Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	5.45e-12	431	115	19	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 PPARG OR51L1 CELSR1 OR5AC2 OR4A5 OR1A1 ADGRD1 GPR148 OR2AG1	1.03e-09	884	115	23	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 ACVR1 PPARG IFNAR2 SORT1 OR51L1 CELSR1 OR5AC2 OR4A5 PKD1 OR1A1 ADGRD1 GPR148 OR2AG1	9.21e-09	1353	115	27	GO:0004888
GeneOntologyMolecularFunction	gap junction channel activity involved in cell communication by electrical coupling	GJC2 GJA1 GJC3	1.52e-05	9	115	3	GO:1903763
GeneOntologyMolecularFunction	RNA transmembrane transporter activity	SIDT1 SIDT2	9.83e-05	3	115	2	GO:0051033
GeneOntologyMolecularFunction	nucleic acid transmembrane transporter activity	SIDT1 SIDT2	9.83e-05	3	115	2	GO:0051032
GeneOntologyMolecularFunction	gap junction channel activity involved in cardiac conduction electrical coupling	GJA1 GJC3	3.25e-04	5	115	2	GO:0086075
GeneOntologyMolecularFunction	gap junction channel activity	GJC2 GJA1 GJC3	3.90e-04	25	115	3	GO:0005243
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	2.77e-12	432	114	19	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	9.98e-12	465	114	19	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	2.06e-11	485	114	19	GO:0050907
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 PPARG ADCYAP1 SORT1 GPR180 OR51L1 CELSR1 OR5AC2 OR4A5 TMEM145 OR1A1 TENM1 CALY ADGRD1 GPR148 RAPGEFL1 OR2AG1	6.67e-11	1395	114	30	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	7.74e-11	524	114	19	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	1.60e-10	547	114	19	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	4.54e-10	582	114	19	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 PKD1 OR1A1 GPR148 OR2AG1	2.57e-09	722	114	20	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GJC3 GPR148 OR2AG1	1.58e-06	1072	114	20	GO:0007600
GeneOntologyBiologicalProcess	regulation of oligodendrocyte progenitor proliferation	GJC2 ADCYAP1 AFDN	3.49e-05	12	114	3	GO:0070445
GeneOntologyBiologicalProcess	oligodendrocyte progenitor proliferation	GJC2 ADCYAP1 AFDN	4.52e-05	13	114	3	GO:0070444
GeneOntologyBiologicalProcess	positive regulation of mitochondrial ATP synthesis coupled electron transport	CCNB1 GHITM	1.80e-04	4	114	2	GO:1905448
GeneOntologyCellularComponent	endoplasmic reticulum membrane	OR5T3 OR2M7 AGPAT5 OR2M2 SEC24A UBXN8 ALG11 SLC28A3 OR2M5 OR2M3 SORT1 GJA1 SGMS1 ERAP2 GUCY2C FDFT1 TMEM106C HHAT LRBA SLC27A3	2.10e-05	1293	114	20	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	OR5T3 OR2M7 AGPAT5 OR2M2 SEC24A UBXN8 ALG11 SLC28A3 OR2M5 OR2M3 SORT1 GJA1 SGMS1 ERAP2 GUCY2C FDFT1 TMEM106C HHAT LRBA SLC27A3	2.25e-05	1299	114	20	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	OR5T3 OR2M7 AGPAT5 OR2M2 SEC24A UBXN8 ALG11 SLC28A3 OR2M5 OR2M3 SORT1 GJA1 SGMS1 ERAP2 GUCY2C FDFT1 TMEM106C HHAT LRBA SLC27A3	3.05e-05	1327	114	20	GO:0042175
GeneOntologyCellularComponent	connexin complex	GJC2 GJA1 GJC3	2.26e-04	22	114	3	GO:0005922
HumanPheno	Lymphedema	RAF1 GJC2 TSC2 ACVR1 CELSR1 GUSB	1.23e-05	76	36	6	HP:0001004
MousePheno	small lung	RAF1 ZNF521 THOC2 GREB1L CELSR1 PKD1 MAPK6 CPLANE1	2.38e-07	115	78	8	MP:0003641
MousePheno	abnormal lung size	RAF1 ZNF521 NR3C1 THOC2 GREB1L CELSR1 PKD1 MAPK6 CPLANE1	5.09e-07	174	78	9	MP:0004881
MousePheno	abnormal respiratory system morphology	RAF1 DYNC2H1 POLE ZNF521 LAMA3 MCM4 TSC2 NR3C1 THOC2 GREB1L GJA1 CELSR1 MAN1A2 GUSB HHAT PKD1 MAPK6 CPLANE1	1.04e-05	1027	78	18	MP:0002132
MousePheno	pulmonary hypoplasia	GREB1L CELSR1 PKD1 MAPK6 CPLANE1	1.21e-05	54	78	5	MP:0001178
MousePheno	abnormal lung morphology	RAF1 DYNC2H1 POLE ZNF521 LAMA3 MCM4 TSC2 NR3C1 THOC2 GREB1L CELSR1 MAN1A2 PKD1 MAPK6 CPLANE1	1.84e-05	767	78	15	MP:0001175
Domain	Olfact_rcpt	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 OR2AG1	2.81e-11	393	114	18	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	3.83e-09	670	114	20	IPR017452
Domain	7tm_1	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	4.57e-09	677	114	20	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	5.57e-09	685	114	20	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	6.46e-09	691	114	20	PS50262
Domain	GPCR_Rhodpsn	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 GALR3 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 GPR148 OR2AG1	6.62e-09	692	114	20	IPR000276
Domain	SID1_TM_fam	SIDT1 SIDT2	3.69e-05	2	114	2	IPR025958
Domain	Intimal_thickness-rel_rcpt	GPR180 TMEM145	3.69e-05	2	114	2	IPR019336
Domain	SID-1_RNA_chan	SIDT1 SIDT2	3.69e-05	2	114	2	PF13965
Domain	TTC39A/B	TTC39B TTC39A	3.69e-05	2	114	2	IPR030416
Domain	GpcrRhopsn4	GPR180 TMEM145	3.69e-05	2	114	2	PF10192
Domain	DUF3808	TTC39B TTC39A	1.10e-04	3	114	2	PF10300
Domain	OMP_Iml2/TPR_39	TTC39B TTC39A	1.10e-04	3	114	2	IPR019412
Domain	CONNEXINS_1	GJC2 GJA1 GJC3	2.00e-04	19	114	3	PS00407
Domain	Tox-GHH_dom	TENM3 TENM1	2.20e-04	4	114	2	IPR028916
Domain	Ten_N	TENM3 TENM1	2.20e-04	4	114	2	IPR009471
Domain	Ten_N	TENM3 TENM1	2.20e-04	4	114	2	PF06484
Domain	TENEURIN_N	TENM3 TENM1	2.20e-04	4	114	2	PS51361
Domain	Tox-GHH	TENM3 TENM1	2.20e-04	4	114	2	PF15636
Domain	CONNEXINS_2	GJC2 GJA1 GJC3	2.34e-04	20	114	3	PS00408
Domain	Connexin	GJC2 GJA1 GJC3	2.34e-04	20	114	3	IPR000500
Domain	Connexin_CCC	GJC2 GJA1 GJC3	2.34e-04	20	114	3	IPR019570
Domain	Connexin_N	GJC2 GJA1 GJC3	2.34e-04	20	114	3	IPR013092
Domain	Connexin	GJC2 GJA1 GJC3	2.34e-04	20	114	3	PF00029
Domain	Connexin_CCC	GJC2 GJA1 GJC3	2.34e-04	20	114	3	SM01089
Domain	Connexin_CS	GJC2 GJA1 GJC3	2.34e-04	20	114	3	IPR017990
Domain	CNX	GJC2 GJA1 GJC3	2.34e-04	20	114	3	SM00037
