Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of T-helper cell differentiation	SHB IRF1 NFKBIZ EP300	4.00e-06	31	72	4	GO:0045624
GeneOntologyBiologicalProcess	positive regulation of CD4-positive, alpha-beta T cell differentiation	SHB IRF1 NFKBIZ EP300	1.82e-05	45	72	4	GO:0043372
GeneOntologyBiologicalProcess	regulation of T-helper cell differentiation	SHB IRF1 NFKBIZ EP300	4.69e-05	57	72	4	GO:0045622
GeneOntologyBiologicalProcess	positive regulation of CD4-positive, alpha-beta T cell activation	SHB IRF1 NFKBIZ EP300	5.02e-05	58	72	4	GO:2000516
GeneOntologyBiologicalProcess	positive regulation of alpha-beta T cell differentiation	SHB IRF1 NFKBIZ EP300	7.40e-05	64	72	4	GO:0046638
GeneOntologyBiologicalProcess	positive regulation of cellular response to hypoxia	EP300 DNMT3A	1.19e-04	5	72	2	GO:1900039
GeneOntologyBiologicalProcess	regulation of CD4-positive, alpha-beta T cell differentiation	SHB IRF1 NFKBIZ EP300	1.24e-04	73	72	4	GO:0043370
GeneOntologyBiologicalProcess	dense core granule localization	UNC13C SYBU EIPR1	1.25e-04	28	72	3	GO:0032253
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	PPP1R9A APC2 DCTN1 CAMSAP2 EP300 PLXNB1 DMTN EPHA3 CDC42EP1	1.79e-04	579	72	9	GO:0051493
GeneOntologyBiologicalProcess	regulation of organelle organization	ATF7IP PPP1R9A APC2 DCP2 HASPIN PRICKLE2 FGFR3 DCTN1 CAMSAP2 EP300 PLXNB1 DMTN EPHA3 CDC42EP1	1.93e-04	1342	72	14	GO:0033043
GeneOntologyBiologicalProcess	secretory granule localization	UNC13C SYBU EIPR1	2.26e-04	34	72	3	GO:0032252
GeneOntologyBiologicalProcess	positive regulation of alpha-beta T cell activation	SHB IRF1 NFKBIZ EP300	2.66e-04	89	72	4	GO:0046635
GeneOntologyBiologicalProcess	T-helper cell differentiation	SHB IRF1 NFKBIZ EP300	3.02e-04	92	72	4	GO:0042093
GeneOntologyBiologicalProcess	regulation of alpha-beta T cell differentiation	SHB IRF1 NFKBIZ EP300	3.15e-04	93	72	4	GO:0046637
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	SNAP91 PTPRZ1 PPP1R9A EP300 PLXNB1 EPHA3 CPEB1 CDC42EP1	3.19e-04	494	72	8	GO:0031346
GeneOntologyBiologicalProcess	CD4-positive, alpha-beta T cell differentiation involved in immune response	SHB IRF1 NFKBIZ EP300	3.28e-04	94	72	4	GO:0002294
GeneOntologyBiologicalProcess	alpha-beta T cell differentiation involved in immune response	SHB IRF1 NFKBIZ EP300	3.42e-04	95	72	4	GO:0002293
GeneOntologyBiologicalProcess	cellular response to UV	POLA1 XPC CDC25A EP300	3.70e-04	97	72	4	GO:0034644
GeneOntologyBiologicalProcess	alpha-beta T cell activation involved in immune response	SHB IRF1 NFKBIZ EP300	3.85e-04	98	72	4	GO:0002287
GeneOntologyBiologicalProcess	regulation of CD4-positive, alpha-beta T cell activation	SHB IRF1 NFKBIZ EP300	4.16e-04	100	72	4	GO:2000514
GeneOntologyBiologicalProcess	T cell differentiation involved in immune response	SHB IRF1 NFKBIZ EP300	4.65e-04	103	72	4	GO:0002292
GeneOntologyBiologicalProcess	protein ubiquitination	KBTBD6 UBR4 RLIM NUB1 FGFR3 SOCS6 EIPR1 NEURL1B HECTD1 KBTBD7	4.93e-04	811	72	10	GO:0016567
HumanPheno	Abnormal larynx morphology	POLA1 MAX TONSL FGFR3 DCTN1 ADARB1 EP300 DNMT3A	1.02e-06	201	22	8	HP:0025423
HumanPheno	Hyperpigmentation of the skin	POLA1 MAX APC2 HPS1 IRF1 XPC FGFR3 EP300	3.91e-05	328	22	8	HP:0000953
HumanPheno	Vocal cord dysfunction	POLA1 MAX DCTN1 DNMT3A	8.87e-05	57	22	4	HP:0031801
HumanPheno	Vocal cord paralysis	POLA1 MAX DCTN1 DNMT3A	8.87e-05	57	22	4	HP:0001605
HumanPheno	Vocal cord paresis	POLA1 MAX DCTN1 DNMT3A	8.87e-05	57	22	4	HP:0001604
HumanPheno	Weakness of the vocal cords	POLA1 MAX DCTN1 DNMT3A	8.87e-05	57	22	4	HP:0001603
HumanPheno	Abnormal vocal cord morphology	POLA1 MAX DCTN1 DNMT3A	1.16e-04	61	22	4	HP:0008777
Domain	LIM1_prickle	PRICKLE3 PRICKLE2	1.47e-05	2	72	2	IPR033725
Domain	LIM3_prickle	PRICKLE3 PRICKLE2	4.39e-05	3	72	2	IPR033727
Domain	LIM2_prickle	PRICKLE3 PRICKLE2	4.39e-05	3	72	2	IPR033726
Domain	PET_prickle	PRICKLE3 PRICKLE2	4.39e-05	3	72	2	IPR033723
Domain	PET	PRICKLE3 PRICKLE2	2.18e-04	6	72	2	PF06297
Domain	PET_domain	PRICKLE3 PRICKLE2	2.18e-04	6	72	2	IPR010442
Domain	PET	PRICKLE3 PRICKLE2	2.18e-04	6	72	2	PS51303
Domain	EPL1	JADE3 BRPF1	4.04e-04	8	72	2	PF10513
Domain	Enhancer_polycomb-like_N	JADE3 BRPF1	4.04e-04	8	72	2	IPR019542
Domain	SAM_2	PPP1R9A DGKH EPHA3	6.07e-04	43	72	3	PF07647
Domain	C1_1	KSR1 UNC13C DGKH	1.38e-03	57	72	3	PF00130
Domain	Pkinase_Tyr	KSR1 HASPIN FGFR3 EPHA3	1.55e-03	129	72	4	PF07714
Domain	ZF_DAG_PE_1	KSR1 UNC13C DGKH	1.93e-03	64	72	3	PS00479
Domain	ZF_DAG_PE_2	KSR1 UNC13C DGKH	1.93e-03	64	72	3	PS50081
Domain	Ser-Thr/Tyr_kinase_cat_dom	KSR1 HASPIN FGFR3 EPHA3	1.99e-03	138	72	4	IPR001245
Domain	C1	KSR1 UNC13C DGKH	2.02e-03	65	72	3	SM00109
Domain	PE/DAG-bd	KSR1 UNC13C DGKH	2.11e-03	66	72	3	IPR002219
Domain	PWWP	BRPF1 DNMT3A	2.66e-03	20	72	2	SM00293
Domain	EPHD	JADE3 BRPF1	3.22e-03	22	72	2	PS51805
Domain	PWWP	BRPF1 DNMT3A	3.52e-03	23	72	2	PF00855
Domain	PWWP_dom	BRPF1 DNMT3A	3.52e-03	23	72	2	IPR000313
Domain	PWWP	BRPF1 DNMT3A	3.83e-03	24	72	2	PS50812
Domain	Bromodomain_CS	BRPF1 EP300	4.49e-03	26	72	2	IPR018359
Domain	-	SNAP91 RPRD2	4.49e-03	26	72	2	1.25.40.90
Domain	SAM	PPP1R9A DGKH EPHA3	4.77e-03	88	72	3	SM00454
Domain	ENTH_VHS	SNAP91 RPRD2	5.56e-03	29	72	2	IPR008942
Domain	SAM_DOMAIN	PPP1R9A DGKH EPHA3	5.90e-03	95	72	3	PS50105
Domain	SAM	PPP1R9A DGKH EPHA3	6.25e-03	97	72	3	IPR001660
Domain	SH2	SHB SOCS6 TNS1	6.99e-03	101	72	3	PF00017
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KSR1 SYNJ2 SH3PXD2A DCP2 CCSER2 NUB1 SRRM2 HECTD1 CAMSAP2 ARHGAP21 CIC DMTN CDC42EP1	2.63e-08	861	73	13	36931259
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	UBR4 PRICKLE2 NUB1 SYBU SOCS6 GOLGA5 SRRM2	6.19e-07	233	73	7	37704626
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SNAP91 FAM120C ATF7IP PPP1R9A NCAN UBR4 APC2 GRIN2D DCTN1 CAMSAP2 TNS1 ARHGAP21	7.39e-07	963	73	12	28671696
Pubmed	A human MAP kinase interactome.	SYNJ2 ATF7IP MAX MUC12 DCTN1 TNS1 CIC EP300 CDC42EP1	8.30e-07	486	73	9	20936779
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	SNAP91 SYBU SRRM2 CAMSAP2 RTN2 CIC CDC42EP1	8.91e-07	246	73	7	15345747
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	POLA1 MAX UBR4 RLIM SMG9 MECOM MUC12 EIPR1 CDC25A HECTD1 DCTN1 EP300 CPEB1	3.51e-06	1327	73	13	32694731
