Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneuron development

RPGRIP1 FAT4 STRN AHI1 PTPRG MAP1B HS6ST1 PTPRQ LAMA1 RAPGEF4 LAMA3 CDH23 KIAA1755 PRKCA BCAN TECTA PLXNB1 CASK

1.38e-0514638218GO:0048666
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

SLC12A6 SLC12A4 MAP1B DTNA NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

7.36e-059318213GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

SLC12A6 SLC12A4 MAP1B DTNA NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

7.36e-059318213GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

SLC12A6 SLC12A4 MAP1B DTNA NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

8.03e-059398213GO:0099537
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A6 SLC12A4

9.32e-054822GO:0140157
GeneOntologyBiologicalProcessdesmosome assembly

JUP PRKCA

9.32e-054822GO:0002159
GeneOntologyBiologicalProcesssynaptic signaling

SLC12A6 SLC12A4 MAP1B DTNA NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

1.18e-049768213GO:0099536
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

PRKCA UNC13C GIT2 SNCA CASK

1.42e-04125825GO:0016079
GeneOntologyBiologicalProcessneuron projection development

FAT4 STRN AHI1 PTPRG MAP1B LAMA1 RAPGEF4 LAMA3 CDH23 KIAA1755 PRKCA BCAN TECTA PLXNB1 CASK

1.46e-0412858215GO:0031175
GeneOntologyBiologicalProcessregulated exocytosis

RAPGEF4 PRKCA UNC13C GIT2 SNCA GAB2 CASK

1.59e-04291827GO:0045055
GeneOntologyBiologicalProcessinner ear receptor cell development

FAT4 PTPRQ CDH23 TECTA

2.05e-0473824GO:0060119
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

FAT4 AHI1 LAMA1 CTNND1

2.05e-0473824GO:0001738
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

MAP1B NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

2.93e-046638210GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

MAP1B NISCH PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA GRM6 CASK

2.96e-046648210GO:0099177
GeneOntologyBiologicalProcesspositive regulation of transport

JUP ERBB3 AHI1 CD19 RAPGEF4 PRKCA PSMD9 PLCD1 SNCA EDEM1 GRM6 GAB2 CASK

3.22e-0410818213GO:0051050
GeneOntologyBiologicalProcessregulation of exocytosis

RAPGEF4 PRKCA GIT2 SNCA GAB2 CASK

3.33e-04233826GO:0017157
GeneOntologyCellularComponentlaminin-3 complex

LAMA1 LAMA3

4.66e-053832GO:0005608
GeneOntologyCellularComponentcell-cell junction

JUP STRN FAT2 AHI1 DEF6 LAMA1 LAMA3 PRKCA CTNND1 CASK

1.15e-045918310GO:0005911
GeneOntologyCellularComponentapical part of cell

SLC12A6 FAT4 ERBB3 SPEF1 SLC9A3 CDHR2 PTPRQ RAPGEF4 CDH23 PRKCA

1.17e-045928310GO:0045177
GeneOntologyCellularComponentnon-motile cilium

RPGRIP1 AHI1 MAP1B RAPGEF4 CDH23 PRKCA

1.30e-04196836GO:0097730
GeneOntologyCellularComponentaxon terminus

PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA

1.90e-04210836GO:0043679
GeneOntologyCellularComponentsuper elongation complex

AFF2 AFF3

2.31e-046832GO:0032783
GeneOntologyCellularComponentphotoreceptor cell cilium

RPGRIP1 AHI1 MAP1B RAPGEF4 PRKCA

2.32e-04139835GO:0097733
GeneOntologyCellularComponentcatenin complex

JUP CDH23 CTNND1

2.75e-0432833GO:0016342
GeneOntologyCellularComponentphotoreceptor distal connecting cilium

RPGRIP1 AHI1

3.23e-047832GO:0120206
GeneOntologyCellularComponentneuron projection terminus

PENK RAPGEF4 PRKCA UNC13C GIT2 SNCA

3.32e-04233836GO:0044306
GeneOntologyCellularComponentdistal axon

MAP1B PENK RAPGEF4 PRKCA UNC13C GIT2 CTNND1 SNCA

3.33e-04435838GO:0150034
GeneOntologyCellularComponent9+0 non-motile cilium

RPGRIP1 AHI1 MAP1B RAPGEF4 PRKCA

3.61e-04153835GO:0097731
GeneOntologyCellularComponentcalyx of Held

PRKCA UNC13C GIT2

3.92e-0436833GO:0044305
GeneOntologyCellularComponentzonula adherens

JUP CTNND1

4.29e-048832GO:0005915
GeneOntologyCellularComponentanchoring junction

JUP STRN FAT2 AHI1 CDHR2 DEF6 LAMA1 LAMA3 PRKCA GIT2 CTNND1 CASK

4.56e-049768312GO:0070161
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMA3

6.87e-0410832GO:0043256
GeneOntologyCellularComponentaxon

SLC12A6 MAP1B DTNA PENK RAPGEF4 PRKCA UNC13C BCAN GIT2 CTNND1 SNCA

7.75e-048918311GO:0030424
GeneOntologyCellularComponenthemidesmosome

JUP LAMA3

8.37e-0411832GO:0030056
GeneOntologyCellularComponentphotoreceptor outer segment

AHI1 MAP1B RAPGEF4 PRKCA

1.00e-03111834GO:0001750
GeneOntologyCellularComponentadherens junction

JUP FAT2 AHI1 LAMA3 CTNND1

1.57e-03212835GO:0005912
GeneOntologyCellularComponentcluster of actin-based cell projections

SLC9A3 CDHR2 PTPRQ RAPGEF4 CDH23

1.95e-03223835GO:0098862
GeneOntologyCellularComponentdendrite

PCSK5 STRN MAP1B PENK RAPGEF4 PRKCA BCAN CTNND1 GRM6 CASK

2.08e-038588310GO:0030425
GeneOntologyCellularComponentdendritic tree

PCSK5 STRN MAP1B PENK RAPGEF4 PRKCA BCAN CTNND1 GRM6 CASK

2.12e-038608310GO:0097447
GeneOntologyCellularComponentextrinsic component of plasma membrane