Domain	YD	TENM3 TENM1	3.65e-04	5	114	2	IPR006530
Domain	GPS	CELSR1 PKD1 ADGRD1	1.15e-03	34	114	3	SM00303
Domain	GPS	CELSR1 PKD1 ADGRD1	1.26e-03	35	114	3	PF01825
Domain	GPS	CELSR1 PKD1 ADGRD1	1.37e-03	36	114	3	PS50221
Domain	GPS	CELSR1 PKD1 ADGRD1	1.48e-03	37	114	3	IPR000203
Domain	Rap_GAP	SIPA1L3 TSC2	1.61e-03	10	114	2	PF02145
Domain	Rap_GAP_dom	SIPA1L3 TSC2	1.96e-03	11	114	2	IPR000331
Domain	RAPGAP	SIPA1L3 TSC2	1.96e-03	11	114	2	PS50085
Domain	-	LAMA3 CELSR1 LRBA ADGRD1	2.74e-03	95	114	4	2.60.120.200
Domain	NHL	TENM3 TENM1	2.76e-03	13	114	2	PS51125
Domain	Pept_M10A_Zn_BS	MMP1 MMP3	3.68e-03	15	114	2	IPR021158
Domain	Hemopexin_CS	MMP1 MMP3	4.73e-03	17	114	2	IPR018486
Domain	Pept_M10A_stromelysin-type	MMP1 MMP3	5.30e-03	18	114	2	IPR016293
Domain	Ubiquitin-rel_dom	RAF1 UBXN8 UBLCP1 AFDN RAPGEFL1	5.43e-03	184	114	5	IPR029071
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 OR2AG1	9.21e-11	417	89	18	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 OR2AG1	2.72e-10	389	89	17	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR51L1 OR5AC2 OR4A5 OR1A1 OR2AG1	7.12e-08	636	89	18	M41834
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR4A5 OR1A1 OR2AG1	3.51e-14	340	116	16	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR4A5 OR1A1 OR2AG1	3.51e-14	340	116	16	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR4A5 OR1A1 OR2AG1	4.02e-14	343	116	16	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5T1 OR5T3 OR2M7 OR2L3 OR2M2 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR6C65 OR2M3 OR4A5 OR1A1 OR2AG1	4.60e-14	346	116	16	14611657
Pubmed	High-throughput microarray detection of olfactory receptor gene expression in the mouse.	OR2M7 OR2M2 OR2M5 OR2M3	1.17e-10	4	116	4	15377787
Pubmed	The human olfactory receptor gene family.	OR5T1 OR5T3 OR2M7 OR2AP1 OR1S1 OR1S2 OR6C74 OR10H4 OR2M5 OR2M3 OR51L1 OR4A5 OR1A1 OR2AG1	3.90e-09	541	116	14	14983052
Pubmed	The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development.	GJC2 CCNB1 GJA1 GJC3	5.70e-08	12	116	4	11501764
Pubmed	Oleic acid activates MMPs up-regulation through SIRT1/PPAR-γ inhibition: a probable linkage between obesity and coronary arterial disease.	PPARG MMP1 MMP3	1.44e-07	4	116	3	27072559
Pubmed	Location of the 9257 and ataxia mutations on mouse chromosome 18.	ZNF521 LAMA3 NR3C1	2.99e-06	9	116	3	8662222
Pubmed	No association between matrix metalloproteinase-1 or matrix metalloproteinase-3 polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer Study.	MMP1 MMP3	1.10e-05	2	116	2	19318431
Pubmed	Overexpression of matrix metalloproteinase-1 (MMP-1) and MMP-3 in superior limbic keratoconjunctivitis.	MMP1 MMP3	1.10e-05	2	116	2	21357403
Pubmed	Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with carotid artery stenosis.	MMP1 MMP3	1.10e-05	2	116	2	12364729
Pubmed	[Single nucleotide polymorphism in the matrix metalloproteinases promoter is associated with susceptibility to endometriosis and adenomyosis].	MMP1 MMP3	1.10e-05	2	116	2	16202315
Pubmed	Effects of melittin on the production of matrix metalloproteinase-1 and -3 in rheumatoid arthritic fibroblast-like synoviocytes.	MMP1 MMP3	1.10e-05	2	116	2	18212480
Pubmed	No association between the polymorphisms in matrix metalloproteinase-1 and matrix metalloproteinase-3 promoter regions and colorectal cancer in Chinese.	MMP1 MMP3	1.10e-05	2	116	2	16937230
Pubmed	[MMP-1 and MMP-3 gene encoding polymorphism and the risk of the development of pelvic organ prolapse and stress urinary incontinence].	MMP1 MMP3	1.10e-05	2	116	2	20873121
Pubmed	The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1.	TSC2 CCNB1	1.10e-05	2	116	2	21900748
Pubmed	An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development.	CCNB1 PKD1	1.10e-05	2	116	2	34858418
Pubmed	Human cytomegalovirus induces MMP-1 and MMP-3 expression in aortic smooth muscle cells.	MMP1 MMP3	1.10e-05	2	116	2	22207289
Pubmed	Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients.	MMP1 MMP3	1.10e-05	2	116	2	21345293
Pubmed	MMP-1 and -3 haplotype is associated with congenital anomalies of the kidney and urinary tract.	MMP1 MMP3	1.10e-05	2	116	2	24414606
Pubmed	Pro-inflammatory IL-1beta and/or TNF-alpha up-regulate matrix metalloproteases-1 and -3 mRNA in chondrocyte subpopulations potentially pathogenic in osteoarthritis: in situ hybridization studies on a single cell level.	MMP1 MMP3	1.10e-05	2	116	2	25291965
Pubmed	Association of matrix metalloproteinase-1 and -3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients.	MMP1 MMP3	1.10e-05	2	116	2	15288468
Pubmed	A single nucleotide polymorphism in the matrix metalloproteinase-3 promoter enhances breast cancer susceptibility.	MMP1 MMP3	1.10e-05	2	116	2	12473595
Pubmed	MMP1 and MMP3 gene polymorphisms in patients with acute coronary syndromes.	MMP1 MMP3	1.10e-05	2	116	2	29044936
Pubmed	MMP gene polymorphisms as contributors for cleft lip/palate: association with MMP3 but not MMP1.	MMP1 MMP3	1.10e-05	2	116	2	17537400
Pubmed	Polymorphism of MMP1 and MMP3 promoter regions and HR-HPV infection in women from Burkina Faso and Côte d'Ivoire.	MMP1 MMP3	1.10e-05	2	116	2	32417757
Pubmed	MMP-1 and MMP-3 polymorphism and arrhythmia recurrence after electrical cardioversion in patients with persistent atrial fibrillation.	MMP1 MMP3	1.10e-05	2	116	2	20935575
Pubmed	Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation.	MMP1 MMP3	1.10e-05	2	116	2	19906289
Pubmed	Connexin 43/47 channels are important for astrocyte/ oligodendrocyte cross-talk in myelination and demyelination.	GJC2 GJA1	1.10e-05	2	116	2	30541963
