833.40.50.1440
DomainTubulin_C

TUBB4A TUBB4B TUBB

7.76e-0523683IPR023123
DomainTUBULIN

TUBB4A TUBB4B TUBB

7.76e-0523683PS00227
DomainTubulin

TUBB4A TUBB4B TUBB

7.76e-0523683IPR000217
DomainTub_FtsZ_C

TUBB4A TUBB4B TUBB

7.76e-0523683IPR008280
DomainTubulin

TUBB4A TUBB4B TUBB

7.76e-0523683SM00864
DomainTubulin_CS

TUBB4A TUBB4B TUBB

7.76e-0523683IPR017975
DomainTubulin_FtsZ_GTPase

TUBB4A TUBB4B TUBB

8.84e-0524683IPR003008
DomainTubulin

TUBB4A TUBB4B TUBB

8.84e-0524683PF00091
DomainZF_RING_1

RAG1 RNF181 DTX2 TRIM6 RNF217 RNF24 RNF115

8.92e-05291687PS00518
DomainZF_RING_2

RAG1 RNF181 DTX2 TRIM6 RNF217 RNF24 RNF115

1.03e-04298687PS50089
DomaincEGF

FBN1 EFEMP1 LRP2

1.13e-0426683IPR026823
DomaincEGF

FBN1 EFEMP1 LRP2

1.13e-0426683PF12662
DomainCYCLINS

CCND3 CCND1 CCND2

1.42e-0428683PS00292
DomainZnf_RING

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF24 RNF115

1.80e-04326687IPR001841
DomainRIH_assoc

RYR2 RYR3

1.94e-046682PF08454
DomainRIH_assoc-dom

RYR2 RYR3

1.94e-046682IPR013662
DomainRIH_dom

RYR2 RYR3

1.94e-046682IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

1.94e-046682IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

1.94e-046682IPR015925
Domain-

RYR2 RYR3

1.94e-0466821.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

1.94e-046682PF01365
DomainIns145_P3_rec

RYR2 RYR3

1.94e-046682PF08709
Domain-

RAG1 KDM5B RNF181 MARCHF6 DTX2 TRIM6 RNF24 RNF115

2.19e-044496883.30.40.10
DomainCyclin_N

CCND3 CCND1 CCND2

2.33e-0433683IPR006671
DomainCyclin_N

CCND3 CCND1 CCND2

2.33e-0433683PF00134
DomainZnf_RING/FYVE/PHD

RAG1 KDM5B RNF181 MARCHF6 DTX2 TRIM6 RNF24 RNF115

2.54e-04459688IPR013083
DomainGrowth_fac_rcpt_

CRELD1 FBN1 EFEMP1 CRIM1 LRP2

2.60e-04156685IPR009030
DomainEGF_CA

CRELD1 FBN1 EFEMP1 LRP2

2.73e-0486684PF07645
DomainVWC

COL2A1 CRIM1 MUC19

3.55e-0438683SM00214
DomainVWFC_2

COL2A1 CRIM1 MUC19

3.55e-0438683PS50184
DomainCYCLIN

CCND3 CCND1 CCND2

3.55e-0438683SM00385
Domain-

CCND3 CCND1 CCND2

4.14e-04406831.10.472.10
DomainEGF_Ca-bd_CS

CRELD1 FBN1 EFEMP1 LRP2

4.32e-0497684IPR018097
DomainEGF_CA

CRELD1 FBN1 EFEMP1 LRP2

4.66e-0499684PS01187
DomainVWF_dom

COL2A1 CRIM1 MUC19

4.79e-0442683IPR001007
DomainASX_HYDROXYL

CRELD1 FBN1 EFEMP1 LRP2

4.85e-04100684PS00010
DomainCyclin-like

CCND3 CCND1 CCND2

5.13e-0443683IPR013763
DomainMIR

RYR2 RYR3

5.77e-0410682PS50919
DomainMIR

RYR2 RYR3

5.77e-0410682PF02815
DomainMIR

RYR2 RYR3

5.77e-0410682SM00472
DomainMIR_motif

RYR2 RYR3

5.77e-0410682IPR016093
DomainEGF-type_Asp/Asn_hydroxyl_site

CRELD1 FBN1 EFEMP1 LRP2

6.04e-04106684IPR000152
DomainRING

RAG1 RNF181 DTX2 TRIM6 RNF24 RNF115

8.45e-04305686SM00184
Domainzf-RING_2

RNF181 RNF24 RNF115

8.98e-0452683PF13639
DomainEGF_CA

CRELD1 FBN1 EFEMP1 LRP2

1.02e-03122684SM00179
DomainEGF-like_Ca-bd_dom

CRELD1 FBN1 EFEMP1 LRP2

1.09e-03124684IPR001881
DomainTIL_dom

MUC19 LRP2

1.16e-0314682IPR002919
Domain-

KDM5B ARID4B

1.33e-03156821.10.150.60
DomainBRIGHT

KDM5B ARID4B

1.33e-0315682SM00501
DomainARID_dom

KDM5B ARID4B

1.33e-0315682IPR001606
DomainARID

KDM5B ARID4B

1.33e-0315682PS51011
DomainARID

KDM5B ARID4B

1.33e-0315682PF01388
DomainEGF_3

CRELD1 FBN1 EFEMP1 LRP2 GP2

1.65e-03235685PS50026
DomainZnf_RING-CH

MARCHF6 RNF24

1.71e-0317682IPR011016
DomainRINGv

MARCHF6 RNF24

1.71e-0317682SM00744
DomainEGF-like_dom

CRELD1 FBN1 EFEMP1 LRP2 GP2

2.13e-03249685IPR000742
DomainVWC_out

CRIM1 MUC19

2.15e-0319682SM00215
DomainEF-hand_1

MACF1 RYR2 RYR3 RAB11FIP3

2.29e-03152684PF00036
DomainEGF_1

CRELD1 FBN1 EFEMP1 LRP2 GP2

2.36e-03255685PS00022
DomainEGF-like_CS

CRELD1 FBN1 EFEMP1 LRP2 GP2

2.61e-03261685IPR013032
DomainEGF_2

CRELD1 FBN1 EFEMP1 LRP2 GP2

2.79e-03265685PS01186
DomainADAM_spacer1

ADAMTS9 ADAMTSL2

3.15e-0323682IPR010294
DomainADAM_spacer1

ADAMTS9 ADAMTSL2

3.15e-0323682PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS9 ADAMTSL2

3.42e-0324682IPR013273
PathwayREACTOME_DRUG_MEDIATED_INHIBITION_OF_CDK4_CDK6_ACTIVITY

CCND3 CCND1 CCND2

5.59e-075553M45016
PathwayREACTOME_DRUG_MEDIATED_INHIBITION_OF_CDK4_CDK6_ACTIVITY

CCND3 CCND1 CCND2

5.59e-075553MM15696
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

CCND3 CCND1 CCND2

1.95e-067553MM15524
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_CDK4_TO_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

3.10e-068553M47419
PathwayKEGG_MEDICUS_PATHOGEN_EBV_EBNA3C_TO_CELL_CYCLE_G1_S_N00483

CCND3 CCND1 CCND2

4.64e-069553M49010
PathwayKEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

6.61e-0610553M47418
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

9.07e-0611553M47426
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MDM2_TO_P21_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

1.21e-0512553M47417
PathwayKEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066

CCND3 CCND1 CCND2

1.56e-0513553M47416
PathwayKEGG_MEDICUS_REFERENCE_P15_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

1.56e-0513553M49035
PathwayKEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S

CCND3 CCND1 CCND2

2.47e-0515553M47524
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

CCND3 CCND1 CCND2

3.68e-0517553M27788
PathwayREACTOME_ABERRANT_REGULATION_OF_MITOTIC_G1_S_TRANSITION_IN_CANCER_DUE_TO_RB1_DEFECTS

CCND3 CCND1 CCND2

3.68e-0517553M38998
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY

TUBB4A TUBB4B TUBB

3.68e-0517553M47768
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

4.40e-0518553M47753
PathwayKEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

5.21e-0519553M47818
PathwayKEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

