Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II C-terminal domain binding	BRD4 RPRD2 SCAF4	7.57e-06	11	73	3	GO:0099122
GeneOntologyMolecularFunction	CCR4-NOT complex binding	RC3H1 GARRE1	3.95e-05	3	73	2	GO:1905762
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	FOXO1 MYPOP ZBTB39 CEBPB YLPM1 HES1 SKI	1.67e-04	320	73	7	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	FOXO1 MYPOP ZBTB39 CEBPB YLPM1 HES1 SKI	1.88e-04	326	73	7	GO:0001217
GeneOntologyMolecularFunction	actin binding	MAP1A XIRP2 PHACTR4 WIPF3 SYN1 AFDN WASF1 ADD1	3.55e-04	479	73	8	GO:0003779
GeneOntologyMolecularFunction	RNA polymerase II complex binding	BRD4 RPRD2 SCAF4	3.90e-04	39	73	3	GO:0000993
GeneOntologyMolecularFunction	RNA polymerase core enzyme binding	BRD4 RPRD2 SCAF4	5.96e-04	45	73	3	GO:0043175
GeneOntologyMolecularFunction	protein domain specific binding	HOXA3 SHANK1 PTPN12 CEBPA WIPF3 WT1 AFDN HES1 SKI CBLB	1.26e-03	875	73	10	GO:0019904
GeneOntologyMolecularFunction	chromatin binding	FOXO1 TRIM66 CEBPA CEBPB ASXL3 BRD4 HES1 RERE SKI	1.45e-03	739	73	9	GO:0003682
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXA3 FOXO1 MYPOP ZBTB39 CEBPA CEBPB ZNF652 YLPM1 WT1 ZBTB47 HES1 ONECUT3 SKI	1.67e-03	1412	73	13	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase binding	BRD4 RPRD2 SCAF4	1.74e-03	65	73	3	GO:0070063
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	BRD4 RPRD2 SCAF4	1.82e-03	66	73	3	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	BRD4 RPRD2 SCAF4	1.82e-03	66	73	3	GO:0001098
GeneOntologyMolecularFunction	SH3 domain binding	SHANK1 PTPN12 WIPF3 CBLB	1.87e-03	143	73	4	GO:0017124
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	2.39e-03	372	73	6	GO:0061630
GeneOntologyMolecularFunction	HMG box domain binding	HOXA3 CEBPA	3.17e-03	23	73	2	GO:0071837
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	3.34e-03	398	73	6	GO:0061659
GeneOntologyMolecularFunction	cytoskeletal anchor activity	MAP1A SYN1	3.45e-03	24	73	2	GO:0008093
GeneOntologyBiologicalProcess	positive regulation of adherens junction organization	PTPN23 ADD1	1.24e-05	2	73	2	GO:1903393
GeneOntologyCellularComponent	nuclear body	SETD1B CPSF6 YLPM1 MAMLD1 WT1 ACIN1 PTPN23 AFDN SMN1 RERE SRCAP SKI ADD1	1.11e-05	903	72	13	GO:0016604
GeneOntologyCellularComponent	C/EBP complex	CEBPA CEBPB	1.17e-05	2	72	2	GO:1990647
GeneOntologyCellularComponent	CHOP-C/EBP complex	CEBPA CEBPB	3.50e-05	3	72	2	GO:0036488
GeneOntologyCellularComponent	postsynaptic density	SHANK1 PRR12 IQSEC3 GRID2IP MAP1A SYN1 AFDN ADD1	1.58e-04	451	72	8	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	SHANK1 PRR12 IQSEC3 GRID2IP MAP1A SYN1 AFDN ADD1	2.31e-04	477	72	8	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	SHANK1 PRR12 IQSEC3 GRID2IP MAP1A SYN1 AFDN ADD1	3.30e-04	503	72	8	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	SHANK1 PRR12 IQSEC3 GRID2IP MAP1A SYN1 AFDN ADD1	4.27e-04	523	72	8	GO:0098984
MousePheno	abnormal rostral-caudal body axis extension	PTPN12 PHACTR4 AFDN	4.20e-05	17	57	3	MP:0003885
MousePheno	decreased skeletal muscle fiber size	CEBPB SMN1 SKI WASF1 EPG5	4.56e-05	97	57	5	MP:0009400
Domain	Znf_RING/FYVE/PHD	TRIM66 TRIM67 PHF3 RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	6.53e-05	459	72	9	IPR013083
Domain	C/EBP_chordates	CEBPA CEBPB	8.75e-05	4	72	2	IPR016468
Domain	ZF_RING_1	TRIM67 RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	1.29e-04	291	72	7	PS00518
Domain	C/EBP	CEBPA CEBPB	1.45e-04	5	72	2	IPR031106
Domain	ZF_RING_2	TRIM67 RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	1.49e-04	298	72	7	PS50089
Domain	zf-C3HC4	TRIM67 RC3H1 RNF44 RNF38 SYVN1 CBLB	2.19e-04	223	72	6	PF00097
Domain	Znf_RING	TRIM67 RC3H1 RNF44 RNF38 IRF2BPL SYVN1 CBLB	2.58e-04	326	72	7	IPR001841
Domain	RNA_pol_II-bd	RPRD2 SCAF4	3.04e-04	7	72	2	IPR006903
Domain	CTD_bind	RPRD2 SCAF4	3.04e-04	7	72	2	PF04818
Domain	-	TRIM66 TRIM67 PHF3 RC3H1 RNF44 RNF38 SYVN1 CBLB	3.26e-04	449	72	8	3.30.40.10
Domain	RPR	RPRD2 SCAF4	4.04e-04	8	72	2	SM00582
Domain	CID	RPRD2 SCAF4	4.04e-04	8	72	2	PS51391
Domain	CID_dom	RPRD2 SCAF4	4.04e-04	8	72	2	IPR006569
Domain	Znf_C3HC4_RING-type	TRIM67 RNF44 RNF38 SYVN1 CBLB	5.31e-04	172	72	5	IPR018957
Domain	zf-RING_2	RNF44 RNF38 SYVN1	1.06e-03	52	72	3	PF13639
Domain	RING	TRIM67 RC3H1 RNF44 RNF38 SYVN1 CBLB	1.14e-03	305	72	6	SM00184
Domain	WH2	WIPF3 WASF1	1.29e-03	14	72	2	SM00246
Domain	Bbox_C	TRIM66 TRIM67	1.49e-03	15	72	2	IPR003649
Domain	BBC	TRIM66 TRIM67	1.49e-03	15	72	2	SM00502
Domain	RRM	SETD1B CPSF6 ACIN1 TNRC6C SCAF4	1.50e-03	217	72	5	SM00360
Domain	WH2	WIPF3 WASF1	1.70e-03	16	72	2	PF02205
Domain	RRM_dom	SETD1B CPSF6 ACIN1 TNRC6C SCAF4	1.83e-03	227	72	5	IPR000504
Domain	bZIP_2	CEBPA CEBPB	1.92e-03	17	72	2	PF07716
Domain	-	SETD1B CPSF6 ACIN1 TNRC6C SCAF4	2.51e-03	244	72	5	3.30.70.330
Domain	WH2_dom	WIPF3 WASF1	2.94e-03	21	72	2	IPR003124
Domain	Nucleotide-bd_a/b_plait	SETD1B CPSF6 ACIN1 TNRC6C SCAF4	3.19e-03	258	72	5	IPR012677
Domain	WH2	WIPF3 WASF1	3.83e-03	24	72	2	PS51082
Domain	SH3_2	SHANK1 MYO15B FYB1	4.47e-03	86	72	3	IPR011511
Domain	SH3_2	SHANK1 MYO15B FYB1	4.47e-03	86	72	3	PF07653
Domain	-	RPRD2 SCAF4	4.49e-03	26	72	2	1.25.40.90
Domain	AT_hook	PRR12 SRCAP	4.83e-03	27	72	2	SM00384
