Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF POTEE POTEI	8.86e-05	11	166	3	GO:0098973
GeneOntologyBiologicalProcess	postsynapse organization	ABL2 POTEF ROR2 DGKB CSMD2 NEDD9 POTEE SRGAP3 FARP1 CAPRIN2 CNTNAP2 POTEI	7.14e-06	313	162	12	GO:0099173
GeneOntologyBiologicalProcess	actin filament-based process	LIMA1 ABL2 MYO1D POTEF SPTB RDX PLEKHG2 NEDD9 FAM171A1 POTEE LATS1 NUP155 FARP1 TBCK IQSEC1 NOSTRIN POTEI ATP2A2 TNXB IQGAP3 CNN1	9.86e-06	912	162	21	GO:0030029
GeneOntologyBiologicalProcess	actin cytoskeleton organization	LIMA1 ABL2 MYO1D POTEF SPTB RDX PLEKHG2 NEDD9 FAM171A1 POTEE LATS1 FARP1 TBCK IQSEC1 NOSTRIN POTEI TNXB IQGAP3 CNN1	1.86e-05	803	162	19	GO:0030036
GeneOntologyBiologicalProcess	cell junction organization	ABL2 POTEF SPTB ROR2 DGKB RDX CSMD2 NEDD9 PARD6B POTEE PTPRJ ELFN1 SRGAP3 FARP1 CAPRIN2 CNTNAP2 IQSEC1 C1QA POTEI CDH12	8.13e-05	974	162	20	GO:0034330
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEF POTEE FARP1 POTEI	9.78e-05	31	162	4	GO:0098974
GeneOntologyBiologicalProcess	synapse organization	ABL2 POTEF SPTB ROR2 DGKB CSMD2 NEDD9 POTEE ELFN1 SRGAP3 FARP1 CAPRIN2 CNTNAP2 IQSEC1 C1QA POTEI	1.02e-04	685	162	16	GO:0050808
GeneOntologyCellularComponent	extrinsic component of postsynaptic membrane	DGKB FARP1 C1QA	6.78e-04	22	166	3	GO:0098890
GeneOntologyCellularComponent	actin cytoskeleton	LIMA1 ABL2 MYO1D POTEF SIPA1L3 SPTB TOPBP1 RDX GCK MSRA POTEE POTEI CNN1	7.13e-04	576	166	13	GO:0015629
GeneOntologyCellularComponent	extrinsic component of plasma membrane	DGKB FARP1 C1QA MCF2L ATP2A2 CDH12	7.99e-04	137	166	6	GO:0019897
GeneOntologyCellularComponent	host intracellular region	GBP7 GBP4	9.21e-04	6	166	2	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP7 GBP4	9.21e-04	6	166	2	GO:0030430
GeneOntologyCellularComponent	host cell part	GBP7 GBP4	9.21e-04	6	166	2	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP7 GBP4	9.21e-04	6	166	2	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP7 GBP4	9.21e-04	6	166	2	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP7 GBP4	9.21e-04	6	166	2	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP7 GBP4	9.21e-04	6	166	2	GO:0020005
Domain	GBP_C	GBP7 GBP4 ATL2	7.22e-05	10	161	3	PF02841
Domain	G_GB1_RHD3_dom	GBP7 GBP4 ATL2	9.86e-05	11	161	3	IPR030386
Domain	Guanylate-bd_N	GBP7 GBP4 ATL2	9.86e-05	11	161	3	IPR015894
Domain	Guanylate-bd_C	GBP7 GBP4 ATL2	9.86e-05	11	161	3	IPR003191
Domain	GBP	GBP7 GBP4 ATL2	9.86e-05	11	161	3	PF02263
Domain	G_GB1_RHD3	GBP7 GBP4 ATL2	9.86e-05	11	161	3	PS51715
Domain	Actin_CS	POTEF POTEE POTEI	3.24e-04	16	161	3	IPR004001
Domain	ACTINS_2	POTEF POTEE POTEI	3.91e-04	17	161	3	PS00432
Domain	aa-tRNA-synth_I_CS	CARS1 YARS1 QARS1	4.66e-04	18	161	3	IPR001412
Domain	Actin/actin-like_CS	POTEF POTEE POTEI	4.66e-04	18	161	3	IPR020902
Domain	Rossmann-like_a/b/a_fold	CARS1 PAPSS1 YARS1 QARS1	5.05e-04	43	161	4	IPR014729
Domain	-	CARS1 PAPSS1 YARS1 QARS1	5.05e-04	43	161	4	3.40.50.620
Domain	ACTINS_ACT_LIKE	POTEF POTEE POTEI	5.50e-04	19	161	3	PS01132
Domain	VWC_out	FRAS1 VWF MUC2	5.50e-04	19	161	3	SM00215
Domain	AA_TRNA_LIGASE_I	CARS1 YARS1 QARS1	5.50e-04	19	161	3	PS00178
Domain	Ank_2	ANKK1 GLS2 POTEF POTEG POTEE POTEM TNKS POTEI	5.64e-04	215	161	8	PF12796
Domain	Flavin_mOase	FMO3 FMO4	7.26e-04	5	161	2	IPR000960
Domain	DiMe-aniline_mOase	FMO3 FMO4	7.26e-04	5	161	2	IPR012143
Domain	FMO-like	FMO3 FMO4	7.26e-04	5	161	2	PF00743
Domain	Flavin_mOase-like	FMO3 FMO4	7.26e-04	5	161	2	IPR020946
Domain	RETICULON	RTN3 RTN1	7.26e-04	5	161	2	PS50845
Domain	Ank	ANKK1 GLS2 POTEF POTEG POTEE POTEM TNKS POTEI	8.27e-04	228	161	8	PF00023
Pathway	REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION	CARS1 YARS1 KARS1 QARS1	3.80e-05	24	114	4	M6591
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	LIMA1 DNAJC13 ABCF1 VWF MYO1D NRDC PRXL2B SIPA1L3 SPTB DGKB RTN3 RDX UPF1 RTN1 YARS1 KARS1 SF3B1 TTC7B SACS SRGAP3 FARP1 RPTOR PI4KA IQSEC1 C1QA SAMM50 ATP2A2 RPL3	2.20e-10	1431	166	28	37142655
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIMA1 DNAJC13 ABCF1 PATL1 THOC2 NSUN2 MIER1 GATAD2B MSH6 LATS1 SF3B1 BAZ2A RPTOR ASPH IQSEC1 OSBPL11 ATP2A2 PCDH7 WDR44	6.46e-09	774	166	19	15302935
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF POTEG POTEE POTEM POTEI	6.74e-09	15	166	5	16824795
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ABCF1 MYO1D NRDC CARS1 SMC4 RTN3 RDX UPF1 THOC2 TTC3 NSUN2 YARS1 MSH6 KARS1 SF3B1 NUP155 XPO5 RPTOR PI4KA SAMM50 ATL2 QARS1 ATP2A2 RPL3 IQGAP3	1.99e-08	1425	166	25	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KIF13B LIMA1 GLS2 MYO1D POTEF SIPA1L3 EML6 SMC4 RDX TTC3 PRX FER1L6 ACSL4 POTEE LATS1 SF3B1 SACS CAPRIN2 NOSTRIN POTEI MCF2L ATP2A2 DNAH8 CCDC191 RPL3	2.50e-08	1442	166	25	35575683
Pubmed	Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity.	VWF ST3GAL4 F8	1.07e-07	3	166	3	27584569
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAPKAP1 KIF13B LIMA1 ABL2 POTEF SIPA1L3 ROR2 PLEKHG2 PPM1A C6orf132 FAM171A1 LATS1 PIK3C3 RPTOR PI4KA IQSEC1 PCDH7	8.97e-07	861	166	17	36931259
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF13B LIMA1 DNAJC13 SIPA1L3 RDX UPF1 TTC3 RTN1 GATAD2B FAM171A1 SF3B1 SRGAP3 FARP1 RPTOR PI4KA NT5C2 IQSEC1 TNKS	9.21e-07	963	166	18	28671696
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	FRAS1 ABCF1 CLGN GPATCH1 ROR2 CARS1 RTN3 UPF1 MSH6 SF3B1 RPL3	2.10e-06	375	166	11	32788342
