Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF823 ZNF274 ZNF473 ZNF174 PEG3 NSD1 ZNF213 ZNF226 REST CREBBP ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 PREB ZNF708 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF66 NFXL1 ZNF737 NLRC5 ZNF30 ZNF705B MGA PRDM14 EP300	8.13e-12	1459	111	32	GO:0000977
GeneOntologyMolecularFunction	zinc ion binding	ADAMTS1 ENPP1 DBF4B UBR4 NSD1 ZMYM2 TUT1 ADAMTS8 CREBBP CRIP1 USP20 ZBBX PARP1 RNF2 ADAMTS9 LNPEP TRIM17 NFXL1 TNKS ALB EP300 USP33	3.29e-09	891	111	22	GO:0008270
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF823 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF66 NFXL1 ZNF737 ZNF30 ZNF705B MGA NOTCH1	1.00e-08	1412	111	27	GO:0000981
GeneOntologyMolecularFunction	transition metal ion binding	ADAMTS1 ENPP1 DBF4B UBR4 NSD1 ZMYM2 TUT1 ADAMTS8 CREBBP CRIP1 USP20 ZBBX PARP1 RNF2 ADAMTS9 LNPEP TRIM17 NFXL1 TNKS ALB EP300 USP33	5.33e-07	1189	111	22	GO:0046914
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF274 ZNF473 ZNF174 NSD1 ZNF213 ZNF226 REST PREB ZNF708 ZNF605 SALL1 ZNF334 GLI1 ZNF197 ZNF66 ZNF737 NLRC5 ZNF30 MGA EP300 NOTCH1	6.02e-06	1271	111	21	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF274 ZNF473 ZNF174 NSD1 ZNF213 ZNF226 REST PREB ZNF708 ZNF605 SALL1 ZNF334 GLI1 ZNF197 ZNF66 ZNF737 NLRC5 ZNF30 MGA EP300	1.55e-05	1244	111	20	GO:0000978
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	3.06e-05	2	111	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	3.06e-05	2	111	2	GO:0044017
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	5.63e-05	120	111	6	GO:0004222
GeneOntologyMolecularFunction	chromatin binding	ZNF274 NSD1 REST CREBBP MSL2 RING1 PARP1 SALL1 RNF2 GLI1 PRDM14 EP300 NOTCH1 BAHCC1	6.07e-05	739	111	14	GO:0003682
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	9.15e-05	3	111	2	GO:0043993
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9 LNPEP	1.28e-04	200	111	7	GO:0008237
GeneOntologyMolecularFunction	dinucleotide phosphatase activity	CILP ENPP1	1.07e-03	9	111	2	GO:0004551
GeneOntologyMolecularFunction	transcription regulator activator activity	PARP1 NOTCH1	1.34e-03	10	111	2	GO:0140537
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP GLI1 EP300	1.18e-07	3	26	3	HP:0005895
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	2.51e-05	2	26	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	2.51e-05	2	26	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	2.51e-05	2	26	2	HP:0001042
HumanPheno	Urethral valve	BNC2 NSD1 SALL1	2.52e-05	12	26	3	HP:0010481
HumanPheno	Hydrocele testis	NSD1 ZMYM2 CREBBP EP300	2.81e-05	36	26	4	HP:0000034
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	7.49e-05	3	26	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	7.49e-05	3	26	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	7.49e-05	3	26	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	7.49e-05	3	26	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	7.49e-05	3	26	2	HP:0005322
HumanPheno	Vesicoureteral reflux	BNC2 NSD1 ZMYM2 CREBBP SALL1 LTBP1 EP300	8.54e-05	221	26	7	HP:0000076
HumanPheno	Trichiasis	CREBBP EP300	1.49e-04	4	26	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	1.49e-04	4	26	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	1.49e-04	4	26	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	1.49e-04	4	26	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	1.49e-04	4	26	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	1.49e-04	4	26	2	HP:0031207
HumanPheno	Abnormal ureter physiology	BNC2 NSD1 ZMYM2 CREBBP SALL1 LTBP1 EP300	1.64e-04	245	26	7	HP:0025634
HumanPheno	Brachydactyly (hand)	NSD1 ZMYM2 PHF6 CREBBP SALL1 GLI1 ASPH EP300 NOTCH1	1.70e-04	430	26	9	HP:0100667
HumanPheno	Agenesis of permanent teeth	NSD1 CREBBP EP300	1.95e-04	23	26	3	HP:0006349
HumanPheno	Broad hallux phalanx	CREBBP SALL1 EP300	2.23e-04	24	26	3	HP:0010059
HumanPheno	Aortic valve stenosis	VWF CREBBP LTBP1 EP300 NOTCH1	2.23e-04	113	26	5	HP:0001650
HumanPheno	Abnormal atrioventricular valve morphology	VWF ENPP1 CREBBP RNF2 GLI1 FHL1 EP300 NOTCH1	2.39e-04	350	26	8	HP:0006705
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	2.48e-04	5	26	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	2.48e-04	5	26	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	2.48e-04	5	26	2	HP:0030421
HumanPheno	Abnormality of the urethra	BNC2 NSD1 ZMYM2 REST CREBBP SALL1 GLI1 LTBP1 EP300	3.09e-04	465	26	9	HP:0000795
HumanPheno	Abnormal heart valve morphology	VWF ENPP1 CREBBP SALL1 RNF2 GLI1 LTBP1 FHL1 EP300 NOTCH1	3.68e-04	588	26	10	HP:0001654
HumanPheno	Urethral obstruction	BNC2 NSD1 ZMYM2 SALL1	3.68e-04	69	26	4	HP:0000796
HumanPheno	Large foramen magnum	CREBBP EP300	3.71e-04	6	26	2	HP:0002700
HumanPheno	Abnormality of the ureter	BNC2 NSD1 ZMYM2 CREBBP SALL1 GLI1 LTBP1 EP300	4.44e-04	383	26	8	HP:0000069
HumanPheno	Deviated nasal septum	CREBBP EP300	5.18e-04	7	26	2	HP:0004411
HumanPheno	Tethered cord	ZMYM2 CREBBP SALL1	5.31e-04	32	26	3	HP:0002144
HumanPheno	Abnormal conus terminalis morphology	ZMYM2 CREBBP SALL1	5.82e-04	33	26	3	HP:0031938
HumanPheno	Abnormal heart valve physiology	VWF ENPP1 CREBBP RNF2 LTBP1 FHL1 EP300 NOTCH1	6.26e-04	403	26	8	HP:0031653
HumanPheno	Short phalanx of finger	NSD1 PHF6 CREBBP SALL1 GLI1 EP300 NOTCH1	6.42e-04	306	26	7	HP:0009803
HumanPheno	Abnormal scrotum morphology	PHF6 REST CREBBP SALL1 EP300	6.64e-04	143	26	5	HP:0000045
HumanPheno	Abnormal number of permanent teeth	NSD1 CREBBP EP300	6.93e-04	35	26	3	HP:0011044
HumanPheno	Hypoplastic toenails	NSD1 ZMYM2 GLI1 NOTCH1	7.12e-04	82	26	4	HP:0001800
HumanPheno	Abnormal mitral valve morphology	VWF ENPP1 CREBBP EP300 NOTCH1	7.30e-04	146	26	5	HP:0031477
HumanPheno	Abnormality of the distal phalanx of the thumb	CREBBP GLI1 EP300	7.54e-04	36	26	3	HP:0009617
HumanPheno	Aplasia/Hypoplasia of the phalanges of the hand	NSD1 PHF6 CREBBP SALL1 GLI1 EP300 NOTCH1	8.25e-04	319	26	7	HP:0009767
HumanPheno	Congenital posterior urethral valve	BNC2 NSD1	8.82e-04	9	26	2	HP:0010957
HumanPheno	Pilomatrixoma	CREBBP EP300	8.82e-04	9	26	2	HP:0030434
HumanPheno	Cervical cord compression	CREBBP EP300	8.82e-04	9	26	2	HP:0002341
HumanPheno	Broad toe	ZMYM2 CREBBP ASPH EP300	8.91e-04	87	26	4	HP:0001837
HumanPheno	Short finger	ZMYM2 PHF6 CREBBP GLI1 ASPH EP300 NOTCH1	9.22e-04	325	26	7	HP:0009381
HumanPheno	Poor coordination	NSD1 CREBBP EP300	9.55e-04	39	26	3	HP:0002370
HumanPheno	Broad thumb	NSD1 CREBBP SALL1 EP300	1.01e-03	90	26	4	HP:0011304
HumanPheno	Abnormality of the joints of the lower limbs	ENPP1 NSD1 MCOLN1 CREBBP SALL1 GLI1 LTBP1 FHL1 EP300	1.03e-03	547	26	9	HP:0100239
HumanPheno	Brachydactyly	NSD1 ZMYM2 PHF6 CREBBP SALL1 GLI1 ASPH LTBP1 EP300 NOTCH1	1.06e-03	670	26	10	HP:0001156
HumanPheno	Short digit	NSD1 ZMYM2 PHF6 CREBBP SALL1 GLI1 ASPH LTBP1 EP300 NOTCH1	1.08e-03	672	26	10	HP:0011927
HumanPheno	Frontal hirsutism	CREBBP EP300	1.10e-03	10	26	2	HP:0011335