Pubmed	Max is acetylated by p300 at several nuclear localization residues.	MAX EP300	4.35e-06	2	73	2	17217336
Pubmed	Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300.	IRF1 EP300	4.35e-06	2	73	2	10438822
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ERICH1 JADE3 POLA1 NKAPD1 MAX BRPF1 XPC CIC DNMT3A	5.16e-06	608	73	9	36089195
Pubmed	Human transcription factor protein interaction networks.	KBTBD6 ATF7IP MAX UBR4 NFKBIB RLIM MECOM IRF1 RPRD2 SRRM2 CIC EP300 CPEB1	7.81e-06	1429	73	13	35140242
Pubmed	Exploring the FGFR3-related oncogenic mechanism in bladder cancer using bioinformatics strategy.	POLA1 FGFR3	1.30e-05	3	73	2	28320388
Pubmed	Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation.	IRF1 EP300	1.30e-05	3	73	2	14662860
Pubmed	The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.	MECOM DNMT3A	1.30e-05	3	73	2	21695170
Pubmed	The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment.	KBTBD6 KBTBD7	1.30e-05	3	73	2	32572597
Pubmed	EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.	MECOM DNMT3A	1.30e-05	3	73	2	33082307
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	PRICKLE3 MAX BRPF1 RLIM TONSL IRF1 NFKBIZ CIC EP300 DNMT3A	1.46e-05	877	73	10	20211142
Pubmed	Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53.	IRF1 EP300	2.60e-05	4	73	2	15509808
Pubmed	Expression of phosphacan and neurocan during early development of mouse retinofugal pathway.	PTPRZ1 NCAN	2.60e-05	4	73	2	15283989
Pubmed	Coactivator p300 acetylates the interferon regulatory factor-2 in U937 cells following phorbol ester treatment.	IRF1 EP300	2.60e-05	4	73	2	11304541
Pubmed	Dynamic spatiotemporal expression patterns of neurocan and phosphacan indicate diverse roles in the developing and adult mouse olfactory system.	PTPRZ1 NCAN	2.60e-05	4	73	2	10861539
Pubmed	p300, but not PCAF, collaborates with IRF-1 in stimulating TRIM22 expression independently of its histone acetyltransferase activity.	IRF1 EP300	2.60e-05	4	73	2	23670564
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ATF7IP UBR4 MECOM GOLGA5 DCTN1 ARHGAP21 CIC	2.84e-05	418	73	7	34709266
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	SNAP91 FAM120C NCAN APC2 PRICKLE2 CAMSAP2 ARHGAP21	3.39e-05	430	73	7	32581705
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KSR1 SH3PXD2A PPP1R9A CCSER2 HECTD1 DMTN CDC42EP1	4.28e-05	446	73	7	24255178
Pubmed	Repression of p15INK4b expression by Myc through association with Miz-1.	MAX EP300	4.33e-05	5	73	2	11283613
Pubmed	Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons.	NCAN EPHA3	4.33e-05	5	73	2	29670169
Pubmed	Six lysine residues on c-Myc are direct substrates for acetylation by p300.	MAX EP300	4.33e-05	5	73	2	16126174
Pubmed	High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule.	PTPRZ1 NCAN	4.33e-05	5	73	2	9507007
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	PRICKLE3 UBR4 CCNO DGKH GRIN2D SRRM2 HECTD1 EP300	5.85e-05	639	73	8	23443559
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 SYNJ2 FAM120C SH3PXD2A PPP1R9A SHB RPRD2 DGKH EIPR1 HECTD1 ADARB1 EP300	5.93e-05	1489	73	12	28611215
Pubmed	Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.	BRPF1 EP300	6.48e-05	6	73	2	19001415
Pubmed	SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.	MAX EP300	6.48e-05	6	73	2	17157259
Pubmed	Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice.	PTPRZ1 NCAN	6.48e-05	6	73	2	9593903
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPRZ1 PPP4R2 PPP1R9A GOLGA5 CDC25A SRRM2 C2CD4C TNS1 CIC CDC42EP1	6.63e-05	1049	73	10	27880917
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 SYNJ2 SRRM2 CIC	7.01e-05	104	73	4	9205841
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NKAPD1 PPP4R2 HPS1 RLIM CCSER2 NFKBIZ DCTN1 TNS1 ARHGAP21 PLXNB1	8.70e-05	1084	73	10	11544199
Pubmed	Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.	KBTBD6 KBTBD7	9.06e-05	7	73	2	33990333
Pubmed	A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A.	CDC25A EP300	9.06e-05	7	73	2	27462461
Pubmed	Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.	PTPRZ1 NCAN	9.06e-05	7	73	2	21976490
Pubmed	Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription.	MAX EP300	9.06e-05	7	73	2	16287840
Pubmed	Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.	EP300 DNMT3A	9.06e-05	7	73	2	24374650
Pubmed	Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex.	PTPRZ1 NCAN	9.06e-05	7	73	2	14757526
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	KBTBD6 MAX TONSL KBTBD7 EP300	1.09e-04	223	73	5	33187986
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	KSR1 PRPF40B FAM120C MAX BRPF1 MECOM XPC SRRM2 EP300 CDC42EP1	1.10e-04	1116	73	10	31753913
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	KSR1 JADE3 SH3PXD2A NKAPD1 FGFR3 DCTN1 TNS1 ARHGAP21 EP300	1.20e-04	910	73	9	36736316
Pubmed	Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.	UBR4 DCTN1	1.21e-04	8	73	2	37871017
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PTPRZ1 PRICKLE2 GRIN2D SRRM2 DMTN	1.29e-04	231	73	5	16452087
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	KSR1 MAX HASPIN FGFR3 SOCS6 KBTBD7	1.34e-04	372	73	6	22939624
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	PRICKLE3 PRICKLE2 FGFR3	1.35e-04	47	73	3	33141892
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ERICH1 SYNJ2 SMG9 MECOM RPRD2 NUB1 GOLGA5 HECTD1	1.51e-04	733	73	8	34672954
Pubmed	The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.	EP300 DNMT3A	1.55e-04	9	73	2	18241125
Pubmed	Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.	UBR4 XPC HECTD1	1.62e-04	50	73	3	17550899
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SNAP91 FAM120C PTPRZ1 PPP1R9A NCAN PRICKLE2 DCTN1 CAMSAP2 TNS1 ARHGAP21 DMTN	1.88e-04	1431	73	11	37142655
Pubmed	Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1).	IRF1 EP300	1.93e-04	10	73	2	37023208
Pubmed	Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.	PTPRZ1 NCAN	1.93e-04	10	73	2	9184108
Pubmed	EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis.	MAX EP300	1.93e-04	10	73	2	35210568
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	PPP1R9A SHB GOLGA5 ARHGAP21 PLXNB1 EPHA3 CDC42EP1	1.94e-04	569	73	7	30639242
