Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisordered domain specific binding

HSP90AB2P HSP90AA1

5.58e-0439182GO:0097718
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSP90AB2P HSP90AA1

5.87e-0440182GO:0140662
GeneOntologyMolecularFunctionprotein domain specific binding

SCNN1B GRID2 CXADR HSP90AB2P HSP90AA1

8.49e-04875185GO:0019904
GeneOntologyMolecularFunctionprotein folding chaperone

HSP90AB2P HSP90AA1

1.94e-0373182GO:0044183
GeneOntologyMolecularFunctionscaffold protein binding

GRID2 HSP90AA1

3.13e-0393182GO:0097110
GeneOntologyMolecularFunctionPDZ domain binding

GRID2 CXADR

5.40e-03123182GO:0030165
GeneOntologyMolecularFunctionunfolded protein binding

HSP90AB2P HSP90AA1

5.66e-03126182GO:0051082
GeneOntologyMolecularFunctionATP hydrolysis activity

FIGN HSP90AB2P HSP90AA1

6.82e-03441183GO:0016887
GeneOntologyMolecularFunctionintegrin binding

CXADR COMP

1.07e-02175182GO:0005178
GeneOntologyCellularComponentgamma-delta T cell receptor complex

TRGC1 TRGC2

1.05e-056182GO:0042106
GeneOntologyCellularComponentgrowth cone

EXOC3 CXADR HSP90AA1

1.14e-03245183GO:0030426
GeneOntologyCellularComponentsite of polarized growth

EXOC3 CXADR HSP90AA1

1.25e-03253183GO:0030427
MousePhenoabnormal pelvic girdle bone morphology

FIGN SCNN1B ORC3 COMP

1.34e-0687144MP:0004509
MousePhenoabnormal pelvic girdle joint morphology

FIGN COMP

3.34e-059142MP:0030819
MousePhenoabnormal hip joint morphology

FIGN COMP

3.34e-059142MP:0030829
MousePhenoabnormal girdle joint morphology

FIGN COMP

8.42e-0514142MP:0030818
MousePhenoabnormal head movements

FIGN GRID2 SERPINB12

1.33e-04103143MP:0000436
MousePhenoabnormal hindlimb joint morphology

FIGN COMP

1.75e-0420142MP:0030808
MousePhenoabnormal limb joint morphology

FIGN COMP

2.76e-0425142MP:0030805
MousePhenoabnormal stationary movement

FIGN GRID2 SERPINB12

3.81e-04147143MP:0001388
MousePhenodecreased circulating sodium level

SCNN1B TXNIP

5.75e-0436142MP:0005634
MousePhenostereotypic behavior

FIGN GRID2 SERPINB12

1.14e-03214143MP:0001408
Pubmed

Structure, organization, and somatic rearrangement of T cell gamma genes.

TRGC1 TRGC2

2.83e-0721923917858
Pubmed

Allelic differences in TCR gamma-chains alter gamma delta T cell antigen reactivity.

TRGC1 TRGC2

2.83e-0721928046225
Pubmed

Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness.

TRGC1 TRGC2

2.83e-0721921973682
Pubmed

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

TRGC1 TRGC2

2.83e-0721923486244
Pubmed

Physical linkage of mouse Tcrg-V genes. II. Regulatory features of the Vg4-Vg3 intergenic region.

TRGC1 TRGC2

2.83e-0721928119740
Pubmed

Organization of the murine T-cell receptor gamma locus.

TRGC1 TRGC2

2.83e-0721928244371
Pubmed

The genomic arrangement of T cell receptor variable genes is a determinant of the developmental rearrangement pattern.

TRGC1 TRGC2

2.83e-07219214691262
Pubmed

New T-cell receptor gamma haplotypes in wild mice and evidence for limited Tcrg-V gene polymorphism.

TRGC1 TRGC2

2.83e-0721928420824
Pubmed

Developmentally ordered V-J recombination in mouse T cell receptor gamma locus is not perturbed by targeted deletion of the Vgamma4 gene.

TRGC1 TRGC2

2.83e-0721929126983
Pubmed

Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes.

TRGC1 TRGC2

2.83e-0721928550103
Pubmed

Limited diversity of the rearranged T-cell gamma gene.

TRGC1 TRGC2

2.83e-0721923871915
Pubmed

Mapping genomic organization by field inversion and two-dimensional gel electrophoresis: application to the murine T-cell receptor gamma gene family.

