Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

HGF KLK7 PRSS12 RBP3 TYSND1 PRSS36 PRSS3P2 CD5L

4.08e-052071228GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

HGF KLK7 PRSS12 RBP3 TYSND1 PRSS36 PRSS3P2 CD5L

4.83e-052121228GO:0017171
GeneOntologyMolecularFunctionserine-type endopeptidase activity

HGF KLK7 PRSS12 TYSND1 PRSS36 PRSS3P2 CD5L

1.69e-041901227GO:0004252
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TRIO NTRK3 DGKE HUNK MAP3K6 CDKL1 FCSK PASK TNNI3K AATK CSF1R GUCY2D PIP5KL1

4.01e-0470912213GO:0016773
GeneOntologyBiologicalProcessnegative regulation of complement activation, classical pathway

CR1 CR2 SVEP1

1.08e-0581213GO:0045959
GeneOntologyBiologicalProcessregulation of complement activation

CR1 CR2 SVEP1 CD5L

1.78e-05271214GO:0030449
GeneOntologyBiologicalProcessregulation of complement activation, classical pathway

CR1 CR2 SVEP1

2.29e-05101213GO:0030450
GeneOntologyBiologicalProcessregulation of humoral immune response

KLK7 CR1 CR2 SVEP1 CD5L

2.70e-05601215GO:0002920
GeneOntologyBiologicalProcessnegative regulation of humoral immune response mediated by circulating immunoglobulin

CR1 CR2 SVEP1

4.17e-05121213GO:0002924
GeneOntologyBiologicalProcesstube development

HGF FNDC3B GRN ITGA2B STAB1 SRPX2 FBN1 CSF1R OTULIN PKD1 UMOD ASB2 MYO18B CSMD1 IL1A PDGFC PERCC1 EP300 NOTCH3 SMAD6 PCNT

6.24e-05140212121GO:0035295
GeneOntologyBiologicalProcessnegative regulation of complement activation

CR1 CR2 SVEP1

6.84e-05141213GO:0045916
GeneOntologyBiologicalProcessnegative regulation of B cell mediated immunity

CR1 CR2 SVEP1

1.04e-04161213GO:0002713
GeneOntologyBiologicalProcessnegative regulation of immunoglobulin mediated immune response

CR1 CR2 SVEP1

1.04e-04161213GO:0002890
GeneOntologyBiologicalProcesspositive regulation of neuron projection regeneration

HGF NTRK3 GRN

1.51e-04181213GO:0070572
GeneOntologyBiologicalProcessnegative regulation of humoral immune response

