Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaminobutyraldehyde dehydrogenase (NAD+) activity

ALDH1A1 ALDH9A1

5.31e-0521462GO:0019145
GeneOntologyMolecularFunctionaminoacyltransferase activity

FBXO40 RNF169 HDAC4 PELI3 BIRC2 HUWE1 TRIM23 TGM1 GGTLC1 PRPF19 HERC2 HERC1 TRIM44

1.48e-0453214613GO:0016755
GeneOntologyBiologicalProcessmesenchyme migration

ACTA1 ACTA2 ACTC1 FOXF1

1.17e-0851454GO:0090131
GeneOntologyBiologicalProcessmyotube differentiation

NPHS1 HDAC4 ACTA1 ADAM12 EHD2 SORT1 DYRK1B MYOCD

2.13e-051641458GO:0014902
DomainActin/actin-like_CS

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

2.01e-07181445IPR020902
DomainACTINS_1

ACTBL2 ACTA1 ACTA2 ACTC1

2.32e-0781444PS00406
DomainACTINS_ACT_LIKE

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

2.71e-07191445PS01132
DomainActin

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

3.67e-06311445IPR004000
DomainActin

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

3.67e-06311445PF00022
DomainACTIN

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

3.67e-06311445SM00268
DomainActin_CS

ACTBL2 ACTA1 ACTA2 ACTC1

5.74e-06161444IPR004001
DomainACTINS_2

ACTBL2 ACTA1 ACTA2 ACTC1

7.46e-06171444PS00432
DomainCadherin_tail

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

1.84e-04371444PF15974
DomainCadherin_CBD

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

1.84e-04371444IPR031904
DomainCadherin_CS

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.00e-041091446IPR020894
DomainCADHERIN_1

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.43e-041131446PS00232
DomainCadherin

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.43e-041131446PF00028
DomainCADHERIN_2

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.55e-041141446PS50268
Domain-

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.55e-0411414462.60.40.60
DomainCA

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.67e-041151446SM00112
DomainCadherin-like

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

2.80e-041161446IPR015919
DomainCadherin_C

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

3.02e-04421444IPR032455
DomainCadherin_C_2

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

3.02e-04421444PF16492
DomainCadherin

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 FAT3 CDH23

3.07e-041181446IPR002126
DomainTerpenoid_cyclase/PrenylTrfase

FNTB C4A C4B

3.36e-04181443IPR008930
DomainNUT

NUTM2G NUTM2F

5.81e-0451442IPR024310
DomainNUT_N

NUTM2G NUTM2F

5.81e-0451442IPR024309
DomainAnaphylatoxin_comp_syst

C4A C4B

5.81e-0451442IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

5.81e-0451442IPR001840
DomainEHD_N

EHD2 SRL

5.81e-0451442IPR031692
DomainNUT

NUTM2G NUTM2F

5.81e-0451442PF12881
DomainEHD_N

EHD2 SRL

5.81e-0451442PF16880
DomainPAK_BD

PAK1 PAK2

8.68e-0461442IPR033923
DomainHECT

HUWE1 HERC2 HERC1

1.15e-03271443PF00632
DomainHECTc

HUWE1 HERC2 HERC1

1.15e-03271443SM00119
DomainHECT_dom

HUWE1 HERC2 HERC1

1.15e-03271443IPR000569
DomainHECT

HUWE1 HERC2 HERC1

1.15e-03271443PS50237
DomainANATO

C4A C4B

1.21e-0371442SM00104
DomainWASP_C

PAK1 PAK2

1.21e-0371442IPR011026
DomainANAPHYLATOXIN_2

C4A C4B

1.21e-0371442PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.21e-0371442PS01177
DomainANATO

C4A C4B

1.21e-0371442PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

1.21e-0371442IPR000020
DomainWD40_repeat

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC2 HERC1 DYNC1I2

1.25e-032721448IPR001680
DomainWD_REPEATS_2

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC2 HERC1 DYNC1I2

1.47e-032791448PS50082
DomainWD_REPEATS_REGION

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC2 HERC1 DYNC1I2

1.47e-032791448PS50294
DomainCadherin_2

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

1.59e-03651444PF08266
DomainCadherin_N

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

1.59e-03651444IPR013164
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.60e-0381442IPR019565
DomainThiol-ester_cl

C4A C4B

1.60e-0381442PF10569
DomainMacrogloblnA2_CS

C4A C4B

1.60e-0381442IPR019742
DomainA2M

C4A C4B

2.55e-03101442PF00207
DomainA2M_N_2

C4A C4B

2.55e-03101442IPR011625
DomainA2M_comp

C4A C4B

2.55e-03101442IPR011626
DomainA2M_recep

C4A C4B

2.55e-03101442PF07677
DomainA2M_comp

C4A C4B

2.55e-03101442PF07678
DomainA2M_N

C4A C4B

2.55e-03101442PF01835
DomainA2M_N

C4A C4B

2.55e-03101442IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

2.55e-03101442IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

2.55e-03101442PS00477
DomainA2M_N_2

C4A C4B

2.55e-03101442PF07703
DomainMacroglobln_a2

C4A C4B

2.55e-03101442IPR001599
DomainKinase-like_dom

ATR MAP3K8 RPS6KB1 MINK1 FN3K DYRK1B PAK1 PAK2 PNCK LTK FOXF1

3.23e-0354214411IPR011009
Domain-

PAK1 PAK2

3.70e-031214423.90.810.10
DomainWD40

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC1 DYNC1I2

4.00e-032591447PF00400
Domain-

DCAF8L2 WDR47 SORT1 WDHD1 STRN4 PRPF19 HERC1 DYNC1I2

4.35e-0333314482.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF8L2 WDR47 SORT1 WDHD1 STRN4 PRPF19 HERC1 DYNC1I2

4.51e-033351448IPR015943
DomainWD40

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC1 DYNC1I2

4.81e-032681447SM00320
DomainG_DYNAMIN_dom

EHD2 SRL

5.06e-03141442IPR030381
DomainG_DYNAMIN_2

EHD2 SRL

5.06e-03141442PS51718
DomainDynamin_GTPase

EHD2 SRL

5.80e-03151442IPR001401
DomainDynamin_SF

EHD2 SRL

5.80e-03151442IPR022812
DomainDynamin_N

EHD2 SRL

5.80e-03151442PF00350
DomainWD_REPEATS_1

WDR47 WDHD1 STRN4 PRPF19 HERC2 HERC1 DYNC1I2

5.85e-032781447PS00678
DomainAld_DH_CS_GLU

ALDH1A1 ALDH9A1

6.60e-03161442IPR029510
DomainPBD

PAK1 PAK2

6.60e-03161442SM00285
DomainC345C

C4A C4B

7.44e-03171442SM00643
DomainAld_DH_CS_CYS

ALDH1A1 ALDH9A1

7.44e-03171442IPR016160
DomainPBD

PAK1 PAK2

7.44e-03171442PF00786
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

ACTA1 ACTA2 ACTC1 PAK1 PAK2

2.49e-05471055M39829
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTA1 ACTA2 ACTC1 PAK1

1.15e-087150422465675
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTA1 ACTA2 ACTC1 PAK1

2.30e-088150414694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTA1 ACTA2 ACTC1 PAK2

2.30e-088150420147394
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTA1 ACTA2 ACTC1

7.86e-08315037780165
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RNF169 OFD1 ACTBL2 MINK1 ACTA1 HUWE1 SORT1 FAM171A1 PPP5C PTPRZ1 FECH PRPF19 HERC2 HERC1 TNS1 CPSF3 SNTB2 PPP6R3 VAT1

1.46e-0710491501927880917
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

HDAC4 CENPF RPS6KB1 MINK1 HUWE1 ADNP LDB2 WDR47 FAM171A1 NCAN STRN4 PAK1 UBA6 PAK2 TJAP1 HERC2 BSN TNS1

2.02e-079631501828671696
Pubmed

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.