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DNAJC13 ABCF1 RASA3 ADNP2 SMC4 UPF1 NSUN2 ACSL4 MSH6 KARS1 SF3B1 NUP155 BAZ2A RPTOR PI4KA ASPH IQSEC1 SAMM50 QARS1 ATP2A2 RPL3	2.13e-06	1353	166	21	29467282
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	ABCF1 MYO1D SMC4 PATL1 UPF1 NSUN2 GATAD2B KARS1 SF3B1 ASPH QARS1 RPL3	2.94e-06	469	166	12	37314180
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ABCF1 MYO1D SMC4 UPF1 THOC2 NSUN2 MSH6 KARS1 SF3B1 NUP155 XPO5 BAZ2A ATP2A2 RPL3	3.39e-06	653	166	14	22586326
Pubmed	A class of dynamin-like GTPases involved in the generation of the tubular ER network.	RTN3 RTN1 ATL2	3.69e-06	7	166	3	19665976
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ABCF1 ACSS1 SMC4 RDX PATL1 UPF1 LXN THOC2 NSUN2 YARS1 MSH6 KARS1 SF3B1 XPO5 BAZ2A IQSEC1 QARS1 PCCA ATP2A2 RPL3	5.32e-06	1318	166	20	30463901
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DNAJC13 SMC4 MSH6 XPO5 PI4KA CNTNAP2 ATP2A2 IQGAP3	6.20e-06	202	166	8	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	DNAJC13 POTEF GPATCH1 SMC4 THOC2 SF3B1 ATP2A2 IQGAP3	6.20e-06	202	166	8	24639526
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEE POTEM POTEI	8.78e-06	9	166	3	16364570
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	ABCF1 RDX UPF1 NSUN2 YARS1 ACSL4 POTEE KARS1 SF3B1 NUP155 ASPH AGMAT ATP2A2 RPL3	8.89e-06	711	166	14	33022573
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	COL4A2 MAPKAP1 FRAS1 DNAJC13 ABCF1 ROR2 RTN3 UPF1 TTC3 FAM171A1 SF3B1 NUP155 SACS BAZ2A FARP1 PI4KA ASPH SAMM50 ATP2A2 RPL3 PCDH7	9.10e-06	1487	166	21	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SPTLC3 DNAJC13 RASA3 SIPA1L3 SPTB ROR2 RTN3 PATL1 TTC3 CASZ1 MSRA PTPRJ PIK3C3 FARP1 RPTOR TBCK ASPH NT5C2 SAMM50 MCF2L PCCA	9.29e-06	1489	166	21	28611215
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	MAPKAP1 ABCF1 GPATCH1 RDX UPF1 GATAD2B SF3B1 RPTOR	9.78e-06	215	166	8	35973513
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	LIMA1 ABCF1 GPATCH1 RDX UPF1 THOC2 NSUN2 RTN1 MSH6 KARS1 SF3B1 BAZ2A OSBPL11 PCCA RPL3 WDR44	1.14e-05	934	166	16	33916271
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CLGN SMC4 RTN3 UPF1 NSUN2 RTN1 KARS1 NUP155 XPO5 RPTOR PI4KA ASPH SAMM50 QARS1 ATP2A2 IQGAP3	1.26e-05	942	166	16	31073040
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MAPKAP1 LIMA1 DNAJC13 NRDC CARS1 SMC4 RTN3 RDX PAPSS1 YARS1 SF3B1 NUP155 XPO5 PIK3C3 ASPH NT5C2 QARS1 ATP2A2 RPL3	1.52e-05	1297	166	19	33545068
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DNAJC13 ABCF1 TOPBP1 UPF1 THOC2 NSUN2 MSH6 KARS1 NUP155 PIK3C3 ASPH QARS1 SPTY2D1 IQGAP3	1.84e-05	759	166	14	35915203
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	MAPKAP1 LIMA1 MYO1D SMC4 UPF1 NSUN2 ACSL4 ASPH RPL3	2.07e-05	312	166	9	37120454
Pubmed	Intracellular interaction of von Willebrand factor and factor VIII depends on cellular context: lessons from platelet-expressed factor VIII.	VWF F8	2.26e-05	2	166	2	15731176
Pubmed	The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase.	GBP7 GBP4	2.26e-05	2	166	2	21142871
Pubmed	A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.	VWF F8	2.26e-05	2	166	2	38320121
Pubmed	Rise of levels of von Willebrand factor and factor VIII with age: Role of genetic and acquired risk factors.	VWF F8	2.26e-05	2	166	2	33221577
Pubmed	Mechano-covalent protection of coagulation factor VIII by von Willebrand factor.	VWF F8	2.26e-05	2	166	2	36240294
Pubmed	Inflammation, hemostasis, and the risk of kidney function decline in the Atherosclerosis Risk in Communities (ARIC) Study.	VWF F8	2.26e-05	2	166	2	19110358
Pubmed	Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.	VWF F8	2.26e-05	2	166	2	23690449
Pubmed	Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.	VWF F8	2.26e-05	2	166	2	22219226
Pubmed	von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.	VWF F8	2.26e-05	2	166	2	26635035
Pubmed	The role of VWF in the immunogenicity of FVIII.	VWF F8	2.26e-05	2	166	2	18549909
Pubmed	The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor.	VWF F8	2.26e-05	2	166	2	9218428
Pubmed	The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor.	VWF F8	2.26e-05	2	166	2	7756647
Pubmed	Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort.	VWF F8	2.26e-05	2	166	2	18535282
Pubmed	Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus.	VWF F8	2.26e-05	2	166	2	20624989
Pubmed	Association of the factor VIII light chain with von Willebrand factor.	VWF F8	2.26e-05	2	166	2	3134349
Pubmed	The influence of von Willebrand factor on factor VIII activity measurements.	VWF F8	2.26e-05	2	166	2	18983499
Pubmed	Factor VIII and von Willebrand factor changes during normal pregnancy and puerperium.	VWF F8	2.26e-05	2	166	2	14517489
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	2.26e-05	2	166	2	19669888
Pubmed	Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities.	VWF F8	2.26e-05	2	166	2	15471879
Pubmed	The defective interaction between von Willebrand factor and factor VIII in a patient with type 1 von Willebrand disease is caused by substitution of Arg19 and His54 in mature von Willebrand factor.	VWF F8	2.26e-05	2	166	2	8562925
Pubmed	Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery.	VWF C1QA	2.26e-05	2	166	2	38155969
Pubmed	Characterization of junctate-SERCA2a interaction in murine cardiomyocyte.	ASPH ATP2A2	2.26e-05	2	166	2	19896466