Domain	AT_hook_DNA-bd_motif	PRR12 SRCAP	4.83e-03	27	72	2	IPR017956
Domain	ENTH_VHS	RPRD2 SCAF4	5.56e-03	29	72	2	IPR008942
Domain	ZF_PHD_2	TRIM66 PHF3 ASXL3	5.90e-03	95	72	3	PS50016
Domain	UBA	TNRC6C CBLB	5.95e-03	30	72	2	SM00165
Domain	ZF_PHD_1	TRIM66 PHF3 ASXL3	6.07e-03	96	72	3	PS01359
Domain	UBA	TNRC6C CBLB	8.48e-03	36	72	2	PF00627
Domain	PTPc	PTPN12 PTPN23	8.48e-03	36	72	2	SM00194
Domain	RRM_1	SETD1B CPSF6 TNRC6C SCAF4	8.52e-03	208	72	4	PF00076
Domain	BROMODOMAIN_1	TRIM66 BRD4	8.95e-03	37	72	2	PS00633
Domain	MYB_LIKE	MYPOP RERE	9.42e-03	38	72	2	PS50090
Domain	Bromodomain	TRIM66 BRD4	9.42e-03	38	72	2	PF00439
Domain	TYR_PHOSPHATASE_PTP	PTPN12 PTPN23	9.90e-03	39	72	2	PS50055
Domain	-	ZC3H10 RC3H1	1.04e-02	40	72	2	4.10.1000.10
Domain	PTPase_domain	PTPN12 PTPN23	1.09e-02	41	72	2	IPR000242
Domain	Y_phosphatase	PTPN12 PTPN23	1.09e-02	41	72	2	PF00102
Domain	BROMODOMAIN_2	TRIM66 BRD4	1.09e-02	41	72	2	PS50014
Domain	BROMO	TRIM66 BRD4	1.14e-02	42	72	2	SM00297
Domain	Bromodomain	TRIM66 BRD4	1.14e-02	42	72	2	IPR001487
Pathway	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS	FOXO1 PTPN12 CEBPB CPSF6 MAMLD1 FIP1L1 HES1 TNRC6C SYVN1 GAB1	1.91e-06	464	46	10	M27547
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	FOXO1 MAMLD1 HES1 ONECUT3	1.01e-05	42	46	4	M17541
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	MAMLD1 HES1 ONECUT3	1.77e-05	16	46	3	M27121
Pathway	WP_EGFR1_SIGNALING_PATHWAY	FOXO1 PTPN12 CEBPA CEBPB CBLB GAB1	3.12e-05	188	46	6	MM15828
Pathway	WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS	FOXO1 CEBPA CEBPB	4.79e-05	22	46	3	M39414
Pathway	WP_WHITE_FAT_CELL_DIFFERENTIATION	FOXO1 CEBPA CEBPB	1.51e-04	32	46	3	M39333
Pathway	PID_CMYB_PATHWAY	CEBPA CEBPB HES1 SKI	1.58e-04	84	46	4	M195
Pathway	WP_WHITE_FAT_CELL_DIFFERENTIATION	FOXO1 CEBPA CEBPB	1.66e-04	33	46	3	MM15869
Pathway	WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING	CEBPA CEBPB HES1	2.34e-04	37	46	3	M39817
Pathway	WP_IL6_SIGNALING_PATHWAY	FOXO1 CEBPB MAPKAPK2 GAB1	3.10e-04	100	46	4	MM15826
Pathway	PID_IL6_7_PATHWAY	FOXO1 CEBPB GAB1	4.77e-04	47	46	3	M183
Pathway	REACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAMLD1 HES1	6.73e-04	12	46	2	M27159
Pathway	WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS	CEBPA CEBPB	7.94e-04	13	46	2	M39753
Pathway	WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES	CEBPA CEBPB HES1	8.41e-04	57	46	3	M39877
Pathway	WP_HYPOXIADEPENDENT_SELFRENEWAL_OF_MYOBLASTS	FOXO1 HES1	9.25e-04	14	46	2	MM15832
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAMLD1 HES1	9.25e-04	14	46	2	M27808
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	CPSF6 PHF3 BRD4 PHACTR4 YLPM1 WIPF3 ACIN1 RPRD2 ZNF318 SRCAP ADD1 SCAF4	6.50e-10	506	73	12	30890647
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 CPSF6 BICRA RC3H1 FBRSL1 TNRC6C VPS37B GARRE1	1.17e-09	152	73	8	38360978
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PHF3 BRD4 PHACTR4 YLPM1 ACIN1 PTPN23 AFDN RPRD2 ZNF318 SRCAP ADD1 SCAF4	1.63e-09	549	73	12	38280479
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PHF3 BRD4 NAF1 PHACTR4 YLPM1 FIP1L1 ACIN1 AFDN IRF2BPL ZNF318 RERE ADD1 SCAF4	7.51e-09	774	73	13	15302935
Pubmed	Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells.	FOXO1 CEBPA CEBPB	8.87e-09	3	73	3	11893744
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAP1A XIRP2 BICRA YLPM1 WT1 RNF38 IRF2BPL VPS37B WNK2 GAB1	2.33e-08	430	73	10	35044719
Pubmed	Human transcription factor protein interaction networks.	PRR12 BICRA RC3H1 YLPM1 FBRSL1 FIP1L1 SMN1 IRF2BPL RPRD2 ZNF318 RERE TNRC6C SRCAP SKI GARRE1 SCAF4	3.50e-08	1429	73	16	35140242
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 MYPOP ZBTB39 CEBPA CEBPB PHF3 BRD4 YLPM1 FIP1L1 ACIN1 RPRD2 ZNF318 SRCAP SKI SCAF4	6.41e-08	1294	73	15	30804502
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 CPSF6 PHF3 BRD4 YLPM1 RPRD2 RERE SKI	9.76e-08	268	73	8	33640491
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IQSEC3 SETD1B PHF3 PPM1E ACIN1 RERE TNRC6C SYVN1 EPG5	1.89e-07	407	73	9	12693553
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	CPSF6 RC3H1 YLPM1 FIP1L1 ACIN1 RPRD2 SCAF4	4.21e-07	220	73	7	24550385
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 ZC3H10 ZBTB39 CEBPA CEBPB CPSF6 BICRA ZNF652 BRD4 WT1 FIP1L1 ZNF318 SCAF4	4.53e-07	1103	73	13	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MST1R PRR12 PDE4A SETD1B CEBPB MAPKAPK2 BICRA BRD4 FBRSL1 TNRC6C SYVN1 SRCAP WNK2	4.62e-07	1105	73	13	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRIM66 MAP1A FAM120C BICRA BRD4 NAF1 FBRSL1 FIP1L1 ZNF318 RERE SRCAP SKI GARRE1	5.16e-07	1116	73	13	31753913
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PTPN12 MAP1A CPSF6 NAF1 YLPM1 ACIN1 PTPN23 RPRD2 ZNF318 SRCAP ADD1 SCAF4	5.36e-07	934	73	12	33916271
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 IQSEC3 PDE4A TRIM67 FAM120C YLPM1 SYN1 AFDN ZNF318 WASF1 WNK2 ADD1	7.39e-07	963	73	12	28671696
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	CPSF6 BRD4 YLPM1 FIP1L1 RPRD2 SCAF4	9.11e-07	154	73	6	16055720
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 CEBPB CPSF6 YLPM1 FIP1L1 RPRD2	2.26e-06	180	73	6	35198878
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	CPSF6 PHF3 BRD4 YLPM1 ACIN1 RPRD2 ZNF318	2.26e-06	283	73	7	30585729
