Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	CRIM1 TIE1 ROS1 FGFR3 FGFR4	6.62e-06	65	81	5	GO:0004714
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	CRIM1 TIE1 ROS1 FGFR3 FGFR4	2.47e-05	85	81	5	GO:0019199
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	NPC1 SELE OR5B3 CRIM1 TIE1 OR5AU1 IL1RAPL2 P2RY8 ROS1 FGFR3 FGFR4 F2R PLXNB2 F2RL2 IL3RA GPR132	9.13e-05	1353	81	16	GO:0004888
GeneOntologyMolecularFunction	thrombin-activated receptor activity	F2R F2RL2	1.61e-04	5	81	2	GO:0015057
GeneOntologyMolecularFunction	fibroblast growth factor receptor activity	FGFR3 FGFR4	1.61e-04	5	81	2	GO:0005007
GeneOntologyMolecularFunction	proteinase-activated receptor activity	F2R F2RL2	1.61e-04	5	81	2	GO:0001648
GeneOntologyMolecularFunction	fibroblast growth factor binding	FGFR3 FGFR4 KLB	1.75e-04	27	81	3	GO:0017134
GeneOntologyMolecularFunction	protein tyrosine kinase activity	CRIM1 TIE1 ROS1 FGFR3 FGFR4	3.10e-04	145	81	5	GO:0004713
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	AMBP SPINT2 CRIM1 WFIKKN2	8.80e-04	105	81	4	GO:0004867
GeneOntologyMolecularFunction	histone ubiquitin ligase activity	RNF20 UHRF1	1.04e-03	12	81	2	GO:0140852
GeneOntologyBiologicalProcess	eye morphogenesis	TTC8 LCTL TENM3 STAU2 DIO3 IKZF1 FGFR3	1.99e-05	204	84	7	GO:0048592
GeneOntologyCellularComponent	receptor complex	TIE1 TRA ROS1 FGFR3 FGFR4 CUBN TRAV38-2DV8 PLXNB2 IL3RA SHISA7	1.11e-04	581	84	10	GO:0043235
MousePheno	abnormal glial cell morphology	NPC1 ATRN CTSF ACP2 MDGA2 ZFYVE26 PHOX2B PLXNB2 GNS DYNC1H1 CNTN1	1.60e-06	345	73	11	MP:0003634
MousePheno	gliosis	NPC1 ATRN CTSF ACP2 MDGA2 ZFYVE26 GNS CNTN1	2.91e-06	171	73	8	MP:0002183
MousePheno	tremors	NPC1 SELE ATRN CTSF PTPN9 ACP2 MDGA2 ZFYVE26 SHISA7 DYNC1H1	1.40e-05	353	73	10	MP:0000745
MousePheno	astrocytosis	NPC1 ATRN ACP2 MDGA2 ZFYVE26 GNS	1.58e-05	103	73	6	MP:0003354
MousePheno	increased astrocyte number	NPC1 ATRN ACP2 MDGA2 ZFYVE26 GNS	1.96e-05	107	73	6	MP:0012065
MousePheno	abnormal astrocyte number	NPC1 ATRN ACP2 MDGA2 ZFYVE26 GNS	2.54e-05	112	73	6	MP:0012064
MousePheno	weight loss	NPC1 SELE CTSF PIK3CB MDGA2 GPR132 HYDIN CNTN1 ABCB4	3.39e-05	312	73	9	MP:0001263
MousePheno	small cerebellum	NPC1 TMEM67 ACP2 PLXNB2 HYDIN CNTN1	3.59e-05	119	73	6	MP:0000852
MousePheno	abnormal metencephalon morphology	NPC1 ATRN TMEM67 PHOX2A ACP2 ZFYVE26 PHOX2B PLXNB2 HYDIN CNTN1	6.16e-05	420	73	10	MP:0000847
MousePheno	abnormal CNS glial cell morphology	NPC1 ATRN ACP2 MDGA2 ZFYVE26 PLXNB2 GNS DYNC1H1	8.34e-05	272	73	8	MP:0000952
MousePheno	abnormal motor neuron morphology	PHOX2A CTSF MDGA2 ZFYVE26 PHOX2B DYNC1H1	1.35e-04	151	73	6	MP:0000937
MousePheno	abnormal astrocyte morphology	NPC1 ATRN ACP2 MDGA2 ZFYVE26 GNS	1.56e-04	155	73	6	MP:0002182
MousePheno	postnatal growth retardation	NPC1 ATRN TTC8 TMEM67 PHOX2A ZBTB20 PIK3CB ACP2 DIO3 FAR1 PHOX2B CSGALNACT1 HYDIN DYNC1H1	1.59e-04	881	73	14	MP:0001732
MousePheno	abnormal tumor necrosis factor (ligand) superfamily member 11 level	F2R ABCB4	1.60e-04	4	73	2	MP:0021028
MousePheno	abnormal sphenooccipital synchondrosis	FGFR3 CSGALNACT1	1.60e-04	4	73	2	MP:0030445
MousePheno	abnormal hindbrain morphology	NPC1 ATRN TMEM67 PHOX2A ACP2 ZFYVE26 PHOX2B PLXNB2 HYDIN CNTN1	2.01e-04	485	73	10	MP:0000841
MousePheno	abnormal nervous system development	TMEM67 PHOX2A PTPN9 ZBTB20 SPINT2 ACP2 ALG10 STAU2 UHRF1 ZFYVE26 MLST8 PHOX2B F2R PLXNB2 HYDIN DYNC1H1 CNTN1	2.02e-04	1257	73	17	MP:0003861
MousePheno	abnormal postnatal growth	NPC1 ATRN TTC8 TMEM67 PHOX2A ZBTB20 PIK3CB ACP2 DIO3 FAR1 PHOX2B CSGALNACT1 HYDIN DYNC1H1	2.15e-04	907	73	14	MP:0001731
MousePheno	absent trigeminal nerve	CRIM1 PHOX2B	2.66e-04	5	73	2	MP:0001066
MousePheno	abnormal spinal cord grey matter morphology	PHOX2A CTSF MDGA2 ZFYVE26 PHOX2B DYNC1H1	3.60e-04	181	73	6	MP:0008503
MousePheno	abnormal cranial synchondrosis	FGFR3 CSGALNACT1	3.98e-04	6	73	2	MP:0030443
Domain	Ig-like_fold	TIE1 IL1RAPL2 TRA WFIKKN2 MDGA2 ROS1 FGFR3 FGFR4 MDGA1 PLXNB2 IL3RA CNTN1	4.42e-05	706	80	12	IPR013783
Domain	Growth_fac_rcpt_	ATRN TMEM67 CRIM1 TIE1 CUBN SVEP1	5.57e-05	156	80	6	IPR009030
Domain	-	AMBP SPINT2 WFIKKN2	5.90e-05	18	80	3	4.10.410.10
Domain	Prtase_inh_Kunz-CS	AMBP SPINT2 WFIKKN2	5.90e-05	18	80	3	IPR020901
Domain	KU	AMBP SPINT2 WFIKKN2	5.90e-05	18	80	3	SM00131
Domain	BPTI_KUNITZ_2	AMBP SPINT2 WFIKKN2	6.98e-05	19	80	3	PS50279
Domain	Kunitz_BPTI	AMBP SPINT2 WFIKKN2	6.98e-05	19	80	3	PF00014
Domain	BPTI_KUNITZ_1	AMBP SPINT2 WFIKKN2	6.98e-05	19	80	3	PS00280
Domain	Protea_act_rcpt	F2R F2RL2	1.08e-04	4	80	2	IPR003912
Domain	FGF_rcpt_fam	FGFR3 FGFR4	1.08e-04	4	80	2	IPR016248
Domain	-	TIE1 IL1RAPL2 WFIKKN2 MDGA2 ROS1 FGFR3 FGFR4 MDGA1 PLXNB2 IL3RA CNTN1	1.17e-04	663	80	11	2.60.40.10
Domain	Kunitz_BPTI	AMBP SPINT2 WFIKKN2	1.26e-04	23	80	3	IPR002223
Domain	EGF_extracell	ATRN TENM3 TIE1 SVEP1	1.27e-04	60	80	4	IPR013111
Domain	EGF_2	ATRN TENM3 TIE1 SVEP1	1.27e-04	60	80	4	PF07974
Domain	Ig_I-set	WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	1.65e-04	190	80	6	IPR013098
Domain	ig	TIE1 IL1RAPL2 MDGA2 FGFR3 FGFR4 MDGA1	1.65e-04	190	80	6	PF00047
