Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

UBTFL6 UBTFL1

1.93e-049472GO:0001181
GeneOntologyMolecularFunctionRNA polymerase I core promoter sequence-specific DNA binding

UBTFL6 UBTFL1

2.94e-0411472GO:0001164
GeneOntologyMolecularFunctionRNA polymerase I transcription regulatory region sequence-specific DNA binding

UBTFL6 UBTFL1

4.16e-0413472GO:0001163
GeneOntologyMolecularFunctiongeneral transcription initiation factor activity

UBTFL6 BRF1 UBTFL1

5.50e-0468473GO:0140223
GeneOntologyMolecularFunctiontransmembrane transporter binding

AKAP6 PDE4D ANK1 ANK2

7.10e-04172474GO:0044325
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK1 ANK2

1.45e-0324472GO:0008093
GeneOntologyMolecularFunctionhistone reader activity

PHF14 MSL3

1.70e-0326472GO:0140566
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

MYT1L RLF PHOX2A LHX4 CSRNP2 LMX1A

1.92e-03560476GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

MYT1L RLF PHOX2A LHX4 CSRNP2 LMX1A

2.02e-03566476GO:0001216
GeneOntologyMolecularFunctionATPase binding

PDE4D ANK1 ANK2

2.10e-03108473GO:0051117
GeneOntologyBiologicalProcessaxon extension

AUTS2 CLASP2 MAP3K13 ULK1 SHTN1

1.37e-05135475GO:0048675
GeneOntologyBiologicalProcessgrowth

AKAP6 ANKRD11 AUTS2 CLASP2 UBTFL6 MAP3K13 PDE4D ULK1 EAF2 SHTN1 LMX1A UBTFL1

1.49e-0512354712GO:0040007
GeneOntologyBiologicalProcessdevelopmental growth

AKAP6 ANKRD11 AUTS2 CLASP2 UBTFL6 MAP3K13 PDE4D ULK1 SHTN1 UBTFL1

3.14e-059114710GO:0048589
GeneOntologyBiologicalProcessaxonogenesis

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

3.75e-05566478GO:0007409
GeneOntologyBiologicalProcesssomatic motor neuron differentiation

PHOX2A LHX4

5.06e-055472GO:0021523
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

AKAP6 PDE4D ANK2

5.77e-0533473GO:0010880
GeneOntologyBiologicalProcessdevelopmental cell growth

AKAP6 AUTS2 CLASP2 MAP3K13 ULK1 SHTN1

5.97e-05301476GO:0048588
GeneOntologyBiologicalProcesscell growth

AKAP6 AUTS2 CLASP2 MAP3K13 ULK1 EAF2 SHTN1 LMX1A

7.52e-05625478GO:0016049
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

AKAP6 PDE4D ANK2

8.16e-0537473GO:0014808
GeneOntologyBiologicalProcessaxon development

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

9.07e-05642478GO:0061564
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

AKAP6 PDE4D ANK2

9.57e-0539473GO:1903514
GeneOntologyBiologicalProcessneuron projection extension

AUTS2 CLASP2 MAP3K13 ULK1 SHTN1

1.06e-04207475GO:1990138
GeneOntologyBiologicalProcessregulation of cardiac muscle cell contraction

AKAP6 PDE4D ANK2

1.28e-0443473GO:0086004
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

AKAP6 PDE4D ANK2

1.38e-0444473GO:0070296
GeneOntologyBiologicalProcessregulation of cell growth

AKAP6 CLASP2 MAP3K13 ULK1 EAF2 SHTN1 LMX1A

1.61e-04519477GO:0001558
GeneOntologyBiologicalProcessregulation of extent of cell growth

CLASP2 MAP3K13 ULK1 SHTN1

1.71e-04122474GO:0061387
GeneOntologyBiologicalProcessregulation of relaxation of cardiac muscle

AKAP6 PDE4D

1.81e-049472GO:1901897
GeneOntologyBiologicalProcessactin-mediated cell contraction

AKAP6 PDE4D ANK2 SHTN1

1.99e-04127474GO:0070252
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MYT1L RLF AUTS2 PHOX2A ASXL2 LHX4 CSRNP2 EAF2 ARID4A LMX1A PPP1R12A

2.28e-0413904711GO:0045944
GeneOntologyBiologicalProcessregulation of actin filament-based movement

AKAP6 PDE4D ANK2

2.40e-0453473GO:1903115
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

2.59e-04748478GO:0048667
GeneOntologyBiologicalProcessRNA polymerase I preinitiation complex assembly

UBTFL6 UBTFL1

2.76e-0411472GO:0001188
GeneOntologyBiologicalProcessprotein-DNA complex organization

RLF PHF14 CHD1 UBTFL6 BRF1 ARID4A UBTFL1 BANP MSL3

3.66e-04999479GO:0071824
GeneOntologyBiologicalProcessactin filament-based movement

AKAP6 PDE4D ANK2 SHTN1

4.05e-04153474GO:0030048
GeneOntologyBiologicalProcessneuron projection morphogenesis