TRGC1 TRGC2

2.83e-0721923375073
Pubmed

Langerhans cells are not required for epidermal Vgamma3 T cell homeostasis and function.

TRGC1 TRGC2

8.48e-07319221486908
Pubmed

Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma.

TRGC1 TRGC2

8.48e-0731922879283
Pubmed

Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.

TRGC1 TRGC2

2.82e-06519215821084
Pubmed

T cell receptor signaling for γδT cell development.

TRGC1 TRGC2

4.24e-06619230976362
Pubmed

Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.

HSP90AB2P HSP90AA1

5.93e-06719216288044
Pubmed

Stoichiometry of the murine gammadelta T cell receptor.

TRGC1 TRGC2

5.93e-06719216418397
Pubmed

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk.

TRGC1 TRGC2

5.93e-0671927477352
Pubmed

STAT5 is required for thymopoiesis in a development stage-specific manner.

TRGC1 TRGC2

2.20e-051319215294943
Pubmed

HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3.

HSP90AB2P HSP90AA1

2.56e-051419228739485
Pubmed

PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.

SERPINB12 HSP90AA1

2.56e-051419229178343
Pubmed

The HSP90 family of genes in the human genome: insights into their divergence and evolution.

HSP90AB2P HSP90AA1

3.38e-051619216269234
Pubmed

The human T-cell receptor gamma (TRG) genes.

TRGC1 TRGC2

6.49e-05221922527426
Pubmed

Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.

TXNIP HSP90AA1

1.76e-043619231669268
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

SERPINB12 CXADR HSP90AA1

4.05e-0426919330442662
Cytoband7p14

TRGC1 TRGC2

7.01e-05301927p14
CytobandEnsembl 112 genes in cytogenetic band chr14q32

HSP90AA1 IGHV1-2 ATG2B

1.56e-03566193chr14q32
CytobandEnsembl 112 genes in cytogenetic band chr7p14

TRGC1 TRGC2

2.34e-03174192chr7p14
Cytoband14q32.33

HSP90AA1 IGHV1-2

3.97e-0322819214q32.33
GeneFamilyT cell receptor gamma locus at 7p14

TRGC1 TRGC2

1.68e-0422162375
CoexpressionAIZARANI_LIVER_C12_NK_NKT_CELLS_4

TXNIP TRGC1 HSP90AA1

4.91e-0649183M39116
CoexpressionROPERO_HDAC2_TARGETS

TXNIP TRGC2 COMP

5.91e-05112183M8759
ToppCelltumor_Lung-T/NK_cells-Naive_CD8+_T|tumor_Lung / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2 HSP90AA1

6.32e-07164194a669d3b39dcd219a1973e266765e2f2b114438ef
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

TXNIP CYP1A1 TRGC1 TRGC2

7.13e-071691946d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|367C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2 HSP90AA1

1.04e-06186194d4be02813d590aa7ffe0d1553a27d257b9ab77fe
ToppCell(0)_T_CD8|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TXNIP ORC3 TRGC1 TRGC2

1.16e-0619119459b87beec2b12ad0a35d86f911423e3a0a3f4701
ToppCell367C-Lymphocytic|367C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2 HSP90AA1

1.21e-06193194b069a1cba2e1bf1c0d7479b11185fb416f18b14b
ToppCell(0)_NK/T_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TXNIP ORC3 TRGC1 TRGC2

1.29e-06196194baee29014dc56c71a6ef790bb7ecd5b5271cfcb0
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm_gut_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TXNIP TRGC1 TRGC2 HSP90AA1

1.29e-06196194528622874692d7d65c905738b078ab53acef5846
ToppCellCOVID_non-vent-Lymphocytic-T_cell-Gamma_Delta_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FIGN TRGC1 TRGC2

1.27e-0510819304bfb90634b691020f246a8afbebd3bf944d1e0e
ToppCelltumor_Lung-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TXNIP TRGC2 HSP90AA1

2.81e-05141193f62d78b3f998f3ea493647c4c5b86cfec2243f0b
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

TRGC1 TRGC2 HSP90AA1

2.87e-05142193eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 TRGC1 TRGC2

3.19e-05147193743767abdb3b5ecad870b617f515b037ce280818
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 TRGC1 TRGC2

3.25e-05148193e7bbb5ddf44b11b8495e83863fbf1fd9f3f24472
ToppCellMS-CD8-CD8_2|MS / Condition, Cell_class and T cell subcluster

TXNIP TRGC1 TRGC2

3.38e-0515019301c20d787ce269db0d153e63a600a8d9ead61856
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 TRGC1 TRGC2