Pubmed	von Willebrand factor variant p.Arg924Gln marks an allele associated with reduced von Willebrand factor and factor VIII levels.	VWF F8	2.26e-05	2	166	2	20492463
Pubmed	Solution structure of the major factor VIII binding region on von Willebrand factor.	VWF F8	2.26e-05	2	166	2	24700780
Pubmed	Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.	VWF F8	2.26e-05	2	166	2	21940821
Pubmed	Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings.	VWF F8	2.26e-05	2	166	2	26473492
Pubmed	Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment.	VWF F8	2.26e-05	2	166	2	20194895
Pubmed	VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.	VWF F8	2.26e-05	2	166	2	23349392
Pubmed	Interaction between VWF and FVIII in treating VWD.	VWF F8	2.26e-05	2	166	2	25605439
Pubmed	von Willebrand factor modulates immune complexes and the recall response against factor VIII in a murine hemophilia A model.	VWF F8	2.26e-05	2	166	2	37756521
Pubmed	Von Willebrand Factor Interacts with Surface-Bound C1q and Induces Platelet Rolling.	VWF C1QA	2.26e-05	2	166	2	27698012
Pubmed	Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.	VWF F8	2.26e-05	2	166	2	17958741
Pubmed	Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis.	GBP7 GBP4	2.26e-05	2	166	2	37621179
Pubmed	Von Willebrand factor processing.	VWF F8	2.26e-05	2	166	2	28139814
Pubmed	Von Willebrand and Factor VIII Portosystemic Circulation Gradient in Cirrhosis: Implications for Portal Vein Thrombosis.	VWF F8	2.26e-05	2	166	2	32032127
Pubmed	Anti-heavy-chain monoclonal antibodies directed to the acidic regions of the factor VIII molecule inhibit the binding of factor VIII to phospholipids and von Willebrand factor.	VWF F8	2.26e-05	2	166	2	12958606
Pubmed	Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.	VWF F8	2.26e-05	2	166	2	37720212
Pubmed	Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.	VWF F8	2.26e-05	2	166	2	23168412
Pubmed	Physiological Roles of the von Willebrand Factor-Factor VIII Interaction.	VWF F8	2.26e-05	2	166	2	32189311
Pubmed	Factor VIII binding affects the mechanical unraveling of the A2 domain of von Willebrand factor.	VWF F8	2.26e-05	2	166	2	32544272
Pubmed	Von Willebrand factor accelerates platelet adhesion and thrombus formation on a collagen surface in platelet-reduced blood under flow conditions.	VWF F8	2.26e-05	2	166	2	15459008
Pubmed	A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.	VWF F8	2.26e-05	2	166	2	23335368
Pubmed	High levels of coagulation factors and venous thrombosis risk: strongest association for factor VIII and von Willebrand factor.	VWF F8	2.26e-05	2	166	2	30471183
Pubmed	Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding.	VWF F8	2.26e-05	2	166	2	12719775
Pubmed	The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.	VWF F8	2.26e-05	2	166	2	30642920
Pubmed	Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.	VWF F8	2.26e-05	2	166	2	16823491
Pubmed	The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.	VWF F8	2.26e-05	2	166	2	30111575
Pubmed	Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells.	VWF F8	2.26e-05	2	166	2	35950488
Pubmed	Coagulation factor VIII regulates von Willebrand factor homeostasis invivo.	VWF F8	2.26e-05	2	166	2	37726033
Pubmed	A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.	VWF F8	2.26e-05	2	166	2	22855607
Pubmed	Sources of variation in factor VIII, von Willebrand factor and fibrinogen measurements: implications for detecting deficiencies and increased plasma levels.	VWF F8	2.26e-05	2	166	2	20627205
Pubmed	Evaluation of von Willebrand factor phenotypes and genotypes in Hemophilia A patients with and without identified F8 mutations.	VWF F8	2.26e-05	2	166	2	25780857
Pubmed	The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin.	VWF MUC2	2.26e-05	2	166	2	9407109
Pubmed	Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans.	VWF F8	2.26e-05	2	166	2	25779970
Pubmed	Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A.	VWF F8	2.26e-05	2	166	2	27749002
Pubmed	von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins.	VWF F8	2.26e-05	2	166	2	17119108
Pubmed	Correlation between von Willebrand factor antigen, von Willebrand factor ristocetin cofactor activity and factor VIII activity in plasma.	VWF F8	2.26e-05	2	166	2	17786534
Pubmed	Abnormal von Willebrand factor secretion, factor VIII stabilization and thrombus dynamics in type 2N von Willebrand disease mice.	VWF F8	2.26e-05	2	166	2	28581694
Pubmed	Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.	VWF F8	2.26e-05	2	166	2	27207787
Pubmed	High factor VIII antigen levels increase the risk of venous thrombosis but are not associated with polymorphisms in the von Willebrand factor and factor VIII gene.	VWF F8	2.26e-05	2	166	2	11722428
Pubmed	Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells.	VWF F8	2.26e-05	2	166	2	16953272
Pubmed	RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains.	RTN3 RTN1	2.26e-05	2	166	2	28733667
Pubmed	Type 2N von Willebrand disease due to compound heterozygosity for R854Q and a novel R763G mutation at the cleavage site of von Willebrand factor propeptide.	VWF F8	2.26e-05	2	166	2	16953269
Pubmed	Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.	VWF F8	2.26e-05	2	166	2	22559004
Pubmed	Factor VIII deficiency not induced by FVIII gene mutation in a female first cousin of two brothers with haemophilia A.	VWF F8	2.26e-05	2	166	2	12406074