ACTA1 ACTA2 ACTC1 MYOCD

9.70e-0718150415929941
Pubmed

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.

ACTA1 ACTA2 ACTC1 MYOCD

1.23e-0619150418316483
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTA1 ACTA2 ACTC1

1.56e-06615039971772
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTA1 ACTA2 ACTC1

1.56e-066150310074138
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTA1 ACTA2 ACTC1

1.56e-066150322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTA1 ACTA2 ACTC1

1.56e-06615031540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTA1 ACTA2 ACTC1

1.56e-066150311709093
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTA1 ACTA2 ACTC1

1.56e-066150310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTA1 ACTA2 ACTC1

1.56e-066150312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTA1 ACTA2 ACTC1

1.56e-066150323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTA1 ACTA2 ACTC1

1.56e-066150319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTA1 ACTA2 ACTC1

1.56e-066150321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTA1 ACTA2 ACTC1

1.56e-06615038661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTA1 ACTA2 ACTC1

1.56e-066150323017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTA1 ACTA2 ACTC1

1.56e-066150323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTA1 ACTA2 ACTC1

1.56e-06615039841925
Pubmed

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

RPS6KB1 ACTA1 ACTA2 ACTC1

1.88e-0621150423063798
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTA1 ACTA2 ACTC1

2.72e-067150322535526
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTA1 ACTA2 ACTC1

2.72e-067150318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTA1 ACTA2 ACTC1

2.72e-067150322640593
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTA1 ACTA2 ACTC1

2.72e-067150317504171
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

ACTA1 ACTA2 ACTC1

2.72e-06715039384381
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

ACTA1 ACTA2 ACTC1

2.72e-067150330289203
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ESPN CENPF PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 ACTBL2 ACTA1 ACTA2 NUCB1 SANBR ACTC1 SLC27A1 STRN4 PRPF19 GNAI3 ALDH1A1 BSN DYNC1I2 VAT1

4.23e-0614421502035575683
Pubmed

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

ACTA1 ACTA2 ACTC1

4.33e-068150320096780
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTA1 ACTA2 ACTC1

4.33e-068150323260110
Pubmed

Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

ACTA2 MYOCD IHH FOXF1

5.40e-0627150425631042
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTA1 ACTA2 ACTC1

6.48e-069150310556093
Pubmed

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

ACTA1 ACTA2 ACTC1

6.48e-069150312297046
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTA1 ACTA2 ACTC1

6.48e-06915038892894
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTA1 ACTA2 ACTC1

6.48e-069150318775311
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTA1 ACTA2 ACTC1

9.23e-061015031907279
Pubmed

HLA-association of serum levels of natural antibodies.

HLA-DQA1 C4A C4B

9.23e-0610150319167759
Pubmed

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

ACTA1 ACTA2 ACTC1

9.23e-0610150321749862
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTA1 ACTA2 ACTC1

9.23e-061015031991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTA1 ACTA2 ACTC1

9.23e-0610150323575248
Pubmed

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

MAP3K8 BCL6 C4A C4B

9.55e-0631150427022143
Pubmed

The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

ACTA1 ACTA2 ACTC1 FOXF1

1.09e-0532150423369715
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTA1 ACTA2 ACTC1

1.26e-0511150330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTA1 ACTA2 ACTC1

1.26e-0511150323294842
Pubmed

Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.

ACTA2 ACTC1 MYOCD

1.26e-0511150331513549
Pubmed

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.

ACTA1 ACTA2 ACTC1

1.26e-0511150322207710
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTA1 ACTA2 ACTC1

1.26e-0511150319639585
Pubmed

Functional significance of isoform diversification in the protocadherin gamma gene cluster.

PCDHGA11 PCDHGA7 PCDHGA6 BSN

1.39e-0534150422884324
Pubmed

SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.

ACTA1 ACTA2 ACTC1

1.68e-0512150331042497
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTA1 ACTA2 ACTC1

1.68e-0512150323071112
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FNTB ACTBL2 ACTA1 NUCB1 SHMT1 HUWE1 PPP5C WDHD1 UBXN7 STRN4 UBA6 PAK2 PRPF19 GNAI3 HERC1 ALDH9A1 DYNC1I2 PPP6R3 VAT1

1.74e-0514551501922863883
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

OFD1 FAM171A1 KANK1 STRN4 SNTB2 NOL8

1.79e-05125150629467281
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

1.85e-052150222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

1.85e-052150216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

1.85e-052150215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

1.85e-052150219062096
Pubmed

Activation of PAK1/2 during the shedding of platelet microvesicles.

PAK1 PAK2

1.85e-052150220523167
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

1.85e-052150219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

1.85e-05215022459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

1.85e-052150217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

1.85e-052150212207352
Pubmed

Transcriptional regulation of ataxia-telangiectasia and Rad3-related protein by activated p21-activated kinase-1 protects keratinocytes in UV-B-induced premalignant skin lesions.

ATR PAK1

1.85e-052150228692051
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

1.85e-052150227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

1.85e-052150222387014
Pubmed

Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.

ACTA1 ACTC1

1.85e-052150220706863
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

1.85e-052150223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

1.85e-052150223918728
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

1.85e-05215023037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

1.85e-052150211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

1.85e-05215024216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

1.85e-05215026950384
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

1.85e-05215028660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

1.85e-05215028428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

1.85e-052150224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

1.85e-052150221345967
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

1.85e-05215022572548
Pubmed

The complement component C4 of mammals.

C4A C4B

1.85e-05215022302180
Pubmed

A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

ACTA1 ACTC1

1.85e-05215023023046
Pubmed

Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.

PAK1 PAK2

1.85e-052150215047871
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

1.85e-052150222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

1.85e-052150218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

1.85e-052150229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

1.85e-05215026589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

1.85e-052150225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

1.85e-052150217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

1.85e-05215026149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

1.85e-05215026149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

1.85e-052150212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

1.85e-05215023542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

1.85e-05215022387317
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

1.85e-052150216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

1.85e-05215027365238
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

1.85e-05215027391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

1.85e-052150217971360
Pubmed

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation.

BACH2 BCL6

1.85e-052150224277074
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

1.85e-052150229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

1.85e-052150217971229
Pubmed

Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.

