Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamine N-acyltransferase activity

GLYATL1 GLYATL1B

4.11e-062412GO:0047946
GeneOntologyMolecularFunctionglycine N-acyltransferase activity

GLYATL1 GLYATL1B

4.10e-055412GO:0047961
GeneOntologyMolecularFunctionMAP kinase activity

MAPK14 MAPK11

4.85e-0416412GO:0004707
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRM PTPRR

5.49e-0417412GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRM PTPRR

5.49e-0417412GO:0019198
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

GLUL GLYATL1 GLYATL1B PAFAH1B2

1.41e-03238414GO:0016747
GeneOntologyBiologicalProcessglutamine metabolic process

GLUL GLYATL1 GLYATL1B

2.65e-0530403GO:0006541
GeneOntologyBiologicalProcessregulation of epithelial cell migration

GLUL DOCK1 MAPK14 PTPRM PTPRR EPHA2

4.90e-05344406GO:0010632
GeneOntologyBiologicalProcesspositive regulation of interleukin-12 production

MAPK14 MAPK11 CD36

1.17e-0449403GO:0032735
GeneOntologyBiologicalProcessresponse to lipoteichoic acid

MAPK14 CD36

1.63e-0410402GO:0070391
GeneOntologyBiologicalProcesscellular response to lipoteichoic acid

MAPK14 CD36

1.63e-0410402GO:0071223
GeneOntologyBiologicalProcessepithelial cell migration

GLUL DOCK1 MAPK14 PTPRM PTPRR EPHA2

1.71e-04432406GO:0010631
GeneOntologyBiologicalProcessepithelium migration

GLUL DOCK1 MAPK14 PTPRM PTPRR EPHA2

1.78e-04435406GO:0090132
GeneOntologyBiologicalProcesstissue migration

GLUL DOCK1 MAPK14 PTPRM PTPRR EPHA2

1.91e-04441406GO:0090130
GeneOntologyBiologicalProcesscellular response to UV-B

MAPK14 MAPK11

2.39e-0412402GO:0071493
GeneOntologyBiologicalProcessregulation of interleukin-12 production

MAPK14 MAPK11 CD36

3.52e-0471403GO:0032655
GeneOntologyBiologicalProcessinterleukin-12 production

MAPK14 MAPK11 CD36

3.82e-0473403GO:0032615
DomainFN3_dom

IFNGR1 IL20RA ASTN2 POMGNT2 PTPRM EPHA2

5.11e-06209406IPR003961
DomainMAPK_p38

MAPK14 MAPK11

2.68e-054402IPR008352
DomainFN3

IL20RA ASTN2 POMGNT2 PTPRM EPHA2

6.35e-05199405PS50853
DomainMAP_kinase_CS

MAPK14 MAPK11

2.91e-0412402IPR003527
DomainTissue_fac

IFNGR1 IL20RA

2.91e-0412402PF01108
DomainMAPK

MAPK14 MAPK11

2.91e-0412402PS01351
DomainTissue_factor

IFNGR1 IL20RA

2.91e-0412402IPR001187
DomainKinase-like_dom

STK36 MAPK14 MAPK11 PIK3C2G EPHA2 NIM1K

9.63e-04542406IPR011009
DomainCupredoxin

CP PADI4

1.01e-0322402IPR008972
DomainProtein_kinase_ATP_BS

STK36 MAPK14 MAPK11 EPHA2 NIM1K

1.23e-03379405IPR017441
Domain-

IFNGR1 IL20RA ASTN2 POMGNT2 PTPRM EPHA2

2.68e-036634062.60.40.10
DomainPTPc

PTPRM PTPRR

2.69e-0336402SM00194
DomainPROTEIN_KINASE_ATP

STK36 MAPK14 MAPK11 EPHA2 NIM1K

2.84e-03459405PS00107
DomainTYR_PHOSPHATASE_PTP

PTPRM PTPRR

3.15e-0339402PS50055
DomainPTPase_domain

PTPRM PTPRR

3.48e-0341402IPR000242
DomainY_phosphatase

PTPRM PTPRR

3.48e-0341402PF00102
DomainIg-like_fold

IFNGR1 IL20RA ASTN2 POMGNT2 PTPRM EPHA2

3.66e-03706406IPR013783
DomainProt_kinase_dom

STK36 MAPK14 MAPK11 EPHA2 NIM1K

3.73e-03489405IPR000719
DomainBTB-kelch_protein

KLHL12 KLHL23

3.82e-0343402IPR017096
DomainPROTEIN_KINASE_DOM

STK36 MAPK14 MAPK11 EPHA2 NIM1K

3.86e-03493405PS50011
DomainKelch

KLHL12 KLHL23

6.85e-0358402SM00612
DomainSer/Thr_kinase_AS

STK36 MAPK14 MAPK11 NIM1K

6.97e-03357404IPR008271
DomainPTPc_motif

PTPRM PTPRR

7.08e-0359402SM00404
DomainTyr_Pase_cat

PTPRM PTPRR

7.08e-0359402IPR003595
DomainGal_Oxase/kelch_b-propeller

KLHL12 KLHL23

7.08e-0359402IPR011043
DomainS_TKc

STK36 MAPK14 MAPK11 NIM1K

7.11e-03359404SM00220
DomainFN3

ASTN2 PTPRM EPHA2

7.22e-03185403SM00060
DomainBACK

KLHL12 KLHL23

7.32e-0360402SM00875
DomainPROTEIN_KINASE_ST

STK36 MAPK14 MAPK11 NIM1K

7.32e-03362404PS00108
DomainBACK

KLHL12 KLHL23

7.56e-0361402PF07707
DomainBACK

KLHL12 KLHL23

7.56e-0361402IPR011705
PathwayWP_REGULATORY_CIRCUITS_OF_STAT3_SIGNALING

IFNGR1 IL20RA MAPK14 MAPK11

2.44e-0578314M39824
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY

MAPK14 MAPK11

6.98e-056312M47766
PathwayBIOCARTA_TSP1_PATHWAY

MAPK14 CD36

9.76e-057312M22039
PathwayBIOCARTA_TSP1_PATHWAY

MAPK14 CD36

9.76e-057312MM1559
PathwayREACTOME_P38MAPK_EVENTS

MAPK14 MAPK11

9.76e-057312MM14672
PathwayWP_IL26_SIGNALING

MPO IL20RA MAPK14

1.46e-0447313M48074
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK14 MAPK11