Domain	Immunoglobulin	TIE1 IL1RAPL2 MDGA2 FGFR3 FGFR4 MDGA1	1.65e-04	190	80	6	IPR013151
Domain	I-set	WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	1.65e-04	190	80	6	PF07679
Domain	GLYCOSYL_HYDROL_F1_2	LCTL KLB	1.80e-04	5	80	2	PS00653
Domain	GLYCOSYL_HYDROL_F1_1	LCTL KLB	1.80e-04	5	80	2	PS00572
Domain	Glyco_hydro_1	LCTL KLB	1.80e-04	5	80	2	PF00232
Domain	Glyco_hydro_1	LCTL KLB	1.80e-04	5	80	2	IPR001360
Domain	EGF	SELE ATRN TIE1 CUBN SVEP1	2.07e-04	126	80	5	PF00008
Domain	FN3_dom	TIE1 MDGA2 ROS1 MDGA1 IL3RA CNTN1	2.76e-04	209	80	6	IPR003961
Domain	IG	TIE1 IL1RAPL2 WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	4.38e-04	421	80	8	SM00409
Domain	Ig_sub	TIE1 IL1RAPL2 WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	4.38e-04	421	80	8	IPR003599
Domain	IGc2	WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	5.15e-04	235	80	6	SM00408
Domain	EGF_3	SELE ATRN TENM3 TIE1 CUBN SVEP1	5.15e-04	235	80	6	PS50026
Domain	Ig_sub2	WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	5.15e-04	235	80	6	IPR003598
Domain	EGF	SELE ATRN TENM3 TIE1 CUBN SVEP1	5.15e-04	235	80	6	SM00181
Domain	TyrKc	TIE1 ROS1 FGFR3 FGFR4	5.54e-04	88	80	4	SM00219
Domain	Tyr_kinase_cat_dom	TIE1 ROS1 FGFR3 FGFR4	5.54e-04	88	80	4	IPR020635
Domain	EGF-like_dom	SELE ATRN TENM3 TIE1 CUBN SVEP1	6.97e-04	249	80	6	IPR000742
Domain	EGF_1	SELE ATRN TENM3 TIE1 CUBN SVEP1	7.89e-04	255	80	6	PS00022
Domain	PROTEIN_KINASE_TYR	TIE1 ROS1 FGFR3 FGFR4	7.99e-04	97	80	4	PS00109
Domain	Tyr_kinase_AS	TIE1 ROS1 FGFR3 FGFR4	7.99e-04	97	80	4	IPR008266
Domain	EGF-like_CS	SELE ATRN TENM3 TIE1 CUBN SVEP1	8.90e-04	261	80	6	IPR013032
Domain	EGF_2	SELE ATRN TENM3 TIE1 CUBN SVEP1	9.63e-04	265	80	6	PS01186
Domain	Ig-like_dom	TIE1 IL1RAPL2 WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	1.39e-03	503	80	8	IPR007110
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DYNC1H1	1.59e-03	14	80	2	IPR024317
Domain	Dynein_HC_stalk	DNAH6 DYNC1H1	1.59e-03	14	80	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DYNC1H1	1.59e-03	14	80	2	IPR013602
Domain	DHC_N2	DNAH6 DYNC1H1	1.59e-03	14	80	2	PF08393
Domain	MT	DNAH6 DYNC1H1	1.59e-03	14	80	2	PF12777
Domain	AAA_8	DNAH6 DYNC1H1	1.59e-03	14	80	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH6 DYNC1H1	1.59e-03	14	80	2	IPR011704
Domain	AAA_5	DNAH6 DYNC1H1	1.59e-03	14	80	2	PF07728
Domain	FN3	TIE1 MDGA2 ROS1 MDGA1 CNTN1	1.64e-03	199	80	5	PS50853
Domain	DHC_fam	DNAH6 DYNC1H1	1.83e-03	15	80	2	IPR026983
Domain	Dynein_heavy_dom	DNAH6 DYNC1H1	1.83e-03	15	80	2	IPR004273
Domain	Dynein_heavy	DNAH6 DYNC1H1	1.83e-03	15	80	2	PF03028
Domain	MAM_1	MDGA2 MDGA1	2.09e-03	16	80	2	PS00740
Domain	Pkinase_Tyr	TIE1 ROS1 FGFR3 FGFR4	2.29e-03	129	80	4	PF07714
Domain	MAM	MDGA2 MDGA1	2.36e-03	17	80	2	SM00137
Domain	MAM	MDGA2 MDGA1	2.65e-03	18	80	2	PF00629
Domain	MAM_dom	MDGA2 MDGA1	2.65e-03	18	80	2	IPR000998
Domain	MAM_2	MDGA2 MDGA1	2.65e-03	18	80	2	PS50060
Domain	Ser-Thr/Tyr_kinase_cat_dom	TIE1 ROS1 FGFR3 FGFR4	2.92e-03	138	80	4	IPR001245
Pathway	REACTOME_IRS_MEDIATED_SIGNALLING	PIK3CB FGFR3 FGFR4 KLB	3.67e-05	41	65	4	MM14505
Pathway	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R	PIK3CB FGFR3 FGFR4 KLB	6.33e-05	47	65	4	MM14885
Pathway	REACTOME_IRS_MEDIATED_SIGNALLING	PIK3CB FGFR3 FGFR4 KLB	6.88e-05	48	65	4	M26916
Pathway	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE	PIK3CB FGFR3 FGFR4 KLB	6.88e-05	48	65	4	MM15441
Pathway	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R	PIK3CB FGFR3 FGFR4 KLB	1.09e-04	54	65	4	M27168
Pathway	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE	PIK3CB FGFR3 FGFR4 KLB	1.09e-04	54	65	4	M620
Pathway	REACTOME_PI3K_AKT_SIGNALING_IN_CANCER	PIK3CB FGFR3 FGFR4 MLST8 KLB	1.50e-04	110	65	5	M27162
Pathway	KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY	PIK3CB FGFR3 FGFR4	3.84e-04	31	65	3	M47396
Pathway	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	PIK3CB FGFR3 FGFR4 KLB	4.12e-04	76	65	4	MM15442
Pathway	WP_REGULATORY_CIRCUITS_OF_STAT3_SIGNALING	MLST8 F2R F2RL2 IL3RA	4.55e-04	78	65	4	M39824
Pathway	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	PIK3CB FGFR3 FGFR4 KLB	5.50e-04	82	65	4	M1021
Pathway	REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER	PIK3CB FGFR3 FGFR4 KLB	5.76e-04	83	65	4	M27163
Pubmed	Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.	FASN FGFR3 FGFR4 KLB	1.19e-07	19	84	4	37541847
Pubmed	betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.	FGFR3 FGFR4 KLB	7.54e-07	8	84	3	18187602
Pubmed	Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.	FGFR3 FGFR4 KLB	7.54e-07	8	84	3	17623664
Pubmed	ARIX and PHOX2B polymorphisms in patients with congenital superior oblique muscle palsy.	PHOX2A PHOX2B	5.76e-06	2	84	2	16049556
Pubmed	Effect of increased bile acid synthesis or fecal excretion in irritable bowel syndrome-diarrhea.	FGFR4 KLB	5.76e-06	2	84	2	25070056
Pubmed	Transcriptional regulation of TLX2 and impaired intestinal innervation: possible role of the PHOX2A and PHOX2B genes.	PHOX2A PHOX2B	5.76e-06	2	84	2	17505528
