Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentprocentriole

CEP192 CEP152

7.05e-0531022GO:0120098
GeneOntologyCellularComponentanchoring junction

FLT1 SORBS2 RTN4 TRPC6 SORBS1 ACTN1 TRIM29 ITGB4 CDH22 LMO7 TJP1 SVIL NECTIN4 WNK3 PDZD2

7.62e-0597610215GO:0070161
GeneOntologyCellularComponentadherens junction

SORBS1 TRIM29 CDH22 LMO7 TJP1 NECTIN4 WNK3

8.17e-052121027GO:0005912
GeneOntologyCellularComponentpericentriolar material

CEP85 CEP192 CEP152

3.38e-04281023GO:0000242
GeneOntologyCellularComponentprocentriole replication complex

CEP192 CEP152

3.49e-0461022GO:0120099
GeneOntologyCellularComponentcell-cell junction

TRPC6 SORBS1 ACTN1 TRIM29 CDH22 LMO7 TJP1 NECTIN4 WNK3 PDZD2

6.25e-0459110210GO:0005911
DomainSOHO

SORBS2 SORBS1

8.15e-053982PS50831
DomainSorb

SORBS2 SORBS1

8.15e-053982SM00459
DomainSorb

SORBS2 SORBS1

8.15e-053982PF02208
DomainSoHo_dom

SORBS2 SORBS1

8.15e-053982IPR003127
PathwayKEGG_ADHERENS_JUNCTION

SORBS1 ACTN1 CREBBP LMO7 TJP1 NECTIN4

3.23e-0673796M638
Pubmed

Human transcription factor protein interaction networks.

CEP85 FOS PSMA2 PSMB4 PHF6 ZC3H18 CEP192 UPF1 CREBBP NUP205 PRDM1 NFIA RFXANK SVIL RLIM NCOA1 CEP152 FOXC1

1.71e-0714291021835140242
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SORBS2 SPIRE1 SORBS1 CEP192 TMCC3 SLC38A2 SBF1 LMO7 TJP1 SVIL NAV2 CEP152 IRS2 WNK3

2.32e-078611021436931259
Pubmed

Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.

FOS CREBBP NCOA1

4.87e-076102310497212
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SORBS2 CEP85 PPP1R9A SORBS1 CEP192 LMO7 TJP1 CEP152 IRS2 PRKDC

8.10e-074461021024255178
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

ACTN1 SLC38A2 LMO7 TJP1 SVIL PRKDC

1.39e-06118102627377895
Pubmed

Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8(+) T suppressor cells.

FOS DUSP10 LILRB4

2.03e-069102322387553
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

SORBS2 SORBS1 CACHD1 FOXJ3 CEP152 PDZD2

2.44e-06130102612421765
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

LEMD3 NUP205 GUCY2D PRKDC PDZD2

3.28e-0677102524927568
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RTN4 SPIRE1 CACHD1 FOXJ3 NUP205 SLC38A2 SBF1 LMO7 NAV2 NBR1

3.71e-065291021014621295
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

FOS RTN4 FOXJ3 CREBBP HOXA1 MEOX2 HOXB5 NFIA LMO7 NCOA1 PLXNA1

7.76e-067091021122988430
Pubmed

Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.

CACHD1 MDGA1

8.52e-062102231908000
Pubmed

Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.

TAS1R3 PUSL1

8.52e-062102211326277
Pubmed

The soluble nectin-4 ecto-domain promotes breast cancer induced angiogenesis via endothelial Integrin-β4.

ITGB4 NECTIN4

8.52e-062102230056265
Pubmed

Different developmental arrest points in RAG-2 -/- and SCID thymocytes on two genetic backgrounds: developmental choices and cell death mechanisms before TCR gene rearrangement.

RAG2 PRKDC

8.52e-06210229126963
Pubmed

Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.

FLT1 PRKDC

8.52e-062102228377452
Pubmed

Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.

RBFOX1 WNK3

8.52e-062102223027929
Pubmed

Cardiovascular adaptations of pregnancy in T and B cell-deficient mice.

RAG2 PRKDC

8.52e-062102221613629
Pubmed

Recombination activation gene-2-deficient blastocyst complementation analysis reveals an essential role for nuclear factor I-A transcription factor in T-cell activation.

RAG2 NFIA

8.52e-062102221602176
Pubmed

Dendritic cells require T cells for functional maturation in vivo.

RAG2 PRKDC

8.52e-062102210591187
Pubmed

Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina.

RAG2 PRKDC

8.52e-062102223203926
Pubmed

c-fos overexpression in splenic B cells augments development of marginal zone B cells.

RAG2 FOS

8.52e-062102215607821
Pubmed

T cell receptor gamma and delta gene rearrangements in scid thymocytes. Similarity to those in normal thymocytes.

RAG2 PRKDC

8.52e-06210221661315
Pubmed

Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS.

FOS NECTIN4

8.52e-062102238063270
Pubmed

The NCOA1-CBP-NF-κB transcriptional complex induces inflammation response and triggers endotoxin-induced myocardial dysfunction.

CREBBP NCOA1

8.52e-062102235339471
Pubmed

Arg kinase-binding protein 2 (ArgBP2) interaction with α-actinin and actin stress fibers inhibits cell migration.