2.08e-0410312MM15135
PathwayREACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION

MAPK14 MAPK11

2.08e-0410312M27146
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK14 MAPK11

2.08e-0410312M13962
PathwayREACTOME_SIGNALLING_TO_RAS

MAPK14 MAPK11

3.05e-0412312MM14657
PathwayREACTOME_P38MAPK_EVENTS

MAPK14 MAPK11

3.60e-0413312M1441
PathwayKEGG_LEISHMANIA_INFECTION

IFNGR1 MAPK14 MAPK11

5.18e-0472313M3126
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

IFNGR1 MAPK14 MAPK11

5.84e-0475313M39568
PathwayREACTOME_KSRP_KHSRP_BINDS_AND_DESTABILIZES_MRNA

MAPK14 MAPK11

6.24e-0417312M959
PathwayREACTOME_ERK_MAPK_TARGETS

MAPK14 MAPK11

7.82e-0419312MM14780
PathwayREACTOME_SIGNALLING_TO_RAS

MAPK14 MAPK11

8.68e-0420312M12256
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP

MAPK14 PTPRR

8.68e-0420312M47928
PathwayPID_P38_MK2_PATHWAY

MAPK14 MAPK11

9.58e-0421312M199
PathwayBIOCARTA_NTHI_PATHWAY

MAPK14 MAPK11

1.05e-0322312MM1443
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_APOPTOSIS

MAPK14 MAPK11

1.05e-0322312M39902
PathwayREACTOME_ERK_MAPK_TARGETS

MAPK14 MAPK11

1.05e-0322312M13408
PathwayWP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING

MAPK14 MAPK11

1.15e-0323312M39709
PathwayREACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION

MAPK14 MAPK11

1.15e-0323312M17243
PathwayWP_LDL_INFLUENCE_ON_CD14_AND_TLR4

MAPK14 MAPK11

1.15e-0323312M45556
PathwayBIOCARTA_NTHI_PATHWAY

MAPK14 MAPK11

1.15e-0323312M2821
PathwayWP_PHYSIOLOGICAL_AND_PATHOLOGICAL_HYPERTROPHY_OF_THE_HEART

MAPK14 MAPK11

1.25e-0324312M39576
PathwayREACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION

MAPK14 MAPK11

1.25e-0324312MM15133
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

MAPK14 MAPK11

1.25e-0324312M27553
PathwayREACTOME_MYOGENESIS

MAPK14 MAPK11

1.25e-0324312MM15174
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

MAPK14 MAPK11

1.36e-0325312MM15269
PathwayPID_LYMPH_ANGIOGENESIS_PATHWAY

MAPK14 MAPK11

1.36e-0325312M274
PathwayREACTOME_SIGNALING_BY_VEGF

DOCK1 MAPK14 MAPK11

1.47e-03103313MM14752
PathwayREACTOME_SIGNALLING_TO_ERKS

MAPK14 MAPK11

1.47e-0326312MM14716
PathwayPID_P38_MKK3_6PATHWAY

MAPK14 MAPK11

1.47e-0326312M20
PathwayKEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY

MAPK14 MAPK11

1.47e-0326312M47565
PathwayWP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION

MAPK14 MAPK11

1.59e-0327312M39838
PathwayREACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

MAPK14 MAPK11

1.59e-0327312MM14779
PathwayREACTOME_SIGNALING_BY_VEGF

DOCK1 MAPK14 MAPK11

1.59e-03106313M27077
PathwayWP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING

MAPK14 MAPK11

1.71e-0328312M39572
PathwayREACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES

MAPK14 MAPK11

1.71e-0328312MM15132
PathwayWP_IL19_SIGNALING

IL20RA MAPK14

1.71e-0328312M48111
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

MAPK14 MAPK11

1.83e-0329312M39676
PathwayREACTOME_MYOGENESIS

MAPK14 MAPK11

1.83e-0329312M853
PathwayPID_P38_ALPHA_BETA_PATHWAY

MAPK14 MAPK11

1.96e-0330312M76
PathwayREACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE

MAPK14 MAPK11 CD36

2.01e-03115313M27013
PathwayPID_CD40_PATHWAY

MAPK14 MAPK11

2.09e-0331312M45
PathwayREACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES

MAPK14 MAPK11

2.09e-0331312M15195
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

MAPK14 MAPK11 PIK3C2G

2.17e-03118313M39852
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY

MAPK14 MAPK11

2.37e-0333312M47550
PathwayREACTOME_NOD1_2_SIGNALING_PATHWAY

MAPK14 MAPK11

2.37e-0333312MM14663
PathwayBIOCARTA_FMLP_PATHWAY

MAPK14 PIK3C2G

2.51e-0334312M10287
PathwaySIG_CD40PATHWAYMAP

MAPK14 MAPK11

2.51e-0334312M12705
PathwayREACTOME_SIGNALLING_TO_ERKS

MAPK14 MAPK11

2.51e-0334312M13881
PathwayBIOCARTA_FMLP_PATHWAY

MAPK14 PIK3C2G

2.51e-0334312MM1399
PathwayREACTOME_NOD1_2_SIGNALING_PATHWAY

MAPK14 MAPK11

2.81e-0336312M1059
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAPK14 MAPK11

2.81e-0336312M39908
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

MAPK14 MAPK11

2.97e-0337312MM14899
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

MAPK14 MAPK11 PIK3C2G

2.98e-03132313M39338
PathwayPID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY

MAPK14 MAPK11

3.13e-0338312M229
PathwayPID_FAS_PATHWAY

MAPK14 MAPK11

3.13e-0338312M94
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

MPO MAPK14 ACTR2 CD36 PAFAH1B2

3.60e-03478315M27620
PathwayPID_CXCR3_PATHWAY

MAPK14 MAPK11

4.00e-0343312M222
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

DOCK1 MAPK14 MAPK11 ACTR2 EPHA2

4.43e-03502315MM14537
PathwayREACTOME_TOLL_LIKE_RECEPTOR_CASCADES

MAPK14 MAPK11 CD36

4.68e-03155313MM14665
PathwayWP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE

MAPK14 MAPK11

4.76e-0347312M39518
PathwayPID_IL6_7_PATHWAY

MAPK14 MAPK11

4.76e-0347312M183
PathwayREACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS

MAPK14 MAPK11

4.76e-0347312MM14664
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

MPO MAPK14 ACTR2 CD36 PAFAH1B2

4.78e-03511315MM15330
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

MPO DOCK1 MAPK14 MAPK11 ACTR2 CD36 PAFAH1B2

5.02e-03995317MM14661
PathwayWP_INSULIN_SIGNALING

MAPK14 MAPK11 PIK3C2G

5.11e-03160313M39482
PathwayWP_INSULIN_SIGNALING

MAPK14 MAPK11 PIK3C2G

5.11e-03160313MM15956
PathwayWP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY

MAPK14 MAPK11

5.16e-0349312M39543
Pubmed

Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.

MAPK14 MAPK11

1.36e-06241229357353
Pubmed

Counter-regulation of T cell effector function by differentially activated p38.

MAPK14 MAPK11

1.36e-06241224863062
Pubmed

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

MPO CP

1.36e-0624129097926
Pubmed

Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species.

MPO CD36

1.36e-06241210772654
Pubmed

Intrinsically active variants of all human p38 isoforms.

MAPK14 MAPK11

1.36e-06241217241234
Pubmed

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia.

IFNGR1 SYNE2

1.36e-06241226066746
Pubmed

p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development.

MAPK14 MAPK11

1.36e-06241227605380
Pubmed

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.

MAPK14 MAPK11

1.36e-06241219955483
Pubmed

The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell.

MAPK14 MAPK11

1.36e-06241215824134
Pubmed

The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning.

MAPK14 MAPK11

1.36e-06241220188737
Pubmed

Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation.

MAPK14 MAPK11

1.36e-06241217105766
Pubmed

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice.

MAPK14 MAPK11

1.36e-06241224531379
Pubmed

p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart.

MAPK14 MAPK11

1.36e-06241232573492
Pubmed

Effect of p38 MAP kinases on contractility and ischemic injury in intact heart.

MAPK14 MAPK11

1.36e-06241219706373
Pubmed

Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.

MPO CP

1.36e-06241223306200
Pubmed

Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells.

MAPK14 MAPK11

1.36e-06241231661126
Pubmed

Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other.

MPO CP

1.36e-06241219031316
Pubmed

p38α and p38β mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons.

MAPK14 MAPK11

1.36e-06241221865449
Pubmed

EphA2 modulates radiosensitive of hepatocellular carcinoma cells via p38/mitogen-activated protein kinase-mediated signal pathways.

MAPK14 EPHA2

1.36e-06241226520689
Pubmed

Interferon-alpha induces the growth inhibition of human T-cell leukaemia line Jurkat through p38alpha and p38beta.

MAPK14 MAPK11

1.36e-06241220053787
Pubmed

The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation.

MAPK14 MAPK11

4.06e-06341231780731
Pubmed

Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells.

MAPK14 MAPK11

4.06e-06341224673557
Pubmed

The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes.

MAPK14 MAPK11

4.06e-06341217210568
Pubmed

Relationship between maternal blood ceruloplasmin level, catalase and myeloperoxidase activity and neural tube defects.

MPO CP

4.06e-06341228397206
Pubmed

Study of interaction of ceruloplasmin, lactoferrin, and myeloperoxidase by photon correlation spectroscopy.

MPO CP

4.06e-06341219916937
Pubmed

Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.

MAPK14 MAPK11

4.06e-06341215304097
Pubmed

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory.

MAPK14 MAPK11

4.06e-06341231273206
Pubmed

The differential regulation of p38α by the neuronal kinase interaction motif protein tyrosine phosphatases, a detailed molecular study.

MAPK14 PTPRR

4.06e-06341223932588
Pubmed

TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α.

MAPK14 MAPK11

4.06e-06341222522454
Pubmed

The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.

MAPK14 MAPK11

4.06e-06341212384504
Pubmed

Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation.

MAPK14 MAPK11

4.06e-06341217855341
Pubmed

Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.

MAPK14 MAPK11

4.06e-06341221715315
Pubmed

Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.

MAPK14 MAPK11

4.06e-06341215273249
Pubmed

Involvement of the p38 mitogen-activated protein kinase alpha, beta, and gamma isoforms in myogenic differentiation.

MAPK14 MAPK11

4.06e-06341218256287
Pubmed

Role of p38 mitogen-activated protein kinase isoforms in murine skin inflammation induced by 12-O-tetradecanoylphorbol 13-acetate.

MAPK14 MAPK11

4.06e-06341221336470
Pubmed

Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.

MAPK14 MAPK11

4.06e-06341211495898
Pubmed

Activin A induction of erythroid differentiation through MKK6-p38alpha/p38beta pathway is inhibited by follistatin.

MAPK14 MAPK11

4.06e-06341220162623
Pubmed

Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK.

MAPK14 CD36

4.06e-06341231746382
Pubmed

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.

MAPK14 MAPK11

4.06e-06341216364914
Pubmed

Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling.

MAPK14 MAPK11

4.06e-06341233605979
Pubmed

Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A.

MAPK14 CD36

4.06e-06341217761940
Pubmed

Protein arginine methyltransferase 1 interacts with and activates p38α to facilitate erythroid differentiation.

MAPK14 MAPK11

4.06e-06341223483889
Pubmed

Correlations between ceruloplasmin, lactoferrin and myeloperoxidase in meconium.

MPO CP

4.06e-06341227903408
Pubmed

Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light.

MAPK14 MAPK11

8.12e-06441215708845
Pubmed

Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions.

MPO PADI4

8.12e-06441233391487
Pubmed

Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.

MAPK14 MAPK11

8.12e-06441220610565
Pubmed

Role for mitogen-activated protein kinase p38 alpha in lung epithelial branching morphogenesis.