CR1 CR2 SVEP1

1.78e-04191213GO:0002921
GeneOntologyCellularComponentcell surface

MYO18A ITGA2B CR1 CR2 PLA2R1 SRPX2 CD5L ARSB CSF1R UMODL1 PKD1 UMOD SCART1 IL1A PDGFC IL3RA NOTCH3 TREML2

6.31e-05111112018GO:0009986
MousePhenomitral valve regurgitation

FBN1 ARSB PCNT

1.01e-057943MP:0006045
MousePhenoabnormal heart atrium and ventricle connection

NTRK3 FBN1 ARSB SETD5 PKD1 SMAD6

1.09e-0575946MP:0010435
MousePhenoheart valve hyperplasia

NTRK3 ARSB SMAD6

2.40e-059943MP:0003958
MousePhenoeffusion

KMT2B MUC5B FBN1 SETD5 PKD1 MYO18B EP300

7.26e-05152947MP:0021205
MousePhenoatrioventricular valve regurgitation

FBN1 ARSB PCNT

8.02e-0513943MP:0006046
MousePhenoabnormal atrioventricular valve morphology

NTRK3 FBN1 ARSB PKD1 SMAD6

9.88e-0569945MP:0002745
MousePhenopericardial effusion

KMT2B FBN1 SETD5 PKD1 MYO18B EP300

1.01e-04111946MP:0005312
MousePhenoabnormal heart valve morphology

NTRK3 FBN1 ARSB SETD5 PKD1 EP300 SMAD6

1.13e-04163947MP:0000285
MousePhenoabnormal mitral valve morphology

NTRK3 FBN1 ARSB SMAD6

1.60e-0441944MP:0000286
DomainUnchr_dom_Cys-rich

KCP MUC5B TECTA SSPOP FCGBP

1.05e-08131165IPR014853
DomainC8

KCP MUC5B TECTA SSPOP FCGBP

1.05e-08131165SM00832
DomainTIL_dom

KCP MUC5B TECTA SSPOP FCGBP

1.62e-08141165IPR002919
DomainVWF_type-D

KCP MUC5B TECTA SSPOP FCGBP

3.50e-08161165IPR001846
DomainVWFD

KCP MUC5B TECTA SSPOP FCGBP

3.50e-08161165PS51233
DomainVWD

KCP MUC5B TECTA SSPOP FCGBP

3.50e-08161165SM00216
DomainVWD

KCP MUC5B TECTA SSPOP FCGBP

3.50e-08161165PF00094
DomainVWC_out

KCP MUC5B TECTA SSPOP FCGBP

9.19e-08191165SM00215
DomainC8

MUC5B TECTA SSPOP FCGBP

6.73e-07121164PF08742
DomainTIL

MUC5B TECTA SSPOP FCGBP

6.73e-07121164PF01826
DomainEGF

LAMC1 TECTA SVEP1 GPR179 STAB1 FBN1 FCGBP UMODL1 UMOD NOTCH3

2.09e-0623511610SM00181
DomainVWC

KCP MUC5B TECTA SSPOP FCGBP

3.61e-06381165SM00214
DomainGrowth_fac_rcpt_

LAMC1 SVEP1 GPR179 STAB1 FBN1 UMODL1 UMOD NOTCH3

5.86e-061561168IPR009030
DomainVWF_dom

KCP MUC5B TECTA SSPOP FCGBP

6.00e-06421165IPR001007
DomainSushi

CR1 CR2 SVEP1 SRPX2 CSMD1

1.74e-05521165PF00084
DomainCCP

CR1 CR2 SVEP1 SRPX2 CSMD1

2.10e-05541165SM00032
DomainSUSHI

CR1 CR2 SVEP1 SRPX2 CSMD1

2.51e-05561165PS50923
DomainEGF-like_dom

LAMC1 TECTA SVEP1 STAB1 FBN1 FCGBP UMODL1 UMOD NOTCH3

2.54e-052491169IPR000742
DomainSushi_SCR_CCP_dom

CR1 CR2 SVEP1 SRPX2 CSMD1

2.74e-05571165IPR000436
DomainGFP-like

SVEP1 STAB1 UMOD

3.71e-05111163IPR023413
Domain-

SVEP1 STAB1 UMOD

3.71e-051111632.40.155.10
DomainZP_2

TECTA UMODL1 UMOD

8.08e-05141163PS51034
DomainZP_1

TECTA UMODL1 UMOD

8.08e-05141163PS00682
DomainVWFC_2

KCP MUC5B TECTA SSPOP

8.86e-05381164PS50184
DomainZP

TECTA UMODL1 UMOD

1.01e-04151163SM00241
DomainEGF_CA

SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

1.13e-041221166SM00179
DomainHYR

SVEP1 SRPX2

1.14e-0431162PS50825
DomainTILa_dom

TECTA FCGBP

1.14e-0431162IPR025615
DomainHYR_dom

SVEP1 SRPX2

1.14e-0431162IPR003410
DomainTILa

TECTA FCGBP

1.14e-0431162PF12714
DomainHYR

SVEP1 SRPX2

1.14e-0431162PF02494
DomainEGF-like_Ca-bd_dom

SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

1.24e-041241166IPR001881
DomainZP_dom

TECTA UMODL1 UMOD

1.49e-04171163IPR001507
DomainZona_pellucida

TECTA UMODL1 UMOD

1.49e-04171163PF00100
DomainEGF_1

LAMC1 SSPOP SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

1.93e-042551168PS00022
DomainEGF_CA

SVEP1 FBN1 UMODL1 UMOD NOTCH3

1.98e-04861165PF07645
DomainREJ

PKD1L2 PKD1

2.28e-0441162PS51111
DomainREJ_dom

PKD1L2 PKD1

2.28e-0441162IPR014010
DomainEGF_2

LAMC1 SSPOP SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

2.51e-042651168PS01186
DomainEGF_Ca-bd_CS

SVEP1 FBN1 UMODL1 UMOD NOTCH3

3.47e-04971165IPR018097
DomainEGF_CA

SVEP1 FBN1 UMODL1 UMOD NOTCH3

3.81e-04991165PS01187
DomainASX_HYDROXYL

SVEP1 FBN1 UMODL1 UMOD NOTCH3

3.99e-041001165PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SVEP1 FBN1 UMODL1 UMOD NOTCH3