SORBS2 ACTN1

8.52e-062102225429109
Pubmed

Distinct roles of Cep192 and Cep152 in acentriolar MTOCs and spindle formation during mouse oocyte maturation.

CEP192 CEP152

8.52e-062102228970258
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ELOA CEP85 LEMD3 PPP1R9A CEP192 CACHD1 PHKA1 SBF1 TJP1 SVIL DUSP10 NBR1 FOXC1

1.24e-0510491021327880917
Pubmed

AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.

FLT1 TJP1 FOXC1

1.33e-0516102326968737
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

FLT1 SGSM1 FOXJ3 USP21 LMO7 TJP1 SVIL NBR1

1.43e-05371102815747579
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

ARHGAP42 SORBS2 LEMD3 AHDC1 SBF1 LMO7 TJP1 HEATR5B

1.63e-05378102834315543
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CEP85 CEP192 TJP1 SVIL CEP152 NBR1

1.79e-05184102632908313
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

PRDM1 MEOX2 HOXB5 FOXB1 NFIA BARHL2

2.20e-05191102624146773
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

PSMA2 PSMB4 LMO7 TJP1 SVIL PRKDC

2.48e-05195102617110338
Pubmed

Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.

MUC16 NBR1

2.55e-053102214676194
Pubmed

Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection.

RAG2 PRKDC

2.55e-053102222665378
Pubmed

Cereblon inhibits proteasome activity by binding to the 20S core proteasome subunit beta type 4.

PSMA2 PSMB4

2.55e-053102223026050
Pubmed

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5.

RAG2 FOS

2.55e-053102210524622
Pubmed

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.

CEP192 CEP152

2.55e-053102223641073
Pubmed

Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene.

CREBBP NCOA1

2.55e-053102210848596
Pubmed

CREB, AP-1, ternary complex factors and MAP kinases connect transient receptor potential melastatin-3 (TRPM3) channel stimulation with increased c-Fos expression.

FOS TRPM3

2.55e-053102226493679
Pubmed

[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2].

SORBS2 SORBS1

2.55e-053102212510380
Pubmed

Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies.

RAG2 PRKDC

2.55e-053102227197263
Pubmed

Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1).

CREBBP NCOA1

2.55e-053102211713256
Pubmed

Reversal of malignant ADAR1 splice isoform switching with Rebecsinib.

RAG2 PRKDC

2.55e-053102236803553
Pubmed

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

FOS CREBBP

2.55e-053102210487758
Pubmed

Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits.

FOS NCOA1

2.55e-05310229642216
Pubmed

Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer.

MEOX2 PRKDC

2.55e-053102237729060
Pubmed

Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton.

SORBS2 ACTN1

2.55e-053102216125169
Pubmed

Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.

CREBBP NCOA1

2.55e-053102211574547
Pubmed

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

RAG2 PRKDC

2.55e-05310228885865
Pubmed

Resistance to skin tumorigenesis in DNAPK-deficient SCID mice is not due to immunodeficiency but results from hypersensitivity to TPA-induced apoptosis.

RAG2 PRKDC

2.55e-053102210545405
Pubmed

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

RAG2 PRKDC

2.55e-053102212559174
Pubmed

LMO7 Is a Negative Feedback Regulator of Transforming Growth Factor β Signaling and Fibrosis.

FOS LMO7

2.55e-053102230586711
Pubmed

CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription.

CREBBP NFIA

2.55e-053102210085123
Pubmed

HOXB5 cooperates with NKX2-1 in the transcription of human RET.

RET HOXB5

2.55e-053102221677782
Pubmed

Differences between immunodeficient mice generated by classical gene targeting and CRISPR/Cas9-mediated gene knockout.

RAG2 PRKDC

2.55e-053102229594927
Pubmed

Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies.

PRDM1 CRYBG1

2.55e-053102219194464
Pubmed

High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4.

TAS1R3 PUSL1

2.55e-053102211178737
Pubmed

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.

CEP192 CEP152

2.55e-053102224277814
Pubmed

Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rγnull mice display a T-effector memory phenotype.

RAG2 PRKDC

2.55e-053102222937164
Pubmed

The impact of modifier genes on cone-rod dystrophy heterogeneity: An explorative familial pilot study and a hypothesis on neurotransmission impairment.

CACNG8 GUCY2D

2.55e-053102236490268
Pubmed

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

PRKDC POLQ

2.55e-053102216520097
Pubmed

Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival.

FOS PRDM1

2.55e-053102218725523
Pubmed

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.

PRDM1 MEOX2

2.55e-053102226779602
Pubmed

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

RAG2 PRKDC

2.55e-05310228769647
Pubmed

B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.

RAG2 PRKDC

2.55e-053102232938796
Pubmed

Ablation of Ezh2 in neural crest cells leads to aberrant enteric nervous system development in mice.

RET HOXA1 HOXB5

2.69e-0520102330169530
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CEP85 LEMD3 PSMA2 RTN4 PSMB4 PUSL1 NUP205 SBF1 TJP1 IRS2 DUSP10 PRKDC

2.91e-059741021228675297
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

SORBS1 PHKA1 SVIL RBFOX1

3.00e-0560102419075228
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

FLT1 ABCA13 MUC16 TMCC3 GUCY2C LMO7 TJP1 NAV2 CRYBG1

3.71e-05552102910737800
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

PPP1R9A UPF1 NUP205 TJP1 PRKDC

3.91e-05128102523858473
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOS PSMB4 PUSL1 TRIM29 FOXJ3 CREBBP NUP205 FOXB1 NFIA NBR1 FOXC1

4.43e-058571021125609649
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

RTN4 SORBS1 TRIM29 LMO7 TJP1 SVIL NAV2 NECTIN4 CRYBG1

4.44e-05565102925468996
Pubmed

FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner.