MAPK14 MAPK11

8.12e-06441218177852
Pubmed

Identification of core gene in obese type 2 diabetes patients using bioinformatics analysis.

GLUL CD36

8.12e-06441234085602
Pubmed

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.

MAPK14 MAPK11

8.12e-06441210330143
Pubmed

Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.

IFNGR1 PADI4

8.12e-06441224425713
Pubmed

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.

MAPK14 PTPRR

8.12e-06441210601328
Pubmed

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

MAPK14 MAPK11

8.12e-06441217139251
Pubmed

p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice.

MAPK14 MAPK11

8.12e-06441219936205
Pubmed

Cutting edge: IL-4 induces suppressor of cytokine signaling-3 expression in B cells by a mechanism dependent on activation of p38 MAPK.

MAPK14 MAPK11

8.12e-06441215728454
Pubmed

Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.

MAPK14 MAPK11

8.12e-06441220188673
Pubmed

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling.

MAPK14 MAPK11

8.12e-06441224161934
Pubmed

Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines.

MAPK14 MAPK11

8.12e-06441210066767
Pubmed

Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.

MAPK14 MAPK11

8.12e-06441228011639
Pubmed

Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.

MAPK14 MAPK11

8.12e-06441226479921
Pubmed

Effects of paraoxonase, arylesterase, ceruloplasmin, catalase, and myeloperoxidase activities on prognosis in pediatric patients with sepsis.

MPO CP

8.12e-06441228167245
Pubmed

Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2.

MAPK14 MAPK11

8.12e-06441223568773
Pubmed

Differential induction of interleukin-10 in monocytes by HIV-1 clade B and clade C Tat proteins.

MAPK14 MAPK11

8.12e-06441220378550
Pubmed

Bacterial Siderophores Hijack Neutrophil Functions.

MPO PADI4

8.12e-06441228432145
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

GLUL TRHDE PTPRR SUPT5H EPHA2 DHX38

9.41e-0642041628065597
Pubmed

The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest.

MAPK14 MAPK11

1.35e-05541222935704
Pubmed

Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo.

MAPK14 MAPK11

1.35e-05541217074887
Pubmed

Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.

TRHDE PADI4

1.35e-05541221452313
Pubmed

A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.

MAPK14 MAPK11

1.35e-05541217380123
Pubmed

p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes.

MAPK14 MAPK11

1.35e-05541231505169
Pubmed

ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome.

MAPK14 MAPK11

1.35e-05541235857590
Pubmed

Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway.

MAPK14 MAPK11

1.35e-05541212612065
Pubmed

Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly.

MAPK14 MAPK11

1.35e-05541215632108
Pubmed

Peripheral Deletion of CD8 T Cells Requires p38 MAPK in Cross-Presenting Dendritic Cells.

MAPK14 MAPK11

1.35e-05541228864471
Pubmed

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.

MAPK14 MAPK11

1.35e-05541217304211
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

GLUL MPO MAPK14 MAPK11 PTPRM PTPRR SUPT5H EPHA2

1.55e-0597441828675297
Pubmed

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.

MAPK14 MAPK11

2.03e-05641227856911
Pubmed

Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus.

MAPK14 MAPK11

2.03e-05641225754930
Pubmed

Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases.

MAPK14 MAPK11

2.03e-05641215735648
Pubmed

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation.

MAPK14 MAPK11

2.03e-05641222231518
Pubmed

Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.

MAPK14 MAPK11

2.03e-05641214680475
Pubmed

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.

MAPK14 MAPK11

2.84e-05741220551513
Pubmed

Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion.

MPO CD36

2.84e-05741218272685
Pubmed

p38 MAPK signalling cascades: ancient roles and new functions.

MAPK14 MAPK11

2.84e-05741210878576
Pubmed

A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation.

MAPK14 MAPK11

2.84e-05741218678706
Pubmed

A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.

MAPK14 MAPK11

3.78e-05841211359773
Pubmed

F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2.

MAPK14 MAPK11

3.78e-05841234703820
Pubmed

Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.

MAPK14 MAPK11

3.78e-05841212761180
Pubmed

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.

MAPK14 MAPK11

3.78e-0584129155017
Pubmed

Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2.

MAPK14 MAPK11

3.78e-05841211551945
Pubmed

Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.

MAPK14 MAPK11

4.86e-05941223979601
Pubmed

p38-2, a novel mitogen-activated protein kinase with distinct properties.

MAPK14 MAPK11

4.86e-0594129235954
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

MAPK14 PIK3C2G

7.41e-051141216081599
Pubmed

OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc.

MAPK14 EPHA2

7.41e-051141228628118
Pubmed

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.

MAPK14 CD36

8.88e-051241217167049
Pubmed

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.

MAPK14 MAPK11

8.88e-051241212171600
Pubmed

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

MAPK14 MAPK11

1.05e-041341217906618
Pubmed

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

MAPK14 MAPK11

1.22e-04144129687510
Pubmed

gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes.

MAPK14 MAPK11

1.22e-041441212239168
Pubmed

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.

SUPT5H PAFAH1B2

1.22e-041441222354037
Pubmed

PRAK, a novel protein kinase regulated by the p38 MAP kinase.

MAPK14 MAPK11

1.41e-04154129628874
InteractionSLX4IP interactions

IFNGR1 FBXW4 MAPK14 SYNE2

7.28e-0663404int:SLX4IP
InteractionZFP36L1 interactions

MAPK14 PAFAH1B2 KLHL23

2.83e-0530403int:ZFP36L1
InteractionKLHL17 interactions

DOCK1 KLHL12 KLHL23

4.15e-0534403int:KLHL17
Cytoband6q23.3

IFNGR1 IL20RA

2.90e-04284126q23.3
Cytoband2q31.1

PHOSPHO2 KLHL23

2.59e-03844122q31.1
GeneFamilyMitogen-activated protein kinases

MAPK14 MAPK11

1.54e-0413262651
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRM PTPRR

4.11e-0421262813
GeneFamilyFibronectin type III domain containing

ASTN2 PTPRM EPHA2

1.52e-03160263555
GeneFamilyKelch like|BTB domain containing

KLHL12 KLHL23

1.65e-0342262617
GeneFamilySterile alpha motif domain containing

WDSUB1 EPHA2

7.06e-0388262760
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL12 KLHL23

1.58e-02134262861
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

GLUL DOCK1 CP PADI4 PTPRM ABCA9 EPHA2 CD36

1.33e-06438408GSM605850_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

MPO DOCK1 TMEM131 MAPK14 ATRX DHX38 KLHL23

2.43e-05469407Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_1000

MPO DOCK1 IFNGR1 MAPK11 ATRX PTPRM ABCA9 CD36

7.29e-05761408gudmap_developingKidney_e15.5_Endothelial cells_1000
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 TRHDE ASTN2 CFAP54 SYNE2