5.21e-0519553M47813
PathwayKEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT

TUBB4A TUBB4B TUBB

6.11e-0520553M47890
PathwayKEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS

TUBB4A TUBB4B TUBB

6.11e-0520553M47911
PathwayKEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY

TUBB4A TUBB4B TUBB

7.11e-0521553M47767
PathwayKEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH

TUBB4A TUBB4B TUBB

8.21e-0522553M47903
PathwayBIOCARTA_CELLCYCLE_PATHWAY

CCND3 CCND1 CCND2

9.42e-0523553M17770
PathwayKEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION

TUBB4A TUBB4B TUBB

9.42e-0523553M47910
PathwayKEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION

TUBB4A TUBB4B TUBB

9.42e-0523553M47900
PathwayBIOCARTA_CELLCYCLE_PATHWAY

CCND3 CCND1 CCND2

1.07e-0424553MM1376
PathwayKEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

1.07e-0424553M47671
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

1.07e-0424553M47700
PathwayPID_RB_1PATHWAY

CCND3 CCND1 BGLAP CCND2

1.18e-0465554M279
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

TUBB4A TUBB4B TUBB

1.22e-0425553M47775
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

1.22e-0425553M47710
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

1.37e-0426553M47672
PathwayWP_DNA_DAMAGE_RESPONSE

CCND3 ATRIP CCND1 CCND2

1.49e-0469554M39339
PathwayWP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY

TUBB4A TUBB4B UBA1 TUBB

1.66e-0471554M39690
PathwayKEGG_MEDICUS_REFERENCE_MICROTUBULE_NUCLEATION

TUBB4A TUBB4B TUBB

1.72e-0428553M47898
PathwayKEGG_MEDICUS_REFERENCE_BRANCHING_MICROTUBULE_NUCLEATION

TUBB4A TUBB4B TUBB

2.82e-0433553M47901
PathwayWP_MIR193A_AND_MVP_IN_COLON_CANCER_METASTASIS

CCND1 CCND2

3.10e-047552MM15853
PathwayKEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT

TUBB4A TUBB4B TUBB

3.37e-0435553M47774
PathwayREACTOME_DISEASES_OF_MITOTIC_CELL_CYCLE

CCND3 CCND1 CCND2

4.30e-0438553M39005
PathwayWP_MIRNA_REGULATION_OF_DNA_DAMAGE_RESPONSE

CCND3 ATRIP CCND1 CCND2

5.71e-0498554M39524
PathwayWP_HEDGEHOG_SIGNALING_WP4249

LRP2 CCND1 CCND2

6.21e-0443553M39706
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

6.21e-0443553M47669
PathwayKEGG_MEDICUS_REFERENCE_RAB7_REGULATED_MICROTUBULE_MINUS_END_DIRECTED_TRANSPORT

TUBB4A TUBB4B TUBB

6.21e-0443553M47773
PathwayREACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1

CCND3 CCND1 CCND2

6.65e-0444553MM15377
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

TUBB4A TUBB4B TUBB

7.10e-0445553M47670
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR2 RYR3

8.04e-0411552M47958
PathwayREACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1

CCND3 CCND1 CCND2

8.07e-0447553M29724
PathwayKEGG_FOCAL_ADHESION

COL2A1 CCND3 COL6A6 CCND1 CCND2

1.05e-03199555M7253
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR2 RYR3

1.13e-0313552M39589
PathwayWP_PATHOGENIC_ESCHERICHIA_COLI_INFECTION

TUBB4A TUBB4B TUBB

1.28e-0355553M39613
PathwayKEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION

TUBB4A TUBB4B TUBB

1.35e-0356553M2333
PathwayWP_G1_TO_S_CELL_CYCLE_CONTROL

CCND3 CCND1 CCND2

1.72e-0361553MM15912
PathwayWP_WNT_SIGNALING

CCND3 CCND1 CCND2

1.72e-0361553MM15893
PathwayREACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE

TUBB4A TUBB4B

1.96e-0317552MM14731
PathwayWP_G1_TO_S_CELL_CYCLE_CONTROL

CCND3 CCND1 CCND2

1.98e-0364553M39627
PathwayWP_P53_SIGNALING

CCND3 CCND1 CCND2

2.07e-0365553MM15852
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL2A1 FBN1 COL6A6 ADAMTS9

2.15e-03140554M587
PathwayREACTOME_PKR_MEDIATED_SIGNALING

FANCB TUBB4A TUBB4B

2.16e-0366553MM17074
PathwayREACTOME_CELL_CYCLE

CCND3 TUBB4A TUBB4B ATRIP TUBB CCND1 TP53BP1 CCND2

2.20e-03603558MM14635
PathwayKEGG_P53_SIGNALING_PATHWAY

CCND3 CCND1 CCND2

2.35e-0368553M6370
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR2 RYR3

2.45e-0319552M47760
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

TUBB4A TUBB4B TUBB

2.66e-0371553MM15495
PathwayREACTOME_NCAM1_INTERACTIONS

COL2A1 COL6A6

2.71e-0320552MM15061
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

TUBB4A TUBB4B TUBB

2.77e-0372553M27749
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

CCND3 SIN3B CCND1 CCND2

2.96e-03153554MM15522
PathwayREACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE

TUBB4A TUBB4B

2.99e-0321552M27067
PathwayREACTOME_PKR_MEDIATED_SIGNALING

FANCB TUBB4A TUBB4B

3.23e-0376553M48037
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL2A1 FBN1 COL6A6

3.23e-0376553MM14867
PathwayREACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY

TUBB4A TUBB4B

3.59e-0323552M19135
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

TUBB4A TUBB4B TUBB

3.87e-0381553M748
Pubmed

Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice.

CCND3 CCND1 CCND2

7.47e-09369315576649
Pubmed

Involvement of the D-type cyclins in germ cell proliferation and differentiation in the mouse.

CCND3 CCND1 CCND2

7.47e-09369311090462
Pubmed

Segment- and cell-specific expression of D-type cyclins in the postnatal mouse epididymis.

CCND3 CCND1 CCND2

7.47e-09369322289519
Pubmed

Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.

CCND3 CCND1 CCND2

7.47e-09369315755896
Pubmed

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

CCND3 CCND1 CCND2

7.47e-09369320090754
Pubmed

Crucial roles of D-type cyclins in the early stage of adipocyte differentiation.

CCND3 CCND1 CCND2

7.47e-09369318374658
Pubmed

Differential expression of D-type cyclins in HaCaT keratinocytes and in psoriasis.

CCND3 CCND1 CCND2

7.47e-09369317882269
Pubmed

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.

CCND3 CCND1 CCND2

7.47e-09369322929040
Pubmed

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth.

CCND3 CCND1 CCND2

7.47e-09369315831479
Pubmed

Elimination of cyclin D1 in vertebrate cells leads to an altered cell cycle phenotype, which is rescued by overexpression of murine cyclins D1, D2, or D3 but not by a mutant cyclin D1.

CCND3 CCND1 CCND2

7.47e-0936939099742
Pubmed

Distinct patterns of expression of the D-type cyclins during testicular development in the mouse.

CCND3 CCND1 CCND2

2.99e-0846937537638
Pubmed

FGF2 and insulin signaling converge to regulate cyclin D expression in multipotent neural stem cells.

CCND3 CCND1 CCND2

2.99e-08469324155149
Pubmed

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle.

CCND3 CCND1 CCND2

2.99e-0846931827757
Pubmed

Negative regulation of TSC1-TSC2 by mammalian D-type cyclins.

CCND3 CCND1 CCND2

2.99e-08469316357142
Pubmed

Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1.

CCND3 CCND1 CCND2

2.99e-0846938887674
Pubmed

The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.

CCND3 CCND1 CCND2

2.99e-08469316287839
Pubmed

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation.

CCND3 CCND1 CCND2

2.99e-08469324876129
Pubmed

G1-phase regulators, cyclin D1, cyclin D2, and cyclin D3: up-regulation at gastrulation and dynamic expression during neurulation.