NFIA FOXC1

5.09e-054102215684392
Pubmed

Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53.

CREBBP NCOA1

5.09e-054102210551785
Pubmed

FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes.

ITGB4 TJP1

5.09e-054102223977053
Pubmed

Dendritic cell-dependent in vivo generation of autoregulatory T cells by antidiabetogenic MHC class II.

RAG2 PRKDC

5.09e-054102223740949
Pubmed

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.

RAG2 PRKDC

5.09e-054102210202929
Pubmed

Anti-CD20 antibody therapy and susceptibility to Pneumocystis pneumonia.

RAG2 PRKDC

5.09e-054102225733518
Pubmed

Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.

CREBBP NCOA1

5.09e-054102212208951
Pubmed

JunB is a gatekeeper for B-lymphoid leukemia.

RAG2 MEOX2

5.09e-054102217297445
Pubmed

Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.

FOS RET

5.09e-054102217209045
Pubmed

The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.

CREBBP NCOA1

5.09e-054102211463834
Pubmed

Early thymocyte development is regulated by modulation of E2A protein activity.

RAG2 PRKDC

5.09e-054102211560990
Pubmed

Possible involvement of glial cell line-derived neurotrophic factor and its receptor, GFRalpha1, in survival and maturation of thymocytes.

RAG2 RET

5.09e-054102212884298
Pubmed

Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in mice.

RET HOXB5

5.09e-054102218395091
Pubmed

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1.

CREBBP NCOA1

5.09e-054102211113179
Pubmed

Rag-dependent and Rag-independent mechanisms of Notch1 rearrangement in thymic lymphomas of Atm(-/-) and scid mice.

RAG2 PRKDC

5.09e-054102219000702
Pubmed

Homeostatic regulation of intestinal villous epithelia by B lymphocytes.

RAG2 PRKDC

5.09e-054102211884426
Pubmed

Creation of "humanized" mice to study human immunity.

RAG2 PRKDC

5.09e-054102218491294
Pubmed

Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice.

RAG2 PRKDC

5.09e-054102212438215
Pubmed

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.

CREBBP NCOA1

5.09e-054102210339548
Pubmed

Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome.

PSMA2 PSMB4

5.09e-054102215660529
Pubmed

Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.

PRDM1 PRKDC

5.09e-054102227941793
Pubmed

Activation of PPARgamma coactivator-1 through transcription factor docking.

CREBBP NCOA1

5.09e-054102210558993
Pubmed

Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

RAG2 PRKDC

5.09e-054102219362533
Pubmed

β4 Integrin signaling induces expansion of prostate tumor progenitors.

ITGB4 PRKDC

5.09e-054102223348745
Pubmed

A signature motif in transcriptional co-activators mediates binding to nuclear receptors.

CREBBP NCOA1

5.09e-05410229192902
Pubmed

Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations.

CREBBP NCOA1

5.09e-05410229556555
Pubmed

Hirschsprung's disease and variants in genes that regulate enteric neural crest cell proliferation, migration and differentiation.