Pubmed	A new method measuring the interaction between von Willebrand factor and coagulation factor VIII.	VWF F8	2.26e-05	2	166	2	21094987
Pubmed	Von Willebrand Factor and Factor VIII levels in Egyptian children with newly diagnosed acute lymphoblastic leukemia in relation to peripheral blast cells and steroid therapy.	VWF F8	2.26e-05	2	166	2	25105915
Pubmed	A von Willebrand factor fragment containing the D'D3 domains is sufficient to stabilize coagulation factor VIII in mice.	VWF F8	2.26e-05	2	166	2	24850761
Pubmed	Role of hemostatic factors on the risk of venous thrombosis in people with impaired kidney function.	VWF F8	2.26e-05	2	166	2	24211824
Pubmed	Recombinant and plasma-derived factor VIII products induce distinct splenic cytokine microenvironments in hemophilia A mice.	F8 MUC2	2.26e-05	2	166	2	19411636
Pubmed	The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.	VWF F8	2.26e-05	2	166	2	25955153
Pubmed	Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells.	GBP7 GBP4	2.26e-05	2	166	2	9659399
Pubmed	The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration.	PPM1A LATS1	2.26e-05	2	166	2	33630828
Pubmed	Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A.	VWF F8	2.26e-05	2	166	2	20606161
Interaction	RAC1 interactions	DOCK3 LIMA1 VWF ABL2 RASA3 SIPA1L3 ROR2 RDX PLEKHG2 YARS1 PARD6B FAM171A1 LATS1 NUP155 PTPRJ XPO5 SRGAP3 FARP1 PI4KA OSBPL11 C1QA MCF2L ATP2A2 RPL3 PCDH7 IQGAP3	5.40e-07	1063	165	26	int:RAC1
Interaction	RHOF interactions	MAPKAP1 MYO1D RASA3 SIPA1L3 ROR2 RDX NSUN2 YARS1 PARD6B FAM171A1 POTEE TTC7B NUP155 PTPRJ XPO5 FARP1 PI4KA ATP2A2 PCDH7 IQGAP3	6.69e-07	673	165	20	int:RHOF
Interaction	KCTD13 interactions	LIMA1 DNAJC13 ABCF1 VWF MYO1D NRDC PRXL2B SIPA1L3 SPTB DGKB RTN3 RDX UPF1 RTN1 YARS1 KARS1 SF3B1 TTC7B SACS SRGAP3 FARP1 RPTOR PI4KA IQSEC1 C1QA SAMM50 ATP2A2 RPL3	8.73e-06	1394	165	28	int:KCTD13
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEG POTEE POTEM POTEI	1.03e-08	13	112	5	685
GeneFamily	Ankyrin repeat domain containing	ANKK1 GLS2 POTEF POTEG POTEE POTEM TNKS POTEI	1.32e-04	242	112	8	403
GeneFamily	Aminoacyl tRNA synthetases, Class I	CARS1 YARS1 QARS1	2.09e-04	19	112	3	131
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASA3 SPTB PLEKHG2 FARP1 OSBPL11 MCF2L	1.79e-03	206	112	6	682
Coexpression	GSE27786_LSK_VS_BCELL_UP	MAPKAP1 LXN TTC3 PAPSS1 NSUN2 C6orf132 MSRA TNKS IQGAP3	5.52e-06	200	166	9	M4743
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Capillary\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL4A2 VWF RDX F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	4.38e-09	200	166	10	6c0498a5868891e8e22c03469d00669b20249b1a
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A2 VWF RDX F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	4.38e-09	200	166	10	7020045b933cb104fb99b79524cb0d4734b8636d
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL4A2 VWF RDX F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	4.38e-09	200	166	10	e9913511a129bb3cee85e7ebf565b951dab91542
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	DOCK3 CASZ1 POTEE TTC7B RPTOR DIO3 RPE65 CNN1 CDH12	1.25e-08	165	166	9	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF RDX CASZ1 PRX NEDD9 RXFP1 NOSTRIN MRAP2	5.28e-08	195	166	9	dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SIPA1L3 CASZ1 PARD6B FAM171A1 PTPRJ SRGAP3 FARP1 PCCA	5.28e-08	195	166	9	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ITGA11 MYO1D ROR2 RXFP1 PCDH7 TNXB ANO3 CNN1	5.52e-08	196	166	9	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ITGA11 MYO1D ROR2 RXFP1 PCDH7 TNXB ANO3 CNN1	5.52e-08	196	166	9	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF LXN PRX NEDD9 GBP4 RXFP1 NOSTRIN MRAP2	5.76e-08	197	166	9	9b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	6.02e-08	198	166	9	2400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF RDX F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN	6.02e-08	198	166	9	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF LXN PRX NEDD9 GBP4 RXFP1 NOSTRIN MRAP2	6.02e-08	198	166	9	75270600b5b29187dfa86f01f8f927ae0621cda4
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF F8 PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	6.28e-08	199	166	9	8db1acdcabf97f01b9ca17456c48ec8ac4928390
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B SPTLC3 DGKB CSMD3 RTN1 SACS ATL2 CDH12	2.03e-07	165	166	8	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B SPTLC3 DGKB CSMD3 RTN1 SACS ATL2 CDH12	3.63e-07	178	166	8	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B SPTLC3 DGKB CSMD3 RTN1 SACS ATL2 CDH12	3.95e-07	180	166	8	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	COL4A2 VWF CASZ1 PRX FAM171A1 GBP4 RXFP1 MCF2L	4.86e-07	185	166	8	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 KIF13B PLEKHG2 TTC3 F8 MSH6 CRYGN FARP1	5.07e-07	186	166	8	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 KIF13B PLEKHG2 TTC3 F8 MSH6 CRYGN FARP1	5.07e-07	186	166	8	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 KIF13B PLEKHG2 TTC3 F8 MSH6 CRYGN FARP1	5.07e-07	186	166	8	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	COL4A2 VWF RDX CASZ1 PRX RXFP1 NOSTRIN MCF2L	5.95e-07	190	166	8	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ROR2 EML6 ST3GAL4 CASZ1 FAM171A1 SRGAP3 PCDH7	6.44e-07	192	166	8	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ROR2 EML6 ST3GAL4 CASZ1 FAM171A1 SRGAP3 PCDH7	6.44e-07	192	166	8	