8.66e-07191415d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFNGR1 CP PTPRR CD36 SYNE2

1.01e-0619741566339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA TMEM131 POMGNT2 EPHA2

1.96e-05174414a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

IFNGR1 IL20RA ABCA9 CD36

2.00e-0517541416849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA TMEM131 POMGNT2 EPHA2

2.05e-05176414d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCelllung|World / shred on tissue and cell subclass

GLUL CP CD36 SYNE2

2.14e-051784147b1e371272328d6b6c3994382d64281ffc737db2
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE GLYATL1 ASTN2 SYNE2

2.38e-051834146878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PIK3C2G ANO3

2.44e-051844142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PIK3C2G ANO3

2.44e-05184414ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PIK3C2G ANO3

2.44e-051844142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH2 STK36 CFAP54 CD36

2.49e-0518541405bc89a566b0db90ae06506e067190a4739a0974
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 CFAP54 SYNE2

2.54e-05186414f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 CFAP54 SYNE2

2.59e-05187414c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRM PTPRR EPHA2 CD36

2.65e-05188414ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRM PTPRR EPHA2 CD36

2.65e-05188414e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRM PTPRR EPHA2 CD36

2.65e-051884140fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE GTF2IRD1 PIK3C2G ABCA9

2.71e-05189414e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell3'_v3-bone_marrow|World / Manually curated celltypes from each tissue

MPO PADI4 ACTR2 SYNE2

2.82e-051914147b759831f1b1c8575c31f67d0d9eb11c6a833cf3
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFNGR1 MAPK11 PTPRM CD36

3.00e-05194414622461e5f9c648252a2f6ec84e7565220a803132
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.18e-05197414ffaf2d7b6aa82008bd64a691b48113626343872c
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

CP EPHA2 SYNE2 NIM1K

3.18e-051974141a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.18e-0519741494e2cc7ec531e58b8ed7e5601fdf8c4bbc3582c8
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.24e-05198414c79c1738560d78b63dbed5f2f9621dbc1c2363cb
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH2 CP CFAP54 ANO3

3.24e-05198414e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.24e-051984141d1c80569f1e307285ba0ebaf5c72e0b5b538864
ToppCellsystemic_lupus_erythematosus-treated-Myeloid|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.24e-05198414f37578f156e8aed2ce30cfa837ae04dd18de05d0
ToppCellsystemic_lupus_erythematosus-flare-Myeloid|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLUL IFNGR1 ACTR2 CD36

3.24e-05198414189346c5eb715f3be427bec3b8e067ababb5b475
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH2 CP CFAP54 ANO3

3.24e-05198414e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-promonocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MPO PADI4 MAPK14 ACTR2

3.24e-05198414ff634a17195d06a8614ed1c6564937d10ca5c00d
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Airway-Club|Control_saline / Treatment groups by lineage, cell group, cell type

CP PIK3C2G ANO3 EPHA2

3.31e-051994145cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GLUL IFNGR1 CP CD36

3.31e-0519941432bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GLUL IFNGR1 CP CD36

3.31e-051994143d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GLUL IFNGR1 CP CD36

3.31e-05199414262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ATRX PTPRM CD36 SYNE2

3.37e-05200414dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFNGR1 CP CD36 SYNE2

3.37e-0520041446dac23d8f9d426fe52ad6dac9c15ce91e615762
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

GLUL IFNGR1 PADI4 CD36

3.37e-05200414621af09aae34226902c03edf556562f3ab35a7d8
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

MPO PADI4 MAPK14 ACTR2

3.37e-05200414cbe667eda1af222467df8bfa157aa22df488f133
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

GLUL IFNGR1 PADI4 CD36

3.37e-05200414b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATRX PTPRM CD36 SYNE2

3.37e-05200414a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellsevere-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MPO PADI4 MAPK14 ACTR2

3.37e-052004145ee43386da8261d2e7602a152e6ba4338d844e08
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MPO PADI4 MAPK14 CD36

3.37e-05200414a3f22826f3d8f917ff0594bdadd93b60763bcaa2
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFNGR1 MAPK11 PTPRM CD36

3.37e-05200414663e2b4672f193844bb9bf4873749114977c19b3
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRHDE ASTN2 ABCA9

2.07e-04125413b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellfacs-Aorta-Heart-3m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO MAPK11 PTPRR

2.43e-04132413dc13b54e38fbda9341972cef11833041f2f2a345
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 PHOSPHO2

2.59e-041354138521107817df49efd9a2e81078c8535ed33e729c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 CFAP54

3.07e-041434137a7a9829ba63468c9745904d9e993590051207ab
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

STK36 CFAP54 PTPRM

3.53e-04150413b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA PADI4 PTPRR

3.67e-04152413d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA PADI4 PTPRR

3.67e-04152413d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STK36 MAPK11 PTPRR

3.81e-04154413e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL PADI4 EPHA2

4.03e-041574134d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL PADI4 EPHA2

4.03e-041574132c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PADI4 ANO3

4.11e-04158413551e3fd7cabc94ba933607ccdcf93f4e799be43a
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PADI4 DHX38

4.26e-04160413984990be02642a562f0c60ea99c01f005e7c02c2
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CP PTPRR EPHA2

4.34e-041614132d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRHDE CP SYNE2

4.34e-041614135fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ASTN2 PHOSPHO2 GTF2IRD1

4.42e-04162413373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IL20RA MAPK11 ANO3

