Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal contextual conditioning behavior

GABRD DLG4 MMP9 ITM2B ZNF804A PREX1 KCNT1 PGBD5 RYR3

1.10e-07205569MP:0001469
MousePhenoabnormal temporal memory

GABRD DLG4 MMP9 ITM2B ZNF804A PREX1 KCNT1 PGBD5 RYR3

4.04e-07239569MP:0001468
MousePhenoabnormal associative learning

GABRD DLG4 MMP9 ITM2B ZNF804A PREX1 KCNT1 PGBD5 RYR3

2.35e-05393569MP:0002062
MousePhenoimpaired contextual conditioning behavior

MMP9 ITM2B ZNF804A KCNT1 PGBD5

5.08e-05101565MP:0009454
MousePhenoenlarged cerebellum

PDZD8 EFCAB3

9.41e-054562MP:0008914
DomainLamina-ass_polypeptide_CLAP1C

TOR1AIP2 TOR1AIP1

1.27e-052672IPR008662
DomainLAP1C

TOR1AIP2 TOR1AIP1

1.27e-052672PF05609
DomainTPR-like_helical_dom

CRNKL1 POLR1A NAPB COPS3 TRAPPC8 TTC6 CDC23

1.98e-05233677IPR011990
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

ASCC2 PDZD8 PFKFB2 TRAPPC8 PGM2 SMAD4

1.78e-0618369631932471
Pubmed

Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human beta-MSH(5-22) by dipeptidyl peptidase I and dipeptidyl peptidase IV.

DPP4 CTSC

3.88e-06269215985311
Pubmed

Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.

PREX1 PREX2

3.88e-06269220694145
Pubmed

Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis.

MMP9 NOS2

3.88e-06269217071581
Pubmed

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

PREX1 PREX2

3.88e-06269218334636
Pubmed

Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury.

MMP9 NOS2

3.88e-06269219443702
Pubmed

Schnurri-3 drives tumor growth and invasion in cancer cells expressing interleukin-13 receptor alpha 2.

HIVEP3 IL13RA2

3.88e-06269237963919
Pubmed

P-Rex1 and P-Rex2 RacGEFs and cancer.

PREX1 PREX2

3.88e-06269228710285
Pubmed

Slo2 sodium-activated K+ channels bind to the PDZ domain of PSD-95.

DLG4 KCNT1

3.88e-06269214559234
Pubmed

Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor.

TPP2 RYR3

3.88e-06269223818952
Pubmed

Hypoxia enhances gene expression of inducible nitric oxide synthase and matrix metalloproteinase-9 in ras/myc-transformed serum-free mouse embryo cells under simulated inflammatory and infectious conditions.

MMP9 NOS2

3.88e-06269218474440
Pubmed

Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cells.

MMP9 SMAD4

3.88e-06269217151782
Pubmed

The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4.

ZBTB4 HIPK2

3.88e-06269219448668
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CRNKL1 POLR1A ANKRD11 ASCC2 COPS3 TTC6 RYR3 CDC23

6.40e-0649769836774506
Pubmed

A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding.

TOR1AIP2 TOR1AIP1

1.16e-05369220861018
Pubmed

Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis.

MMP9 NOS2

1.16e-05369218597705
Pubmed

Expression Pattern of iNOS, BCL-2 and MMP-9 in the Hip Synovium Tissue of Patients with Osteoarthritis.

MMP9 NOS2

1.16e-05369233540799
Pubmed

Dynamic regulation of hepatic lipid metabolism by torsinA and its activators.

TOR1AIP2 TOR1AIP1

1.16e-05369238194265
Pubmed

Arresting a Torsin ATPase reshapes the endoplasmic reticulum.

TOR1AIP2 TOR1AIP1

1.16e-05369224275647
Pubmed

ATR signalling mediates the prosurvival function of phospho-NPM against PIDDosome mediated cell death.

NPM1 PIDD1

1.16e-05369232194167
Pubmed

Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.

MMP9 NOS2

2.32e-05469223016931
Pubmed

Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.