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MYO1D VSIR NEDD9 FAM171A1 RXFP1 NOSTRIN MCF2L	6.70e-07	193	166	8	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)\|Adult / Lineage, Cell type, age group and donor	COL4A2 VWF PRX FAM171A1 GBP4 RXFP1 NOSTRIN MCF2L	6.70e-07	193	166	8	39c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 VWF F8 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	6.97e-07	194	166	8	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	367C-Endothelial_cells-Endothelial-E-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 VWF PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	7.24e-07	195	166	8	65fc50e3818e902028fc4226070fa57609c66b9c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ITGA11 FMO3 MYO1D ROR2 PCDH7 ANO3 CNN1	7.24e-07	195	166	8	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ITGA11 FMO3 MYO1D ROR2 PCDH7 ANO3 CNN1	7.24e-07	195	166	8	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF RDX F8 PRX GBP4 RXFP1 NOSTRIN	7.24e-07	195	166	8	a08a3261679f89bb63ca2589d79b6deff716ccad
ToppCell	367C-Endothelial_cells-Endothelial-E\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 VWF PRX NEDD9 GBP4 RXFP1 NOSTRIN MCF2L	7.24e-07	195	166	8	3b79e6bb525b17192ecec9e1227a29c419968144
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF RDX F8 PRX NEDD9 RXFP1 NOSTRIN MCF2L	7.53e-07	196	166	8	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	COL4A2 VWF RDX F8 FAM171A1 RXFP1 NOSTRIN MCF2L	7.82e-07	197	166	8	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 VWF F8 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	7.82e-07	197	166	8	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF RDX LXN PRX GBP4 RXFP1 NOSTRIN	7.82e-07	197	166	8	797ea1c9f75f88b51fdfc17a2b27ed0199ae64c9
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 VWF F8 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	8.12e-07	198	166	8	1d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF RDX LXN PRX NEDD9 RXFP1 NOSTRIN	8.12e-07	198	166	8	a75499f8f1630359b64717c300621aa3b1ab44d4
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 VWF RDX PRX NEDD9 GBP4 NOSTRIN MCF2L	8.44e-07	199	166	8	772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCell	distal-3-Endothelial-Capillary\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL4A2 VWF RDX F8 PRX GBP4 RXFP1 NOSTRIN	8.76e-07	200	166	8	bb792bfe34da99c400993155ffd8e0c15af29c26
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	COL4A2 VWF RDX LXN NEDD9 FAM171A1 NOSTRIN MCF2L	8.76e-07	200	166	8	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	distal-Endothelial-Capillary\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL4A2 VWF F8 PRX NEDD9 GBP4 NOSTRIN MCF2L	8.76e-07	200	166	8	0ee29b2bd9cd3a1c80e0535017814f752c3eb1fa
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL4A2 VWF RDX LXN NEDD9 FAM171A1 NOSTRIN MCF2L	8.76e-07	200	166	8	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL4A2 VWF RDX PRX NEDD9 FAM171A1 NOSTRIN MCF2L	8.76e-07	200	166	8	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	WDR64 DGKB CSMD2 CSMD3 CNTNAP2 DNAH8 CDH12	1.42e-06	148	166	7	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DGKB CSMD2 CSMD3 CNTNAP2 RXFP1 DNAH8 CDH12	2.28e-06	159	166	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ITGA11 ROR2 CCDC168 DPF3 RXFP1 MRAP2 ANO3	4.15e-06	174	166	7	df5664da3b93c233509781429a9c6d7edf1b8944
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 LXN CASZ1 GBP4 NOSTRIN MCF2L DNAH8	4.47e-06	176	166	7	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B SPTLC3 DGKB CSMD3 RTN1 ATL2 CDH12	4.47e-06	176	166	7	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 VWF RDX PRX NEDD9 GBP4 MCF2L	5.18e-06	180	166	7	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 VWF FAM171A1 GBP4 RXFP1 NOSTRIN TNXB	5.18e-06	180	166	7	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL4A2 VWF VSIR PRX GBP4 RXFP1 NOSTRIN	5.78e-06	183	166	7	3e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF LXN FAM171A1 RXFP1 NOSTRIN MCF2L MRAP2	5.78e-06	183	166	7	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF VSIR PRX GBP4 RXFP1 NOSTRIN MCF2L	6.42e-06	186	166	7	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF VSIR PRX GBP4 RXFP1 NOSTRIN MCF2L	6.42e-06	186	166	7	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A2 ITGA11 FMO3 RASA3 ROR2 RXFP1 ANO3	6.65e-06	187	166	7	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	COL4A2 VWF PRX TTC7B RXFP1 NOSTRIN MCF2L	6.65e-06	187	166	7	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ITGA11 FMO4 ABL2 DIO3 TNXB OSGIN1	6.85e-06	123	166	6	28be15b759c152662b29c323b1cc3f02f7830dbe
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 FMO3 ROR2 RXFP1 DNAH8 TNXB ANO3	7.13e-06	189	166	7	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG2 NEDD9 ACSL4 PTPRJ FARP1 RXFP1 ALPK2	7.13e-06	189	166	7	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF TDRD1 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	7.13e-06	189	166	7	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 FMO3 ROR2 RXFP1 DNAH8 TNXB ANO3	7.13e-06	189	166	7	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG2 NEDD9 ACSL4 PTPRJ FARP1 RXFP1 ALPK2	7.13e-06	189	166	7	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	COL4A2 VWF F8 PRX RXFP1 NOSTRIN MCF2L	7.38e-06	190	166	7	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 CASZ1 PRX GBP4 NOSTRIN MCF2L	7.38e-06	190	166	7	6847afca73e1b76c2e86187ccb1a164aefd8f17b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 CASZ1 PRX GBP4 NOSTRIN MCF2L	7.38e-06	190	166	7	2245f61ae0a720db21e29fcd4e910cf590d2655d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 COL4A2 EML6 NEDD9 SRGAP3 FARP1 DNAI4	7.64e-06	191	166	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	LIMA1 RTN3 PPIC APIP TTC7B OSBPL11 C1QA	7.64e-06	191	166	7	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 RDX CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	6115c20ffe414378508f3879e67815b6062341a7