JUP DTNA CDH23 CTNND1

2.17e-03137834GO:0019897
GeneOntologyCellularComponentextrinsic component of membrane

JUP DTNA CDH23 KIAA1755 CTNND1

2.23e-03230835GO:0019898
GeneOntologyCellularComponentbasal plasma membrane

SLC12A6 ERBB3 SPEF1 PTPRQ RAPGEF4 CASK

2.86e-03354836GO:0009925
GeneOntologyCellularComponentapical plasma membrane

SLC12A6 ERBB3 SPEF1 SLC9A3 CDHR2 PTPRQ RAPGEF4

3.23e-03487837GO:0016324
GeneOntologyCellularComponentsomatodendritic compartment

PCSK5 STRN MAP1B PENK RAPGEF4 PRKCA TMPRSS5 BCAN CTNND1 SNCA GRM6 CASK

3.24e-0312288312GO:0036477
GeneOntologyCellularComponentsite of polarized growth

MAP1B RAPGEF4 CTNND1 SNCA GRM6

3.37e-03253835GO:0030427
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13C CTNND1

3.73e-0323832GO:0098831
GeneOntologyCellularComponentbasal part of cell

SLC12A6 ERBB3 SPEF1 PTPRQ RAPGEF4 CASK

3.94e-03378836GO:0045178
GeneOntologyCellularComponentactin-based cell projection

SPEF1 CDHR2 PTPRQ DEF6 CDH23

5.01e-03278835GO:0098858
GeneOntologyCellularComponentapicolateral plasma membrane

