Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

3.79e-284313622GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

2.68e-218843622GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

2.46e-1713533622GO:0004888
GeneOntologyMolecularFunctionodorant binding

OR2A25 OR2A7 OR5M9 OR12D2 OR12D1 OR2A4 OR13A1 OR5H6

5.58e-11127368GO:0005549
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

7.81e-294323522GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

4.02e-284653522GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

1.02e-274853522GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

5.69e-275243522GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

1.47e-265473522GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

5.78e-265823522GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

6.57e-247223522GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

3.51e-2010723522GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR12D1 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

9.85e-1813953522GO:0007186
GeneOntologyCellularComponentmitotic spindle midzone

OR2A7 OR2A4

3.41e-0416362GO:1990023
GeneOntologyCellularComponentvacuolar membrane

VAC14 ATP6V0A1 WDFY3 ABCA5 GAA

1.67e-03507365GO:0005774
GeneOntologyCellularComponentFlemming body

OR2A7 OR2A4

1.75e-0336362GO:0090543
GeneOntologyCellularComponentspindle midzone

OR2A7 OR2A4

2.16e-0340362GO:0051233
GeneOntologyCellularComponentmitotic spindle pole

OR2A7 OR2A4

2.49e-0343362GO:0097431
MousePhenoabnormal vacuole morphology

VAC14 ATP6V0A1 GAA

2.78e-0566133MP:0020851
DomainOlfact_rcpt

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

5.77e-203932916IPR000725
DomainGPCR_Rhodpsn_7TM

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

2.77e-166702916IPR017452
Domain7tm_1

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

3.27e-166772916PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

3.93e-166852916PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

4.51e-166912916PS50262
DomainGPCR_Rhodpsn

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

4.61e-166922916IPR000276
Domain-

RELCH VAC14 WDFY3

4.82e-032222931.25.10.10
DomainHEAT_REPEAT

RELCH VAC14

5.27e-0370292PS50077
DomainARM-like

RELCH VAC14 WDFY3

8.27e-03270293IPR011989
Domain-

WDFY3 LAMA1

9.51e-03952922.60.120.200
DomainARM-type_fold

RELCH VAC14 WDFY3

1.53e-02339293IPR016024
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

2.40e-224173019M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR52E1 OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

7.14e-196363019M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2C3 OR3A1 OR4Q3 OR2A25 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6

8.52e-183893016M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4Q3 OR10H5 OR10H2 OR10H1

1.39e-0570304MM14984
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR3A1 OR2S2 OR10H2 OR10H1 OR2A4

2.01e-04260305M39397
PathwayREACTOME_SENSORY_PERCEPTION

OR4Q3 OR10H5 OR10H2 OR10H1

6.66e-04190304MM15687
PathwayWP_GPCRS_OTHER

OR3A1 OR2A7 OR2A4

1.09e-0396303MM15939
Pubmed

The human olfactory receptor gene family.

OR2C3 OR3A1 OR4Q3 OR2S2 OR2A7 OR10H5 OR5M9 OR12D2 OR4Q2 OR4K3 OR10H2 OR10H1 OR2A4 OR4K14 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

2.17e-25541361914983052
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR3A1 OR4Q3 OR2A25 OR2A7 OR5M9 OR12D2 OR12D1 OR10H1 OR2A4 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

1.74e-19340361411802173
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR3A1 OR4Q3 OR2A25 OR2A7 OR5M9 OR12D2 OR12D1 OR10H1 OR2A4 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

1.74e-19340361411875048
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR3A1 OR4Q3 OR2A25 OR2A7 OR5M9 OR12D2 OR12D1 OR10H1 OR2A4 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

1.97e-19343361432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR3A1 OR4Q3 OR2A25 OR2A7 OR5M9 OR12D2 OR12D1 OR10H1 OR2A4 OR10AD1 OR13A1 OR5H6 OR2W6P OR10D4P

2.23e-19346361414611657
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR2C3 OR2S2 OR2A7 OR10H5 OR5M9 OR4Q2 OR4K3 OR10H2 OR10H1 OR4K14 OR10AD1

2.51e-16219361112213199
Pubmed

Personal receptor repertoires: olfaction as a model.

OR52E1 OR2S2 OR12D2 OR12D1 OR5H6

4.36e-103836522908908
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5M9 OR12D2 OR12D1 OR10D4P

1.06e-067436415081110
Pubmed

Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.

OR2A7 OR2A4

3.12e-06336227315375
Pubmed

A zonal organization of odorant receptor gene expression in the olfactory epithelium.

OR2A7 OR2A4

6.24e-0643627683976
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR2S2 OR12D2 OR5H6

6.52e-063536316939646
Pubmed

Different noses for different people.

OR4Q2 OR4K3

2.91e-05836212730696
Pubmed

Saturation mutagenesis defines novel mouse models of severe spine deformity.

OR2A7 OR2A4

2.91e-05836234142127
Pubmed

Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.