ToppCell	PND07-Endothelial-Endothelial_blood-vessel\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 VWF GBP7 CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	12496bc964d1c572241410524a89ca1a9fdb7e34
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 VWF PRX FAM171A1 RXFP1 NOSTRIN MCF2L	8.46e-06	194	166	7	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	PND28-Endothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 RDX CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	b592c713204db7ae2f34a54f2d03d13834593c57
ToppCell	Adult-Endothelial\|Adult / Lineage, Cell type, age group and donor	COL4A2 VWF PRX FAM171A1 RXFP1 NOSTRIN MCF2L	8.46e-06	194	166	7	963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PPIC CASZ1 PRX NOSTRIN MCF2L DNAH8	8.46e-06	194	166	7	f6c9cc362ccdbc7e790f7c8d1c56cab3557c5306
ToppCell	PND28-Endothelial-Endothelial_blood-vessel\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 RDX CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	6317e9cdf96eb020f84d50bf41f803db5c9c04a0
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 GBP7 RTN1 CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	46e36817fd1ed27af8013375214c38c9a9271640
ToppCell	PND07-Endothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 VWF GBP7 CASZ1 PRX GBP4 NOSTRIN	8.46e-06	194	166	7	d1080c86884916c22894b27994141463f5919812
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF PRX FAM171A1 RXFP1 NOSTRIN MCF2L MRAP2	8.46e-06	194	166	7	fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	VWF LXN VSIR GBP4 RXFP1 NOSTRIN MRAP2	8.74e-06	195	166	7	c0ea25ed1a849e6efff885e98013a4f1d5134758
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 VWF F8 PRX FAM171A1 RXFP1 NOSTRIN	8.74e-06	195	166	7	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SIPA1L3 CASZ1 PARD6B PTPRJ SRGAP3 FARP1	9.04e-06	196	166	7	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 VWF RDX NEDD9 ELFN1 RXFP1 MCF2L	9.04e-06	196	166	7	c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SIPA1L3 CASZ1 PARD6B PTPRJ SRGAP3 FARP1	9.04e-06	196	166	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	3'-Distal_airway-Endothelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF PRX NEDD9 GBP4 NOSTRIN MCF2L	9.35e-06	197	166	7	9ffb823c0f3f23cc85f9fd3ca24f77817e90bd86
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF PRX NEDD9 GBP4 NOSTRIN MCF2L	9.35e-06	197	166	7	ca6bce1a92c6326f41a6300c31da02386bafa152
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF PRX NEDD9 GBP4 NOSTRIN MCF2L	9.35e-06	197	166	7	e3be7758a92f12e0a423394822957e1b7f995110
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	VWF VSIR PRX GBP4 RXFP1 NOSTRIN MRAP2	9.35e-06	197	166	7	21a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF PRX NEDD9 GBP4 NOSTRIN MCF2L	9.35e-06	197	166	7	6ac8d3e3f573e3848ab33e4df66dfaf8f948ea6c
ToppCell	tumor_Lung-Endothelial_cells-Tip-like_ECs\|tumor_Lung / Location, Cell class and cell subclass	COL4A2 VWF RDX PRX GBP4 RXFP1 NOSTRIN	9.35e-06	197	166	7	353b76ca3e2aa4b8f51396e7121c4baa114083a0
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A2 VWF PRX NEDD9 RXFP1 NOSTRIN MCF2L	9.35e-06	197	166	7	6a3c647af41fea923311562575a0d656fbc13cbe
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 VWF PRX NEDD9 GBP4 NOSTRIN MCF2L	9.66e-06	198	166	7	3aae7d146ebbb34da3239041a7c0334abff2597f
ToppCell	343B-Endothelial_cells\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 VWF F8 PRX FAM171A1 GBP4 NOSTRIN	9.66e-06	198	166	7	fab32347580c7a81ef1fe4fe7b325d9105a947d9
ToppCell	(6)_Endothelial-E\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL4A2 VWF F8 GBP4 RXFP1 NOSTRIN MCF2L	9.66e-06	198	166	7	a5e1b321376caf262ea48904d31afd1b8e9d3be2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 RTN3 TTC3 CSMD3 RTN1 MSRA CNTNAP2	9.66e-06	198	166	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 CSMD3 RTN1 MSRA CNTNAP2 PCDH7 CDH12	9.66e-06	198	166	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF PRX FAM171A1 GBP4 RXFP1 NOSTRIN MCF2L	9.66e-06	198	166	7	a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A2 VWF PRX NEDD9 GBP4 RXFP1 NOSTRIN	9.66e-06	198	166	7	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 VWF NEDD9 FAM171A1 SACS ELFN1 NOSTRIN	9.98e-06	199	166	7	d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCell	343B-Endothelial_cells-Endothelial-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 VWF PRX GBP4 RXFP1 NOSTRIN MCF2L	9.98e-06	199	166	7	bff61a784ef8bc040f5c7baabccaf7a7cddd5a31
ToppCell	Bronchial-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF F8 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	9.98e-06	199	166	7	36a230b80096455df26c2e2c8c05fd6b231508c5
ToppCell	Parenchymal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF F8 PRX FAM171A1 RXFP1 NOSTRIN MCF2L	9.98e-06	199	166	7	a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