RET HOXB5

5.09e-054102222648184
InteractionCNTRL interactions

SORBS1 CEP192 UPF1 CREBBP NUP205 LMO7 TJP1 CEP152

4.98e-06193998int:CNTRL
InteractionAFDN interactions

SORBS2 PPP1R9A SORBS1 CEP192 SOCS6 USP21 SLC38A2 TJP1 NECTIN4 CEP152

5.62e-063339910int:AFDN
InteractionYWHAH interactions

SORBS2 SPIRE1 SORBS1 CEP192 SOCS6 CREBBP TMCC3 USP21 SLC38A2 SBF1 LMO7 TJP1 SVIL NAV2 NCOA1 CEP152 IRS2 WNK3

6.20e-0611029918int:YWHAH
InteractionDYNLT5 interactions

PPP1R9A MEOX2 SVIL

1.35e-0510993int:DYNLT5
InteractionVASP interactions

SORBS1 CEP192 ACTN1 LMO7 TJP1 SVIL CEP152 IRS2 NBR1

1.45e-05294999int:VASP
InteractionFBF1 interactions

CEP85 SORBS1 CEP192 TRIM29 MEOX2 TJP1 ACCS

2.16e-05171997int:FBF1
InteractionAMOT interactions

CEP85 CEP192 SOCS6 HOXA1 MEOX2 TJP1 RLIM CEP152 NBR1

2.33e-05312999int:AMOT
InteractionSFN interactions

SORBS2 SPIRE1 ZC3H18 SORBS1 CEP192 ACTN1 TMCC3 NFIA LMO7 TJP1 SVIL NAV2 IRS2

3.37e-056929913int:SFN
InteractionZYX interactions

SORBS1 CEP192 ACTN1 LMO7 TJP1 SVIL CEP152 NBR1 WNK3

3.52e-05329999int:ZYX
InteractionNRXN1 interactions

ELOA RTN4 ACTN1 TRIM29 PRKDC PDZD2

3.86e-05127996int:NRXN1
InteractionLZTS2 interactions

ELOA SORBS2 CEP85 SORBS1 CEP192 TRIM29 FAM90A1 SBF1 TJP1 RBFOX1 CEP152

4.29e-055129911int:LZTS2
InteractionHOXD13 interactions

TAS1R3 FOS CREBBP FOXB1 FOXC1

5.23e-0582995int:HOXD13
InteractionTERF1 interactions

CEP85 PSMA2 RTN4 ZC3H18 ACTN1 FOXJ3 FBXO4 RLIM PRKDC

5.32e-05347999int:TERF1
InteractionPBX1 interactions

FAM90A1 CREBBP HOXA1 HOXB5 FOXC1

6.21e-0585995int:PBX1
InteractionNFIC interactions

ELOA FOS CREBBP PRDM1 NFIA RLIM FOXC1

7.99e-05210997int:NFIC
InteractionCDH1 interactions

RTN4 SORBS1 ACTN1 UPF1 TRIM29 CREBBP LMO7 TJP1 SVIL NAV2 NECTIN4 CRYBG1 PRKDC

9.73e-057689913int:CDH1
InteractionYWHAQ interactions

SORBS2 SPIRE1 SORBS1 CEP192 UPF1 SOCS6 ITGB4 TMCC3 SBF1 LMO7 TJP1 SVIL NAV2 NCOA1 IRS2 PRKDC

1.05e-0411189916int:YWHAQ
InteractionODF2 interactions

CEP85 CEP192 MEOX2 LMO7 TJP1 SVIL

1.30e-04158996int:ODF2
InteractionACTR3 interactions

FOS SORBS1 CEP192 ACTN1 SOCS6 TJP1 RLIM CEP152

1.30e-04305998int:ACTR3
InteractionADAMTSL2 interactions

HOXA1 ADAMTSL2

1.42e-044992int:ADAMTSL2
InteractionVIM interactions

CEP85 PSMA2 ZC3H18 SORBS1 ACTN1 TRIM29 ITGB4 LMO7 TJP1 SVIL RLIM CRYBG1 PRKDC

1.53e-048049913int:VIM
GeneFamilyGuanylate cyclase receptors

GUCY2C GUCY2D

3.71e-047772343
GeneFamilyForkhead boxes

FOXJ3 FOXB1 FOXC1

8.11e-0443773508
GeneFamilyHOXL subclass homeoboxes

HOXA1 MEOX2 HOXB5

1.41e-0352773518
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP NCOA1

2.34e-0317772486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP NBR1

2.62e-031877291
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

FLT1 SORBS2 FOS NFIA TJP1 SVIL NCOA1

9.11e-07137997M39241
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORBS2 ABCA13 MUC16 TRIM29 NFIA LMO7 TJP1 NECTIN4 FUT3

6.95e-101981009a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORBS2 ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 NECTIN4 FOXC1

7.59e-102001009ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

SORBS2 MUC16 RET ITGB4 TJP1 NAV2 WNK3 PDZD2

1.07e-081881008a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORBS2 ABCA13 MUC16 TRIM29 NFIA LMO7 TJP1 NECTIN4

1.67e-081991008b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SORBS2 ABCA13 TRIM29 ITGB4 LMO7 TJP1 NECTIN4 FOXC1

1.74e-08200100897f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORBS2 ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 NECTIN4

1.74e-082001008d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCA13 MUC16 TRIM29 ITGB4 NECTIN4 FUT3 PLXNA1

1.36e-0717410079e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 TRPC6 RET PRDM1 TRPM3 SVIL DUSP10

1.77e-071811007af92b8b7f455210dab502ef6964f3a0162180759
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ARHGAP42 PPP1R9A SPIRE1 CACHD1 LMO7 SVIL NAV2

1.77e-071811007c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 TRPC6 RET PRDM1 TRPM3 SVIL DUSP10

1.84e-071821007d4cb23b5a974c096a0ce84b47fe351eef44894d7
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 COL6A3 FOS TRPC6 GPR63 TJP1 RBFOX1

2.21e-071871007fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

SORBS2 PPP1R9A SORBS1 LMO7 SVIL RBFOX1 PDZD2

2.84e-071941007c3535f7cc0076653c72db582047cff053c322397
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.04e-0719610073e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.04e-0719610071efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.15e-0719710075ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.15e-07197100708b371309cd790b171ed76cabc7d910e71cd2835
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 COL6A3 FOS ACTN1 HOXB5 RBFOX1 DUSP10

3.15e-071971007b1135378d768fbbe62a75747d1e8653d35252187
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.15e-0719710079f49feee38647bbf964974aac96fa75602186b5c
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 TRIM29 ITGB4 LMO7 TJP1 NECTIN4 FUT3

3.37e-071991007d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellNS-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 MUC16 TRIM29 NFIA LMO7 TJP1 NECTIN4

3.37e-071991007d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MUC16 TRIM29 ITGB4 LMO7 TJP1 NECTIN4 FUT3

3.37e-0719910072a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 TRIM29 ITGB4 LMO7 TJP1 NECTIN4 FUT3

3.37e-071991007fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellcontrol-Epithelial|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SORBS2 ABCA13 MUC16 TRIM29 LMO7 TJP1 NECTIN4