5.21e-041061165IPR000152
DomainKinase-like_dom

TRIO NTRK3 WDR81 HUNK MAP3K6 CDKL1 PASK TNNI3K AATK CSF1R GUCY2D

5.59e-0454211611IPR011009
DomainPKD/REJ-like

PKD1L2 PKD1

5.64e-0461162IPR002859
DomainREJ

PKD1L2 PKD1

5.64e-0461162PF02010
DomainEGF_3

SSPOP SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

6.66e-042351167PS50026
DomainTryp_SPc

HGF KLK7 PRSS12 TYSND1 PRSS36

8.17e-041171165SM00020
DomainProt_kinase_dom

TRIO NTRK3 HUNK MAP3K6 CDKL1 PASK TNNI3K AATK CSF1R GUCY2D

9.46e-0448911610IPR000719
DomainTrypsin_dom

HGF KLK7 PRSS12 TYSND1 PRSS36

9.50e-041211165IPR001254
DomainTrypsin

HGF KLK7 PRSS12 TYSND1 PRSS36

9.50e-041211165PF00089
DomainPROTEIN_KINASE_DOM

TRIO NTRK3 HUNK MAP3K6 CDKL1 PASK TNNI3K AATK CSF1R GUCY2D

1.01e-0349311610PS50011
DomainKringle-like

HGF PRSS12 PLA2R1

1.02e-03321163IPR013806
DomainPeptidase_S1_PA

HGF KLK7 PRSS12 TYSND1 PRSS36

1.02e-031231165IPR009003
DomainEGF

TECTA SVEP1 STAB1 UMOD NOTCH3

1.14e-031261165PF00008
DomainGPS

PKD1L2 PKD1 ADGRD2

1.21e-03341163SM00303
DomainEGF-like_CS

LAMC1 SVEP1 STAB1 FBN1 UMODL1 UMOD NOTCH3

1.23e-032611167IPR013032
DomainPkinase_Tyr

NTRK3 TNNI3K AATK CSF1R GUCY2D

1.26e-031291165PF07714
DomainGPS

PKD1L2 PKD1 ADGRD2

1.32e-03351163PF01825
DomainDUF1220

NBPF4 NBPF6

1.34e-0391162SM01148
DomainVWFC_1

KCP MUC5B SSPOP

1.44e-03361163PS01208
DomainGPS

PKD1L2 PKD1 ADGRD2

1.44e-03361163PS50221
DomainGPS

PKD1L2 PKD1 ADGRD2

1.56e-03371163IPR000203
DomainZP_dom_CS

TECTA UMOD

1.67e-03101162IPR017977
DomainSer-Thr/Tyr_kinase_cat_dom

NTRK3 TNNI3K AATK CSF1R GUCY2D

1.70e-031381165IPR001245
DomainDUF1220

NBPF4 NBPF6

2.03e-03111162PF06758
DomainPentaxin-related

SVEP1 ADGRD2

2.03e-03111162IPR001759
DomainPentaxin

SVEP1 ADGRD2

2.03e-03111162PF00354
DomainPKD_channel

PKD1L2 PKD1

2.03e-03111162PF08016
DomainNBPF_dom

NBPF4 NBPF6

2.03e-03111162IPR010630
DomainNBPF

NBPF4 NBPF6

2.03e-03111162PS51316
DomainPKD1_2_channel

PKD1L2 PKD1

2.03e-03111162IPR013122
DomainPROTEIN_KINASE_ATP

TRIO NTRK3 HUNK MAP3K6 CDKL1 PASK TNNI3K AATK CSF1R

2.27e-034591169PS00107
DomainEGF_dom

STAB1 UMOD

2.42e-03121162IPR024731
DomainEGF_3

STAB1 UMOD

2.42e-03121162PF12947
DomainProtein_kinase_ATP_BS

NTRK3 HUNK MAP3K6 CDKL1 PASK TNNI3K AATK CSF1R

2.53e-033791168IPR017441
Domain-

PKD1L2 STAB1 PLA2R1 PKD1

3.14e-039711643.10.100.10
DomainC-type_lectin-like/link

PKD1L2 STAB1 PLA2R1 PKD1

3.38e-03991164IPR016186
DomainCTDL_fold

PKD1L2 STAB1 PLA2R1 PKD1

4.46e-031071164IPR016187
DomainKringle_CS

HGF PRSS12

4.89e-03171162IPR018056
DomainEMI

SSPOP UMODL1

4.89e-03171162PS51041
DomainKRINGLE_1

HGF PRSS12

4.89e-03171162PS00021
DomainKR

HGF PRSS12

4.89e-03171162SM00130
DomainKringle

HGF PRSS12

4.89e-03171162IPR000001
DomainKRINGLE_2

HGF PRSS12

4.89e-03171162PS50070
DomainKringle

HGF PRSS12

4.89e-03171162PF00051
DomainPeptidase_S1A

HGF KLK7 PRSS12 PRSS36

5.41e-031131164IPR001314
DomainLH2

PKD1L2 PKD1

5.48e-03181162SM00308
DomainCTCK_1

MUC5B SSPOP

5.48e-03181162PS01185
DomainTRYPSIN_DOM

HGF KLK7 PRSS12 PRSS36

5.75e-031151164PS50240
DomainMyosin-like_IQ_dom

MYO18A MYO18B

6.10e-03191162IPR027401
Domain-

MYO18A MYO18B

6.10e-031911624.10.270.10
DomainEGF_extracell

SVEP1 STAB1 NOTCH3

6.18e-03601163IPR013111
DomainEGF_2

SVEP1 STAB1 NOTCH3

6.18e-03601163PF07974
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

ITGA2B CR1 CR2 CSF1R IL1A IL3RA

6.64e-0687756M6856
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

NTRK3 CR1 CR2 PLA2R1 GPR61 NOTCH3

1.92e-06101126623382219
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

GRN STAB1 FBN1 NOTCH3

4.79e-0631126431550482
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

FNDC3B GRN PGLYRP2 CR1 CR2 LMAN1L FCGBP CD5L UMODL1 ICAM5 UMOD IRGC IL1A

9.85e-068241261320237496
Pubmed

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.

NTRK3 ANKS1B PON2

9.97e-0612126316537434
Pubmed

Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.

CR1 CR2

1.30e-052126214635039
Pubmed

Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.

HGF GRN

1.30e-052126227030285
Pubmed

The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.

CR1 CR2

1.30e-052126211981823
Pubmed

Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.

CR1 CR2

1.30e-05212621708808
Pubmed

The subcellular distribution of calnexin is mediated by PACS-2.

CANX PACS2

1.30e-052126218417615
Pubmed

Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.

CSF1R NOTCH3

1.30e-052126229544907
Pubmed

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.

FBN1 NOTCH3

1.30e-052126232616814
Pubmed

Comparative functional evolution of human and mouse CR1 and CR2.

CR1 CR2

1.30e-052126218713965
Pubmed

Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration.

UMODL1 UMOD

1.30e-052126223190605
Pubmed

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.

ADAMTS10 FBN1

1.30e-052126221402694
Pubmed

Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.

CR1 CR2

1.30e-052126237833411
Pubmed

[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].

CR1 CR2

1.30e-052126226189291
Pubmed

Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.

CR1 CR2

1.30e-052126223440418
Pubmed

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

TCERG1L HUNK CR2

3.04e-0517126321490949
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

LAMC1 ITGA2B FBN1

3.64e-0518126339040056
Pubmed

A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.

FBN1 PKD1

3.90e-053126224071006
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

ADAMTS10 FBN1

3.90e-053126230201140
Pubmed

Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell culture model of endotoxemia.

SVEP1 SRPX2

3.90e-053126220236627
Pubmed

Oral lupus erythematosus: Immunohistochemical evaluation of CD1a, CD21, CD123, and langerin expression in dendritic cells.

CR2 IL3RA

3.90e-053126238287771
Pubmed

Hepatocyte growth factor, a determinant of airspace homeostasis in the murine lung.

HGF FBN1

3.90e-053126223459311
Pubmed

PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway.

CANX PON2

3.90e-053126236840500
Pubmed

Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.

CR1 CR2

3.90e-05312627690834
Pubmed

Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751.

HGF ANKS1B

3.90e-053126212837293
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CR1 CR2

3.90e-05312623782802
Pubmed

alphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb in the calnexin cycle via the N15-linked glycan.

CANX ITGA2B

3.90e-053126216304048
Pubmed

Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.

CR1 CR2

3.90e-05312622528587
Pubmed

Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.

CR1 CR2

3.90e-05312627528766
Pubmed

HGF/c-Met signalling promotes Notch3 activation and human vascular smooth muscle cell osteogenic differentiation in vitro.

HGF NOTCH3

3.90e-053126221920521
Pubmed

The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.

CR1 CR2

3.90e-05312622139460
Pubmed

EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia.

IL3RA EP300

3.90e-053126238566191
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

DBF4B LAMC1 GRN TACC2 CORO1B STAB1 FBN1 CEP72 MAPKBP1 NOTCH3

3.92e-055601261021653829
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2B TRIO ESYT1 CORO1B KIAA2013 AATK MDN1 SETD5 PKD1 MAPKBP1 CABIN1 ADAT1 EP300 PCNT

4.98e-0511051261435748872
Pubmed

Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.

CR1 CR2 IL1A

5.89e-052112638138038
Pubmed

Functional proteomics mapping of a human signaling pathway.

STIM2 KMT2B CANX LAMC1 GRN SVEP1 PKD1 NIT1 ASB2 SMAD6

6.15e-055911261015231748
Pubmed

Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.

ANKS1B HUNK IL1A

6.80e-0522126321107309
Pubmed

GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium - potential biomarkers in the detection of endometriosis - a pilot study.

GRN NOTCH3

7.78e-054126233029756
Pubmed

The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.

CR2 EP300

7.78e-054126211463834
Pubmed

Strain distribution pattern in AXB and BXA recombinant inbred strains for loci on murine chromosomes 10, 13, 17, and 18.

ARSB CSF1R

7.78e-05412628094988
Pubmed

Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood.

ITGA2B CR1

7.78e-054126236591264
Pubmed

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.

CR1 CR2

7.78e-054126216127466
Pubmed

Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response.

CANX UMOD

7.78e-054126228437467
Pubmed

Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.

PKD1 NOTCH3

7.78e-054126229463793
Pubmed

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro.

EP300 NOTCH3

7.78e-054126212391150
Pubmed

The tight skin (Tsk) mutation in the mouse, a model for human fibrotic diseases, is tightly linked to the beta 2-microglobulin (B2m) gene on chromosome 2.

FBN1 IL1A

7.78e-05412627902327
Pubmed

Weill-Marchesani Syndrome

ADAMTS10 FBN1

7.78e-054126220301293
Pubmed

Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.