4.50e-04163413218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH2 CFAP54 ANO3

4.58e-04164413e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 SYNE2

4.58e-041644131cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 GTF2IRD1

4.58e-04164413382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO TRHDE ABCA9

4.66e-041654136d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO TRHDE ABCA9

4.66e-0416541384f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CP PTPRR ABCA9

4.74e-0416641360060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CP PTPRR ABCA9

4.74e-04166413ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCellLPS-antiTNF-Epithelial_airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP PTPRR ANO3

4.74e-04166413eb942ed68677e55c46cb039046f45686d4062d7c
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP PTPRR ANO3

4.74e-041664131df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP PTPRR ANO3

4.74e-041664139628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CP PTPRR ABCA9

4.74e-041664134586d6725403f879fc96f67be579022587ce1906
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH2 IFNGR1 CD36

4.91e-04168413e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellfacs-Heart-LV-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO PTPRR CD36

5.00e-041694136a31a940a8474fb087d8fe7193a6974a72e0a014
ToppCellfacs-Heart-LV-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO PTPRR CD36

5.00e-0416941339d627763abd57e53edb1169832b47cfb3e8c274
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP PTPRR ANO3

5.00e-041694138c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP PTPRR ANO3

5.00e-0416941386041be5d3aeab5b9269f7912791b944f325a1b4
ToppCellfacs-Heart-LV-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO PTPRR CD36

5.00e-04169413b85927a256790402e9fc12ebcadd83e4e2afd2ce
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CP ABCA9 ANO3

5.08e-04170413fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPO PADI4 MAPK14

5.08e-04170413cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAPK11 PIK3C2G PTPRR

5.08e-0417041355fe16d98ea284d05fb899888e4569c685644c7b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CP ABCA9 ANO3

5.08e-0417041303044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PIK3C2G ANO3

5.08e-041704133174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

IL20RA CP CFAP54

5.17e-0417141374be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic|GI_small-bowel / Manually curated celltypes from each tissue

GLUL PADI4 CD36

5.17e-04171413098a7fd387357c0d4e1a6169af4d24ef95b30018
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 CFAP54

5.26e-041724130c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ASTN2 CFAP54

5.26e-04172413eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLUL CD36 GALNT4

5.26e-041724130b247fe57163af08132db8df42e6757699885295
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL MPO CD36

5.35e-04173413a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCellILEUM-non-inflamed-(3)_Inf._Macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GLUL PADI4 CD36

5.35e-04173413a8db746992a915a8431ac5c155612e89c4af3cad
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

MPO MAPK14 ACTR2

5.44e-041744131e289b26e2c29dbad15b712a999b96c391a26129
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA TMEM131 POMGNT2

5.44e-041744130fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

GLUL PADI4 CD36

5.44e-0417441305d54a36772f096047521e16a89cc42ae48d2a1d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PIK3C2G ANO3

5.44e-04174413b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PIK3C2G ANO3

5.44e-04174413ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RA TMEM131 POMGNT2

5.44e-04174413b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

IL20RA CP PTPRR

5.44e-041744137d2f802f493f19a068e097b2909a9000e2160266
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

IL20RA ABCA9 CD36

5.53e-041754132eca4c168dea2017ea0e383006e28abed22f32ec
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE PIK3C2G ANO3

5.62e-0417641340993c41c1017b53039a337174fc56632b278609
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CP PHOSPHO2 CD36

5.62e-041764131df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GLYATL1 CP PIK3C2G

5.62e-04176413b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellfacs-Heart-LV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO PTPRR CD36

5.62e-04176413483e36d9bb7268bf179e69a65e1a0be099035162
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL20RA CP PTPRR