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	PTPN12 WIPF3 AFDN CBLB GAB1	2.64e-06	103	73	5	21706016
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1B PHF3 YLPM1 FIP1L1 SMN1 RPRD2 ZNF318 SRCAP	4.03e-06	440	73	8	34244565
Pubmed	Identification and characterization of CCAAT enhancer-binding protein (C/EBP) as a transcriptional activator for Epstein-Barr virus oncogene latent membrane protein 1.	CEBPA CEBPB	4.35e-06	2	73	2	22013073
Pubmed	CCAAT/enhancer binding proteins alpha and beta are transcriptional activators of the brown fat uncoupling protein gene promoter.	CEBPA CEBPB	4.35e-06	2	73	2	8297376
Pubmed	Translation start site multiplicity of the CCAAT/enhancer binding protein alpha mRNA is dictated by a small 5' open reading frame.	CEBPA CEBPB	4.35e-06	2	73	2	7838705
Pubmed	Upregulation of HOXA3 by isoform-specific Wilms tumour 1 drives chemotherapy resistance in acute myeloid leukaemia.	HOXA3 WT1	4.35e-06	2	73	2	38867543
Pubmed	Effects of age on the posttranscriptional regulation of CCAAT/enhancer binding protein alpha and CCAAT/enhancer binding protein beta isoform synthesis in control and LPS-treated livers.	CEBPA CEBPB	4.35e-06	2	73	2	9614188
Pubmed	An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis.	CEBPA CEBPB	4.35e-06	2	73	2	12441050
Pubmed	C/EBPalpha expression is partially regulated by C/EBPbeta in response to DNA damage and C/EBPalpha-deficient fibroblasts display an impaired G1 checkpoint.	CEBPA CEBPB	4.35e-06	2	73	2	19581927
Pubmed	Reciprocal expression of CCAAT/enhancer binding proteins alpha and beta in hepatoblastomas and its prognostic significance.	CEBPA CEBPB	4.35e-06	2	73	2	17203171
Pubmed	The CCAAT/enhancer binding protein (C/EBP alpha) gene (CEBPA) maps to human chromosome 19q13.1 and the related nuclear factor NF-IL6 (C/EBP beta) gene (CEBPB) maps to human chromosome 20q13.1.	CEBPA CEBPB	4.35e-06	2	73	2	1427819
Pubmed	Concomitant WT1 mutations predict poor prognosis in acute myeloid leukemia patients with double mutant CEBPA.	CEBPA WT1	4.35e-06	2	73	2	29773598
Pubmed	Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments.	CEBPA CEBPB	4.35e-06	2	73	2	24273171
Pubmed	CCAAT/enhancer binding protein-mediated role of thyroid hormone in the developmental expression of the kidney androgen-regulated protein gene in proximal convoluted tubules.	CEBPA CEBPB	4.35e-06	2	73	2	16150866
Pubmed	C/EBPbeta is required for 'emergency' granulopoiesis.	CEBPA CEBPB	4.35e-06	2	73	2	16751774
Pubmed	Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes.	CEBPA CEBPB	4.35e-06	2	73	2	14688407
Pubmed	The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.	CEBPA CEBPB	4.35e-06	2	73	2	29849099
Pubmed	Inhibition of CCAAT/enhancer-binding protein alpha and beta translation by upstream open reading frames.	CEBPA CEBPB	4.35e-06	2	73	2	9545285
Pubmed	Role of the isoforms of CCAAT/enhancer-binding protein in the initiation of phosphoenolpyruvate carboxykinase (GTP) gene transcription at birth.	CEBPA CEBPB	4.35e-06	2	73	2	9334201
Pubmed	Evidence for posttranscriptional regulation of C/EBPalpha and C/EBPbeta isoform expression during the lipopolysaccharide-mediated acute-phase response.	CEBPA CEBPB	4.35e-06	2	73	2	8628296
Pubmed	C/EBPβ (CEBPB) protein binding to the C/EBP\|CRE DNA 8-mer TTGC\|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotide.	CEBPA CEBPB	4.35e-06	2	73	2	25779641
Pubmed	Expression of C/EBPbeta from the C/ebpalpha gene locus is sufficient for normal hematopoiesis in vivo.	CEBPA CEBPB	4.35e-06	2	73	2	11877276
Pubmed	C/EBPbeta, but not C/EBPalpha, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland.	CEBPA CEBPB	4.35e-06	2	73	2	9637692
Pubmed	The Papillomavirus E2 protein binds to and synergizes with C/EBP factors involved in keratinocyte differentiation.	CEBPA CEBPB	4.35e-06	2	73	2	12692227
Pubmed	Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.	CEBPA CEBPB	4.35e-06	2	73	2	21326902
Pubmed	Triptolide inhibits IL-12/IL-23 expression in APCs via CCAAT/enhancer-binding protein alpha.	CEBPA CEBPB	4.35e-06	2	73	2	20194724
Pubmed	Foxo1 increases pro-inflammatory gene expression by inducing C/EBPbeta in TNF-alpha-treated adipocytes.	FOXO1 CEBPB	4.35e-06	2	73	2	19026986
Pubmed	Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation.	PDE4A MAPKAPK2	4.35e-06	2	73	2	21323643
Pubmed	C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage.	CEBPA CEBPB	4.35e-06	2	73	2	10022857
Pubmed	Translational control of C/EBPalpha and C/EBPbeta isoform expression.	CEBPA CEBPB	4.35e-06	2	73	2	10921906
Pubmed	CCAAT/enhancer binding protein alpha (C/EBPalpha) is an important mediator of mouse C/EBPbeta protein isoform production.	CEBPA CEBPB	4.35e-06	2	73	2	9918941
Pubmed	SYVN1 ubiquitinates FoxO1 to induce β-catenin nuclear translocation, PD-L1-mediated metastasis, and immune evasion of hepatocellular carcinoma.	FOXO1 SYVN1	4.35e-06	2	73	2	37099251
Pubmed	C/EBPalpha and C/EBPbeta are required for Sebocyte differentiation and stratified squamous differentiation in adult mouse skin.	CEBPA CEBPB	4.35e-06	2	73	2	20352127
Pubmed	Upstream open reading frames: molecular switches in (patho)physiology.	CEBPA CEBPB	4.35e-06	2	73	2	20726009