Pubmed	PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma.	PHOX2A PHOX2B	5.76e-06	2	84	2	18949361
Pubmed	PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line.	PHOX2A PHOX2B	5.76e-06	2	84	2	26902400
Pubmed	Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation.	FGFR4 KLB	5.76e-06	2	84	2	20657013
Pubmed	Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.	F2R F2RL2	5.76e-06	2	84	2	23739922
Pubmed	Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma.	FGFR4 KLB	5.76e-06	2	84	2	22439738
Pubmed	Pharmacogenetics of the effects of colesevelam on colonic transit in irritable bowel syndrome with diarrhea.	FGFR4 KLB	5.76e-06	2	84	2	22271411
Pubmed	Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.	F2R F2RL2	5.76e-06	2	84	2	17376866
Pubmed	Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models.	F2R F2RL2	5.76e-06	2	84	2	25261684
Pubmed	FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.	FGFR3 FGFR4	5.76e-06	2	84	2	9716527
Pubmed	Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling.	F2R F2RL2	5.76e-06	2	84	2	20442298
Pubmed	Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.	FGFR3 FGFR4	5.76e-06	2	84	2	20093646
Pubmed	Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province.	FGFR3 FGFR4	5.76e-06	2	84	2	26431494
Pubmed	Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells.	LCTL KLB	5.76e-06	2	84	2	22020932
Pubmed	Altered expressions of fibroblast growth factor receptors and alveolarization in neonatal mice exposed to 85% oxygen.	FGFR3 FGFR4	5.76e-06	2	84	2	17957151
Pubmed	Phenotype-phenotype and genotype-phenotype correlations in patients with idiopathic superior oblique muscle palsy.	PHOX2A PHOX2B	5.76e-06	2	84	2	22170461
Pubmed	The 41-amino-acid C-terminal region of the hepatitis E virus ORF3 protein interacts with bikunin, a kunitz-type serine protease inhibitor.	AMBP SPINT2	5.76e-06	2	84	2	16140784
Pubmed	Specification of the central noradrenergic phenotype by the homeobox gene Phox2b.	PHOX2A PHOX2B	5.76e-06	2	84	2	10736201
Pubmed	Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.	MDGA2 MDGA1	5.76e-06	2	84	2	15019943
Pubmed	Proteinase-activated receptors (PARs)--the PAR3 Neo-N-terminal peptide TFRGAP interacts with PAR1.	F2R F2RL2	5.76e-06	2	84	2	15582715
Pubmed	Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit.	FGFR4 KLB	5.76e-06	2	84	2	24200957
Pubmed	Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients.	F2R F2RL2	5.76e-06	2	84	2	17347481
Pubmed	Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells.	PHOX2A PHOX2B	5.76e-06	2	84	2	19573018
Pubmed	Fgf21 regulates T-cell development in the neonatal and juvenile thymus.	FGFR3 FGFR4 KLB	1.08e-05	18	84	3	28336912
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	EVA1C LCTL CRIM1 FAM3B FAR1 CSGALNACT1 RSPRY1 ACSL5	1.60e-05	460	84	8	20562862
Pubmed	Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways.	F2R F2RL2	1.73e-05	3	84	2	22541814
Pubmed	The cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesion.	FGFR3 FGFR4	1.73e-05	3	84	2	18061161
Pubmed	Liver-specific activities of FGF19 require Klotho beta.	FGFR4 KLB	1.73e-05	3	84	2	17627937
Pubmed	Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin.	F2R F2RL2	1.73e-05	3	84	2	10079109
Pubmed	Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.	FGFR3 FGFR4	1.73e-05	3	84	2	21139072
Pubmed	Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho.	FGFR4 KLB	1.73e-05	3	84	2	21653700
Pubmed	An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene.	PHOX2A PHOX2B	1.73e-05	3	84	2	16127999
Pubmed	Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.	IKZF1 GPR132	1.73e-05	3	84	2	27588474
Pubmed	Dysregulation in IGF-1R, FGFR4 and βKlotho signaling in patients with medullary thyroid cancer.	FGFR4 KLB	1.73e-05	3	84	2	31184820
Pubmed	Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein.	F2R F2RL2	1.73e-05	3	84	2	23921961
Pubmed	Thrombin receptors and protease-activated receptor-2 in human placentation: receptor activation mediates extravillous trophoblast invasion in vitro.	F2R F2RL2	1.73e-05	3	84	2	14507634
Pubmed	Locus coeruleus neurons originate in alar rhombomere 1 and migrate into the basal plate: Studies in chick and mouse embryos.	PHOX2A PHOX2B	1.73e-05	3	84	2	16628617
Pubmed	Phox2 and dHAND transcription factors select shared and unique target genes in the noradrenergic cell type.	PHOX2A PHOX2B	1.73e-05	3	84	2	16280598
Pubmed	Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4.	FGFR3 FGFR4	1.73e-05	3	84	2	21561999
Pubmed	Protease activated receptor-2 mediates activated protein C-induced cutaneous wound healing via inhibition of p38.	F2R F2RL2	1.73e-05	3	84	2	21907694
Pubmed	Platelet specific promoters are insufficient to express protease activated receptor 1 (PAR1) transgene in mouse platelets.	F2R F2RL2	1.73e-05	3	84	2	24830314
Pubmed	Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells.	F2R F2RL2	1.73e-05	3	84	2	12805069
Pubmed	Clinical features, ARIX and PHOX2B nucleotide changes in three families with congenital superior oblique muscle palsy.	PHOX2A PHOX2B	1.73e-05	3	84	2	18323871