DLG4 ZZEF1

2.32e-05469225709106
Pubmed

Characterization of hematopoietic progenitor mobilization in protease-deficient mice.

CTSC MMP9

2.32e-05469215010367
Pubmed

The mechanism of Torsin ATPase activation.

TOR1AIP2 TOR1AIP1

2.32e-05469225352667
Pubmed

Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.

PLGLA PLGLB1

2.32e-0546921986355
Pubmed

Orostachys japonicus inhibits the expression of MMP-2 and MMP-9 mRNA and modulates the expression of iNOS and COX-2 genes in human PMA-differentiated THP-1 cells via inhibition of NF-κB and MAPK activation.

MMP9 NOS2

2.32e-05469225760396
Pubmed

NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism.

NPM1 NOS2

2.32e-05469223338972
Pubmed

Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis.

PLGLA PLGLB1

2.32e-0546921554698
Pubmed

Genetic polymorphisms of macrophage-mediators in Guillain-Barré syndrome.

MMP9 NOS2

2.32e-05469217761309
Pubmed

Rho GEFs and cancer: linking gene expression and metastatic dissemination.

PREX1 PREX2

2.32e-05469223033535
Pubmed

IL-6/NOS2 inflammatory signals regulate MMP-9 and MMP-2 activity and disease outcome in nasopharyngeal carcinoma patients.

MMP9 NOS2

2.32e-05469226453114
Pubmed

Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation.

NPM1 KAT2B

2.32e-05469229746960
Pubmed

The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein.

TOR1AIP2 TOR1AIP1

3.86e-05569215767459
Pubmed

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.

NPM1 PIDD1

3.86e-05569228432080
Pubmed

Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletion.

TOR1AIP2 TOR1AIP1

3.86e-05569219651773
Pubmed

The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.

KAT2B SMAD4

3.86e-05569224739390
Pubmed

Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.

MMP9 SMAD4

5.79e-05669224340014
Pubmed

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

PREX1 PREX2

5.79e-05669225538043
Pubmed

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.

MMP9 PREX1

5.79e-05669220650312
Pubmed

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.

KAT2B HIPK2

5.79e-05669216917507
Pubmed

Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope.

TOR1AIP2 TOR1AIP1

5.79e-05669216364897
Pubmed

The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation.

KAT2B POLR1A

8.09e-05769223667505
Pubmed

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.

PREX1 PREX2

8.09e-05769221178006
Pubmed

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.

PREX1 PREX2

8.09e-05769217565979
Pubmed

Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.

HIPK2 SMAD4

8.09e-05769212874272
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

LIG1 NBAS CRNKL1 PRPF40A PGM2

8.70e-0522569525277244
Pubmed

Regulation of Torsin ATPases by LAP1 and LULL1.

TOR1AIP2 TOR1AIP1

1.08e-04869223569223
Pubmed

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

PREX1 PREX2

1.08e-04869224659802
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NPM1 CRNKL1 POLR1A WDR75 BAZ1A COPS3 MMP9 ITM2B PRPF40A TOR1AIP1 MYBPC1

1.08e-041425691130948266
Pubmed

Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas.

KAT2B SMAD4

1.38e-04969221596989
Pubmed

Polymorphisms in angiogenesis-related genes and prostate cancer.

MMP9 NOS2

1.38e-04969218398039
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TOR1AIP2 NPM1 NBAS WDR75 ANKRD11 ASCC2 PDZD8 TRAPPC8 ITM2B PRPF40A TOR1AIP1

1.57e-041487691133957083
Pubmed

Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis.

IL13RA2 MMP9

1.73e-041069220181883
Pubmed

Analysis of cDNA sequences from mouse testis.

BUB1 ITM2B

1.73e-04106928000140
Pubmed

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.

KAT2B NAPB HIPK2 CDC23

1.98e-0414469430585266
Pubmed

The LMO2 oncogene regulates DNA replication in hematopoietic cells.