Pubmed	Acrofacial dysostosis in a patient with the TSC2-PKD1 contiguous gene syndrome.	TSC2 PKD1	1.10e-05	2	116	2	11836366
Pubmed	In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protein kinase-dependent pathway.	MMP1 MMP3	1.10e-05	2	116	2	23978194
Pubmed	Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.	MMP1 MMP3	1.10e-05	2	116	2	16899023
Pubmed	Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China.	MMP1 MMP3	1.10e-05	2	116	2	15528217
Pubmed	Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with mortality in haemodialysis patients.	MMP1 MMP3	1.10e-05	2	116	2	19221176
Pubmed	Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways.	RAF1 NR3C1	1.10e-05	2	116	2	11005817
Pubmed	Investigation of the relationship between MMP-1 (- 1607 1G/2G), MMP-3 (- 1171 5A/6A) gene variations and development of bladder cancer.	MMP1 MMP3	1.10e-05	2	116	2	34693500
Pubmed	Prostaglandin-J(2) upregulates expression of matrix metalloproteinase-1 independently of activation of peroxisome proliferator-activated receptor-gamma.	PPARG MMP1	1.10e-05	2	116	2	14515149
Pubmed	Single nucleotide polymorphisms in MMP1 and MMP3 gene promoters as risk factor in head and neck squamous cell carcinoma.	MMP1 MMP3	1.10e-05	2	116	2	15274394
Pubmed	Analysis of PKD1 for genomic deletion by multiplex ligation-dependent probe assay: absence of hot spots.	TSC2 PKD1	1.10e-05	2	116	2	18060739
Pubmed	TSC2/PKD1 contiguous gene syndrome, with emphasis on a case with an atypical mild polycystic kidney phenotype and a novel genetic variant.	TSC2 PKD1	1.10e-05	2	116	2	31176519
Pubmed	Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.	MMP1 MMP3	1.10e-05	2	116	2	31356534
Pubmed	Matrix Metalloproteases 1 and 3 Promoter Gene Polymorphism Is Associated With Rotator Cuff Tear.	MMP1 MMP3	1.10e-05	2	116	2	28160256
Pubmed	Polymorphisms of MMP-1 and MMP-3 and susceptibility to rheumatoid arthritis. A meta-analysis.	MMP1 MMP3	1.10e-05	2	116	2	25854159
Pubmed	Hyaluronate inhibits the interleukin-1beta-induced expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human synovial cells.	MMP1 MMP3	1.10e-05	2	116	2	15383690
Pubmed	Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts.	PKD1 MMP3	1.10e-05	2	116	2	21867693
Pubmed	A novel family of mammalian transmembrane proteins involved in cholesterol transport.	SIDT1 SIDT2	1.10e-05	2	116	2	28785058
Pubmed	Genetic Dimension of Intervertebral Disc Degeneration: Polymorphism of Matrix Metalloproteinase 1 and 3 in the North Iranian Population.	MMP1 MMP3	1.10e-05	2	116	2	28497435
Pubmed	Connexin43 and connexin47 alterations after neural precursor cells transplantation in experimental autoimmune encephalomyelitis.	GJC2 GJA1	1.10e-05	2	116	2	25914045
Pubmed	Association of a haplotype of matrix metalloproteinase (MMP)-1 and MMP-3 polymorphisms with renal cell carcinoma.	MMP1 MMP3	1.10e-05	2	116	2	15319295
Pubmed	Activation of human interstitial procollagenase through direct cleavage of the Leu83-Thr84 bond by mast cell chymase.	CMA1 MMP1	1.10e-05	2	116	2	8027075
Pubmed	Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo.	MMP1 MMP3	1.10e-05	2	116	2	12054564
Pubmed	Genetics of heart rate in heart failure patients (GenHRate).	GJA1 CELSR1	1.10e-05	2	116	2	31113495
Pubmed	The distribution and functional properties of Pelizaeus-Merzbacher-like disease-linked Cx47 mutations on Cx47/Cx47 homotypic and Cx47/Cx43 heterotypic gap junctions.	GJC2 GJA1	1.10e-05	2	116	2	23544880
Pubmed	The 2G allele of promoter region of matrix metalloproteinase-1 as an essential pre-condition for the early onset of oral squamous cell carcinoma.	MMP1 MMP3	1.10e-05	2	116	2	17919326
Pubmed	Promoter polymorphism of the matrix metalloproteinase 3 gene is associated with regurgitation and left ventricular remodelling in mitral valve prolapse patients.	MMP1 MMP3	1.10e-05	2	116	2	17765638
Pubmed	Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation.	MMP1 MMP3	1.10e-05	2	116	2	16972994
Pubmed	Diagnosis and genotype-phenotype correlation in patients with PKD1/TSC2 contiguous gene deletion syndrome.	TSC2 PKD1	1.10e-05	2	116	2	35142283
Pubmed	Polycystin 1 is required for the structural integrity of blood vessels.	TSC2 PKD1	1.10e-05	2	116	2	10677526
Pubmed	Variation of matrix metalloproteinase 1 and 3 haplotypes and their serum levels in patients with rheumatoid arthritis and osteoarthritis.	MMP1 MMP3	1.10e-05	2	116	2	21770773
Pubmed	The polymorphisms of the MMP-1 and the MMP-3 genes and the risk of pelvic organ prolapse.	MMP1 MMP3	1.10e-05	2	116	2	23108733
Pubmed	Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae.	MMP1 MMP3	1.10e-05	2	116	2	13129650
Pubmed	The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.	TSC2 PKD1	1.10e-05	2	116	2	8661056
Pubmed	The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling.	TSC2 CCNB1	1.10e-05	2	116	2	30629673
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	1.10e-05	2	116	2	37668106
Pubmed	Role of matrix metalloproteases 1/3 gene polymorphisms in patients with rotator cuff tear.	MMP1 MMP3	1.10e-05	2	116	2	31652448
Pubmed	Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression.	MMP1 MMP3	1.10e-05	2	116	2	17145822
Pubmed	Renal Neoplasia in Polycystic Kidney Disease: An Assessment of Tuberous Sclerosis Complex-associated Renal Neoplasia and PKD1/TSC2 Contiguous Gene Deletion Syndrome.	TSC2 PKD1	1.10e-05	2	116	2	34876325
Pubmed	PPARγ activation mitigates glucocorticoid receptor-induced excessive lipolysis in adipocytes via homeostatic crosstalk.	NR3C1 PPARG	1.10e-05	2	116	2	29266408
Pubmed	Influence of Matrix metalloproteinase 1 and 3 genetic variations on susceptibility and severity of juvenile idiopathic arthritis.	MMP1 MMP3	1.10e-05	2	116	2	26510114