3.80e-05156193c11ca6b1b5029c15aab91273cece70a487287839
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2

4.10e-05160193f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

CYP1A1 TRGC1 TRGC2

4.18e-05161193b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellMild-MAIT|World / Disease group and Cell class

TRGC1 TRGC2 IGHV1-2

4.41e-0516419321dc02997dfae73cf70ce291661928526605dba1
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRGC1 TRGC2 HSP90AA1

4.66e-05167193c2a0fdb35ec48b956be0686534b29164db6638ab
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

4.83e-05169193f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCellInfluenza_Severe-gd_T|Influenza_Severe / Disease group and Cell class

CYP1A1 TRGC1 TRGC2

4.91e-0517019359009c5a504ea8c6b4f6697299db219fd5edf7d6
ToppCellURO-Lymphocyte-T_NK-gdT|URO / Disease, Lineage and Cell Type

TXNIP TRGC1 TRGC2

5.09e-0517219397b1eb95234639fcaa5ea3c4ba7ec2f4eb929dbf
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCNN1B SERPINB12 HSP90AB2P

5.09e-0517219320ea9db009370aa6235365ce93e153eb5b28db94
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-MAIT|Multiple_Sclerosis / Disease, Lineage and Cell Type

TRGC1 TRGC2 HSP90AA1

5.09e-0517219318bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2

5.17e-05173193b06d6e7acb7086bb99600b680cf404c0ef06b52c
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRGC1 TRGC2 COMP

5.45e-05176193dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TXNIP TRGC1 TRGC2

5.45e-05176193ce85a13e10cf37f5cf38ca8b0bac6701b6d00ffd
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TXNIP TRGC1 TRGC2

5.54e-05177193d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

TXNIP TRGC1 TRGC2

5.54e-0517719334e9455790bae905dd91923792f4109d18b7686e
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TXNIP TRGC1 TRGC2

5.54e-05177193f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TXNIP TRGC1 TRGC2

5.54e-05177193936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TXNIP TRGC1 TRGC2

5.54e-05177193d5aeda113afaa2425874394610344570c9078478
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

TXNIP TRGC1 TRGC2

5.54e-051771936978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellIIF-Lymphocyte-T_NK-MAIT|IIF / Disease, Lineage and Cell Type

TRGC1 TRGC2 HSP90AA1

5.63e-05178193be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCellIIF-Lymphocyte-T_NK-gdT|IIF / Disease, Lineage and Cell Type

FIGN TRGC1 TRGC2

5.63e-051781933344d1328fd9c570c3a4b2629edec627a442d0e0
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

TXNIP TRGC1 TRGC2

5.82e-05180193857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRGC1 TRGC2 HSP90AA1

6.02e-051821938b8fd33e539e7e253c022481100223b17b279a73
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2

6.02e-0518219352baef8173df0a55307c375674a37c2488066738
ToppCellsevere_influenza-gd_T|severe_influenza / disease group, cell group and cell class (v2)

CYP1A1 TRGC1 TRGC2

6.02e-05182193b6b44c90af3f0c0dddb2b171087865d8c15a3973
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRGC1 TRGC2 HSP90AA1

6.11e-05183193983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TXNIP TRGC1 TRGC2

6.21e-05184193cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell|356C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC1 TRGC2

6.21e-051841935b4f18b26d03e8e5798cac70d124534749fc4cc0
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

TXNIP TRGC1 TRGC2

6.21e-05184193791f1bcb954aadc63d4117c400537d036f68734d
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN1_thymic_pro-T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRGC1 TRGC2 HSP90AA1

6.31e-051851935db31631a4b4c4bfeb28f02d8dab00a48d77bcba
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

6.42e-0518619371e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellControl-Lymphoid-CD8_T_cells|Lymphoid / Condition, Lineage and Cell class

TXNIP TRGC1 TRGC2

6.42e-05186193a8a4c0f4058f5bbc435dd2dd41d55383173a1358
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCNN1B CXADR HSP90AA1

6.52e-05187193b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCellILEUM-inflamed-(1)_CD8_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TXNIP TRGC1 TRGC2

6.52e-05187193a77d7ae44f47410bd92fb3aa0f44dce891752b63
ToppCellmetastatic_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

6.52e-051871937375f70a970a5d5a58b7c33ada2dcf6dcef525c6
ToppCellkidney_cells-Hypertensive_with+without-CKD|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