ACTA1 ACTC1

1.85e-05215023075543
InteractionICE2 interactions

RNF169 OFD1 ACTA2 MUC5B SORT1 DYRK1B PIPSL

1.71e-06771507int:ICE2
InteractionFBXO40 interactions

FBXO40 ACTBL2 ACTA2 ACTC1

3.78e-06151504int:FBXO40
InteractionNAA80 interactions

BACH2 ACTBL2 ACTA2 ACTC1

3.78e-06151504int:NAA80
InteractionDYNLL2 interactions

ATMIN FBXO40 OFD1 ADNP FAM171A1 KANK1 STRN4 PAK1 BSN DYNC1I2

2.85e-0526315010int:DYNLL2
InteractionTPTE2 interactions

OFD1 POLE KIAA0232 HUWE1 STRN4 HERC1

3.88e-05841506int:TPTE2
InteractionPFN3 interactions

ACTBL2 ACTA2 ACTC1

4.67e-05101503int:PFN3
InteractionANGPTL8 interactions

ACTBL2 ACTA1 ACTA2

4.67e-05101503int:ANGPTL8
InteractionGPSM1 interactions

CHAMP1 TRIM23 USHBP1 GNAI3 PPP6R3

5.51e-05551505int:GPSM1
InteractionPHACTR2 interactions

ACTBL2 ACTA2 ACTC1 PRPF19

6.06e-05291504int:PHACTR2
InteractionIL17RE interactions

FAT3 ACTBL2 ACTA2

6.38e-05111503int:IL17RE
InteractionWASH8P interactions

ACTBL2 ACTA2 ACTC1

6.38e-05111503int:WASH8P
InteractionPPIAL4G interactions

PCDHGA11 FAT3 ACTBL2 EHD2

6.95e-05301504int:PPIAL4G
InteractionZBBX interactions

POLE KIAA0232 FAT3 HERC1

7.93e-05311504int:ZBBX
GeneFamilyActins

ACTA1 ACTA2 ACTC1

2.13e-066873929
GeneFamilyClustered protocadherins

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1

2.55e-046487420
GeneFamilyWD repeat domain containing

DCAF8L2 WDR47 WDHD1 STRN4 PRPF19 HERC1 DYNC1I2

2.70e-04262877362
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

8.06e-0498721234
CoexpressionGSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP

PDE6H ATR KIAA0232 ACTA2 ACTC1 BIRC2 ADNP ADAM12 FAM171A1

1.98e-061981489M5222
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_DN

ATR FNTB BIRC2 AGPS BCL6 MDH1 TRIM23 PTPRZ1 MCM3AP PAK1 TRIM44 SNTB2

1.95e-0548114812M3898
CoexpressionMCCLUNG_CREB1_TARGETS_DN

POU3F4 LDB2 C4A C4B PNCK

2.28e-05601485MM654
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM FAT3 ACTA2 ACTC1 POU3F4 MDH1 PNCK TNS1

1.74e-071791508e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM FAT3 ACTA1 ACTA2 SRL MYOCD PNCK TNS1

3.76e-0719815081e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FBXO40 SYNM ACTA1 ACTA2 ACTC1 MYOCD PNCK TNS1

3.91e-071991508534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTA2 ACTC1 GSDMC KANK1 PTPRZ1 MYOCD PNCK

1.21e-0616015078624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTA2 ACTC1 GSDMC KANK1 PTPRZ1 MYOCD PNCK

1.21e-0616015079de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

SYNM FAT3 ACTA2 ACTC1 C1QL1 MYOCD FOXF1

1.49e-061651507531804467601e1ee1f771cffa21501f6d464ae10
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA1 ACTA2 ACTC1 EHD2 GGTLC1 MYOCD

2.04e-061731507ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA1 ACTA2 ACTC1 EHD2 GGTLC1 MYOCD

2.04e-061731507b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE6H FAT3 ACTA2 SORT1 KANK1 MYOCD PNCK

2.12e-061741507197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE6H FAT3 ACTA2 SORT1 KANK1 MYOCD PNCK

2.12e-0617415072eee7b5471672b439f95eba11494c2adf8cb7006
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ACTA2 ACTC1 KANK1 C4A MYOCD PNCK FOXF1

2.96e-061831507a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK FOXF1

3.07e-06184150739168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK ALDH1A1

3.41e-0618715073912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SYNM PCDHGA7 LDB2 LTK NOS2 FOXF1 VAT1

3.54e-061881507fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

SYNM PCDHGA7 LDB2 LTK NOS2 FOXF1 VAT1

3.54e-061881507cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD C4B

3.54e-061881507e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CENPF FAT3 SHMT1 XRCC3 WDHD1 MYOCD FOXF1

3.79e-061901507e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM FAT3 ACTA2 ACTC1 MDH1 MYOCD ALDH1A1

3.92e-061911507de2cd94ee88a7754f86d39469e38374d668210c7
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK ALDH1A1

4.35e-06194150793bc72a933ccc6a760e5353f072afb606571c6fc
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 PNCK ALDH1A1 TNS1

4.35e-061941507d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD TNS1

4.81e-061971507d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD TNS1

4.81e-06197150768c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 ACTC1 SORT1 SRL MYOCD TNS1

4.97e-0619815077dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA1 ACTA2 ACTC1 SORT1 MYOCD TNS1

5.31e-0620015072bc7f462a551292de2501028164573935232f899
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA1 ACTA2 ACTC1 SORT1 MYOCD TNS1

5.31e-0620015078b80a65b69b36ed405214564b939452c90aa40d6
ToppCellfacs-Heart-LV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO40 CEBPE HLA-DQA1 MMP25 FECH FOXF1

9.11e-0614315068f82b3c3331f20c6ded36dbfb9a48dbd9f099f93
ToppCellfacs-Heart-LV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO40 CEBPE HLA-DQA1 MMP25 FECH FOXF1

9.11e-06143150652832321cc848739ff6483f467d57c50c8b7395c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

1.29e-051521506bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

1.29e-051521506ee329249a034a969a16b26a224aa04249d67382d
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OFD1 HLA-DQA1 MAP3K8 BCL6 PIK3R6 PAK1

1.85e-051621506448602d5ff8b5be9614c63540a4d0fe6bdaf23b4
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESPN WDR47 USHBP1 C4A TNS1 FOXF1

2.12e-051661506aa2df07eff323ded751ced8938af08223d7f2029
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NUDT19 ESPN BACH2 RPS6KB1 PNCK PDCL

2.12e-051661506dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESPN WDR47 USHBP1 C4A TNS1 FOXF1

2.12e-051661506695298a94d62b8adab083900003ec636fbaae5d9
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

MINK1 PELI3 WDR47 MMP25 SLC4A5 PPP6R3

2.20e-0516715061036ac1ef9440612500137af9d1929672b077e4d
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 NRXN2 SLC27A1 SRL PNCK KHK

2.59e-05172150630916a902c151907745756d14327e24adc34afef
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 EHD2 SRL MYOCD TNS1

2.86e-051751506294a70786260c9a2b1ba16c88819d786698609e7
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 C1QL1 NRXN2 PTPRZ1 NCAN CCDC171

2.86e-051751506d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 C1QL1 NRXN2 PTPRZ1 NCAN CCDC171

2.86e-0517515061d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 EHD2 SRL MYOCD TNS1