3.48e-072001007f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 TRPC6 RET PRDM1 TRPM3 SVIL DUSP10

3.48e-0720010078c1d4fffa5abe89ee2ff84fed2dfa97c779bde04
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 TRPC6 RET PRDM1 TRPM3 SVIL DUSP10

3.48e-0720010071026b4ede4ea61d01ea942164b37a08c8c8234ff
ToppCellSevere-Epithelial-Epithelial-|Severe / Condition, Lineage, Cell class and cell subclass

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.48e-0720010078669ce08f93eefb8ac970e30cdc4b1f908023c54
ToppCellSevere-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.48e-0720010076ead9db88568bb829d564a6d8e85f71fd765bac0
ToppCellSevere-Epithelial-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ABCA13 MUC16 TRIM29 ITGB4 LMO7 TJP1 FUT3

3.48e-0720010073bd1ce2793651c9badd69f011d2531183594e5f4
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 TRPC6 RET PRDM1 TRPM3 SVIL DUSP10

3.48e-07200100772c9cd872074b60f62685a95eab83c41e609eb6e
ToppCellControl|World / group, cell type (main and fine annotations)

SORBS2 FOS PPP1R9A LMO7 NAV2 PDZD2

2.21e-061681006a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MUC16 TRIM29 ITGB4 NECTIN4 FUT3 FOXC1

2.89e-0617610068d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 SORBS1 SLC38A2 NFIA NAV2 ADAMTSL2

3.09e-061781006d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

ARHGAP42 TRPC6 CACHD1 TRIM29 ITGB4 LMO7

3.40e-0618110066d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOS SORBS1 ACTN1 TRIM29 SVIL IRS2

3.51e-06182100637547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CEP85 PSMB4 CACHD1 TRIM29 LRRC27 ATG4D

3.51e-0618210063fddadb2ff75013ec6eeb415872667a6bae1da2d
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

ARHGAP42 TRPC6 CACHD1 TRIM29 ITGB4 LMO7

3.62e-0618310060f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

SORBS2 SORBS1 LMO7 SVIL RBFOX1 PDZD2

3.74e-061841006ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIRE1 TRIM29 FOXJ3 SLC38A2 RLIM IRS2

3.85e-061851006eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 SGSM1 SPIRE1 ITGB4 HOXA1 FOXC1

3.98e-061861006c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

ARHGAP42 PPP1R9A CACHD1 LMO7 TJP1 NAV2

3.98e-0618610069798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

COL6A3 TRPC6 MEOX2 SLC38A2 NAV2 ADAMTSL2

4.10e-06187100692d468dde81125d51daf7abd4703741abe1ab91c
ToppCelldroplet-Fat-Scat-21m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.23e-0618810068671fdbc4138e6f9559920779c98628ed80f0da3
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

SORBS2 SORBS1 LMO7 SVIL RBFOX1 PDZD2

4.36e-0618910065e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-061901006da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-061901006d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-0619010063395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-061901006dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-061901006c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-061901006e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-0619010065174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

SORBS2 SORBS1 LMO7 SVIL RBFOX1 PDZD2

4.49e-061901006fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS1 TMCC3 MEOX2 LMO7 TJP1

4.49e-06190100690e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

SORBS2 SORBS1 LMO7 SVIL RBFOX1 PDZD2

4.63e-06191100625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SORBS2 PPP1R9A CACHD1 LMO7 NAV2 PDZD2

4.77e-061921006499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

ARHGAP42 PPP1R9A CACHD1 LMO7 TJP1 NAV2

4.77e-061921006d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SORBS2 PPP1R9A CACHD1 LMO7 NAV2 PDZD2

4.77e-061921006efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS2 ITGB4 TMCC3 TJP1 FOXC1

4.92e-06193100654024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS2 ITGB4 TMCC3 TJP1 FOXC1

4.92e-06193100681d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SORBS2 PPP1R9A SORBS1 LMO7 SVIL RBFOX1

4.92e-061931006dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 COL6A3 ACTN1 HOXB5 SVIL ADAMTSL2

4.92e-0619310063316d6a39abb6a518d45b846254325fc7a8b2035
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT1 TRPC6 TMCC3 PRDM1 NAV2 DUSP10

4.92e-0619310068b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

FLT1 SLC17A3 FOS ACTN1 ITGB4 FOXC1

5.06e-061941006b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellNS-critical-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRIM29 LMO7 TJP1 NECTIN4 FUT3 FOXC1

5.06e-061941006614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP42 TRPC6 ACTN1 NFIA PLXNA1 PDZD2

5.06e-061941006aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

SORBS2 PPP1R9A SORBS1 LMO7 SVIL RBFOX1

5.22e-061951006f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

SORBS2 PPP1R9A SORBS1 LMO7 SVIL RBFOX1

5.22e-06195100675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

FLT1 FOS TMCC3 TJP1 SVIL PDZD2

5.22e-0619510066b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

COL6A3 TRPC6 MEOX2 SLC38A2 NAV2 ADAMTSL2

5.22e-061951006aa0add081881d349099d12efca5cdee098038d4e
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS2 SORBS1 TMCC3 MEOX2 LMO7

5.37e-061961006b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS2 SORBS1 TMCC3 MEOX2 LMO7

5.37e-061961006ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SORBS2 SORBS1 TMCC3 MEOX2 LMO7