Pubmed	Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension.	FGFR3 FGFR4	1.73e-05	3	84	2	8083748
Pubmed	Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cells.	F2R F2RL2	1.73e-05	3	84	2	26729042
Pubmed	Alteration in the serum concentrations of FGF19, FGFR4 and βKlotho in patients with thyroid cancer.	FGFR4 KLB	1.73e-05	3	84	2	29438906
Pubmed	FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development.	FGFR3 FGFR4 KLB	3.01e-05	25	84	3	18625063
Pubmed	Expression of protease-activated receptor-1, -2, -3, and -4 in control and experimentally inflamed mouse bladder.	F2R F2RL2	3.45e-05	4	84	2	12598324
Pubmed	Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.	AMBP SPINT2	3.45e-05	4	84	2	25301953
Pubmed	Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells.	TIE1 SVEP1	3.45e-05	4	84	2	37338522
Pubmed	Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation.	F2R F2RL2	3.45e-05	4	84	2	18412955
Pubmed	Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.	FGFR3 FGFR4	3.45e-05	4	84	2	9664689
Pubmed	Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.	F2R F2RL2	3.45e-05	4	84	2	23647384
Pubmed	BetaKlotho is required for metabolic activity of fibroblast growth factor 21.	FGFR4 KLB	3.45e-05	4	84	2	17452648
Pubmed	Gene and locus structure and chromosomal localization of the protease-activated receptor gene family.	F2R F2RL2	3.45e-05	4	84	2	9722561
Pubmed	Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets.	F2R F2RL2	3.45e-05	4	84	2	10477691
Pubmed	Cathepsin B and its interacting proteins, bikunin and TSRC1, correlate with TNF-induced apoptosis of ovarian cancer cells OV-90.	AMBP SPINT2	3.45e-05	4	84	2	16364318
Pubmed	Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity.	F2R F2RL2	3.45e-05	4	84	2	18347074
Pubmed	Plasticity-related serine proteases in the brain (review).	F2R F2RL2	3.45e-05	4	84	2	10085414
Pubmed	Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.	FGFR3 FGFR4	3.45e-05	4	84	2	9212826
Pubmed	Fibroblast growth factor 21 ameliorates cholestatic liver injury via a hepatic FGFR4-JNK pathway.	FGFR4 ABCB4	3.45e-05	4	84	2	37696161
Pubmed	Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.	FGFR3 FGFR4	3.45e-05	4	84	2	27154171
Pubmed	Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.	FGFR3 FGFR4	3.45e-05	4	84	2	23393200
Pubmed	The roles of proteinase-activated receptors in the vascular physiology and pathophysiology.	F2R F2RL2	3.45e-05	4	84	2	17095716
Pubmed	Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.	FGFR3 FGFR4	3.45e-05	4	84	2	12373339
Pubmed	FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.	FGFR3 FGFR4	3.45e-05	4	84	2	36142417
Pubmed	Human cytomegalovirus increases HUVEC sensitivity to thrombin and modulates expression of thrombin receptors.	F2R F2RL2	3.45e-05	4	84	2	20155436
Pubmed	The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family.	F2R F2RL2	3.45e-05	4	84	2	1851174
Pubmed	Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.	FGFR3 FGFR4	3.45e-05	4	84	2	11759058
Pubmed	The FGF system has a key role in regulating vascular integrity.	FGFR3 FGFR4	3.45e-05	4	84	2	18776942
Pubmed	Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3.	F2R F2RL2	3.45e-05	4	84	2	14980205
Pubmed	RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.	FGFR3 FGFR4	3.45e-05	4	84	2	17304337
Pubmed	Expression of basic fibroblast growth factor and its receptors in human ovarian follicles from adults and fetuses.	FGFR3 FGFR4	3.45e-05	4	84	2	16210019
Pubmed	Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.	FGFR3 FGFR4	3.45e-05	4	84	2	12644244
Pubmed	FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.	FGFR3 FGFR4 KLB	4.75e-05	29	84	3	21876757
Pubmed	The protein tyrosine kinase family of the human genome.	TIE1 ROS1 FGFR3 FGFR4	5.03e-05	83	84	4	11114734
Pubmed	Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.	FGFR3 FGFR4	5.74e-05	5	84	2	27206683
Pubmed	Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.	FGFR3 FGFR4	5.74e-05	5	84	2	15987787
Pubmed	Forced expression of Phox2 homeodomain transcription factors induces a branchio-visceromotor axonal phenotype.	PHOX2A PHOX2B	5.74e-05	5	84	2	17208219
Pubmed	The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.	FGFR3 FGFR4	5.74e-05	5	84	2	27078042
Pubmed	Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.	FGFR3 FGFR4	5.74e-05	5	84	2	16091423
Pubmed	Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development.	MDGA2 MDGA1	5.74e-05	5	84	2	23358245
Pubmed	FGF-dependent regulation of VEGF receptor 2 expression in mice.	FGFR3 FGFR4	5.74e-05	5	84	2	21633168
Pubmed	Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.	F2R F2RL2	5.74e-05	5	84	2	30271984
Pubmed	FGF21 signalling pathway and metabolic traits - genetic association analysis.	FGFR3 KLB	5.74e-05	5	84	2	20717167
Pubmed	Molecular analysis of congenital central hypoventilation syndrome.	PHOX2A PHOX2B	5.74e-05	5	84	2	14566559
Pubmed	Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.	FGFR3 FGFR4	5.74e-05	5	84	2	9771645