Pubmed	Induction of a cell stress response gene RTP801 by DNA damaging agent methyl methanesulfonate through CCAAT/enhancer binding protein.	CEBPA CEBPB	4.35e-06	2	73	2	15751966
Pubmed	Novel Function of a Transcription Factor WT1 in Regulating Decidualization in Human Endometrial Stromal Cells and Its Molecular Mechanism.	CEBPB WT1	4.35e-06	2	73	2	28977591
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CPSF6 PHF3 BICRA BRD4 YLPM1 FIP1L1 ACIN1 AFDN RPRD2 ZNF318 SCAF4	4.71e-06	954	73	11	36373674
Pubmed	Protein phosphatase 1γ isoforms linked interactions in the brain.	PHACTR4 YLPM1 RPRD2 ZNF318	6.48e-06	57	73	4	23080069
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	FAM120C CPSF6 YLPM1 FIP1L1 ACIN1 SMN1 SRCAP	7.66e-06	341	73	7	32971831
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRR12 TRIM66 MYO15B ZBTB39 RC3H1 PTPN23 IRF2BPL SCAF4	9.24e-06	493	73	8	15368895
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	FOXO1 CPSF6 MAPKAPK2 NAF1 FBRSL1 FIP1L1 SMN1 RPRD2 TNRC6C VPS37B ADD1	1.04e-05	1038	73	11	26673895
Pubmed	Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha.	CEBPA CEBPB ADD1	1.15e-05	21	73	3	11940593
Pubmed	Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group.	CEBPA WT1	1.30e-05	3	73	2	19221039
Pubmed	A positive regulatory domain in CCAAT/enhancer binding protein β (C/EBPΒ) is required for the glucocorticoid-mediated displacement of histone deacetylase 1 (HDAC1) from the C/ebpα promoter and maximum adipogenesis.	CEBPA CEBPB	1.30e-05	3	73	2	23456364
Pubmed	PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.	FOXO1 BRD4	1.30e-05	3	73	2	28446439
Pubmed	Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.	CEBPA CEBPB	1.30e-05	3	73	2	16166081
Pubmed	CCAAT/enhancer-binding proteins are key regulators of human type two deiodinase expression in a placenta cell line.	CEBPA CEBPB	1.30e-05	3	73	2	22689263
Pubmed	PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.	CEBPA CEBPB	1.30e-05	3	73	2	18981473
Pubmed	CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage.	CEBPA CEBPB	1.30e-05	3	73	2	24551078
Pubmed	Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK.	CEBPA CEBPB	1.30e-05	3	73	2	12821655
Pubmed	Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice.	CEBPA CEBPB	1.30e-05	3	73	2	26740594
Pubmed	Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins.	CEBPA CEBPB	1.30e-05	3	73	2	25749148
Pubmed	C/EBP alpha and beta mimic retinoic acid activation of IGFBP-5 in neuroblastoma cells by a mechanism independent from binding to their site.	CEBPA CEBPB	1.30e-05	3	73	2	15777798
Pubmed	Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition.	CPSF6 FIP1L1	1.30e-05	3	73	2	15937220
Pubmed	CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter.	CEBPA CEBPB	1.30e-05	3	73	2	19523687
Pubmed	Baccharis trimera (Less.) DC Exhibits an Anti-Adipogenic Effect by Inhibiting the Expression of Proteins Involved in Adipocyte Differentiation.	CEBPA CEBPB	1.30e-05	3	73	2	28604636
Pubmed	CCAAT/enhancer binding protein alpha, beta and delta gene variants: associations with obesity related phenotypes in the Leeds Family Study.	CEBPA CEBPB	1.30e-05	3	73	2	20460359
Pubmed	cAMP-induced Interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation.	CEBPA CEBPB	1.30e-05	3	73	2	12493739
Pubmed	Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA.	CEBPA CEBPB	1.30e-05	3	73	2	12873812
Pubmed	Lactation status influences expression of CCAAT/enhancer binding protein isoform mRNA in the mouse mammary gland.	CEBPA CEBPB	1.30e-05	3	73	2	9428809
Pubmed	Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element.	CEBPA CEBPB	1.30e-05	3	73	2	8657121
Pubmed	Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins.	CEBPA CEBPB	1.30e-05	3	73	2	12242300
Pubmed	Expression of the CCAAT/enhancer-binding proteins C/EBPalpha, C/EBPbeta and C/EBPdelta in breast cancer: correlations with clinicopathologic parameters and cell-cycle regulatory proteins.	CEBPA CEBPB	1.30e-05	3	73	2	12825852
Pubmed	Conserved amino acids within CCAAT enhancer-binding proteins (C/EBP(alpha) and beta) regulate phosphoenolpyruvate carboxykinase (PEPCK) gene expression.	CEBPA CEBPB	1.30e-05	3	73	2	11997389
Pubmed	Structural and functional characterization of the mouse p8 gene: promotion of transcription by the CAAT-enhancer binding protein alpha (C/EBPalpha) and C/EBPbeta trans-acting factors involves a C/EBP cis-acting element and other regions of the promoter.	CEBPA CEBPB	1.30e-05	3	73	2	10510303
Pubmed	Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs.	CEBPA CEBPB	1.30e-05	3	73	2	26762974
Pubmed	ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation.	CEBPA CEBPB	1.30e-05	3	73	2	9139739
Pubmed	Cell density and serum exposure modify the function of the glucocorticoid receptor C/EBP complex.	CEBPA CEBPB	1.30e-05	3	73	2	17989362
Pubmed	CCAAT/enhancer binding protein-mediated regulation of TGFβ receptor 2 expression determines the hepatoblast fate decision.	CEBPA CEBPB	1.30e-05	3	73	2	24284203
Pubmed	Regulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells.	CEBPA CEBPB	1.30e-05	3	73	2	12970736
Pubmed	SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex.	FOXO1 CEBPA	1.30e-05	3	73	2	17090532
Pubmed	The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium.	CEBPB WT1	1.30e-05	3	73	2	34478711