5.37e-061961006039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 SORBS1 ACTN1 SLC38A2 NFIA ADAMTSL2

5.37e-0619610063a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 SORBS1 ACTN1 SLC38A2 NFIA ADAMTSL2

5.37e-061961006bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 FOS ACTN1 HOXB5 RBFOX1 DUSP10

5.53e-061971006378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 SORBS1 ACTN1 NFIA NAV2 ADAMTSL2

5.53e-06197100685a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 SORBS1 ACTN1 NFIA NAV2 ADAMTSL2

5.53e-061971006e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRPC6 ACTN1 NFIA PLXNA1 FOXC1 PDZD2

5.53e-0619710061a6b2ca94a4634c24cd95481576c955b20000a5f
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 COL6A3 TRPC6 TJP1 RBFOX1 PDZD2

5.53e-06197100644cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORBS2 ABCA13 MUC16 TRIM29 LMO7 TJP1

5.69e-0619810066218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 TRPC6 SORBS1 ACTN1 SVIL ADAMTSL2

5.69e-061981006637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM29 LMO7 TJP1 NECTIN4 FUT3 FOXC1

5.69e-061981006fb3965049cb1961de0d2e74370868e46aa5050c8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM29 LMO7 TJP1 NECTIN4 FUT3 FOXC1

5.69e-06198100672d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 COL6A3 TRPC6 TJP1 RBFOX1 PDZD2

5.69e-06198100676d46950c11cb4708866db0da54ce00d5c0adab8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 TRPC6 ACTN1 TJP1 SVIL ADAMTSL2

5.69e-061981006c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM29 LMO7 TJP1 NECTIN4 FUT3 FOXC1

5.69e-061981006441608034c787e55691558a480dcd07e37419138
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM29 LMO7 TJP1 NECTIN4 FUT3 FOXC1

5.69e-0619810069f5726aedd1fb132feab717a029fa302306461b5
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FUT3

5.86e-061991006a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 TRPC6 ACTN1 HOXB5 TJP1 ADAMTSL2

5.86e-061991006aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FUT3

5.86e-061991006644197ff7e3299587881dd678836262e670ed4a8
ToppCell18-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

COL6A3 FOS ACTN1 MEOX2 HOXB5 NFIA

5.86e-061991006d65150d2e24c40aa82712e7f034f6772102bd293
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FOXC1

6.03e-062001006f386a86b127433cbac306950443355bd723080ff
ToppCellNS-moderate-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 MUC16 TRIM29 LMO7 TJP1 NECTIN4

6.03e-06200100685940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FOXC1

6.03e-0620010061c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 MUC16 TRIM29 LMO7 TJP1 FUT3

6.03e-0620010060cc7ff7b6a4eb05d2370ec2f3b9dbfe8cb0699de
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FOXC1

6.03e-062001006b75154417c215b8853186bff46d624ebd387ac4f
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 MUC16 TRIM29 LMO7 TJP1 FUT3

6.03e-062001006b9cede2e0939c6b60ce1aa16d7efaaae79354580
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 MUC16 TRIM29 LMO7 TJP1 FUT3

6.03e-062001006b762bf6f432eac05a476f6e2ab4da27dd13a2317
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 MUC16 TRIM29 LMO7 TJP1 FUT3

6.03e-0620010064c63204e0d868dd4c11c1604a238624a3ad54485
ToppCellSevere_COVID-19-Epithelial|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ABCA13 MUC16 TRIM29 LMO7 TJP1 FUT3

6.03e-06200100649910efb6d888c208cd50530b03af19f87070630
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC16 TRIM29 LMO7 TJP1 NECTIN4 FOXC1

6.03e-06200100603051d2190244208905e1611019d4b8fd200bae0
Diseasesevere combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive (implicated_via_orthology)

RAG2 PRKDC

1.05e-052962DOID:0090013 (implicated_via_orthology)
Diseasesevere combined immunodeficiency (implicated_via_orthology)

RAG2 PRKDC

3.14e-053962DOID:627 (implicated_via_orthology)
DiseaseTransitional cell carcinoma of bladder

FLT1 RET

6.26e-054962C0279680
Diseaseage at assessment, pelvic organ prolapse

SORBS2 TJP1 RBFOX1

3.75e-0443963EFO_0004710, EFO_0008007
Diseasepeptide measurement

FLT1 ABCA13 ZC3H18 RBFOX1

4.51e-04109964EFO_0010520
Diseaseimmature platelet fraction

SORBS1 ACTN1 SLFN14 TRPM3

5.34e-04114964EFO_0009187
Diseaseimmature platelet measurement

ACTN1 SLFN14 TRPM3 SVIL

6.28e-04119964EFO_0803541
Diseasesusceptibility to rubella infection measurement

TRPM3 RBFOX1 PDZD2

6.57e-0452963EFO_0008418
DiseaseMetastatic melanoma

GUCY2C GUCY2D PRKDC

7.34e-0454963C0278883
DiseaseAstigmatism

SGSM1 ABCA13 LMO7 RBFOX1

8.49e-04129964HP_0000483
Diseasesevere combined immunodeficiency (is_implicated_in)