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

4.13e-04802478GO:0048812
GeneOntologyBiologicalProcesscellular response to epinephrine stimulus

AKAP6 PDE4D

4.54e-0414472GO:0071872
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

4.75e-04819478GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

AUTS2 CLASP2 MAP3K13 ULK1 NRXN3 LHX4 SHTN1 LMX1A

5.02e-04826478GO:0048858
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

AUTS2 CLASP2 MAP3K13 ULK1 SHTN1

5.77e-04299475GO:0060560
GeneOntologyBiologicalProcessresponse to epinephrine

AKAP6 PDE4D

6.76e-0417472GO:0071871
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase I promoter

UBTFL6 UBTFL1

7.60e-0418472GO:0006361
GeneOntologyBiologicalProcessregulation of relaxation of muscle

AKAP6 PDE4D

8.48e-0419472GO:1901077
GeneOntologyBiologicalProcesspositive regulation of potassium ion transmembrane transporter activity

AKAP6 ANK2

9.41e-0420472GO:1901018
GeneOntologyBiologicalProcesstranscription preinitiation complex assembly

UBTFL6 BRF1 UBTFL1

9.61e-0485473GO:0070897
GeneOntologyBiologicalProcessrelaxation of cardiac muscle

AKAP6 PDE4D

1.04e-0321472GO:0055119
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

AKAP6 PDE4D ANK2

1.10e-0389473GO:0055117
GeneOntologyBiologicalProcesscardiac muscle cell contraction

AKAP6 PDE4D ANK2

1.25e-0393473GO:0086003
GeneOntologyBiologicalProcessvocalization behavior

AUTS2 NRXN3

1.36e-0324472GO:0071625
GeneOntologyCellularComponentchromatin

MYT1L ANKRD11 ANKRD31 GON4L PHF14 CHD1 PHOX2A LHX4 CSRNP2 ARID4A LMX1A AFF4 MSL3

1.19e-0514804613GO:0000785
GeneOntologyCellularComponentsuper elongation complex

EAF2 AFF4

7.07e-056462GO:0032783
GeneOntologyCellularComponentA band

ANK1 ANK2 PPP1R12A

2.04e-0452463GO:0031672
GeneOntologyCellularComponentfibrillar center

GON4L DCLRE1A COIL AFF4

3.82e-04156464GO:0001650
GeneOntologyCellularComponentkinetochore

CLASP2 SGO1 PPP1R12A KNL1

6.68e-04181464GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

CLASP2 SGO1 PPP1R12A KNL1

8.49e-04193464GO:0000779
HumanPhenoAbnormality of the palpebral fissures

MYT1L ANKRD11 AUTS2 CHD1 PDE4D BRF1 ANK1 PPP1R12A AFF4 KNL1 MSL3

1.73e-058801711HP:0008050
HumanPhenoAbnormal cheek morphology

MYT1L ANKRD11 AUTS2 BRF1 ANK1 AFF4 MSL3

1.78e-05282177HP:0004426
HumanPhenoAbnormal midface morphology

MYT1L ANKRD11 AUTS2 CHD1 PDE4D BRF1 LHX4 ANK1 AFF4 MSL3

1.86e-057041710HP:0000309
HumanPhenoAbnormal eyelid morphology

MYT1L ANKRD11 AUTS2 CHD1 PHOX2A ASXL2 PDE4D BRF1 ANK1 PPP1R12A AFF4 KNL1 MSL3

3.88e-0514081713HP:0000492
HumanPhenoAbnormal upper lip morphology

MYT1L ANKRD11 AUTS2 ASXL2 PDE4D BRF1 LHX4 PPP1R12A AFF4 KNL1 MSL3

5.01e-059801711HP:0000177
HumanPhenoAbnormal periauricular region morphology

ANKRD11 AUTS2 BRF1 ANK1 MSL3

5.03e-05131175HP:0000383
HumanPhenoMild fetal ventriculomegaly

MYT1L ASXL2

1.04e-045172HP:0010952
HumanPhenoThick eyebrow

ANKRD11 AUTS2 CHD1 AFF4 KNL1

1.09e-04154175HP:0000574
HumanPhenoAplasia/hypoplasia involving bones of the hand

ANKRD11 PHOX2A ASXL2 PDE4D BRF1 LHX4 AFF4 MSL3

1.50e-04538178HP:0005927
HumanPhenoAbnormal fetal central nervous system morphology

MYT1L ASXL2

1.56e-046172HP:0034206
HumanPhenoAplasia/hypoplasia involving the skeleton

ANKRD11 AUTS2 PHOX2A ASXL2 PDE4D BRF1 LHX4 ANK1 PPP1R12A AFF4 KNL1 MSL3

1.70e-0413431712HP:0009115
HumanPhenoAbnormal external nose morphology

MYT1L ANKRD11 AUTS2 ASXL2 PDE4D BRF1 LHX4 AFF4 KNL1 MSL3

1.93e-049161710HP:0010938
HumanPhenoAplasia/hypoplasia involving bones of the upper limbs