Computational	Genes in the cancer module 133.	CARS1 YARS1 KARS1 QARS1	7.88e-06	15	97	4	MODULE_133
Computational	tRNA synthesis.	CARS1 YARS1 KARS1 QARS1	7.88e-06	15	97	4	MODULE_160
Computational	Genes in the cancer module 110.	CARS1 YARS1 KARS1 QARS1	1.04e-05	16	97	4	MODULE_110
Computational	Genes in the cancer module 35.	CARS1 YARS1 KARS1 QARS1	1.04e-05	16	97	4	MODULE_35
Disease	von Willebrand's disease 2 (is_marker_for)	VWF F8	2.85e-05	2	158	2	DOID:0060574 (is_marker_for)
Disease	hypertension	MYO1D EML6 ST3GAL4 CASZ1 MSRA PTPRJ RPTOR NT5C2 TNXB	4.40e-05	307	158	9	EFO_0000537
Disease	X-24309 measurement	DNAJC13 ACOT6 DPF3	1.61e-04	20	158	3	EFO_0800872
Disease	hereditary spastic paraplegia 12 (implicated_via_orthology)	RTN3 RTN1	1.70e-04	4	158	2	DOID:0110765 (implicated_via_orthology)
Disease	coronary artery disease	COL4A2 DNAJC13 GLS2 ST3GAL4 PPM1A EPG5 NEDD9 UBE2G1 PTPRJ CRYGN ELFN1 FARP1 RPTOR NT5C2 TNKS MCF2L TNXB	2.39e-04	1194	158	17	EFO_0001645
Disease	inflammatory bowel disease (implicated_via_orthology)	THEMIS PIK3C3 MUC2	3.18e-04	25	158	3	DOID:0050589 (implicated_via_orthology)
Disease	immunoglobulin superfamily containing leucine-rich repeat protein 2 measurement	ST3GAL4 LCN1P1	5.88e-04	7	158	2	EFO_0021879
Disease	Alcoholic Intoxication, Chronic	ANKK1 THEMIS VWF NRDC CARS1 CNTNAP2 CDH12	6.27e-04	268	158	7	C0001973
Disease	response to darapladib, cardiovascular event measurement	ACOT6 ANO3	7.81e-04	8	158	2	EFO_0006919, EFO_0008395
Disease	factor VIII measurement, venous thromboembolism	VWF ST3GAL4 PTPRJ	7.98e-04	34	158	3	EFO_0004286, EFO_0004630
Disease	Schizophrenia	ANKK1 ADNP2 ACOT6 CSMD2 MSRA PIK3C3 SRGAP3 PI4KA CNTNAP2 DIO3 PHOX2B ATP2A2 TNXB	9.73e-04	883	158	13	C0036341
Disease	venous thromboembolism, factor VII measurement	VWF PTPRJ MCF2L	1.11e-03	38	158	3	EFO_0004286, EFO_0004619
Disease	Autism Spectrum Disorders	NSUN2 CNTNAP2 DIO3 IQGAP3	1.14e-03	85	158	4	C1510586
Disease	factor VIII measurement	VWF ST3GAL4 RPL3	1.29e-03	40	158	3	EFO_0004630
Disease	venous thromboembolism, von Willebrand factor measurement	VWF ST3GAL4 PTPRJ	1.48e-03	42	158	3	EFO_0004286, EFO_0004629
Disease	oral microbiome measurement	FRAS1 NRDC CNTNAP2	1.48e-03	42	158	3	EFO_0801229
Disease	Paranoia	MANEA DNAH8	1.52e-03	11	158	2	C1456784
Disease	Paroxysmal atrial fibrillation	VWF BEST3 DGKB CASZ1 DPF3	1.56e-03	156	158	5	C0235480
Disease	familial atrial fibrillation	VWF BEST3 DGKB CASZ1 DPF3	1.56e-03	156	158	5	C3468561
Disease	Persistent atrial fibrillation	VWF BEST3 DGKB CASZ1 DPF3	1.56e-03	156	158	5	C2585653
Disease	hereditary spastic paraplegia (implicated_via_orthology)	RTN3 RTN1 ATL2	1.59e-03	43	158	3	DOID:2476 (implicated_via_orthology)
Disease	Atrial Fibrillation	VWF BEST3 DGKB CASZ1 DPF3	1.74e-03	160	158	5	C0004238
Disease	pneumonia	NEDD9 FAM171A1 MUC2	2.06e-03	47	158	3	EFO_0003106
Disease	depressive symptom measurement	ANKK1 VWF MSRA FARP1 NT5C2 TBC1D21 PCDH7 TNXB	2.17e-03	426	158	8	EFO_0007006
Disease	Alzheimer disease, dementia, family history of Alzheimer’s disease	ITGA11 EML6 MSRA	2.18e-03	48	158	3	EFO_0009268, MONDO_0001627, MONDO_0004975
Disease	lentiform nucleus measurement	FMO3 GATAD2B	2.49e-03	14	158	2	EFO_0004913
Disease	Replication Error Phenotype	MSH6 XPO5	2.86e-03	15	158	2	C1721098
Disease	Microsatellite Instability	MSH6 XPO5	2.86e-03	15	158	2	C0920269
Disease	Chronic Lymphocytic Leukemia	TOPBP1 SF3B1 CPEB1	3.22e-03	55	158	3	C0023434
Disease	focal segmental glomerulosclerosis	GPATCH1 CDH12	3.25e-03	16	158	2	EFO_0004236
Disease	Drug habituation	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0013170
Disease	Drug abuse	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0013146
Disease	Prescription Drug Abuse	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C4316881
Disease	Substance-Related Disorders	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0236969
Disease	Drug Use Disorders	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0013222
Disease	Drug Dependence	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C1510472
Disease	Substance Dependence	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0038580
Disease	Substance Use Disorders	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CSMD3 MSRA FARP1 DNAH8	3.45e-03	115	158	4	C0029231
Disease	platelet-to-lymphocyte ratio	VWF RASA3 MIER1 VSIR PTPRJ BAZ2A NOSTRIN	3.52e-03	363	158	7	EFO_0008446
Disease	Substance abuse problem	CSMD3 MSRA FARP1 DNAH8	3.56e-03	116	158	4	C0740858
Disease	facial morphology measurement	CCDC192 COL4A2 ITGA11 SIPA1L3 ROR2 CASZ1 FAM171A1 RPE65	3.74e-03	466	158	8	EFO_0007841
Disease	disease free survival	CCDC168 CNTNAP2	4.12e-03	18	158	2	EFO_0000409
Disease	uterine fibroid	ITGA11 THEMIS RTN3 CASZ1 PCDH7	4.45e-03	199	158	5	EFO_0000731
Disease	coagulation factor measurement	VWF MCF2L	5.08e-03	20	158	2	EFO_0004634

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKGTVTEFKHPGDFY	TDRD1	266	Q9BXT4
QFLDPTKGYAGHDLD	BEST3	256	Q8N1M1
KAINKAEYPEGFEIH	ACSL4	231	O60488
ELFQHLLGFKAKGDY	EPG5	586	Q9HCE0
GGESKADDPYAHLSK	ABCF1	241	Q8NE71
IGYPHDIKGEAAFAF	ACSS1	581	Q9NUB1
AAKHGFLAPGYKDAF	ELFN1	606	P0C7U0
AGYFHKAVKLNPDFS	PRMT9	121	Q6P2P2
TPKFGYKVHDEGHFA	CSMD2	1216	Q7Z408
FHLAQGDVLKIYDGK	CSMD3	1286	Q7Z407
PKKGHIYQGSEADSV	C1QA	221	P02745
AGKDLHVKYNCDIPG	NEDD9	271	Q14511
GDTYTAHAGAKFPIK	ABL2	436	P42684