JUP CTNND1

5.51e-0328832GO:0016327
GeneOntologyCellularComponentneuronal cell body

PCSK5 STRN MAP1B PENK RAPGEF4 PRKCA TMPRSS5 SNCA CASK

5.81e-03835839GO:0043025
DomainKCC1

SLC12A6 SLC12A4

1.72e-052782IPR000622
DomainLAM_G_DOMAIN

FAT4 FAT2 LAMA1 LAMA3

1.87e-0538784PS50025
DomainLaminin_G_2

FAT4 FAT2 LAMA1 LAMA3

2.29e-0540784PF02210
DomainLamG

FAT4 FAT2 LAMA1 LAMA3

3.37e-0544784SM00282
DomainEGF

PCSK5 FAT4 FAT2 LAMA1 LAMA3 BCAN TECTA

5.65e-05235787SM00181
DomainEGF-like_dom

PCSK5 FAT4 FAT2 LAMA1 LAMA3 BCAN TECTA

8.12e-05249787IPR000742
DomainLaminin_G

FAT4 FAT2 LAMA1 LAMA3

1.01e-0458784IPR001791
DomainTF_AF4/FMR2

AFF2 AFF3

1.03e-044782IPR007797
DomainKCL_cotranspt

SLC12A6 SLC12A4

1.03e-044782IPR000076
DomainAF-4

AFF2 AFF3

1.03e-044782PF05110
DomainLaminin_aI

LAMA1 LAMA3

1.71e-045782IPR009254
DomainLaminin_I

LAMA1 LAMA3

1.71e-045782PF06008
DomainLaminin_II

LAMA1 LAMA3

1.71e-045782PF06009
DomainLaminin_domII

LAMA1 LAMA3

1.71e-045782IPR010307
DomainGF_recep_IV

PCSK5 ERBB3

2.55e-046782PF14843
DomainGF_recep_IV

PCSK5 ERBB3

2.55e-046782IPR032778
DomainSLC12A_fam

SLC12A6 SLC12A4

3.57e-047782IPR004842
DomainSLC12_C

SLC12A6 SLC12A4

4.74e-048782IPR018491
DomainLAMININ_IVA

LAMA1 LAMA3

4.74e-048782PS51115
DomainLaminin_B

LAMA1 LAMA3

4.74e-048782PF00052
DomainSLC12

SLC12A6 SLC12A4

4.74e-048782PF03522
DomainLamB

LAMA1 LAMA3

4.74e-048782SM00281
DomainLaminin_IV

LAMA1 LAMA3

4.74e-048782IPR000034
DomainGrowth_fac_rcpt_

PCSK5 FAT4 ERBB3 LAMA1 LAMA3

4.93e-04156785IPR009030
Domain-

FAT4 FAT2 LAMA1 LAMA3

6.72e-04957842.60.120.200
DomainCadherin_CS

FAT4 FAT2 CDHR2 CDH23

1.12e-03109784IPR020894
DomainCADHERIN_1

FAT4 FAT2 CDHR2 CDH23

1.28e-03113784PS00232
DomainCadherin

FAT4 FAT2 CDHR2 CDH23

1.28e-03113784PF00028
DomainCADHERIN_2

FAT4 FAT2 CDHR2 CDH23

1.33e-03114784PS50268
Domain-

FAT4 FAT2 CDHR2 CDH23

1.33e-031147842.60.40.60
DomainCA

FAT4 FAT2 CDHR2 CDH23

1.37e-03115784SM00112
DomainCadherin-like

FAT4 FAT2 CDHR2 CDH23

1.41e-03116784IPR015919
DomainCadherin

FAT4 FAT2 CDHR2 CDH23

1.51e-03118784IPR002126
DomainLaminin_N

LAMA1 LAMA3

1.99e-0316782IPR008211
DomainLAMININ_NTER

LAMA1 LAMA3

1.99e-0316782PS51117
DomainLaminin_N

LAMA1 LAMA3

1.99e-0316782PF00055
DomainLamNT

LAMA1 LAMA3

1.99e-0316782SM00136
DomainC2

RPGRIP1 PRKCA UNC13C PLCD1

2.21e-03131784PF00168
DomainConA-like_dom

FAT4 TRIM69 FAT2 LAMA1 LAMA3

2.23e-03219785IPR013320
DomainFurin_repeat

PCSK5 ERBB3

2.52e-0318782IPR006212
DomainFU

PCSK5 ERBB3

2.52e-0318782SM00261
DomainC2

RPGRIP1 PRKCA UNC13C PLCD1

2.60e-03137784SM00239
DomainC2

RPGRIP1 PRKCA UNC13C PLCD1

2.96e-03142784PS50004
Domain-

RPGRIP1 PRKCA UNC13C PLCD1

3.43e-031487842.60.40.150
DomainAA-permease/SLC12A_dom

SLC12A6 SLC12A4

3.77e-0322782IPR004841
DomainAA_permease

SLC12A6 SLC12A4

3.77e-0322782PF00324
DomainEGF_1

FAT4 FAT2 LAMA1 LAMA3 BCAN

4.28e-03255785PS00022
DomainEGF-like_CS

FAT4 FAT2 LAMA1 LAMA3 BCAN

4.72e-03261785IPR013032
DomainC2_dom

RPGRIP1 PRKCA UNC13C PLCD1

4.94e-03164784IPR000008
DomainEGF_2

FAT4 FAT2 LAMA1 LAMA3 BCAN

5.04e-03265785PS01186
DomainEGF_LAM_2

LAMA1 LAMA3

6.94e-0330782PS50027
DomainEGF_LAM_1

LAMA1 LAMA3

6.94e-0330782PS01248
DomainGalactose-bd-like

PCSK5 AEBP1 LAMA1

7.15e-0394783IPR008979
DomainArm

JUP CTNND1

7.40e-0331782PF00514
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

ERBB3 LAMA1 LAMA3 PRKCA

5.46e-0546644M239
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA1 LAMA3 PRKCA CASK

1.46e-0459644M27218
PathwayBIOCARTA_PLCD_PATHWAY

PRKCA PLCD1

2.01e-045642MM1587
PathwayBIOCARTA_PLCD_PATHWAY

PRKCA PLCD1

2.01e-045642M22080
PathwayBIOCARTA_AGR_PATHWAY

LAMA1 LAMA3 GIT2

3.66e-0431643MM1343
PathwayPID_SYNDECAN_4_PATHWAY

LAMA1 LAMA3 PRKCA

4.03e-0432643M165
PathwayREACTOME_REGULATION_OF_CDH19_EXPRESSION_AND_FUNCTION

JUP CTNND1

4.20e-047642M48017
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A4

4.20e-047642M27339
PathwayREACTOME_CDH11_HOMOTYPIC_AND_HETEROTYPIC_INTERACTIONS

JUP CTNND1

4.20e-047642M48038
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A4

4.20e-047642MM15081
PathwayPID_SYNDECAN_2_PATHWAY

LAMA1 LAMA3 CASK

4.42e-0433643M240
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA1 LAMA3 PRKCA

4.42e-0433643M39503
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

STRN ERBB3 CD19 GAB2

5.43e-0483644M27163
PathwayREACTOME_REGULATION_OF_CDH11_FUNCTION

JUP CTNND1

5.58e-048642MM17072
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

PCSK5 JUP ERBB3 LAMA1 LAMA3 PRKCA CTNND1 GAB2 DNMT1

6.28e-04532649M27870
Pubmed

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).

JUP PTPRQ CTNND1

2.84e-061283316973135
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A6 SLC12A4

5.63e-06283234031912
Pubmed

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo.

PRKCA PLCD1

5.63e-06283229030553
Pubmed

Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments.

MAP1B SNCA

5.63e-06283210764738
Pubmed

Associations of ChREBP and Global DNA Methylation with Genetic and Environmental Factors in Chinese Healthy Adults.

MLXIPL DNMT1

5.63e-06283227281235
Pubmed

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

SLC12A6 SLC12A4

5.63e-06283231835175
Pubmed

The mouse Laf4 gene: exon/intron organization, cDNA sequence, alternative splicing, and expression during central nervous system development.

AFF2 AFF3

5.63e-06283212079280
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A6 SLC12A4

5.63e-06283217510708
Pubmed

Control of GM-CSF-Dependent Dendritic Cell Differentiation and Maturation by DEF6 and SWAP-70.

SWAP70 DEF6

5.63e-06283232709659
Pubmed

SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.

SWAP70 DEF6

5.63e-06283227561029
Pubmed

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases.

SNCA DNMT1

5.63e-06283221296890
Pubmed

Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo.

SLC9A3 PRKCA

5.63e-06283217016558
Pubmed

Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment.

LAMA1 LAMA3

5.63e-0628328601594
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RPGRIP1 STRN AHI1 PTPRG NISCH CLPTM1 PTPRQ CDH23 PSMD9 GIT2 GGA1 GAB2 DYNC1LI2

1.44e-051321831327173435
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

AHI1 MAP1B GIT2 CTNND1 GAB2

1.67e-0513283516944949
Pubmed

Mammalian Auditory Hair Cell Bundle Stiffness Affects Frequency Tuning by Increasing Coupling along the Length of the Cochlea.

CDH23 TECTA

1.69e-05383229874579
Pubmed

Def-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiation.

SWAP70 DEF6

1.69e-05383217403664
Pubmed

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

CD19 DNMT1

1.69e-05383219801979
Pubmed

Interleukin-13 Receptor α1-Mediated Signaling Regulates Age-Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis.

SWAP70 DEF6

1.69e-05383235438841
Pubmed

Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus.

MAP1B SNCA

1.69e-05383231235589
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A6 SLC12A4

1.69e-05383211551954
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A6 SLC12A4

1.69e-05383215262997
Pubmed

IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus.

SWAP70 DEF6

1.69e-05383226544714
Pubmed

PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.

PRKCA CTNND1

1.69e-05383218950621
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A6 SLC12A4

1.69e-05383221733850
Pubmed

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

SLC12A6 SLC12A4

1.69e-05383231352162
Pubmed

Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease.

PRKCA DNMT1

1.69e-05383234482802
Pubmed

Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.

SLC12A6 SLC12A4

1.69e-05383235274823
Pubmed

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

AFF2 AFF3

1.69e-05383221330300
Pubmed

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin.

PRKCA CTNND1

1.69e-05383229216867
Pubmed

PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity.

PRKCA CTNND1

1.69e-05383222798526
Pubmed

Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.

NUTM1 MAML2

1.69e-05383231145701
Pubmed

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.

JUP PRKCA CTNND1

1.69e-052183315775979
Pubmed

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.

JUP ERBB3 PRKCA CTNND1 SNCA

1.80e-0513483524658140
Pubmed

Regulation of systemic autoimmunity and CD11c+ Tbet+ B cells by SWEF proteins.