CCND3 CCND1 CCND2

2.99e-0846939603423
Pubmed

HLA-B2702 (77-83/83-77) peptide binds to beta-tubulin on human NK cells and blocks their cytotoxic capacity.

TUBB4A TUBB4B TUBB

2.99e-08469311120798
Pubmed

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

TUBB4A TUBB4B TUBB

2.99e-08469319545277
Pubmed

A unique function for cyclin D3 in early B cell development.

CCND3 CCND1 CCND2

2.99e-08469316582912
Pubmed

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells.

CCND3 CCND1 CCND2

2.99e-08469327129404
Pubmed

D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL.

CCND3 CCND1 CCND2

7.45e-08569325087893
Pubmed

Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.

CCND3 CCND1 CCND2

7.45e-0856931386336
Pubmed

Genomic organization, chromosomal localization, and independent expression of human cyclin D genes.

CCND3 CCND1 CCND2

7.45e-0856931386335
Pubmed

Identification of G1 kinase activity for cdk6, a novel cyclin D partner.

CCND3 CCND1 CCND2

7.45e-0856938114739
Pubmed

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.

CCND3 CCND1 CCND2

7.45e-08569311809706
Pubmed

A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95.

CCND3 CCND1 CCND2

7.45e-08569314641107
Pubmed

Essential role for cyclin D3 in granulocyte colony-stimulating factor-driven expansion of neutrophil granulocytes.

CCND3 CCND1 CCND2

7.45e-08569316954383
Pubmed

Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates.

CCND3 CCND1 CCND2

7.45e-08569322395070
Pubmed

In vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3.

CCND3 CCND1 CCND2

7.45e-08569311311237
Pubmed

Schizophrenia susceptibility gene product dysbindin-1 regulates the homeostasis of cyclin D1.

CCND3 CCND1 CCND2

7.45e-08569327130439
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

TUBB4A ARID4B TUBB CAMSAP2 RYR2 TP53BP1 RYR3

1.09e-0719169720195357
Pubmed

USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates.

CCND1 USP21 CCND2

1.49e-07669334425107
Pubmed

Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.

CCND3 CCND1 CCND2

1.49e-07669337000627
Pubmed

STAT3 down-regulates the expression of cyclin D during liver development.

CCND3 CCND1 CCND2

1.49e-07669312147685
Pubmed

Rescue of cyclin D1 deficiency by knockin cyclin E.

CCND3 CCND1 CCND2

1.49e-07669310380928
Pubmed

Role of Fgf10 in cell proliferation in white adipose tissue.

CCND3 CCND1 CCND2

1.49e-07669316513252
Pubmed

CDK4 activity in mouse embryos expressing a single D-type cyclin.

CCND3 CCND1 CCND2

1.49e-07669318311721
Pubmed

Can the cardiomyocyte cell cycle be reprogrammed?

CCND3 CCND1 CCND2

1.49e-07669317362983
Pubmed

The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype.

TUBB4A TUBB4B TUBB

1.49e-0766933782288
Pubmed

Development of mice expressing a single D-type cyclin.

CCND3 CCND1 CCND2

1.49e-07669312502747
Pubmed

Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation.

CCND3 CCND1 CCND2

1.49e-07669316943274
Pubmed

Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development.

CCND3 CCND1 CCND2

1.49e-0766939784491
Pubmed

A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation.

TUBB4A TUBB4B TUBB

1.49e-07669324275654
Pubmed

Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence.

CCND3 CCND1 CCND2

1.49e-07669311360184
Pubmed

Growth suppression by p16ink4 requires functional retinoblastoma protein.

CCND3 CCND1 CCND2

1.49e-0766937603984
Pubmed

G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells.

CCND3 CCND1 CCND2

1.49e-07669328192421
Pubmed

The GATA2 transcription factor negatively regulates the proliferation of neuronal progenitors.

CCND3 CCND1 CCND2

2.60e-07769316672344
Pubmed

NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity.

CCND3 CCND1 CCND2

2.60e-07769311042687
Pubmed

Early embryonic death in mice lacking the beta-catenin-binding protein Duplin.

CCND3 CCND1 CCND2

2.60e-07769315367660
Pubmed

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice.

CCND3 CCND1 CCND2

2.60e-07769311134518
Pubmed

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.

CCND3 CCND1 CCND2

2.60e-0776938033213
Pubmed

Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

COL2A1 CCND3 CCND1 CCND2

3.25e-072969414522949
Pubmed

Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities.

TUBB4A TUBB4B TUBB

4.16e-07869323246003
Pubmed

Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).

COL2A1 SETDB2 TUBB4B FBN1 EFEMP1 CRIM1 TUBB

6.21e-0724769739238192
Pubmed

Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

CCND3 CCND1 CCND2

6.22e-07969315467835
Pubmed

Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins.

CCND3 CCND1 CCND2

6.22e-07969324793136
Pubmed

β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis.

CCND3 CCND1 CCND2

8.88e-071069321108844
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

COL2A1 FBN1 ADAMTSL2

8.88e-071069330738849
Pubmed

jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression.

CCND3 CCND1 CCND2

8.88e-071069312852854
Pubmed

The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.

CCND3 CCND1 CCND2

8.88e-071069317699765
Pubmed

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification.

COL2A1 CCND1 BGLAP

8.88e-071069319725955
Pubmed

Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b.

CCND3 TUBB4A CCND1 CCND2

1.11e-063969423341776
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

COL2A1 CCND3 CCND1 CCND2

1.11e-063969433580754
Pubmed

Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation.

CCND3 CCND1 CCND2

1.22e-061169311748145
Pubmed

Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.

CCND3 CCND1 CCND2

1.22e-061169319723764
Pubmed

The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.

CCND3 CCND1 CCND2

1.22e-061169333854239
Pubmed

The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells.

CCND3 CCND1 CCND2

1.22e-061169328009286
Pubmed

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.

PAPPA2 EFEMP1 NALF1 RAB11FIP3

1.36e-064169423509962
Pubmed

Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.

CCND3 CCND1 CCND2

1.62e-061269316537919
Pubmed

Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.

CCND3 CCND1 CCND2

1.62e-061269324876127
Pubmed

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

CCND3 CCND1 CCND2

2.11e-061369318174243
Pubmed

Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

CCND3 CCND1 CCND2

2.11e-061369319258477
Pubmed

Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation.

CCND3 CCND1 CCND2

2.11e-061369316237170
Pubmed

Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation.

COL2A1 CCND1 BGLAP

2.11e-061369312538525
Pubmed

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2.

CCND3 CCND1 CCND2

2.11e-061369311095619
Pubmed

Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.

CCND3 CCND1 CCND2

2.11e-061369318507837
Pubmed

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.

CCND3 CCND1 CCND2

2.11e-061369317409409
Pubmed

Cyclin-binding motifs are essential for the function of p21CIP1.

CCND3 CCND1 CCND2

2.11e-06136938756624
Pubmed

Cranial neural crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19(INK4d) expression during odontogenesis.

CCND3 CCND1 CCND2

2.11e-061369312941628
Pubmed

Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.

CCND3 CCND1 CCND2

2.68e-061469318281541
Pubmed

Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.

COL2A1 CCND3 CCND1 CCND2

3.30e-065169419769959
Pubmed

Interactions between Sox9 and beta-catenin control chondrocyte differentiation.

COL2A1 CCND1 BGLAP

3.34e-061569315132997
Pubmed

Transcriptional repression of p27 is essential for murine embryonic development.

CCND3 CCND1 CCND2

3.34e-061569327196371
Pubmed

Reduced expression of cyclin D2 is associated with poor recurrence-free survival independent of cyclin D1 in stage III non-small cell lung cancer.

CCND1 CCND2

3.88e-06269222534667
Pubmed

Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity.

CCND1 CCND2

3.88e-06269218585919
Pubmed

Disruption of cyclin D3 blocks proliferation of normal B-1a cells, but loss of cyclin D3 is compensated by cyclin D2 in cyclin D3-deficient mice.

CCND3 CCND2

3.88e-06269216818732
Pubmed

The critical role of cyclin D2 in adult neurogenesis.