HumanPheno	Convex nasal ridge	CREBBP ASPH LTBP1 EP300	1.24e-03	95	26	4	HP:0000444
HumanPheno	Juvenile aseptic necrosis	PHF6 CREBBP EP300	1.27e-03	43	26	3	HP:0100323
HumanPheno	Urethrovesical occlusion	BNC2 NSD1	1.34e-03	11	26	2	HP:0034378
HumanPheno	Abnormal subclavian artery morphology	CREBBP EP300	1.34e-03	11	26	2	HP:0031251
Domain	Znf_C2H2	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 TUT1 ZNF226 REST RNF114 ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	8.41e-15	805	108	28	IPR007087
Domain	ZnF_C2H2	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 TUT1 ZNF226 REST RNF114 ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	9.23e-15	808	108	28	SM00355
Domain	zf-C2H2	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	1.58e-14	693	108	26	PF00096
Domain	Znf_C2H2-like	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST RNF114 ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	5.11e-14	796	108	27	IPR015880
Domain	-	ZNF823 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	8.44e-14	679	108	25	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF823 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	1.38e-13	694	108	25	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	2.12e-13	775	108	26	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 REST ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	2.25e-13	777	108	26	PS00028
Domain	KRAB	ZNF823 ZNF274 ZNF473 ZNF213 ZNF226 ZNF785 ZNF705D ZNF440 ZNF404 ZNF708 ZNF605 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30 ZNF705B	2.46e-11	358	108	17	PS50805
Domain	KRAB	ZNF823 ZNF274 ZNF473 ZNF213 ZNF226 ZNF785 ZNF705D ZNF440 ZNF404 ZNF708 ZNF605 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30 ZNF705B	2.46e-11	358	108	17	PF01352
Domain	KRAB	ZNF823 ZNF274 ZNF473 ZNF213 ZNF226 ZNF785 ZNF705D ZNF440 ZNF404 ZNF708 ZNF605 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30 ZNF705B	3.96e-11	369	108	17	SM00349
Domain	KRAB	ZNF823 ZNF274 ZNF473 ZNF213 ZNF226 ZNF785 ZNF705D ZNF440 ZNF404 ZNF708 ZNF605 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30 ZNF705B	4.13e-11	370	108	17	IPR001909
Domain	Peptidase_M12B_N	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	9.08e-08	39	108	6	IPR002870
Domain	Pep_M12B_propep	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	9.08e-08	39	108	6	PF01562
Domain	DISINTEGRIN_1	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.06e-07	40	108	6	PS00427
Domain	Reprolysin	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.06e-07	40	108	6	PF01421
Domain	ADAM_MEPRO	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.06e-07	40	108	6	PS50215
Domain	DISINTEGRIN_2	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.06e-07	40	108	6	PS50214
Domain	Peptidase_M12B	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.06e-07	40	108	6	IPR001590
Domain	Disintegrin_dom	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	1.24e-07	41	108	6	IPR001762
Domain	zf-C2H2_6	ZNF823 ZNF473 PEG3 ZNF440 ZNF404 ZBTB44 ZNF605 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30	2.73e-07	314	108	12	PF13912
Domain	ACR	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8	4.30e-07	27	108	5	SM00608
Domain	ADAM_Cys-rich	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8	4.30e-07	27	108	5	IPR006586
Domain	TSP_1	THSD7A CILP ADAMTS1 ADAMTS8 THBS1 ADAMTS9	1.69e-06	63	108	6	PF00090
Domain	TSP1	THSD7A CILP ADAMTS1 ADAMTS8 THBS1 ADAMTS9	2.04e-06	65	108	6	SM00209
Domain	TSP1_rpt	THSD7A CILP ADAMTS1 ADAMTS8 THBS1 ADAMTS9	2.04e-06	65	108	6	IPR000884
Domain	TSP1	THSD7A CILP ADAMTS1 ADAMTS8 THBS1 ADAMTS9	2.04e-06	65	108	6	PS50092
Domain	MetalloPept_cat_dom	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	7.42e-06	81	108	6	IPR024079
Domain	-	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9	7.42e-06	81	108	6	3.40.390.10
Domain	-	RPH3AL NSD1 PHF6 G2E3 RNF114 USP20 MSL2 RING1 RNF2 TRIM17 RIMS2 USP33	1.11e-05	449	108	12	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RPH3AL NSD1 PHF6 G2E3 RNF114 USP20 MSL2 RING1 RNF2 TRIM17 RIMS2 USP33	1.39e-05	459	108	12	IPR013083
Domain	SCAN	ZNF274 ZNF174 PEG3 ZNF213 ZNF197	1.78e-05	56	108	5	SM00431
Domain	SCAN_BOX	ZNF274 ZNF174 PEG3 ZNF213 ZNF197	2.11e-05	58	108	5	PS50804
Domain	SCAN	ZNF274 ZNF174 PEG3 ZNF213 ZNF197	2.11e-05	58	108	5	PF02023
Domain	SCAN_dom	ZNF274 ZNF174 PEG3 ZNF213 ZNF197	2.11e-05	58	108	5	IPR003309
Domain	ZINC_PROTEASE	ADAMTS1 ADAM20 ADAM29 ADAMTS8 ADAMTS9 LNPEP	2.22e-05	98	108	6	PS00142
Domain	Retrov_capsid_C	ZNF274 ZNF174 PEG3 ZNF213 ZNF197	2.30e-05	59	108	5	IPR008916
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	3.31e-05	2	108	2	IPR014744
Domain	HAT_KAT11	CREBBP EP300	3.31e-05	2	108	2	PF08214
Domain	KIX	CREBBP EP300	3.31e-05	2	108	2	PS50952
Domain	ZnF_TAZ	CREBBP EP300	3.31e-05	2	108	2	SM00551
Domain	CBP_P300_HAT	CREBBP EP300	3.31e-05	2	108	2	IPR031162
Domain	DUF902	CREBBP EP300	3.31e-05	2	108	2	PF06001
Domain	-	CREBBP EP300	3.31e-05	2	108	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	3.31e-05	2	108	2	IPR010303
Domain	-	CREBBP EP300	3.31e-05	2	108	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	3.31e-05	2	108	2	PF09030
Domain	-	CREBBP EP300	3.31e-05	2	108	2	1.10.246.20
Domain	zf-TAZ	CREBBP EP300	3.31e-05	2	108	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	3.31e-05	2	108	2	PS50134
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	3.31e-05	2	108	2	IPR013178
Domain	KAT11	CREBBP EP300	3.31e-05	2	108	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	3.31e-05	2	108	2	IPR000197
Domain	KIX_dom	CREBBP EP300	3.31e-05	2	108	2	IPR003101
Domain	KIX	CREBBP EP300	3.31e-05	2	108	2	PF02172
Domain	CBP_P300_HAT	CREBBP EP300	3.31e-05	2	108	2	PS51727
Domain	Disintegrin_CS	ADAM20 ADAM7 ADAM29	9.97e-05	16	108	3	IPR018358
Domain	EGF_1	ADAM20 ADAM29 MUC12 MUC13 THBS1 NTNG2 LTBP1 NOTCH1	1.17e-04	255	108	8	PS00022
Domain	EGF-like_CS	ADAM20 ADAM29 MUC12 MUC13 THBS1 NTNG2 LTBP1 NOTCH1	1.38e-04	261	108	8	IPR013032
Domain	ADAM_CR	ADAM20 ADAM7 ADAM29	1.44e-04	18	108	3	PF08516
Domain	EGF_2	ADAM20 ADAM29 MUC12 MUC13 THBS1 NTNG2 LTBP1 NOTCH1	1.53e-04	265	108	8	PS01186
Domain	-	ADAM20 ADAM7 ADAM29	2.00e-04	20	108	3	4.10.70.10
Domain	Disintegrin	ADAM20 ADAM7 ADAM29	2.32e-04	21	108	3	PF00200
Domain	DISIN	ADAM20 ADAM7 ADAM29	2.32e-04	21	108	3	SM00050
Domain	ADAM_spacer1	ADAMTS1 ADAMTS8 ADAMTS9	3.06e-04	23	108	3	IPR010294
Domain	ADAM_spacer1	ADAMTS1 ADAMTS8 ADAMTS9	3.06e-04	23	108	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS1 ADAMTS8 ADAMTS9	3.48e-04	24	108	3	IPR013273
Domain	C2H2_Znf_fam	ZNF174 PEG3 REST	3.48e-04	24	108	3	IPR027775
Domain	EGF_3	ADAM20 ADAM29 MUC13 THBS1 NTNG2 LTBP1 NOTCH1	4.33e-04	235	108	7	PS50026
Domain	DUSP	USP20 USP33	4.89e-04	6	108	2	SM00695
Domain	Nuc_rcpt_coact	CREBBP EP300	4.89e-04	6	108	2	IPR009110
Domain	DUSP	USP20 USP33	4.89e-04	6	108	2	PF06337
Domain	EGF-like_dom	ADAM20 ADAM29 MUC13 THBS1 NTNG2 LTBP1 NOTCH1	6.12e-04	249	108	7	IPR000742