Pubmed	Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.	CEBPA CEBPB	1.30e-05	3	73	2	1840554
Pubmed	FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.	FOXO1 GAB1	1.30e-05	3	73	2	33786575
Pubmed	Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation.	CEBPA CEBPB	1.30e-05	3	73	2	29030964
Pubmed	Sequential regulation of diacylglycerol acyltransferase 2 expression by CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis.	CEBPA CEBPB	1.30e-05	3	73	2	17504763
Pubmed	Incidences and Prognostic Impact of c-KIT, WT1, CEBPA, and CBL Mutations, and Mutations Associated With Epigenetic Modification in Core Binding Factor Acute Myeloid Leukemia: A Multicenter Study in a Korean Population.	CEBPA WT1	1.30e-05	3	73	2	25932436
Pubmed	Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response.	CEBPA CEBPB	1.30e-05	3	73	2	1371993
Pubmed	T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.	CEBPA HES1	1.30e-05	3	73	2	24185616
Pubmed	Induction of granulocytic differentiation by 2 pathways.	CEBPA CEBPB	1.30e-05	3	73	2	12036869
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	PTPN12 PHF3 SYN1 SMN1 IRF2BPL ADD1	1.35e-05	246	73	6	15345747
Interaction	NCK2 interactions	MYPOP PTPN12 CPSF6 YLPM1 WIPF3 AFDN ONECUT3 CBLB FYB1 WASF1 VPS37B GAB1	1.39e-10	262	72	12	int:NCK2
Interaction	GRB2 interactions	MST1R PTPN12 CEBPA CEBPB TRIM67 MAP1A CPSF6 PHACTR4 YLPM1 WIPF3 SYN1 FIP1L1 PTPN23 AFDN CBLB WASF1 VPS37B GAB1	3.08e-10	806	72	18	int:GRB2
Interaction	ACTG1 interactions	PTPN12 CEBPA CEBPB TRIM67 MAP1A CPSF6 ASXL3 RC3H1 BRD4 PHACTR4 WIPF3 PRR11 SRCAP WASF1 ADD1	3.66e-10	520	72	15	int:ACTG1
Interaction	SNRPA interactions	ZC3H10 CEBPA TRIM67 PHF3 RC3H1 BRD4 YLPM1 FIP1L1 ACIN1 SMN1 RPRD2 ZNF318 SCAF4	1.40e-08	482	72	13	int:SNRPA
Interaction	ACTC1 interactions	TRIM67 CPSF6 PHF3 BICRA BRD4 PHACTR4 YLPM1 WIPF3 ACIN1 RPRD2 ZNF318 SRCAP WNK2 ADD1 SCAF4	1.82e-08	694	72	15	int:ACTC1
Interaction	TOP1 interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 PHF3 ASXL3 RC3H1 BRD4 YLPM1 FIP1L1 ACIN1 RPRD2 SRCAP SCAF4	1.90e-08	696	72	15	int:TOP1
Interaction	CPSF6 interactions	CEBPA TRIM67 CPSF6 PHF3 RC3H1 BRD4 YLPM1 FIP1L1 ACIN1 SMN1 RPRD2 ZNF318 SCAF4	3.91e-08	526	72	13	int:CPSF6
Interaction	SNRPC interactions	CEBPB CPSF6 PHF3 BRD4 YLPM1 FIP1L1 ACIN1 SMN1 RPRD2 ZNF318 RERE SCAF4	4.75e-08	440	72	12	int:SNRPC
Interaction	PRPF40A interactions	MST1R ZC3H10 CEBPB TRIM67 CPSF6 MAPKAPK2 BRD4 YLPM1 FIP1L1 ACIN1 WASF1 SCAF4	5.51e-08	446	72	12	int:PRPF40A
Interaction	CELF1 interactions	CEBPA CEBPB TRIM67 FAM120C CPSF6 RC3H1 BRD4 YLPM1 TNRC6C SCAF4	7.46e-08	288	72	10	int:CELF1
Interaction	FUBP3 interactions	CEBPA CEBPB TRIM67 FAM120C CPSF6 RC3H1 BRD4 YLPM1 TNRC6C GARRE1	9.95e-08	297	72	10	int:FUBP3
Interaction	HNRNPA1 interactions	FOXO1 CEBPA CEBPB TRIM67 FAM120C CPSF6 PHF3 ASXL3 RC3H1 BRD4 YLPM1 FIP1L1 ACIN1 AFDN SMN1 SCAF4	1.67e-07	945	72	16	int:HNRNPA1
Interaction	SMG7 interactions	PRR12 TRIM66 FAM120C CPSF6 RC3H1 YLPM1 RPRD2 ZNF318 TNRC6C GARRE1	1.93e-07	319	72	10	int:SMG7
Interaction	EYA4 interactions	PRR12 TRIM67 CPSF6 BICRA RC3H1 FBRSL1 TNRC6C VPS37B GARRE1	2.04e-07	243	72	9	int:EYA4
Interaction	YAP1 interactions	FOXO1 PRRG1 TRIM67 CPSF6 PHF3 BRD4 YLPM1 WT1 RNF38 ACIN1 AFDN RPRD2 ZNF318 SRCAP GAB1 ADD1 SCAF4	2.20e-07	1095	72	17	int:YAP1
Interaction	ALG13 interactions	PRR12 ZC3H10 TRIM66 FAM120C CPSF6 RC3H1 RERE GARRE1	2.89e-07	183	72	8	int:ALG13
Interaction	SCAF4 interactions	CEBPA CEBPB TRIM67 CPSF6 ACIN1 RPRD2 SCAF4	7.12e-07	141	72	7	int:SCAF4
Interaction	RECQL interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 PHF3 BRD4 ACIN1 RPRD2	8.74e-07	289	72	9	int:RECQL
Interaction	PRMT2 interactions	SHANK1 SETD1B PPM1E YLPM1 FIP1L1 CBLB	8.82e-07	91	72	6	int:PRMT2
Interaction	RSL1D1 interactions	MST1R ZC3H10 CEBPA CEBPB TRIM67 PHF3 RC3H1 BRD4 YLPM1 ZBTB47 PRR11	9.97e-07	479	72	11	int:RSL1D1
Interaction	P4HA1 interactions	TRIM66 CEBPB TRIM67 CPSF6 BRD4 YLPM1 FIP1L1 SMN1 SYVN1	1.13e-06	298	72	9	int:P4HA1
Interaction	UBAP2L interactions	FOXO1 CEBPB TRIM67 FAM120C CPSF6 RC3H1 FBRSL1 TNRC6C GARRE1	1.13e-06	298	72	9	int:UBAP2L
Interaction	PRRC2A interactions	CEBPA CEBPB TRIM67 FAM120C MAPKAPK2 RC3H1 BRD4 RERE TNRC6C GARRE1	1.18e-06	389	72	10	int:PRRC2A
Interaction	IRF2BPL interactions	CEBPB TRIM67 RC3H1 BRD4 IRF2BPL	1.27e-06	53	72	5	int:IRF2BPL
Interaction	SP7 interactions	PRR12 BICRA YLPM1 FBRSL1 RPRD2 ZNF318 RERE CBLB SCAF4	1.33e-06	304	72	9	int:SP7
Interaction	WBP11 interactions	JPH4 CEBPA CEBPB TRIM67 CPSF6 MAPKAPK2 BRD4	1.67e-06	160	72	7	int:WBP11
Interaction	AR interactions	FOXO1 PRR12 CEBPA CEBPB CPSF6 PHF3 BRD4 YLPM1 ACIN1 IRF2BPL RPRD2 ZNF318 RERE SRCAP SKI	1.80e-06	992	72	15	int:AR
Interaction	BAG2 interactions	FOXO1 TRIM66 CEBPB TRIM67 MAPKAPK2 RC3H1 BRD4 PHACTR4 PTPN23 IRF2BPL RPRD2 ZNF318	1.90e-06	622	72	12	int:BAG2
Interaction	CSTF2T interactions	CEBPA CEBPB TRIM67 CPSF6 BRD4 FIP1L1	2.05e-06	105	72	6	int:CSTF2T
Interaction	SARNP interactions	CEBPA CEBPB TRIM67 CPSF6 BRD4 ACIN1 SRCAP	2.31e-06	168	72	7	int:SARNP
Interaction	PRP4K interactions	ZC3H10 CEBPB TRIM67 CPSF6 MAPKAPK2 RC3H1 BRD4 FIP1L1 ACIN1	2.55e-06	329	72	9	int:PRP4K