SWAP70 DEF6

3.37e-05483228780965
Pubmed

AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination.

CD19 AFF3

3.37e-05483236001653
Pubmed

Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes.

JUP CTNND1

3.37e-0548327876318
Pubmed

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation.

PRKCA MMUT

3.37e-05483230913280
Pubmed

Reduced expression of E-cadherin/catenin complex in hepatocellular carcinomas.

JUP CTNND1

3.37e-05483218837082
Pubmed

Dystroglycan protein distribution coincides with basement membranes and muscle differentiation during mouse embryogenesis.

LAMA1 LAMA3

3.37e-05483217676646
Pubmed

Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.

SWAP70 DEF6

3.37e-05483222370718
Pubmed

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

MAP1B SNCA

3.37e-05483231277379
Pubmed

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.

AFF2 AFF3

3.37e-05483211923441
Pubmed

Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-α activation and disruption of the p120-vascular endothelial cadherin interaction.

PRKCA CTNND1

3.37e-05483223887639
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A6 SLC12A4

3.37e-05483212637262
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KLHL29 SLC12A6 GALNT10 PTPRG MAP1B DTNA AFF3 LAMA3 TMPRSS5 TANGO2 CTNND1 TECTA CASK

4.99e-051489831328611215
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

MAGEA2 RPGRIP1 JUP SWAP70 RAPGEF4 DTX2 CASK

5.11e-0540283724722188
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA1 LAMA3

5.60e-05583211969289
Pubmed

N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.

JUP CTNND1

5.60e-05583212604612
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA1 LAMA3

5.60e-0558329415429
Pubmed

Expression and interaction of different catenins in colorectal carcinoma cells.

JUP CTNND1

5.60e-05583211712088
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA1 LAMA3

5.60e-0558329389447
Pubmed

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.

JUP CTNND1

5.60e-0558327542250
Pubmed

The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin.

JUP CTNND1

5.60e-0558327651399
Pubmed

miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer.

ERBB3 DNMT1

5.60e-05583227906180
Pubmed

Regulation of the ErbB3 binding protein Ebp1 by protein kinase C.

ERBB3 PRKCA

5.60e-05583211325528
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA1 LAMA3

5.60e-05583211829758
Pubmed

Testing gene function early in the B cell lineage in mb1-cre mice.

CD19 DNMT1

5.60e-05583216940357
Pubmed

Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein.

JUP ERBB3

5.60e-05583212939402
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

AMER2 SLC12A4 PTPRG DTNA CTNND1 CDCP1 PLXNB1 CASK

6.57e-0556983830639242
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA1 LAMA3

8.39e-0568329597096
Pubmed

Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes.

CTNND1 CASK

8.39e-05683212151522
Pubmed

The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.

SWAP70 DEF6

8.39e-05683228811467
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMA1 LAMA3

8.39e-0568329506922
Pubmed

Regulation of age-associated B cells by IRF5 in systemic autoimmunity.

SWAP70 DEF6

8.39e-05683229483597
Pubmed

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex.

JUP CTNND1

8.39e-05683211226248
Pubmed

Functional proteomics mapping of a human signaling pathway.

JUP TRIM69 STRN SLC12A4 SMARCE1 QRICH1 GGA1 CASK

8.55e-0559183815231748
Pubmed

The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.

AHI1 PENK BCAN SNCA

9.18e-059883419554387
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

FAT4 AFF2 ANGEL1 CTNND1 GGA1 GAB2 DYNC1LI2 DNMT1 CASK

9.96e-0577783935844135
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT2

1.17e-04783216059920
Pubmed

The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn).

JUP CTNND1

1.17e-04783212370829
Pubmed

Gamma-secretase-dependent and -independent effects of presenilin1 on beta-catenin.Tcf-4 transcriptional activity.

JUP CTNND1

1.17e-04783219114997
Pubmed

Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice.

SWAP70 DEF6

1.17e-04783234376664
Pubmed

O-glycosylation modulates integrin and FGF signalling by influencing the secretion of basement membrane components.

GALNT10 LAMA1 EDEM1

1.21e-044083322643896
Pubmed

Mouse model resources for vision research.

RPGRIP1 LAMA1 GRM6

1.31e-044183321052544
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GALNT10 JUP FAT4 MAP1B LOX CLPTM1 LAMA1 SMARCE1 EDEM1 PLXNB1 DNMT1

1.32e-041201831135696571
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

CDH23 TECTA

1.56e-04883221165971
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA1 LAMA3

1.56e-0488329489770
Pubmed

The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton.

JUP CTNND1

1.56e-0488329535896
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A6 SLC12A4

1.56e-04883221613606
Pubmed

Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.

PRKCA UNC13C

1.56e-04883227376238
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA1 LAMA3

1.56e-0488328872465
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A6 SLC12A4

1.56e-04883211395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A6 SLC12A4

1.56e-04883224393035
Pubmed

Tubulin seeds alpha-synuclein fibril formation.

MAP1B SNCA

1.56e-04883211698390
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA1 LAMA3

1.56e-0488329852162
Pubmed

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

SLC12A6 SLC12A4

1.56e-04883212386165
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PCSK5 ERBB3 MAP1B NISCH ANGEL1 EDEM1 PLXNB1 DNMT1

1.64e-0465083838777146
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

AMER2 MAP1B PRKCA BCAN CTNND1 DYNC1LI2

1.87e-0434783617114649
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

JUP MAP1B RIC8A API5 SNCA DYNC1LI2 CASK

1.92e-0449883736634849
Pubmed

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

MAGEA2 NUTM1 RPGRIP1 JUP TRIM69 DEF6 SMARCE1 PSMD9 QRICH1 DTX2 ZNF496 GAB2

1.96e-041477831231515488
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

ERBB3 DNAH9 DYNC1LI2

1.97e-04478338812413
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A6 SLC12A4

2.00e-04983219323993
Pubmed

Nucleotide exchange factor RIC-8 is indispensable in mammalian early development.

LAMA1 RIC8A

2.00e-04983221069829
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PKMYT1 SLC12A6 JUP SLC12A4 NISCH ANGEL1 CTNND1

2.07e-0450483734432599
Pubmed

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing.