SCNN1B TXNIP CXADR

6.62e-0518819390188b60ff893754f7938fe8edab79758827168e
ToppCell(1)_T_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TXNIP ORC3 TRGC2

6.73e-05189193fa6b85676b2b61483ae27720d0715dbfcbcfbdf9
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TXNIP TRGC1 TRGC2

6.73e-051891932c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Trm/em_CD8|bone_marrow / Manually curated celltypes from each tissue

TXNIP TRGC2 HSP90AA1

6.73e-0518919317733be6ead1d24149d478023f731d23876b4f54
ToppCell(1)_T_cells-(1)_T_CD8_gd|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TRGC1 TRGC2 HSP90AA1

6.83e-05190193268772d2adff34f7175b8474e95b67fd96dc1234
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|367C / Donor, Lineage, Cell class and subclass (all cells)

TRGC1 TRGC2 HSP90AA1

6.83e-051901934240d52a465bc3f8016834b22a35c44ba2b0a9f4
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8|bone_marrow / Manually curated celltypes from each tissue

TXNIP TRGC2 HSP90AA1

6.83e-05190193be281c7c717c11ef3c5cbccd22628acf1bd9727f
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

GRID2 TRGC1 TRGC2

6.83e-05190193e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8|bone_marrow / Manually curated celltypes from each tissue

TXNIP TRGC2 HSP90AA1

6.94e-05191193db7b8f8826bf19d6eeee14319570a9e6e99ab2cb
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1B TXNIP HSP90AA1

6.94e-05191193fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TXNIP TRGC1 TRGC2

6.94e-05191193c4a2a8a7b864df282546e6ac53fcb2269cbb3345
ToppCellBLOOD--(1)_gd_T_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ORC3 TRGC1 TRGC2

6.94e-0519119347ced00ed6fb47ddc6e9baa76186ea974720defd
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|367C / Donor, Lineage, Cell class and subclass (all cells)

TRGC1 TRGC2 HSP90AA1

7.05e-05192193a0bd4a0d00246af4f6645e66a0dedfe36882cc60
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1B TXNIP HSP90AA1

7.05e-051921934510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1B TXNIP HSP90AA1

7.05e-051921930dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCellILEUM-non-inflamed-(1)_CD8_Trm|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TXNIP TRGC1 TRGC2

7.05e-05192193a9f89043c97cd2b0ba165e69ee5681094410af37
ToppCellnormal_Pleural_Fluid-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

7.16e-0519319375a0b3aa40bdb844dc48c2b6ad945c73e47b60d4
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TXNIP TRGC1 TRGC2

7.16e-05193193544de0988510cc57744710d7cafe07aa27a0b99d
ToppCellnormal_Pleural_Fluid-T/NK_cells-Naive_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

7.16e-05193193828f11c9081df74faf3b788456991e1a0cf99900
ToppCellCOVID-19_Severe-CD8+_T_activated|World / disease group, cell group and cell class

TXNIP TRGC2 HSP90AA1

7.16e-05193193ddc1db516568e03be8e82b2ca770c67756418185
ToppCellInfluenza_Severe-CD8+_Tem|World / Disease group and Cell class

TXNIP TRGC1 TRGC2

7.16e-05193193fce6138712353fba14eb046e10d54e112372658e
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

7.16e-05193193db9378c5bb5c27b321957a05dcabf40e97a3b725
ToppCellControl-Lymphocyte-T_NK|Control / Disease, Lineage and Cell Type

TXNIP TRGC1 TRGC2

7.16e-05193193eb8b8f6e52fd140fbacf3d6776458c6fc355e120
ToppCellfacs-Skin-Telogen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNIP ITPKC HSP90AA1

7.27e-05194193ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TXNIP TRGC1 TRGC2

7.27e-05194193bf2480acec5612cd8a3c33d3e7a98176dc6c9091
ToppCellmetastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T|metastatic_Lymph_Node / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

7.27e-0519419373c057b623829de793616d9d373a0018071d51d8
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNIP ITPKC HSP90AA1

7.27e-051941934d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD8_low_T|metastatic_Lymph_Node / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

7.27e-05194193b0595b98332fee7936e455240bbefe72b79c98b8
ToppCellURO-Lymphocyte-T_NK|URO / Disease, Lineage and Cell Type

TXNIP TRGC1 TRGC2

7.27e-051941934806c07dcf1bc6d9591548382b77817568eb16b6
ToppCellBLOOD--(1)_MAIT-like_CD8_T_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ORC3 TRGC1 TRGC2