OR12D2 OR12D1

8.07e-051336214506126
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR2A7 OR2A4

8.07e-051336211014824
Pubmed

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.

OR2A7 OR2A4

9.41e-05143627528109
Cytoband6p22.2-p21.31

OR12D2 OR12D1

5.97e-0653626p22.2-p21.31
Cytoband14q11.2

OR4Q3 OR4Q2 OR4K3 OR4K14

1.22e-0518036414q11.2
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR4Q3 OR4Q2 OR4K3 OR4K14

1.32e-04332364chr14q11
Cytoband19p13.1

OR10H2 OR10H1

6.59e-044836219p13.1
Cytoband7q35

OR2A25 OR2A7

8.65e-04553627q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

OR2A25 OR2A7

1.24e-0366362chr7q35
CytobandEnsembl 112 genes in cytogenetic band chr6p22

OR12D2 OR12D1 OR2W6P

3.23e-03378363chr6p22
GeneFamilyOlfactory receptors, family 2

OR2C3 OR2A25 OR2S2 OR2A7 OR2A4 OR2W6P

2.74e-08113306149
GeneFamilyOlfactory receptors, family 10

OR10H5 OR10H2 OR10H1 OR10AD1 OR10D4P

7.38e-0866305157
GeneFamilyOlfactory receptors, family 12

OR12D2 OR12D1

7.98e-063302160
GeneFamilyOlfactory receptors, family 4

OR4Q3 OR4Q2 OR4K3 OR4K14

5.87e-05129304151
GeneFamilyOlfactory receptors, family 5

OR5M9 OR5H6

1.48e-02112302152
CoexpressionAtlaskidney_P0_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000

OR10H5 OR10H2

4.46e-0512182gudmap_kidney_P0_CapMes_Crym_k1_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000

OR10H5 OR10H2

9.16e-0517182gudmap_kidney_P4_CapMesRenVes_Crym_k2_1000
Diseasemalaria

VAC14 PIGZ

3.64e-03102262EFO_0001068
DiseaseColorectal Carcinoma

RELCH ABCA5 LAMA1

2.32e-02702263C0009402

Protein segments in the cluster

PeptideGeneStartEntry
LILMLGSLLAFHYGL

ABCA5

1081

Q8WWZ7
LFLLLGPSSANMDYH

SLC4A2

556

P04920
HMYLSALQSLIPSLF

RELCH

746

Q9P260
MNTTLFHPYSFLLLG

OR52E1

1

Q8NGJ3
GFSAFPHLQLMLFLL

OR10H5

16

Q8NGA6
GFSAFPHLQLMLFLL

OR10H2

16

O60403
LNSPMYFFLGHLSLL

OR10AD1

56

Q8NGE0
TRLHTPMYFFLGNLS

OR10D4P

51

Q8NGN7
LHTPMYFFLANLSFL

OR2W6P

61

Q8NHA6
PKLHTPMYFFLGNLS

OR3A1

56

P47881
HSPMYFLLGNLSFID

OR4K3

56

Q96R72
HSSPMYFLLGNLAFL

OR4K14

56

Q8NGD5
NSSPMYFLLGNLSFL

OR4Q2

56

P0C623
LQSPMYYFLGHLSFI

OR4Q3

56

Q8NH05
HPFYNLLKMLSFPLL

FMO6P

516

O60774
KYLLLFHSLFNPMLN

OR2A7

271

Q96R45
PRLHSLMYFFLGNLS

OR12D2

51

P58182
LHTPMYFFLGNLSFL

OR2S2

56

Q9NQN1
LHTPMYFFLANLPFL

OR2C3

56

Q8N628
KYLLLFHSLFNPMLN

OR2A4

271

O95047
PRLHSPMYFFLGNLS

OR12D1

51

P0DN82
LHIPMYLFLGSLAFV

OR5H6

71

Q8NGV6
LGLVKLPLHQFYMSF

C2CD3

896

Q4AC94
MHYPTALLFLILANG

DNASE1L1

1

P49184
AFYPFMRNHNSLLSL

GAA

666

P10253
GFSVFPHLQLMLFLL

OR10H1

16

Q9Y4A9
KYLLLFHSLFNPMLN

OR2A25

271

A4D2G3
FHSLFNPMLNPLIYS

OR2A25

276

A4D2G3
PGLHAPMYFFLLNLA

OR13A1

71

Q8NGR1
ALYGLLMLLPQSSAF

VAC14

696

Q08AM6
PQHGLYMLFLLVLVF

RELL2

11

Q8NC24
MLFNTFSPNGLLLYL

LAMA1

2331

P25391
PQLQSPMYFFLSHLS

OR5M9

51

Q8NGP3
HTNVPALYFLLMALF

WDFY3

1766

Q8IZQ1
LLLYFMPLALLSAFS

PIGZ

371

Q86VD9
PSLLIHFINMFLFSY

ATP6V0A1

606

Q93050
GFMLLFFQYLHPLRS

XKRX

396

Q6PP77