Pubmed	Polymorphisms in the promoter regions of matrix metalloproteinases 1 and 3 and cancer risk: a meta-analysis of 50 case-control studies.	MMP1 MMP3	1.10e-05	2	116	2	19843588
Pubmed	Kaempferol inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of COX-2, PGE2 and MMPs.	MMP1 MMP3	1.10e-05	2	116	2	23934131
Pubmed	Metalloproteinases 1 and 3 as Potential Biomarkers in Breast Cancer Development.	MMP1 MMP3	1.10e-05	2	116	2	34445715
Pubmed	Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts.	MMP1 MMP3	1.10e-05	2	116	2	12071839
Pubmed	Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis.	MMP1 MMP3	1.10e-05	2	116	2	28002595
Pubmed	Two novel gross deletions of TSC2 in Malaysian patients with tuberous sclerosis complex and TSC2/PKD1 contiguous deletion syndrome.	TSC2 PKD1	1.10e-05	2	116	2	24683199
Pubmed	Imaging features of tuberous sclerosis complex with autosomal-dominant polycystic kidney disease: a contiguous gene syndrome.	TSC2 PKD1	1.10e-05	2	116	2	25355409
Pubmed	Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle.	MMP1 MMP3	1.10e-05	2	116	2	35912721
Pubmed	Epigallocatechin-3-gallate suppresses TNF-alpha -induced production of MMP-1 and -3 in rheumatoid arthritis synovial fibroblasts.	MMP1 MMP3	1.10e-05	2	116	2	18496696
Pubmed	[Clinical significance of functional variants of matrix metalloproteinase genes in thyroid cancer].	MMP1 MMP3	1.10e-05	2	116	2	19432148
Pubmed	Evaluation of MMP1 and MMP3 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.	MMP1 MMP3	1.10e-05	2	116	2	20038976
Pubmed	Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer.	MMP1 MMP3	1.10e-05	2	116	2	12432557
Pubmed	Comparison of human stromelysin and collagenase by cloning and sequence analysis.	MMP1 MMP3	1.10e-05	2	116	2	3030290
Pubmed	Polymorphism of matrix metalloproteinase genes (MMP1 and MMP3) in patients with varicose veins.	MMP1 MMP3	1.10e-05	2	116	2	19508478
Pubmed	Matrix metalloproteinase (MMP)-1 and MMP-3 gene variations affect MMP-1 and -3 serum concentration and associates with breast cancer.	MMP1 MMP3	1.10e-05	2	116	2	33170424
Pubmed	Enhanced cell cycle entry and mitogen-activated protein kinase-signaling and downregulation of matrix metalloproteinase-1 and -3 in human diabetic arterial vasculature.	MMP1 MMP3	1.10e-05	2	116	2	17316652
Pubmed	Influence of variations across the MMP-1 and -3 genes on the serum levels of MMP-1 and -3 and disease activity in rheumatoid arthritis.	MMP1 MMP3	1.10e-05	2	116	2	21753786
Pubmed	Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.	NR3C1 PPARG	1.10e-05	2	116	2	15531761
Pubmed	Intercellular calcium signaling between astrocytes and oligodendrocytes via gap junctions in culture.	GJC2 GJA1	1.10e-05	2	116	2	20211698
Pubmed	Association of Matrix Metalloproteinase-1 and Matrix Metalloproteinase-3 Gene Variants with Ischemic Stroke and Its Subtype.	MMP1 MMP3	1.10e-05	2	116	2	27793533
Pubmed	The function of the SNP in the MMP1 and MMP3 promoter in susceptibility to endometriosis in China.	MMP1 MMP3	1.10e-05	2	116	2	15879464
Pubmed	Association of matrix metalloproteinase (MMP)-1 promoter polymorphism with head and neck squamous cell carcinoma.	MMP1 MMP3	1.10e-05	2	116	2	15194213
Pubmed	Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.	SIDT1 SIDT2	1.10e-05	2	116	2	26067272
Pubmed	[Association of single nucleotide polymorphism in matrix metalloproteinases promoter with susceptibility to ovarian cancer].	MMP1 MMP3	1.10e-05	2	116	2	16080875
Pubmed	Analysis of two polymorphisms in the promoter region of matrix metalloproteinase 1 and 3 genes in women with endometriosis.	MMP1 MMP3	1.10e-05	2	116	2	16532917
Pubmed	Coeliac disease candidate genes: no association with functional polymorphisms in matrix metalloproteinase 1 and 3 gene promoters.	MMP1 MMP3	1.10e-05	2	116	2	12229968
Pubmed	Prognostic significance of MMP-1 and MMP-3 functional promoter polymorphisms in colorectal cancer.	MMP1 MMP3	1.10e-05	2	116	2	15701845
Pubmed	Digenic inheritance of severe insulin resistance in a human pedigree.	PPARG PPP1R3A	1.10e-05	2	116	2	12118251
Pubmed	Effects of MMP-1 and MMP-3 gene polymorphisms on gene expression and protein level in lumbar disc herniation.	MMP1 MMP3	1.10e-05	2	116	2	27706715
Pubmed	Identification of self-epitopes recognized by T cells in rheumatoid arthritis demonstrates matrix metalloproteinases as a novel T cell target.	MMP1 MMP3	1.10e-05	2	116	2	12784383
Cytoband	1q44	OR2M7 OR2L3 OR2M2 OR2M5 OR2M3	9.35e-06	110	116	5	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2M7 OR2L3 OR2M2 OR2M5 OR2M3	1.95e-05	128	116	5	chr1q44
Cytoband	18q11.2	ZNF521 LAMA3 GREB1L	2.35e-04	47	116	3	18q11.2
Cytoband	12q13.2	OR2AP1 OR6C74 OR6C65	3.75e-04	55	116	3	12q13.2
Cytoband	11q12.1	OR5T1 OR5T3 OR1S1 OR1S2	7.69e-04	161	116	4	11q12.1
Cytoband	3p25	RAF1 PPARG	8.40e-04	17	116	2	3p25
Cytoband	Ensembl 112 genes in cytogenetic band chr18q11	ZNF521 LAMA3 GREB1L	1.34e-03	85	116	3	chr18q11
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	DYNC2H1 MMP1 MMP3	2.58e-03	107	116	3	chr11q22
GeneFamily	Olfactory receptors, family 2	OR2M7 OR2L3 OR2M2 OR2AP1 OR2M5 OR2M3 OR2AG1	7.98e-07	113	82	7	149
GeneFamily	Gap junction proteins	GJC2 GJA1 GJC3	1.30e-04	22	82	3	314
GeneFamily	Olfactory receptors, family 1	OR1S1 OR1S2 OR1A1	7.87e-04	40	82	3	147
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	AGPAT5 MCM4 HEATR1 PPAT CCNB1 TYMS MAN1A2 TMEM106C MAPK6	1.05e-06	250	109	9	M11318
Coexpression	LINDGREN_BLADDER_CANCER_CLUSTER_3_UP	RAF1 REXO5 MCM4 PPAT CCNB1 TYMS TMEM106C AFDN TTC39A	9.60e-06	328	109	9	M854