BAZ1A HIPK2 ITM2B

2.13e-045869326764384
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

TOR1AIP2 NPM1 POGLUT1 POLR1A BUB1 ASCC2 DLG4 COPS3 PGM2 MYBPC1

2.25e-041293691015342556
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TOR1AIP2 NPM1 TPP2 CTU2 POGLUT1 WDR75 BAZ1A CTSC TOR1AIP1 PGM2

2.31e-041297691033545068
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

NPM1 LIG1 COPS3 CDC23

2.49e-0415369426365490
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

TOR1AIP2 NPM1 CRNKL1 POLR1A WDR75 BAZ1A PRPF40A TOR1AIP1

2.70e-0484769835850772
Pubmed

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons.

HIPK2 SMAD4

3.48e-041469217159989
Pubmed

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.

TOR1AIP2 TOR1AIP1

4.01e-041569220457914
Pubmed

Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.

KAT2B TAF5

4.01e-041569212601814
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

TOR1AIP2 NBAS ITM2B TOR1AIP1

4.24e-0417669428692057
Pubmed

Liver X receptor β regulates the development of the dentate gyrus and autistic-like behavior in the mouse.

DLG4 SMAD4

4.57e-041669229507213
Pubmed

Histone-like TAFs within the PCAF histone acetylase complex.

KAT2B TAF5

5.18e-04176929674425
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

HIVEP3 NPM1 TPP2 LIG1 TTC6

5.31e-0433369532665550
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

TOR1AIP2 NPM1 LIG1 CRNKL1 POGLUT1 CTSC PDZD8 ITM2B PRPF40A SMAD4

5.60e-041451691030550785
Pubmed

Murine transcription factor Math6 is a regulator of placenta development.

MMP9 KLRG1

5.81e-041869230301918
Pubmed

Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.

HIPK2 DLG4

6.49e-041969221957238
Pubmed

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.

NOS2 PTPRT

6.49e-041969224315451
Pubmed

Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

KAT2B TAF5

7.20e-042069210373431
Pubmed

Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1.

NPM1 CDC23

7.20e-042069218162579
Pubmed

Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.

GABRD DLG4

7.95e-042169225708312
Pubmed

Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

MMP9 NOS2 SMAD4

8.80e-049469320346360
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NPM1 CRNKL1 POLR1A WDR75 BAZ1A PRPF40A TOR1AIP1 CDC23

9.39e-04102469824711643
Pubmed

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

HIVEP3 ZBTB41

9.55e-042369224925725
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GABRD PPP4R3B CRNKL1 NAPB ZBTB4 PDZD8 DLG4 PREX1 RYR3

9.64e-04128569935914814
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NPM1 WDR75 BAZ1A ANKRD11 TAF5 PRPF40A TOR1AIP1 CDC23 SMAD4

1.01e-03129469930804502
Pubmed

Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.

MMP9 NOS2

1.04e-032469228237967
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

IQGAP2 BUB1 KLRG1 PREX1

1.10e-0322769426410627
Pubmed

The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.

NPM1 PRPF40A

1.13e-032569215456888
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

KAT2B DLG4

1.42e-032869231600191
Pubmed

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

KAT2B TAF5

1.42e-032869219114550
Pubmed

The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model.

MMP9 NOS2

1.52e-032969237948457
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

PDZD8 PRPF40A

1.52e-032969221834987
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

NPM1 CRNKL1 PRPF40A

1.54e-0311469331553912
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TOR1AIP2 NPM1 KAT2B DLG4 TAF5 ZZEF1 PRPF40A CDC23

1.62e-03111669831753913
Pubmed

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

KAT2B TAF5

1.63e-033069218206972
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

NPM1 PPP4R3B POLR1A ASCC2 CDC23

1.83e-0344069534244565
Pubmed

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.

TOR1AIP2 COPS3

1.85e-033269216964240
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NPM1 TPP2 CRNKL1 POLR1A WDR75 PRPF40A

1.88e-0365369622586326
Pubmed

Ubiquitin chain elongation requires E3-dependent tracking of the emerging conjugate.

BUB1 CDC23

1.97e-033369225306918
Pubmed

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.