SMARCE1 DNMT1

2.50e-041083215696166
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA1 LAMA3

2.50e-04108329034910
Pubmed

Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.

RPGRIP1 AHI1

2.50e-041083220592197
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

JUP BRD8 AHI1 ANGEL1 DTX2 TANGO2 CDCP1 ZNF496 PLXNB1 DYNC1LI2

2.57e-041084831011544199
Pubmed

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.

CTU2 ZNF460 NISCH SMARCE1 RIC8A API5 CTNND1 DYNC1LI2

2.81e-0470483832994395
InteractionPTPRQ interactions

JUP AHI1 PTPRQ CTNND1

3.17e-0625834int:PTPRQ
InteractionLYN interactions

SLC12A6 JUP ERBB3 SLC12A4 PTPRG CD19 DTNA NISCH CDH23 CTNND1 SNCA GAB2 CASK

7.32e-067208313int:LYN
InteractionRABGAP1L interactions

JUP STRN PSMD9 GIT2 GGA1 CASK

1.18e-05123836int:RABGAP1L
Cytoband3p21.31

QRICH1 CDCP1 PLXNB1

8.12e-041008333p21.31
Cytoband6q23.3

AHI1 IL20RA

1.18e-03288326q23.3
Cytoband5q35.2

CDHR2 SIMC1

1.55e-03328325q35.2
CytobandEnsembl 112 genes in cytogenetic band chr3p21

NISCH QRICH1 CDCP1 PLXNB1

2.64e-03316834chr3p21
GeneFamilyCadherin related

FAT4 FAT2 CDHR2 CDH23

2.52e-071760424
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF2 AFF3

6.47e-0546021145
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF2 AFF3

3.84e-0496021280
GeneFamilyLaminin subunits

LAMA1 LAMA3

7.00e-0412602626
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRG PTPRQ

2.18e-0321602813
CoexpressionPRC2_EED_DN.V1_DN

JUP SLC12A4 SLC2A6 HS6ST1 SURF2 AFF3 PLXNB1

2.72e-06193837M2734
CoexpressionGSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP

PCSK5 GALNT10 STRN AFF2 ZNF460 GIT2 CASK

3.23e-06198837M8335
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP

PCSK5 SLC12A6 AEBP1 AFF3 PRKCA MAML2 ZNF496

3.23e-06198837M3104
ToppCellLA|World / Chamber and Cluster_Paper

KLHL29 PCSK5 MLXIPL GALNT10 MAP1B AFF3 MAML2 GAB2

2.97e-09193838d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

JUP FAT2 PTPRG LOX LAMA3 CTNND1 SNCA

7.83e-081948372932f704656ca368565ec12f3452af3b18e8df12
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL29 FAT2 AFF2 MAP1B DTNA LAMA1 SNCA

8.39e-08196837a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG DTNA PTPRQ LAMA1 TECTA DNAH9

5.54e-07160836c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG DTNA PTPRQ LAMA1 TECTA DNAH9

5.54e-0716083625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 AEBP1 LOX PENK KIAA1755 ZNF496

1.07e-06179836ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

KLHL29 PCSK5 MLXIPL AFF2 DTNA MYOM3

1.46e-061898360be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK5 ERBB3 DTNA PRKCA BCAN PLPPR1

1.86e-06197836bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRG AFF3 PRKCA MAML2 GAB2 CASK

1.92e-061988361996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPEF1 MAP1B AEBP1 DTNA BCAN DNAH9

1.92e-0619883601d563ccdc0da02dac04169e713844fecb4233a1
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK-L1-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK5 FAT4 ERBB3 PENK MAML2 PLPPR1

2.03e-0620083608a00b0687bef5fef12bfa8e52ae4570071bae5e
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK5 FAT4 ERBB3 PENK MAML2 PLPPR1

2.03e-06200836266990ee2e835e98b92dfdf7e3114f9737ffa85e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC9A3 LAMA3 IL20RA UNC13C CDCP1

3.18e-0612183505c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPGRIP1 AFF2 SWAP70 PTPRQ AFF3

1.10e-05156835203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 AFF2 DTNA TMPRSS5 BCAN

1.71e-05171835b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 DEF6 PENK PRKCA PLPPR1

1.76e-05172835b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 SWAP70 AFF3 PRKCA CMAHP

1.76e-05172835910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A6 CD19 SWAP70 DTNA AFF3

1.86e-051748358bdf5a97faf1cf0426d1a8851f8a3e27578f7598
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A6 CD19 SWAP70 DTNA AFF3

1.86e-05174835fbf998dd33ac27dad7639ea85fca393ba2835307
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKMYT1 FAT2 CDHR2 TMPRSS5 PLXNB1

1.86e-05174835207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 PTPRG AEBP1 LOX MAML2

1.91e-051758351799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MLXIPL ERBB3 CDHR2 KIAA1755 PLPPR1

1.96e-051768351e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 MAP1B LOX PTPRQ SNCA

2.02e-051778354d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG MAP1B DTNA AFF3 KIAA1755

2.02e-05177835e65c0568dc5852108e9802273499bc7cf88fafab
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 MYOM3 BCAN CDCP1 PLXNB1

2.07e-0517883576e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 MYOM3 BCAN CDCP1 PLXNB1

2.07e-0517883582f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 MAP1B LOX PTPRQ SNCA

2.07e-05178835edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 MYOM3 BCAN CDCP1 PLXNB1

2.07e-051788355442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

JUP SWAP70 AEBP1 SIMC1 AFF3

2.07e-0517883571ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 MYOM3 BCAN CDCP1 PLXNB1

2.07e-05178835523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD19 SWAP70 AFF3 PRKCA CMAHP

2.19e-05180835c12c1cc206f7e63e5722471bd3eb84caddb84129
ToppCellfacs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL TRIM69 BCAN PLPPR1 PLXNB1

2.19e-05180835c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD19 SWAP70 AFF3 PRKCA CMAHP

2.19e-05180835d8135f73a89b97168f2048258f4648e23536ece4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B LOX PTPRQ SNCA CMAHP

2.19e-05180835d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellfacs-Marrow-B-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL TRIM69 BCAN PLPPR1 PLXNB1