HGF TECTA

7.78e-054126233976695
Pubmed

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.

CR1 CR2

7.78e-054126230217731
Pubmed

Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.

PKD1 UMOD

7.78e-054126218003909
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMC1 FBN1 NOTCH3

1.14e-0426126334189436
Pubmed

Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.

PKD1 PCNT

1.29e-045126221041232
Pubmed

A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

PKD1 PCNT

1.29e-045126219774080
Pubmed

Complement-dependent P-selectin expression and injury following ischemic stroke.

CR1 CR2

1.29e-045126217082645
Pubmed

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.

CR1 CR2

1.29e-045126220962256
Pubmed

Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.

CANX PKD1

1.29e-045126211901144
Pubmed

Tight-skin (Tsk) maps on mouse chromosome 2 within the region of linkage homology with human chromosome 15.

FBN1 IL1A

1.29e-04512627959775
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HEPH STAB1 PASK AATK CEP72 PCNT

1.77e-04225126612168954
Pubmed

Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.

CABIN1 EP300

1.93e-046126210825153
Pubmed

Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2.

CABIN1 EP300

1.93e-046126210933397
Pubmed

Loss of polycystin-1 inhibits Bicc1 expression during mouse development.

PKD1 UMOD

1.93e-046126224594709
Pubmed

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.

PKD1 UMOD

1.93e-046126217575307
Pubmed

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

PKD1 PACS2

1.93e-046126215692563
Pubmed

Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.

FBN1 IL1A

1.93e-04612627873879
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

KMT2B SHROOM2 GUCY2D PKD1 MYO18B IL3RA NOTCH3

2.05e-04329126717474147
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

RBP3 WDR81 GRN GUCY2D RP1L1 ROM1

2.14e-04233126632290105
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

ADAMTS10 FCGBP CSF1R CSMD1

2.53e-0484126415203218
Pubmed

The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.

TACC2 EP300

2.70e-047126214767476
Pubmed

EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.

LAMC1 FBN1

3.59e-048126232948785
Pubmed

Pkd1 and Pkd2 are required for normal placental development.

PKD1 UMOD

3.59e-048126220862291
Pubmed

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling.

ITGA2B IL1A

3.59e-048126222096246
Pubmed

A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder.

LAMC1 UMOD

3.59e-048126232439764
Pubmed

Genetic organization of complement receptor-related genes in the mouse.

CR1 CR2

3.59e-04812622564419
Pubmed

Autophagosomes form at ER-mitochondria contact sites.

CANX PACS2

4.61e-049126223455425
Pubmed

Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development.

CLCNKA UMOD

4.61e-049126225993027
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

TRIO TACC2 MYO18B CSMD1

5.11e-04101126418519826
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

NTRK3 PKD1L2 PKD1

5.52e-0444126319322198
Pubmed

Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.

EP300 SMAD6

5.75e-0410126216890162
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD1L2 PKD1

5.75e-0410126216805797
Pubmed

Circulating AIM prevents hepatocellular carcinoma through complement activation.

CR1 CD5L

5.75e-0410126225284781
Pubmed

Megakaryocytes compensate for Kit insufficiency in murine arthritis.

ITGA2B IL1A

5.75e-0410126228375155
Pubmed

Mapping of transcription start sites of human retina expressed genes.

RBP3 GUCY2D ROM1

5.89e-0445126317286855
Pubmed

Cytokines in the central nervous system: expression of macrophage colony stimulating factor and its receptor during development.

CSF1R IL1A

7.01e-041112628207122
Pubmed

Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.

CSF1R IL3RA

7.01e-0411126227748374
Pubmed

Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.

GRN CSF1R

7.01e-0411126212031912
Pubmed

Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.

CANX ANKS1B

7.01e-0411126231388001
Pubmed

IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins.

IL1A EP300

7.01e-0411126231953354
Pubmed

Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.

CR1 CR2

7.01e-041112621543915
Pubmed

SVEP1 is an endogenous ligand for the orphan receptor PEAR1.

LAMC1 SVEP1

7.01e-0411126236792666
Pubmed

Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.

ARSB IL1A

7.01e-041112621421760
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

STIM2 TMC2 ANKS1B TACC2 FCSK AATK UMODL1 CEP72 RP1L1 CSMD1

7.85e-048141261023251661
Pubmed

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart.

STAB1 SMAD6

8.39e-0412126218296617
Pubmed

PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins.

ESYT1 CANX

8.39e-0412126231904842
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

FNDC3B TMC2 DBF4B PGLYRP2 HEPH LMAN1L FCSK CD5L CSMD1 PDGFC TREML2

9.38e-049851261112975309
Pubmed

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.

MYO18A CR1 IL1A SMAD6

9.46e-04119126424162774
Pubmed

Alternative splice variants encoding unstable protein domains exist in the human brain.

MYO18A MAPKBP1

9.89e-0413126215491607
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

TACC2 PCNT

9.89e-0413126217920017
Pubmed

Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.

CR1 CR2

9.89e-0413126216002709
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CR1 CR2 SVEP1 SRPX2 CSMD1

4.33e-06577751179
GeneFamilyMyosins, class XVIII

MYO18A MYO18B

1.79e-0527721107
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 AATK CSF1R

6.55e-0440773321
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TRIM42 WDR81 ITGA2B AATK CSMD1

1.05e-03181775694
GeneFamilyProteases, serine

KLK7 PRSS12 PRSS36

2.45e-0363773738
CoexpressionHARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN

HGF C10orf55 ESYT1 PGLYRP2 CR1 PRSS36 STAB1 ADAMTS10 AATK CSF1R ICAM5 IL1A PDGFC NOTCH3 SMAD6

1.88e-0674012215M41202
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP LAMC1 SVEP1 PLA2R1 SRPX2 FBN1 NOTCH3

1.10e-061911247b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B ADAMTS10 FCGBP NEURL3 ASB2 RNF39 NOTCH3

1.18e-0619312478ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B ADAMTS10 FCGBP NEURL3 ASB2 RNF39 NOTCH3

1.18e-0619312470e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NTRK3 TACC2 PGPEP1L ASB2 MYO18B CSMD1 NOTCH3

1.50e-0620012479169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B TNNI3K ROM1 RNF39 IL3RA

5.22e-061571246ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B TNNI3K ROM1 RNF39 IL3RA

5.22e-061571246fddcb24776b9f86e000208bae54541b15b2adefd
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 PKD1L2 MAP3K6 PASK CSF1R PACS2

7.69e-0616812462e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF MUC5B ITGA2B ROM1 RNF39 TREML2

7.69e-0616812460e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF MUC5B ITGA2B ROM1 RNF39 TREML2