ANKRD11 PHOX2A ASXL2 PDE4D BRF1 LHX4 AFF4 MSL3

2.32e-04572178HP:0006496
HumanPhenoCryptorchidism

MYT1L ANKRD11 AUTS2 PDE4D BRF1 LHX4 ANK1 PPP1R12A AFF4

3.37e-04780179HP:0000028
HumanPhenoAbnormality of upper lip vermillion

MYT1L ANKRD11 ASXL2 PDE4D AFF4 KNL1 MSL3

4.30e-04464177HP:0011339
HumanPhenoAbnormal lip morphology

MYT1L ANKRD11 AUTS2 ASXL2 PDE4D BRF1 LHX4 PPP1R12A AFF4 KNL1 MSL3

5.10e-0412491711HP:0000159
DomainAnk_2

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

1.22e-05215456PF12796
DomainAnk

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

1.70e-05228456PF00023
Domain-

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

2.72e-052484561.25.40.20
DomainANK

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

2.91e-05251456SM00248
DomainANK_REPEAT

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

3.05e-05253456PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

3.11e-05254456IPR020683
DomainANK_REP_REGION

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

3.11e-05254456PS50297
DomainAnkyrin_rpt

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

3.70e-05262456IPR002110
DomainChromodomain-like

CHD1 ARID4A MSL3

6.17e-0532453IPR016197
DomainCHROMO

CHD1 ARID4A MSL3

6.78e-0533453SM00298
DomainChromo/shadow_dom

CHD1 ARID4A MSL3

6.78e-0533453IPR000953
DomainTudor-knot

ARID4A MSL3

8.46e-056452IPR025995
DomainTudor-knot

ARID4A MSL3

8.46e-056452PF11717
DomainZU5

ANK1 ANK2

2.02e-049452SM00218
DomainZU5

ANK1 ANK2

2.52e-0410452PS51145
DomainZU5_dom

ANK1 ANK2

3.69e-0412452IPR000906
DomainZU5

ANK1 ANK2

3.69e-0412452PF00791
DomainDEATH

ANK1 ANK2

1.92e-0327452SM00005
DomainCHROMO_2

CHD1 MSL3

2.06e-0328452PS50013
DomainCHROMO_1

CHD1 MSL3

2.06e-0328452PS00598
DomainDeath

ANK1 ANK2

2.86e-0333452PF00531
DomainDeath_domain

ANK1 ANK2

3.78e-0338452IPR000488
DomainDEATH_DOMAIN

ANK1 ANK2

3.78e-0338452PS50017
Domain-

GON4L PHOX2A LHX4 LMX1A

4.72e-032834541.10.10.60
Pubmed

CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.

CHD1 UBTFL6 UBTFL1

2.31e-09347326092847
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ANKRD11 OTUD4 GON4L CASC3 RRP15 PHF14 CHD1 CLASP2 GPBP1L1 DROSHA PPP1R12A AFF4

4.98e-071497471231527615
Pubmed

Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice.

ANK1 ANK2

1.79e-0624728471772
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RLF GON4L RIOK1 SGO1 SHTN1 ARID4A PPP1R12A MSL3

2.23e-0664547825281560
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RLF ANKRD11 AUTS2 CASC3 PHF14 CLASP2 PDE4D SHTN1 PPP1R12A AFF4 BANP

3.59e-061489471128611215
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

CHD1 RIOK1 FAM193A ANK2 COIL SHTN1 PPP1R12A AFF4 KNL1

3.81e-0693447933916271
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK1 ANK2

5.36e-06347233410423
Pubmed

Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP).

AKAP6 PDE4D

5.36e-06347223806656
Pubmed

cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.

AKAP6 PDE4D

5.36e-06347220106966
Pubmed

AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.

ULK1 AFF4

5.36e-06347237731335
Pubmed

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

ANK1 ANK2

5.36e-06347212527750
Pubmed

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.

ANK1 ANK2

5.36e-06347221177872
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK1 ANK2

5.36e-06347234289389
Pubmed

MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth.

ANK1 ANK2

5.36e-06347216597699
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CASC3 DCLRE1A CHD1 CLASP2 RIOK1 FAM193A KNL1 BANP

5.70e-0673347834672954
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ANKRD11 RRP15 PHF14 DCLRE1A NKTR ASXL2 COIL ARID4A BANP MSL3

7.24e-061294471030804502
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

OTUD4 CASC3 CLASP2 RIOK1 GPBP1L1 EAF2 COIL DROSHA NFKBIB

8.92e-06103847926673895
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

RLF ANKRD11 PHF14 CHD1 CLASP2 NKTR FAM193A BRF1 COIL ARID4A

9.02e-061327471032694731
Pubmed

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

AKAP6 PDE4D

1.07e-05447216177794
Pubmed

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module.