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD GJA1 FRY BMX SGMS1 MALL AFDN	7.80e-07	194	116	7	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	Biopsy_IPF-Mesenchymal-Mesothelial_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	CPA1 SLC28A3 ADCYAP1 GJA1 TENM3 CDH6 STEAP1	9.56e-07	200	116	7	553386523fd8f8f36617a0d81032224b7ddce442
ToppCell	3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	MCM4 CCNB1 TYMS AFDN CDH6 STEAP1	9.96e-06	188	116	6	0e8ac42c439f30a05e015210e1d5c2dcb9d9d471
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF521 GJC2 GJA1 CELSR1 TENM3 MALL	1.06e-05	190	116	6	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF521 GJC2 GJA1 CELSR1 TENM3 MALL	1.06e-05	190	116	6	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF521 GJC2 GJA1 CELSR1 TENM3 MALL	1.06e-05	190	116	6	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SIPA1L3 SORT1 GREB1L TENM3 AFDN LRBA	1.09e-05	191	116	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PPARG GJA1 FRY MALL AFDN	1.09e-05	191	116	6	a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCell	facs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PPARG GJA1 FRY MALL AFDN	1.09e-05	191	116	6	827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPARG SORT1 GREB1L TENM3 AFDN LRBA	1.19e-05	194	116	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZNF717 LAMA3 PPARG CELSR1 UTP25 CFAP221	1.19e-05	194	116	6	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZNF717 LAMA3 PPARG CELSR1 UTP25 CFAP221	1.19e-05	194	116	6	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	356C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 GALR3 PPARG KMO BMX	6.05e-05	159	116	5	299e2162a82e31196d7f3a110c2db622349edfff
ToppCell	356C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 GALR3 PPARG KMO BMX	6.05e-05	159	116	5	0a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	GALR3 CPA1 GJC2 BMX TENM3	7.42e-05	166	116	5	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GALR3 CPA1 GJC2 BMX TENM3	7.42e-05	166	116	5	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	(3)_MNP-(3)_DC_plasmacytoid\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	AGPAT5 SIDT1 NR3C1 HHAT TTC39A	7.85e-05	168	116	5	13c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF717 LAMA3 PPARG CELSR1 UTP25	8.07e-05	169	116	5	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF717 LAMA3 PPARG CELSR1 UTP25	8.07e-05	169	116	5	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TYMS CELSR1 GUCY2C TTC39A SLC27A3	8.53e-05	171	116	5	1efce222989460bb59bd9fa955e7d9a60c73994c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REXO5 POLE MCM4 TYMS CMA1	8.53e-05	171	116	5	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	3'_v3-blood-Mast\|blood / Manually curated celltypes from each tissue	REXO5 ACO1 ZNF521 ADCYAP1 KMO	8.77e-05	172	116	5	e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DYNC2H1 POLE CCNB1 TYMS FDFT1	8.77e-05	172	116	5	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR3 SLC7A14 ADCYAP1 GREB1L CALY	9.26e-05	174	116	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK2 PPARG SORT1 SIDT2 SLC27A3	1.03e-04	178	116	5	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	MCM4 PPARG CCNB1 TYMS TMEM106C	1.14e-04	182	116	5	84018a84e1aa52fa52ccfc26db9cd1fb6d535b31
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZNF521 DCT GJA1 MMP1 MMP3	1.14e-04	182	116	5	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMA3 SLC28A3 CELSR1 MALL TTC39A	1.20e-04	184	116	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCM4 CCNB1 SLC5A11 TYMS TMEM106C	1.27e-04	186	116	5	993c58ef4445bf81bbc9b489635883848b5b4c8e
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	ZNF521 GJC2 GJA1 BMX TENM3	1.30e-04	187	116	5	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD ACVR1 CELSR1 BMX MALL	1.30e-04	187	116	5	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD ACVR1 CELSR1 BMX MALL	1.30e-04	187	116	5	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF521 GJC2 GJA1 CELSR1 MALL	1.33e-04	188	116	5	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF521 GJC2 GJA1 BMX SLC27A3	1.33e-04	188	116	5	26915db8863f4115b46a81982e187322e21600fd
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF521 GJC2 GJA1 CELSR1 MALL	1.33e-04	188	116	5	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF521 GJC2 GJA1 BMX SLC27A3	1.33e-04	188	116	5	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF521 GJC2 GJA1 BMX SLC27A3	1.33e-04	188	116	5	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD GJA1 BMX MALL SLC27A3	1.36e-04	189	116	5	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF521 ACVR1 CELSR1 BMX MALL	1.36e-04	189	116	5	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD GJA1 BMX MALL SLC27A3	1.36e-04	189	116	5	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF521 ACVR1 CELSR1 BMX MALL	1.40e-04	190	116	5	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 BNIPL AFDN SLC27A3 RAPGEFL1	1.43e-04	191	116	5	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD FRY CELSR1 BMX MALL	1.47e-04	192	116	5	14a816ef116aa992f86edab411f043cf7d07fe04