7.27e-051941930064bcd9ac2fecec81f8d4e7d9f86f0089872fe7
ToppCellILEUM-non-inflamed-(1)_T_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TXNIP ORC3 TRGC2

7.27e-05194193d548e5cdf669776e840cc3129969897abfffc211
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRGC1 TRGC2 HSP90AA1

7.27e-05194193b571f5f021619df0eedda5dd6739673f41dfab61
ToppCellfacs-Skin-Telogen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNIP ITPKC HSP90AA1

7.27e-05194193bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1B TXNIP HSP90AA1

7.27e-0519419392b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRGC1 TRGC2 HSP90AA1

7.27e-05194193a8dc3336aa4ef497f6d26cede02ddac425e7c655
ToppCellBLOOD--(1)_EM_CTLs| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ORC3 TRGC1 TRGC2

7.27e-0519419366583c6cff3814902d6babdea3a2ae962decde65
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|tumor_Lung / Location, Cell class and cell subclass

TRGC1 TRGC2 HSP90AA1

7.27e-0519419321d789585b3085aeeae3bef595c6cc5ea1c3dc4f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

7.38e-05195193662b50a2aa97373bf343b88caace9717049c722a
ToppCell(1)_T_CD8_CTL|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ORC3 TRGC1 TRGC2

7.38e-05195193f582b854e5a4c52764aad5abe4e28ea77a7445f7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

7.38e-051951939b7157b5e4b81bc35b0e6d9b954279160ea57324
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|368C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC2 HSP90AA1

7.38e-05195193974bb20df9756d322f8b7de92db262e26d629bfa
ToppCellnormal_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TXNIP TRGC2 HSP90AA1

7.38e-051951933af8ea15e2ac8efdeb4d4f69357b83b8dbcfab8d
ToppCell368C-Lymphocytic-CD4_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP TRGC2 HSP90AA1

7.38e-05195193acb3bb9a38c4c58547cccaf2c2aff14aef56c679
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

TXNIP TRGC1 TRGC2

7.38e-051951939990440bda7fac5d00ef80444fab07459be625e1
ToppCell(1)_T_CD8_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ORC3 TRGC1 TRGC2

7.38e-051951932253590339b87692d350f9ea3d2aa851179967e1
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TXNIP TRGC1 TRGC2

7.49e-051961933f5bf202c5d8c15072255c133793c8ee6e8d932f
ToppCelllymphoid-T_cell-unlabelled(multiplets)|World / Lineage, cell class and subclass

TRGC1 TRGC2 HSP90AA1

7.49e-0519619378b006922307c154622d71fcbc79ae5eed3f4b23
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Cytotoxic_CD8+_T|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TXNIP TRGC1 TRGC2

7.49e-051961936789c88a99cadfd8122ece4b736ba6783ae6e6f5
ToppCellInfluenza_Severe-CD8+_Tem|Influenza_Severe / Disease group and Cell class

TXNIP TRGC1 TRGC2

7.49e-05196193c2d31b2a560309264e846271430a846f09a73ef8
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP TRGC1 TRGC2

7.49e-0519619337065ac2c89a8b5ed52af9f796e0c97909ee51a4
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TXNIP TRGC1 TRGC2

7.49e-051961930f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCellsevere-CD8+_Tem|World / disease stage, cell group and cell class

TXNIP TRGC1 TRGC2

7.49e-05196193b8156d31312660fe9c071cb10d7ef22af672c6c8
Drug1,2,4,7,8-pentachlorodibenzo-p-dioxin