KAT2B TAF5

1.97e-033369211564863
Cytoband16q24.3

CTU2 ANKRD11

2.81e-035269216q24.3
GeneFamilyPDZ domain containing

PDZD8 DLG4 PREX1 PREX2

3.82e-041524141220
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

IQGAP2 BAZ1A ZBTB4 ANKRD11 HIPK2 PRPF40A

6.60e-0719969653ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP4 IQGAP2 PCOLCE2 ZNF804A RYR3

6.34e-06168695fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP4 IQGAP2 PCOLCE2 ZNF804A RYR3

6.34e-06168695e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF804B PCOLCE2 ZNF804A DNAH14 TTC6

6.90e-06171695fdd96c6fe850bd10e1e0d0f18c4401f8348b7d2c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ELAPOR2 ELL2 PIK3C2G DNAH14 TTC6

1.18e-0519169534cc997e4e5c727495f321e6807a84aa124da486
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

BAZ1A ZBTB4 ANKRD11 HIPK2 PRPF40A

1.40e-0519869576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

IQGAP2 BAZ1A ANKRD11 HIPK2 PRPF40A

1.44e-05199695fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IQGAP2 CTSC PCOLCE2 ZNF804A PREX1

1.44e-051996957ee2805fd9143eba11bf6832267b62189683608b
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQGAP2 GPR141 KLRG1 PGBD5

7.40e-05144694013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 IQGAP2 KLRG1 PGBD5

8.67e-051506947290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCellLPS_only-Hematopoietic_Mast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 IQGAP2 KLRG1 PGBD5

8.67e-051506942c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 IQGAP2 GPR141 MMP9

8.90e-051516943105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PIDD1 MMP9 ZNF804A RYR3

9.60e-05154694df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

9.84e-0515569490e629681a72baacc7981b82883866a487638dbc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

9.84e-05155694e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

9.84e-051556945a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.09e-04159694fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.09e-04159694aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.09e-041596948bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRD IQGAP2 ZNF804A MYBPC1

1.19e-04163694db6b7ce6f7221bb73c5e650ac51cdd5d7ef00675
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRD IQGAP2 ZNF804A MYBPC1

1.22e-04164694f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRD IQGAP2 ZNF804A MYBPC1

1.25e-04165694d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 PIK3C2G PCOLCE2 RYR3

1.31e-04167694a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.34e-04168694315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

LIG1 MEIG1 BUB1 PHF7

1.40e-041706945319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POGLUT1 NAPB PCOLCE2 TAF5

1.47e-04172694574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.47e-041726946c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POGLUT1 NAPB PCOLCE2 TAF5

1.47e-041726941627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.47e-04172694381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 IQGAP2 GPR141 PREX2

1.50e-04173694c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 PIK3C2G PTPRT RYR3

1.54e-04174694f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G PTPRT DNAH14 RYR3

1.54e-04174694ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.54e-04174694dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 PCOLCE2 ZNF804A RYR3

1.57e-04175694a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.64e-041776944d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.68e-04178694edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 PTPRT PGBD5 RYR3

1.68e-04178694a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.71e-041796947394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.79e-041816945bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.79e-041816948e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRD DLG4 KCNT1 RYR3

1.82e-04182694d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

DPP4 IQGAP2 GPR141 PREX1

1.82e-04182694257a7847917b6ea1d60608183d90300bfd028758
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

NBAS ELL2 GPR141 RYR3

1.82e-0418269468a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRD DLG4 KCNT1 RYR3

1.82e-041826946cde859edfe7607bd7ada89d20258413d06f4207
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-04183694fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-041836943c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-04183694612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-04183694848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-04183694eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.86e-041836949c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

NBAS ELL2 PREX1 PGBD5

1.86e-04183694d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.90e-041846947294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.94e-041856949197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.94e-04185694ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

KAT2B IQGAP2 KLRG1 PREX1

1.94e-0418569402ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

1.94e-04185694b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIVEP3 IQGAP2 GPR141 HIPK2

1.98e-04186694fc0b488c201a32d829047b58460297df2818b45d
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