CCND1 CCND2

3.88e-06269215504908
Pubmed

Deregulation of D-type cyclins in uterine cancers. Cyclin D1/D3 is differentially expressed in cervical cancer.

CCND3 CCND1

3.88e-06269214666699
Pubmed

Functional analysis of the human cyclin D2 and cyclin D3 promoters.

CCND3 CCND2

3.88e-0626928621559
Pubmed

CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma.

CCND3 CCND2

3.88e-06269230538135
Pubmed

Prognostic role of cyclin D2/D3 in multiple human malignant neoplasms: A systematic review and meta-analysis.

CCND3 CCND2

3.88e-06269230950241
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

3.88e-0626928898078
Pubmed

CCND2 rearrangements are the most frequent genetic events in cyclin D1(-) mantle cell lymphoma.

CCND1 CCND2

3.88e-06269223255553
Pubmed

Activation of cyclin D1 and D2 promoters by human T-cell leukemia virus type I tax protein is associated with IL-2-independent growth of T cells.

CCND1 CCND2

3.88e-06269211992406
Pubmed

Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents.

CCND1 CCND2

3.88e-06269211872634
Pubmed

Small interfering RNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines.

CCND1 CCND2

3.88e-06269221745168
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

3.88e-06269214550562
Pubmed

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells.

CCND3 CCND2

3.88e-06269233332554
InteractionDMTF1 interactions

CCND3 CCND1 CCND2

6.21e-0611693int:DMTF1
GeneFamilyRing finger proteins

RAG1 RNF181 MARCHF6 DTX2 TRIM6 RNF217 RNF24 RNF115

1.27e-0627553858
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

2.52e-053532287
GeneFamilyTubulins

TUBB4A TUBB4B TUBB

5.90e-0526533778
GeneFamilyCyclins

CCND3 CCND1 CCND2

7.40e-0528533473
GeneFamilyAT-rich interaction domain containing

KDM5B ARID4B

8.64e-0415532418
GeneFamilyEF-hand domain containing

MACF1 RYR2 RYR3 RAB11FIP3

3.86e-03219534863
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETDB2 SMYD1

4.45e-0334532487
GeneFamilyAnkyrin repeat domain containing

SHANK2 ANKRD55 ACAP3 TP53BP2

5.49e-03242534403
GeneFamilyCollagens

COL2A1 COL6A6

8.04e-0346532490
CoexpressionBAKER_HEMATOPOESIS_STAT5_TARGETS

CCND3 CCND1 CCND2

6.06e-077693M1165
CoexpressionBAKER_HEMATOPOESIS_STAT5_TARGETS

CCND3 CCND1 CCND2

6.06e-077693MM1110
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

RSBN1 KDM5B SETX NALF1 CRIM1 MARCHF6 MACF1 CCND1 CAMSAP2 TP53BP1 TP53BP2 SNX13

2.17e-068566912M4500
CoexpressionNABA_CORE_MATRISOME

COL2A1 CRELD1 FBN1 EFEMP1 CRIM1 COL6A6 BGLAP

7.12e-06270697MM17057
CoexpressionBAKER_HEMATOPOIESIS_STAT3_TARGETS

CCND3 CCND1 CCND2

7.77e-0615693M1163
CoexpressionBAKER_HEMATOPOIESIS_STAT3_TARGETS

CCND3 CCND1 CCND2

7.77e-0615693MM1109
CoexpressionNABA_CORE_MATRISOME

COL2A1 CRELD1 FBN1 EFEMP1 CRIM1 COL6A6 BGLAP

8.03e-06275697M5884
CoexpressionNABA_MATRISOME

COL2A1 PAPPA2 CRELD1 FBN1 EFEMP1 CRIM1 COL6A6 ADAMTS9 MUC19 ADAMTSL2 BGLAP

6.09e-0510086911MM17056
CoexpressionNABA_MATRISOME

COL2A1 PAPPA2 CRELD1 FBN1 EFEMP1 CRIM1 COL6A6 ADAMTS9 MUC19 ADAMTSL2 BGLAP

7.14e-0510266911M5889
CoexpressionPETRETTO_CARDIAC_HYPERTROPHY

FBN1 EFEMP1 CRIM1

9.85e-0534693M14043
CoexpressionGERHOLD_RESPONSE_TO_TZD_UP

CCND1 CCND2

1.02e-046692MM879
CoexpressionGERHOLD_RESPONSE_TO_TZD_UP

CCND1 CCND2

1.02e-046692M2040
CoexpressionNABA_MATRISOME_INSULINOMA

FBN1 EFEMP1

1.42e-047692MM17050
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 FBN1 EFEMP1 CRIM1 BGLAP

1.50e-04191695MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 FBN1 EFEMP1 CRIM1 BGLAP

1.69e-04196695M3008
CoexpressionGSE360_CTRL_VS_L_DONOVANI_MAC_DN

RSBN1 TUBB4B MACF1 CAMSAP2 TP53BP2

1.82e-04199695M5159
CoexpressionGSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN

TUBB4B CRIM1 TUBB CAMSAP2 TP53BP1

1.86e-04200695M4459
CoexpressionGSE19825_IL2RALOW_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP

KDM5B GIMAP8 CRIM1 CCND1 DTX2

1.86e-04200695M4301
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPROGFPL

COL2A1 FANCB FBN1 TSPAN18 LRP2 CCND1

2.05e-04322696M39060
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000

TET2 RSBN1 TMEM174 DDAH1 TSPAN18 ADAMTS9 LRP2 TRIM6 CAMSAP2 RYR2 RYR3 RAB11FIP3

4.56e-067586812gudmap_developingKidney_e15.5_Proximal Tubules_1000
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000

TET2 DDAH1 TSPAN18 ADAMTS9 LRP2 RYR3 RAB11FIP3

3.14e-05280687gudmap_developingKidney_e15.5_Proximal Tubules_1000_k5
CoexpressionAtlasalpha beta T cells, T.4int8+.Th, 4int 8+ TCRhi, Thymus, avg-3

KDM5B SETX GIMAP8 ARHGEF1 ANKRD55 ADAMTSL2 CCND2

3.84e-05289687GSM399367_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000

RSBN1 CRELD1 SIN3B TMEM174 DDAH1 TSPAN18 LRP2 MACF1 CCND1 CAMSAP2 BGLAP

4.95e-058116811gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

COL2A1 RSBN1 CRELD1 DDAH1 MARCHF6 CCND1 TP53BP1

1.27e-04350687Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#4_top-relative-expression-ranked_500

TMEM174 DDAH1 TSPAN18 LRP2

1.91e-0489684gudmap_developingKidney_e15.5_S-shaped body_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_1000

SETX TSPAN18 ADAMTS9 CAMSAP2

2.08e-0491684DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000

RSBN1 TMEM174 LRP2 CAMSAP2 CCND2

2.33e-04173685gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#4_top-relative-expression-ranked_1000

TMEM174 DDAH1 TSPAN18 LRP2 RYR2

2.33e-04173685gudmap_developingKidney_e15.5_early proxim tubul_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_1000

TMEM174 DDAH1 TSPAN18 LRP2 BGLAP

2.53e-04176685gudmap_developingKidney_e15.5_S-shaped body_1000_k3
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 MST1R EFEMP1 COL6A6 SMYD1 LRP2 PNOC

1.18e-08178697bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 MST1R EFEMP1 COL6A6 SMYD1 LRP2 PNOC

1.18e-08178697c413861148129be1ee94f2ceb5999840217eebe5
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 EFEMP1 COL6A6 SMYD1 LRP2 PNOC

3.44e-07178696a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 EFEMP1 COL6A6 SMYD1 LRP2 PNOC

3.91e-071826969966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PAPPA2 EFEMP1 COL6A6 SMYD1 LRP2 PNOC

4.04e-07183696274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PAPPA2 EFEMP1 CRIM1 COL6A6 SMYD1 PNOC

4.17e-07184696607b55022de21ddb6a2d75e085df76df7abf6624
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCND3 PAPPA2 EFEMP1 NALF1 RNF24 RYR3

4.88e-07189696e059be2965cca70ff5576df055d0af1775b76e00
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB4A FBN1 EFEMP1 MACF1 ARHGEF17 ADAMTSL2