CYP1A1 HSP90AA1

1.24e-057182CID000042836
Drug9-phenanthrol

CYP1A1 HSP90AA1

1.65e-058182CID000010229
Drug1,2-bis(2,4,6-tribromophenoxy)ethane

TXNIP CYP1A1

2.65e-0510182ctd:C081014
Druggedunin

TXNIP CYP1A1 HSP90AA1

3.80e-0584183ctd:C106014
Drugsteroid D

CXADR HSP90AA1

4.58e-0513182CID000454475
DrugCMV423

CYP1A1 HSP90AA1

4.58e-0513182CID000489128
Drugisopimpinellin

CYP1A1 CXADR

6.16e-0515182CID000068079
Drugracemethorphan

SCNN1B CYP1A1 GRID2

7.82e-05107183CID000003008
DrugDCDD

CYP1A1 HSP90AA1

1.00e-0419182CID000036613
Drugnobiletin

TXNIP CYP1A1

1.48e-0423182ctd:C008661
Drugtripterine

TXNIP CYP1A1 HSP90AA1

1.70e-04139183ctd:C050414
Drugcoumarin

CYP1A1 HSP90AA1 COMP

1.70e-04139183CID000000323
DrugPeCDD

CYP1A1 HSP90AA1

2.05e-0427182CID000038439
Drugimperatorin

CYP1A1 CXADR

2.37e-0429182CID000010212
Drugphenethyl isothiocyanate

TXNIP CYP1A1 SERPINB12 HSP90AA1

2.38e-04401184ctd:C058305
Drugmonamine

CXADR COMP

3.07e-0433182CID000004034
DrugHelveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A

SCNN1B TXNIP CYP1A1

3.07e-041701833945_UP
Drugperfluorobutyric acid

TXNIP CYP1A1

3.26e-0434182ctd:C033094
Drugwortmannin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

TXNIP CYP1A1 ATG2B

3.35e-04175183869_UP
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

TXNIP CYP1A1 ATG2B

3.63e-041801831065_UP
DrugHumic Substances

CYP1A1 HSP90AA1

3.66e-0436182ctd:D006812
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

TXNIP ITPKC ATG2B

3.81e-041831831074_UP
DrugAC1L3O4Q

CYP1A1 CXADR

3.87e-0437182CID000119057
Drug17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

TXNIP ITPKC HSP90AA1

3.87e-041841831051_UP
Drugperfluorohexanoic acid

TXNIP CYP1A1

4.08e-0438182ctd:C479228
DrugIndoles

CYP1A1 HSP90AA1

4.30e-0439182ctd:D007211
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; HL60; HG-U133A

TXNIP ITPKC ASB8

4.46e-041931831417_DN
DrugSulpiride

CYP1A1 HSP90AA1

4.52e-0440182ctd:D013469
Drugdiclofenac sodium; Up 200; 10uM; MCF7; HG-U133A

SCNN1B CYP1A1 EXOC3

4.80e-04198183333_UP
Drug16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione

FIGN CYP1A1

5.73e-0445182ctd:C020175
DrugAlbendazole

CYP1A1 HSP90AA1

5.99e-0446182ctd:D015766
Drugenniatins

CYP1A1 CXADR

6.52e-0448182ctd:C100264
Drugfelbamate

CYP1A1 HSP90AA1

6.52e-0448182ctd:C047360
Drug19-HETE

CYP1A1 HSP90AA1

6.79e-0449182CID006439528
DiseaseContact hypersensitivity

CYP1A1 HSP90AA1

9.51e-0471192C0162351
DiseaseContact Dermatitis

CYP1A1 HSP90AA1

9.51e-0471192C0011616
Diseasecoffee consumption measurement

CYP1A1 GRID2

6.04e-03182192EFO_0006781
DiseaseHypertensive disease

SCNN1B CYP1A1

6.56e-03190192C0020538

Protein segments in the cluster

PeptideGeneStartEntry
SSSFYVVMWKQMEQT

COMP

606

P49747
YWSSFMTSSMQLAKE

ATG2B

116

Q96BY7
TVTTAISWSLMYLVM

CYP1A1

321

P04798
RYMQWRETMSSTSTL

ITPKC

536

Q96DU7
MSSSMWYIMQSIQSK

ASB8

1

Q9H765
MISSTSVYGLKMQWT

FIGN

1

Q5HY92
TSTYSWTANMEQIMK

HSP90AB2P

366

Q58FF8
QMGSMTSTTLYNSMW

GRID2

596

O43424
WVTMTRDTSISTAYM

IGHV1-2

86

P23083
YDPKTDMWTAVASMS

KLHL5

681

Q96PQ7
SQKMPTSWLAEMTSS

CXADR

181

P78310
TSTYGWTANMERIMK

HSP90AA1

601

P07900
TWVLNTYTSTEMMRN

EXOC3

341

O60645
TQYKMTISMADWPSE

SCNN1B

451

P51168
KTHYSMDSLSSWYMT

ORC3

176

Q9UBD5
MDSLSSWYMTVTQKT

ORC3

181

Q9UBD5
NTMKTNDTYMKFSWL

TRGC1

61

P0CF51
NTMKTNDTYMKFSWL

TRGC2

61

P03986
ITYEKMVAWSSSENM

SERPINB12

276

Q96P63
TSSMASRTSSEMSWV

TXNIP

306

Q9H3M7