7.69e-06168124634722e14f28313f2e4644b3c1861ef12958cee9f
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRME1 SVEP1 ADAMTS10 PLA2R1 SRPX2 ADAT1

7.95e-06169124616c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF MUC5B ITGA2B ROM1 RNF39 TREML2

7.95e-061691246f2e20049a17eee533d49bd5f24a51962d123d132
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF MUC5B ITGA2B ROM1 RNF39 TREML2

7.95e-0616912464c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK3 SCTR ASB2 MYO18B CSMD1 NOTCH3

8.23e-06170124699dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK3 SCTR ASB2 MYO18B CSMD1 NOTCH3

8.23e-0617012463a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK3 SCTR ASB2 MYO18B CSMD1 NOTCH3

8.23e-061701246cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIO LAMC1 TECTA SVEP1 TNNI3K FBN1

8.80e-061721246e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS12 NTRK3 BRME1 SHROOM2 AATK CSMD1

1.04e-05177124659cf56c385c324f0844f20003d2b5049a2791e45
ToppCell3'_v3-Lung-Myeloid_Mac-Erythrophagocytic_macrophages|Lung / Manually curated celltypes from each tissue

DBF4B HEPH MS4A10 STAB1 NOTCH3 MGAM2

1.07e-051781246b63cee443cc1b7416112bf610d7c9d41e4fa37ed
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS12 HUNK AATK TMEM132E CSMD1 TMEM200C

1.07e-0517812463e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PRSS36 GPR179 STAB1 FCGBP CSF1R PDGFC

1.14e-051801246ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ESYT1 PGLYRP2 ITGA2B ROM1 IL3RA

1.18e-051811246382337427be3c11ecd03e9fa2c2e831a9674c6a7
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Papillary_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

RBP3 NBPF4 NBPF6 AATK PIP5KL1

1.24e-051071245c3695771de30bd1d4da29ae97882f6d7dfdb2242
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF KCP HUNK PKD1L2 TMEM200C PCNT

1.29e-0518412467f6c8912677764d438ab0555faca344d74c2f483
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B ZNF8 AATK CSMD1 TMEM200C TREML2

1.29e-051841246e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B HEPH FBN1 ROM1 IL3RA

1.33e-0518512465527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|343B / Donor, Lineage, Cell class and subclass (all cells)

GRN PRSS36 STAB1 FCGBP CSF1R PDGFC

1.33e-051851246d4ba36bdb8b7e3a62e827269484f89f790eaa5ef
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 ANKS1B CR1 PLA2R1 TMEM200C

1.41e-05187124624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 ANKS1B CR1 PLA2R1 TMEM200C

1.46e-0518812469db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 ANKS1B CR1 PLA2R1 TMEM200C

1.46e-051881246047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

GRN CD5L CSF1R IL1A PDGFC NOTCH3

1.50e-051891246aac79c41ce7acba722c45c016b2c6997fb772a96
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF LAMC1 SVEP1 SRPX2 FBN1 MDN1

1.55e-0519012461121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF LAMC1 SVEP1 SRPX2 FBN1 MDN1

1.55e-051901246048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 SVEP1 SRPX2 FBN1

1.55e-05190124612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NTRK3 SCTR ASB2 CSMD1 PDGFC NOTCH3

1.55e-05190124673d94fbae92029745989a8712eed8b99fd84c193
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 SVEP1 SRPX2 FBN1

1.59e-05191124670c067c54084bfb02c29bab085f4defd477194fb
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3B KCP LAMC1 SVEP1 SRPX2 FBN1

1.64e-051921246671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 ANKS1B CR1 PLA2R1 TMEM200C

1.64e-051921246ef0aba777072429a6ab7dcfcc305673975946580
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRN PRSS36 STAB1 CD5L CSF1R IL3RA

1.64e-051921246935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK3 SCTR ASB2 MYO18B CSMD1 NOTCH3

1.64e-051921246bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK3 SCTR ASB2 MYO18B CSMD1 NOTCH3

1.64e-051921246b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MUC5B ADAMTS10 FCGBP ASB2 RNF39 NOTCH3

1.64e-051921246c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3B KCP LAMC1 SVEP1 SRPX2 FBN1

1.64e-051921246840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 ANKS1B CR1 PLA2R1 TMEM200C

1.69e-0519312463eaa0461618582a1754400624350d269d24e750a
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 SVEP1 SRPX2 FBN1

1.69e-051931246dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 SVEP1 SRPX2 FBN1

1.74e-05194124611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

FNDC3B ANKS1B LAMC1 SVEP1 SRPX2 FBN1

1.79e-051951246f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell10x5'v1-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRN STAB1 FCGBP CD5L NEURL3 CSF1R

1.85e-051961246e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRN STAB1 FCGBP CD5L NEURL3 CSF1R

1.85e-0519612463bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCell390C-Myeloid-Monocyte-CD16+_Monocyte|390C / Donor, Lineage, Cell class and subclass (all cells)

GRN CR1 STAB1 CSF1R IL1A IL3RA

1.90e-05197124601f5f5c34e904cc0146e978cc05ed1cd86a41533
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF NTRK3 LAMC1 SVEP1 SRPX2 FBN1

1.90e-0519712469b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF LAMC1 SVEP1 SRPX2 FBN1 MDN1

1.95e-051981246a860246bcea847249a78fd2e86ed8e04371060db
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

SSPOP STAB1 FCGBP CSF1R IL1A PDGFC

1.95e-051981246e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

SSPOP STAB1 FCGBP CSF1R IL1A PDGFC

1.95e-051981246a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYO18A KCP STAB1 FCGBP CSF1R PDGFC

2.01e-051991246514dbf128b6832b1cbd65be023d4fe02400e8dec
ToppCellSevere_COVID-19-Myeloid-MoAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ARRDC4 GRN CR1 STAB1 CSF1R IL3RA

2.01e-05199124630523cf08815ca214877e33a2c52197ff8318557
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARRDC4 GRN CR1 STAB1 CSF1R IL3RA

2.01e-051991246105709b97c55826a852aed27658e3b4af1738c8a
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS12 MUC5B FCGBP NEURL3 ASB2 RNF39

2.01e-0519912462b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARRDC4 GRN CR1 STAB1 CSF1R IL3RA

2.01e-0519912460892957a49304ce4b6daa3657d76d8365ce0dd19
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARRDC4 GRN CR1 STAB1 CSF1R IL3RA

2.01e-051991246b2dc3d0af6ecd3ab01779aaa1f061cb0f941cae8
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Club|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRSS12 MUC5B FCGBP NEURL3 ASB2 RNF39