5.72e-04177413a4c001a8e44142babf9f24dfe6f7b73a70b11b16
DrugSB 239063

MPO MAPK14 MAPK11

2.77e-0616403CID000005166
DrugL0168

MPO MAPK14 MAPK11

6.54e-0621403CID000445856
DrugSKF86002

MPO MAPK14 MAPK11

9.91e-0624403CID000005228
DrugVX-745

MAPK14 MAPK11 EPHA2

1.12e-0525403CID003038525
DrugAc2-26

MAPK14 MAPK11

1.80e-054402CID000568638
DrugNSC-68458

MAPK14 MAPK11

1.80e-054402CID000249771
Drugdansyl lysine

STK36 CP

1.80e-054402CID000121945
DrugAC1Q6QQG

MPO CP

3.00e-055402CID000124376
Drugtolyltriazole

MAPK14 MAPK11

4.49e-056402CID000025902
DrugAC1NBV4F

MPO CD36

4.49e-056402CID004474233
Drug12-HPETE

MPO MAPK14 MAPK11

5.90e-0543403CID000001415
Drug2,2',4,6-tetrachlorobiphenyl

MAPK14 MAPK11

6.28e-057402CID000044163
DrugCID6325568

MAPK14 MAPK11

6.28e-057402CID006325568
DrugCp-38

MAPK14 MAPK11

6.28e-057402CID006918286
Drugsatratoxin H

MAPK14 MAPK11

6.28e-057402CID000434380
Drug1c88

PADI4 MAPK14 MAPK11 GTF2IRD1

7.00e-05126404CID000444766
DrugCNI-1493

MPO MAPK14 MAPK11

7.72e-0547403CID005745214
DrugZ-D-CH2DCB

MAPK14 MAPK11

8.37e-058402CID009911778
DrugSCH 442416

GLUL MPO

8.37e-058402ctd:C416650
DrugML3403

MAPK14 MAPK11

8.37e-058402CID006419739
DrugABT-491

MPO PAFAH1B2

8.37e-058402CID000154086
Drugbenzenesulfonyl fluoride

MAPK14 MAPK11 PAFAH1B2

8.75e-0549403CID000067779
Drugedaravone

MPO MAPK14 MAPK11

8.75e-0549403CID000004021
Drugmethyl salicylate

GLUL MAPK14 MAPK11

9.87e-0551403CID000004133
DrugSC68376

MAPK14 MAPK11

1.08e-049402CID000005174
DrugSIN-1 chloride

MPO MAPK14 MAPK11

1.11e-0453403CID000065388
Drugheme b

MPO CP PHOSPHO2 MAPK14 MAPK11 KLHL23

1.16e-04444406CID000004973
DrugAC1NOLIT

MAPK14 MAPK11

1.34e-0410402CID005090286
DrugAC1L1CFC

FLII MAPK14 MAPK11

1.45e-0458403CID000001874
Drugnemorosone

MAPK14 MAPK11

1.64e-0411402CID000637105
DrugNarea

GLUL MPO

1.64e-0411402CID000016556
Drugsorafenib

STK36 MAPK14 MAPK11 EPHA2

1.68e-04158404CID000216239
Drugsesamolin

MAPK14 MAPK11

1.96e-0412402CID000101746
DrugMDL-28842

MAPK14 MAPK11

1.96e-0412402CID006441200
DrugAC1NUK3C

STK36 MAPK14 GTF2IRD1

2.03e-0465403CID005481064
Drug1pzj

FLII MAPK14 MAPK11 CD36

2.08e-04167404CID000447976
DrugAllopurinol

GLUL MPO MAPK14

2.13e-0466403ctd:D000493
DrugBIRB796

MAPK14 MAPK11 EPHA2

2.13e-0466403CID000156422
DrugAPDC

MPO CP MAPK14 MAPK11 PIK3C2G

2.27e-04318405CID000065351
DrugM-HT

GLUL MPO STK36

2.53e-0470403CID000001136
DrugSB-242235

MAPK14 MAPK11

2.70e-0414402CID009863367
DrugPyrimidines

MAPK14 MAPK11

2.70e-0414402ctd:D011743
DrugSB202474

MAPK14 MAPK11

2.70e-0414402CID000005162
DrugCPI-1189

MAPK14 MAPK11

2.70e-0414402CID000151118
DrugAC1L9IGO

MPO MAPK14 MAPK11 CD36

3.01e-04184404CID000445722
Drugchromium

MPO CP MAPK14 MAPK11 ANO3

3.05e-04339405CID000023976
Drugnitroxyl

MPO IFNGR1 CP MAPK14

3.07e-04185404CID000000945
DrugAluminum Oxide

MPO ACTR2 CD36

3.11e-0475403ctd:D000537
DrugH088

IL20RA FLII CP

3.11e-0475403CID000004542
DrugAC1L1GKN

STK36 MAPK14

3.11e-0415402CID000003726
DrugMMP-2 Inhibitor I

MAPK14 MAPK11

3.11e-0415402CID000004220
DrugDiflunisal [22494-42-4]; Down 200; 16uM; HL60; HG-U133A

GLUL FBXW4 PADI4 DHX38

3.39e-041904041990_DN
DrugAEBSF

MAPK14 MAPK11 PIK3C2G PAFAH1B2

3.46e-04191404CID000001701
DrugSD-282

MAPK14 MAPK11

3.56e-0416402CID014973220
DrugAMP 579

MAPK14 MAPK11

3.56e-0416402CID006918429
DrugL-anserine

MPO CP

3.56e-0416402CID000011444
Drugp-nitrophenyl phosphate

MAPK14 MAPK11 PTPRM PTPRR

3.67e-04194404CID000000378
DrugAGEPC

GLUL MPO MAPK14 MAPK11 PAFAH1B2

3.81e-04356405CID000461545
DrugRetinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

MPO MAPK14 MAPK11 PAFAH1B2

3.89e-041974043165_DN
DrugLidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A

ASTN2 MAPK14 MAPK11 ATRX

3.97e-041984041499_UP
DrugAmbotz208527-57-5

MAPK14 MAPK11

4.03e-0417402CID010258704
Drugdracorhodin

MAPK14 MAPK11

4.03e-0417402CID000069509
Drugkazinol B

MAPK14 MAPK11

4.03e-0417402CID000480869
DrugAmifostine

MPO MAPK14

4.03e-0417402ctd:D004999
Druguric acid

MPO CP MAPK14 MAPK11

4.05e-04199404CID000001175
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

DOCK1 FLII DHX38 PAFAH1B2

4.05e-041994046963_DN
DrugEsculetin [305-01-1]; Down 200; 22.4uM; MCF7; HT_HG-U133A