AKAP6 PDE4D

1.07e-05447211296225
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

OTUD4 CASC3 RRP15 CLASP2 NKTR RIOK1 ANK2 COIL DROSHA AFF4

1.20e-051371471036244648
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RLF RRP15 PHF14 CHD1 SGO1 ARID4A AFF4

1.65e-0560847736089195
Pubmed

Human transcription factor protein interaction networks.

RLF AUTS2 OTUD4 GON4L RRP15 ASXL2 LHX4 ARID4A NFKBIB BANP

1.71e-051429471035140242
Pubmed

Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations.

CHD1 PPP1R12A

1.78e-05547231883643
Pubmed

Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice.

ANK1 ANK2

2.67e-0564721716634
Pubmed

Involvement of a novel preimplantation-specific gene encoding the high mobility group box protein Hmgpi in early embryonic development.

UBTFL6 UBTFL1

2.67e-05647219915186
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

AUTS2 CHD1 NKTR MAP3K13 ULK1 PPP1R12A AFF4 KNL1

2.71e-0591047836736316
Pubmed

Associations of human erythrocyte band 4.2. Binding to ankyrin and to the cytoplasmic domain of band 3.

ANK1 ANK2

3.74e-0574722968981
Pubmed

Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.

ANK1 ANK2

3.74e-0574727495297
Pubmed

A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis.

ULK1 ANK1

3.74e-05747227742708
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ANKRD11 RRP15 PHF14 CHD1 COIL ARID4A AFF4 KNL1

3.79e-0595447836373674
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

RLF GON4L PHF14 ARID4A

5.13e-0515047428242625
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

MYT1L AKAP6 BRF1 ANK2

5.27e-0515147417043677
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK1 ANK2

7.99e-051047222159418
Pubmed

The modular nature of apoptotic signaling proteins.

ANK1 ANK2

7.99e-051047210442092
Pubmed

The little elongation complex regulates small nuclear RNA transcription.

EAF2 AFF4

1.17e-041247222195968
Pubmed

LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus.

PHOX2A LHX4

1.17e-041247218031722
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

FNIP2 CLASP2 EAF2 ARID4A

1.18e-0418647433637726
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

GPBP1L1 BRF1 SGO1 DROSHA KNL1 BANP

1.36e-0458847638580884
Pubmed

Loss of the tumor suppressor BAP1 causes myeloid transformation.

OTUD4 ASXL2

1.38e-041347222878500
Pubmed

Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function.

PHOX2A LMX1A

1.38e-041347224733890
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CLASP2 ASXL2 PDE4D COIL SGO1 PPP1R12A KNL1 MSL3

1.44e-04115547820360068
Pubmed

Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes.

SGO1 KNL1

1.61e-041447220231385
Pubmed

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.

FNIP2 ULK1

1.61e-041447225126726
Pubmed

Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons.

PHOX2A LMX1A

2.12e-041647220493948
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 OTUD4 GON4L ASXL2 ULK1

2.19e-0440747512693553
Pubmed

ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons.

PHOX2A LHX4

2.70e-041847227819291
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

OTUD4 CASC3 CLASP2 ANK2 SHTN1 PPP1R12A AFF4

2.92e-0496347728671696
Pubmed

beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region.

PHOX2A LMX1A

3.34e-042047220532162
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PHF14 ULK1 NRXN3

3.51e-041014739872452
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

GON4L SHTN1 KNL1

3.51e-0410147310997877
Pubmed

A refined map of early gene expression in the dorsal rhombomere 1 of mouse embryos.

PHOX2A LMX1A

3.69e-042147220206242
Pubmed

Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.

PHOX2A LMX1A

4.44e-042347235700056
Pubmed

LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth.

LHX4 LMX1A

5.26e-042547219304889
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 GON4L CLASP2 ANK2 DROSHA

5.46e-0449747523414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ANKRD11 CLASP2 RIOK1 ANK1 PPP1R12A

5.46e-0449747536774506
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

OTUD4 CLASP2 RIOK1

5.67e-0411947335776542
Pubmed

Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development.

PHOX2A LMX1A

5.69e-042647221752929
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

OTUD4 RRP15 PHF14 COIL ARID4A MSL3

5.88e-0477447615302935
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L AKAP6 OTUD4 CLASP2 ASXL2 PPP1R12A AFF4

5.93e-04108447711544199
Pubmed

Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.

PHOX2A LMX1A

6.14e-042747221925604
Pubmed

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.

PHOX2A LMX1A

8.11e-043147219592574
Pubmed

Proximity labeling reveals dynamic changes in the SQSTM1 protein network.

AUTS2 OTUD4 GPBP1L1 FAM193A

9.40e-0432247439098523
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

AKAP6 ANK2 DROSHA PPP1R12A

1.02e-0332947417474147
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

PHF14 CHD1 NKTR COIL

1.03e-0333047433301849
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

CLASP2 ANK2

1.16e-033747227565344
Pubmed

Functional proteomics mapping of a human signaling pathway.

RLF ASXL2 CSRNP2 DROSHA KNL1

1.19e-0359147515231748
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

RIOK1 FAM193A

1.22e-033847236674791
Pubmed

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

OTUD4 CLASP2 RIOK1

1.24e-0315647326170170
Pubmed

Interaction network of human early embryonic transcription factors.