2.19e-0518083507ac979b21be2425294d9818c48b5a1e6f014c19
ToppCelldroplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL29 ERBB3 BCAN CDCP1 PLXNB1

2.25e-05181835cadb18fc73031eb9f779599e15cd7861337fee78
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JUP CD19 SWAP70 AEBP1 AFF3

2.25e-05181835ca34d83daca10c5fa52ecdf4eba7d31b4e7e056e
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL29 ERBB3 BCAN CDCP1 PLXNB1

2.25e-0518183585bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC9A3 MAP1B LOX RAPGEF4 PLXNB1

2.31e-05182835193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT10 ERBB3 BCAN MAML2 PLPPR1

2.31e-051828358a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK5 ERBB3 DTNA PRKCA BCAN

2.31e-05182835ecb5624c9074cc6449fad961df54c926c2681d54
ToppCellremission-B_naive|World / disease stage, cell group and cell class

JUP CD19 SWAP70 AFF3 GRM6

2.31e-05182835cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT10 ERBB3 BCAN MAML2 PLPPR1

2.31e-05182835e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellBasal|World / shred by cell class for mouse tongue

SLC12A4 MAP1B HS6ST1 AFF3 LAMA3

2.37e-05183835c6729a207526ff4aa48176207b9353176f631fea
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL29 MAP1B AEBP1 PENK KIAA1755

2.37e-05183835a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

KLHL29 MAP1B LOX PTPRQ SNCA

2.37e-05183835fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCelldroplet-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL29 MAP1B AEBP1 PENK KIAA1755

2.37e-05183835ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PTPRQ LAMA1 UNC13C DNAH9

2.43e-051848352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PTPRQ LAMA1 UNC13C DNAH9

2.43e-05184835ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PTPRQ LAMA1 UNC13C DNAH9

2.43e-051848352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 AEBP1 PENK KIAA1755 MMUT

2.43e-05184835d754c3de621429b220ae4ac426cdfc619e848462
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT10 ERBB3 BCAN MAML2 PLPPR1

2.49e-051858352e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT10 ERBB3 BCAN MAML2 PLPPR1

2.49e-051858357aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB3 KIAA1755 MAML2 PLPPR1 PLXNB1

2.62e-0518783597e520705491c8f52a32025311a9fa7b9176979a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B LOX PTPRQ SNCA CMAHP

2.69e-051888359db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 MAP1B TMPRSS5 BCAN SNCA

2.69e-05188835ccd2541892112a7a303f766adf9a7afeb754498c
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL MAP1B NISCH RAPGEF4 PRKCA

2.69e-05188835a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B LOX PTPRQ SNCA CMAHP

2.69e-05188835047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 LAMA1 MYOM3 LAMA3 PLPPR1

2.76e-051898355d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB3 LAMA1 KIAA1755 MAML2 PLXNB1

2.83e-051908352de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB3 LAMA1 KIAA1755 MAML2 PLXNB1

2.90e-05191835f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 MAP1B LOX PTPRQ SNCA

2.98e-05192835ef0aba777072429a6ab7dcfcc305673975946580
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL MAP1B NISCH RAPGEF4 PRKCA

2.98e-051928351304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 MAP1B LOX PTPRQ SNCA

3.05e-051938353eaa0461618582a1754400624350d269d24e750a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAT4 PTPRG AFF3 UNC13C SNCA

3.13e-05194835b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL MAP1B NISCH RAPGEF4 PRKCA

3.13e-0519483592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Immature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

JUP CD19 SWAP70 SLC2A6 AFF3

3.13e-05194835f957cec2f309d726e095d18a7da32789dca92a36
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JUP CD19 SWAP70 AEBP1 AFF3

3.13e-05194835e9c907b8ec4329946338cca5ce8e954fa2cec37b
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-naive_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JUP CD19 SWAP70 AEBP1 AFF3

3.13e-051948354a4cc61193344bb151439f63d0584abddde47cf0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AEBP1 LOX PTPRQ ADGRB2 SNCA

3.13e-0519483543eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

JUP MAP1B LOX GGA1 CASK

3.13e-051948359441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK5 FAT4 AEBP1 LOX KIAA1755

3.21e-05195835f54bc4454270ff06e85596f98199372b50d0179f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 PTPRG AFF3 UNC13C SNCA

3.21e-051958350e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

KLHL29 PCSK5 GALNT10 MAML2 GAB2

3.21e-05195835a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JUP MAP1B LOX GGA1 CASK

3.21e-05195835fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL MAP1B NISCH RAPGEF4 PRKCA

3.21e-051958353e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLXIPL MAP1B NISCH RAPGEF4 PRKCA

3.21e-051958357796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 AFF2 MAP1B AEBP1 LOX

3.21e-051958355c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JUP MAP1B LOX GGA1 CASK

3.21e-0519583583d45ff5e5bc704448431149fffb2e4c1278f279
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRG AFF3 PRKCA MAML2 CASK

3.29e-05196835ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL29 MAP1B AEBP1 LOX HS6ST1

3.29e-05196835525d6c8a277364e624e7cc586275f8a891436b57
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B AEBP1 DTNA AFF3 KIAA1755

3.29e-051968351522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PTPRG AFF3 UNC13C MAML2 SNCA

3.29e-0519683522538376a95fe3afe8639a216a5497087aa94110
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B AEBP1 DTNA AFF3 KIAA1755

3.29e-051968351c8294014713684b50885e638668f2ce75f357f0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AEBP1 LOX PTPRQ ADGRB2 SNCA

3.29e-05196835545d2e4469924d333e3f655f559c899fa1260196
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL29 MAP1B DTNA LAMA1 LAMA3

3.37e-05197835f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MLXIPL PTPRG MAP1B AEBP1 LOX

3.37e-051978353bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MLXIPL PTPRG MAP1B AEBP1 LOX

3.37e-0519783517344464fdcc5ba0c03959696b97c195f11e644c
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

AHI1 MAP1B NISCH GGA1 DNMT1

3.37e-051978350fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MLXIPL PTPRG MAP1B AEBP1 LOX

3.37e-051978355b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 DTNA BCAN SNCA PLPPR1