Domain	Znf_RING	NSD1 G2E3 RNF114 MSL2 RING1 RNF2 TRIM17 NFXL1	6.13e-04	326	108	8	IPR001841
Domain	-	USP20 USP33	6.83e-04	7	108	2	3.30.2230.10
Domain	RAWUL	RING1 RNF2	6.83e-04	7	108	2	IPR032443
Domain	DUSP	USP20 USP33	6.83e-04	7	108	2	PS51283
Domain	Pept_C19_DUSP	USP20 USP33	6.83e-04	7	108	2	IPR006615
Domain	RAWUL	RING1 RNF2	6.83e-04	7	108	2	PF16207
Domain	LIM	LMO3 CRIP1 PXN FHL1	6.85e-04	69	108	4	PF00412
Domain	-	LMO3 CRIP1 PXN FHL1	7.23e-04	70	108	4	2.10.110.10
Domain	Znf_LIM	LMO3 CRIP1 PXN FHL1	7.63e-04	71	108	4	IPR001781
Domain	LIM_DOMAIN_1	LMO3 CRIP1 PXN FHL1	7.63e-04	71	108	4	PS00478
Domain	LIM_DOMAIN_2	LMO3 CRIP1 PXN FHL1	7.63e-04	71	108	4	PS50023
Domain	LIM	LMO3 CRIP1 PXN FHL1	7.63e-04	71	108	4	SM00132
Domain	Znf_FYVE_PHD	RPH3AL NSD1 G2E3 RIMS2 PRDM14	1.64e-03	147	108	5	IPR011011
Domain	SET	NSD1 SMYD2 PRDM14	1.71e-03	41	108	3	PF00856
Domain	FYVE_2	RPH3AL RIMS2	1.76e-03	11	108	2	PF02318
Domain	ZnF_UBP	USP20 USP33	1.76e-03	11	108	2	SM00290
Domain	RABBD	RPH3AL RIMS2	2.11e-03	12	108	2	PS50916
Domain	Rab_BD	RPH3AL RIMS2	2.11e-03	12	108	2	IPR010911
Domain	SET	NSD1 SMYD2 PRDM14	2.38e-03	46	108	3	SM00317
Domain	Znf_UBP	USP20 USP33	2.88e-03	14	108	2	IPR001607
Domain	zf-UBP	USP20 USP33	2.88e-03	14	108	2	PF02148
Domain	ZF_UBP	USP20 USP33	2.88e-03	14	108	2	PS50271
Domain	SET_dom	NSD1 SMYD2 PRDM14	3.03e-03	50	108	3	IPR001214
Domain	SET	NSD1 SMYD2 PRDM14	3.03e-03	50	108	3	PS50280
Domain	Quinoprotein_ADH-like_supfam	WDR7 EML6 PREB	3.57e-03	53	108	3	IPR011047
Domain	Poly(ADP-ribose)pol_cat_dom	PARP1 TNKS	4.26e-03	17	108	2	IPR012317
Domain	PARP_CATALYTIC	PARP1 TNKS	4.26e-03	17	108	2	PS51059
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD7A ADAMTS1 MUC12 ADAMTS8 MUC13 THBS1 ADAMTS9 NOTCH1	4.22e-09	68	80	8	M27303
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF274 ZNF473 ZNF213 ZNF226 REST TNFRSF10A CREBBP ZNF785 ZNF705D SMYD2 ZNF440 RING1 ZNF708 PARP1 THBS1 ZNF605 RNF2 ZNF334 ZNF425 ZNF197 ZNF737 ZNF30 MGA EP300 NOTCH1	9.39e-08	1387	80	25	M734
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD7A ADAMTS1 MUC12 ADAMTS8 MUC13 THBS1 ADAMTS9 NOTCH1	1.44e-06	143	80	8	M27275
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS1 ADAMTS8 THBS1 ADAMTS9	2.57e-06	39	80	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS1 ADAMTS8 THBS1 ADAMTS9	2.57e-06	39	80	5	MM15165
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A ADAMTS1 MUC12 ADAMTS8 MUC13 THBS1 ADAMTS9	3.07e-06	111	80	7	M27416
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300 NOTCH1	9.66e-06	8	80	3	M48024
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300 NOTCH1	2.81e-05	11	80	3	M48021
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	NSD1 CREBBP MGA EP300 NOTCH1	3.28e-05	65	80	5	M39682
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A ADAMTS1 ADAMTS8 MUC13 THBS1 ADAMTS9	3.51e-05	109	80	6	MM15164
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	THSD7A ADAMTS1 MUC12 ADAMTS8 MUC13 CREBBP USP20 RING1 PREB PARP1 THBS1 NTNG2 RNF2 ADAMTS9 ASPH TNKS LTBP1 ALB EP300 USP33 VCPIP1	5.23e-05	1475	80	21	M19806
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP EP300 NOTCH1	6.12e-05	14	80	3	M27808
Pathway	KEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27	RING1 RNF2 EP300	7.62e-05	15	80	3	M47973
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD7A ADAMTS1 MUC12 ADAMTS8 MUC13 THBS1 ADAMTS9 NOTCH1	8.43e-05	250	80	8	M27554
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP EP300 NOTCH1	9.34e-05	16	80	3	M27121
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	CREBBP RING1 RNF2 EP300	1.10e-04	44	80	4	M27295
Pathway	PID_HES_HEY_PATHWAY	CREBBP PARP1 EP300 NOTCH1	1.55e-04	48	80	4	M288
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300 NOTCH1	1.87e-04	20	80	3	M27881
Pathway	WP_TGFBETA_SIGNALING_PATHWAY	CREBBP THBS1 LTBP1 EP300	2.28e-04	53	80	4	MM15880
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING	CREBBP THBS1 LTBP1 EP300	2.63e-04	55	80	4	M39351
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	ZMYM2 REST CREBBP PARP1 SALL1 RNF2 EP300 NOTCH1	3.01e-04	301	80	8	MM15983
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	3.15e-04	5	80	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	3.15e-04	5	80	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	3.15e-04	5	80	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	3.15e-04	5	80	2	M27228
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	CREBBP THBS1 LTBP1 EP300	3.45e-04	59	80	4	M39886
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	RING1 RNF2 MGA	3.70e-04	25	80	3	MM15546
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300 NOTCH1	3.70e-04	25	80	3	M27880
Pathway	WP_NOTCH_SIGNALING_WP61	RING1 FHL1 EP300 NOTCH1	3.93e-04	61	80	4	M39540
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES	RING1 RNF2 MGA	4.67e-04	27	80	3	M47941
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	4.70e-04	6	80	2	M22062
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	6.56e-04	7	80	2	MM1573
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	8.71e-04	8	80	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	8.71e-04	8	80	2	M48022
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	8.71e-04	8	80	2	M46443
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	RING1 RNF2 EP300	9.28e-04	34	80	3	MM15531
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	RING1 RNF2 MGA	9.28e-04	34	80	3	M27826
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	1.12e-03	9	80	2	M47451
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	RING1 RNF2 EP300	1.19e-03	37	80	3	M27797
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	RING1 FHL1 EP300 NOTCH1	1.20e-03	82	80	4	MM15922
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF823 ZNF473 ZNF213 ZNF226 SMYD2 RING1 PARP1 ZNF605 RNF2 MGA EP300 NOTCH1	1.24e-03	768	80	12	MM14851
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	EP300 NOTCH1	1.39e-03	10	80	2	MM15535
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	CREBBP EP300	1.39e-03	10	80	2	M27945
Pathway	KEGG_TGF_BETA_SIGNALING_PATHWAY	CREBBP THBS1 LTBP1 EP300	1.44e-03	86	80	4	M2642
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	RING1 RNF2 EP300	1.49e-03	40	80	3	MM15000
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	1.69e-03	11	80	2	MM1521
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	1.69e-03	11	80	2	M26924
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	CREBBP EP300 NOTCH1	1.72e-03	42	80	3	M17541
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	THSD7A ADAMTS1 ADAMTS8 MUC13 USP20 RING1 PREB PARP1 THBS1 RNF2 ADAMTS9 TNKS LTBP1 ALB EP300 USP33 VCPIP1	1.76e-03	1389	80	17	MM15307
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	2.02e-03	12	80	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	2.02e-03	12	80	2	M27765
Pathway	KEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2	RING1 RNF2	2.02e-03	12	80	2	M47943
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	CREBBP EP300 NOTCH1	2.38e-03	47	80	3	M7946