RLF AUTS2 ASXL2 ARID4A

1.29e-0335147438297188
InteractionNUP43 interactions

RLF ANKRD11 GON4L RRP15 CHD1 NKTR ASXL2 COIL SGO1 ARID4A PPP1R12A KNL1

1.38e-086254712int:NUP43
InteractionH2BC8 interactions

RLF GON4L RRP15 PHF14 CHD1 RIOK1 SGO1 ARID4A MSL3

6.18e-06576479int:H2BC8
InteractionH3C3 interactions

RLF RRP15 PHF14 CHD1 RIOK1 SGO1 ARID4A AFF4

1.70e-05495478int:H3C3
InteractionDHX40 interactions

RLF ANKRD11 RRP15 CHD1 COIL DROSHA

2.35e-05249476int:DHX40
InteractionELF2 interactions

ASXL2 LHX4 COIL ARID4A BANP

3.08e-05156475int:ELF2
InteractionCSNK2A1 interactions

ANKRD11 AUTS2 RRP15 CLASP2 NKTR ASXL2 RIOK1 MAP3K13 BRF1 NFKBIB

5.74e-059564710int:CSNK2A1
InteractionNOTO interactions

ANKRD11 UBTFL1 BANP

6.18e-0533473int:NOTO
InteractionZNF330 interactions

RLF ANKRD11 PHF14 CHD1 RIOK1 COIL AFF4

7.26e-05446477int:ZNF330
InteractionZBTB2 interactions

PHF14 CHD1 NKTR LHX4 COIL SHTN1 PPP1R12A

7.68e-05450477int:ZBTB2
InteractionAPEX1 interactions

RLF ANKRD11 RRP15 FAM193A BRF1 COIL ARID4A DROSHA PPP1R12A AFF4 MSL3

1.27e-0412714711int:APEX1
InteractionPOLR1G interactions

ANKRD11 RRP15 PHF14 CHD1 COIL AFF4 NFKBIB

1.29e-04489477int:POLR1G
InteractionPAF1 interactions

CHD1 COIL SGO1 AFF4 MSL3

1.37e-04214475int:PAF1
InteractionPARP1 interactions

RLF OTUD4 RRP15 PHF14 CHD1 ASXL2 ULK1 BRF1 COIL AFF4 BANP

1.73e-0413164711int:PARP1
InteractionMLLT1 interactions

CHD1 COIL ARID4A AFF4

1.92e-04123474int:MLLT1
InteractionHDAC1 interactions

RLF GON4L PHF14 CHD1 RIOK1 COIL SHTN1 ARID4A KNL1 BANP

1.95e-0411084710int:HDAC1
GeneFamilyAnkyrin repeat domain containing

ANKRD11 ANKRD31 ANK1 ANK2 PPP1R12A NFKBIB

1.59e-06242286403
GeneFamilyLIM class homeoboxes

LHX4 LMX1A

1.51e-0412282522
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CSRNP2 PPP1R12A KNL1

2.69e-03181283694
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

MYT1L AKAP6 AUTS2 OTUD4 PDE4D NRXN3 BRF1 ANK1 ANK2 SHTN1 ARID4A

2.46e-0611064611M39071
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS

AUTS2 CLASP2 PDE4D ANK2 SHTN1

4.04e-06136465MM407
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

ANKRD11 GON4L PHF14 MAP3K13 PDE4D ANK1 ARID4A

7.69e-06417467M39224
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

MYT1L CLASP2 PDE4D NRXN3 ANK1 ANK2 SHTN1

6.62e-05584467M39068
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000

OTUD4 CHD1 CLASP2 ASXL2 PPP1R12A KNL1

3.70e-06203446gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

AKAP6 RLF OTUD4 PHOX2A CLASP2 ASXL2 NRXN3 ANK2 SHTN1 PPP1R12A

5.14e-068184410DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

OTUD4 CHD1 PHOX2A CLASP2 ASXL2 NRXN3 FAM193A ANK2 SHTN1 PPP1R12A

5.14e-068184410gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000

FNIP2 AUTS2 CLASP2 ASXL2 ANK2

1.78e-05157445gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k3
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

FNIP2 ASXL2 RIOK1 CSRNP2 ARID4A PPP1R12A KNL1 BANP

1.80e-05564448Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

RLF OTUD4 CHD1 CLASP2 ASXL2 FAM193A

1.07e-04369446DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

GON4L PHF14 CHD1 NKTR FAM193A ARID4A AFF4 KNL1

2.70e-04831448Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A CLASP2 ANK2

1.65e-061894753f5522be3e24dcdb6272f18cee2f239dfdeff9ad
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A CLASP2 ANK2

1.87e-061944755bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A CLASP2 ANK2

2.02e-06197475fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

MYT1L PHF14 NRXN3 ANK2 SHTN1

2.07e-06198475de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A CLASP2 ANK2