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SNAP91 SH3PXD2A PPP1R9A UBR4 SHB CCNO ATP10B XPC DCTN1 CAMSAP2 ARHGAP21	2.01e-04	1442	73	11	35575683
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ERICH1 PRPF40B SH3PXD2A POLA1 NCAN TONSL MECOM NUB1 NEURL1B EP300	2.20e-04	1215	73	10	15146197
Pubmed	Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.	UBR4 RLIM DCTN1	2.27e-04	56	73	3	27103069
Pubmed	CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.	KBTBD6 KBTBD7	2.36e-04	11	73	2	25684205
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PPP1R9A SHB GOLGA5 ARHGAP21 EPHA3 CDC42EP1	2.61e-04	421	73	6	36976175
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	SH3PXD2A MAX MECOM DGKH NUB1 GRIN2D NEURL1B ADARB1 DNMT3A	2.82e-04	1021	73	9	26760575
Pubmed	Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase.	RLIM HECTD1	2.83e-04	12	73	2	34611473
Pubmed	Phenotypic annotation of the mouse X chromosome.	JADE3 POLA1 RLIM	2.93e-04	61	73	3	20548051
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	KSR1 PTPRZ1 FGFR3 CDC25A EP300	2.94e-04	276	73	5	28319085
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SNAP91 CCSER2 SYBU DCTN1	2.94e-04	151	73	4	17043677
Pubmed	UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.	UBR4 RLIM KBTBD7	3.07e-04	62	73	3	18775313
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	KSR1 PRICKLE3 JADE3 MAX NFKBIB RPRD2 CAMSAP2 ARHGAP21 CDC42EP1	3.18e-04	1038	73	9	26673895
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PPP4R2 HASPIN CCSER2 SMG9 RPRD2 HECTD1	3.30e-04	440	73	6	34244565
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBR4 NUB1 HECTD1	3.69e-04	66	73	3	24811749
Pubmed	Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.	KSR1 SHB MUC12 CIC EP300	3.86e-04	293	73	5	31741433
Pubmed	Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.	NFKBIB EP300	3.89e-04	14	73	2	11500849
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KBTBD6 JADE3 TONSL MECOM XPC EP300 DNMT3A	4.13e-04	645	73	7	25281560
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SYNJ2 JADE3 BRPF1 SHB GOLGA5 DCTN1 CAMSAP2 ARHGAP21	4.17e-04	853	73	8	28718761
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MAX UBR4 MECOM CDC25A DCTN1 KBTBD7 CIC EP300	4.30e-04	857	73	8	25609649
Pubmed	PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.	MAX EP300	4.48e-04	15	73	2	15674325
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	PTPRZ1 NCAN	4.48e-04	15	73	2	38871984
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	SHB SOCS6 TNS1	4.97e-04	73	73	3	24728074
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	CCNO ATP10B NEURL1B	5.37e-04	75	73	3	15372022
Pubmed	Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.	SHB SOCS6 TNS1	5.80e-04	77	73	3	22973453
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	KSR1 POLA1 UBR4 RLIM RPRD2 CIC DNMT3A	6.10e-04	689	73	7	36543142
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	KRBA1 MECOM RPRD2 CAMSAP2	6.21e-04	184	73	4	32908313
Pubmed	Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.	MAX FGFR3	6.51e-04	18	73	2	8521822
Pubmed	A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein.	MAX IRF1	6.51e-04	18	73	2	20599664
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	BRPF1 FGFR3 NEURL1B DCTN1 EP300	6.79e-04	332	73	5	37433992
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	POLA1 PPP4R2 RPRD2 SRRM2 DCTN1 CIC	6.88e-04	506	73	6	30890647
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	MAX DCTN1 CAMSAP2 ARHGAP21	7.14e-04	191	73	4	20195357
Pubmed	Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain.	MAX DNMT3A	7.26e-04	19	73	2	23665319
Pubmed	Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.	PTPRZ1 CAMSAP2	8.06e-04	20	73	2	31277925
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SYNJ2 FAM120C SH3PXD2A POLA1 BRPF1 SMG9 XPC	8.16e-04	724	73	7	36232890
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	SNAP91 SH3PXD2A PRICKLE2 SRRM2 DMTN	8.28e-04	347	73	5	17114649
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SNAP91 UBR4 CIC	8.29e-04	87	73	3	12465718
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	SNAP91 PTPRZ1 NCAN DCTN1	8.79e-04	202	73	4	33601422
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	POLA1 DCP2 CDC42EP1	8.85e-04	89	73	3	23891004
Pubmed	KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.	JADE3 BRPF1	8.89e-04	21	73	2	27270040
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	RPRD2 FGFR3 SRRM2 EP300 EPHA3	9.52e-04	358	73	5	32460013
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	KBTBD6 MAX BRPF1 HECTD1 DCTN1	9.64e-04	359	73	5	35559673
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	PPP1R9A RPRD2 SRRM2 CAMSAP2 ARHGAP21	9.88e-04	361	73	5	30344098
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	MAX UBR4 RLIM HECTD1	1.05e-03	212	73	4	33853758
Interaction	YWHAH interactions	KSR1 PRICKLE3 SYNJ2 SH3PXD2A CCSER2 NUB1 SOCS6 CDC25A SRRM2 HECTD1 DCTN1 CAMSAP2 ARHGAP21 CIC DMTN CPEB1 CDC42EP1	2.41e-07	1102	72	17	int:YWHAH
Interaction	YWHAB interactions	KSR1 PRICKLE3 SYNJ2 SH3PXD2A CCSER2 NUB1 FGFR3 CDC25A SRRM2 HECTD1 DCTN1 CAMSAP2 ARHGAP21 CIC DMTN CDC42EP1	4.32e-07	1014	72	16	int:YWHAB
Interaction	POLR1G interactions	JADE3 ATF7IP BRPF1 UBR4 NFKBIB RPRD2 XPC SRRM2 HECTD1 CIC DNMT3A	1.22e-06	489	72	11	int:POLR1G
Interaction	YWHAG interactions	KSR1 PRICKLE3 SYNJ2 SH3PXD2A DCP2 SHB CCSER2 NUB1 SOCS6 CDC25A SRRM2 HECTD1 CAMSAP2 ARHGAP21 CIC DMTN CDC42EP1	1.37e-06	1248	72	17	int:YWHAG
Interaction	ZBTB21 interactions	KSR1 PRICKLE3 SH3PXD2A DACT3 CAMSAP2 KBTBD7 CIC	1.74e-06	161	72	7	int:ZBTB21
Interaction	XRCC5 interactions	POLA1 MAX BRPF1 RLIM TONSL MECOM XPC GOLGA5 HECTD1 CIC EP300	2.02e-06	515	72	11	int:XRCC5
Interaction	LIMA1 interactions	KSR1 SH3PXD2A POLA1 PPP1R9A RLIM HASPIN CAMSAP2 ADARB1 ARHGAP21 CIC	2.84e-06	429	72	10	int:LIMA1
Interaction	MACROH2A1 interactions	NKAPD1 MAX RLIM TONSL MECOM XPC FGFR3 HECTD1 ADARB1 DNMT3A	5.07e-06	458	72	10	int:MACROH2A1
Interaction	SSRP1 interactions	JADE3 POLA1 BRPF1 TONSL MECOM RPRD2 XPC SRRM2 HECTD1 ADARB1 CIC EP300	5.12e-06	685	72	12	int:SSRP1
Interaction	SFN interactions	KSR1 SYNJ2 SH3PXD2A CCSER2 NUB1 CDC25A SRRM2 HECTD1 CAMSAP2 ARHGAP21 DMTN CDC42EP1	5.68e-06	692	72	12	int:SFN