Pubmed	FGF receptors control alveolar elastogenesis.	FGFR3 FGFR4	5.74e-05	5	84	2	29122839
Pubmed	Cell-based receptor discovery identifies host factors specifically targeted by the SARS CoV-2 spike.	IL1RAPL2 CNTN1	5.74e-05	5	84	2	35931765
Pubmed	Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization.	F2R F2RL2	5.74e-05	5	84	2	15457341
Pubmed	Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.	FGFR3 FGFR4	5.74e-05	5	84	2	28094278
Pubmed	Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b.	PHOX2A PHOX2B	5.74e-05	5	84	2	14627646
Pubmed	Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.	FGFR4 KLB	5.74e-05	5	84	2	22442730
Pubmed	Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.	FGFR3 FGFR4	5.74e-05	5	84	2	9013630
Pubmed	The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.	FGFR3 FGFR4	5.74e-05	5	84	2	11566361
Interaction	KL interactions	LCTL FGFR3 FGFR4 KLB	2.47e-07	14	82	4	int:KL
Interaction	FBXO2 interactions	NPC1 ATRN CTSF TENM3 ADAMTS7 ACP2 FGFR3 FGFR4 PLXNB2 GNS CNTN1	8.48e-07	411	82	11	int:FBXO2
Interaction	CST11 interactions	ATRN TMEM67 ZBTB20 ADAMTS7 PLXNB2	1.36e-05	75	82	5	int:CST11
Interaction	KLB interactions	FGFR3 FGFR4 KLB	1.39e-05	12	82	3	int:KLB
Interaction	DEFB135 interactions	ATRN TMEM67 CTSF PLXNB2	2.53e-05	42	82	4	int:DEFB135
Interaction	LY86 interactions	ATRN TMEM67 CTSF ADAMTS7 FGFR3 FGFR4 PLXNB2	2.92e-05	217	82	7	int:LY86
Interaction	ELSPBP1 interactions	ATRN TMEM67 ADAMTS7 FGFR3 FGFR4	3.67e-05	92	82	5	int:ELSPBP1
Interaction	PATE1 interactions	ATRN TMEM67 CTSF PLXNB2	4.69e-05	49	82	4	int:PATE1
Interaction	SDF2L1 interactions	NPC1 ATRN TMEM67 ADAMTS7 ROS1 FGFR3 FGFR4 PLXNB2	4.97e-05	322	82	8	int:SDF2L1
Interaction	EDN3 interactions	ATRN ADAMTS7 FGFR3 FGFR4 RSPRY1	7.92e-05	108	82	5	int:EDN3
Interaction	LYPD1 interactions	ATRN ADAMTS7 MYO19 FGFR4	9.14e-05	58	82	4	int:LYPD1
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	TIE1 ROS1 FGFR3 FGFR4	1.51e-05	40	68	4	321
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	WFIKKN2 MDGA2 FGFR3 FGFR4 MDGA1 CNTN1	3.15e-05	161	68	6	593
GeneFamily	F2R receptors	F2R F2RL2	8.32e-05	4	68	2	219
GeneFamily	Immunoglobulin like domain containing	TIE1 IL1RAPL2 MDGA2 MDGA1 CNTN1	7.96e-04	193	68	5	594
GeneFamily	Pseudoautosomal region 1\|Solute carriers	P2RY8 IL3RA	3.95e-03	25	68	2	715
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A11 OTOGL CNGB3 MDGA2 ROS1 HYDIN	3.34e-07	145	84	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A11 TENM3 OTOGL CNGB3 FGFR3 CSGALNACT1	4.76e-07	154	84	6	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A11 OTOGL BAAT MDGA2 ROS1 HYDIN	6.40e-07	162	84	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Children_(3_yrs)-Immune-B_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 CSGALNACT1 ABCB4	1.18e-06	180	84	6	40a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXHD1 OTOGL MDGA2 ROS1 HYDIN CNTN1	1.35e-06	184	84	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXHD1 OTOGL MDGA2 ROS1 HYDIN CNTN1	1.35e-06	184	84	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXHD1 OTOGL MDGA2 ROS1 HYDIN CNTN1	1.35e-06	184	84	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 FGFR3 CUBN GNS ACSL5	1.83e-06	194	84	6	fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	CRIM1 OTOGL MDGA1 PLXNB2 CNTN1 TBX5	2.18e-06	200	84	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 CRIM1 FGFR3 FGFR4 CNTN1	1.31e-05	160	84	5	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 CRIM1 FGFR3 FGFR4 CNTN1	1.31e-05	160	84	5	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 CRIM1 TIE1 IL1RAPL2 CSGALNACT1	1.66e-05	168	84	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 CRIM1 TIE1 IL1RAPL2 CSGALNACT1	1.66e-05	168	84	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL CNGB3 CUBN DNAH6 HYDIN	1.71e-05	169	84	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	1.81e-05	171	84	5	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ATRN EVA1C SLC6A11 FAM3B KLB	2.08e-05	176	84	5	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	Control-B_cells-B_cells\|Control / group, cell type (main and fine annotations)	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.08e-05	176	84	5	d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell	COVID-19-lung-B_cells\|lung / Disease (COVID-19 only), tissue and cell type	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.14e-05	177	84	5	f54691e5558091c1734ab15153a10bff15ed171e
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	CRIM1 FGFR4 SVEP1 CNTN1 TBX5	2.14e-05	177	84	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.14e-05	177	84	5	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CRIM1 FGFR4 SVEP1 CNTN1 TBX5	2.14e-05	177	84	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PHOX2A TENM3 IL1RAPL2 OTOGL WFIKKN2	2.20e-05	178	84	5	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|343B / Donor, Lineage, Cell class and subclass (all cells)	CCNH CTSF PTPN9 MYO19 GPR132	2.20e-05	178	84	5	5289ac61637224ae70ffbc2d164d73116f10af40