NBAS ELL2 GPR141 RYR3

1.98e-04186694def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 MEIG1 NAPB DLG4

1.98e-04186694f5468e03321ea2083e223eb0d92c3a9307039569
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 IQGAP2 CTSC ITM2B

1.98e-04186694c7e2134454ab5d0885050dd1bb3c3bd15bf497ac
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPP4 CTSC PFKFB2 PGM2

2.02e-041876946ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TOR1AIP2 PCOLCE2 ZZEF1 CDC23

2.02e-041876944527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPP4 ELAPOR2 PIK3C2G PFKFB2

2.02e-041876945df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIVEP3 IQGAP2 GPR141 HIPK2

2.02e-041876946981b856187a2e689260ecb7d0a1193a374ee9b9
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PCOLCE2 ZNF804A RYR3

2.02e-0418769424c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KAT2B HIPK2 PREX1 PREX2

2.06e-04188694505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RAB36 LIG1 BUB1 PHF7

2.15e-04190694250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

DPP4 IQGAP2 ITM2B KLRG1

2.15e-0419069485cf147f2baf2e575073b4edab57c7809475268a
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDZD8 PCOLCE2 PFKFB2 MMP9

2.19e-041916946c1283d51a845cff67ed5e500f7e944165297b53
ToppCellCTRL-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

DPP4 KAT2B IQGAP2 ITM2B

2.19e-0419169432381d353e40bce77a5b63c7bdbe360d27327d86
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDZD8 PCOLCE2 PFKFB2 MMP9

2.24e-0419269486d561c30554ff04c21801d4aaf8e3c9efe49af4
ToppCellCOVID-19_Severe-Myeloid_G-immature_Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

PDZD8 PCOLCE2 PFKFB2 MMP9

2.24e-04192694303deb68da2e4a75e6ee5a79478182a8bc41c7c5
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ELAPOR2 PIK3C2G DNAH14 TTC6

2.24e-04192694fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELL2 IQGAP2 RYR3 MYBPC1

2.28e-041936941aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CTSC HIPK2 PCOLCE2 ZNF804A

2.33e-0419469469cf7c989ac355c459db13f9d4267b55adc3c174
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

IQGAP2 CTSC GPR141 KLRG1

2.33e-04194694ecdfc27d06e363fb23f0309f26ef6404a89f14ec
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

KAT2B IQGAP2 KLRG1 PREX1

2.33e-041946945c1dca33f382f37a7deb23e573578343c3b54986
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MMP9 PTPRT DNAH14 RYR3

2.37e-04195694d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 IL13RA2 PREX1 PREX2

2.37e-0419569423ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MMP9 PTPRT DNAH14 RYR3

2.37e-0419569419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

KAT2B IQGAP2 BAZ1A ANKRD11

2.42e-041966947bced0cc2112697593c478fa291b8ed3941fb811
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPP4 CTSC MMP9 ITM2B

2.42e-04196694bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPP4 CTSC MMP9 ITM2B

2.42e-04196694072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 PREX1 PREX2 RYR3

2.42e-04196694adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellFLU-Healthy-2|FLU / Virus stimulation, Condition and Cluster

LIG1 CTSC BUB1 KLRG1

2.42e-041966940f2240a64a1cdd3147f2330f51c871cd0df8c055
ToppCell10x5'-bone_marrow-Lymphocytic_NK|bone_marrow / Manually curated celltypes from each tissue

IQGAP2 CTSC GPR141 HIPK2

2.42e-041966941868ad537b7f04cdad0a0c8282aadbc4f257a722
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

IQGAP2 CTSC ZNF804A PREX1

2.47e-04197694f18807124b91310fcd84238484a80ecdba684679
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 PREX1 PREX2 RYR3

2.52e-0419869407701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 IL13RA2 PREX1 PREX2

2.52e-0419869492416e65a0dc1a4bf931833407620ea05d362f56
ToppCellImmune|World / Lineage, Cell type, age group and donor