3.45e-0519883550dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL29 PCSK5 FAT2 LAMA3 SNCA

3.45e-051988355374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL29 PCSK5 FAT2 LAMA3 SNCA

3.53e-0519983594a7867e800df352731796de8c24cba133c29622
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB3 AMER2 MAP1B PLPPR1 PLXNB1

3.53e-051998355d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB3 AMER2 MAP1B PLPPR1 PLXNB1

3.53e-051998359dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PKMYT1 JUP CD19 AEBP1 AFF3

3.53e-05199835ea75804c34989c99aab542e6d72617ed144819b6
ToppCell10x5'v1-week_12-13-Lymphocytic_B|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PKMYT1 JUP CD19 AEBP1 AFF3

3.53e-05199835713dfd8552635645db5e0b5721c64e5c9b4aa06c
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB3 AMER2 MAP1B PLPPR1 PLXNB1

3.53e-051998356fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 MAP1B AEBP1 LOX PENK

3.53e-05199835fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB3 AMER2 MAP1B PLPPR1 PLXNB1

3.53e-051998351bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
Drugguanine

RPGRIP1 SWAP70 PENK RAPGEF4 PRKCA RFFL RIC8A PLCD1 GIT2 CTNND1 GRM6 GGA1 DNMT1 CASK

4.41e-069028314CID000000764
Drugalpha-neoendorphin

PCSK5 PENK LAMA3 PSMD9

6.20e-0633834CID005311003
DrugPrilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A

KLHL29 SWAP70 DTNA CLPTM1 ADGRB2 SNCA PLPPR1

7.77e-061978373727_DN
DrugCefuroxime sodium salt [56238-63-2]; Down 200; 9uM; HL60; HT_HG-U133A

GALNT10 JUP DTNA SLC2A6 ANGEL1 CTNND1 SNCA

7.77e-061978372526_DN
DrugVanadates

PKMYT1 GALNT10 JUP SLC12A4 PTPRG MAP1B LOX SIMC1 LAMA1 ADGRB2 PRKCA SMARCE1 CTNND1 SNCA CDCP1 CASK

1.63e-0513028316ctd:D014638
Diseasehypertension (implicated_via_orthology)

SLC9A3 LOX NISCH PRKCA PLCD1

2.97e-05128825DOID:10763 (implicated_via_orthology)
Diseaseschizophrenia, intelligence, self reported educational attainment

GALNT10 ERBB3 AFF3 RAPGEF4 TMPRSS5 MAML2 CMAHP

5.13e-05346827EFO_0004337, EFO_0004784, MONDO_0005090
DiseaseCerebellar Diseases

AHI1 CASK

1.59e-047822C0007760
Diseaseguilt measurement

KLHL29 PRKCA TMPRSS5

1.90e-0440823EFO_0009595
Diseaseurinary bladder cancer (is_marker_for)

JUP ERBB3 PRKCA DNMT1

2.30e-04107824DOID:11054 (is_marker_for)
Diseasemyeloid white cell count

KLHL29 MLXIPL AHI1 SWAP70 CDH23 KIAA1755 QRICH1 GGA1 PLXNB1 DNMT1

2.69e-049378210EFO_0007988
Diseasesleep duration, high density lipoprotein cholesterol measurement

MLXIPL SLC12A4 CLPTM1 DEF6

3.68e-04121824EFO_0004612, EFO_0005271
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

PTPRQ CDH23 TECTA

3.91e-0451823cv:CN043650
DiseaseHbA1c measurement

KLHL29 MLXIPL JUP CTU2 SWAP70 AEBP1 CMAHP GAB2

5.79e-04675828EFO_0004541
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

PTPRQ CDH23

5.83e-0413822C1846647
Diseasecarcinoma (implicated_via_orthology)

JUP FAT4 ERBB3

7.63e-0464823DOID:305 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

ERBB3 CTU2 NISCH RIC8A TECTA GRM6 GGA1 DNAH9 PLXNB1 DNMT1

7.79e-0410748210C0006142
Diseaseneuroticism measurement

KLHL29 GALNT10 AFF2 PTPRG PRKCA TMPRSS5 QRICH1 SNCA CMAHP

9.43e-04909829EFO_0007660
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

SLC2A6 SURF2

1.01e-0317822EFO_0008011
DiseaseNonsyndromic genetic hearing loss

PTPRQ CDH23 TECTA

1.26e-0376823cv:C5680182
Diseasecardiomyopathy (is_implicated_in)

JUP DTNA

1.27e-0319822DOID:0050700 (is_implicated_in)
Diseasealkaline phosphatase measurement

MLXIPL SLC2A6 HS6ST1 SURF2 CLPTM1 UNC13C EDEM1 CMAHP DNMT1

2.02e-031015829EFO_0004533
DiseaseHepatolenticular Degeneration

LOX SNCA

2.02e-0324822C0019202
DiseaseHepatic Form of Wilson Disease

LOX SNCA

2.02e-0324822C1527352
Diseaseovarian carcinoma

BRD8 PTPRG LAMA3 CTNND1 CDCP1

2.03e-03321825EFO_0001075
Diseasehypertrophic cardiomyopathy

STRN PRKCA PLPPR1

2.17e-0392823EFO_0000538
Diseasecorpus collosum mid-posterior volume measurement

STRN UNC13C

2.20e-0325822EFO_0010300
Diseaseapolipoprotein B measurement

PCSK5 MLXIPL SLC2A6 NISCH CLPTM1 PRKCA CMAHP

2.48e-03663827EFO_0004615
Diseasechronic myeloid leukemia (is_marker_for)