5.04e-0719069600fd993675faf53adf985b9316a18c8a33242029
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB4A FBN1 EFEMP1 MACF1 ARHGEF17 ADAMTSL2

5.04e-071906968cda09d761c6b504a744959d587c183f94f1beeb
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

KDM5B FBN1 NALF1 ADAMTS9 TUBB RYR2

6.60e-071996965b9d355795dd03a22f0961dfd143425c367a4654
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

SETX EFEMP1 TUBB MACF1 CCND1 ADAMTSL2

6.60e-0719969611c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAG1 KCNG2 DDAH1 TSPAN18 CCND2

6.71e-0617069514aa86a4f526ed6986afcb28c49225522055550c
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFEMP1 CRIM1 COL6A6 SMYD1 PNOC

7.51e-06174695a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 EFEMP1 COL6A6 LRP2 PNOC

7.51e-061746954da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 EFEMP1 CRIM1 LRP2 PNOC

7.94e-061766958e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 EFEMP1 CRIM1 LRP2 PNOC

7.94e-06176695ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

FBN1 COL6A6 RYR2 ADAMTSL2 PNOC

8.62e-06179695e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 RNF181 LRP2 RAB11FIP3

9.34e-06182695bdeebbfffc1308a29b721a5f8fed23a28d7a2f2f
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX GIMAP8 CRIM1 MACF1 CCND2

9.34e-06182695e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX GIMAP8 CRIM1 MACF1 CCND2

9.34e-061826951710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 CCND1 RAB11FIP3

9.59e-0618369592f54c267135cb5edbcacd26a0f29e62469bb7e5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 CCND1 RAB11FIP3

9.59e-061836955c4f7d02ba3a3c4a22ac71302e7c9a47e205eef5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 CRIM1 COL6A6 PPP1R15A CCND2

9.85e-0618469594748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 CRIM1 COL6A6 PPP1R15A CCND2

9.85e-06184695819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

CRIM1 ADAMTS9 ARHGEF17 RYR2 ADAMTSL2

1.01e-051856954905adaeeffd353e089578e5ea614437dbe794e6
ToppCellP15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND3 DDAH1 TSPAN18 CCND1 CCND2

1.06e-0518769560f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

FBN1 COL6A6 MACF1 RYR2 ADAMTSL2

1.06e-0518769592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellP15-Endothelial-unknown_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCND3 DDAH1 TSPAN18 CCND1 CCND2

1.06e-05187695d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARID4B MARCHF6 MACF1 TP53BP1 TP53BP2

1.09e-05188695ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

DDAH1 CRIM1 MACF1 RYR2 RYR3

1.09e-0518869534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

CCND3 TUBB4B TUBB CCND1 CCND2

1.12e-05189695311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB4A FBN1 EFEMP1 MACF1 ADAMTSL2

1.18e-05191695094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB4A FBN1 EFEMP1 MACF1 ADAMTSL2

1.18e-0519169580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB4A FBN1 EFEMP1 MACF1 ADAMTSL2

1.18e-051916955c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CRIM1 COL6A6 MACF1 RYR2 ADAMTSL2

1.24e-051936955896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 KDM5B ARID4B MACF1 CCND2

1.27e-05194695e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FBN1 NALF1 COL6A6 RYR2 ADAMTSL2

1.27e-0519469535f132cc38ac133be01834ed0946188aa0757eb4
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 COL6A6 MACF1 RYR2 ADAMTSL2

1.30e-05195695df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 COL6A6 MACF1 RYR2 ADAMTSL2

1.30e-051956954243190ad291d56694e2155954dbaa879c9d3844
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 DDAH1 CCND1 GP2 CCND2

1.30e-05195695b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

FBN1 CRIM1 COL6A6 RYR2 ADAMTSL2

1.30e-05195695aa0add081881d349099d12efca5cdee098038d4e
ToppCellIPF-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

RSBN1 PRORP ANKRD55 RYR2 TP53BP2

1.34e-051966956e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell(01)_Cycling_Basal_(homeostasis)-(0)_uninjured|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

TUBB4B EFEMP1

1.39e-05469269b42d11bfc5d1a856263b5d3bf618a83ca4ceeb
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RSBN1 TSPAN18 ARID4B MACF1 CCND2

1.44e-0519969506c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

EFEMP1 CRIM1 COL6A6 ARHGEF17 RYR2

1.47e-05200695bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellLPS-IL1RA-Endothelial-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP2 CCND1 TRIM6 ANKRD55

3.19e-05116694cf4e3c34570f57502ec524881d351ef8e47976d2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAPPA2 KCNG2 CRIM1 RYR3

4.40e-051266949b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAPPA2 KCNG2 CRIM1 RYR3

5.60e-05134694cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAG1 ANKRD55 BGLAP PNOC

5.93e-051366949cf076597e6fd9390850fda259daa13022f15893
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAG1 ANKRD55 RYR3 PNOC

8.45e-0514969410ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 RYR2 RYR3

1.11e-04160694c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 RYR2 RYR3

1.11e-0416069425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 MUC19 RYR2 GP2

1.14e-04161694b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 MUC19 RYR2 GP2

1.14e-04161694f7a89c481f789f624102857be722c95fbeb47595
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

NALF1 SHANK2 CAMSAP2 ANKRD55

1.14e-041616945f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNG2 SHANK2 PPP1R15A TP53BP1

1.14e-041616940d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 DDAH1 RNF217 RNF115

1.17e-041626941f1b93394b1f27cbb76b369c19b9313609edd577
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 NALF1 RNF24 RYR3

1.17e-04162694373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

FBN1 MACF1 ADAMTSL2 RYR3

1.19e-04163694f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAG1 DDAH1 ANKRD55 CCND2

1.19e-04163694ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5B RNF24 ACAP3 ZNF639

1.22e-04164694b77995958c938e10a526118f75d78cee72e0b207
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFEMP1 COL6A6 SMYD1 LRP2

1.31e-04167694c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAG1 DDAH1 ANKRD55 PNOC

1.31e-041676941c1b4722c6c0eff85a9b32ca7b4e281caebf63b0
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFEMP1 COL6A6 SMYD1 LRP2

1.31e-04167694351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DDAH1 FBN1 ANKRD55 PNOC

1.34e-04168694f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCellmetastatic_Lymph_Node-T/NK_cells-Exhausted_Tfh|metastatic_Lymph_Node / Location, Cell class and cell subclass

KDM5B RYR2 BGLAP CCND2

1.37e-04169694ad9054ee09033b648a76baf1b2ec4a6ab1394bde
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNG2 EFEMP1 ADAMTS9 PNOC

1.40e-04170694667443062882642211ad116043775ef8eda38859
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFEMP1 CRIM1 SMYD1 PNOC

1.50e-0417369430d67738633493d47f06ae452424382f069b6c0a
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 TUBB4A MACF1 SNX13

1.57e-041756941ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellfacs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB4B EFEMP1 CCND1 CCND2

1.57e-0417569421542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIN3B EFEMP1 GIMAP8 SPDYE3

1.60e-041766945d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNG2 EFEMP1 ANKRD55 PNOC

1.64e-04177694fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS9 CCND1 ARHGEF17 RYR2

1.68e-04178694e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCelldroplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP8 CRIM1 MACF1 CCND2

1.68e-041786948aef208b6351143562c87715bb11628880abce94
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBN1 GIMAP8 NALF1 ADAMTS9

1.71e-041796941ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNG2 TSPAN18 TRIM6 RYR3

1.75e-04180694a499548391e6833b78f6e920f8e32a755814a9da
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 ADAMTS9 LRP2 RYR2

1.75e-04180694af2bafcd1b2082629de3ea336711add01565c4c4
ToppCelldroplet-Kidney|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 RAB11FIP3

1.75e-041806947e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 ADAMTS9 LRP2 RYR2

1.75e-04180694f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 MUC19 LRP2 GP2

1.75e-0418069472310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 RAB11FIP3

1.79e-04181694bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 RAB11FIP3

1.79e-04181694cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 RYR2 ADAMTSL2 GP2