IQGAP2 CTSC ZNF804A PREX1

2.52e-0419869465681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELL2 IQGAP2 CTSC MMP9

2.52e-04198694641e7be258303bb9782d19fcf8693f317581d3b8
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BAZ1A ZBTB4 ANKRD11 PRPF40A

2.56e-0419969461b1ed2db71b96157b92b7535d1955a4033098da
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Airway-Club|Control_saline / Treatment groups by lineage, cell group, cell type

IQGAP2 PIK3C2G TTC6 MYBPC1

2.56e-041996945cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

BAZ1A ANKRD11 HIPK2 PRPF40A

2.56e-04199694d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-CD4+_Tem|Multiple_Sclerosis / Disease, condition lineage and cell class

NPM1 DPP4 ITM2B KLRG1

2.56e-0419969479145d931a250c69a643936fea147e2bd50b4d6d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRD NAPB KCNT1 PTPRT

2.61e-042006942f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

PDZD8 PCOLCE2 PFKFB2 MMP9

2.61e-04200694cbe667eda1af222467df8bfa157aa22df488f133
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

IQGAP2 KLRG1 PGM2 PGBD5

2.61e-042006940b02f3ca3d8612ed7af46381195b0ed5591313cf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRD NAPB KCNT1 PTPRT

2.61e-04200694bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BAZ1A PFKFB2 MMP9 ITM2B

2.61e-042006946beabd5bad042d4d65c89c2f537c7376230f7c08
Diseasepulmonary hypertension (biomarker_via_orthology)

MMP9 NOS2 RYR3 SMAD4

2.99e-0580654DOID:6432 (biomarker_via_orthology)
Diseaserenal hypertension (implicated_via_orthology)

MMP9 NOS2

4.76e-055652DOID:1073 (implicated_via_orthology)
Diseasepulmonary emphysema (biomarker_via_orthology)

MMP9 NOS2

7.13e-056652DOID:9675 (biomarker_via_orthology)
DiseaseVasogenic Brain Edema

MMP9 NOS2

1.33e-048652C0750969
DiseaseCytotoxic Brain Edema

MMP9 NOS2

1.33e-048652C0750970
DiseaseCytotoxic Cerebral Edema

MMP9 NOS2

1.33e-048652C0472388
DiseaseVasogenic Cerebral Edema

MMP9 NOS2

1.33e-048652C0472387
DiseaseBrain Edema

MMP9 NOS2

1.33e-048652C1527311
DiseaseCerebral Edema

MMP9 NOS2

1.33e-048652C0006114
DiseaseMarfan Syndrome, Type I

MMP9 NOS2

1.70e-049652C4721845
DiseaseMarfan Syndrome

MMP9 NOS2

2.59e-0411652C0024796
Diseaselung disease (implicated_via_orthology)

MMP9 NOS2

3.67e-0413652DOID:850 (implicated_via_orthology)
Diseasebronchiolitis obliterans (is_marker_for)

MMP9 NOS2

3.67e-0413652DOID:2799 (is_marker_for)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP3 SMAD4

3.67e-0413652DOID:0050787 (implicated_via_orthology)
Diseasepulmonary hypertension (is_marker_for)

IL13RA2 MMP9 NOS2

3.86e-0464653DOID:6432 (is_marker_for)
DiseaseMood Disorders

GABRD KAT2B DLG4 ZNF804A

5.24e-04168654C0525045
DiseaseMalignant neoplasm of stomach

NPM1 NBAS CTSC PTPRT SMAD4

5.27e-04300655C0024623
Diseasephosphatidylethanolamine measurement

BAZ1A PCOLCE2 ZZEF1 RYR3

5.85e-04173654EFO_0010228
Diseaseesophagus squamous cell carcinoma (is_marker_for)