Interaction	DCLK1 interactions	KSR1 SH3PXD2A PPP1R9A DCTN1 CAMSAP2 CIC	6.18e-06	127	72	6	int:DCLK1
Interaction	ZBTB17 interactions	MAX RLIM CIC EP300 DNMT3A	8.18e-06	77	72	5	int:ZBTB17
Interaction	MYO6 interactions	FAM120C PPP1R9A APC2 RLIM CCSER2 RPRD2 FGFR3 SRRM2 DCTN1	1.18e-05	398	72	9	int:MYO6
Interaction	MAPRE3 interactions	SYNJ2 APC2 CCSER2 SYBU DCTN1 CAMSAP2 ARHGAP21	1.81e-05	230	72	7	int:MAPRE3
Interaction	CDC25C interactions	KSR1 SH3PXD2A CDC25A HECTD1 CAMSAP2 EP300	2.00e-05	156	72	6	int:CDC25C
Interaction	PIAS3 interactions	ATF7IP PRICKLE2 IRF1 ARHGAP21 EP300	2.28e-05	95	72	5	int:PIAS3
Interaction	TFPT interactions	KRBA1 KBTBD6 MAX EIPR1 GOLGA5 KBTBD7	2.31e-05	160	72	6	int:TFPT
Interaction	MTERF1 interactions	MAX DCTN1 ADARB1	2.87e-05	17	72	3	int:MTERF1
Interaction	YWHAE interactions	KSR1 PRICKLE3 SYNJ2 SH3PXD2A CCSER2 NUB1 CDC25A SRRM2 HECTD1 DCTN1 CAMSAP2 ARHGAP21 CIC DMTN CDC42EP1	3.05e-05	1256	72	15	int:YWHAE
Interaction	CAMSAP2 interactions	KSR1 SNAP91 SH3PXD2A DCTN1 CAMSAP2 KBTBD7	3.15e-05	169	72	6	int:CAMSAP2
Interaction	ARHGEF2 interactions	PPP1R9A PRICKLE2 MECOM HECTD1 DCTN1 CAMSAP2 ARHGAP21	3.58e-05	256	72	7	int:ARHGEF2
Interaction	UPF1 interactions	FAM120C DCP2 SMG9 MECOM RPRD2 HECTD1 DCTN1 ADARB1 EP300 CPEB1	3.95e-05	581	72	10	int:UPF1
Interaction	GIGYF1 interactions	KSR1 FAM120C SH3PXD2A DACT3 CAMSAP2 CPEB1	4.08e-05	177	72	6	int:GIGYF1
Interaction	H4C12 interactions	RLIM TONSL XPC CIC	4.14e-05	54	72	4	int:H4C12
Interaction	H4C9 interactions	RLIM TONSL XPC CIC EP300	4.23e-05	108	72	5	int:H4C9
Interaction	YWHAZ interactions	KSR1 PRICKLE3 SH3PXD2A CCSER2 NUB1 CDC25A HECTD1 DCTN1 CAMSAP2 TNS1 ARHGAP21 CIC EP300 DMTN CDC42EP1	5.36e-05	1319	72	15	int:YWHAZ
Interaction	GTF2I interactions	NFKBIB RLIM MECOM CDC25A SRRM2 ADARB1 CIC EP300	5.44e-05	373	72	8	int:GTF2I
Interaction	ALX3 interactions	KBTBD6 XPC KBTBD7	6.41e-05	22	72	3	int:ALX3
Interaction	RCOR1 interactions	MAX UBR4 MECOM SOCS6 EIPR1 GOLGA5 DCTN1 ARHGAP21 CIC	6.42e-05	494	72	9	int:RCOR1
Interaction	SRGAP2 interactions	KSR1 SH3PXD2A PRICKLE2 HECTD1 CAMSAP2 ARHGAP21	7.39e-05	197	72	6	int:SRGAP2
Interaction	MAPRE1 interactions	SYNJ2 APC2 CCSER2 SYBU SRRM2 DCTN1 CAMSAP2 ARHGAP21 EP300	8.70e-05	514	72	9	int:MAPRE1
Interaction	STARD13 interactions	KSR1 SH3PXD2A PRICKLE2 ARHGAP21	1.03e-04	68	72	4	int:STARD13
Interaction	H4C6 interactions	RLIM TONSL XPC CIC	1.09e-04	69	72	4	int:H4C6
Interaction	AMOT interactions	UBR4 RLIM CCSER2 SOCS6 HECTD1 CAMSAP2 EP300	1.24e-04	312	72	7	int:AMOT
Interaction	ZNF738 interactions	KRBA1 HECTD1	1.25e-04	5	72	2	int:ZNF738
Interaction	EHMT2 interactions	ATF7IP MAX MECOM CDC25A CIC EP300 DNMT3A	1.32e-04	315	72	7	int:EHMT2
Interaction	THOC2 interactions	NCAN MECOM HECTD1 ADARB1 KBTBD7 CIC	1.32e-04	219	72	6	int:THOC2
Interaction	CKAP2L interactions	HECTD1 DCTN1 CAMSAP2	1.34e-04	28	72	3	int:CKAP2L
Interaction	AHNAK interactions	JADE3 SH3PXD2A PPP1R9A HASPIN ADARB1 ARHGAP21 CDC42EP1	1.40e-04	318	72	7	int:AHNAK
Interaction	AP2M1 interactions	KBTBD6 SNAP91 NKAPD1 MECOM SOCS6 HECTD1 KBTBD7 EP300	1.46e-04	430	72	8	int:AP2M1
Interaction	YWHAQ interactions	KSR1 SYNJ2 SH3PXD2A CCSER2 NUB1 SOCS6 CDC25A HECTD1 CAMSAP2 ARHGAP21 CIC DMTN CDC42EP1	1.47e-04	1118	72	13	int:YWHAQ
Interaction	TERF2IP interactions	ERICH1 KBTBD6 POLA1 ATF7IP SRRM2 HECTD1 KBTBD7 CIC DNMT3A	1.49e-04	552	72	9	int:TERF2IP
Interaction	POLR1D interactions	PPP1R9A NFKBIB RPRD2 SYBU CDC25A	1.50e-04	141	72	5	int:POLR1D
Interaction	EXOC1 interactions	CCSER2 SYBU EIPR1 GOLGA5 HECTD1	1.60e-04	143	72	5	int:EXOC1
Interaction	CDK12 interactions	KSR1 MAX SRRM2 HECTD1 ADARB1 EP300	1.65e-04	228	72	6	int:CDK12
Interaction	AFDN interactions	KSR1 PRICKLE3 SH3PXD2A PPP1R9A SHB SOCS6 ARHGAP21	1.85e-04	333	72	7	int:AFDN
Interaction	EEF1D interactions	MAX HASPIN SRRM2 CAMSAP2 ADARB1 ARHGAP21 EP300	1.85e-04	333	72	7	int:EEF1D
Interaction	NADK interactions	KSR1 SH3PXD2A CAMSAP2 EP300	1.93e-04	80	72	4	int:NADK
Interaction	PLCD4 interactions	KBTBD6 BRPF1 KBTBD7	2.01e-04	32	72	3	int:PLCD4
Interaction	CDC25A interactions	PPP4R2 NFKBIB FGFR3 CDC25A EP300	2.06e-04	151	72	5	int:CDC25A
Interaction	SF3A3 interactions	PRPF40B NKAPD1 SRRM2 DCTN1 ADARB1 CIC EP300	2.10e-04	340	72	7	int:SF3A3
Interaction	PHF21A interactions	MAX UBR4 MECOM EIPR1 GOLGA5 ARHGAP21 CIC	2.22e-04	343	72	7	int:PHF21A
Interaction	FOSL2 interactions	KBTBD6 MECOM KBTBD7 EP300	2.22e-04	83	72	4	int:FOSL2
Interaction	SMARCA4 interactions	MECOM IRF1 XPC SRRM2 HECTD1 ADARB1 CIC EP300	2.38e-04	462	72	8	int:SMARCA4
Interaction	USF1 interactions	MAX UBR4 CIC EP300	2.44e-04	85	72	4	int:USF1
Interaction	CDK1 interactions	POLA1 PPP4R2 HASPIN CCNO FGFR3 CDC25A HECTD1 CIC EP300	2.45e-04	590	72	9	int:CDK1
Interaction	EDC3 interactions	KSR1 SH3PXD2A DCP2 EP300 CPEB1	2.78e-04	161	72	5	int:EDC3
Interaction	HNRNPU interactions	FAM120C PPP4R2 MAX RLIM MECOM GRIN2D SRRM2 HECTD1 DCTN1 ARHGAP21 CIC EP300	2.80e-04	1035	72	12	int:HNRNPU
Interaction	PPP1CC interactions	MAX PPP1R9A RLIM RPRD2 SRRM2 CAMSAP2 TNS1 ARHGAP21 CIC EP300	2.81e-04	738	72	10	int:PPP1CC
Interaction	PHF6 interactions	MECOM FGFR3 HECTD1 ARHGAP21 EP300	2.86e-04	162	72	5	int:PHF6
Interaction	DDX50 interactions	SRRM2 HECTD1 ADARB1 CIC EP300 CPEB1	3.14e-04	257	72	6	int:DDX50
Interaction	TAF1 interactions	KSR1 MAX BRPF1 HECTD1 CIC CDC42EP1	3.34e-04	260	72	6	int:TAF1
Interaction	H3C1 interactions	POLA1 BRPF1 UBR4 RLIM TONSL HASPIN MECOM IRF1 XPC EP300 DNMT3A	3.34e-04	901	72	11	int:H3C1
Interaction	CT45A2 interactions	PPP4R2 HECTD1	3.48e-04	8	72	2	int:CT45A2
Interaction	CSNK2B interactions	ERICH1 JADE3 NKAPD1 BRPF1 MECOM IRF1 XPC CIC EP300	3.74e-04	625	72	9	int:CSNK2B
Interaction	H3C3 interactions	JADE3 NKAPD1 BRPF1 RLIM TONSL XPC CIC DNMT3A	3.78e-04	495	72	8	int:H3C3
Interaction	CDH1 interactions	SYNJ2 MAX SHB CCSER2 GOLGA5 HECTD1 ARHGAP21 EP300 DNMT3A CDC42EP1	3.85e-04	768	72	10	int:CDH1
Interaction	KIF1B interactions	KSR1 FAM120C SH3PXD2A DCTN1 CPEB1	3.87e-04	173	72	5	int:KIF1B
Interaction	SIRT6 interactions	PPP4R2 TONSL HASPIN CCSER2 SMG9 RPRD2 XPC HECTD1 EP300	3.87e-04	628	72	9	int:SIRT6
Interaction	H3C11 interactions	RLIM TONSL XPC	3.93e-04	40	72	3	int:H3C11