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SLC6A11 PHOX2A OR5AU1 MDGA2 PHOX2B	2.20e-05	178	84	5	38ffbd01230c99f52274424ee6c172381daffc73
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PHOX2A TENM3 IL1RAPL2 OTOGL WFIKKN2	2.20e-05	178	84	5	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.38e-05	181	84	5	57f20341c3e9f9f6ed5b6c181605ad35bae91414
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM3 ADAMTS7 WFIKKN2 PHOX2B CNTN1	2.38e-05	181	84	5	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM3 ADAMTS7 WFIKKN2 PHOX2B CNTN1	2.38e-05	181	84	5	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM67 TENM3 MDGA2 PHOX2B ABCB4	2.38e-05	181	84	5	a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM3 ADAMTS7 WFIKKN2 PHOX2B CNTN1	2.38e-05	181	84	5	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE EVA1C CRIM1 TIE1 FGFR3	2.51e-05	183	84	5	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGD SLC15A1 CUBN PLEKHA7 HYDIN	2.51e-05	183	84	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.57e-05	184	84	5	f4c9272d5cc4a70df051413b5c60ca6d1d80eb84
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE EVA1C PLEKHA7 DNAH6 HYDIN	2.57e-05	184	84	5	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE EVA1C PLEKHA7 DNAH6 HYDIN	2.57e-05	184	84	5	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE EVA1C PLEKHA7 DNAH6 HYDIN	2.57e-05	184	84	5	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CRIM1 MDGA2 MDGA1 CNTN1 TBX5	2.57e-05	184	84	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	Children_(3_yrs)-Immune-B_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.71e-05	186	84	5	aa576748921a318798b911a611f05319b95e8d5e
ToppCell	Immune-B_cell\|World / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	2.78e-05	187	84	5	795690c6306c366e733279491138d0cd9b469b21
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SELE TIE1 F2RL2 IL3RA CSGALNACT1	2.85e-05	188	84	5	b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCell	background-B_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	P2RY8 IKZF1 WDFY4 IL3RA CSGALNACT1	2.85e-05	188	84	5	9acb7a95e3095f15918a5d094107d1d565a42842
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFR4 DNAH6 IL3RA SVEP1 TBX5	2.93e-05	189	84	5	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFR4 DNAH6 IL3RA SVEP1 TBX5	2.93e-05	189	84	5	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFR4 DNAH6 IL3RA SVEP1 TBX5	2.93e-05	189	84	5	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 TIE1 ST6GAL1 F2R CSGALNACT1	2.93e-05	189	84	5	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 TIE1 ST6GAL1 F2R CSGALNACT1	3.00e-05	190	84	5	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SELE EVA1C CRIM1 TIE1 ST6GAL1	3.00e-05	190	84	5	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	3.00e-05	190	84	5	424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCell	Fetal_29-31_weeks-Immune-B_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	3.08e-05	191	84	5	84452125d1b5b76974e3f9126f611eff16d45c25
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C SPINT2 ST6GAL1 F2R CSGALNACT1	3.08e-05	191	84	5	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CRIM1 CUBN F2R IL3RA CSGALNACT1	3.08e-05	191	84	5	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	background-B_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	AMBP P2RY8 IKZF1 WDFY4 CSGALNACT1	3.08e-05	191	84	5	a189fdc9c739bb0801e2f38af0932a1ea615cb34
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CRIM1 CUBN F2R IL3RA CSGALNACT1	3.08e-05	191	84	5	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	15-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	SELE TIE1 ADAMTS7 F2R IL3RA	3.23e-05	193	84	5	6ea0444fc3dc156997129387184e6418947f4b12
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 ST6GAL1 FGFR3 CUBN	3.23e-05	193	84	5	32eb026d4317c1499d51294d396dfd5f293f9deb
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 ST6GAL1 FGFR3 CUBN	3.23e-05	193	84	5	930df79b0600f43617052313294be33bcf5631f0
ToppCell	15-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	SELE TIE1 ADAMTS7 F2R IL3RA	3.23e-05	193	84	5	b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE EVA1C TIE1 IL3RA CSGALNACT1	3.23e-05	193	84	5	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE EVA1C TIE1 ST6GAL1 F2R	3.23e-05	193	84	5	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM3B IL3RA CSGALNACT1 GNS ABCB4	3.32e-05	194	84	5	b829a63b51b92507a53ffd0393bd9458b2b9440f
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 CRIM1 FGFR4 F2R SVEP1	3.32e-05	194	84	5	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPINT2 CRIM1 FGFR4 F2R SVEP1	3.32e-05	194	84	5	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE EVA1C CRIM1 TIE1 CSGALNACT1	3.40e-05	195	84	5	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	Endothelial\|World / shred by cell class for bronchial biopsy	SELE CRIM1 TIE1 IL3RA CSGALNACT1	3.40e-05	195	84	5	f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELE EVA1C TIE1 P2RY8 ST6GAL1	3.48e-05	196	84	5	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	3'-Child09-12\|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC15A1 IKZF1 FAM3B CUBN ACSL5	3.48e-05	196	84	5	1bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 ATRN SLC6A11 FASN FGFR3	3.48e-05	196	84	5	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELE EVA1C TIE1 P2RY8 ST6GAL1	3.48e-05	196	84	5	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELE EVA1C TIE1 P2RY8 ST6GAL1	3.48e-05	196	84	5	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P2RY8 ST6GAL1 IKZF1 WDFY4 ABCB4	3.48e-05	196	84	5	de43dd0697e1daf4d50800957cf0b27b54a7a333