DPP4 KAT2B MMP9

5.91e-0474653DOID:3748 (is_marker_for)
DiseaseGastric ulcer

MMP9 NOS2

7.15e-0418652C0038358
DiseaseColorectal Carcinoma

HIVEP3 LIG1 BUB1 ZNF804A PREX2 PTPRT SMAD4

8.81e-04702657C0009402
DiseaseNeurodevelopmental Disorders

HIVEP3 ANKRD11 DLG4

1.15e-0393653C1535926
DiseaseSepticemia

MMP9 NOS2

1.28e-0324652C0036690
DiseaseSepsis

MMP9 NOS2

1.28e-0324652C0243026
DiseaseSevere Sepsis

MMP9 NOS2

1.28e-0324652C1719672
DiseaseIntrahepatic Cholangiocarcinoma

NOS2 SMAD4

1.28e-0324652C0345905
DiseaseUreteral obstruction

HIPK2 NOS2

1.28e-0324652C0041956
DiseasePyemia

MMP9 NOS2

1.28e-0324652C0034189
DiseaseExtrahepatic Cholangiocarcinoma

NOS2 SMAD4

1.28e-0324652C3805278
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

IQGAP2 CTSC PDZD8 PTPRT

1.33e-03216654EFO_0007925, EFO_0007927
Diseasecolon adenocarcinoma (is_marker_for)

MMP9 NOS2

1.39e-0325652DOID:234 (is_marker_for)
Diseaseinterstitial lung disease (is_marker_for)

MMP9 NOS2

1.39e-0325652DOID:3082 (is_marker_for)
DiseaseMalignant neoplasm of pancreas

BUB1 MMP9 SMAD4

1.50e-03102653C0346647
DiseaseCholangiocarcinoma

NOS2 SMAD4

1.50e-0326652C0206698
DiseaseRetinal Diseases

MMP9 NOS2

1.62e-0327652C0035309
Diseaselissencephaly (implicated_via_orthology)

WDR75 NOS2

1.62e-0327652DOID:0050453 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (biomarker_via_orthology)

MMP9 SMAD4

1.74e-0328652DOID:3083 (biomarker_via_orthology)
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

MMP9 NOS2

1.74e-0328652DOID:12236 (biomarker_via_orthology)
Diseaseobstructive sleep apnea (is_marker_for)

MMP9 NOS2

1.87e-0329652DOID:0050848 (is_marker_for)
Diseasemultiple myeloma

ELL2 ANKRD11 PREX1

1.96e-03112653EFO_0001378
Diseasepulmonary hypertension (is_implicated_in)