Interaction	ARL6IP4 interactions	CEBPA CEBPB TRIM67 CPSF6 RNF38 GAB1	2.55e-06	109	72	6	int:ARL6IP4
Interaction	PABPC4 interactions	CEBPA CEBPB TRIM67 XIRP2 FAM120C RC3H1 YLPM1 TNRC6C PRR11 SKI	3.70e-06	442	72	10	int:PABPC4
Interaction	RRS1 interactions	ZC3H10 CEBPB TRIM67 RC3H1 BRD4 ZBTB47 ACIN1 PRR11 SCAF4	3.75e-06	345	72	9	int:RRS1
Interaction	RBM14 interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 RC3H1 BRD4 NAF1 YLPM1 FIP1L1 ACIN1	4.00e-06	553	72	11	int:RBM14
Interaction	BCAR1 interactions	PTPN12 SETD1B TRIM67 MAPKAPK2 BRD4 PTPN23 TNRC6C CBLB FYB1 GARRE1 WNK2	4.21e-06	556	72	11	int:BCAR1
Interaction	ARHGAP12 interactions	PRR12 TRIM67 PHACTR4 YLPM1 WASF1	4.42e-06	68	72	5	int:ARHGAP12
Interaction	PRRC2B interactions	TRIM66 JPH4 CEBPA TRIM67 FAM120C RC3H1 RERE GARRE1	4.65e-06	265	72	8	int:PRRC2B
Interaction	SMAP2 interactions	TRIM67 RC3H1 FBRSL1 PTPN23 TNRC6C SYVN1 GARRE1	5.03e-06	189	72	7	int:SMAP2
Interaction	BOP1 interactions	MST1R ZC3H10 TRIM67 RC3H1 BRD4 ACIN1 PRR11	5.39e-06	191	72	7	int:BOP1
Interaction	FAM120C interactions	TRIM66 TRIM67 FAM120C RC3H1 SMN1 TNRC6C GARRE1	5.39e-06	191	72	7	int:FAM120C
Interaction	SF3A1 interactions	PTPN12 CEBPA CEBPB TRIM67 ASXL3 BRD4 YLPM1 ACIN1 ZNF318 SRCAP	6.48e-06	471	72	10	int:SF3A1
Interaction	CRK interactions	TRIM67 BICRA BRD4 PHACTR4 SYN1 CBLB WASF1 VPS37B GAB1	6.60e-06	370	72	9	int:CRK
Interaction	SNRPG interactions	FOXO1 CEBPA CEBPB TRIM67 RC3H1 BRD4 SMN1	6.82e-06	198	72	7	int:SNRPG
Interaction	ATXN2L interactions	CEBPA CEBPB TRIM67 CPSF6 RC3H1 BRD4 FIP1L1 PTPN23	8.13e-06	286	72	8	int:ATXN2L
Interaction	SMARCC1 interactions	CEBPA CEBPB TRIM67 CPSF6 BICRA RC3H1 BRD4 YLPM1 SRCAP	8.90e-06	384	72	9	int:SMARCC1
Interaction	SNRPF interactions	CEBPA TRIM67 CPSF6 PHF3 YLPM1 ACIN1 SMN1 RPRD2 SCAF4	9.09e-06	385	72	9	int:SNRPF
Interaction	HNRNPUL2 interactions	CEBPA TRIM67 CPSF6 RC3H1 BRD4 ACIN1 IRF2BPL TNRC6C	9.23e-06	291	72	8	int:HNRNPUL2
Interaction	GNL2 interactions	MST1R ZC3H10 TRIM67 MAP1A RC3H1 BRD4 ZBTB47 AFDN PRR11	9.28e-06	386	72	9	int:GNL2
Interaction	DHX8 interactions	CEBPB TRIM67 CPSF6 MAPKAPK2 YLPM1 FIP1L1 RPRD2 ZNF318	9.46e-06	292	72	8	int:DHX8
Interaction	HCFC1 interactions	CEBPA SETD1B CEBPB TRIM67 CPSF6 ASXL3 BRD4 RERE	9.70e-06	293	72	8	int:HCFC1
Interaction	VASP interactions	CEBPA CEBPB TRIM67 MAP1A XIRP2 PHACTR4 PTPN23 FYB1	9.94e-06	294	72	8	int:VASP
Interaction	CDKN2AIP interactions	ZC3H10 CEBPA CEBPB TRIM67 BRD4 ADD1	1.08e-05	140	72	6	int:CDKN2AIP
Interaction	WDR82 interactions	CEBPA SETD1B CEBPB TRIM67 CPSF6 BRD4 FIP1L1	1.10e-05	213	72	7	int:WDR82
Interaction	BRIX1 interactions	MST1R ZC3H10 CEBPB TRIM67 RC3H1 BRD4 ZBTB47 PRR11	1.15e-05	300	72	8	int:BRIX1
Interaction	ACIN1 interactions	CEBPA CEBPB TRIM67 CPSF6 MAPKAPK2 BRD4 ACIN1 SCAF4	1.18e-05	301	72	8	int:ACIN1
Interaction	YWHAB interactions	FOXO1 MST1R GRID2IP CEBPB TRIM67 CPSF6 PHF3 RC3H1 PHACTR4 AFDN HES1 WASF1 GARRE1 GAB1	1.18e-05	1014	72	14	int:YWHAB
Interaction	RBBP6 interactions	FOXO1 TRIM67 CPSF6 MAPKAPK2 BRD4 ACIN1 SMN1	1.20e-05	216	72	7	int:RBBP6
Interaction	TP63 interactions	SETD1B CEBPB MAP1A CPSF6 WT1 RNF38 PTPN23 SCAF4	1.27e-05	304	72	8	int:TP63
Interaction	MEN1 interactions	PRR12 SETD1B FAM120C CPSF6 YLPM1 WT1 FIP1L1 ACIN1 AFDN SMN1 IRF2BPL RERE SRCAP CBLB	1.40e-05	1029	72	14	int:MEN1
Interaction	FUS interactions	FOXO1 CEBPA TRIM67 CPSF6 PHF3 RC3H1 BRD4 YLPM1 ACIN1 SMN1 RPRD2 SCAF4	1.40e-05	757	72	12	int:FUS
Interaction	CASP1 interactions	CEBPA CEBPB TRIM67 BRD4 GAB1	1.41e-05	86	72	5	int:CASP1
Interaction	ZC3H4 interactions	CEBPB TRIM67 CPSF6 MAPKAPK2 RC3H1 BRD4	1.43e-05	147	72	6	int:ZC3H4
Interaction	ITSN2 interactions	CPSF6 YLPM1 WIPF3 SYN1 TNRC6C CBLB	1.43e-05	147	72	6	int:ITSN2
Interaction	SUPT5H interactions	CEBPB TRIM67 CPSF6 PHF3 BICRA BRD4 ACIN1 RPRD2 SCAF4	1.44e-05	408	72	9	int:SUPT5H
Interaction	SNRPB interactions	TRIM67 CPSF6 PHF3 BRD4 YLPM1 ACIN1 SMN1 RPRD2 ZNF318 SCAF4	1.46e-05	517	72	10	int:SNRPB
Interaction	FIP1L1 interactions	CEBPA CEBPB TRIM67 CPSF6 RC3H1 BRD4 FIP1L1	1.57e-05	225	72	7	int:FIP1L1
Interaction	CNOT9 interactions	TRIM67 FAM120C RC3H1 RPRD2 ZNF318 TNRC6C GARRE1	1.86e-05	231	72	7	int:CNOT9
Interaction	RFC1 interactions	ZC3H10 CEBPA CEBPB TRIM67 MAPKAPK2 RC3H1 BRD4	1.86e-05	231	72	7	int:RFC1
Interaction	BUB3 interactions	CEBPA SETD1B CEBPB TRIM67 ASXL3 BRD4 RERE	1.91e-05	232	72	7	int:BUB3
Interaction	CTR9 interactions	CEBPA CEBPB TRIM67 CPSF6 BRD4 NAF1 RPRD2	1.96e-05	233	72	7	int:CTR9
Interaction	POLR2A interactions	CEBPA SETD1B CEBPB TRIM67 CPSF6 BRD4 SMN1 HES1 RPRD2 SCAF4	1.99e-05	536	72	10	int:POLR2A
Interaction	RNPS1 interactions	CEBPA CEBPB TRIM67 CPSF6 BICRA NAF1 FIP1L1 ACIN1 SCAF4	1.99e-05	425	72	9	int:RNPS1
Interaction	CPEB4 interactions	TRIM66 TRIM67 FAM120C RC3H1 TNRC6C GARRE1	2.00e-05	156	72	6	int:CPEB4
Interaction	DDX17 interactions	CEBPA CEBPB TRIM67 CPSF6 RC3H1 BRD4 YLPM1 ACIN1 SMN1	2.03e-05	426	72	9	int:DDX17
Interaction	EDF1 interactions	CEBPA CEBPB TRIM67 RC3H1 BRD4	2.06e-05	93	72	5	int:EDF1
Interaction	SLC25A5 interactions	FOXO1 CEBPA TRIM67 ASXL3 RC3H1 BRD4 PPM1E ACIN1 SKI	2.23e-05	431	72	9	int:SLC25A5
Interaction	PFN2 interactions	MYPOP GRID2IP TRIM67 SYN1 SMN1 WASF1	2.23e-05	159	72	6	int:PFN2
Interaction	HP1BP3 interactions	FOXO1 MST1R CEBPA CEBPB TRIM67 BRD4 ZBTB47 PRR11	2.24e-05	329	72	8	int:HP1BP3