2.86e-051751506798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DQA1 SLC51B SLC15A4 SLC27A1 PNCK TNS1

2.95e-051761506d4075796c38b775fe721abb47426e662a0d415e3
ToppCellCOPD-Stromal-SMC|COPD / Disease state, Lineage and Cell class

SYNM ACTA2 ACTC1 SRL MYOCD TNS1

3.25e-0517915065c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 NRXN2 SLC27A1 PNCK KHK TNS1

3.25e-051791506d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

MBTPS1 SYNM ACTA2 SHMT1 ACTC1 WDR47

3.25e-05179150683506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 C1QL1 NRXN2 PTPRZ1 NCAN C4B

3.45e-0518115061037051eb82313c13346617b33f3c4c648181c4d
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SYNM ACTA2 C1QL1 SRL MYOCD LTK

3.67e-0518315064617b18da8d699a44e4c47980197b1e7eb951470
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 MYOCD PNCK TNS1 FOXF1

3.67e-05183150661a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DQA1 MAP3K8 BCL6 PIK3R6 PAK1 HSH2D

3.79e-0518415064f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXO40 CENPF ACTA2 ACTC1 C1QL1 PTPRZ1

3.79e-051841506d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAM12 PIK3R6 PAK1 ALDH1A1 TNS1 VAT1

3.90e-0518515063fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

BACH2 ACTA2 ACTC1 SRL MYOCD FOXF1

4.14e-05187150635f25780d113f60bf4c13749013c09612ee4ff41
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

SYNM ACTA2 ACTC1 EHD2 MYOCD C4B

4.27e-051881506b66264e8f8d536ed2beec31e6746c687718f239b
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO40 ACTA2 ACTC1 PTPRZ1 PNCK IHH

4.27e-05188150661f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO40 ACTA2 ACTC1 PTPRZ1 PNCK IHH

4.27e-0518815067553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

SYNM ACTA2 ACTC1 SORT1 SRL MYOCD

4.27e-0518815069ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 C1QL1 KANK1 NRXN2 PTPRZ1 NCAN

4.27e-051881506006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 C1QL1 KANK1 NRXN2 PTPRZ1 NCAN

4.27e-051881506d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK

4.53e-051901506e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBXO40 SYNM ACTA1 ACTC1 SRL MYOCD

4.53e-051901506918ad5037881212008f9f69d5df5da91fd01422c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

FBXO40 FN3K DGLUCY KANK1 SRL MYOCD

4.53e-051901506fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

SYNM ACTA2 ACTC1 BCL6 SRL MYOCD

4.66e-051911506fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ESPN MUC5B SLC51B LCN15 PNCK IHH

4.80e-0519215069f7e0d610741288d0779bd7c02852c791431e4ea
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ACTA2 ACTC1 KANK1 PTPRZ1 MYOCD PNCK

4.80e-05192150687c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK

4.94e-051931506173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA1 ACTA2 ACTC1 SORT1 MYOCD

4.94e-0519315065260ac95a15cc43a19909badad0c7e3854da920d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 ACTC1 MDH1 MYOCD PNCK

4.94e-051931506b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA1 ACTA2 ACTC1 SORT1 MYOCD

4.94e-0519315065ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

MAP3K8 APMAP MXD4 SLC15A4 HSH2D CHST2

5.08e-051941506c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 MDH1 MYOCD ALDH1A1 FOXF1

5.08e-05194150612a2c60303607b8b5812405ad216d0612c56c64b
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 MDH1 MYOCD ALDH1A1 FOXF1

5.08e-05194150615060cc25baf49dd04d9c20499e28718610ef754
ToppCell10x5'-Liver-Lymphocytic_NK|Liver / Manually curated celltypes from each tissue

MAP3K8 APMAP LDB2 SLC15A4 HSH2D CHST2

5.08e-0519415060b78f4ed84bbaca9f72f005c16c7492bb01d4328
ToppCell10x5'-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

MAP3K8 APMAP MXD4 SLC15A4 HSH2D CHST2

5.23e-051951506c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 EHD2 MYOCD TNS1 FOXF1

5.23e-05195150644f67437ea65d530133a0240b17f9860d9cc0e99
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTA2 ACTC1 KANK1 PTPRZ1 MYOCD C4B

5.23e-05195150643d372373367b71243c6ea958aedccde4478618f
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK|lymph-node_spleen / Manually curated celltypes from each tissue

MAP3K8 APMAP LDB2 SLC15A4 HSH2D CHST2

5.38e-05196150693ff94fc2b2ca8bd6a6492cbc0b402daf5d63ea2
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 EHD2 SRL MYOCD TNS1

5.38e-051961506ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SYNM ACTA1 ACTA2 ACTC1 SORT1 MYOCD

5.38e-051961506541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell(0)_Myeloid-(010)_cDC|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

OFD1 CENPF HLA-DQA1 BACH2 PRPF19 SDS

5.38e-051961506ea8cf29a9d4d177d092b0568fd4601cd7f906884
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

5.38e-051961506c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

5.38e-0519615062f76f050083483f0880639e6c34ff349caac3503
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 EHD2 MYOCD TNS1 FOXF1

5.38e-05196150620dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM ACTA2 EHD2 SRL MYOCD TNS1

5.38e-0519615066d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DQA1 PELI3 MDH1 SORT1 ALDH1A1 VAT1

5.53e-051971506d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DQA1 PELI3 MDH1 SORT1 ALDH1A1 VAT1

5.53e-05197150633f2fe101ae5744eea3915add37e60aa398bb97f
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DQA1 PELI3 MDH1 SORT1 ALDH1A1 VAT1

5.53e-0519715065e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCellFibroblast|World / shred by cell class for bronchial biopsy

SYNM ACTBL2 ACTA2 ACTC1 MYOCD FOXF1

5.53e-0519715068bf9846228b6b6721b10375fe54a2fb389ff64a6
ToppCellSevere_COVID-19-Myeloid-TRAM2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

HLA-DQA1 PELI3 MDH1 SORT1 ALDH1A1 VAT1

5.53e-0519715068a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DQA1 PELI3 MDH1 SORT1 ALDH1A1 VAT1

5.53e-0519715069262785807faeb32417fad7ef202405053e453e2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 CDH23 C4A MYOCD TNS1

5.53e-051971506ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA1 ACTA2 ACTC1 MYOCD TNS1

5.53e-051971506470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNM ACTA2 SORT1 SRL MYOCD TNS1

5.69e-05198150689986c7756541df364df516329d10775ba0e78a4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

5.69e-05198150677288df94286382170a266474ab85960519e8449
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ACTA2 ACTC1 EHD2 SRL MYOCD

5.69e-0519815062ee195f20a4f91fa1dcad9eaf96d6086e3b0fb4a
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 MYOCD PNCK TNS1 FOXF1

5.69e-051981506c12e7511628db819a52959bb68580e27c00c2e41
ToppCellnormal_Lymph_Node-T/NK_cells-NK|T/NK_cells / Location, Cell class and cell subclass

MAP3K8 APMAP LDB2 SLC15A4 HSH2D CHST2

5.69e-05198150675e94298bf03d755fef46df685437d0d29fdbca9
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 MYOCD PNCK TNS1 FOXF1

5.69e-05198150622e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 ACTC1 SRL MYOCD TNS1

5.85e-0519915060a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 ACTC1 MYOCD PNCK TNS1

5.85e-051991506056a28c36cd58dc695a5ae6f29b62135d6aad819
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM ACTA2 ACTC1 SRL MYOCD TNS1

5.85e-051991506c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-MAIT|ICU-SEP / Disease, condition lineage and cell class

OFD1 SYNM MINK1 FAM171A1 KANK1 CCDC171

5.85e-0519915062f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCelldistal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LDB2 USHBP1 LTK NOS2 FOXF1 VAT1

6.02e-052001506e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ComputationalCoA and fatty acid metabolism.