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SORT1 GREB1L FRY TENM3 LRBA	1.47e-04	192	116	5	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	facs-Heart-LA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD FRY CELSR1 BMX MALL	1.47e-04	192	116	5	847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	JCAD ADCYAP1 FRY BMX GJC3	1.50e-04	193	116	5	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2H1 CDHR3 CELSR1 CFAP221 CPLANE1	1.50e-04	193	116	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GJC2 DCT HHAT STEAP1	1.52e-04	103	116	4	287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCell	COVID-19-Myeloid-TRAM2\|COVID-19 / Condition, Lineage and Cell class	ACO1 PPARG KMO SORT1 SIDT2	1.54e-04	194	116	5	c5bdf2b58c10dcb09797ddaf46b2e6c80d10399f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SORT1 GREB1L TENM3 AFDN LRBA	1.54e-04	194	116	5	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPA1 SLC28A3 GJA1 ADGRD1 STEAP1	1.54e-04	194	116	5	421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCell	(7)_Epithelial-J_(AT1-AT2_progenitors)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMA3 MCM4 TYMS MALL TMEM106C	1.58e-04	195	116	5	70e6b58c502a2abeb4e36bed179020c675468bd4
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TTC39B REXO5 ADCYAP1 FRY CMA1	1.58e-04	195	116	5	fbedb9978ded857fd35c2a8664f7579f42edaa36
ToppCell	control-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	POLE MCM4 SLC28A3 TYMS TMEM106C	1.58e-04	195	116	5	bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF521 ACVR1 GREB1L CELSR1 BMX	1.62e-04	196	116	5	e386526332138e636aef2542c11316347a45689c
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD ZNF521 GJA1 BMX AFDN	1.62e-04	196	116	5	629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAN2A2 GJC2 SLC7A14 SORT1 SLC5A11	1.66e-04	197	116	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TTC39B REXO5 ZNF521 ADCYAP1 CMA1	1.66e-04	197	116	5	61f909737c5f630beffdd326c6844215643dbdde
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACO1 PPARG SORT1 FDFT1 SLC27A3	1.66e-04	197	116	5	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TYMS TENM3 OR1A1 GJC3 STEAP1	1.66e-04	197	116	5	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACO1 PPARG SORT1 FDFT1 SLC27A3	1.66e-04	197	116	5	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MCM4 SLC28A3 CCNB1 TYMS TMEM106C	1.66e-04	197	116	5	bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TTC39B REXO5 ZNF521 ADCYAP1 CMA1	1.69e-04	198	116	5	2e6630eab77b12a6059682ab5ba465f38e469102
ToppCell	severe-Myeloid-Immature_Neutrophils_2\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	POLE MCM4 SLC28A3 TYMS TMEM106C	1.69e-04	198	116	5	844f534551483c89ef789d1cfeb4680e54f794b2
ToppCell	severe-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	POLE MCM4 SLC28A3 TYMS TMEM106C	1.69e-04	198	116	5	e36303628af3139310c1d7a84d2919b7319bbda4
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTC39B LAMA3 PPARG BMX GUCY2C	1.69e-04	198	116	5	a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TTC39B REXO5 ZNF521 ADCYAP1 CMA1	1.69e-04	198	116	5	a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating-AT2_proliferating_L.0.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MCM4 CCNB1 TYMS MALL TMEM106C	1.73e-04	199	116	5	d7dbc551c05da32c698908348572fb0ce1166e10
ToppCell	mLN-Dendritic_cell-cDC2\|mLN / Region, Cell class and subclass	GJC2 SORT1 IDO2 MMP1 MMP3	1.73e-04	199	116	5	cb17bccb47d04f7793709f9a4376fcc8ce95430c
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	POLE MCM4 TYMS MALL TMEM106C	1.73e-04	199	116	5	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MCM4 CCNB1 TYMS MALL TMEM106C	1.73e-04	199	116	5	6a89c3a65fa50af92585c52bec203bcff6f94efc
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	ACP6 POLE MCM4 TYMS TMEM106C	1.73e-04	199	116	5	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	mLN-(5)_Dendritic_cell-(50)_cDC2\|mLN / shred on region, Cell_type, and subtype	GJC2 SORT1 IDO2 MMP1 MMP3	1.73e-04	199	116	5	8d1b18596a0965427abefe0be744c74e4c11d5d3
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	ACP6 POLE MCM4 TYMS TMEM106C	1.73e-04	199	116	5	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF521 GJC2 PPARG GJA1 BMX	1.78e-04	200	116	5	76e90231aa94afc12e618da8ae314c51644acab4
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	ACP6 POLE SLC28A3 SORT1 TYMS	1.78e-04	200	116	5	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF521 GJC2 PPARG GJA1 BMX	1.78e-04	200	116	5	e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCell	mild-T/NK_proliferative\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	POLE MCM4 CCNB1 TYMS TMEM106C	1.78e-04	200	116	5	25b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	POLE MCM4 CCNB1 TYMS TMEM106C	1.78e-04	200	116	5	04bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	POLE MCM4 CCNB1 TYMS TMEM106C	1.78e-04	200	116	5	f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ACP6 POLE SORT1 TYMS BMX	1.78e-04	200	116	5	a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-4\|TCGA-Thymus / Sample_Type by Project: Shred V9	OR6C74 OR6C65 PPP1R3A CALY	1.96e-04	110	116	4	56e93e8d0d6232ab9090f685e5e4803ef79b2567
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GJC2 DCT GJC3 STEAP1	2.65e-04	119	116	4	ec3af1253f03b3ec403f73243237acf08ad56789
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	ZNF521 GJC2 GJA1 MALL	3.10e-04	124	116	4	4b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IDO2 GJA1 TENM3 ADGRD1	5.32e-04	143	116	4	27e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IDO2 GJA1 TENM3 ADGRD1	5.32e-04	143	116	4	4edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALR3 DYNC2H1 SLC28A3 TTC39A	6.85e-04	153	116	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 SIPA1L3 IDO2 CSNK2B	7.19e-04	155	116	4	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ZNF365 GJA1 BNIPL MAPK6	7.37e-04	156	116	4	ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	POLE SIDT1 GUCY2C TTC39A	7.37e-04	156	116	4	19472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE SLC28A3 TYMS PPP1R3A	7.37e-04	156	116	4	b28bbdb515317368f1231b0b15d7442352f3b400