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300 NOTCH1	2.53e-03	48	80	3	M611
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	VWF ZNF473 ADAMTS1 UBR4 PEG3 ZMYM2 LMO3 ADAMTS8 CREBBP ZNF785 SMYD2 ZBTB44 PARP1 THBS1 ZNF605 ZNF334 ADAMTS9 SULF1 ZNF197 TNKS FHL1 DNAJA1 EP300 USP33 VCPIP1	4.23e-13	1285	113	25	35914814
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NSD1 ZMYM2 KIF4A G2E3 REST MSL2 RING1 PREB ZBTB44 PARP1 RNF2 ASPH NFXL1 RACGAP1 MGA DNAJA1 EP300 VCPIP1	1.97e-07	1294	113	18	30804502
Pubmed	NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.	CREBBP RING1 RNF2 EP300	2.43e-07	17	113	4	34637754
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF274 ZNF174 PEG3 TUT1 ZNF226 REST RNF114 CREBBP ZBBX RING1 GLI1 PXN FHL1	5.58e-07	709	113	13	22988430
Pubmed	Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.	CREBBP FHL1 EP300	6.63e-07	6	113	3	22219185
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR4 ZMYM2 KIF4A CREBBP SMYD2 SALL1 RNF2 GLI1 NFXL1 ALB FHL1 MGA EP300 NOTCH1	7.87e-07	857	113	14	25609649
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZNF274 ZNF473 ZNF174 ZMYM2 LMO3 ZNF226 REST CREBBP ZNF440 PREB PARP1 GLI1 PRDM14 EP300	1.03e-06	877	113	14	20211142
Pubmed	REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements.	REST RING1 RNF2	1.16e-06	7	113	3	21402785
Pubmed	Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.	ADAMTS1 ADAMTS9 NOTCH1	2.77e-06	9	113	3	23095891
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ADAMTS1 TNFRSF10A PREB ASPH PCNX1 TSTD2 PAN3 DNAJA1 BAHCC1	3.66e-06	371	113	9	15747579
Pubmed	A human MAP kinase interactome.	ZNF823 VWF ZMYM2 MUC12 CREBBP ZNF440 MSL2 MGA EP300 GAREM1	4.45e-06	486	113	10	20936779
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD7A ADAMTS1 ADAMTS8 THBS1 ADAMTS9	4.77e-06	75	113	5	20637190
Pubmed	The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.	REST RING1 RNF2	5.41e-06	11	113	3	17468742
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	VWF PEG3 SHB ZBTB44 RNF2 ADAMTS9 PXN TNKS FHL1 MGA	5.42e-06	497	113	10	23414517
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	CREBBP PARP1 SALL1 TNKS ALB MGA DNAJA1 EP300 BAHCC1	6.44e-06	398	113	9	35016035
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	BNC2 ZMYM2 SALL1 RNF2 MGA DNAJA1	8.62e-06	146	113	6	23892456
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ZNF174 PHF6 KIF4A ZNF226 CREBBP RING1 RACGAP1 LTBP1 ALB EP300 VCPIP1	8.62e-06	645	113	11	25281560
Pubmed	A protein interaction network for pluripotency of embryonic stem cells.	ZMYM2 REST SALL1 RNF2	9.75e-06	41	113	4	17093407
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.05e-05	2	113	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.05e-05	2	113	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.05e-05	2	113	2	19729597
Pubmed	Polycomb directs timely activation of germline genes in spermatogenesis.	RING1 RNF2	1.05e-05	2	113	2	28924034
Pubmed	Macrophage-released ADAMTS1 promotes muscle stem cell activation.	ADAMTS1 NOTCH1	1.05e-05	2	113	2	28939843
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.05e-05	2	113	2	39287984
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.05e-05	2	113	2	20717166
Pubmed	Nonleukemic T/B mixed phenotype acute leukemia with PHF6 and NOTCH1 mutations.	PHF6 NOTCH1	1.05e-05	2	113	2	34473233
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.05e-05	2	113	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.05e-05	2	113	2	11559821
Pubmed	Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension.	PXN FHL1	1.05e-05	2	113	2	22959909
Pubmed	ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2.	ADAMTS1 THBS1	1.05e-05	2	113	2	17082774
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.05e-05	2	113	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.05e-05	2	113	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.05e-05	2	113	2	24522976
Pubmed	Polycomb function during oogenesis is required for mouse embryonic development.	RING1 RNF2	1.05e-05	2	113	2	22499591
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.05e-05	2	113	2	21847097
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.05e-05	2	113	2	34813504
Pubmed	Modeling ADAMTS13-von Willebrand factor interaction: Implications for oxidative stress-related cardiovascular diseases and type 2A von Willebrand disease.	VWF ADAMTS1	1.05e-05	2	113	2	21937160
Pubmed	METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.	ADAMTS1 ADAMTS8	1.05e-05	2	113	2	10438512
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.05e-05	2	113	2	20301699
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.05e-05	2	113	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.05e-05	2	113	2	37816914
Pubmed	Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice.	VWF THBS1	1.05e-05	2	113	2	14981081
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	1.05e-05	2	113	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	1.05e-05	2	113	2	10918613
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	1.05e-05	2	113	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	1.05e-05	2	113	2	31898871
Pubmed	NOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT study.	CREBBP NOTCH1	1.05e-05	2	113	2	37864465
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	1.05e-05	2	113	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	1.05e-05	2	113	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	1.05e-05	2	113	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	1.05e-05	2	113	2	32690000
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	1.05e-05	2	113	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	1.05e-05	2	113	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	1.05e-05	2	113	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	1.05e-05	2	113	2	24089570
Pubmed	Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice.	VWF THBS1	1.05e-05	2	113	2	25343959
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	1.05e-05	2	113	2	15706485
Pubmed	The role of ADAMTS genes in the end stage of hip osteoarthritis.	ADAMTS1 ADAMTS8	1.05e-05	2	113	2	30655094
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	1.05e-05	2	113	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	1.05e-05	2	113	2	22303793
Pubmed	Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.	USP20 USP33	1.05e-05	2	113	2	33792613
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	1.05e-05	2	113	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	1.05e-05	2	113	2	34019788
Pubmed	Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population.	VWF THBS1	1.05e-05	2	113	2	21518247