SHMT1 MDH1 ALDH1A1 ALDH9A1

2.18e-0519974MODULE_305
Drugmicrocystin-LR

HDAC4 ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 MDH1 PPP5C PAK1 NOS2

1.18e-0812914710CID000445433
DrugNsc687160

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

8.39e-08181475CID005459290
Drugtolytoxin

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.13e-07191475CID006440827
DrugNSC312786

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.96e-07211475CID000329495
DrugAC1L8NVR

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.96e-07211475CID000384633
DrugL-Carnosine

ACTA1 ACTA2 ACTC1 ACTRT2 FN3K SLC15A4 CNDP1

4.62e-07731477CID000009369
Drugdihydrosphingosine

MBTPS1 MAT1A ACTBL2 ACTA1 ACTA2 NUCB1 ACTC1 ACTRT2 AGXT

4.65e-071461479CID000003126
DrugAC1L9EF8

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 TGM1 SDS

7.96e-07791477CID000443315
Drugazaspiracid

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.31e-06301475CID006451158
Drug3-methylhistidine

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 CNDP1

1.46e-06551476CID000064969
DrugAC1L1HS4

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.83e-06321475CID000004267
Drugdihydrocytochalasin B

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 TGM1

2.01e-06581476CID000003064
DrugNSC613009

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 PAK1 NOS2 SLC4A5

2.08e-061301478CID000003800
Drugacetaldehyde

OFD1 FNTB ACTBL2 ACTA1 ACTA2 SHMT1 ACTC1 ACTRT2 PPP5C ALDH1A1 ALDH9A1 SDS

2.11e-0633814712CID000000177
DrugmDia

MBTPS1 ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 SLC4A5

2.41e-06931477CID000128346
DrugN,N'-p-phenylenedimaleimide

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

2.51e-06341475CID000076765
Drug1,N6-ethenoadenosine 5'-diphosphate

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

2.51e-06341475CID000001312
DrugAC1NRBPQ

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 SUPT7L TNS1 CNDP1

3.09e-061371478CID005288569
DrugDE gel

ACTBL2 ACTA1 ACTA2 ACTC1 POU3F4 ACTRT2 BSN NOS2

4.25e-061431478CID000008146
DrugML-9

MBTPS1 RPS6KB1 ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 PAK1

5.22e-061471478CID000004217
DrugChlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A

CEBPE MAP3K8 PCDHGA1 POU3F4 C1QL1 MMP25 TJAP1 CHST2 TNS1

5.57e-0619714792279_UP
Drugammonia

MAT1A APMAP ACTBL2 ACTA1 ACTA2 SHMT1 ACTC1 ACTRT2 MDH1 FN3K TGM1 AGXT NOS2 SDS

5.75e-0650914714CID000000222
Drugm2-19

ACTA1 ACTA2 ACTC1 ACTRT2

6.00e-06191474CID000079129
Drugepsilon-ATP

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

6.51e-06411475CID000162262
Drug9-beta-D-arabinofuranosylguanine

MBTPS1 PDE6H POLE RPS6KB1 ACTBL2 ACTA1 ACTA2 NUCB1 ACTC1 ACTRT2 SORT1 TGM1 SUPT7L PAK1 PAK2 C4A GNAI3 NOS2

8.74e-0684314718CID000000765
DrugAC1L8FNU

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

9.29e-06441475CID000425429
DrugSIRIUS

SYNM ACTA1 ACTA2 ACTC1 ACTRT2 LTK

1.06e-05771476CID000091750
DrugNpCaM

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.43e-05481475CID000122259
DrugAC1Q6LQU

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

1.43e-05481475CID000072380
Drugplakin

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 SNTB2

1.53e-05821476CID000018752
DrugFormyl

ACTBL2 ACTA1 ACTA2 SHMT1 ACTC1 ACTRT2 HSH2D NOS2 CNDP1

2.52e-052381479CID000123370
Drugaldonates

SHMT1 HUWE1 AGXT KHK ALDH9A1 SDS

2.61e-05901476CID000000752
Drugmethyl ethyl ketone

MBTPS1 MAP3K8 BACH2 RPS6KB1 ACTA1 ACTA2 ACTC1 ACTRT2 ADAM12 PPP5C PAK1 PAK2 MYOCD NOS2

2.82e-0558714714CID000006569
DrugCID5288653

ACTA1 ACTA2 ACTC1 ACTRT2

3.03e-05281474CID005288653
Drugarabinosyladenine

PDE6H MAT1A ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 AGPS MDH1 POLR3B AGXT C4A BSN NOS2 CPSF3 SDS

3.49e-0576214716CID000000191
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A

ING1 MAP3K8 MINK1 C1QL1 TJAP1 POLL PRR14L PDCL

3.63e-0519214784395_DN
Drugtert-butylbenzene

MAT1A C4A

4.14e-0521472CID000007366
DrugNSC3096

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 SLC4A5

4.22e-05981476CID000002832
DrugBemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A

RPH3AL KIAA0232 MINK1 ADAM12 C1QL1 UBA6 TJAP1 TNS1

4.51e-0519814786668_DN
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

RPH3AL CENPF MINK1 ADAM12 MXD4 TRIM23 SUPT7L TNS1

4.51e-0519814787303_DN
Drugmonomethyl phthalate

ATMIN CEBPE HDAC4 ATR CENPF RPS6KB1 ACTA1 GLOD4 ADNP MXD4 SORT1 WDHD1 UBA6 POLL ALDH1A1 CHST2 FOXF1 PPP6R3

4.69e-0595714718ctd:C517284
DrugPI(3,4,5)P3

RPS6KB1 ACTA1 ACTA2 ACTC1 ACTRT2 SUPT7L TNS1

5.07e-051481477CID000643963
Drugoryzalin

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

5.45e-05631475CID000029393
Drugberyllium fluoride

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 AGPS

5.59e-051031476CID000024589
Drugcarbodiimide

MAT1A ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 ALDH9A1

5.76e-051511477CID000009864
Drugnitroglycerin

ACTBL2 ACTA1 ACTA2 ACTC1 BIRC2 ACTRT2 ALDH1A1 NOS2

5.96e-052061478CID000004510
Drug5-IAF

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

6.82e-05661475CID000123822
DrugNSC406942

FNTB SYNM APMAP ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 MDH1 FECH KHK BSN NOS2