Interaction	YLPM1 interactions	CEBPB TRIM67 CPSF6 MAPKAPK2 BRD4 YLPM1	2.31e-05	160	72	6	int:YLPM1
Interaction	PCNP interactions	MST1R CEBPA CEBPB TRIM67 BRD4	2.40e-05	96	72	5	int:PCNP
Interaction	PHF6 interactions	ZC3H10 CEBPA TRIM67 RC3H1 BRD4 ZNF318	2.48e-05	162	72	6	int:PHF6
Interaction	SAFB interactions	FOXO1 CEBPA TRIM67 CPSF6 MAPKAPK2 BRD4 ACIN1	2.64e-05	244	72	7	int:SAFB
Interaction	ERH interactions	CEBPB TRIM67 CPSF6 RC3H1 BRD4 FIP1L1 SMN1	2.71e-05	245	72	7	int:ERH
Interaction	YTHDF3 interactions	FOXO1 CEBPB TRIM67 FAM120C RC3H1 TNRC6C GARRE1	2.78e-05	246	72	7	int:YTHDF3
Interaction	LASP1 interactions	FOXO1 ZC3H10 CEBPA CEBPB TRIM67 BRD4 RNF38	2.85e-05	247	72	7	int:LASP1
Interaction	PFDN2 interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 ASXL3 RPRD2	2.85e-05	247	72	7	int:PFDN2
Interaction	C11orf58 interactions	FOXO1 CEBPA TRIM67 BRD4 ACIN1	3.07e-05	101	72	5	int:C11orf58
Interaction	DDX5 interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 MAPKAPK2 BRD4 SYN1 SMN1 SKI	3.26e-05	568	72	10	int:DDX5
Interaction	PRPF39 interactions	CEBPA CEBPB TRIM67 ZNF318	3.30e-05	51	72	4	int:PRPF39
Interaction	CRX interactions	PRR12 ZC3H10 MYO15B BICRA FBRSL1 RERE SKI	3.41e-05	254	72	7	int:CRX
Interaction	SNRPB2 interactions	CEBPA CEBPB TRIM67 CPSF6 RC3H1 ACIN1 SMN1	3.50e-05	255	72	7	int:SNRPB2
Interaction	PABPC1 interactions	FOXO1 CEBPA CEBPB TRIM67 CPSF6 MAPKAPK2 RC3H1 BRD4 TNRC6C SKI GAB1	3.56e-05	699	72	11	int:PABPC1
Interaction	ZNF512 interactions	MST1R ZC3H10 TRIM67 RC3H1 BRD4 ZBTB47 PRR11	3.58e-05	256	72	7	int:ZNF512
Interaction	SMARCC2 interactions	CEBPA CEBPB TRIM67 CPSF6 BICRA BRD4 YLPM1 SRCAP	3.69e-05	353	72	8	int:SMARCC2
Interaction	RBMX interactions	MYPOP CEBPA CEBPB TRIM67 CPSF6 ASXL3 RC3H1 BRD4 YLPM1	3.77e-05	461	72	9	int:RBMX
Interaction	PES1 interactions	CEBPA CEBPB TRIM67 RC3H1 BRD4 NAF1 PRR11	3.77e-05	258	72	7	int:PES1
Interaction	DIDO1 interactions	CEBPA TRIM67 MAP1A CPSF6 MAPKAPK2 BRD4	3.95e-05	176	72	6	int:DIDO1
Interaction	ZNF638 interactions	ZC3H10 JPH4 CEBPB TRIM67 CPSF6 MAPKAPK2 AFDN	4.05e-05	261	72	7	int:ZNF638
Interaction	MTREX interactions	CEBPA CEBPB TRIM67 CPSF6 RC3H1 BRD4 SYVN1	4.15e-05	262	72	7	int:MTREX
GeneFamily	Ring finger proteins	TRIM67 RC3H1 RNF44 RNF38 SYVN1 CBLB	8.42e-05	275	48	6	58
GeneFamily	Basic leucine zipper proteins\|CCAAT/enhancer binding proteins	CEBPA CEBPB	1.03e-04	6	48	2	1165
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN12 PTPN23	1.03e-03	18	48	2	812
GeneFamily	Zinc fingers CCCH-type	ZC3H10 RC3H1	3.88e-03	35	48	2	73
GeneFamily	Basic leucine zipper proteins	CEBPA CEBPB	7.50e-03	49	48	2	506
GeneFamily	PDZ domain containing	SHANK1 GRID2IP AFDN	7.64e-03	152	48	3	1220
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MYPOP RERE	8.73e-03	53	48	2	532
Coexpression	GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN	FOXO1 PTPN12 FAM120C PHF3 ZNF652 RNF38 IRF2BPL SYVN1	8.78e-08	200	73	8	M7353
Coexpression	GSE21379_WT_VS_SAP_KO_CD4_TCELL_DN	FOXO1 RC3H1 PPM1E HES1 PRR11 SYVN1 CBLB	1.40e-06	199	73	7	M7511
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP	FOXO1 SETD1B ZNF652 RNF44 RNF38 ZNF318 FYB1	1.44e-06	200	73	7	M4524
Coexpression	GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP	FOXO1 ZNF652 RC3H1 IRF2BPL SKI VPS37B ADD1	1.44e-06	200	73	7	M9258
Coexpression	GSE12366_GC_VS_NAIVE_BCELL_DN	PRR12 SETD1B RNF44 HES1 SKI VPS37B	1.77e-05	195	73	6	M3170
Coexpression	GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP	FOXO1 PDE4A PPM1E HES1 ADD1	5.73e-05	147	73	5	M6765
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SETD1B RC3H1 PTPN23 AFDN RPRD2	7.89e-06	166	73	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4A PHF3 PPM1E AFDN IRF2BPL	9.64e-06	173	73	5	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	IPF-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	HOXA3 PDE4A WIPF3 SKI GAB1	1.02e-05	175	73	5	b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
Drug	6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	DNHD1 PRR12 BRD4 PTPN23 RERE SRCAP SKI	4.30e-08	104	73	7	ctd:C000595015
Drug	Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A	PDE4A MAP1A MAPKAPK2 ZNF318 SRCAP ADD1	3.54e-05	192	73	6	2081_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	FOXO1 MAPKAPK2 PHACTR4 ACIN1 AFDN GAB1	3.86e-05	195	73	6	2942_UP
Drug	Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	TRIM66 PDE4A BICRA ZNF652 BRD4 VPS37B	3.86e-05	195	73	6	3409_DN
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A	PRRG1 PDE4A MAPKAPK2 PHF3 BICRA SRCAP	3.97e-05	196	73	6	3217_DN
Drug	Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	PDE4A PHF3 ZNF652 PHACTR4 ZNF318 SCAF4	3.97e-05	196	73	6	6236_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	CPSF6 PHF3 BICRA ZNF652 YLPM1 RPRD2	4.09e-05	197	73	6	3404_DN
Drug	Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A	PRRG1 PHF3 ZNF652 PHACTR4 YLPM1 SRCAP	4.09e-05	197	73	6	6792_DN
Drug	Roxithromycin [80214-83-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A	PRRG1 BICRA ZNF652 YLPM1 ADD1 SCAF4	4.33e-05	199	73	6	4778_DN
Drug	Alfadolone acetate [23930-37-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	TRIM66 PDE4A PTPN12 MAP1A ZNF318 SCAF4	4.33e-05	199	73	6	7262_DN