GAB2 DNMT1

2.56e-0327822DOID:8552 (is_marker_for)
DiseasePR interval

JUP STRN DTNA KIAA1755 PRKCA CMAHP

2.58e-03495826EFO_0004462
Diseasehearing impairment

CDH23 TECTA DNMT1

2.60e-0398823C1384666

Protein segments in the cluster

PeptideGeneStartEntry
TEEQYAGSDPKRPEM

PTPRG

681

P23470
SADEPGLYMAQTGDP

ADGRB2

296

O60241
PTAYVRPMDGQDQAP

AFF3

231

P51826
PDEDYEYMNRQRDGG

ERBB3

1256

P21860
VAYQGGGEEMASPDE

AMER2

416

Q8N7J2
EDLPECVQVYSMGGP

DNMT1

1066

P26358
GEGYLSEMDNEPPVS

BRD8

651

Q9H0E9
DQGEVYVSEMEDQPP

BRD8

1051

Q9H0E9
NPETGEQVAMYSDLP

AHI1

871

Q8N157
PSLNPDGYEVAAQMG

AEBP1

666

Q8IUX7
QPEVDTYRPFQGTMG

CDCP1

756

Q9H5V8
TAYVRPMDGQDQAPD

AFF2

286

P51816
PNGEVRYSFEMVQPD

FAT4

1131

Q6V0I7
DYDNTPNDMEPDGMG

GIT2

591

Q14161
EYMPLPPEEAENGEN

API5

316

Q9BZZ5
NGQVEYSIMDGDPLG

CDH23

1776

Q9H251
MTREARNGEGEPYDP

QRICH1

531

Q2TAL8
ELYPMEPEEEANGSE

PENK

116

P01210
PIQTPREACYGDMDG

BCAN

216

Q96GW7
PYLNGDSPESANGDM

CASK

466

O14936
ENGPTEVDYSPSDMQ

MAP1B

1681

P46821
GSSNQEEEGPRMFPD

MAGEA2

86

P43356
KPETPGVYDMDGRNS

LAMA3

2511

Q16787
EMDRNITGHGYPDPN

DTX2

586

Q86UW9
ERPPQGSYMNVLEDA

KIAA1755

366

Q5JYT7
EQGRPYPMTDAERVD

GALNT10

91

Q86SR1
FQDYMEPEEGCQGSP

DYNC1LI2

181

O43237
CDVNGNDLDPMPRYD

PCSK5

191

Q92824
NQDYVPGERTPMLED

PLXNB1

1861

O43157
RVPPNYEGSDMVESD

FAT2

4326

Q9NYQ8
YNEMGDVDQFPPPET

GGA1

621

Q9UJY5
MQEPLLGAEGPDYDT

SLC2A6

1

Q9UGQ3
EAAQSMIPINEPYGD

JUP

681

P14923
DADEPGRVPTEDYMS

HS6ST1

391

O60243
APDRPPGENETYLMQ

IL20RA

526

Q9UHF4
GQQQEEEGMYPDPGL

NUTM1

396

Q86Y26
DDRGTPMAQSYDQNP

NUTM1

691

Q86Y26
TGNNEYINDPMAPEI

PTPRQ

491

Q9UMZ3
TPGPEMDVYQGRFQD

PLCD1

581

P51178
NRYGDDPGEQLMDPE

MAML2

291

Q8IZL2
EDQDNDPLTYGMSGP

CDHR2

51

Q9BYE9
TPVMFNENGDAPGRY

GRM6

456

O15303
EDADSYENMDNPDGP

CD19

526

P15391
RDDDDGPVSSQGYMP

DEF6

56

Q9H4E7
NEGEGDPPLYVNVNM

EDEM1

411

Q92611
SRVDGMVGDDPYNPY

LOX

161

P28300
RGDMVTEDADPYVQP

DTNA

691

Q9Y4J8
TMNPGYAGRTELPEN

DNAH9

1971

Q9NYC9
PPRNPEGDENYMEFL

SLC12A6

1111

Q9UHW9
HPEPYGLEDDQRSMG

CTNND1

276

O60716
MCQVGEDYGEPAPEE

CTU2

1

Q2VPK5
DSGDSEENYVPMQNP

GAB2

576

Q9UQC2
GMNEPLVDCEGYPRS

PSMD9

51

O00233
GILEDMPVDPDNEAY

SNCA

111

P37840
PYGVMETGSNNDRIP

RAPGEF4

161

Q8WZA2
NQGDMKPPSYDSDEG

STRN

126

O43815
DQMASPEVPIEAGQY

RPGRIP1

966

Q96KN7
MSIQPAEDPDDYDDG

SMARCE1

171

Q969G3
YNVPIPEGDEEGNME

PRKCA

286

P17252
EEVPPPQGARMQAYS

RFFL

16

Q8WZ73
YMDAPAPENGVRQEQ

LAMA1

1271

P25391
EEPPNYDEEMSGGIE

SLC9A3

721

P48764
QDVAYLQDMPRSPGD

SIMC1

281

Q8NDZ2
EDQMDGDGPRPREAF

SURF2

136

Q15527
QDGDLMKPYPGTEEE

PLPPR1

51

Q8TBJ4
PEDAYVGNADMIQPD

MLXIPL

271

Q9NP71
MAGGRPEGQYSEDED

RIC8A

426

Q9NPQ8
PPRNSEGDENYMEFL

SLC12A4

1046

Q9UP95
VEGDFAMAPRGPEQE

ANGEL1

41

Q9UNK9
RMIETDEDFNPFPGG

CMAHP

371

Q9Y471
DPTRVNEFGMSGEDP

CLPTM1

591

O96005
CGRYNGNPDDDLEMP

TECTA

1241

O75443
NPSSNIDPGDYVEMN

TRIM69

6

Q86WT6
QDGPSEMQEYFLRPG

ZNF460

96

Q14592
TPQDEGYDGPADDMV

UNC13C

916

Q8NB66
AGAGEVQEGDPRYMA

PKMYT1

261

Q99640
QELAPQDGSGYMDVG

SPEF1

126

Q9Y4P9
EEDVAENRYFEMGPP

NISCH

646

Q9Y2I1
ENRYFEMGPPDVEEE

NISCH

651

Q9Y2I1
DDQPPMEAQYAEEGP

TMPRSS5

6

Q9H3S3
IGEDYGVSMPPNDLA

ZNF496

251

Q96IT1
FRDDDEGPVSNQGYM

SWAP70

56

Q9UH65
DPAIEDQGGEYVQPM

TANGO2

206

Q6ICL3
SSEGPALGNMEAYEP

KLHL29

831

Q96CT2
YDSDNPRVRGDVGMA

MMUT

146

P22033
QRAEMPDGQYDPETG

MYOM3

1156

Q5VTT5