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	1.05e-05	2	113	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	1.05e-05	2	113	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	1.05e-05	2	113	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	1.05e-05	2	113	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	1.05e-05	2	113	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	1.05e-05	2	113	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	1.05e-05	2	113	2	30135524
Pubmed	Thrombospondin-1 in von Willebrand factor function.	VWF THBS1	1.05e-05	2	113	2	18855616
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	1.05e-05	2	113	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	1.05e-05	2	113	2	29217654
Pubmed	TNFRSF10A-LOC389641 rs13278062 but not REST-C4orf14-POLR2B-IGFBP7 rs1713985 was found associated with age-related macular degeneration in a Chinese population.	REST TNFRSF10A	1.05e-05	2	113	2	24235014
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	1.05e-05	2	113	2	10049825
Pubmed	Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.	RING1 RNF2	1.05e-05	2	113	2	18037880
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	1.05e-05	2	113	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	1.05e-05	2	113	2	29170789
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	1.05e-05	2	113	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	1.05e-05	2	113	2	12646247
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	1.05e-05	2	113	2	11867645
Pubmed	Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.	ADAM7 ADAM29	1.05e-05	2	113	2	21618342
Pubmed	Abnormal expressions of ADAMTS-1, ADAMTS-9 and progesterone receptors are associated with lower oocyte maturation in women with polycystic ovary syndrome.	ADAMTS1 ADAMTS9	1.05e-05	2	113	2	30446843
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	1.05e-05	2	113	2	11963968
Pubmed	Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5).	KCNA5 FHL1	1.05e-05	2	113	2	22053194
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	1.05e-05	2	113	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	1.05e-05	2	113	2	12696060
Pubmed	ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors.	ADAMTS1 THBS1	1.05e-05	2	113	2	20546609
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	1.05e-05	2	113	2	36109165
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	1.05e-05	2	113	2	12242694
Pubmed	Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice.	RING1 RNF2	1.05e-05	2	113	2	11060235
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	1.05e-05	2	113	2	31182547
Pubmed	Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.	CREBBP EP300	1.05e-05	2	113	2	30635043
Pubmed	Four and a half LIM protein 1: a partner for KCNA5 in human atrium.	KCNA5 FHL1	1.05e-05	2	113	2	18281375
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	1.05e-05	2	113	2	27648933
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	1.05e-05	2	113	2	10610021
Pubmed	Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.	CREBBP EP300	1.05e-05	2	113	2	37314181
Pubmed	Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.	CREBBP EP300	1.05e-05	2	113	2	12397173
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	1.05e-05	2	113	2	15641773
Interaction	ERG interactions	UBR4 ZMYM2 CREBBP RING1 ZBTB44 PARP1 RNF2 DNAJA1 EP300	3.73e-06	223	110	9	int:ERG
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF823 BNC2 ZNF274 ZNF473 ZNF174 PEG3 ZNF213 ZNF226 ZNF785 ZNF491 ZNF705D ZNF440 ZNF404 ZNF708 ZBTB44 ZNF605 SALL1 ZNF334 ZNF425 GLI1 ZNF197 ZNF737 ZNF30 ZNF705B PRDM14	4.74e-15	718	89	25	28
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS8 ADAMTS9	1.06e-04	19	89	3	50
GeneFamily	LIM domain containing	LMO3 CRIP1 PXN FHL1	2.03e-04	59	89	4	1218
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM20 ADAM7 ADAM29	3.10e-04	27	89	3	47
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	3.11e-03	17	89	2	486
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP1 TNKS	3.11e-03	17	89	2	684
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	3.48e-03	18	89	2	91
GeneFamily	CD molecules\|Mucins	MUC12 MUC13	4.73e-03	21	89	2	648
GeneFamily	Ankyrin repeat domain containing	DZANK1 DGKI TNKS NOTCH1 ARAP2	6.88e-03	242	89	5	403
Coexpression	NABA_MATRISOME	VWF CILP ADAMTS1 ADAM20 ADAM7 CXCL14 ADAM29 MUC12 ADAMTS8 MUC13 THBS1 NTNG2 ADAMTS9 SULF1 SLPI LTBP1	4.69e-06	1026	108	16	M5889
Coexpression	NABA_ECM_REGULATORS	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9 SULF1 SLPI	6.62e-06	238	108	8	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS1 ADAM20 ADAM7 ADAM29 ADAMTS8 ADAMTS9 SULF1 SLPI	7.48e-06	242	108	8	MM17062
Coexpression	GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN	ADAMTS1 PHF6 TUT1 REST SMYD2 PAN3 VCPIP1	1.23e-05	186	108	7	M8175
Coexpression	NABA_MATRISOME	VWF CILP ADAMTS1 ADAM20 ADAM7 CXCL14 ADAM29 ADAMTS8 MUC13 THBS1 NTNG2 ADAMTS9 SULF1 SLPI LTBP1	1.66e-05	1008	108	15	MM17056
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	ZNF823 BNC2 THSD7A PEG3 PHF6 CXCL14 LMO3 ZBTB44 THBS1 SALL1 RNF2 LNPEP SULF1 ASPH LTBP1 VCPIP1	4.39e-06	836	107	16	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 CXCL14 LMO3 ZNF491 SALL1 GLI1 LTBP1 FHL1	1.47e-08	173	113	8	f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 CXCL14 LMO3 ZNF491 SALL1 ZNF334 GLI1 LTBP1	1.76e-08	177	113	8	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 CILP ADAMTS1 CXCL14 LMO3 THBS1 GLI1 DGKI	2.49e-08	185	113	8	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ADAMTS8 THBS1 KCNA5 ADAMTS9 LTBP1 FHL1	7.74e-07	199	113	7	8ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 ENPP1 UBR4 CXCL14 THBS1 FHL1 ALPK2	8.01e-07	200	113	7	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC2 THSD7A MUC13 SULF1 SLPI LTBP1	6.68e-06	180	113	6	3d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC2 THSD7A MUC13 SULF1 SLPI LTBP1	6.68e-06	180	113	6	47e345359064dc8ceec982b062e47802e728b43f
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ADAMTS1 KIF4A ZNF785 ZNF334 ADAMTS9	6.68e-06	180	113	6	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCL14 LMO3 P2RX1 GLI1 LTBP1 FHL1	7.35e-06	183	113	6	6b5eef96b28911c752a8b6c0975918c4572cec38
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 CXCL14 SALL1 GLI1 LTBP1 FHL1	7.35e-06	183	113	6	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THSD7A PEG3 NTNG2 DGKI ALB CYTH4	7.58e-06	184	113	6	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 MUC13 CRIP1 SULF1 GLI1 FHL1	7.82e-06	185	113	6	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF THSD7A TNFRSF10A SSUH2 SULF1 LTBP1	8.06e-06	186	113	6	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	NS-critical-d_07-13-Epithelial-IRC-IFNG_responsive_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	THSD7A CXCL14 MUC13 THBS1 SLPI DGKI	8.57e-06	188	113	6	6ee2e7fa80f48e4a7f3321b0776a4f697469bc61
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 ADAMTS1 CXCL14 ADAMTS8 LTBP1 FHL1	8.83e-06	189	113	6	ab7ece0a517499b70b7754720d3e434765363af6