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SELE EVA1C CRIM1 TIE1 F2RL2	3.57e-05	197	84	5	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	390C-Endothelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE EVA1C CRIM1 TIE1 IL3RA	3.57e-05	197	84	5	aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE EVA1C CRIM1 TIE1 IL3RA	3.57e-05	197	84	5	7a1a3839b2c965136663241b0d4e96c64cfb656a
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	PHOX2A SPINT2 CRIM1 FGFR4 SVEP1	3.57e-05	197	84	5	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 ATRN SLC6A11 FASN FGFR3	3.65e-05	198	84	5	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE EVA1C CRIM1 TIE1 IL3RA	3.65e-05	198	84	5	f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE EVA1C CRIM1 TIE1 IL3RA	3.65e-05	198	84	5	5b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE EVA1C CRIM1 TIE1 IL3RA	3.65e-05	198	84	5	13203249e5743ba2699871c184d141207e550a86
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SELE CRIM1 TIE1 F2R CSGALNACT1	3.65e-05	198	84	5	56b746e5791b47fe33a7872f0942ae0747b13d4a
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SELE CRIM1 TIE1 F2R CSGALNACT1	3.65e-05	198	84	5	531b0f88c95f813e3914c96749f591e80ca321d0
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE EVA1C CRIM1 TIE1 IL3RA	3.65e-05	198	84	5	5b5ccce5de82ea041465e656147cec3b8beb865b
ToppCell	3'-Child09-12-SmallIntestine-Epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 FAM3B CUBN ACSL5	3.74e-05	199	84	5	043c65bdf54a1bf0e483fea9ffc042ff5b271764
ToppCell	3'-Child04-06-SmallIntestine-Epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 FAM3B CUBN ACSL5	3.74e-05	199	84	5	ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IKZF1 DNAH6 WDFY4 IL3RA GPR132	3.74e-05	199	84	5	7271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPINT2 SLC15A1 CUBN GNS ACSL5	3.74e-05	199	84	5	f26c20f5d7470e90eaa79613d0b87bd4865585a8
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P2RY8 IKZF1 WDFY4 GPR132 ABCB4	3.83e-05	200	84	5	4f7be296be0cd54cfc62cc93263fde26210c61f4
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SELE TIE1 CNGB3 DNAH6	1.11e-04	131	84	4	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGD BAAT UHRF1 WDFY4	1.68e-04	146	84	4	74009a2921359a8352afbaea8c325a3743622543
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGD BAAT UHRF1 WDFY4	1.68e-04	146	84	4	cb19f2bb6832d11fe69b670df49eac096a378a9d
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UHRF1 IKZF1 WDFY4 IL3RA	1.86e-04	150	84	4	57f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CABYR PIK3CB MDGA1 THAP12	1.96e-04	152	84	4	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	3'_v3-Lung-Lymphocytic_B-Naive_B_cells\|Lung / Manually curated celltypes from each tissue	IGHV3-13 CNGB3 ST6GAL1 ABCB4	2.06e-04	154	84	4	2b7d7f09c75bbc22de1358fc44b8ad5d3f656617
ToppCell	343B-Myeloid-Dendritic-cDC1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	P2RY8 WDFY4 KLB FARP2	2.06e-04	154	84	4	71d33b5dbfab5820e3daddb01806a69116ba8008
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HOXC11 P2RY8 ST6GAL1 F2RL2	2.16e-04	156	84	4	ea9223bb6450b22df11efa1705ab72dab005244a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HOXC11 P2RY8 ST6GAL1 F2RL2	2.16e-04	156	84	4	586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DIO3 IRF2BPL F2R CSGALNACT1	2.22e-04	157	84	4	1e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCell	severe_influenza-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	CABYR P2RY8 IKZF1 FGFR4	2.27e-04	158	84	4	8ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAU2 UHRF1 F2RL2 CNTN1	2.33e-04	159	84	4	95128a2367ff2a639b21913c0350924c174faef8
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CABYR MYO19 CSTF1 CSGALNACT1	2.33e-04	159	84	4	08a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CABYR MYO19 CSTF1 CSGALNACT1	2.33e-04	159	84	4	9bdfa7f5aa7753fe25b787bd43d694b6093d77eb
Computational	Genes in the cancer module 85.	TIE1 ROS1 FGFR3 FGFR4 IL3RA	2.33e-06	51	46	5	MODULE_85
Computational	Genes in the cancer module 199.	TIE1 ROS1 FGFR3 FGFR4 IL3RA	4.07e-06	57	46	5	MODULE_199
Computational	Genes in the cancer module 55.	SELE AMBP HGD SLC6A11 ZBTB20 CRIM1 BAAT ST6GAL1 FGFR3 FGFR4 IL3RA TBX5	1.42e-04	832	46	12	MODULE_55
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	NPC1 ATRN CRIM1 FGFR3 FGFR4 PLXNB2 GNS	1.89e-06	161	82	7	3556_DN
Disease	high grade glioma (implicated_via_orthology)	PIK3CB ST6GAL1 FGFR3 FGFR4	6.91e-06	44	82	4	DOID:3070 (implicated_via_orthology)