Interaction	SIN3A interactions	MAX UBR4 RLIM HECTD1 ADARB1 CIC EP300	4.12e-04	380	72	7	int:SIN3A
Interaction	MPG interactions	RPRD2 HECTD1 CIC EP300	4.20e-04	98	72	4	int:MPG
Interaction	EPB41L3 interactions	PRICKLE3 HASPIN MECOM SRRM2 HECTD1 CIC	4.24e-04	272	72	6	int:EPB41L3
Interaction	XRCC6 interactions	MAX RLIM TONSL MECOM RPRD2 XPC SRRM2 HECTD1 ADARB1 CIC EP300	4.29e-04	928	72	11	int:XRCC6
Interaction	H4C14 interactions	RLIM XPC CIC EP300	4.71e-04	101	72	4	int:H4C14
Interaction	CBX3 interactions	ERICH1 JADE3 ATF7IP MAX MECOM XPC SRRM2 CIC EP300	4.75e-04	646	72	9	int:CBX3
Interaction	KDM1A interactions	ATF7IP MAX UBR4 MECOM SOCS6 GOLGA5 DCTN1 ADARB1 ARHGAP21 CIC EP300	4.82e-04	941	72	11	int:KDM1A
Interaction	H3C12 interactions	RLIM TONSL XPC	4.87e-04	43	72	3	int:H3C12
Interaction	CBY1 interactions	KSR1 SH3PXD2A DACT3 XPC CAMSAP2	4.88e-04	182	72	5	int:CBY1
Interaction	CLOCK interactions	MAX EIPR1 GOLGA5 EP300	4.89e-04	102	72	4	int:CLOCK
Interaction	MEAF6 interactions	KBTBD6 JADE3 MAX BRPF1	5.26e-04	104	72	4	int:MEAF6
Interaction	POTEI interactions	RLIM RPRD2 FGFR3 ADARB1	5.45e-04	105	72	4	int:POTEI
Interaction	NOG interactions	KBTBD6 SRRM2 KBTBD7	5.57e-04	45	72	3	int:NOG
Interaction	MCM6 interactions	PPP4R2 TONSL CDC25A SRRM2 DCTN1 EP300	5.63e-04	287	72	6	int:MCM6
Interaction	NCKAP5L interactions	MAX EIPR1 GOLGA5 DCTN1	5.65e-04	106	72	4	int:NCKAP5L
Interaction	GTF2H1 interactions	ATF7IP BRPF1 CCSER2 XPC	5.86e-04	107	72	4	int:GTF2H1
Interaction	BTBD8 interactions	DCTN1 CAMSAP2 ARHGAP21	5.94e-04	46	72	3	int:BTBD8
Interaction	EGLN3 interactions	PRICKLE3 UBR4 DCP2 TONSL SHB CCSER2 NUB1 CDC25A HECTD1 DCTN1 CAMSAP2 ARHGAP21 CDC42EP1	6.12e-04	1296	72	13	int:EGLN3
Interaction	CAVIN1 interactions	KBTBD6 MAX MECOM GOLGA5 KBTBD7 ARHGAP21	6.16e-04	292	72	6	int:CAVIN1
Interaction	HMMR interactions	HECTD1 DCTN1 CAMSAP2 EP300	6.28e-04	109	72	4	int:HMMR
Interaction	SMARCA5 interactions	MAX RLIM MECOM FGFR3 HECTD1 ADARB1 CIC	6.95e-04	415	72	7	int:SMARCA5
Interaction	PPP4R2 interactions	PPP4R2 CDC25A SRRM2 DCTN1	7.19e-04	113	72	4	int:PPP4R2
Interaction	CENPU interactions	HECTD1 ADARB1 EP300 PLXNB1	7.19e-04	113	72	4	int:CENPU
Interaction	ACIN1 interactions	SNAP91 NKAPD1 SRRM2 HECTD1 ADARB1 CIC	7.22e-04	301	72	6	int:ACIN1
Interaction	SENP3 interactions	SNAP91 ATF7IP RLIM TONSL HECTD1 EP300	7.22e-04	301	72	6	int:SENP3
Interaction	SMC1A interactions	POLA1 MECOM FGFR3 HECTD1 ADARB1 CIC EP300	7.25e-04	418	72	7	int:SMC1A
Interaction	H4C3 interactions	RLIM TONSL CIC	7.60e-04	50	72	3	int:H4C3
Interaction	ACTC1 interactions	POLA1 PPP4R2 RLIM RPRD2 SRRM2 DCTN1 ADARB1 CIC DMTN	7.93e-04	694	72	9	int:ACTC1
Interaction	SLC25A10 interactions	DCP2 SOCS6 ADARB1 CIC EP300	7.99e-04	203	72	5	int:SLC25A10
Interaction	MAP9 interactions	DCTN1 CAMSAP2 EP300	8.05e-04	51	72	3	int:MAP9
Cytoband	13q14.11	KBTBD6 DGKH KBTBD7	3.38e-05	39	73	3	13q14.11
Cytoband	7q36	KRBA1 NUB1	8.53e-04	27	73	2	7q36
GeneFamily	Prickle planar cell polarity proteins\|LIM domain containing	PRICKLE3 PRICKLE2	4.48e-05	4	50	2	1184
GeneFamily	CD molecules\|Mucins	MUC12 MUC22	1.52e-03	21	50	2	648
GeneFamily	PWWP domain containing	BRPF1 DNMT3A	1.67e-03	22	50	2	1147
GeneFamily	Sterile alpha motif domain containing	PPP1R9A DGKH EPHA3	1.85e-03	88	50	3	760
GeneFamily	SH2 domain containing	SHB SOCS6 TNS1	2.74e-03	101	50	3	741
GeneFamily	Ankyrin repeat domain containing	NFKBIB TONSL NFKBIZ HECTD1	4.45e-03	242	50	4	403
GeneFamily	Fibronectin type III domain containing	PTPRZ1 ATF7IP EPHA3	9.83e-03	160	50	3	555
GeneFamily	LIM domain containing	PRICKLE3 PRICKLE2	1.16e-02	59	50	2	1218
Coexpression	GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN	ERICH1 SYNJ2 JADE3 IRF1 NUB1 CPEB1	1.87e-05	197	73	6	M9708
Coexpression	GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN	KSR1 NFKBIB IRF1 NFKBIZ SYBU CDC25A	1.98e-05	199	73	6	M9749
Coexpression	GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN	KRBA1 NFKBIB TONSL SHB NEURL1B CAMSAP2	2.04e-05	200	73	6	M330
Coexpression	BUSSLINGER_GASTRIC_PREZYMOGENIC_CELLS	PTPRZ1 MECOM NFKBIZ SRRM2	2.40e-05	60	73	4	M40007
Coexpression	DESCARTES_MAIN_FETAL_GRANULE_NEURONS	SYNJ2 CCSER2 UNC13C	3.07e-05	22	73	3	M40087
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	KBTBD6 SNAP91 SH3PXD2A PPP1R9A NCAN APC2 DACT3 PRICKLE2 SYBU CAMSAP2 DMTN EPHA3	5.11e-05	1106	73	12	M39071
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRZ1 PPP1R9A CCNO MECOM FGFR3 SYBU	8.97e-07	198	73	6	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRZ1 PPP1R9A CCNO MECOM FGFR3 SYBU	8.97e-07	198	73	6	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PTPRZ1 SH3PXD2A DGKH FGFR3 HECTD1 PLXNB1	9.51e-07	200	73	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	PRPF40B ATF7IP PPP1R9A RPRD2 PLXNB1	7.89e-06	166	73	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ERICH1 JADE3 NUB1 C2CD4C CPEB1	9.12e-06	171	73	5	ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KSR1 SH3PXD2A ATP10B DGKH ARHGAP21	1.14e-05	179	73	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PRPF40B SOCS6 ADARB1 RTN2	1.27e-05	183	73	5	ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP4R2 RLIM NFKBIZ CAMSAP2 ADARB1	1.33e-05	185	73	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	PTPRZ1 SHB MECOM FGFR3 PLXNB1	1.40e-05	187	73	5	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	PTPRZ1 PPP1R9A CCNO MECOM FGFR3	1.48e-05	189	73	5	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DACT3 NFKBIZ FGFR3 ADARB1 TNS1	1.48e-05	189	73	5	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPRZ1 CCNO MECOM FGFR3 SYBU	1.59e-05	192	73	5	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	PPP1R9A CCNO MECOM FGFR3 SYBU	1.63e-05	193	73	5	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	RLIM CCSER2 NFKBIZ XPC CAMSAP2	1.89e-05	199	73	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm\|5w / Sample Type, Dataset, Time_group, and Cell type.	POLA1 HPS1 IRF1 DGKH EP300	1.94e-05	200	73	5	0927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	SNAP91 PRICKLE2 ADARB1 CPEB1	5.67e-05	127	73	4	5e4d110cc6e68cd8fc7a4771a65e6f8cd83e7721