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF THSD7A ADAMTS1 MUC13 SSUH2 SULF1	8.83e-06	189	113	6	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP ADAMTS1 CXCL14 LMO3 THBS1 SLPI	9.38e-06	191	113	6	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	VWF THSD7A ADAMTS1 SULF1 SLPI LTBP1	9.66e-06	192	113	6	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 CXCL14 SALL1 GLI1 LTBP1 FHL1	9.95e-06	193	113	6	146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCell	ILEUM-inflamed-(8)_Smooth_muscle_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CXCL14 ADAMTS8 SULF1 GLI1 LTBP1 FHL1	9.95e-06	193	113	6	084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	BNC2 VWF ADAMTS1 SALL1 ADAMTS9 DGKI	1.02e-05	194	113	6	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 CXCL14 THBS1 ASPH SLPI DNAJA1	1.06e-05	195	113	6	f41a68b7c2621594db8d8952e301eeadc96be26f
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|myeloid / Lineage, cell class and subclass	LINC00482 CRIP1 THBS1 PXN PCNX1 NOTCH1	1.06e-05	195	113	6	15ba9c5f6ecb6ae2c603e6b036eb92b00b46f13f
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF THSD7A ADAMTS1 SSUH2 SULF1 LTBP1	1.09e-05	196	113	6	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADAMTS1 ADAMTS8 THBS1 TRIM17 LTBP1 FHL1	1.12e-05	197	113	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VWF THSD7A ADAMTS1 SSUH2 ADAMTS9 SULF1	1.12e-05	197	113	6	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 EML6 THBS1 KCNA5 ADAMTS9 LTBP1	1.15e-05	198	113	6	f261a37dd07976548b897af86df1d1a0dc069889
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 ADAMTS8 THBS1 KCNA5 LTBP1 FHL1	1.15e-05	198	113	6	c82a151f9f1477d4a401457173b8d72af776c137
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 ADAMTS8 THBS1 KCNA5 LTBP1 FHL1	1.15e-05	198	113	6	dc63b56bb6291e527b172d603569376286262845
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ADAMTS8 THBS1 KCNA5 ADAMTS9 FHL1	1.18e-05	199	113	6	0a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CILP ENPP1 CXCL14 LMO3 LTBP1 FHL1	1.18e-05	199	113	6	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BNC2 ADAMTS1 ADAMTS8 THBS1 LTBP1 FHL1	1.18e-05	199	113	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ADAMTS8 THBS1 KCNA5 ADAMTS9 LTBP1	1.18e-05	199	113	6	c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VWF THSD7A ADAMTS1 SSUH2 ADAMTS9 SULF1	1.22e-05	200	113	6	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 KCNA5 ADAMTS9 SULF1 LTBP1 FHL1	1.22e-05	200	113	6	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	VWF THSD7A TNFRSF10A SSUH2 SULF1 LTBP1	1.22e-05	200	113	6	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	VWF THSD7A ADAMTS1 SSUH2 SULF1 LTBP1	1.22e-05	200	113	6	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VWF THSD7A ADAMTS1 SSUH2 SULF1 LTBP1	1.22e-05	200	113	6	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 ADAMTS1 ADAMTS8 THBS1 LTBP1 FHL1	1.22e-05	200	113	6	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	VWF THSD7A ADAMTS1 SSUH2 SULF1 LTBP1	1.22e-05	200	113	6	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF RPH3AL LINC00482 TNFRSF10A SSUH2	4.18e-05	151	113	5	3b4c57bad61e17a573e6f8dc6b917fba5fd56c43
ToppCell	367C-Fibroblasts-Fibroblast-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 ADAM29 GLI1 LTBP1 FHL1	4.59e-05	154	113	5	dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell	367C-Fibroblasts-Fibroblast-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	CXCL14 ADAM29 GLI1 LTBP1 FHL1	4.59e-05	154	113	5	4bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF THSD7A KCNA5 SULF1 DGKI	5.84e-05	162	113	5	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BNC2 LMO3 THBS1 SALL1 DGKI	6.55e-05	166	113	5	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PEG3 SKIDA1 LMO3 ADAMTS8 KCNA5	6.55e-05	166	113	5	68e6fc7c0040bbe48a93f96ecf28afffdc626845
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 VWF THSD7A ADAMTS1 ADAMTS9	7.33e-05	170	113	5	1a568efcff9c39b3f709b55a05d24710450a2657
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 VWF THSD7A ADAMTS1 ADAMTS9	7.33e-05	170	113	5	66d41d794790e621d72ac37af995510537103c9c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF4A CXCL14 SALL1 SULF1 RACGAP1	7.33e-05	170	113	5	a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	BNC2 VWF LMO3 THBS1 DGKI	7.75e-05	172	113	5	04fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	BNC2 VWF LMO3 THBS1 DGKI	7.75e-05	172	113	5	dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 NFXL1 ALB PAN3 VCPIP1	7.96e-05	173	113	5	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 NFXL1 ALB PAN3 VCPIP1	7.96e-05	173	113	5	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 NFXL1 ALB PAN3 VCPIP1	7.96e-05	173	113	5	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 CILP KIF4A RNF2 RACGAP1	8.18e-05	174	113	5	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LINC00482 THBS1 DGKI ZNF30 CYTH4	8.40e-05	175	113	5	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 NFXL1 ALB PAN3 VCPIP1	8.40e-05	175	113	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ADAMTS8 CRIP1 KCNA5 P2RX1 LTBP1	8.63e-05	176	113	5	10c1f31c27e54b70f58f0b0086ac74dee2ce4197
ToppCell	Entopeduncular-Endothelial-MURAL\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ADAMTS8 CRIP1 KCNA5 P2RX1 LTBP1	8.63e-05	176	113	5	b8e52bec78876562a25f0b0de502aa9372b28bd2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 SKIDA1 P2RX1 ZNF30 CYTH4	8.87e-05	177	113	5	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(1)_Control_(PBS) / Stress and Cell class	ENPP1 CRIP1 NLRC5 LTBP1 DNAJA1	8.87e-05	177	113	5	d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS1 KCNA5 P2RX1 ADAMTS9 LTBP1	9.35e-05	179	113	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF THSD7A SSUH2 SULF1 LTBP1	9.35e-05	179	113	5	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	COPD-Stromal-SMC\|COPD / Disease state, Lineage and Cell class	ADAMTS1 ADAMTS8 KCNA5 ADAMTS9 LTBP1	9.35e-05	179	113	5	5c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	BNC2 VWF ADAMTS1 ADAMTS9 SULF1	9.35e-05	179	113	5	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MUC13 CRIP1 SULF1 ALB	9.35e-05	179	113	5	bc93883c2094f2e5bfed79facd4994a23968d875
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MUC13 CRIP1 SULF1 ALB	9.35e-05	179	113	5	0cef6d2eab2015cac0dd340532b24bfec9707330