2.01e-051991246111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS12 MUC5B FCGBP NEURL3 ASB2 RNF39

2.01e-051991246d583290a1d288b749ad17bc501c1487268c6551c
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARRDC4 GRN CR1 STAB1 CSF1R IL3RA

2.01e-051991246961ad44199871be8e09d31904d383edc865ba262
ToppCellBAL-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

ARRDC4 GRN STAB1 CSF1R PDGFC IL3RA

2.01e-051991246d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NTRK3 TACC2 SCTR ASB2 CSMD1 NOTCH3

2.07e-052001246a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

NTRK3 TACC2 SCTR MYO18B CSMD1 NOTCH3

2.07e-0520012467c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRN STAB1 AATK FCGBP CD5L CSF1R

2.07e-052001246af743dfef7e7cfaef1c494999757123f93a213e3
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Nos1_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

HGF KLK7 STIM2 RBP3 FCGBP

2.96e-0512812459128b633879d21de2ebe651384cfec6d2c3c2932
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

POLM MAP3K6 STAB1 DDX11 OSGIN1

7.59e-05156124563b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN AATK CD5L CSF1R P2RY4

8.06e-051581245d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN AATK CD5L CSF1R P2RY4

8.06e-051581245df614450e10629dc9115d7365397663e82f9e48f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PGLYRP2 HUNK NUDCD2 DDX11 SRPX2

8.06e-051581245d72d6527dc50207ddbada262460d3c4bac249a19
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HGF DBF4B NTRK3 CORO1B PDGFC

8.55e-051601245c2b5fadb4bac17fafc08831f6d3f4ff96ada7e70
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

ADAMTS10 FBN1 AATK IL1A OSGIN1

8.81e-0516112457a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5B DDX11 ADAMTS10 FCGBP NOTCH3

8.81e-051611245bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYO18A PON2 ADAMTS10 AATK NEURL3

8.81e-05161124578cc5bc488bc47726195a649946d414e6bfabf94
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO18A PON2 ADAMTS10 AATK NEURL3

9.07e-0516212450fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B ROM1 RNF39 IL3RA

1.02e-041661245c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B ROM1 RNF39 IL3RA

1.02e-0416612450975fc165bcc7e85f053d9d0244fffe407c23571
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

HGF PLA2R1 MYCNOS CSMD1 RNF39

1.02e-04166124520f248d95c86eb52a1efe9abe73123fbe4206caf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLK7 ARRDC4 CR1 PLA2R1 TMEM200C

1.14e-04170124560bbd738c12e64e483485586c30057304884f5a6
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CD5L CSMD1 RNF39 PDGFC

1.14e-041701245a121e10099faaeb60251eec162f38caf7c4238c2
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NTRK3 SCTR CSMD1 PDGFC NOTCH3

1.17e-0417112454ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

KLHL35 STAB1 FCGBP CSF1R ROM1

1.20e-041721245f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP2 NEURL3 SPACA1 ASB2 CABIN1

1.23e-0417312456e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WDR81 STAB1 CSF1R ASB2 IL1A

1.23e-04173124512c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP2 NEURL3 SPACA1 ASB2 CABIN1

1.23e-0417312454c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCellLPS-antiTNF-Lymphocytic_B|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POLM CR1 CR2 PVRIG TREML2

1.27e-041741245cc493654ea3517bc6a145c7f787f304929636f86
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POLM CR1 CR2 PVRIG TREML2

1.27e-0417412459eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POLM CR1 CR2 PVRIG TREML2

1.27e-041741245b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF HUNK SSPOP GPR179 NOTCH3

1.30e-0417512452a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZNF772 STAB1 DDX11 FCGBP AFDN-DT

1.30e-041751245bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

KLK7 ARRDC4 CR1 PLA2R1 TMEM200C

1.30e-041751245a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF HUNK SSPOP GPR179 NOTCH3

1.30e-041751245fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIO FCGBP NEURL3 MDN1 EP300

1.30e-041751245dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRN CR1 STAB1 FCGBP CSF1R

1.37e-041771245382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLK7 TCERG1L PRSS12 SCTR ASB2

1.37e-041771245f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PRSS12 NTRK3 FBN1 SCTR NOTCH3

1.37e-0417712455cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGF SVEP1 HEPH FBN1 CD5L

1.37e-041771245b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ITGA2B ROM1 RNF39 IL3RA

1.37e-041771245c1f838e425ebb04482829b1957e3c1347127e6de
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

SVEP1 HEPH ADAMTS10 SRPX2 FBN1

1.41e-041781245142879e9393e721f9b05a6bb46995c9d6d713c95
DiseaseDementia

GRN CSF1R NOTCH3

4.28e-05171203C0497327
DiseaseWeill-Marchesani syndrome

ADAMTS10 FBN1

4.91e-0531202C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

ADAMTS10 FBN1

4.91e-0531202C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

ADAMTS10 FBN1

4.91e-0531202C1869114
DiseaseWeill-Marchesani syndrome (implicated_via_orthology)

ADAMTS10 FBN1

4.91e-0531202DOID:0050475 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

ADAMTS10 FBN1 PKD1 SMAD6

6.53e-05531204C4707243
DiseaseWeill-Marchesani syndrome

ADAMTS10 FBN1

9.79e-0541202cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

ADAMTS10 FBN1

9.79e-0541202DOID:0050475 (is_implicated_in)
Diseasekeratoconus (is_implicated_in)

HGF IL1A

2.43e-0461202DOID:10126 (is_implicated_in)
DiseasePolyomavirus Infections

HGF GPR179

3.40e-0471202C0949804
Diseaseamino acid measurement

ARRDC4 TACC2 PASK PLA2R1 MYCNOS RP1L1 CSMD1 PDGFC MGAM2 OSGIN1

4.62e-0467812010EFO_0005134
Diseasehypertrophic cardiomyopathy

FNDC3B KCP CLCNKA PKD1

5.52e-04921204EFO_0000538
DiseaseMarfan Syndrome, Type I

LAMC1 FBN1

5.80e-0491202C4721845
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

GRN CLCNKA

7.23e-04101202DOID:12387 (implicated_via_orthology)
Diseasecholesteatoma (is_marker_for)

HGF IL1A

7.23e-04101202DOID:869 (is_marker_for)
Diseaseinterstitial lung disease (is_implicated_in)