Drug	Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A	PDE4A ZBTB39 CEBPA MAPKAPK2 BICRA ZNF318	4.33e-05	199	73	6	7219_DN
Disease	platelet crit	FOXO1 PDE4A CEBPA MAP1A YLPM1 RPRD2 ZNF318 RERE SKI FYB1 EPG5	1.86e-05	952	72	11	EFO_0007985
Disease	triglyceride measurement, coronary artery disease	SETD1B FBRSL1	3.51e-05	4	72	2	EFO_0001645, EFO_0004530
Disease	Chromosome 1p36 Deletion Syndrome	RERE SKI	5.84e-05	5	72	2	C1842870
Disease	Acute Promyelocytic Leukemia	CEBPA WT1 FIP1L1	1.96e-04	46	72	3	C0023487
Disease	Osteosarcoma	MST1R BRD4 WT1	2.09e-04	47	72	3	C0029463
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	SETD1B ZNF652 FBRSL1	2.37e-04	49	72	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	Tinnitus	FBRSL1 FIP1L1 ZNF318 CBLB	2.93e-04	130	72	4	HP_0000360
Disease	Malignant tumor of colon	PTPN12 BRD4 WT1 HES1	6.28e-04	159	72	4	C0007102
Disease	mean reticulocyte volume	FOXO1 CEBPA ZNF652 BRD4 FBRSL1 WT1 AFDN ZNF318	7.25e-04	799	72	8	EFO_0010701
Disease	Intellectual Disability	PRR12 IQSEC3 BRD4 ACIN1 PTPN23 WASF1	7.85e-04	447	72	6	C3714756
Disease	Diuretic use measurement	CPSF6 ZNF652 WT1 ZNF318	7.89e-04	169	72	4	EFO_0009928
Disease	Leukemia, Myelocytic, Acute	FOXO1 CEBPA WT1 CBLB	8.61e-04	173	72	4	C0023467
Disease	Tourette syndrome, schizophrenia	PHF3 RERE	8.76e-04	18	72	2	EFO_0004895, MONDO_0005090
Disease	feeling miserable measurement	MST1R RC3H1 RERE	9.64e-04	79	72	3	EFO_0009598
Disease	Glioblastoma	BRD4 WT1 HES1	9.64e-04	79	72	3	C0017636
Disease	Giant Cell Glioblastoma	BRD4 WT1 HES1	1.15e-03	84	72	3	C0334588
Disease	pain	IQSEC3 CPSF6 RPRD2 RERE	1.37e-03	196	72	4	EFO_0003843
Disease	corpus callosum volume measurement	MST1R WNK2 ADD1	1.90e-03	100	72	3	EFO_0010299
Disease	neurotic disorder	ASXL3 YLPM1 RERE	1.96e-03	101	72	3	EFO_0004257
Disease	Subfertility, Female	CEBPA CEBPB	2.13e-03	28	72	2	C0341869
Disease	Sterility, Postpartum	CEBPA CEBPB	2.13e-03	28	72	2	C0038279
Disease	Female sterility	CEBPA CEBPB	2.13e-03	28	72	2	C0917730
Disease	Female infertility	CEBPA CEBPB	2.13e-03	28	72	2	C0021361

Protein segments in the cluster

Peptide	Gene	Start	Entry
QGIPRPLHPPPPPPV	ACIN1	1111	Q9UKV3
VHPMQPLPPQPPLPP	AMELX	146	Q99217
RTDLPPPPPPPPVHY	AFDN	1361	P55196
PQPPLALHPTKPPVP	EPG5	1506	Q9HCE0
PPPPQPRGLLPTHVP	FBRSL1	301	Q9HCM7
QSQPPPPLPPPPHPS	BRD4	951	O60885
PIPPCPPPPQPHLLH	DNHD1	886	Q96M86
NKALVHPPPPPPPPP	ASXL3	2011	Q9C0F0
PPYSRLPPPPQPHPS	RC3H1	736	Q5TC82
FPSPGPPQPPHPPLA	PTPN23	1036	Q9H3S7
PPQPPHPPLAYGPAP	PTPN23	1041	Q9H3S7
PSPPPQSSPPPQPHP	CRELD1	31	Q96HD1
PGHDPPPLPQPDPRP	MAP1A	2556	P78559
APAPPPQPPTPALPH	MAPKAPK2	16	P49137
PQPPTPALPHPPAQP	MAPKAPK2	21	P49137
QPPSLGEPPLHPPPP	HOXA3	81	O43365
GEPPLHPPPPQAAPP	HOXA3	86	O43365
TIPDIPPPRPPKPHP	GAB1	336	Q13480
GHSDPPTPPPPLPLP	JPH4	166	Q96JJ6
ALPPSLPPPPPPARH	CBLB	816	Q13191
PPPPPPPLGPHSNRT	IRF2BPL	596	Q9H1B7
PRPSQPPPPPVPHLQ	PDE4A	316	P27815
PPGAPPTHLPPPPFL	FIP1L1	361	Q6UN15
SLPPPPPSHPASQPP	FYB1	391	O15117
VKVTHQPPLPPPPPP	IQSEC3	1141	Q9UPP2
PLPTHIPPEPPRTPP	PHACTR4	346	Q8IZ21
HSAVPPPPPQLPPLP	PPM1E	111	Q8WY54
IAHTPPPPPAPPLPL	MYO15B	1186	Q96JP2
APPQPPPPGPLSQHP	FOXO1	121	Q12778
PPPGPLSQHPPVPPA	FOXO1	126	Q12778
SDHIPPPPLSPPPPP	GRID2IP	746	A4D2P6
PPPPPPLPFHDAKPS	GRID2IP	756	A4D2P6
KPLTQLSHPVPPPPP	GRID2IP	786	A4D2P6
PPPAPHVNPAFFPPP	CPSF6	351	Q16630
QPGHPTPPPTPVPSP	CEBPA	221	P49715
HPPPPPPPPPAELKA	CEBPB	161	P17676
TPPQPPPPPAHKAAP	GARRE1	1036	O15063
SHPVQSLPPPPPPAP	F8A1;	216	P23610
QAQPGLHPPLPPPPP	FAM120C	96	Q9NX05
LSPPYRPVPSPHPPP	MAMLD1	336	Q13495
EPPLHPCPPPQAPPT	BICRA	816	Q9NZM4
LHLVPEPAAPPPPPP	BICRA	926	Q9NZM4
EHSGIPFPTPPPPPP	RPRD2	1261	Q5VT52
TVPPPQVPPHQPGPP	SCAF4	676	O95104
PITPPVSIPPPHTPP	SCAF4	746	O95104
HPAAAPPPPPPPQRL	ONECUT3	146	O60422
LPPALHGAPQPPPPP	ONECUT3	206	O60422
PGQPHPALQAPPPPP	HES1	156	Q14469
PQHAPFAPPPPLVPI	HES1	176	Q14469
QGPPPAPHPPPLLPQ	SYVN1	351	Q86TM6
APHPPPLLPQPPNFP	SYVN1	356	Q86TM6
QRPQPPPPPPGAHSP	SYN1	26	P17600
LVKQPPPPPPPPHLS	TNRC6C	1211	Q9HCJ0
QQPIPPPPYHPSLLP	RNF38	376	Q9H0F5
PPEPHPVPPILTPSP	PTPN12	356	Q05209
PPPPPPHLLSCWLPP	SMN1	221	Q16637
PPPPPPPPAHPAVTV	SETD1B	711	Q9UPS6
PPPAHPAVTVPPPPL	SETD1B	716	Q9UPS6
HLPPIPPPLPLLPPC	WIPF3	256	A6NGB9
PPPHPSPHPPLQPLT	RERE	816	Q9P2R6
PHIKPPPTTPIPQLP	RERE	926	Q9P2R6
PPDPPPPPRHLPTQF	PRR12	231	Q9ULL5
QSGPHQAAPPPPPPP	PRR12	1031	Q9ULL5
TQPPPHPSPLTPLPP	SRCAP	2966	Q6ZRS2
PPVLHLPAIQPPPPV	SKI	71	P12755
PLPPVPPPAVAAAPP	SHANK1	1601	Q9Y566
PPDQPAVPHPPPSTP	ADD1	601	P35611
PPPPPTPSQKPAHLL	XIRP2	2191	A4UGR9
AKHRLVQPPPPPPPP	TRIM67	246	Q6ZTA4
YILHPPPPAPPPQPT	RNF44	181	Q7L0R7
PPPAPPPQPTHMAPL	RNF44	186	Q7L0R7
PPPVSQPPPCNRLPP	UNC5CL	396	Q8IV45
PPPPPPPPHSFIKQE	WT1	61	P19544
FPPHLPPPLLPPPGF	PHF3	1831	Q92576
PLLPGLPQTLPPPPH	ZBTB47	711	Q9UFB7
PVLPPPPVHSSIPPP	YLPM1	1606	P49750
SLHLPQPPPPPPKTE	ZBTB39	196	O15060
PFPQHLNIITPPPPP	PRRG1	121	O14668
PVPPPPPPPATALQA	WASF1	351	Q92558
PLQPVPPHLPPYLAP	WNK2	751	Q9Y3S1
APPAAPPPPPPHLTP	ZC3H10	346	Q96K80
PPPPPPHLTPEITPL	ZC3H10	351	Q96K80
HLPIPPVPHLPPPPA	ZNF652	561	Q9Y2D9
LPPPPQQPHPPLPPS	TRIM66	471	O15016
PLPQRPPPRLPPHQP	VPS37B	266	Q9H9H4
TLPQPASHFPPPPPP	PRR11	176	Q96HE9
PPPHPPSANLVPLKP	MST1R	861	Q04912
PPPPPPVIPHPAAPS	ZNF318	1451	Q5VUA4
IPPHPKVPAPFSPPP	KIAA1522	601	Q9P206
MHNFPLRPPPPPPPP	NAF1	431	Q96HR8
PPLAQVAPSPPSPPP	MYPOP	231	Q86VE0
PRPPPAPLPPHDSPP	MYPOP	366	Q86VE0