1.79e-04181694c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FBN1 NALF1 COL6A6 RYR2

1.79e-041816949ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCND3 PAPPA2 NALF1 RNF24

1.79e-0418169422363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 NALF1 RNF24 GP2

1.82e-04182694a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 EFEMP1 MACF1 ADAMTSL2

1.82e-0418269419c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 CRIM1 COL6A6 CCND2

1.82e-04182694ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 RAB11FIP3

1.82e-04182694faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHANK2 CRIM1 CCND1 DTX2

1.82e-04182694215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM174 DDAH1 LRP2 RAB11FIP3

1.82e-04182694be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCellBasal|World / shred by cell class for mouse tongue

EFEMP1 CRIM1 CCND1 CCND2

1.86e-04183694c6729a207526ff4aa48176207b9353176f631fea
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TET2 CRIM1 ADAMTS9 RYR3

1.86e-04183694eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

CRIM1 ADAMTS9 ARHGEF17 RYR2

1.86e-04183694fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP2 RYR2 RYR3

1.90e-041846942cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFEMP1 COL6A6 ARHGEF17 RYR2

1.90e-04184694689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCND3 PAPPA2 NALF1 RNF24

1.90e-04184694d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP2 RYR2 RYR3

1.90e-04184694ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP2 RYR2 RYR3

1.90e-041846942b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DDAH1 NALF1 SHANK2 CCND1

1.90e-04184694102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
DrugAC1O5Y0F

TUBB4A TUBB4B ARID4B TUBB

4.46e-0637684CID006442852
DrugEpothilone D

TUBB4A TUBB4B TUBB

5.50e-0612683DB01873
Drugdineolignan

CCND3 CCND1 CCND2

5.50e-0612683CID005316907
DrugEpothilone B

TUBB4A TUBB4B TUBB

5.50e-0612683DB03010
DrugABT-751

TUBB4A TUBB4B TUBB PNOC

9.03e-0644684CID003035714
Drug2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone

CCND3 CCND1 CCND2

1.13e-0515683ctd:C120275
Druggalgravin

CCND3 CCND1 CCND2

1.39e-0516683CID000101749
DrugCPG-oligonucleotide

CCND3 FANCB SETX ATRIP TP53BP1 CCND2

1.85e-05184686ctd:C408982
Drug2-hydroxycarbazole

RYR2 RYR3

2.63e-053682CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

2.63e-053682CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

2.63e-053682CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

2.63e-053682CID005748312
Drug8N3-cADPR

RYR2 RYR3

2.63e-053682CID000127713
Drugaminodantrolene

RYR2 RYR3

2.63e-053682CID009570289
DrugBerberine

COL2A1 SETDB2 KDM5B CCND1 BGLAP CCND2

3.14e-05202686ctd:D001599
Drugbromocolchicine

TUBB4A TUBB4B TUBB

3.26e-0521683CID000161518
DrugUstiloxin A

TUBB4A TUBB4B TUBB

3.26e-0521683CID000164454
DrugSRI-3072

TUBB4A TUBB4B TUBB

3.26e-0521683CID000493469
Drugcolchifoline

TUBB4A TUBB4B TUBB

3.26e-0521683CID000100132
Drug3,4,5-trimethoxyacetophenone

TUBB4A TUBB4B TUBB

3.77e-0522683CID000014345
DrugAC1L1GIQ

TUBB4A TUBB4B TUBB

3.77e-0522683CID000003700
Drug2,4-dichlorobenzyl thiocyanate

TUBB4A TUBB4B TUBB

3.77e-0522683CID000098538
DrugSureCN13401588

TUBB4A TUBB4B TUBB

3.77e-0522683CID009897422
Drugdi-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone

CCND3 CCND1 CCND2

3.77e-0522683ctd:C539263
DrugN-methyldemecolcine

TUBB4A TUBB4B TUBB

3.77e-0522683CID000023759
DrugNSC-339672

TUBB4A TUBB4B TUBB

3.77e-0522683CID000433930
DrugThapsigargin

CRELD1 TUBB4A TUBB4B DDAH1 ARID4B ADAMTS9 RNF181 TUBB MACF1 CCND1 PRORP PPP1R15A TAF1L TP53BP2

3.83e-0513536814ctd:D019284
DrugIKP104

TUBB4A TUBB4B TUBB

4.32e-0523683CID000130739
Drugfluorescein-colchicine

TUBB4A TUBB4B TUBB

4.32e-0523683CID003035871
Drug3,4,5-trimethoxybenzaldehyde

TUBB4A TUBB4B TUBB

4.32e-0523683CID000006858
Drug3-demethylthiocolchicine

TUBB4A TUBB4B TUBB

4.32e-0523683CID000084076
Drug2,3,4-TCB

TUBB4A TUBB4B TUBB

4.32e-0523683CID000129239
DrugAC1L2P05

TUBB4A TUBB4B TUBB

4.32e-0523683CID000125688
Drug2,3,4-tabp

TUBB4A TUBB4B TUBB

4.32e-0523683CID000125548
DrugNSC-373301

TUBB4A TUBB4B TUBB

4.32e-0523683CID000341375
DrugN-acetylcolchinol

TUBB4A TUBB4B TUBB

4.32e-0523683CID000097865
DrugNSC355636

TUBB4A TUBB4B TUBB

4.32e-0523683CID000100176
Drugmoscatilin

TUBB4A TUBB4B TUBB

4.93e-0524683CID000176096
Drugparbendazole

TUBB4A TUBB4B TUBB

4.93e-0524683CID000026596
DrugNSC-36768

TUBB4A TUBB4B TUBB

4.93e-0524683CID000165441
Drugdeacetamidocolchicine

TUBB4A TUBB4B TUBB

4.93e-0524683CID000014995
Drugtropolone methyl ether

TUBB4A TUBB4B TUBB

4.93e-0524683CID000016546
Drug7-epi-cephalomannine

TUBB4A TUBB4B TUBB

4.93e-0524683CID000330401
DrugNABV

TUBB4A TUBB4B TUBB

4.93e-0524683CID000175959
Drugcolchicide

TUBB4A TUBB4B TUBB

4.93e-0524683CID000120712
DrugAC1L4TG7

TUBB4A TUBB4B TUBB

4.93e-0524683CID000163705
DrugTHRX 165724

CCND3 CCND2

5.25e-054682ctd:C475928
DrugPCB74

RYR2 RYR3

5.25e-054682CID000036218
Drug148504-47-6

RYR2 RYR3

5.25e-054682CID006444275
Drug5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

CCND3 CCND2

5.25e-054682ctd:C513935
DrugSC 38249

RYR2 RYR3

5.25e-054682CID000134834
DrugAC1L1U7A

RYR2 RYR3

5.25e-054682CID000035682
DrugCyl-2

CCND1 CCND2

5.25e-054682CID000162495
Drugixabepilone

TUBB4A TUBB4B TUBB PNOC

5.43e-0569684CID006445540
DrugNBD-colcemid

TUBB4A TUBB4B TUBB

5.59e-0525683CID000130594
DrugmpMap

TUBB4A TUBB4B TUBB

5.59e-0525683CID000100806
DrugAC1Q6P06

TUBB4A TUBB4B TUBB

5.59e-0525683CID000160263
Drug2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone

TUBB4A TUBB4B TUBB

5.59e-0525683CID000043264
Drugallocolchicine

TUBB4A TUBB4B TUBB

5.59e-0525683CID000196989
Drug1069C85

TUBB4A TUBB4B TUBB

5.59e-0525683CID006918099
Drug55623-37-5

TUBB4A TUBB4B TUBB

5.59e-0525683CID006438440
DrugCA1P

TUBB4A TUBB4B TUBB

5.59e-0525683CID006918545
Drugpeloruside A

TUBB4A TUBB4B TUBB

5.59e-0525683CID006918506
DrugNSC142227

TUBB4A TUBB4B TUBB

5.59e-0525683CID000073427
DrugMDL 27048

TUBB4A TUBB4B TUBB

5.59e-0525683CID006439188
DrugNSC527981

TUBB4A TUBB4B TUBB

6.31e-0526683CID000352796
DrugNSC332029

TUBB4A TUBB4B TUBB

6.31e-0526683CID000100073
Drugindibulin

TUBB4A TUBB4B TUBB

6.31e-0526683CID000002929
Drugpironetin

TUBB4A TUBB4B TUBB

6.31e-0526683CID006438891
Drugisaxonine

TUBB4A TUBB4B TUBB

6.31e-0526683CID000071169
DrugAC1L1J4H

TUBB4A TUBB4B TUBB

7.08e-0527683CID000004862
DrugEverolimus

CCND3 CCND1 CCND2

7.08e-0527683ctd:D000068338
DrugNSC292222

TUBB4A TUBB4B TUBB

7.08e-0527683CID000099957
Drugdinitroanilines

TUBB4A TUBB4B TUBB

7.08e-0527683CID000136400
DrugNSC D-669356

TUBB4A TUBB4B TUBB

7.08e-0527683CID000178028
DrugNSC 370147

TUBB4A TUBB4B TUBB

7.91e-0528683CID000182762
DrugNSC72302

TUBB4A TUBB4B TUBB

7.91e-0528683CID000118078
Drugbp U

TUBB4A TUBB4B TUBB

8.81e-0529683CID000368697
DrugAids106696

TUBB4A TUBB4B TUBB

8.81e-0529683CID006475933
DrugddGDP

TUBB4A TUBB4B TUBB

8.81e-0529683CID000134739
Drugoxibendazole

TUBB4A TUBB4B TUBB

8.81e-0529683CID000004622
Drugprocaine

TUBB4A TUBB4B TUBB RYR2 RYR3

9.51e-05153685CID000004914
Drug2,4-xylidinothiazoline

COL2A1 RYR2 RYR3

9.76e-0530683CID000099296
DrugAC1NBBHE

TUBB4A TUBB4B TUBB

9.76e-0530683CID004490620
Drugeleutherobin

TUBB4A TUBB4B TUBB

9.76e-0530683CID006918335
Drugazatoxin

TUBB4A TUBB4B TUBB

9.76e-0530683CID000125383
DrugNSC617668

TUBB4A TUBB4B TUBB

9.76e-0530683CID000357989
Drugcitostal

TUBB4A TUBB4B TUBB

9.76e-0530683CID000018991
Drugthiocolchicine

TUBB4A TUBB4B TUBB

9.76e-0530683CID000017648
Drugtropone

TUBB4A TUBB4B TUBB

1.08e-0431683CID000010881
DrugNSC609395

TUBB4A TUBB4B TUBB

1.08e-0431683CID005488798
Drugamiprophosmethyl

TUBB4A TUBB4B TUBB

1.08e-0431683CID000100524
DrugAC7700

TUBB4A TUBB4B TUBB

1.08e-0431683CID006918404
Drug3,4-dimethylhexane-2,5-dione

TUBB4A TUBB4B TUBB

1.08e-0431683CID000032851
DrugAC1L3V8I

TUBB4A TUBB4B TUBB

1.08e-0431683CID000122777
DrugNSC332598

TUBB4A TUBB4B TUBB

1.08e-0431683CID000615942
DrugN,N'-ethylenebis(iodoacetamide

TUBB4A TUBB4B TUBB

1.08e-0431683CID000023678
DrugAC1L1G95

TUBB4A TUBB4B TUBB

1.19e-0432683CID000003583
DrugE2-3,4-Q

TUBB4A TUBB4B TUBB

1.19e-0432683CID000067402
DrugNSC153858

TUBB4A TUBB4B TUBB

1.19e-0432683CID000547450
Diseasecolon adenoma (is_marker_for)

TET2 CCND1 CCND2

4.07e-077683DOID:0050912 (is_marker_for)
Diseasehypokalemic periodic paralysis (implicated_via_orthology)

TUBB4A TUBB4B TUBB

6.50e-078683DOID:14452 (implicated_via_orthology)
Diseasefacial paralysis (implicated_via_orthology)

TUBB4A TUBB4B TUBB

1.39e-0610683DOID:13934 (implicated_via_orthology)
Diseasecomplex cortical dysplasia with other brain malformations 7 (implicated_via_orthology)

TUBB4A TUBB4B TUBB

1.39e-0610683DOID:0090132 (implicated_via_orthology)
Diseaseptosis (implicated_via_orthology)

TUBB4A TUBB4B TUBB

1.39e-0610683DOID:0060260 (implicated_via_orthology)
Diseasetubulinopathy (implicated_via_orthology)

TUBB4A TUBB4B TUBB

1.39e-0610683DOID:0112227 (implicated_via_orthology)
Diseasecerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)

TUBB4A TUBB4B TUBB

2.54e-0612683DOID:0050997 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

1.57e-053682DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

1.57e-053682DOID:8545 (implicated_via_orthology)
Diseasepeak expiratory flow

COL2A1 PAPPA2 TET2 TMEM174 EFEMP1 NALF1 ARHGEF17 CCND2

1.89e-05498688EFO_0009718
Diseaseinvasive lobular carcinoma (is_implicated_in)

CCND1 CCND2

3.13e-054682DOID:3457 (is_implicated_in)
DiseaseGeleophysic dysplasia

FBN1 ADAMTSL2

5.21e-055682C3489726
DiseaseAcromicric Dysplasia

FBN1 ADAMTSL2

5.21e-055682C0265287
Diseasemultiple myeloma (is_marker_for)

CCND3 CCND1 CCND2

7.91e-0536683DOID:9538 (is_marker_for)
Diseasebirth weight, parental genotype effect measurement

PAPPA2 TET2 USF3 CCND1 CCND2

8.28e-05192685EFO_0004344, EFO_0005939
Diseasehigh grade glioma (is_marker_for)

KDM5B EFEMP1 CCND1

1.26e-0442683DOID:3070 (is_marker_for)
Diseaseserum IgG glycosylation measurement

USF3 EFEMP1 SMYD1 TRIM6 ANKRD55 RYR2 PNOC

2.01e-04523687EFO_0005193
Diseasesexual dimorphism measurement

CCND3 PAPPA2 TET2 FBN1 EFEMP1 CRIM1 MACF1 TP53BP1 SNX13 CCND2

2.12e-0411066810EFO_0021796
DiseaseSensory hearing loss

COL2A1 LRP2

2.84e-0411682C1691779
DiseaseColonic Neoplasms

KDM5B CCND1 TP53BP1 CCND2

4.27e-04152684C0009375
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

PAPPA2 ARHGEF17

4.68e-0414682EFO_0004307, EFO_0008464
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

MACF1 TP53BP1 SNX13

5.05e-0467683EFO_0008595, EFO_0020946
DiseaseMalignant tumor of colon

KDM5B CCND1 TP53BP1 CCND2

5.06e-04159684C0007102
DiseaseProstatic Neoplasms

TET2 RAG1 LRP2 CCND1 TAF1L BGLAP CCND2

5.38e-04616687C0033578
DiseaseMalignant neoplasm of prostate

TET2 RAG1 LRP2 CCND1 TAF1L BGLAP CCND2

5.38e-04616687C0376358
Diseasenasopharynx carcinoma (is_implicated_in)

TET2 MST1R

5.39e-0415682DOID:9261 (is_implicated_in)
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

FANCB CCND1

5.39e-0415682DOID:5520 (is_implicated_in)
DiseaseCrohn's disease

CCND3 RSBN1 TMEM174 MUC19 PRORP ANKRD55

5.39e-04441686EFO_0000384
Diseasetotal blood protein measurement

CCND3 CRIM1 MACF1 ANKRD55 SNX13 CCND2

5.93e-04449686EFO_0004536
DiseaseSchwartz-Jampel Syndrome, Type 1

COL2A1 ADAMTSL2

6.15e-0416682C4551479
DiseaseSpondyloepiphyseal Dysplasia

COL2A1 ADAMTSL2

6.15e-0416682C0038015
DiseaseSchwartz-Jampel Syndrome

COL2A1 ADAMTSL2

6.15e-0416682C0036391
DiseaseMelnick-Needles Syndrome

COL2A1 ADAMTSL2

6.15e-0416682C0025237
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

COL2A1 ADAMTSL2

6.15e-0416682C3541456
Diseasebody surface area

CCND3 PAPPA2 DDAH1 FBN1 EFEMP1 CRIM1 MACF1

6.93e-04643687EFO_0022196
DiseaseVan Buchem disease

COL2A1 ADAMTSL2

6.96e-0417682C0432272
Diseasecentral corneal thickness

TET2 FBN1 EFEMP1 CRIM1 CCND2

7.41e-04309685EFO_0005213
Diseasehepatocellular carcinoma (is_implicated_in)