Disease	Polydactyly	TTC8 TMEM67 SPINT2 FGFR3 TBX5	1.92e-05	117	82	5	C0152427
Disease	bone disease (implicated_via_orthology)	FGFR3 FGFR4	7.59e-05	5	82	2	DOID:0080001 (implicated_via_orthology)
Disease	IgG disialylation measurement	ST6GAL1 IKZF1	7.59e-05	5	82	2	EFO_0008429
Disease	Liver Cirrhosis	NPC1 TMEM67 F2R ABCB4	1.99e-04	103	82	4	C0023890
Disease	kidney disease (implicated_via_orthology)	LCTL CUBN KLB	2.04e-04	41	82	3	DOID:557 (implicated_via_orthology)
Disease	IgG digalactosylation measurement	ST6GAL1 IKZF1	2.11e-04	8	82	2	EFO_0008424
Disease	Fibrosis, Liver	NPC1 TMEM67 F2R ABCB4	2.14e-04	105	82	4	C0239946
Disease	IgG bisecting N-acetyl glucosamine measurement	ST6GAL1 IKZF1	2.71e-04	9	82	2	EFO_0008426
Disease	IgG monogalactosylation measurement	ST6GAL1 IKZF1	2.71e-04	9	82	2	EFO_0008423
Disease	IgG sialylation measurement	ST6GAL1 IKZF1	3.38e-04	10	82	2	EFO_0008428
Disease	pulse pressure measurement	NPC1 EVA1C TTC8 FASN CRIM1 UHRF1 PLXNB2 PLEKHA7 HYDIN SVEP1 KLB TBX5	4.51e-04	1392	82	12	EFO_0005763
Disease	IgG galactosylation measurement	ST6GAL1 IKZF1	4.94e-04	12	82	2	EFO_0008425
Disease	microphthalmia (implicated_via_orthology)	CRIM1 STAU2	4.94e-04	12	82	2	DOID:10629 (implicated_via_orthology)
Disease	Bardet-Biedl syndrome (is_implicated_in)	TTC8 TMEM67	6.79e-04	14	82	2	DOID:1935 (is_implicated_in)
Disease	Proteinuria	ADAMTS7 CUBN	7.82e-04	15	82	2	HP_0000093
Disease	focal segmental glomerulosclerosis	FGFR4 DNAH6	8.93e-04	16	82	2	EFO_0004236
Disease	Bardet-Biedl syndrome	TTC8 TMEM67	1.13e-03	18	82	2	cv:C0752166
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 HYDIN	1.27e-03	19	82	2	DOID:10908 (implicated_via_orthology)
Disease	response to antidepressant	WFIKKN2 MDGA1 CSGALNACT1 CNTN1	1.49e-03	176	82	4	GO_0036276
Disease	tissue factor measurement	AMBP CNTN1	1.55e-03	21	82	2	EFO_0010623
Disease	N-glycan measurement	ST6GAL1 IKZF1	1.70e-03	22	82	2	EFO_0004999
Disease	Adenocarcinoma of lung (disorder)	FASN ROS1 FGFR3 FGFR4	2.64e-03	206	82	4	C0152013
Disease	oral squamous cell carcinoma (is_implicated_in)	FGFR3 FGFR4	2.75e-03	28	82	2	DOID:0050866 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RYFYNGTSMACETFQ	AMBP	246	P02760
GDMFYSQAHYRANEF	BAAT	41	Q14032
GTACMYFKRFYLNNS	CCNH	81	P51946
YRCMQSQFSVLYNES	RNF20	381	Q5VTR2
FGFGMTCQYRSDFIN	CSGALNACT1	421	Q8TDX6
SCAYQVARGMQYLES	FGFR4	591	P22455
FAAAYFQELTMYRGN	CABYR	36	O75952
LQYGAYSAFCEDMDN	ADAMTS7	476	Q9UKP4
FIYDMCGSNYANFEL	PTPN9	151	P43378
CNVVTVAFYANMYSS	P2RY8	96	Q86VZ1
RDMSGTYRCQTARYN	MDGA1	506	Q8NFP4
EVFMHVSTAYAYCNR	FAR1	146	Q8WVX9
QARYMADTFYTNAGC	MYO19	56	Q96H55
MANSSSSAYGAYFER	DIO3	246	P55073
YNLTGFNITYSFDMC	ATRN	236	O75882
MNSLRAGDTAVYYCA	IGHV3-13	101	P01766
TEMEYGNVYFFNCDC	LOXHD1	1901	Q8IVV2
DASYMAAVNSTGNCY	MLST8	181	Q9BVC4
YSSASGVAKQMYQDC	IRF2BPL	431	Q9H1B7
TSYQYPFYDCRQAMS	PLXNB2	606	O15031
NVSMANYFRDYANLC	LCTL	171	Q6UWM7
SYNACAAQMYIFVAF	OR5B3	91	Q8NH48
GSFGNCSSQYEEYRM	NAA16	811	Q6N069
MTYDEASAYCQQRYT	SELE	31	P16581
ECNMCGYHSQDRYEF	IKZF1	491	Q13422
YVTGNVTATRCFDMY	FAM3B	116	P58499
GMYRCQTSQYNGFNV	MDGA2	511	Q7Z553
FSISQAFMYFSYAGC	ABCB4	941	P21439
NMEYCRGQAYIVSSG	THAP12	321	O43422
RFVTAAFYCNMYASI	F2R	176	P25116
CRATTVIFYGNMYCS	F2RL2	166	O00254
YYVGQSFANAMYNAC	NPC1	146	O15118
YQEDSGNFSVEMYFR	ACP2	316	P11117
MSFTYQIADCNRDYH	CUBN	3386	O60494
QSAFYGQDYQMCSSQ	EVA1C	86	P58658
DNCVARMALSQYTYG	DNAH6	1421	Q9C0G6
ADYSMPAVNNSYCQF	IL3RA	56	P26951
TSYNFGTCFIYQAGM	HYDIN	4316	Q4G0P3
IYYCLASNNYGMVRS	CNTN1	111	Q12860
DYSYQGHMQSCNFSA	CTSF	356	Q9UBX1
CVFNNVEYYDGDMFR	CRIM1	336	Q9NZV1
FRAAMGCQVYEAYGQ	ACSL5	431	Q9ULC5
RNSYSSCYAAADELM	HOXC11	86	O43248
DAYNNTYACVRTMSA	GNS	446	P15586
AAFIAYAGYFDQQMR	DYNC1H1	3511	Q14204
DIFNDYATYCFQMFG	KLB	216	Q86Z14
SCAYQVARGMEYLAS	FGFR3	596	P22607
CSVNYNSSANMYVTG	CSTF1	266	Q05048
ECDYFGMEFQNTQSY	FARP2	81	O94887
GYSYGACVAFEMCSQ	FASN	2306	P49327
VNEFCERFSYYGMRA	SLC15A1	21	P46059
IQSAFDEAMSYCRYH	MED6	126	O75586
TFDGNNAALYSMASY	OTOGL	1546	Q3ZCN5
SMENRCFYNSDGDFL	HGD	141	Q93099
NMNSYDFATFDACGL	TMEM67	256	Q5HYA8
AAAFSYYRGDRNAMC	GPR132	266	Q9UNW8
GFFAAASFMSYQQCE	RSPRY1	461	Q96DX4
ASYRTESAQRQACMY	TBX5	366	Q99593
SGFYTCVLRNSTYCM	IL1RAPL2	111	Q9NP60
QMFFYAGFATSECYL	OR5AU1	151	Q8NGC0
QAEQSGMRTYYFSAD	PLEKHA7	251	Q6IQ23
YQKFFDSACTMGAYH	ST6GAL1	356	P15907
YDVMGQYDATFNCST	SHISA7	86	A6NL88
DSYMFACVNQTAVYE	PIK3CB	76	P42338
NYSFGAMVAYSCNKG	SVEP1	2161	Q4LDE5
MAQLEGYYFSAALSC	ALG10	1	Q5BKT4
GAATANQNYFRACMD	CNGB3	446	Q9NQW8
CFYAQQYDMTLTSFE	TTC8	396	Q8TAM2
ANYNFRGMYNQRYHC	STAU2	126	Q9NUL3
DSQLGDAAMYFCAYR	TRA	101	P0DTU3
DAAMYFCAYRSAVNA	TRA	106	P0DTU3
AYVNMSLFENFTYAG	TIE1	1116	P35590
MFNYEEYCTANAVTG	SPINT2	126	O43291
MDYSYLNSYDSCVAA	PHOX2A	1	O14813
EYLMYLNTAAGRTCN	WDFY4	2551	Q6ZS81
LNTAAGRTCNDYMQY	WDFY4	2556	Q6ZS81
YIFQLFDSYAASGMC	SLC6A11	461	P48066
GMVNARFDYSYDNSF	TENM3	2011	Q9P273
AVCYTADNEMGYYAE	ROS1	1186	P08922
DRIYSALYACSMQNG	ZBTB20	241	Q9HC78
TGYFSICDRYMNGTC	ZC3H7A	901	Q8IWR0
ACRYDLGRSYAMQVN	UHRF1	761	Q96T88
DSQLGDAAMYFCAYR	TRAV38-2DV8	101	A0JD32
YSYLNSSAYESCMAG	PHOX2B	6	Q99453
SRQMDYLGTFFSYCS	ZFYVE26	1146	Q68DK2
CASDGLTYYNRCYMD	WFIKKN2	146	Q8TEU8