2.12e-0619947547466253069d4b1b8f13ce3210f434e60753b38a
ToppCellNeuron|World / Primary Cells by Cluster

MYT1L AUTS2 ANK2 SHTN1 ARID4A

2.12e-061994751f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

MYT1L AUTS2 ANK2 SHTN1 ARID4A

2.12e-061994751973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

MYT1L AUTS2 ANK2 SHTN1 ARID4A

2.12e-06199475058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AUTS2 NRXN3 ANK2 ARID4A

2.18e-06200475979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

MYT1L MAP3K13 ULK1 NRXN3

1.33e-05137474b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L PHOX2A NRXN3 ANK1

3.16e-0517147499176a932569fa1c7e1c01009684f5a65244b96e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

3.78e-05179474b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A CLASP2 ANK2

3.95e-051814747f99002a6411117cc2361334c7c9228e20c574b4
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

4.03e-05182474be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLASP2 LHX4 DROSHA BANP

4.03e-051824744cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L NRXN3 ANK1 LMX1A

4.21e-051844747d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D NRXN3 ANK1 LMX1A

4.30e-05185474cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D NRXN3 ANK1 LMX1A

4.30e-0518547470de48988c1f8e0809afc8092b663aa439d8e528
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

4.30e-0518547494d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D NRXN3 ANK1 LMX1A

4.39e-05186474d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D NRXN3 ANK1 LMX1A

4.48e-051874747b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

4.58e-05188474bd091503f580dedab40e0996273101285d24b586
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RLF ANKRD11 CHD1 NKTR

4.58e-05188474ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

AUTS2 MAP3K13 PDE4D NRXN3

4.58e-05188474ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 CLASP2 PDE4D PPP1R12A

4.58e-0518847434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FNIP2 AKAP6 PDE4D ANK2

4.67e-051894740a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FNIP2 AKAP6 PDE4D ANK2

4.77e-0519047493c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A CLASP2 ANK2

4.87e-0519147473b15ffa60d592c43aaa575f1b1479d49a66dfe8
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A CLASP2 ANK2

4.97e-051924742f1c4ef693515ccc7231bd8c6641fad51d445d20
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

4.97e-05192474d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

4.97e-05192474307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

AUTS2 MAP3K13 PDE4D NRXN3

4.97e-0519247406013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CASC3 CLASP2 ASXL2 PDE4D

4.97e-05192474445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.07e-051934749661ea0ee7273928c7de2a9f49e853595fa77699
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.07e-05193474a189d46c39067b717509cd144e0225cc93d7731d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.07e-051934748851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKRD11 AUTS2 NKTR PDE4D

5.17e-051944746be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.27e-051954745a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.49e-05197474b9478212f14b7888e3abac02995177974ac3bd17
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.49e-051974745593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.49e-05197474a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.49e-05197474a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A CLASP2 ANK2

5.49e-05197474c220102fadbb7ba385a61704a144e0b814cb5c46
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.60e-0519847485881637641d8996be2edc65c4bceff0433135e7
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AUTS2 NRXN3 SHTN1

5.60e-05198474076c862f2a723f0361749377561cae902068b1a0
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_CHODL+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MYT1L AKAP6 PHOX2A ANK2

5.60e-05198474eb3c389e7452d74e5e15179503e480d6d11ca9ca
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.60e-05198474800ade4261695f2efd869d2b1243571de963c431
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A CLASP2 ANK2

5.60e-051984746483d412b6c0aab58b3348f99231caa5daf65025
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.60e-05198474dac7b68bb8f1c4d8aa7fdfada61f79956866e874
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.71e-05199474b4824d3683a4e3025b8e74a0f1755b331b2a0ba7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MYT1L ANK2 SHTN1 ARID4A

5.71e-051994745de2a32bc2e9c752eb19a013b1807949153728fc
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A ANK2

5.71e-05199474ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCelllymphoid-NK_cell-NK_cell|NK_cell / Lineage, cell class and subclass

ANKRD11 CHD1 PDE4D NFKBIB

5.71e-05199474945fbf5845403a8b22d04963f50ad69c414b6153
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-Neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AUTS2 CLASP2 SHTN1

5.82e-05200474b9538eb33ac86384e7e289a5a82fac4d56a7b9c2
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal-Neurons|GW09 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AUTS2 SHTN1 ARID4A

5.82e-05200474ddac952ad1d46021c2d17d816de9bc31730a0941
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AUTS2 ANK2 ARID4A

5.82e-0520047468c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ANKRD11 CHD1 PDE4D AFF4

5.82e-052004747dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD11 CHD1 NKTR AFF4

5.82e-0520047412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

MYT1L PHF14 ANK2 SHTN1

5.82e-052004746bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

MYT1L PHF14 ANK2 SHTN1

5.82e-05200474c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L NRXN3 SHTN1

2.25e-041124739c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FNIP2 ANKRD11 NKTR

3.89e-04135473b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNIP2 CASC3 NRXN3