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCAN FGFR3 DCTN1 PLXNB1	9.48e-05	145	73	4	186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRZ1 SH3PXD2A FGFR3 RTN2	1.17e-04	153	73	4	82b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SH3PXD2A DNMT3A CDC42EP1	1.39e-04	160	73	4	0544bc465af208da448858d6e174ff56f2e08a46
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A4 ATP10B FGFR3 CDC42EP1	1.45e-04	162	73	4	3a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A4 ATP10B FGFR3 CDC42EP1	1.45e-04	162	73	4	04b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	KRBA1 FGFR3 PLXNB1 DNMT3A	1.71e-04	169	73	4	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHB DGKH NEURL1B EPHA3	1.71e-04	169	73	4	ccb7b2daa65cb5f4c1e7a48b3bcdf0cb8f7675c3
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JADE3 PRICKLE2 MECOM DGKH	1.75e-04	170	73	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNJ2 DACT3 DGKH NEURL1B	1.75e-04	170	73	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JADE3 PRICKLE2 MECOM DGKH	1.75e-04	170	73	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JADE3 PRICKLE2 MECOM DGKH	1.75e-04	170	73	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	JADE3 IRF1 NUB1 ARHGAP21	1.79e-04	171	73	4	341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	PTPRZ1 UNC13C DGKH FGFR3	1.79e-04	171	73	4	3965ced4be6db14265a90673502fceee425837ca
ToppCell	normal_Lung-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	PRUNE2 PRICKLE3 PPP1R9A SOCS6	1.79e-04	171	73	4	f49dfe11ae66d82125b577c48345a13683d7bb7b
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 ADARB1 TNS1 EPHA3	1.83e-04	172	73	4	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SLC9A4 PTPRZ1 CCNO FGFR3	1.87e-04	173	73	4	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PTPRZ1 CCNO ATP10B FGFR3	1.91e-04	174	73	4	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 NCAN FGFR3 PLXNB1	2.00e-04	176	73	4	ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPRZ1 PRICKLE2 MECOM PLXNB1	2.08e-04	178	73	4	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLA1 TONSL HASPIN CDC25A	2.13e-04	179	73	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRUNE2 PTPRZ1 UNC13C EPHA3	2.13e-04	179	73	4	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PTPRZ1 NCAN RTN2	2.17e-04	180	73	4	fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	NFKBIZ FGFR3 ADARB1 TNS1	2.17e-04	180	73	4	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PTPRZ1 NCAN RTN2	2.17e-04	180	73	4	907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCell	MS-Treg-naive_CD4\|MS / Condition, Cell_class and T cell subcluster	PRPF40B BRPF1 DGKH EIPR1	2.17e-04	180	73	4	7ca083616926d98420fa11a6e5ebc981623f79ac
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PTPRZ1 ATP10B FGFR3 MUC22	2.22e-04	181	73	4	faff2a34e391d053a17c926540e6cb46d94dd629
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PTPRZ1 ATP10B FGFR3 MUC22	2.22e-04	181	73	4	58651853f9c715075889856793df66ebe00c04f1
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PTPRZ1 ATP10B FGFR3 MUC22	2.22e-04	181	73	4	5a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNAP91 PRICKLE2 MECOM DGKH	2.22e-04	181	73	4	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PTPRZ1 ATP10B FGFR3 MUC22	2.22e-04	181	73	4	488a517f6e5543b648a2e72e0e04332fad776de6
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC9A4 PRPF40B SHB SMG9	2.32e-04	183	73	4	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.36e-04	184	73	4	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC9A4 POLA1 ADARB1 TNS1	2.41e-04	185	73	4	b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	PPP1R9A PRICKLE2 MECOM UNC13C	2.41e-04	185	73	4	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRBA1 MECOM NUB1 DMTN	2.41e-04	185	73	4	87151ab95530e70d61328b336518df58db584acb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRUNE2 PTPRZ1 UNC13C EPHA3	2.41e-04	185	73	4	a1b2525da018abe458908cab7268bd403ee98d92
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SLC9A4 NEURL1B ADARB1	2.41e-04	185	73	4	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.41e-04	185	73	4	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SLC9A4 ADARB1 TNS1	2.46e-04	186	73	4	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	IPF-Myeloid-DC_Mature\|World / Disease state, Lineage and Cell class	ERICH1 JADE3 SH3PXD2A NUB1	2.46e-04	186	73	4	d0d3953d9b199e0e792990b8551efb993393fe7e
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	SH3PXD2A DACT3 NEURL1B EPHA3	2.46e-04	186	73	4	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SLC9A4 ADARB1 TNS1	2.46e-04	186	73	4	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PPP1R9A NFKBIZ DGKH	2.46e-04	186	73	4	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRICKLE2 DGKH SYBU ARHGAP21	2.51e-04	187	73	4	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP10B FGFR3 PLXNB1 CDC42EP1	2.51e-04	187	73	4	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DGKH SYBU MUC12	2.51e-04	187	73	4	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	IPF-Myeloid-DC_Mature\|IPF / Disease state, Lineage and Cell class	ERICH1 JADE3 SH3PXD2A NUB1	2.51e-04	187	73	4	63e0304a0183b69aebb0d1a4640a506a0d6fb6e9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DGKH SYBU MUC12	2.51e-04	187	73	4	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DGKH SYBU MUC12	2.51e-04	187	73	4	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	DACT3 FGFR3 ADARB1 TNS1	2.57e-04	188	73	4	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SH3PXD2A NFKBIZ DNMT3A	2.57e-04	188	73	4	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DACT3 ADARB1 TNS1 EPHA3	2.57e-04	188	73	4	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	Mesenchymal_cells-Osteoblasts\|World / Lineage and Cell class	PTPRZ1 SH3PXD2A SYBU PLXNB1	2.57e-04	188	73	4	89f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLA1 PRICKLE2 SYBU CDC42EP1	2.62e-04	189	73	4	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.62e-04	189	73	4	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.62e-04	189	73	4	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PPP1R9A DGKH TNS1	2.62e-04	189	73	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.62e-04	189	73	4	