MMP9 NOS2

2.00e-0330652DOID:6432 (is_implicated_in)
Diseaseserum IgA measurement

ELL2 ASCC2

2.13e-0331652EFO_0004912

Protein segments in the cluster

PeptideGeneStartEntry
DKEFTCRAFQYHSKE

PLGLB1

56

Q02325
AVKSYKSYDFFRHDN

PFKFB2

81

O60825
KAYFDVKEYDRAAHF

CDC23

91

Q9UJX2
NYHEEKYRCEYLHNK

ELL2

606

O00472
KVYREDSAFDEYCNK

ANKRD11

806

Q6UB99
YCLKFAEYNSDLHQF

BUB1

71

O43683
KENGAYDAKHFLCYY

COPS3

171

Q9UNS2
QKHDFCYRLASFYEA

ASCC2

271

Q9H1I8
EIAFFCEEDYKNYKA

C2orf76

106

Q3KRA6
YCKVTNEIFRHYDDF

BAZ1A

26

Q9NRL2
HFKECTVEYELKYRN

IL13RA2

61

Q14627
NYLFGCELKADKDYH

NPM1

16

P06748
HRFCKNVFDRDYKAT

RAB36

141

O95755
ADYEKALRNFFYSCA

PIK3C2G

1006

O75747
YNEEHCFKFHKELAY

GPR141

161

Q7Z602
EDYFFQLKSQKRYHE

NOS2

1111

P35228
DHCKYKYLFNFRGVA

POGLUT1

261

Q8NBL1
THDVFQYREKAYFCQ

MMP9

661

P14780
DDYNFVRAYECFQHK

HIPK2

256

Q9H2X6
GFFIYRLCHDKETYK

ITM2B

216

Q9Y287
ESEYYKCANILEKFF

KAT2B

806

Q92831
CKHNSYEDAKAYGFK

KCNT1

766

Q5JUK3
NDKFCYGDITIHFKY

PDZD8

781

Q8NEN9
NNDYFEDLKKYCFHR

PGM2

226

Q96G03
YRHICYFQIDKKDCT

DPP4

381

P27487
VEYAFAHFNADYRKK

GABRD

326

O14764
KFEKFDVERDNYCRY

PCOLCE2

196

Q9UKZ9
KTEKSEFLNFFYNHC

PPP4R3B

456

Q5MIZ7
HASEQRYDAEFFKKF

NBAS

706

A2RRP1
DKEFTCRAFQYHSKE

PLGLA

56

Q15195
YSDCFFYHEKENQSL

ELAPOR2

671

A8MWY0
KENDTHCIDFHYYFS

PTPRT

96

O14522
FKFYVEDLKARYHDE

PRPF40A

661

O75400
ICRYDDKYSKYFISH

PGBD5

451

Q8N414
KYARFEEKHAYFAHA

CRNKL1

381

Q9BZJ0
KYGNHCYYFSVEEKD

KLRG1

81

Q96E93
AVAFEVYDDFLHYKK

CTSC

371

P53634
FYIRALFDYDKTKDC

DLG4

431

P78352
LTNKAKAYSHYQDCF

DNAH14

886

Q0VDD8
KFEHNDCLDKSYKCY

GLIPR1L1

76

Q6UWM5
KRFEEAAFTCEYKYD

LIG1

556

P18858
YNFFYKDKTGCIDFH

EFCAB3

56

Q8N7B9
FCRDCFKAFYVHKFR

CTU2

46

Q2VPK5
CFVFYSHLKNVKEVY

PIDD1

691

Q9HB75
FYYYNKQRECDDKEV

MEIG1

66

Q5JSS6
KSFFEKFHGDQECYY

TAF5

261

Q15542
LIFYKYCDHENAAFK

TOR1AIP2

376

Q8NFQ8
RLHYANCKAYNADFD

POLR1A

576

O95602
SQFFGEYKSFCDKHR

PHF7

131

Q9BWX1
TYQEFRKYFKEACNV

IQGAP2

1171

Q13576
KHFDHYIRFCFVKDE

KYAT1

391

Q16773
HVKYCQYAFDLKCDS

SMAD4

111

Q13485
KFCVYEEYCSNHEKA

PREX1

141

Q8TCU6
VKANFYCELCDKQYH

ZNF804B

51

A4D1E1
IFYKYCDHENAAFKD

TOR1AIP1

491

Q5JTV8
RAHFYYCLKQYELAE

TTC6

456

Q86TZ1
RNFYDDKKYTYTCLH

WDR75

231

Q8IWA0
DYHLYSEKFDLNKNC

RYR3

1351

Q15413
FKCTYCEEHFKSRFA

ZBTB41

491

Q5SVQ8
DNYEAHKKYYCSELQ

HIVEP3

656

Q5T1R4
VKQRAYRSHEFYKFC

TPP2

696

P29144
YRSHEFYKFCSLPEK

TPP2

701

P29144
YCEKVFALAEYRTKH

ZBTB4

341

Q9P1Z0
GTCFLHFKDKFRIYD

PREX2

106

Q70Z35
HFKDKFRIYDEYCSN

PREX2

111

Q70Z35
FRIYDEYCSNHEKAQ

PREX2

116

Q70Z35
SAKDYFFKAALCHFI

NAPB

201

Q9H115
FCAEEHFKRFEKYDK

ZZEF1

611

O43149
YDLAYSCYHTAKKDF

TRAPPC8

436

Q9Y2L5
VCDEAFAYNSYLAKH

ZNF468

331

Q5VIY5
NFYCELCDKQYYKHQ

ZNF804A

56

Q7Z570
LCDKQYYKHQEFDNH

ZNF804A

61

Q7Z570
FAGNYRCEVTYKDKF

MYBPC1

136

Q00872