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 KMO TENM3 CDH6	7.72e-04	158	116	4	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 KMO TENM3 CDH6	7.72e-04	158	116	4	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	severe_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	ZNF521 BNIPL TTC39A RAPGEFL1	7.91e-04	159	116	4	e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCell	severe_COVID-19-pDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	ZNF521 BNIPL TTC39A RAPGEFL1	7.91e-04	159	116	4	ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF521 GJC2 GJA1 SLC27A3	8.28e-04	161	116	4	fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE MCM4 CPA1 IDO2	8.28e-04	161	116	4	82ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJC2 GJA1 CELSR1 MALL	8.28e-04	161	116	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJC2 GJA1 CELSR1 MALL	8.28e-04	161	116	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF521 GJC2 GJA1 SLC27A3	8.28e-04	161	116	4	c53c461fc721a7960cef86662f49e2a495520701
Disease	Polycystic kidneys, severe infantile with tuberous sclerosis	TSC2 PKD1	1.23e-05	2	104	2	C1838327
Disease	INSULIN RESISTANCE, SEVERE, DIGENIC	PPARG PPP1R3A	1.23e-05	2	104	2	C4016701
Disease	Malignant neoplasm of breast	RAF1 DYNC2H1 FAM210A ACVR1 ZNF365 UBLCP1 TYMS PPP1R3A GPR180 GJA1 TENM1 MMP1 MMP3 LRBA	2.48e-05	1074	104	14	C0006142
Disease	immunoglobulin light chain amyloidosis (is_marker_for)	MMP1 MMP3	3.68e-05	3	104	2	DOID:0080933 (is_marker_for)
Disease	Ocular Hypertension	NR3C1 MMP1	3.68e-05	3	104	2	C0028840
Disease	Glaucoma, Suspect	NR3C1 MMP1	3.68e-05	3	104	2	C0017614
Disease	psoriatic arthritis (is_marker_for)	MMP1 MMP3	7.35e-05	4	104	2	DOID:9008 (is_marker_for)
Disease	Mammary Carcinoma, Human	RAF1 DYNC2H1 ACVR1 ZNF365 UBLCP1 TYMS GJA1 MMP1 MMP3	1.03e-04	525	104	9	C4704874
Disease	Mammary Neoplasms, Human	RAF1 DYNC2H1 ACVR1 ZNF365 UBLCP1 TYMS GJA1 MMP1 MMP3	1.03e-04	525	104	9	C1257931
Disease	Mammary Neoplasms	RAF1 DYNC2H1 ACVR1 ZNF365 UBLCP1 TYMS GJA1 MMP1 MMP3	1.06e-04	527	104	9	C1458155
Disease	Milroy Disease	GJC2 CELSR1	1.22e-04	5	104	2	C1704423
Disease	Breast Carcinoma	RAF1 DYNC2H1 ACVR1 ZNF365 UBLCP1 TYMS GJA1 MMP1 MMP3	1.23e-04	538	104	9	C0678222
Disease	carotid stenosis (is_implicated_in)	MMP1 MMP3	1.83e-04	6	104	2	DOID:13001 (is_implicated_in)
Disease	quinolinate measurement	KMO IDO2	2.55e-04	7	104	2	EFO_0800175
Disease	Polycystic kidney disease, type 2	PPARG PKD1	2.55e-04	7	104	2	C2751306
Disease	cataract (implicated_via_orthology)	SIPA1L3 NR3C1 FDFT1	3.28e-04	38	104	3	DOID:83 (implicated_via_orthology)
Disease	severe pre-eclampsia (is_marker_for)	ACVR1 ERAP2	3.40e-04	8	104	2	DOID:13129 (is_marker_for)
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	PPARG PKD1	3.40e-04	8	104	2	C0887850
Disease	end stage renal disease (is_implicated_in)	PPARG MMP1 MMP3	4.11e-04	41	104	3	DOID:783 (is_implicated_in)
Disease	pancreatitis (implicated_via_orthology)	CPA1 PPARG	4.36e-04	9	104	2	DOID:4989 (implicated_via_orthology)
Disease	Polycystic Kidney, Autosomal Dominant	PPARG PKD1	4.36e-04	9	104	2	C0085413
Disease	high grade glioma (implicated_via_orthology)	RAF1 POLE GJA1	5.07e-04	44	104	3	DOID:3070 (implicated_via_orthology)
Disease	abdominal obesity-metabolic syndrome (implicated_via_orthology)	PPARG GUCY2C	5.44e-04	10	104	2	DOID:0060611 (implicated_via_orthology)
Disease	glomerulosclerosis (implicated_via_orthology)	PPARG MMP1	6.63e-04	11	104	2	DOID:0050851 (implicated_via_orthology)
Disease	large artery stroke	JCAD HHAT MMP3 CDH6	6.98e-04	113	104	4	EFO_0005524
Disease	alkaline phosphatase measurement	AGPAT5 FAM210A TSC2 PPARG DCT GPR180 MAN1A2 GUSB FDFT1 PKD1 LRBA	9.14e-04	1015	104	11	EFO_0004533
Disease	matrix metalloproteinase measurement	DYNC2H1 MMP3	9.36e-04	13	104	2	EFO_0004744
Disease	Connective Tissue Diseases	ACVR1 PKD1	9.36e-04	13	104	2	C0009782
Disease	atrial fibrillation (is_implicated_in)	MMP1 MMP3	1.09e-03	14	104	2	DOID:0060224 (is_implicated_in)
Disease	polycystic kidney disease (implicated_via_orthology)	PPARG PKD1	1.09e-03	14	104	2	DOID:0080322 (implicated_via_orthology)
Disease	Malignant neoplasm of skin	POLE GJA1 CSNK2B	1.20e-03	59	104	3	C0007114
Disease	Skin Neoplasms	POLE GJA1 CSNK2B	1.20e-03	59	104	3	C0037286
Disease	thrombosis (is_implicated_in)	MMP1 MMP3	1.25e-03	15	104	2	DOID:0060903 (is_implicated_in)
Disease	Coronary Arteriosclerosis	JCAD SORT1 MMP3	1.59e-03	65	104	3	C0010054
Disease	Coronary Artery Disease	JCAD SORT1 MMP3	1.59e-03	65	104	3	C1956346
Disease	schizophrenia (implicated_via_orthology)	MAN2A2 ZNF521 KMO	1.81e-03	68	104	3	DOID:5419 (implicated_via_orthology)
Disease	matrix metalloproteinase 12 measurement	DYNC2H1 MMP3	1.81e-03	18	104	2	EFO_0010590
Disease	renal cell carcinoma (is_implicated_in)	NR3C1 MMP1 MMP3	1.88e-03	69	104	3	DOID:4450 (is_implicated_in)
Disease	Cholecystitis	TTC39B LRBA	2.02e-03	19	104	2	HP_0001082
Disease	renovascular hypertension (biomarker_via_orthology)	GJA1 CMA1	2.02e-03	19	104	2	DOID:1591 (biomarker_via_orthology)
Disease	eosinophil count	RAPGEF6 ZNF585A SIPA1L3 MCM4 ACVR1 NR3C1 PPARG THOC2 ZNF585B IFNAR2 PPP1R3A CELSR1 RAPGEFL1	2.21e-03	1488	104	13	EFO_0004842
Disease	esophagus adenocarcinoma (is_implicated_in)	MMP1 MMP3	2.47e-03	21	104	2	DOID:4914 (is_implicated_in)
Disease	Lung Neoplasms	RAF1 TYMS GJA1 SIDT2 MMP1	2.51e-03	265	104	5	C0024121
Disease	Malignant neoplasm of lung	RAF1 TYMS GJA1 SIDT2 MMP1	2.55e-03	266	104	5	C0242379