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 SLC9A4 ADARB1 TNS1	2.67e-04	190	73	4	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	JADE3 CCNO MUC12 NEURL1B	2.67e-04	190	73	4	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DACT3 FGFR3 ADARB1 TNS1	2.67e-04	190	73	4	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	PTPRZ1 PPP1R9A CCNO MECOM	2.67e-04	190	73	4	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 ATP10B FGFR3 PLXNB1	2.67e-04	190	73	4	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLA1 HASPIN NEURL1B EPHA3	2.67e-04	190	73	4	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PRICKLE2 NFKBIZ DGKH	2.72e-04	191	73	4	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRICKLE2 CCNO MECOM FGFR3	2.72e-04	191	73	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DACT3 FGFR3 ADARB1 TNS1	2.72e-04	191	73	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SH3PXD2A NFKBIZ DNMT3A	2.72e-04	191	73	4	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 NCAN FGFR3 PLXNB1	2.78e-04	192	73	4	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ERICH1 JADE3 IRF1 NUB1	2.78e-04	192	73	4	e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPP1R9A MECOM DGKH NEURL1B	2.83e-04	193	73	4	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	SH3PXD2A PRICKLE2 IRF1 NFKBIZ	2.83e-04	193	73	4	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SHB CCNO MECOM	2.83e-04	193	73	4	371f4c98a599923fbe8382530b3eab05d873665a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A4 MECOM ATP10B PLXNB1	2.83e-04	193	73	4	536b277d90070c4571c592a3c6323b4bf4819f67
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRUNE2 SYNJ2 ARHGAP21 CPEB1	2.83e-04	193	73	4	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 NCAN FGFR3 PLXNB1	2.83e-04	193	73	4	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ERICH1 IRF1 NUB1 ARHGAP21	2.83e-04	193	73	4	d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A4 MECOM ATP10B PLXNB1	2.83e-04	193	73	4	0499611c21d283321ef6dd24add154dea48da1b7
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 NCAN FGFR3 PLXNB1	2.83e-04	193	73	4	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADARB1 TNS1 RTN2 EPHA3	2.89e-04	194	73	4	f15e81ff12525523c62d13105cf264ea72205e2e
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRZ1 MECOM ATP10B FGFR3	2.89e-04	194	73	4	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYNJ2 MECOM IRF1 NFKBIZ	2.89e-04	194	73	4	582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPRZ1 NCAN FGFR3 EPHA3	2.89e-04	194	73	4	68d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYNJ2 MECOM IRF1 NFKBIZ	2.89e-04	194	73	4	bda89111386398a072b70e8153b2a762298a047a
Computational	Genes in the cancer module 11.	SNAP91 PTPRZ1 PPP4R2 NCAN APC2 FGFR3 ADARB1 PLXNB1 DMTN	1.92e-04	540	42	9	MODULE_11
Drug	Carbarsone [121-59-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	SYNJ2 NFKBIB HPS1 CCSER2 CCNO FGFR3 SRRM2 PLXNB1	2.03e-07	197	72	8	3250_DN
Drug	Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	SYNJ2 MAX HPS1 SYBU SRRM2 DMTN DNMT3A	2.99e-06	197	72	7	3343_DN
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A	SYNJ2 FAM120C HPS1 IRF1 SOCS6 RTN2 PLXNB1	3.09e-06	198	72	7	4790_DN
Drug	Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A	PRICKLE3 FAM120C POLA1 HPS1 IRF1 RTN2 PLXNB1	3.30e-06	200	72	7	4783_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CCNO RPRD2 SRRM2 EP300 DNMT3A CDC42EP1	2.07e-05	177	72	6	6434_DN
Drug	prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A	FAM120C MAX HPS1 CCSER2 CCNO SRRM2	2.50e-05	183	72	6	6547_UP
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A	SYNJ2 MAX NFKBIB CDC25A RTN2 DNMT3A	3.00e-05	189	72	6	3371_DN
Drug	Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A	SYNJ2 MAX NFKBIB HPS1 RTN2 DMTN	3.09e-05	190	72	6	3172_DN
Drug	ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A	PRICKLE3 MAX NFKBIB HPS1 CCNO ADARB1	3.18e-05	191	72	6	5964_DN
Drug	Imipenem [74431-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A	NFKBIB HPS1 SOCS6 CDC25A PLXNB1 EPHA3	3.27e-05	192	72	6	2873_DN
Drug	Testosterone propionate [57-85-2]; Up 200; 11.6uM; PC3; HT_HG-U133A	SYNJ2 APC2 ATP10B ADARB1 EPHA3 DNMT3A	3.37e-05	193	72	6	4676_UP
Drug	Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A	PRICKLE3 NFKBIB HPS1 ADARB1 RTN2 CIC	3.47e-05	194	72	6	7352_UP
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A	SYNJ2 NFKBIB HPS1 ADARB1 EPHA3 DNMT3A	3.57e-05	195	72	6	3909_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; HL60; HT_HG-U133A	SYNJ2 FAM120C SH3PXD2A SHB CCSER2 CAMSAP2	3.57e-05	195	72	6	2705_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	SYNJ2 NFKBIB HPS1 CCSER2 ADARB1 TNS1	3.57e-05	195	72	6	2208_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	PRICKLE3 FAM120C CDC25A RTN2 DNMT3A CDC42EP1	3.57e-05	195	72	6	5573_DN
Drug	Fursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MAX SHB MECOM SYBU CDC25A PLXNB1	3.57e-05	195	72	6	4975_DN
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; HL60; HT_HG-U133A	PRICKLE3 SYNJ2 MAX HPS1 SOCS6 ADARB1	3.57e-05	195	72	6	2168_DN
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A	SYNJ2 BRPF1 NFKBIB CCNO ADARB1 PLXNB1	3.67e-05	196	72	6	3248_DN
Drug	Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A	HPS1 SMG9 CDC25A SRRM2 DMTN DNMT3A	3.67e-05	196	72	6	7470_DN
Drug	(-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A	MAX NFKBIB HPS1 SYBU DMTN DNMT3A	3.67e-05	196	72	6	3530_UP
Drug	Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A	HPS1 SHB CCNO IRF1 SOCS6 DCTN1	3.67e-05	196	72	6	3533_DN
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A	PRICKLE3 CCSER2 ADARB1 PLXNB1 DMTN DNMT3A	3.67e-05	196	72	6	3217_DN
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	SH3PXD2A SHB FGFR3 SYBU CIC DNMT3A	3.67e-05	196	72	6	5318_UP
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A	FAM120C NFKBIB ATP10B SRRM2 TNS1 DMTN	3.67e-05	196	72	6	3571_UP
Drug	Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SYNJ2 MAX NFKBIB HPS1 IRF1 SRRM2	3.67e-05	196	72	6	7187_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	PRICKLE3 SYNJ2 NFKBIB HPS1 ADARB1 PLXNB1	3.67e-05	196	72	6	2755_DN