5.09e-04148473ba277c898678dd36f8dc1d681301c71901b89055
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNIP2 CASC3 NRXN3

5.09e-04148473b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

AKAP6 PDE4D PPP1R12A

5.60e-04153473ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

ANKRD31 KNL1 MSL3

5.71e-0415447326bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK1 SHTN1 KNL1

5.93e-041564738349604bd801e20d33770f7d8243598c3756302b
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCLRE1A SGO1 KNL1

6.15e-04158473ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYT1L GON4L COIL

6.27e-04159473235ed12053b337aca5abc2ce8727332b4ae3f8ae
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

FNIP2 LHX4 SHTN1

6.50e-041614739fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASC3 CSRNP2 DROSHA

6.73e-04163473953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D ANK1 LMX1A

7.10e-04166473ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCLRE1A SGO1 KNL1

7.22e-04167473108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SGO1 SHTN1 KNL1

7.35e-041684734c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

LHX4 SGO1 KNL1

7.48e-04169473eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

FNIP2 AUTS2 MAP3K13

7.61e-04170473269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK1 SHTN1 KNL1

7.61e-041704739e94fa0d05abed3438b28296a293767096d517d6
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 SGO1 KNL1

7.74e-04171473ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCelldroplet-Spleen-SPLEEN|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 SGO1 KNL1

7.87e-04172473d32731a56e113ff0ef7167b23959d69baf2068f9
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 SGO1 KNL1

7.87e-0417247395219814e37259e34be053572cc95d4639360c27
ToppCelldroplet-Spleen-SPLEEN-30m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 SGO1 KNL1

7.87e-0417247302cc4a9fb7902c572cee37ba828749db4913ee87
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCLRE1A CSRNP2 KNL1

7.87e-0417247329c8510f26527d487d0fc3543102d067cdb281a6
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EAF2 SGO1 KNL1

8.00e-04173473b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L SHTN1

8.12e-0440472a55d9861170f41049748cd093d3d680855553d1d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal-Neurons|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L SHTN1

8.12e-04404727d7dc8dd5b095b7e3a83cbf840c4ee4f650bbc7c
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RIOK1 PDE4D SHTN1

8.13e-04174473feed99acd868db61f045e666dbfdcaed91ca1488
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L AKAP6 PHOX2A

8.13e-04174473271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 SGO1 KNL1

8.13e-0417447341eb0a214a8b4015a26311f77061c8147144f0e7
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EAF2 SGO1 KNL1

8.27e-041754739de288c338cee67be0e9b836c87799bbc1db1c38
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 SGO1 KNL1

8.27e-04175473d43ae33a6256606ce848247cad32d74f21b38988
ToppCellCaecum-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

AUTS2 SHTN1 MSL3

8.41e-0417647307cde50e1c18fcc2c5028efe1a087db4ef4d4783
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

FNIP2 MAP3K13 SHTN1

8.41e-04176473195393b38f1335f2cb96125616d75c164a6026c2
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A ANK2

8.41e-04176473bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYT1L SGO1 KNL1

8.41e-041764738385435074cc5235b7af7424974f609388fc2cff
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L PHOX2A ANK2

8.41e-041764733c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNIP2 SHTN1 KNL1

8.55e-0417747367cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCellIIH-CD8-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

ULK1 AFF4 MSL3

8.55e-04177473fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PHOX2A NRXN3 ANK2

8.69e-04178473d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_DZ|tumor_Lung / Location, Cell class and cell subclass

EAF2 SGO1 KNL1

8.69e-04178473c57f92e57548638f1627dc7d313137f406dbecff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FNIP2 AUTS2 PDE4D

8.69e-04178473f5ed4a6e3eb8056b1be1fb311021710c95bdf888
DiseaseIntellectual Disability

MYT1L AKAP6 GON4L BRF1 PPP1R12A MSL3

5.07e-05447446C3714756
Diseasealcohol consumption measurement

MYT1L AKAP6 ANKRD11 AUTS2 ASXL2 NRXN3 ARID4A LMX1A AFF4

7.54e-051242449EFO_0007878
Diseaseunderweight body mass index status

NRXN3 ANK2

7.77e-059442EFO_0005936
DiseaseFacies

AFF4 MSL3

9.71e-0510442C0282631
Diseasemortality

MYT1L AUTS2 PHF14 NRXN3

1.29e-04173444EFO_0004352
Diseasecognitive function measurement, self reported educational attainment

AKAP6 AUTS2 PDE4D FAM193A KNL1

1.81e-04355445EFO_0004784, EFO_0008354
DiseaseAutism Spectrum Disorders

MYT1L ANKRD11 NRXN3

2.81e-0485443C1510586
DiseaseNeurodevelopmental Disorders

MYT1L ANKRD11 ANK2

3.66e-0493443C1535926
Diseaseresponse to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema

PDE4D LMX1A

6.90e-0426442EFO_0005325, EFO_0005532, EFO_0010735
DiseaseBone Diseases, Developmental