7.92e-0556514713CID000001115
DrugAC1NSKFN

ACTA1 ACTA2 ACTC1 ACTRT2

8.37e-05361474CID005311324
Drugsuccinic semialdehyde

SHMT1 MDH1 ALDH1A1 ALDH9A1 CNDP1

8.45e-05691475CID000001112
DrugAC1L1ERT

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

8.45e-05691475CID000002920
Drugcaged ATP

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2

9.05e-05701475CID000123806
DrugAC1MNW2N

ACTA1 ACTA2 ACTC1 ACTRT2 MYOCD

9.05e-05701475CID003359490
Drugkabiramide C

ACTBL2 ACTC1 C4A

9.11e-05141473CID005288658
DrugHU-211

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 NOS2

9.83e-051141476CID000107778
Drugauxin

FNTB ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 AGPS ALDH9A1

1.07e-042241478CID000000801
DrugAC1L1GZB

ACTA1 ACTA2 ACTC1 ACTRT2 PAK2 C4A CNDP1

1.08e-041671477CID000003908
DrugC3H2N2O3S

ACTA1 ACTA2 ACTC1 ACTRT2 PAK1

1.18e-04741475CID000448652
DrugCo-protoporphyrin IX

ACTA1 ACTA2 ACTC1 ACTRT2 FECH NOS2

1.19e-041181476CID000004972
DrugPb m

ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 CHST2

1.19e-041181476CID006327255
Drug2-aminothiophenol

C4A C4B

1.24e-0431472ctd:C005464
DrugAC1LD8HW

ACTA1 ACTA2 ACTC1 ACTRT2 PRPF19

1.26e-04751475CID000644061
DrugC2-ceramide

MBTPS1 CEBPE ACTBL2 ACTA1 ACTA2 ACTC1 ACTRT2 ADNP NOS2

1.28e-042941479CID000002505
Drug5'-N-ethylcarboxamidoadenosine

POLE ACTA1 ACTA2 ACTC1 ACTRT2 BSN NOS2

1.40e-041741477CID000104795
Drugsulfobetaine

MAT1A SHMT1 SDS

1.68e-04171473CID000160765
DrugNSC-614616

SHMT1 AGXT SDS

1.68e-04171473CID000000690
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1 MYOCD

6.61e-10101455DOID:13832 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1

3.86e-0881454DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1

3.86e-0881454DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1

3.86e-0881454DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1

3.86e-0881454DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTBL2 ACTA1 ACTA2 ACTC1

1.15e-07101454DOID:10486 (implicated_via_orthology)
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA1 MYOCD

2.68e-05711455EFO_0007878, EFO_0007979
DiseasePneumoconiosis

ATR CDH23 PTPRZ1

4.07e-05141453C0032273
DiseaseBagassosis

ATR CDH23 PTPRZ1

4.07e-05141453C0004681
DiseaseProteinuria

NPHS1 HLA-DQA1 PAK1 PAK2

5.95e-05431454C0033687
DiseaseStomach Neoplasms

ATR ING1 POLE ACTC1 BIRC2 XRCC3 URM1 PRPF19

1.16e-042971458C0038356
DiseaseMalignant neoplasm of stomach

ATR ING1 POLE ACTC1 BIRC2 XRCC3 URM1 PRPF19

1.24e-043001458C0024623
DiseaseSquamous cell carcinoma of oropharynx

ATR ING1

1.43e-0441452C0280313
DiseaseSarcosine measurement

PCDHGA7 PCDHGA6 PCDHGA1

1.92e-04231453EFO_0021668
Diseasematrilysin measurement

MMP25 CEP126

2.38e-0451452EFO_0008227
Diseasemental development measurement

PCDHGA7 PCDHGA6 PCDHGA1

2.47e-04251453EFO_0008230
Diseaseglucocorticoid receptor gene expression measurement

KIAA0232 LDB2 SLC15A4

3.12e-04271453EFO_0600079
DiseaseHyalinosis, Segmental Glomerular

NPHS1 ACTA2 NOS2

3.48e-04281453C0086432
Diseasebody mass index, vital capacity

HLA-DQA1 IHH

3.55e-0461452EFO_0004312, EFO_0004340
Diseaserhegmatogenous retinal detachment

FAT3 LDB2

3.55e-0461452EFO_0005240
DiseaseLupus Erythematosus, Systemic

HLA-DQA1 SLC15A4 C4A C4B

4.21e-04711454C0024141
DiseaseLiver diseases

ACTA2 SORT1 TGM1 NOS2

4.44e-04721454C0023895
DiseaseLiver Dysfunction

ACTA2 SORT1 TGM1 NOS2

4.44e-04721454C0086565
Diseasetumor necrosis factor receptor superfamily member 6 measurement

HLA-DQA1 ACTA2

4.96e-0471452EFO_0010610
Diseasehelix rolling

FECH CCNYL2

6.59e-0481452EFO_0007670
Diseaseendometrial cancer (implicated_via_orthology)

ATR POLE

6.59e-0481452DOID:1380 (implicated_via_orthology)
DiseaseFocal glomerulosclerosis

NPHS1 ACTA2 NOS2

7.37e-04361453C0017668
Diseasecentral nervous system non-hodgkin lymphoma

HLA-DQA1 BACH2

8.44e-0491452MONDO_0044887
Diseasebreast cancer (is_implicated_in)

HLA-DQA1 SHMT1 BIRC2 XRCC3 PAK1

8.94e-041501455DOID:1612 (is_implicated_in)
DiseaseGraves' disease (is_implicated_in)

HLA-DQA1 C4A C4B

9.33e-04391453DOID:12361 (is_implicated_in)
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [1] measurement

GATAD2A NCAN

1.05e-03101452EFO_0800499
Diseasevascular endothelial function measurement

HDAC4 ADAM12 PTPRZ1 TRIM44

1.47e-03991454EFO_0803369
Diseaseselective IgA deficiency disease

HLA-DQA1 CDH23 FAM171A1

1.51e-03461453EFO_1001929
Diseaserac GTPase-activating protein 1 measurement

HLA-DQA1 C4B

1.53e-03121452EFO_0801985
DiseaseLiver Cirrhosis, Experimental

RPH3AL MAP3K8 APMAP ACTA2 MDH1 KANK1 L3HYPDH ALDH1A1 NOS2 SDS CNDP1

1.59e-0377414511C0023893
DiseaseGenetic chronic primary adrenal insufficiency

HLA-DQA1 BACH2

1.81e-03131452Orphanet_101960
Diseaseactinic keratosis

HLA-DQA1 HERC2

2.10e-03141452EFO_0002496
DiseaseC-C motif chemokine 19 measurement

HLA-DQA1 BSN

2.10e-03141452EFO_0008047
Diseasecancer (implicated_via_orthology)

ING1 POLE KANK1 FECH LTK PIPSL

2.16e-032681456DOID:162 (implicated_via_orthology)
DiseaseCholestasis

SORT1 SLC51B KANK1 NOS2

2.16e-031101454C0008370
Diseasehyperinsulinism (biomarker_via_orthology)

RPS6KB1 SLC27A1

2.41e-03151452DOID:2018 (biomarker_via_orthology)
Diseaselevel of triacylglycerol (56:6) in blood serum