RAG2 RFXANK

9.29e-0414962DOID:627 (is_implicated_in)
Diseasemyocardial infarction

ARHGAP42 COL6A3 FLT1 AHDC1 FOXC1 PDZD2

1.01e-03350966EFO_0000612
Diseaseresponse to opioid

MUC16 RBFOX1 ADAMTSL2

1.05e-0361963EFO_0008541
DiseaseSpondyloepiphyseal Dysplasia

FLT1 ADAMTSL2

1.22e-0316962C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLT1 ADAMTSL2

1.22e-0316962C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

FLT1 ADAMTSL2

1.22e-0316962C4551479
DiseaseSchwartz-Jampel Syndrome

FLT1 ADAMTSL2

1.22e-0316962C0036391
DiseaseMelnick-Needles Syndrome

FLT1 ADAMTSL2

1.22e-0316962C0025237
DiseaseVan Buchem disease

FLT1 ADAMTSL2

1.38e-0317962C0432272
Diseaseage at onset, Myopia

FLT1 TRPM3 NFIA RBFOX1

1.48e-03150964EFO_0004847, HP_0000545
Diseasediastolic blood pressure, systolic blood pressure

FLT1 CEP85 PSMB4 TMCC3 TRPM3 GUCY2D SVIL RBFOX1

1.56e-03670968EFO_0006335, EFO_0006336
DiseaseOsteochondrodysplasias

FLT1 ADAMTSL2

1.73e-0319962C0029422
DiseaseDyschondroplasias

FLT1 ADAMTSL2

1.73e-0319962C0013366
DiseaseMultiple Epiphyseal Dysplasia

FLT1 ADAMTSL2

1.92e-0320962C0026760
DiseaseSevere Combined Immunodeficiency

RAG2 PRKDC

1.92e-0320962C0085110
Diseasepars triangularis volume measurement

FOXB1 RBFOX1

1.92e-0320962EFO_0010321
DiseaseRenal glomerular disease

TRPC6 CREBBP

2.53e-0323962C0268731
DiseaseGlomerulopathy Assessment

TRPC6 CREBBP

2.53e-0323962C4521256
DiseaseQRS duration

ARHGAP42 SLC38A2 NFIA RBFOX1 HEATR5B

2.94e-03298965EFO_0005055
Diseaseblood rubidium measurement

ABCA13 MDGA1

3.24e-0326962EFO_0021529

Protein segments in the cluster

PeptideGeneStartEntry
MASSSTVPLGFHYET

BCL2L13

1

Q9BXK5
FSPSGYLSDTEESNM

CEP152

1611

O94986
DSVPGALDYMSFSTA

ACTN1

871

P12814
SDMPYRAAALSATSA

CCIN

311

Q13939
GDPAMISSDTSYLSS

ACCS

51

Q96QU6
EMSPSKNSFISYSRG

ADGRG4

1276

Q8IZF6
SYSRGTPSLEMTDTG

ADGRG4

1286

Q8IZF6
SSRPMYGAVTSFLHS

FBXO4

156

Q9UKT5
DSGEMSESFPYRTKA

CREBBP

1381

Q92793
MLSAGSFSSPYEHLS

CACHD1

656

Q5VU97
PDSSYGSSFFTMDLN

ABCA13

146

Q86UQ4
DLGLDYYSGDSSMSP

AHDC1

1311

Q5TGY3
LSDLESSSYYSMSPG

NFIA

246

Q12857
FGGRSYMPSTHRTTE

RAG2

156

P55895
ELSYPMISAGSFGLS

GUCY2C

136

P25092
STPDSFMDPASALYR

PSMB4

26

P28070
TSGPTMRYLRTSQDF

NUP205

1076

Q92621
EVSPTGSFSAHYLSM

LEMD3

461

Q9Y2U8
LTPYTTFGAGDMASR

MDGA1

721

Q8NFP4
STESSDYLRVASGPM

FAM90A23

136

A8MXZ1
LSSSLEPSYAEGSQM

MUC16

1731

Q8WXI7
SSFYPSAEGRAMSKT

PADI6

441

Q6TGC4
LDIAPRYSSFLMGAS

SLC17A3

341

O00476
ARSVPDMDLSGSFYA

FOS

286

P01100
ATYMLDPARGSFLSA

GUCY2D

416

Q02846
ARFSIPSMTEDYAGR

LILRB4

81

Q8NHJ6
STESSDYLRVASGPM

FAM90A1

136

Q86YD7
TLLYDSAPSGRFGTM

PHKA1

1186

P46020
QSSSYLDDSSPTGLM

ARNTL2

531

Q8WYA1
ANLTYMPSSSGSARS

DUSP10

56

Q9Y6W6
STESSDYLRVASGPM

FAM90A22

136

A8MWA6
SRYESMLRTASSPDS

PLXNA1

1621

Q9UIW2
PSLSSMYGDAEDSSS

PDZD2

1546

O15018
DYSDVDSFTGSPVSM