ToppCell	COPD-Stromal-SMC\|World / Disease state, Lineage and Cell class	ADAMTS1 ADAMTS8 KCNA5 ADAMTS9 LTBP1	9.35e-05	179	113	5	b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCell	facs-Brain_Myeloid-Cortex-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MUC13 CRIP1 SULF1 ALB	9.35e-05	179	113	5	bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MUC13 CRIP1 SULF1 ALB	9.35e-05	179	113	5	065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ADAMTS1 SHB CRIP1 ADAMTS9	9.60e-05	180	113	5	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ADAMTS1 SHB CRIP1 ADAMTS9	9.60e-05	180	113	5	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF THSD7A SSUH2 SULF1 NOTCH1	9.85e-05	181	113	5	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF THSD7A SSUH2 ADAMTS9 NOTCH1	1.01e-04	182	113	5	0346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF THSD7A SSUH2 KCNA5 SULF1	1.01e-04	182	113	5	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF THSD7A SSUH2 KCNA5 SULF1	1.01e-04	182	113	5	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF THSD7A SSUH2 SULF1 NOTCH1	1.04e-04	183	113	5	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 PEG3 GLI1 LTBP1 FHL1	1.04e-04	183	113	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SKIDA1 MUC13 CRIP1 SULF1 FHL1	1.04e-04	183	113	5	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP CXCL14 SULF1 HFM1 FHL1	1.04e-04	183	113	5	269afec240a756eec3bbae5f30ec784281af3433
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 CRIP1 THBS1 LNPEP EP300	1.06e-04	184	113	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	VWF THSD7A ADAMTS1 SULF1 LTBP1	1.06e-04	184	113	5	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BNC2 CXCL14 CRIP1 SULF1 LTBP1	1.06e-04	184	113	5	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	VWF THSD7A ADAMTS1 ADAMTS9 LTBP1	1.06e-04	184	113	5	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCL14 LMO3 P2RX1 LTBP1 FHL1	1.06e-04	184	113	5	5cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIP1 SSUH2 THBS1 KCNA5 LTBP1	1.09e-04	185	113	5	5f5df92b328be396941b5812d00454b5ff927d30
ToppCell	droplet-Fat-Mat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ZNF174 ADAMTS8 KCNA5 RIMS2	1.09e-04	185	113	5	d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCell	droplet-Marrow-nan-18m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MUC13 SMYD2 LTBP1 FHL1	1.09e-04	185	113	5	de353368f4f6a7a0a66e391d586879876fbe2734
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZNF274 CXCL14 LMO3 ZNF708 GLI1	1.09e-04	185	113	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZNF274 CXCL14 LMO3 ZNF708 GLI1	1.09e-04	185	113	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 CRIP1 PARP1 THBS1 EP300	1.09e-04	185	113	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIP1 SSUH2 THBS1 KCNA5 LTBP1	1.09e-04	185	113	5	98547c1b1828b76da810ed86082182afaaacdb3f
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS1 ADAMTS8 THBS1 ADAMTS9 LTBP1	1.09e-04	185	113	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CILP SKIDA1 CXCL14 ADAMTS8 FHL1	1.09e-04	185	113	5	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PEG3 CXCL14 THBS1 NTNG2 FHL1	1.12e-04	186	113	5	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF THSD7A SSUH2 KCNA5 SULF1	1.12e-04	186	113	5	5302399825f213d105ac70b91366a4513b732838
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCL14 MUC12 SALL1 SULF1 LTBP1	1.12e-04	186	113	5	8ea708070166c858cd9bd871670655b0114c32a5
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	VWF THSD7A ADAMTS1 ADAMTS9 SULF1	1.15e-04	187	113	5	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	BNC2 ADAMTS1 THBS1 SULF1 LTBP1	1.15e-04	187	113	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 THSD7A ADAMTS9 DGKI RIMS2	1.15e-04	187	113	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
Drug	vinylene	ZNF274 ZNF174 PEG3 NSD1 ZNF213 REST RNF114 SALL1 GLI1 TRIM17 ZNF197 EP300	2.30e-09	245	109	12	CID000006326
Drug	Curcumin	ZNF823 VWF CXCL14 NPC2 TNFRSF10A CREBBP PARP1 THBS1 SULF1 GLI1 SLPI TNKS ALB RIMS2 EP300 NOTCH1 CYTH4	5.91e-07	850	109	17	ctd:D003474
Drug	Ethosuximide [77-67-8]; Down 200; 28.4uM; MCF7; HT_HG-U133A	CILP REST CRIP1 SLPI LTBP1 FHL1 RIMS2 BAHCC1	4.73e-06	196	109	8	2280_DN
Drug	methyl orange	ENPP1 NSD1 ALB	2.95e-05	13	109	3	CID000011037
Drug	Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A	PEG3 TUT1 ZBTB44 THBS1 ZNF197 PXN FHL1	4.19e-05	194	109	7	5075_DN
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	REST MCOLN1 USP20 DZANK1 SLPI FHL1 VCPIP1	4.33e-05	195	109	7	2820_DN
Drug	Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	ZBTB44 SALL1 ASPH SLPI PCNX1 CYTH4 BAHCC1	4.47e-05	196	109	7	2322_UP
Drug	Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A	DBF4B ADAM7 THBS1 KCNA5 FHL1 RIMS2 BAHCC1	4.47e-05	196	109	7	6781_UP
Drug	Gemfibrozil [25812-30-0]; Down 200; 16uM; MCF7; HT_HG-U133A	CILP REST SULF1 ZNF197 PCNX1 FHL1 RIMS2	4.62e-05	197	109	7	2277_DN
Drug	Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; HL60; HT_HG-U133A	BNC2 SHB TUT1 MCOLN1 LNPEP ASPH FHL1	4.62e-05	197	109	7	2131_DN
Drug	Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A	MCOLN1 CRIP1 THBS1 ASPH FHL1 GAREM1 VCPIP1	4.77e-05	198	109	7	3419_UP
Drug	aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A	THSD7A ZNF473 REST RNF114 MCOLN1 KCNA5 FHL1	4.77e-05	198	109	7	1145_UP
Drug	Bromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ZNF473 ADAM20 ZNF174 LMO3 THBS1 PCNX1 ALB	4.77e-05	198	109	7	7457_UP
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; HL60; HT_HG-U133A	THSD7A ADAMTS1 UBR4 SHB FHL1 NOTCH1 BAHCC1	4.77e-05	198	109	7	2960_UP
Drug	Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; HL60; HT_HG-U133A	ZNF174 CREBBP THBS1 ASPH PCNX1 FHL1 RIMS2	5.08e-05	200	109	7	2534_UP
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	1.23e-05	2	104	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	1.23e-05	2	104	2	cv:C4551859
Disease	Menke-Hennekam syndrome	CREBBP EP300	1.23e-05	2	104	2	cv:C5681632
Disease	Luo-Schoch-Yamamoto syndrome (implicated_via_orthology)	RING1 RNF2	1.23e-05	2	104	2	DOID:0070416 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	1.23e-05	2	104	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	1.23e-05	2	104	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	1.23e-05	2	104	2	C4551859
Disease	urinary tract obstruction (implicated_via_orthology)	BNC2 ADAMTS1	1.23e-05	2	104	2	DOID:5200 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	1.23e-05	2	104	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	1.23e-05	2	104	2	C0035934
Disease	Adenoid Cystic Carcinoma	NSD1 CREBBP MGA EP300 NOTCH1	2.85e-05	100	104	5	C0010606
Disease	cholangiocarcinoma (is_implicated_in)	THBS1 ASPH ALB	6.24e-05	22	104	3	DOID:4947 (is_implicated_in)
Disease	Drug-Induced Stevens Johnson Syndrome	PARP1 ALB EP300	1.45e-04	29	104	3	C1274933
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	PARP1 ALB EP300	1.45e-04	29	104	3	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	PARP1 ALB EP300	1.45e-04	29	104	3	C3658302
Disease	Toxic Epidermal Necrolysis	PARP1 ALB EP300	1.45e-04	29	104	3	C0014518
Disease	Stevens-Johnson Syndrome	PARP1 ALB EP300	1.61e-04	30	104	3	C0038325
Disease	transient cerebral ischemia (biomarker_via_orthology)	ADAMTS1 PARP1 LTBP1 EP300 NOTCH1	2.41e-04	157	104	5	DOID:224 (biomarker_via_orthology)
Disease	Stage IV Skin Melanoma	ADAM7 ADAM29	2.55e-04	7	104	2	C1321872
Disease	Malignant neoplasm of breast	VWF ADAMTS1 UBR4 MCOLN1 ZNF404 PARP1 THBS1 KCNA5 GLI1 NLRC5 EP300 NOTCH1	4.05e-04	1074	104	12	C0006142