ANK1 AFF4

7.45e-0427442C0005941
Diseaseinterleukin-8 measurement

MYT1L AUTS2

9.83e-0431442EFO_0004811
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

AKAP6 AUTS2 PHOX2A NRXN3 SHTN1 ARID4A

1.15e-03801446EFO_0003888, EFO_0007052, MONDO_0002491
Diseasegait measurement

AKAP6 AUTS2 NRXN3

1.46e-03150443EFO_0007680
Diseasetransient cerebral ischemia (biomarker_via_orthology)

PDE4D ANK1 ANK2

1.67e-03157443DOID:224 (biomarker_via_orthology)
Diseaseage at first sexual intercourse measurement

AKAP6 ERICH2 SHTN1 ARID4A

2.52e-03383444EFO_0009749
Diseasecoffee consumption measurement

FNIP2 AKAP6 AUTS2

2.54e-03182443EFO_0006781
Diseaseresponse to trauma exposure

MAP3K13 PDE4D

2.65e-0351442EFO_0008483
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 KNL1

3.52e-0359442EFO_0001663, MONDO_0005148

Protein segments in the cluster

PeptideGeneStartEntry
DGESGSEASDSVSSC

BANP

176

Q8N9N5
SKGESDEELSDESSD

ERICH2

136

A1L162
GKSDSCSSDSETEDA

ARID4A

691

P29374
FCSSESESESSESGE

ANKRD11

476

Q6UB99
DDEISSSDSADSCDS

CSRNP2

26

Q9H175
EDSSLECSKAEDSDA

ANK1

1581

P16157
GSDSESEEEREKSSC

CHD1

161

O14646
SEEEREKSSCDETES

CHD1

166

O14646
GDESADEDSCSEHSS

FAM193A

761

P78312
GESSSSKEDDTDEES

ASXL2

1171

Q76L83
LSSSEDSDGEQDCDK

AFF4

386

Q9UHB7
LTCDSSTSSSDDDEE

C18orf25

211

Q96B23
EDNSEISDSEDDSCK

OTUD4

196

Q01804
KQEESSSSSDPDADC

ANK2

2616

Q01484
DDDDDCSTSEKAITS

ANKRD31

901

Q8N7Z5
SCTGSDKGDESQDEE

MAGEB4

76

O15481
CKAEFEDSDTETSSS

GPBP1L1

451

Q9HC44
CSSSSDSDSGDEGDE

NFKBIB

311

Q15653
AASDSGKSDDEESLC

LMX1A

161

Q8TE12
DSGSQVEEDTSCSDS

PDE4D

751

Q08499
SSSDCSENKDEEISE

MSL3

131

Q8N5Y2
SDDLVSSAECSSDDE

NRXN3

1311

Q9Y4C0
SCRDSDSESASGESK

AUTS2

181

Q8WXX7
CDSDSDQEEKASDAS

AUTS2

221

Q8WXX7
KESPSSSSESESCDE

COIL

241

P38432
SSSESESCDESISDG

COIL

246

P38432
ESHSQSKSSSDECEE

KNL1

626

Q8NG31
EKESSAEDCGVSDSE

LHX4

241

Q969G2
SEDASKDSGEGSCSD

PHF14

46

O94880
SDCDSSDGECSDATV

MAP3K13

941

O43283
SGGAKSAEESECESE

CASC3

66

O15234
EDSSSDSEDEDCKSS

EAF2

191

Q96CJ1
DSEDEDCKSSTSDTG

EAF2

196

Q96CJ1
ESSDSALGDSDDEAC

FNIP2

891

Q9P278
TACEASSEDEDDATS

GON4L

2206

Q3T8J9
TESSKDGSLEEDDDS

DCLRE1A

326

Q6PJP8
SDSEDIGSSECSDTD

RIOK1

496

Q9BRS2
SESECESDEDSTCSS

DROSHA

481

Q9NRR4
SSDKEEGEATSDSES

NKTR

906

P30414
SDDLVSSAECSSDDE

NRXN3

306

Q9HDB5
VSLCESSGSGDDSDD

SGO1

366

Q5FBB7
DEDSTTDTDGAAETC

SHTN1

121

A0MZ66
CTDDEDDSDLLSSST

AKAP6

1746

Q13023
SDDDANSDASSACSE

CLASP2

621

O75122
EEESSNSLDCSSGED

UBTFL6

381

P0CB48
DREKEESSNSSDCSS

UBTFL1

371

P0CB47
ESSNSSDCSSGEEIE

UBTFL1

376

P0CB47
DLESSCEETESKTSD

RLF

1256

Q13129
GEARCSSEDDDSKES

PHOX2A

166

O14813
SSEDDDSKESTCSPT

PHOX2A

171

O14813
DTSDSEGSCGSEKDH

RRP15

41

Q9Y3B9
STEDTASSLCGEEDT

BRF1

351

Q92994
SRDSGGSKDSSCDTD

ULK1

341

O75385
EEGKKDESSCSSEED

PPP1R12A

346

O14974
KADSSSVDECDDSDG

MYT1L

81

Q9UL68