HGF IL1A

7.23e-04101202DOID:3082 (is_implicated_in)
DiseaseRETINITIS PIGMENTOSA

RBP3 ROM1

7.23e-04101202268000
DiseaseLeukemia, Myelocytic, Acute

HGF TRIO NTRK3 CSF1R EP300

7.24e-041731205C0023467
Diseaseneurotic disorder

ARRDC4 AATK MYCNOS CSMD1

7.84e-041011204EFO_0004257
Diseaseurokinase-type plasminogen activator measurement

C10orf55 IRGC

8.81e-04111202EFO_0010803
DiseaseHemolytic-Uremic Syndrome

DGKE IL1A

8.81e-04111202C0019061
DiseaseMarfan Syndrome

LAMC1 FBN1

8.81e-04111202C0024796
Diseasegranulins measurement

GRN ITGA2B

1.05e-03121202EFO_0008141
Diseasecalcium measurement

HGF STIM2 MYO18A WDR81 KCP HEPH NEURL3 MYO18B OSGIN1

1.09e-036281209EFO_0004838
Diseaseesophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement

CEP72 RP1L1

1.24e-03131202EFO_0000280, EFO_0000478, EFO_0008343
DiseaseMetastatic melanoma

TRIO PASK GUCY2D

1.40e-03541203C0278883
Diseaseurokinase plasminogen activator surface receptor measurement

C10orf55 IRGC

1.45e-03141202EFO_0010932
DiseaseImpaired cognition

CR1 NOTCH3

1.45e-03141202C0338656
Diseasehepcidin:ferritin ratio

TACC2 FBN1 GPR61

1.48e-03551203EFO_0007901
Diseasenasopharynx carcinoma (is_implicated_in)

CR2 CSF1R

1.66e-03151202DOID:9261 (is_implicated_in)
DiseaseAcute Myeloid Leukemia, M1

HGF TRIO NTRK3 CSF1R

1.73e-031251204C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

HGF TRIO NTRK3 CSF1R

1.73e-031251204C1879321
DiseaseDisorder of eye

RBP3 GRN GPR179 GUCY2D ROM1

1.78e-032121205C0015397
Diseasesystolic blood pressure, alcohol drinking

KIAA2013 LMAN1L FBN1 RP1L1

1.88e-031281204EFO_0004329, EFO_0006335
Diseasecortical thickness

KMT2B ARRDC4 PRSS12 LAMC1 TACC2 STAB1 LMAN1L FBN1 UMODL1 SETD5 PKD1 PDGFC

1.96e-03111312012EFO_0004840
Diseasegraft-versus-host disease (is_implicated_in)

HGF IL1A

2.14e-03171202DOID:0081267 (is_implicated_in)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B TRIO

2.14e-03171202DOID:0060307 (is_implicated_in)
Diseasecholangiocarcinoma (is_marker_for)

HGF MUC5B RNF39

2.28e-03641203DOID:4947 (is_marker_for)
DiseaseAlzheimer disease, polygenic risk score

PRSS12 NBPF4 TACC2 CR1 CDKL1 PLA2R1 IRGC TREML2

2.78e-035861208EFO_0030082, MONDO_0004975
Diseaseprogranulin measurement

GRN ITGA2B

3.59e-03221202EFO_0004625
Diseasetriacylglycerol 58:9 measurement

TMEM132E CSMD1

3.59e-03221202EFO_0010443
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

EP300 SMAD6

3.92e-03231202DOID:0050156 (is_marker_for)
DiseaseQRS duration, response to sulfonylurea