DEFB125

81

Q8N687
TRGISSLPRSYTMDD

LMO7

921

Q8WWI1
KMLSPGFDSSVYSDL

ADAMTSL2

651

Q86TH1
GRSDHMSYPELSTSS

MEOX2

31

P50222
MNSFLEYPILSSGDS

HOXA1

6

P49639
FMYLRPSSSYALDTD

OR5C1

261

Q8NGR4
EDGIMSGYRRPTSSA

PAQR6

21

Q6TCH4
FLMYSDDVLRSPSGS

ITGB4

1346

P16144
DSATPISMASGDYSA

FOXB1

226

Q99853
SSMPRYADASGRNTL

SBF1

1251

O95248
SGSSLSGSYRDPAAM

HOXB5

26

P09067
DEYTLMRATFSGSAG

IRS2

596

Q9Y4H2
SVYDRSSQGRPSSMY

UPF1

956

Q92900
GPGFASTDISMYTLS

CACNG8

296

Q8WXS5
TSPEAVSGYSFAMAA

HEATR5B

496

Q9P2D3
TTGLFLAMHYSPDAS

MT-CYB

46

P00156
RMSPTYSSDPESSDY

ELOA

186

Q14241
MAFPSSQSLYRTSGA

FOXC1

531

Q12948
RASTPYSIDSDSLGM

FOXJ3

176

Q9UPW0
YMGSTSPSRHFSSLD

POLQ

171

O75417
SPGLSRDLMYFSGAT

CEP85

141

Q6P2H3
FSDEPRTMFSLDTYS

COL6A3

286

P12111
FYHPSLLGSMDSTTA

BARHL2

316

Q9NY43
DSRRYTDGMLPFSSG

CEP192

316

Q8TEP8
YSFETMAPTGLSSLT

GPR63

46

Q9BZJ6
MASDADDPTYGSSAR

CDH22

191

Q9UJ99
PLDFSSLMSSEYESR

CCDC168

2126

Q8NDH2
TDFMGLFKSSRYDPS

CRYBG1

981

Q9Y4K1
RYDPSISFSGMSLSD

CRYBG1

991

Q9Y4K1
STESSDYLRVARGPM

FAM90A20P

136

A6NIJ5
STESSDYLRVASGPM

FAM90A24P

136

P0C7X0
LTTEADSGYTPMDLA

RFXANK

216

O14593
LSPSGKTTDYAFEMA

ADHFE1

36

Q8IWW8
TMSYRSDSDIFTPYG

FUT3

156

P21217
MSSAPASGSVRARYL

PUSL1

1

Q8N0Z8
EYSEMGSSFSVSPKA

RTN4

296

Q9NQC3
EGSSMYSAPSSLVYT

RBFOX1

236

Q9NWB1
SSSFSLKGYPSLMRS

TRIM29

536

Q14134
NMSPDTLALFSETAY

SLFN14

756

P0C7P3
MPGSDTALTVDRTYS

TMCC3

1

Q9ULS5
RDASSLYPGTETMGL

SVIL

161

O95425
MEGSSSYEVPSVAAA

LRRC27

1

Q9C0I9
IPDRFMGSSSGADRY

IGLV4-3

81

A0A075B6K6
DTSRPLGDSMYSSAL

NBR1

741

Q14596
MGLPTLEFSDSYLDS

ARHGAP42

1

A6NI28
EVMTRGTASSPSYRF

NCOA1

316

Q15788
GETLRSTFPSYMAEG

ODAD4

6

Q96NG3
STESSDYLRVASGPM

FAM90A12P

136

A8MX19
PYTDSRFRNSSMSLD

NAV2

1601

Q8IVL1
PLGVTTSDTSYSDMA

SETD5

6

Q9C0A6
SSGCSLYESSDLPLM

PRDM1

786

O75626
EKESPGLSFLMSYTS

SIX6OS1

466

Q8N1H7
GLSFLMSYTSRSPGL

SIX6OS1

471

Q8N1H7
MSYTSRSPGLNLFDS

SIX6OS1

476

Q8N1H7
RESPRSYSSTLTDMG

SORBS2

836

O94875
LSSSSATERYPMFTL

ATG4D

416

Q86TL0
GTDEMESSSYRDRSP

PHF6

186

Q8IWS0
SYGASMELLSARETF

TAS1R3

166

Q7RTX0
ISARSSEPFYSDDKM

USP21

186

Q9UK80
MGRFSISPDEDSSSY

SLC38A2

6

Q96QD8
LSMSYSFDLSDVTTP

SPIRE1

401

Q08AE8
SMDTRSFSSDYTHLP

TRPM3

1491

Q9HCF6
EMPCAFRASGATSYS

VSTM2B

46

A6NLU5
LSYFMYSDSDSEPTG

RLIM

416

Q9NVW2
DYMDLPFSSSPSRSA

SORBS1

936

Q9BX66
STDISDVSRSMFLYP

HEATR9

6

A2RTY3
MAERGYSFSLTTFSP

PSMA2

1

P25787
GSMDDRPSLSARDYV

SGSM1

231

Q2NKQ1
GPSYMSSLSYLADST

PRKDC

2021

P78527
SYSSSGARRPSLDSM

RET

686

P07949
PGSEYSMYSTDSRHT

TJP1

826

Q07157
NRGPAYMFSDRSTSL

TRPC6

81

Q9Y210
DYQGDSSTLLASPML

FLT1

1241

P17948
GSRSYCLDSSSPMEV

SOCS6

236

O14544
MYADLASPVSSASSR

ZC3H18

731

Q86VM9
SLFYSPSSPMSSDDE

WNK3

1511

Q9BYP7
TEGPYDSLDYMTTTR

MXRA5

1286

Q9NR99
SERISRFDTMYDGPS

PPP1R9A

121

Q9ULJ8
MSEEPEGRSYSTLTT

NECTIN4

436

Q96NY8