MAPK14 ATRX EPHA2 PAFAH1B2

4.12e-042004047459_DN
Drugcariporide

MPO MAPK14 MAPK11

4.65e-0486403CID000151172
DrugC11102

MAPK14 MAPK11 PTPRR

4.65e-0486403CID000443069
DrugOxpl

CD36 PAFAH1B2

5.05e-0419402CID000194296
Drugalpha-ketoisovalerate

MAPK14 MAPK11 GTF2IRD1

5.14e-0489403CID000000049
DrugHemin

MPO MAPK14 MAPK11

5.31e-0490403ctd:D006427
DrugPyrazoles

MAPK14 MAPK11

5.60e-0420402ctd:D011720
Drug5-chlorouracil

MPO STK36

5.60e-0420402CID000015758
Drugcompound 9b

MAPK14 MAPK11

5.60e-0420402CID000207510
DrugAC1OCF3N

MPO PAFAH1B2

5.60e-0420402CID006918166
Drugn-sulfo-2-aminotricarballylate

MAPK14 MAPK11

5.60e-0420402CID000135808
DrugSB 203580

GLUL MPO CP MAPK14 MAPK11

5.64e-04388405ctd:C093642
Drugoleoyl-lysophosphatidic acid

DOCK1 MAPK14 MAPK11 PTPRM PIK3C2G

5.84e-04391405CID000003987
Drugneurokinin-1 receptor antagonist

MPO FLII

6.19e-0421402CID001122655
DrugCaffeic Acid-13C3

MPO MAPK14 MAPK11

6.22e-0495403CID000002518
DrugAG126

MPO MAPK14 MAPK11

6.41e-0496403CID000002046
Drugtelmisartan

MPO MAPK14 CD36

6.61e-0497403ctd:C084178
Drugrifaximin

MPO CD36

6.80e-0422402ctd:C042734
DrugAC1L1BHQ

MPO MAPK14 MAPK11 CD36

6.97e-04230404CID000001444
DrugBN 50739

MPO PAFAH1B2

7.44e-0423402CID000115002
Drug3,5,6-trichloro-2-pyridinol

MAPK14 MAPK11

7.44e-0423402CID000023017
Drugtyrphostin B46

MAPK14 MAPK11

7.44e-0423402CID000002058
DrugAC1L1K7T

STK36 MAPK14 MAPK11 PIK3C2G CD36 DHX38

7.68e-04632406CID000005376
Drugepicholesterol

CP MAPK14 MAPK11 ABCA9 CD36 PAFAH1B2

7.93e-04636406CID000000304
Druglariat

MPO WDSUB1 DHX38

8.32e-04105403CID000165706
Drugtrinexapac-ethyl

STK36 CP

8.80e-0425402CID000092421
DrugHypertensin II

MPO FLII MAPK14 MAPK11 PIK3C2G

8.87e-04429405CID000025476
DrugFructose

GLUL CP PIK3C2G CD36

8.95e-04246404ctd:D005632
Drugnorethisterone oenanthate

MPO FLII WDSUB1

9.27e-04109403CID000019688
DrugAC1NSK9Q

MAPK14 MAPK11

9.52e-0426402CID005311233
DrugCAS 83919-23-7

MAPK14 MAPK11

9.52e-0426402CID000004240
Drugadenosine kinase inhibitor

PHOSPHO2 KLHL23

9.52e-0426402CID000001973
Drug6-OHDA

MPO FLII MAPK14 MAPK11

1.02e-03255404CID000004624
Drugfluperlapine

MPO FLII

1.03e-0327402CID000049381
Diseasecyclic adenosine monophosphate measurement

PTPRM CD36

2.29e-0417392EFO_0010473
Diseaseglucose homeostasis measurement, acute insulin response measurement

ASTN2 PTPRM

2.57e-0418392EFO_0006831, EFO_0006896
Diseaseosteoporosis (implicated_via_orthology)

IFNGR1 MAPK14

2.87e-0419392DOID:11476 (implicated_via_orthology)
DiseaseBrain Diseases

MPO CP

5.01e-0425392C0006111
DiseaseEncephalopathies

MPO CP

5.85e-0427392C0085584
Diseasearteriosclerosis (is_marker_for)

IFNGR1 CD36

6.76e-0429392DOID:2349 (is_marker_for)
Diseaselevel of Sphingomyelin (d38:1) in blood serum

FBXW4 SYNE2

7.23e-0430392OBA_2045180
DiseaseCholestasis, Extrahepatic

MPO MAPK14

8.23e-0432392C0005398
DiseaseArthritis, Experimental

MPO CP

1.29e-0340392C0993582
DiseaseArthritis, Adjuvant-Induced

MPO CP

1.29e-0340392C0003865
DiseaseArthritis, Collagen-Induced

MPO CP

1.29e-0340392C0971858

Protein segments in the cluster

PeptideGeneStartEntry
EVMDQWTLQMGYPVI

TRHDE

586

Q9UKU6
EEMPWRAQMNLYLAG

CFAP54

1476

Q96N23
MDPEGQQQMWQVIRA

ABCA9

1451

Q8IUA7
NYPMENGIVRNWDDM

ACTR2

71

P61160
DEAMGYPMVQQWRVR

ASTN2

846

O75129
WNLQPMNLHGLMDEY

ANO3

741

Q9BYT9
NIWLQEGLDMQMIIY

PIK3C2G

941

O75747
LFDAYMVAQNPGEWM

CP

321

P00450
VGDEVNWYLMGMGNE

CP

976

P00450
QWMQDEMEIGYIQAP

PADI4

346

Q9UM07
PEIMLNWMHYNQTVD

MAPK11

191

Q15759
MLLDNGQEVYMWVGT

FLII

1196

Q13045
PEIMLNWMHYNQTVD

MAPK14

191

Q16539
MEQYGTPNNIDIWMG

MPO

631

P05164
NMEVLVDSWPEYQMV

GLYATL1

41

Q969I3
AMLPGMDLQYVAWRN

POMGNT2

381

Q8NAT1
IDCIMNDEWMQGVPY

NIM1K

316

Q8IY84
MSQNLEPMEYSVVVW

PHOSPHO2

211

Q8TCD6
PGENETYLMQFMEEW

IL20RA

531

Q9UHF4
QGPMINTVDDFWQMV

PTPRR

466

Q15256
SYMLQRWQEDGGVMI

ATRX

1666

P46100
MERYDPNIDQWSMLG

KLHL12

396

Q53G59
YDPEQNEWREIAPMM

KLHL23

481

Q8NBE8
IGKNVYPFDWVIMNM

DOCK1

976

Q14185
YPFDWVIMNMVQNKV

DOCK1

981

Q14185
WIFDVQNPQEVMMNS

CD36

66

P16671
WNTFEFYMQIGEPMI

GALNT4

261

Q8N4A0
GWDLMQNIMNDMPIY

EPHA2

51

P29317
NMEVLVDSWPEYQMV

GLYATL1B

41

A0A0U1RQE8
MPWMQLEDDSLYISQ

FBXW4

121

P57775
GEMWQVVDMAQQEED

LLCFC1

61

Q96L11
ANQISLVQWPMYMVD

GTF2IRD1

931

Q9UHL9
KNDGPEIQQQWMLYM

DNAH2

811

Q9P225
NMNPIVYWEYQIMPQ

IFNGR1

41

P15260
GDSMVQLMQQYEIWR

PAFAH1B2

46

P68402
TQGPMQETIYDFWRM

PTPRM

971

P28827
NQHPWFGMEQEYTLM

GLUL

126

P15104
EQDPGQAQEWMDNLM

SYNE2

3746

Q8WXH0
RLGYWNQQMVPIKEM

SUPT5H

246

O00267
GQQGVTFDLQPMEWM

STK36

811

Q9NRP7
VQPGVAMQEDMWDAD

TMEM131

766

Q92545
PEDNMLNSMYQLWIL

DHX38

916

Q92620
WNTENGQMLAVMEQP

WDSUB1

81

Q8N9V3