Disease	type 2 diabetes mellitus (implicated_via_orthology)	ADAMTS8 PARP1 ADAMTS9 LNPEP	5.30e-04	105	104	4	DOID:9352 (implicated_via_orthology)
Disease	Congenital Abnormality	SALL1 NOTCH1	6.63e-04	11	104	2	C0000768
Disease	brain measurement, neuroimaging measurement	SKIDA1 LMO3 ADAMTS8 THBS1 KCNA5 ADAMTS9 DGKI BAHCC1	7.46e-04	550	104	8	EFO_0004346, EFO_0004464
Disease	Small cell carcinoma of lung	CREBBP RIMS2 EP300	9.26e-04	54	104	3	C0149925
Disease	Diffuse Large B-Cell Lymphoma	CREBBP GLI1 EP300	9.77e-04	55	104	3	C0079744
Disease	femoral neck bone geometry	NSD1 KCNA5	1.09e-03	14	104	2	EFO_0004511
Disease	Alopecia, Male Pattern	TNFRSF10A PARP1	1.25e-03	15	104	2	C4083212
Disease	Hepatitis	PARP1 ALB	1.25e-03	15	104	2	C0019158
Disease	Androgenetic Alopecia	TNFRSF10A PARP1	1.25e-03	15	104	2	C0162311
Disease	hepcidin:transferrin saturation ratio	EML6 PAN3	1.25e-03	15	104	2	EFO_0007902
Disease	Female pattern alopecia (disorder)	TNFRSF10A PARP1	1.25e-03	15	104	2	C0263477
Disease	cortical surface area measurement, neuroimaging measurement	SKIDA1 THBS1 KCNA5 ADAMTS9 DGKI	1.28e-03	227	104	5	EFO_0004346, EFO_0010736
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	CREBBP PRDM14 EP300	1.32e-03	61	104	3	C1961102
Disease	pancreatic ductal carcinoma (is_marker_for)	THBS1 RNF2 ALB	1.32e-03	61	104	3	DOID:3587 (is_marker_for)
Disease	Diabetic Angiopathies	THBS1 ALB	1.43e-03	16	104	2	C0011875
Disease	Microangiopathy, Diabetic	THBS1 ALB	1.43e-03	16	104	2	C0025945
Disease	T-Cell Lymphoma	MGA EP300	1.43e-03	16	104	2	C0079772
Disease	cholangiocarcinoma (is_marker_for)	THBS1 ALB NOTCH1	1.52e-03	64	104	3	DOID:4947 (is_marker_for)
Disease	Bladder Neoplasm	CREBBP GLI1 EP300 NOTCH1	1.55e-03	140	104	4	C0005695
Disease	Malignant neoplasm of urinary bladder	CREBBP GLI1 EP300 NOTCH1	1.59e-03	141	104	4	C0005684
Disease	heart disease (biomarker_via_orthology)	THBS1 EP300	1.62e-03	17	104	2	DOID:114 (biomarker_via_orthology)
Disease	food allergy measurement, parental genotype effect measurement	RNASE9 EML6	1.81e-03	18	104	2	EFO_0005939, EFO_0007016
Disease	Pseudopelade	TNFRSF10A PARP1	2.02e-03	19	104	2	C0086873
Disease	Alopecia	TNFRSF10A PARP1	2.02e-03	19	104	2	C0002170
Disease	Nephritis, Tubulointerstitial	THBS1 ALB	2.47e-03	21	104	2	C0041349
Disease	myocardial infarction (biomarker_via_orthology)	VWF ADAMTS1 THBS1 SLPI	2.51e-03	160	104	4	DOID:5844 (biomarker_via_orthology)
Disease	Renal glomerular disease	CREBBP SALL1	2.97e-03	23	104	2	C0268731
Disease	Glomerulopathy Assessment	CREBBP SALL1	2.97e-03	23	104	2	C4521256
Disease	idiopathic pulmonary fibrosis (is_marker_for)	PARP1 EP300	2.97e-03	23	104	2	DOID:0050156 (is_marker_for)
Disease	Nephritis, Interstitial	THBS1 ALB	3.23e-03	24	104	2	C0027707
Disease	acute myeloid leukemia (is_implicated_in)	NSD1 PHF6 CREBBP	3.30e-03	84	104	3	DOID:9119 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CREGSVIGKCCPSRK	nan	111	Q6ZS92
CKFLPSGKVCRKEVN	ADAM29	446	Q9UKF5
QHTKGCKRKTNGGCP	EP300	1766	Q09472
KAQCKKSSCQGGLAP	BAHCC1	1556	Q9P281
SRNLGKVGSKCCKHP	ALB	451	P02768
PGKINLRTCDQCKHG	BNC2	126	Q6ZN30
DPCQKGTLGCAKKSR	ALPK2	1671	Q86TB3
GTVCGPEKICIRKKC	ADAM20	611	O43506
CQIKKAGSICRPAKD	ADAM7	451	Q9H2U9
DSPRKLDKCGVCGGK	ADAMTS8	671	Q9UP79
FVCDNCLKKTGRPRK	CREBBP	1306	Q92793
KKRASKETADCPGHG	DUS1L	416	Q6P1R4
KKCAGQHRSLGPKDS	ARAP2	721	Q8WZ64
PKEGCKIRCANETKT	ASPH	696	Q12797
NPSCRGQKIKACKTD	CYTH4	326	Q9UIA0
RISPKDRCKSCNGRK	DNAJA1	186	P31689
RPCLKCEKCGKTLTS	CRIP1	26	P50238
DAGQLVSCKKPGCPK	NSD1	2126	Q96L73
GVSPKDRCKLICQAK	ADAMTS1	651	Q9UHI8
SGRASCKKCSESIPK	PARP1	16	P09874
SPCDKFRAKGRKPCK	MCOLN1	51	Q9GZU1
DGCKSGINCPIQKDK	NPC2	91	P61916
GKSSKTKPFRCKPCQ	REST	151	Q13127
GRRCESVINGCKGKP	NOTCH1	1301	P46531
PRVSRQKCVCGKKVA	NFXL1	336	Q6ZNB6
PLTRKCVGASQECKK	MGA	2181	Q8IWI9
PKAGTKSGRKKECCA	PCNX1	421	Q96RV3
KSGRKKECCAGPEEK	PCNX1	426	Q96RV3
LCVCKPGTKGKACET	LTBP1	206	Q14766
SCLKSPCNHLRGKKN	CSNKA2IP	481	A0A1B0GTH6
NEECKSPKKGRCSGH	GAREM1	351	Q9H706
PDTKPKGCAGCNRKI	LMO3	6	Q8TAP4
LPRCTFTKEGCHKKN	LNPEP	131	Q9UIQ6
TGEKPHKCTFEGCRK	GLI1	296	P08151
GLKPSCAKEVKSCKG	ENPP1	96	P22413
PQEKKGCKCGRATQN	MSL2	456	Q9HCI7
RVDGSKCKCSRKGPK	CXCL14	31	O95715
DQKGCPRKKPFECGS	PEG3	406	Q9GZU2
SCGSSPRRKQCKKQQ	NLRC5	126	Q86WI3
KKPGNRECNHLCKSK	HFM1	1136	A2PYH4
ATVAKGVCGACKKPI	PXN	351	P49023
QKGDAPTCGICHKTK	RIMS2	116	Q9UQ26
RKAKNPIGCLADRCK	PAN3	251	Q58A45
CAGCKNPITGKRTVS	FHL1	221	Q13642
KNGASIGCVAPRCKR	G2E3	86	Q7L622
RQARKSACKCPRKGP	LINC00482	186	Q8N8I6
SKPCQGERKRKLVCT	ADAMTS9	891	Q9P2N4
ARRGSCPLEKCNVKA	KCNA5	576	P22460
KKPGCRGLRITTDAC	GPHB5	46	Q86YW7
KGKFKEICERPNGSC	DEFB108A	21	A8MXU0
RCLGKCQKNSPGARK	DBF4B	31	Q8NFT6
RRRQEGKCKQCGKGF	DGKI	256	O75912
VKVSRKNIQGCSCKG	KIF4A	1076	O95239
RKTRTPKCKVPGCFL	GCNA	486	Q96QF7
VRKLKKGGRCCAFSP	EML6	1036	Q6ZMW3
GTGRCRKSCKEIERK	DEFB115	41	Q30KQ5
LKEKVICRACGTGNP	DZANK1	286	Q9NVP4
CKICGRAFTTKGNLK	SALL1	736	Q9NSC2
ALRSGNKECPTCRKK	RING1	76	Q06587
RSGNKECPTCRKKLV	RNF2	81	Q99496
RKKVCTKCGIEASPG	RPH3AL	116	Q9UNE2
TTGPDCGKCKKNFRT	NTNG2	311	Q96CW9
CKEDSGCTPGKAKRK	P2RX1	126	P51575
SPTACGGKKLLNKCA	SHB	211	Q15464
DKGDRKFPCSLCKRS	PRDM14	426	Q9GZV8
KAGVCPPKKSAQCLR	SLPI	31	P03973
RCSKSCGSGVKVRSK	THSD7A	1046	Q9UPZ6
CKRKRGGAKDCLLAP	SKIDA1	271	Q1XH10
VPCKNGIRKCNRSKG	RNASE9	121	P60153
KPESCVPCGKRIKFG	RACGAP1	296	Q9H0H5
TVRCPSCCGAKRKAK	SSUH2	196	Q9Y2M2
VSLCCKATGKPRPDK	CILP	326	O75339
PSEGEVCCKKRKPGQ	SHANK2-AS3	81	Q9BTD1
RQRKGAAPAEKKCGA	PREB	116	Q9HCU5
IHSSEKPNRCKECGK	ZNF30	141	P17039
RIHTGEKPLKCKQCG	ZNF30	196	P17039
THTGDGPQKCKICGK	ZNF823	381	P16415
HTGEKPNACKVCGKT	ZNF440	166	Q8IYI8
EQKKGPTRQRKCGFC	PHF6	6	Q8IWS0
GKPCEGEARETKACK	THBS1	471	P07996
KPHKCKECGKGFIQR	ZNF197	396	O14709
HRGEKPNECKECGKT	ZNF334	371	Q9HCZ1
AKGAKPCAVSAGRSK	ZNF174	226	Q15697
NKGCSHPSVKCKKRV	VWF	911	P04275
KQCLIKKSGGAPECA	MUC13	376	Q9H3R2
CLKPKKPVCGVCRSA	RNF114	56	Q9Y508
GTSKRLKVDGQKNCC	TUT1	656	Q9H6E5
AKKGCLARVQKLCTP	TNKS	811	O95271
KSCERQKAKEGNGCR	ZNF274	471	Q96GC6
HSGIKPFQCDRCGKK	ZBTB44	421	Q8NCP5
CVTCQDKGSRKVSGP	TSTD2	456	Q5T7W7
KCTGKDGHLNKPICI	VCPIP1	331	Q96JH7
KCSRGCPRGMVKVKD	TNFRSF10A	206	O00220
SGQKKKPVGIHVCCF	TAS1R2	501	Q8TE23
CGGLVRTDKKPALCK	USP20	176	Q9Y2K6
IHTGVKPQKCKECGK	ZNF404	516	Q494X3
KGRRKRKGSFPCPEC	TRIM17	51	Q9Y577
KCKQCGKGFSRRSAL	ZNF226	336	Q9NYT6
TKGALNKSRCTICGK	ZMYM2	416	Q9UBW7
LTHSGKKPCVSKQCG	ZNF705B	136	P0CI00
KKPCVSKQCGKSLRN	ZNF705B	141	P0CI00
LTHSGKKPCVSKQCG	ZNF705D	136	P0CH99
KKPCVSKQCGKSLRN	ZNF705D	141	P0CH99
RHTGKNPFKCKECGK	ZNF708	161	P17019
LAAEKPHSCGQCGKR	ZNF213	311	O14771
TGERPHKCKICGKAF	ZNF491	266	Q8N8L2
PDGCKQCGKAFRSAK	ZNF491	326	Q8N8L2
RHTGKNPCKFTECGK	ZNF66	166	Q6ZN08
FTRKEGLSKCGRCKQ	SMYD2	56	Q9NRG4
EKPKKSSLCRTVEGC	UBR4	1781	Q5T4S7
CPECGKGFLQKRSLK	ZNF425	696	Q6IV72
DTSGKLRIHKCKGPS	SULF1	466	Q8IWU6
CKLSHGKTEVGRKLP	WDR7	856	Q9Y4E6
RSHKCGTGEKSLKCP	ZNF605	91	Q86T29
CGGLARTDKKPAICK	USP33	216	Q8TEY7
SSECEKPKINGKVCG	ZBBX	121	A8MT70
PCVECGKGFKRKTAL	ZNF785	341	A8K8V0
HARKKPLVCNECGKT	ZNF473	696	Q8WTR7
RHTGKKPFKCIECGK	ZNF737	166	O75373
LDGKLACVNKCTKGT	MUC12	5321	Q9UKN1