GATAD2A NCAN

2.75e-03161452OBA_2020007
Diseasekeratinocyte carcinoma

HLA-DQA1 BACH2 KANK1 HERC2

2.78e-031181454EFO_0010176
DiseaseFEV/FEC ratio

HDAC4 HLA-DQA1 KIAA0232 PCDHGA1 BACH2 CDH23 ADAM12 LDB2 SLC51B KANK1 CHST2 HERC1 CCDC171 TNS1

2.99e-03122814514EFO_0004713
DiseaseBenign neoplasm of stomach

ATR POLE

3.11e-03171452C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR POLE

3.11e-03171452C0496905
DiseaseCarcinoma in situ of stomach

ATR POLE

3.11e-03171452C0154060
DiseaseMHPG measurement, 5-HIAA measurement

ADAM12 CCDC171

3.11e-03171452EFO_0005132, EFO_0005133
DiseaseHereditary Diffuse Gastric Cancer

ING1 ACTC1 BIRC2 XRCC3 URM1 PRPF19

3.35e-032931456C1708349
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

BACH2 RPS6KB1 ACTA2 PPP5C BSN NOS2

3.46e-032951456EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

HERC1 BSN

3.48e-03181452HP_0002373
DiseaseMalignant neoplasm of endometrium

ATR POLE

3.48e-03181452C0007103
DiseaseCarcinoma in situ of endometrium

ATR POLE

3.48e-03181452C0346191
DiseaseChronic myeloproliferative disorder

ATR CENPF

3.88e-03191452C1292778
Diseasesquamous cell carcinoma

HLA-DQA1 BACH2 HERC2

4.42e-03671453EFO_0000707
DiseaseLymphoma, Diffuse

SHMT1 BCL6

4.74e-03211452C3714542
DiseaseStomach Carcinoma

ATR POLE

4.74e-03211452C0699791
DiseaseLow Grade Lymphoma (neoplasm)

SHMT1 BCL6

4.74e-03211452C0079747
DiseaseLymphoma, Intermediate-Grade

SHMT1 BCL6

4.74e-03211452C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

SHMT1 BCL6

4.74e-03211452C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

SHMT1 BCL6

4.74e-03211452C0079757
DiseaseLymphoma, Undifferentiated

SHMT1 BCL6

4.74e-03211452C0024306
Diseasevitiligo (is_implicated_in)

HLA-DQA1 C4A

4.74e-03211452DOID:12306 (is_implicated_in)
DiseaseReticulosarcoma

SHMT1 BCL6

4.74e-03211452C0024302
DiseaseLymphoma, Mixed-Cell

SHMT1 BCL6

4.74e-03211452C0024304
Diseaserenal cell carcinoma (is_implicated_in)

PAK1 C4A C4B

4.81e-03691453DOID:4450 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
PSHSGPMEFEGTSEG