MDN1 CSMD1

3.92e-03231202EFO_0005055, EFO_0007922

Protein segments in the cluster

PeptideGeneStartEntry
CEGDSPGNETWATSP

UMODL1

941

Q5DID0
PTVPGCPGAWDVDSE

ESYT1

606

Q9BSJ8
TTGHIWACPPSEGDD

EP300

1431

Q09472
VWSSTVPRCEAPCGG

CSMD1

746

Q96PZ7
CEFVSAPEVSRWAGP

ASB2

541

Q96Q27
AQGRWSALSEGPCAP

AFDN-DT

196

Q9Y6Z5
LTSGEWGCCPIPEAV

GRN

381

P28799
PTVCGHTGPVLDIDW

CORO1B

76

Q9BR76
REATLQDCPSGPWGK

CD5L

211

O43866
IAECEWDLGRPPGST

CEP72

201

Q9P209
CVPFGSRPEGVDGAW

ADAMTS10

536

Q9H324
DSPGRLVPCGAAISW

ADAT1

386

Q9BUB4
GRATAAWGPSTCPRA

ARRDC4

61

Q8NCT1
AVGGSTRPCPSWKAV

POLM

401

Q9NP87
LVPDSRKDGCWAPTG

MUC5B

5251

Q9HC84
PTEAACPQGTWSGDL

NBPF4

476

Q96M43
VEEPSDGTILGRWCG

PDGFC

111

Q9NRA1
ENTCGPSGLWEALTP

ANKS1B

396

Q7Z6G8
WVCLAGGPPSITDFQ

IL1A

251

P01583
GEPWVSVTDFGAPCL

PRSS12

96

P56730
VGNESGCGERTLDPW

PASK

411

Q96RG2
TIPEWCQGAAPSGLE

MDN1

4036

Q9NU22
KGCEVSRWVDPAPEG

PIP5KL1

221

Q5T9C9
RVSWEEGAPSVPPGC

GPR61

181

Q9BZJ8
VCWGGETDASNPAPA

MYCNOS

26

P40205
RGCLWEDTSTPGVPT

MGAM2

931

Q2M2H8
EERSGVVPCGTPWGQ

NUDCD2

6

Q8WVJ2
CNGSGSPLPDVDWIV

NTRK3

231

Q16288
TKAEPCPWEASEGGE

GPR179

1376

Q6PRD1
GGRAADVCPWDVPDA

GPR179

1991

Q6PRD1
VGVLGPWACDPIFSR

GUCY2D

56

Q02846
GCPWTQAEGTTAPAV

GUCY2D

151

Q02846
GGWALDASCQIPSTP

LMAN1L

351

Q9HAT1
PRSGAERAGSCWQDP

MAP3K6

6

O95382
PGGNFTLTCRAEAWP

ICAM5

761

Q9UMF0
CFLPVAEGWAGEPRS

MYO18A

1046

Q92614
ADIRSFWPEGGVCLP

PGPEP1L

76

A6NFU8
ASWSTEACPELPGRG

PERCC1

241

A0A1W2PR82
PDLGTEGCWDQLSAP

PGLYRP2

241

Q96PD5
VPTAVTAWRGDCPSA

MS4A10

186

Q96PG2
GWTGPRCEAPAAAPE

NOTCH3

1366

Q9UM47
RCEPPGTTCTVSGWG

KLK7

136

P49862
LEPWPVGCAGDETES

MYCLP1

56

P12525
WGPSRGCVPEEESSD

KMT2B

101

Q9UMN6
RGEEGGPWCFTSNPE

HGF

181

P14210
ATWEVDGSSPSCVPR

PACS2

26

Q86VP3
VWSPECCQDPGTGVS

DDX11

946

Q96FC9
GGKTQEVPTACPDWR

PCNT

2436

O95613
DVTLWDLPGAGSPGC

IRGC

106

Q6NXR0
TWDDSGCQVGPRTSP

PKD1L2

1291

Q7Z442
DDPVIPGSGWGTCVA

PRR35

536

P0CG20
PGPGSSEVELDCWFD

P2RY4

16

P51582
SIDPSSGDIWVGCHP

PON2

271

Q15165
DWGPDGEETETQTCP

PRSS36

566

Q5K4E3
AWPGASCAETPAREA

OTULIN

11

Q96BN8
CPARVDFSGGWSDTP

FCSK

711

Q8N0W3
SIPWGCRDPGAQVFA

CEFIP

346

Q711Q0
RCVGNGSVEWDGPPS

CSF1R

41

P07333
SCSWAVGPGAPADVQ

IL3RA

121

P26951
SWCLEPGSVAQGSPD

BRME1

296

Q0VDD7
CWPAEAALGTGAEPT

CABIN1

2051

Q9Y6J0
PPSSRCVIAGQGVAW

CR2

251

P20023
GSPVCLEAWDPASAG

FFAR1

166

O14842
GNGVWSSPAPRCELS

CR1

1376

P17927
VNDSEWVPGPTDDRC

ERVK-24

16

P61566
GPPVDVWAIGCVFAE

CDKL1

181

Q00532
AGLPRWSGSPASDCD

DBF4B

351

Q8NFT6
SWQEETRPGCGATEP

FCGBP

1031

Q9Y6R7
DAGRCWSPGVTVAPE

FBN1

361

P35555
SCTPDGCVLVGWESP

FNDC3B

776

Q53EP0
ACEGSFLPAWVSGVP

HUNK

31

P57058
ESAPGCGVWQRPVID

CANX

361

P27824
TERWACLGEGTTPKP

MAPKBP1

1341

O60336
AQDPRCDPKATGVWG

ARSB

516

P15848
GVPATWVESCTCPVG

LAMC1

681

P11047
DGEPWAQGPCTVTIT

DGKE

521

P52429
RGPTDCGWGKPISES

SPACA1

116

Q9HBV2
DPWGTVVARCSEGPG

NIT1

276

Q86X76
VGCWTPASSAPRAAV

C3orf56

156

Q8N813
VEWGTPDPSSCGAQD

OSGIN1

201

Q9UJX0
WPGGSVSARFENVCP

PKD1

861

P98161
QWAVVGDTFPVGCRP

MIOX

136

Q9UGB7
GPGQWSDICKVVTPD

TRIM42

686

Q8IWZ5
APPAAGTECLISGWG

PRSS3P2

131

Q8NHM4
LWPQGCVSGPSADSV

TREML2

11

Q5T2D2
SWESLEPGEVVTGPC

SSPOP

3611

A2VEC9
GGPGWLPESDCETVT

SMAD6

111

O43541
GGDAEGASCSWQRPP

TMEM200C

391

A6NKL6
EEDLGWGCPDVAGPT

TMEM132E

1041

Q6IEE7
RCPESWDPVSAGGHA

AATK

691

Q6ZMQ8
PTEAACPQGTWSGDL

NBPF6

476

Q5VWK0
AEGVQWEPDGRPCTA

KCP

436

Q6ZWJ8
ERSGPGPNDSACVSW

HEPH

866

Q9BQS7
GETVPTWCPCGLSQD

SETD5

86

Q9C0A6
WADGESSRICPQETP

SHROOM2

571

Q13796
PSQEETGGVFLCPWR

ITGA2B

76

P08514
NGSWSGATPDCVPVR

SVEP1

2876

Q4LDE5
WGFCPDPTSAEVGCD

PLA2R1

216

Q13018
ECPTWNPGPRSEGSE

ADGRD2

331

Q7Z7M1
ARCPDPGEHSSTWGE

CLBA1

66

Q96F83
FSGDPVTLQELWGPC

CLCNKA

11

P51800
CPISWGESGPAVDGI

C10orf55

131

Q5SWW7
DGPLWECGTVVDPTA

TECTA

531

O75443
PGSPWCVVWTGDDRV

TCERG1L

341

Q5VWI1
WEGSGVLPCVGTPAE

RBP3

296

P10745
DWVSVVTPARDGPCG

UMOD

376

P07911
EAQRGPSPEASWLCG

RP1L1

836

Q8IWN7
TAWLQGGVACRPAPE

ROM1

321

Q03395
PVTVDVSWGSPDCVG

STIM2

641

Q9P246
DGRWSGGEPVCVDID

SRPX2

166

O60687
GWSETFPRPNLACGV

SCTR

111

P47872
GCIASGEWPTQLDVP

PPAT

16

Q06203
PEGSQEQGSPEACWR

STAB1

1896

Q9NY15
GPVWLDEVGCRGSEA

SCART1

846

Q4G0T1
PSCPGEGWIRGAASE

TACC2

806

O95359
GWPGSRGQEAEEPCS

MYO18B

436

Q8IUG5
PTWAAVLPEGCALTG

NEURL3

106

Q96EH8
ASVGGPERCHDSWFP

UBR3

971

Q6ZT12
AERGTTQGCHPAWEP

ZNF8

86

P17098
PADVPRGSCWETAVG

TMC2

566

Q8TDI7
GWNACPEGRPEFSEV

TNNI3K

701

Q59H18
EGSWEACGSLPPSSD

PVRIG

141

Q6DKI7
AVATETPGGSDPGCW

ZNF772

96

Q68DY9
TPCEASWTRDRPVAG

WDR81

641

Q562E7
PWTRKEDLSQGTCPG

ZNF805

71

Q5CZA5
QPEAGPWSCSGVILS

TYSND1

26

Q2T9J0
ECGTVWGSGVAVAPR

TYSND1

351

Q2T9J0
TDQCPAAEGWIPGFV

TRIO

2596

O75962
CLARRWGTPPATGTE

RNF39

111

Q9H2S5
WGEAAVLPSPVESCG

KLHL35

511

Q6PF15
PWSRGEPGAAEPSAC

KIAA2013

51

Q8IYS2