AKGKDILYIGDHIFG	NT5C2	341	P49902
KYLAVSIPEDKHAGG	ALPK2	1021	Q86TB3
LENVKYLHLFKPGEG	CASZ1	341	Q86V15
LHSFGKVLGFDPAKD	BAZ2A	861	Q9UIF9
EAEGKTPLHVAAYFG	ANKK1	491	Q8NFD2
GVTFHPDQYKGEKGS	COL4A2	266	P08572
AIFYGGEPKAHSKAQ	ACOT6	381	Q3I5F7
NDGFAKVHYGFILKA	ASPH	486	Q12797
GAFGFQLKEVPAGKH	BPNT1	176	O95861
HIQPFKDEYEKFSGA	ATP10D	56	Q9P241
KDLKGFDPGEKYFHN	ADNP2	36	Q6IQ32
GRFVGHPGKYNKLFD	ANO3	661	Q9BYT9
KYGSQEHPIGDKSFQ	RASA3	806	Q14644
VGVDGSVYKLHPSFK	GCK	406	P35557
KENYQKVLSEHGFGP	MSRA	176	Q9UJ68
PEGVHQKGVKVYDDG	PALM2	161	Q8IXS6
KPGKFEEFYGLLQHV	PARD6B	36	Q9BYG5
GGYPEIVKENKLFEH	NSUN2	36	Q08J23
QAKYGDYNKEIHKPG	RDX	131	P35241
VACDEKGPKGYGFVH	PABPC1L2A	121	Q5JQF8
KGPKGYGFVHFQKQE	PABPC1L2A	126	Q5JQF8
YGADIESKNKHGLTP	POTEF	261	A5A3E0
VAKLEHAYKPVQFEG	PATL1	466	Q86TB9
KFSGFEASHGPIKAY	PTPRJ	836	Q12913
GTLGKDYHKSVEVFP	FAM171A1	451	Q5VUB5
FHSRDYKEPGVFNGK	FMO3	171	P31513
YEITTGPKHGFVENK	FRAS1	2481	Q86XX4
FKSKGNYDEGFGHRP	LIMA1	446	Q9UHB6
LKEQGYDPFKEDLNH	NUDT15	141	Q9NV35
LGKNGADEIKAHPFF	LATS1	996	O95835
HNPLKALGDQFYKEA	DPF3	6	Q92784
QKLDFFKQAHEGGPA	DIO3	121	P55073
FEGPEKVHSSYFEGK	IQSEC1	181	Q6DN90
DFTPKDNVHGLAYKG	GPATCH1	226	Q9BRR8
EPGKYTANRGKHVAY	LCN1P1	91	Q5VSP4
GYEAGKKDHEDFFTP	PCDH7	911	O60245
YKEFAVHLKRGPGQA	MUC2	71	Q02817
NFYPGVAEHKDISKL	DNAH8	971	Q96JB1
LHSQEYKIPEGFQGK	FMO4	171	P31512
ADKYLSGLVDKFPHL	PI4KA	986	P42356
FSVPGGHNLYLEEKK	GBP4	441	Q96PP9
FFVPGGHNIYLEAKK	GBP7	426	Q8N8V2
DYVHKFVGKEPSGLR	GLS2	236	Q9UI32
EKEDDKVFPGGSHTY	F8	141	P00451
LKEFPEELKNHGAYL	ITGA11	411	Q9UKX5
HELPTKQDGSGVKGY	GATAD2B	61	Q8WXI9
TKFLSDVYPDGFKGH	PCCA	501	P05165
YNHPFDGTFIREKGK	MSH6	111	P52701
KGGHFYSAKPEILRA	MSH6	161	P52701
YEGKHFTGQKLEVFG	CRYGN	11	Q8WXF5
PQIHDLYGKVKFTAE	IQGAP3	156	Q86VI3
EKHKYDILQSGFDGI	MANEA	306	Q5SRI9
AAEKKDPQGLGLHFY	NUP155	936	O75694
YGADIESKNKHGLTP	POTEE	261	Q6S8J3
ETGKDLYEPSHGAKV	PAPSS1	531	O43252
KGIGHVIKVPDNYGD	UPF1	386	Q92900
EAKHKAPGSADYGFA	C6orf132	1131	Q5T0Z8
GSTYAPIGEVHKDDK	ATP2A2	386	P16615
HIANGYKISGKEAPY	CR2	606	P20023
EAFFDKDYINKHPGD	DOCK3	1561	Q8IZD9
VEGDYFGLEFPDHKK	FARP1	76	Q9Y4F1
FFEAKEGHKLPVPGY	COX11	261	Q9Y6N1
PEANGHLKYDKFDDL	CCDC191	126	Q8NCU4
EHSYGLEGGKQFLEK	ATL2	251	Q8NHH9
FHGNGVLAKYNPEGK	DGKB	36	Q9Y6T7
KDGVKLPYFFHAGET	ADA2	346	Q9NZK5
HVQKDFKGGLNGAVY	CAPRIN2	231	Q6IMN6
GQGPHDESKIRKAYF	DNAJC13	1311	O75165
VPGKYTVVADHEKGG	MCF2L	1056	O15068
LAVGYGHFGFKEQKR	DNAI4	501	Q5VTH9
EPQYVGKLHSDLDKG	CDH12	71	P55289
GKIDQEIHKYNTPGF	CNTNAP2	1161	Q9UHC6
GVVYAGIDTDKHKYP	CPEB1	456	Q9BZB8
KAPEDSLKLQFIHGY	EML6	671	Q6ZMW3
LHQGKKGVDETYAFL	CCDC168	1746	Q8NDH2
EAVDHKEASGGPYEK	CCDC192	116	P0DO97
NYGEGPKAHIRKLAE	SAMM50	406	Q9Y512
DKVGKFGLGFNSVYH	SACS	1551	Q9NZJ4
QGFYEDIAHGKGKEL	SACS	1961	Q9NZJ4
TNHGKAPGIFKAEYH	CFAP47	166	Q6ZTR5
LGVQYHVFVDPAGAK	FPGT	81	O14772
FEQGLKAYGKDFHLI	MIER1	296	Q8N108
DYVVKKGLGHNFVSG	OSGIN1	181	Q9UJX0
PFYGGKLHRVTAEVK	OSBPL11	606	Q9BXB4
NGKKGHFPAAYVEEL	NOSTRIN	481	Q8IVI9
KNPYGFHLPKDDVKG	MMP20	251	O60882
FHLPKDDVKGIQALY	MMP20	256	O60882
KHGDEIYIAPSGVQK	APIP	51	Q96GX9
PGRGHKYHLKFAVEE	LXN	46	Q9BS40
DNKLDGPYFHPGKIQ	FER1L6	1486	Q2WGJ9
KGDARGQPKVFAYDH	KIF13B	46	Q9NQT8
DKVLLHFVQKSPGDY	PRXL2B	156	Q8TBF2
QAVQKSEEGHPFKAY	RTN3	901	O95197
QAVQKTDEGHPFKAY	RTN1	646	Q16799
GEALKFHKPGENYKT	QARS1	226	P47897
EHPAGGYKKLFETVE	RPE65	6	Q16518
SAPGEHVFVKGYEKG	YARS1	461	P54577
HVFVKGYEKGQPDEE	YARS1	466	P54577
HSYGKLVPEAVGDQK	CARS1	281	P49589
TFPDENFKLKHYGIG	PPIC	116	P45877
FLDPVFAEHLKGKGA	TBC1D21	216	Q8IYX1
GGAVAKPFITYHNEL	KARS1	276	Q15046
ALKGFHTDPEALKGF	LIAT1	301	Q6ZQX7
ALKGFHIDPEALKGF	LIAT1	311	Q6ZQX7
ALKGFHTDPEALKGF	LIAT1	341	Q6ZQX7
DKSINPLGGFVHYGE	RPL3	311	P39023
EDGGKYPVIFKHGDD	PIK3C3	626	Q8NEB9
KEHANYFGVDEKLGP	SIPA1L3	511	O60292
VHIAGFGYPDAYNKK	ST3GAL4	276	Q11206
PFNEYSKFDGKGHVG	MAPKAP1	156	Q9BPZ7
TDKALGEKLYHGAPF	AGMAT	191	Q9BSE5
YGADIESKNKHGLTP	POTEI	261	P0CG38
NGKPHFYDKLIVESF	SPTLC3	41	Q9NUV7
EDRFGKVYKGHLFGP	ROR2	481	Q01974
VKRIEFKHGGNYVPA	OSCP1	226	Q8WVF1
AKRTKDNFHGYNGIP	SPTY2D1	86	Q68D10
DNFHGYNGIPIEEKS	SPTY2D1	91	Q68D10
KDNGHKYFLSVLADP	RPTOR	511	Q8N122
GYIKPHVDSIKFCGA	ALKBH7	116	Q9BT30
GPDKCGEDYKLHFIF	CLGN	181	O14967
TKYGVKPHDIFEAND	CNN1	96	P51911
GGVADNHKDFKELRY	CNOT6L	426	Q96LI5
EGGFVEVIHDKKQYP	THEMIS	431	Q8N1K5
GAHGAQFPDAYGKEL	TMEM256	26	Q8N2U0
HILGFKFKFYQEPNG	THOC2	246	Q8NI27
HQGKEYAPGETVKIG	VWF	831	P04275
GPVSFEGLKAHKYSI	MRAP2	31	Q96G30
GSINYPDKKALSEGH	SRGAP3	921	O43295
ALGDFDYKCVHGKGP	PPM1A	196	P35813
SAKGVHLKGADEEPY	TNS4	516	Q8IZW8
FGYIAKAIGPHDVLA	SF3B1	1081	O75533
YQVAEGEGEAGHKLK	PRX	1291	Q9BXM0
FTPLHEAAAKGKYEI	TNKS	751	O95271
LLGPVDKGHDVTFYK	VSIR	56	Q9H7M9
YGFVGKKRHGPLVAE	TNXB	1131	P22105
FGVFYEGPETDHKQK	TMED6	136	Q8WW62
KAAHGFKGPYDFDQI	WDR44	486	Q5JSH3
ADGGGLVEKHYVFLK	XPO5	306	Q9HAV4
GHKLDSIEGKQLDYF	TTC3	946	P53804
EKPYGCNEHGKVFRV	ZNF534	196	Q76KX8
YPDENGFDAFLKKHG	NRDC	246	O43847
IGGFDLKFRGEYNKH	RXFP1	461	Q9HBX9
NFKSYAGEKILGPFH	SMC4	91	Q9NTJ3
KGGIHKYLEEFPDGF	TSTD2	381	Q5T7W7
GQVDKHYAGLKDVAE	SPTB	1666	P11277
GVEGAIHAKYDAIDK	TBCK	481	Q8TEA7
QKYLFEGKHEDAVPA	ZMYND12	96	Q9H0C1
YGEKPHTHKQRGKAF	ZNF563	136	Q8TA94
DAVAAKHPGLGEYAA	TMEM141	11	Q96I45
HAAEVYIGIGKPAEA	TTC7B	701	Q86TV6
AKPGFKHAGSEGELY	PLEKHG2	496	Q9H7P9
VHIGVKPFEYGKSFN	ZNF782	306	Q6ZMW2
EGGVFKAHLTFPKDY	UBE2G1	51	P62253
VPYKLFTDHGGLNEK	PHOX2B	81	Q99453
YGADIESKNKHGLTP	POTEG	261	Q6S5H5
YGADIESKNKHGLTP	POTEM	261	A6NI47
DPFSGVVFDHLKKLG	TOPBP1	61	Q92547
AGLFIHKEDAIGYDK	WDR64	41	B1ANS9
EKFPKVVYQGHEFGA	ZFP3	26	Q96NJ6
KSIFEGLKGHQEGYF	ZNF283	161	Q8N7M2
KYKGEFELHQGNAER	ZNF527	131	Q8NB42
DFKGDPIGGHINNYL	MYO1D	171	O94832