USHBP1

141

Q8N6Y0
GHGGDTLDAEPMLAG

AMER3

661

Q8N944
GHAFSEMQECGAGTP

CEP295NL

376

Q96MC4
TDGVAEPMHGSLAGV

ADNP

1081

Q9H2P0
FLATEHQEPGLMGDG

BACH2

556

Q9BYV9
SMAGEHIQLPGGSFG

ALDH9A1

126

P49189
GPGELGDMCEHEASI

CEBPE

26

Q15744
MGLDGATYDLEGHPQ

C4B

1686

P0C0L5
HFDDIGPSVVMASPG

CPSF3

316

Q9UKF6
PSFIGMESAGIHETT

ACTA1

266

P68133
SGEFGPRHMVSSIVG

ACTRT2

26

Q8TDY3
GIVMDSGDGVTHIVP

ACTBL2

151

Q562R1
HLETFAMEGLKGGPE

CCDC171

1181

Q6TFL3
MHGDTEGTVPGNALV

EHD2

101

Q9NZN4
MLELDSSGHLDGPGG

GSDMC

361

Q9BYG8
PSFIGMESAGIHETT

ACTA2

266

P62736
MDVSSEHTKDPGGEG

CCDC96

1

Q2M329
VLVSSGGPEGHYEML

C1QL1

11

O75973
GPTAGAAISSHMDID

ALDH1A1

226

P00352
GGIVMDHSDNPLGAA

ADAM12

331

O43184
GPESIAHIGDVMFTG

APMAP

101

Q9HDC9
PGVEAFHVDMDSGLV

CDH23

2551

Q9H251
TVMSPCGGEDIVADH

HLA-DQA1

16

P01909
MHTGEPLFSGSNEVD

DYRK1B

306

Q9Y463
QGPGVTHIVVDEGMD

POLL

76

Q9UGP5
FAVQSHGVDMDGPFG

IGDCC4

821

Q8TDY8
HGVDMDGPFGSVVER

IGDCC4

826

Q8TDY8
VDFPTSGVAGGDMET

MUC5B

1796

Q9HC84
GLANVPTSHFVGMDG

PCDHGA7

731

Q9Y5G6
MFLGTGEPALDTGDD

IQCE

1

Q6IPM2
GGLSPAGDMSHVDAA

OFD1

841

O75665
GGLAGMPTSHFVGVD

PCDHGA11

731

Q9Y5H2
AASEPVAEGMDGGPH

ZFYVE28

536

Q9HCC9
VAEGMDGGPHKLSTG

ZFYVE28

541

Q9HCC9
SHLGASQLTPMGEGD

NOS2

646

P35228
GLVGDGPVDMRTSHS

GATAD2A

76

Q86YP4
MESGLTFHEVDSPQG

MMP25

151

Q9NPA2
GFTGEDEDMAFPGHL

NPHS1

1161

O60500
GLASMPGSHFVGVEG

PCDHGA6

731

Q9Y5G7
GVHLEMMSPGGEGDL

FAM171A1

396

Q5VUB5
SMEAAGIPVSFGGHR

HDAC4

611

P56524
IEGMEFGPGELDSVG

MXD4

161

Q14582
GAGSVTPERMEGNHL

MBTPS1

891

Q14703
AGSAEEGVMTPELAG

GNAI3

111

P08754
MPGAHVFSGGVLDAA

NUDT19

56

A8MXV4
TMVGFGPEDDHFVAE

GLOD4

71

Q9HC38
GRLGHGSSEDEAIPM

HERC2

581

O95714
HGGGDPTAATDMGAL

ESPN

126

B1AK53
FVESAESDHMAIPGG

MCM3AP

366

O60318
TGVLHMASFGEGEQE

HERC1

1856

Q15751
VVGEPTLMGGEFGDE

LDB2

301

O43679
THAAFIAMAGPEGLG

BSN

2506

Q9UPA5
AGISEMFEGHQGPIT

DYNC1I2

466

Q13409
MSHQEGSTDGLPDLG

DCAF8L2

1

P0C7V8
PGEVTFVAGEGLHMH

CCNYL2

51

Q5T2Q4
TPEGEFVSMGVISDG

MDH1

261

P40925
ETVHLFMEAGEGGSV

MAP3K8

201

P41279
VEEHAAMDGSEGVPG

LTK

186

P29376
AAGTFIDGHFVEMPA

KIAA0232

461

Q92628
MPDDGGTAHLSVVAE

GGTLC1

31

Q9BX51
FGGKFCSEEEHPMEG

NRXN2

236

Q9P2S2
SELAEAFGEPHSQMG

KANK1

846

Q14678
NESMDHGGVGPYELG

RPS6KB1

51

P23443
GVFMFTSESVGEGHP

MAT1A

16

Q00266
TEEGGLHVHMEFPGA

LCN15

66

Q6UWW0
SEPLELMVSGHSGGS

LILRA6

411

Q6PI73
EAEGAVGALPGMITF

POLE

2036

Q07864
GGVDFHMKAVPGTEV

NOL8

121

Q76FK4
DGPMIVHDEHGGVTA

PTPRZ1

2216

P23471
FGDTGEGWETVEMHP

NUCB1

326

Q02818
MGGKVPVSEGLEHSD

HUWE1

1176

Q7Z6Z7
DDGTFMIPGEKVAHT

HSH2D

86

Q96JZ2
EEPHFDGIMDGFSGK

MYOCD

831

Q8IZQ8
QPGFTVSGMLEHGGL

POU3F4

136

P49335
GGTMETDDHMGGIPA

PIPSL

321

A2A3N6
IPEGEGASEQGMARH

PNCK

316

Q6P2M8
AQFHPDGLIFGTGTM

PRPF19

356

Q9UMS4
HVGFDAVTGEFTGMP

PAK1

86

Q13153
VGFDAVTGEFTGMPE

PAK2

86

Q13177
FHEGSAEDGPRVVFM

ASPHD2

331

Q6ICH7
AAMHEPDGVAGVSAI

ATR

1681

Q13535
GVDQGSATGAVHLMP

ATMIN

331

O43313
VMSGIHPAEDTEGTE

CENPF

2961

P49454
IHPEFCDEMDAGGLG

CHAMP1

36

Q96JM3
ENVTTLGGSGADHMP

CEP126

696

Q9P2H0
MEDDFPGGVIGKIHA

FAT3

3561

Q8TDW7
HTAGPTFPEEMGETQ

BCL6

491

P41182
ISSGHNMVEGEGAPK

FBXO40

251

Q9UH90
QPDGSFLMHVGGEVD

FNTB

186

P49356
GSMAPGHVADFLVAD

KHK

61

P50053
LGMTVEGPEGSEREH

FAM102A

271

Q5T9C2
MGGPETLGDVHDFLL

FECH

76

P22830
GIVGMEVDGLPFHNT

DGLUCY

586

Q7Z3D6
GDVPVIAMETFGAHS

SDS

186

P20132
MSHGGPFTEEKVEDV

SLC15A4

301

Q8N697
MGLDGATYDLEGHPQ

C4A

1686

P0C0L4
LEEGSFHPLGMSGAG

IHH

396

Q14623
GCPGMATFREDTGVH

PRR14L

1771

Q5THK1
MEHSEGAPGDPAGTV

SLC51B

1

Q86UW2
HIYEDGIPGTEAMNG

PDCL

186

Q13371
GEHSTAGEMGPLLGA

NAP1L6P

6

A6NFF2
GLASMPGSHFVGVDG

PCDHGA1

731

Q9Y5H4
DSHGEEGEPSSIMNV

MINK1

331

Q8N4C8
ESGGSVEAPRMGFTH

RPH3AL

241

Q9UNE2
LDLPDGGHLTHGFMT

SHMT1

141

P34896
IMEELLGSHPGDTGE

NUTM2F

401

A1L443
IMEELLGSHPGDTGE

NUTM2G

386

Q5VZR2
TGAGGVMEPHAVYSG

FOXF1

251

Q12946
MSEGDSVGESVHGKP

RER1

1

O15258
VFMHVDEPGDTGFGT

SORT1

361

Q99523
DHFDIEIMGGLGPST

AGXT

341

P21549
MASGVGAAFEELPHD

TRIM44

1

Q96DX7
MAAPLSVEVEFGGGA

URM1

1

Q9BTM9
VIGDSVHMEGLPGSS

SYNM

1291

O15061
TGETPIAVMGEFGDL

RFX3

646

P48380
VAEADEGGPSAITGM

ING1

16

Q9UK53
NGVLVMHPAGGFSED

PELI3

236

Q8N2H9
MHPAGGFSEDSAPGV

PELI3

241

Q8N2H9
MHGGLFSEDGVTLDD

PPP5C

351

P53041
PGTPMNAGAEEVHSD

NCAN

996

O14594
SGDGEMLPGVSRLHT

PIK3R6

401

Q5UE93
VIDLPGGGAAFVMEH

FN3K

76

Q9H479
APEMGEELLGSEGIH

RNF169

456

Q8NCN4
GHGVLGSDVFEEPMS

SUPT7L

356

O94864
PDSGHETMVGSGLSQ

KDF1

331

Q8NAX2
TTHNGGEMTEESEGP

SANBR

131

Q6NSI8
GTPVLSVVDMHTGGE

L3HYPDH

16

Q96EM0
IHFGPGESSSEDAVM

BIRC2

376

Q13490
PSFIGMESAGIHETT

ACTC1

266

P68032
TGPDIHHFIMGSEGT

AGPS

356

O00116
EGVGGPADYHALGAM

CHST2

381

Q9Y4C5
FGDDIPGMEGLGTDI

PDE6H

46

Q13956
HSGTFGGILHEPMAD

CNDP1

261

Q96KN2
FVHVDMSEGVPGDPA

TJAP1

261

Q5JTD0
MEGSEPVAAHQGEEA

UBA6

1

A0AVT1
NATGPDLEFSMHDGT

WDR47

696

O94967
GLFPAVGMHSLGEEV

SPRYD3

181

Q8NCJ5
QATSEDMHGFEAPGT

SPATA31A1

971

Q5TZJ5
GVEGKAGMAAVADPH

SLC27A1

546

Q6PCB7
SAHITEQLGMAPGGE

TRABD

156

Q9H4I3
VFSLAGPVVSMAGHG

WDHD1

566

O75717
GAEPTTSEFTVLMHG

SRL

126

Q86TD4
RDDGMEEVVGHTQGP

TNS1

346

Q9HBL0
SSGDDGEMPAMHEIG

SLC4A5

471

Q9BY07
GTEEHVMAAFGPSLE

POLR3B

256

Q9NW08
GLSEMQEGHFRPGID

ZNF264

131

O43296
GVDIVMDPLGGSDTA

VAT1

256

Q99536
QHPELGVGMTTEGFD

TTC30A

221

Q86WT1
VTMFLDGGGIAEEPS

UBXN7

46

O94888
RPHEDVFIMDTIGGG

STRN4

381

Q9NRL3
GDSHLGETIPMASRG

TGM1

801

P22735
GSMEGHGMDESLSPG

ZNF407

1946

Q9C0G0
HGMDESLSPGGAVIQ

ZNF407

1951

Q9C0G0
EDGIGMAHTEHVPGT

TRIM23

266

P36406
LDFGGPEGELTMDLH

SNTB2

501

Q13425
METTHGAPLDSVGSD

PPP6R3

691

Q5H9R7
EAMEEQGAAHGPLGF

XRCC3

261

O43542