Disease	hypertrophic cardiomyopathy (is_implicated_in)	CMA1 MMP1	2.71e-03	22	104	2	DOID:11984 (is_implicated_in)
Disease	carotid artery disease (is_implicated_in)	PPARG MMP1	2.71e-03	22	104	2	DOID:3407 (is_implicated_in)
Disease	Acute Lung Injury	ACVR1 PPARG	2.71e-03	22	104	2	C0242488
Disease	primary open angle glaucoma (is_implicated_in)	ACVR1 MMP1	2.97e-03	23	104	2	DOID:1070 (is_implicated_in)
Disease	idiopathic pulmonary fibrosis (is_marker_for)	MMP1 MMP3	2.97e-03	23	104	2	DOID:0050156 (is_marker_for)
Disease	Colorectal Neoplasms	POLE PPARG TYMS GUCY2C MMP1	3.04e-03	277	104	5	C0009404
Disease	drug-induced liver injury	PPARG LRBA	3.23e-03	24	104	2	EFO_0004228
Disease	Cerebral Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0750935
Disease	Intracranial Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0750936
Disease	Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0004114
Disease	Grade I Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0205768
Disease	Mixed oligoastrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0547065
Disease	interstitial lung disease (is_marker_for)	NR3C1 CMA1	3.50e-03	25	104	2	DOID:3082 (is_marker_for)
Disease	Pilocytic Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0334583
Disease	Juvenile Pilocytic Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0280783
Disease	Diffuse Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0280785
Disease	Brain Diseases	TSC2 TYMS	3.50e-03	25	104	2	C0006111
Disease	Childhood Cerebral Astrocytoma	ACVR1 MMP3	3.50e-03	25	104	2	C0338070

Protein segments in the cluster

Peptide	Gene	Start	Entry
YYPDSLVGTDSHTTM	ACO1	196	P21399
YVHYPTISTDMLSVV	ALG11	196	Q2TAA5
STVHFKLSPTYVLYM	AFDN	626	P55196
VTVKYLRSHGYMSTP	FAM210A	211	Q96ND0
STVVGLLYHSMHYYL	ADGRD1	421	Q6QNK2
LYRPHLASDTIYQIM	BMX	631	P51813
AFISIHSYSQLLMYP	CPA1	301	P15085
HEMGSLYDYLQLTTL	ACVR1	286	Q04771
TTLHYAIYNEDIPMT	ANKRD26P1	151	Q6NSI1
GTLSSYSLVLMVLHY	TENT2	326	Q6PIY7
CTVVAILLHYIYMST	CELSR1	2531	Q9NYQ6
SYGRVLLAVYHMKSA	OR2L3	216	Q8NG85
IVLYELMTGELPYSH	RAF1	536	P04049
ISVLYDIAKGMSYLH	GUCY2C	591	P25092
YVAICKPLHYTTIMS	OR6C65	121	A6NJZ3
VLKDYIAYAHSTIMP	MCM4	686	P33991
VPSALYMGFTLYHVI	GJC3	86	Q8NFK1
AISLDTYLHTPMYLF	OR1S1	61	Q8NH92
TYLHTPMYLFLANLS	OR1S1	66	Q8NH92
QTYMDGLLHYVSVIS	LAMA3	2841	Q16787
LDSLYHGTTGILYMS	MALL	91	Q13021
KDRIHSTYMYLAGSI	GHITM	121	Q9H3K2
VISTPSVMYLGYAVH	GJC2	86	Q5T442
MYSVEDLLISHGYKL	JCAD	1	Q9P266
NTEALMYPLYHSLTD	MMP3	231	P08254
SSIPNYTYVMEHLFR	BNIPL	226	Q7Z465
HYSPIYLSFVMLLAA	FDFT1	381	P37268
LRSYHITMVTKYLIT	IDO2	356	Q6ZQW0
TAEEALSHPYMSIYS	MAPK6	306	Q16659
VLLIYLDTQLHTPMY	OR2M2	46	Q96R28
VLLIYLDTQLHTPMY	OR2M3	46	Q8NG83
VLLIYLDTQLHTPMY	OR2M5	46	A3KFT3
VLLIYLDTQLHTPMY	OR2M7	46	Q8NG81
SLHQPMYYFISILAV	OR51L1	56	Q8NGJ5
HTPAKVQLMLYTYLS	LRBA	581	P50851
MLYVSSELHRLQVSY	NR3C1	646	P04150
IAQHYGMSYLLETLE	POLE	2261	Q07864
SMVILYRLFLSHSLY	GPR180	401	Q86V85
LASLSALIYTVYTMH	OR2AG1	151	Q9H205
YVAICKPLHYTTIMS	OR2AP1	121	Q8NGE2
VSVHDPKYSLMSLVY	GREB1L	1386	Q9C091
LTEYLSTHYKAPRMV	UQCRC1	216	P31930
IVPTHYTLLYTIMSK	IFNAR2	61	P48551
YVAICKPLHYTTIMS	OR6C74	121	A6NCV1
THSFLLLVMGYDRYV	OR10H4	111	Q8NGA5
AISLDIYLHTPMYLF	OR1S2	61	Q8NGQ3
LITVYHYDLMIGLTF	PPP1R3A	1086	Q16821
HYDLMIGLTFYVLSL	PPP1R3A	1091	Q16821
HLLSVSLYYGTLIFM	OR5AC2	246	Q9NZP5
YMHAIYSSIPLLETV	HHAT	266	Q5VTY9
LLVYGIIMHSSVYSS	ADCYAP1	11	P18509
TIYHGTILFMYVRPS	OR5T1	261	Q8NG75
KAVHLLIYLTMYASS	GALR3	96	O60755
SLISSLQHMVYEYIC	DYNC2H1	3546	Q8NCM8
QHYLSYTEESLLPVM	CCNB1	366	P14635
SLIAISSTYLLIHYM	KMO	431	O15229
SSTYLLIHYMSPRSF	KMO	436	O15229
HKICTPLTLEMYYTE	CALY	121	Q9NYX4
MYSRISSSPTHSLYV	DOCK2	211	Q92608
HSRLPYLVISDGYMV	CPLANE1	406	Q9H799
HLLYSITTVSKYFMI	CDHR3	271	Q6ZTQ4
LESAGYYLKMVIAHT	GUSB	456	P08236
TYLAVIHPLRYLSFM	GPR148	146	Q8TDV2
SVPTLLYLAHVFYVM	GJA1	86	P17302
MTSHDYALPVFVYTR	HYAL4	291	Q2M3T9
AEMLYGLIHARYILT	CSNK2B	76	P67870
SYPSLLSHLTSMYLN	MAN2A2	1006	P49641
MEFIHLSYLTGDLTY	MAN1A2	341	O60476
TPLMYASYIGHDTIV	ANKS3	71	Q6ZW76
LDMTYYLQHETSSPA	ERAP2	681	Q6P179
VMLENYSHLVSVGYL	KRBOX4	36	Q5JUW0
YNRHEMSTYLLPVVI	CDH6	556	P55285
GISETYDVSPLLHYM	HEATR1	336	Q9H583
IYSLLSYMDLSVVPV	FRY	2246	Q5TBA9
TGVTIYHGTILVSYM	OR5T3	276	Q8NGG3
YHGTILVSYMRPSSS	OR5T3	281	Q8NGG3
VMHTYAAPGEYLLTV	PKD1	1091	P98161
GSHLTVVSLYYGTVM	OR1A1	241	Q9P1Q5
FYTIITHMLSPLIYT	OR4A5	271	Q8NH83
AVMHPLTYAETLIDY	CFAP221	666	Q4G0U5
YIGLMTQSSLETHHY	TMEM106C	226	Q9BVX2
LATSTHSKVLYVYDM	UTP18	311	Q9Y5J1
YRDAVMSHTLIYIPS	UTP25	606	Q68CQ4
TKMLEGPHYYTILDS	SORT1	516	Q99523
TPEDLNTIYSYLHGM	RAPGEF6	21	Q8TEU7
HIIATLLLSTQLYYM	SIDT2	641	Q8NBJ9
LSHSTDIGALMYPSY	MMP1	226	P03956
VYLMLTTHPSLYRVD	SEC24A	936	O95486
LKYGVHEIIYTMLAS	PPARG	346	P37231
DYEIMFHVSTLLPYT	SIPA1L3	691	O60292
VKSIHYLYFSMILST	SLC5A11	516	Q8WWX8
ITSLYYDLQGHLIAM	TENM1	2291	Q9UKZ4
YLPYITKSELHAIMT	SLC28A3	351	Q9HAS3
FAVLHAIYSLSYPMR	STEAP1	171	Q9UHE8
HSRPYMAYLEIVTSN	CMA1	31	P23946
ILTLMVPYYTIDTES	SLC7A14	306	Q8TBB6
SLTMYDLAVPHTSYE	THOC2	886	Q8NI27
MYHALGYSTIVVLQA	TTC39B	166	Q5VTQ0
RPVSYVQTYTAMDLH	ZNF365	121	Q70YC5
DVIYLALPLYHMSGS	SLC27A3	321	Q5K4L6
MIHPYVIDTSLLYVR	REXO5	321	Q96IC2
HVLASLALSTQIYYM	SIDT1	636	Q9NXL6
KHVTIHFMITSTYYI	ZNF521	681	Q96K83
PTAYSLLIMHRDVIY	PPAT	181	Q06203
NIASYALLTYMIAHI	TYMS	226	P04818
MLETYSHLLSVGYQV	ZNF585B	56	Q52M93
LYSGHTVMLTLTYLF	SGMS1	281	Q86VZ5
SYTYLEKSMVLLLHS	TENM3	1861	Q9P273
AMSVYTLSPEKYHAL	ACP6	401	Q9NPH0
GYTPLMETHLSSKRY	DCT	501	P40126
MLETYSHLLSVGYQV	ZNF585A	56	Q6P3V2
MLETYSSLVSLGHYI	ZNF717	51	Q9BY31
LMRPYLHEFLTSAYE	UBLCP1	161	Q8WVY7
VLHTYSMRYLLPSVV	AGPAT5	6	Q9NUQ2
YMPDHSYVTIRSRLS	RAPGEFL1	321	Q9UHV5
TKESMYHSLTYATIL	TTC39A	51	Q5SRH9
MTRIGYHISLYSLST	UBXN8	221	O00124
SVYMTLYTLTHVVLL	TMEM145	281	Q8NBT3
YTLPASHATRVYEML	TSC2	576	P49815
LYRDVMLETYGHLLS	ZNF606	86	Q8WXB4