TET2 CCND1 RYR3 CCND2

8.21e-04181684DOID:684 (is_implicated_in)
DiseaseDyschondroplasias

COL2A1 ADAMTSL2

8.72e-0419682C0013366
DiseaseOsteochondrodysplasias

COL2A1 ADAMTSL2

8.72e-0419682C0029422
Diseasemacula measurement

COL2A1 FBN1 ADAMTS9 LRP2

9.64e-04189684EFO_0008375
DiseaseMultiple Epiphyseal Dysplasia

COL2A1 ADAMTSL2

9.68e-0420682C0026760
DiseaseColorectal Carcinoma

TET2 EFEMP1 ARHGEF1 LRP2 CCND1 CAMSAP2 CCND2

1.15e-03702687C0009402
Diseaseimpotence (biomarker_via_orthology)

CCND1 CCND2

1.17e-0322682DOID:1875 (biomarker_via_orthology)
DiseaseNasopharyngeal carcinoma

MST1R CCND1

1.17e-0322682C2931822
DiseaseSensorineural Hearing Loss (disorder)

COL2A1 LRP2

1.28e-0323682C0018784
Diseasealpha fetoprotein measurement

SETDB2 SETX TP53BP1

1.61e-03100683EFO_0010583
DiseaseHeart valve disease

ADAMTSL2 BGLAP

1.64e-0326682C0018824
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

MACF1 TP53BP1 SNX13

1.76e-03103683EFO_0008595, EFO_0020944
Diseaselean body mass

CCND3 TET2 MST1R EFEMP1 PRORP

1.83e-03379685EFO_0004995
DiseaseHyperplasia

COL2A1 CCND1

1.90e-0328682C0020507
Diseaseosteoarthritis (is_implicated_in)

COL2A1 BGLAP

1.90e-0328682DOID:8398 (is_implicated_in)
Diseasehandedness

TUBB4A ARHGEF1 TUBB

1.91e-03106683EFO_0009902
Diseaseurinary bladder cancer (is_marker_for)

CCND3 KDM5B CCND1

1.96e-03107683DOID:11054 (is_marker_for)
Diseaseforced expiratory volume

TET2 EFEMP1 CRIM1 ARHGEF1 ARHGEF17 RYR2 SNX13

2.24e-03789687EFO_0004314
Diseasealkaline phosphatase measurement

TET2 RSBN1 ATRIP MACF1 TRIM6 TP53BP1 ADAMTSL2 SNX13

2.27e-031015688EFO_0004533

Protein segments in the cluster

PeptideGeneStartEntry
VVCPDCSDEIAVKKD

ARID4B

196

Q4LE39
EPTEREKVELAAECC

ARHGEF1

581

Q92888
EVCEEQRCEEEVFPL

CCND3

66

P30281
VVDDLRLCSVKPCED

ACAP3

311

Q96P50
EVCEEQKCEEEVFPL

CCND1

66

P24385
VIREDPSILECCDSE

ANKRD55

46

Q3KP44
TICRDVVDLCKEPGE

TP53BP2

26

Q13625
DIICEDVKDCLSPEI

COL2A1

66

P02458
VKCPAKECNEEVSLE

RAG1

356

P15918
CTPCLKANIERLEEE

RAB11FIP3

561

O75154
EPDVEACIAVCSARI

ARHGEF17

1536

Q96PE2
VCEEQKCEEEVFPLA

CCND2

66

P30279
SKCLDVDECETEVCP

CRELD1

301

Q96HD1
RIDCTPDQEVTEDIC

MGAM2

51

Q2M2H8
TEELKVPPDEDCIIC

DTX2

401

Q86UW9
DIRAEEERGECSPKC

KCNG2

201

Q9UJ96
DRSCDVEDVPVDGCT

MUC19

1101

Q7Z5P9
VEDKCEKACRPEEEC

GP2

186

P55259
EKECLCEEGVTPLVE

MACF1

471

O94854
EDICRVCRSEGTPEK

MARCHF6

6

O60337
CEAAEAVRPEERKTC

ADAMTSL2

666

Q86TH1
EQEKTQEERCSEPCL

GOLGA6L7

536

A0A1B0GV03
DFELLPDDERQCVKC

KDM5B

681

Q9UGL1
DKRTCVDIDECTEMP

LRP2

3146

P98164
LEVCILECEEKVFPS

PNOC

41

Q13519
REVCELNPDCDELAD

BGLAP

71

P02818
EEKECLVPLCGEEEN

FANCB

441

Q8NB91
DLDECTCRDPKAEEN

PAPPA2

1776

Q9BXP8
CVERIKPDEQRACES

ADAMTS9

1366

Q9P2N4
EDTRVCDDVNECETP

FBN1

1641

P35555
DPSRLEEEVKRCLSC

GIMAP8

506

Q8ND71
RIEEEKPDCSKARCE

CRIM1

166

Q9NZV1
LCAAETDVEDPEVEC

ATRIP

776

Q8WXE1
DDKSECPCPEEIRDQ

RYR2

1981

Q92736
CPDVVRLEDICLKET

CAMSAP2

266

Q08AD1
LPDCVFVEDVAVVCE

DDAH1

71

O94760
CSPREECKRIEVLDV

COL6A6

796

A6NMZ7
CCPAVEEEDDEEAVK

PPP1R15A

186

O75807
DPVRQQCKDIDECDI

EFEMP1

36

Q12805
CVRIKTESEEACTEI

RSBN1

736

Q5VWQ0
KEVCRDLVCTSPKDE

SNX13

206

Q9Y5W8
LECPVCKEDYTVEEE

RNF115

226

Q9Y4L5
CPVCLLEFEEEETAI

RNF181

76

Q9P0P0
TEEEIRAKVSPEQCC

TAF1L

891

Q8IZX4
LCRECLEKQEPVFAD

SMYD1

331

Q8NB12
KCDDPEEELCHRREA

SETX

2621

Q7Z333
EEDEDMVPCKTLCET

SIN3B

1126

O75182
ELCAVCLEDFKPRDE

RNF24

76

Q9Y225
EIKCPITECFEFLEE

RNF217

301

Q8TC41
DEDLVERCSCEVPTK

PRORP

561

O15091
PAECVEEVQCKPRDS

SHANK2

576

Q9UPX8
EVEEIDQCTKPRDCP

WFDC6

41

Q9BQY6
KLEVACSDCEVEVLP

SETDB2

431

Q96T68
EEELESENAPVCDRC

USP21

426

Q9UK80
DIVICDEECDSPESV

ZNF639

106

Q9UID6
IPEENRCVDILELCE

RYR3

1536

Q15413
VLDVVRKEAESCDCL

TUBB4A

116

P04350
CKRKRECLDESDDEP

SPDYE3

196

A6NKU9
VLDVVRKEAESCDCL

TUBB4B

116

P68371
VLDVVRKEAESCDCL

TUBB

116

P07437
DCVSEVEIIAEPCRV

USF3

971

Q68DE3
EETEEPIVECQECET

TP53BP1

1271

Q12888
CLPEDKEVLTEDKCL

UBA1

431

P22314
LSCQLCKESEERVPD

TMEM174

96

Q8WUU8
TLDSEEVPEACCRRE

TSPAN18

166

Q96SJ8
PSCRCVEQIIEKDEG

TET2

1131

Q6N021
TLIDEGVERCCESPV

MST1R

376

Q04912
LVDIREEVTCPICLE

TRIM6

6

Q9C030
NDEPECCDVRREEKS

NALF1

371

B1AL88