Drug	0393-0188; Down 200; 10uM; MCF7; HT_HG-U133A	SYNJ2 MAX SOCS6 CDC25A DMTN CPEB1	3.67e-05	196	72	6	7531_DN
Drug	Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A	PRICKLE3 SYNJ2 UBR4 SHB FGFR3 TNS1	3.67e-05	196	72	6	2958_UP
Drug	Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A	POLA1 HPS1 IRF1 RPRD2 TNS1 CPEB1	3.78e-05	197	72	6	4547_DN
Drug	pentamidine isethionate salt; Down 200; 100uM; MCF7; HG-U133A	HPS1 MECOM CDC25A ADARB1 RTN2 PLXNB1	3.78e-05	197	72	6	639_DN
Drug	Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	SYNJ2 HPS1 CCNO SOCS6 PLXNB1 EPHA3	3.78e-05	197	72	6	3438_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	MAX UBR4 NFKBIB IRF1 ADARB1 RTN2	3.78e-05	197	72	6	1003_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A	PRUNE2 NFKBIB CDC25A ADARB1 PLXNB1 CDC42EP1	3.78e-05	197	72	6	1695_UP
Drug	Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A	PRUNE2 SYNJ2 SH3PXD2A NFKBIB FGFR3 EPHA3	3.89e-05	198	72	6	4265_UP
Drug	Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MAX NFKBIB SYBU CIC DMTN DNMT3A	3.89e-05	198	72	6	2898_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	SYNJ2 NFKBIB IRF1 CIC DNMT3A CDC42EP1	3.89e-05	198	72	6	5583_DN
Drug	Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A	SYNJ2 MAX HPS1 SYBU CDC25A CIC	3.89e-05	198	72	6	5284_UP
Drug	Iocetamic acid [16034-77-8]; Down 200; 6.6uM; HL60; HT_HG-U133A	PRUNE2 KSR1 SYNJ2 SH3PXD2A SOCS6 EPHA3	3.89e-05	198	72	6	3022_DN
Drug	Iobenguane sulfate; Up 200; 10.8uM; PC3; HT_HG-U133A	PRICKLE3 HPS1 CCSER2 IRF1 CPEB1 DNMT3A	3.89e-05	198	72	6	7299_UP
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; PC3; HT_HG-U133A	SYNJ2 CDC25A SRRM2 ADARB1 PLXNB1 CPEB1	3.89e-05	198	72	6	4592_DN
Drug	Caffeic acid [3331-39-5]; Up 200; 22.2uM; MCF7; HT_HG-U133A	FAM120C MAX HPS1 CDC25A CIC DNMT3A	3.89e-05	198	72	6	5352_UP
Drug	Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PRUNE2 SH3PXD2A PPP1R9A CCNO MECOM DMTN	4.00e-05	199	72	6	7163_UP
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A	SYNJ2 SYBU CDC25A TNS1 DMTN CDC42EP1	4.00e-05	199	72	6	4741_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A	KSR1 SYNJ2 SHB SOCS6 CAMSAP2 TNS1	4.11e-05	200	72	6	1164_UP
Drug	5-formyluracil	POLA1 CCNO XPC	6.63e-05	25	72	3	CID000304590
Drug	pifithrin-alpha	TONSL XPC EP300 DNMT3A	8.48e-05	73	72	4	CID000004817
Drug	BT325	SYNJ2 HPS1 CCNO	2.01e-04	36	72	3	CID000068933
Drug	TCPy	NFKBIZ DMTN	2.05e-04	7	72	2	CID000062764
Drug	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	PTPRZ1 DACT3 CCNO IRF1 NFKBIZ UNC13C ADARB1 RTN2 DNMT3A CDC42EP1	2.17e-04	807	72	10	ctd:C548651
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A_EA	MAX IRF1 SYBU RTN2 CDC42EP1	2.22e-04	173	72	5	995_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	PRICKLE3 CCNO RPRD2 SOCS6 EP300	2.22e-04	173	72	5	4458_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SMG9 RPRD2 SOCS6 SRRM2 CDC42EP1	2.28e-04	174	72	5	3993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	PRICKLE3 RPRD2 SOCS6 CDC25A CPEB1	2.34e-04	175	72	5	4072_DN
Drug	SAHA; Down 200; 10uM; PC3; HT_HG-U133A	SMG9 SOCS6 SRRM2 EP300 CPEB1	2.53e-04	178	72	5	4444_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SMG9 SOCS6 SRRM2 EP300 CDC42EP1	2.60e-04	179	72	5	6609_DN
Drug	Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	MAX NFKBIB CCNO RTN2 DNMT3A	2.66e-04	180	72	5	7420_UP
Drug	Cytosar-U	POLA1 TONSL HASPIN CCNO NUB1 FGFR3 DNMT3A	2.66e-04	399	72	7	CID000000596
Drug	thymine hydrate	POLA1 CCNO	2.73e-04	8	72	2	CID000151810
Drug	Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A	FAM120C HPS1 XPC FGFR3 SOCS6	2.73e-04	181	72	5	2857_UP
Drug	Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	NFKBIB CCSER2 IRF1 RTN2 DNMT3A	2.95e-04	184	72	5	5356_UP
Drug	valinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	NFKBIB IRF1 FGFR3 SRRM2 CDC42EP1	2.95e-04	184	72	5	5957_UP
Drug	5H-purin-2-amine	POLA1 NFKBIB TONSL ADARB1	3.09e-04	102	72	4	CID000409844
Drug	Rescinnamin [24815-24-5]; Up 200; 6.4uM; HL60; HT_HG-U133A	JADE3 MAX UBR4 SHB SRRM2	3.10e-04	186	72	5	2130_UP
Drug	Mometasone furoate [83919-23-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A	NFKBIB HPS1 CCNO FGFR3 EPHA3	3.17e-04	187	72	5	2896_DN
Drug	resveratrol; Down 200; 50uM; MCF7; HG-U133A	DCP2 HPS1 FGFR3 CDC25A SRRM2	3.42e-04	190	72	5	622_DN
Drug	Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A	NFKBIB FGFR3 SOCS6 EPHA3 DNMT3A	3.42e-04	190	72	5	3379_DN
Drug	Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	NFKBIB SOCS6 CDC25A CAMSAP2 ADARB1	3.42e-04	190	72	5	4114_DN
Drug	phosphorothioate	POLA1 DCP2 NFKBIB TONSL EP300 DMTN	3.49e-04	296	72	6	CID000167253
Drug	malathion diacid	NFKBIZ DMTN	3.50e-04	9	72	2	CID000014481
Drug	Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A	PPP1R9A IRF1 FGFR3 DMTN DNMT3A	3.58e-04	192	72	5	6044_DN
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A	FAM120C NFKBIB FGFR3 CDC25A DNMT3A	3.58e-04	192	72	5	3929_DN
Drug	rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A	SYNJ2 MAX UBR4 CCSER2 CAMSAP2	3.58e-04	192	72	5	1174_UP
Drug	Proguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SYNJ2 NFKBIB HPS1 IRF1 PLXNB1	3.58e-04	192	72	5	3505_DN
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; MCF7; HT_HG-U133A	PRICKLE3 NFKBIB HPS1 CCNO CDC25A	3.58e-04	192	72	5	6013_DN
Drug	Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; HL60; HT_HG-U133A	JADE3 UBR4 MECOM CAMSAP2 DMTN	3.67e-04	193	72	5	2131_UP
Drug	LY 294002; Down 200; 10uM; PC3; HT_HG-U133A	CDC25A SRRM2 TNS1 CPEB1 CDC42EP1	3.67e-04	193	72	5	4460_DN
Drug	5114445; Down 200; 10uM; MCF7; HT_HG-U133A_EA	MAX HPS1 CCNO FGFR3 SYBU	3.67e-04	193	72	5	901_DN
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ATP10B FGFR3 SOCS6 CDC25A SRRM2	3.67e-04	193	72	5	3943_DN
Drug	Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	MAX HPS1 CCSER2 SOCS6 EP300	3.67e-04	193	72	5	7008_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	SYNJ2 MAX FGFR3 SRRM2 CIC	3.67e-04	193	72	5	1667_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	SYNJ2 MAX HPS1 SHB FGFR3	3.67e-04	193	72	5	6985_DN
Drug	Retrorsine [480-54-6]; Down 200; 11.4uM; HL60; HT_HG-U133A	SYNJ2 MAX SHB CCSER2 TNS1	3.67e-04	193	72	5	2129_DN
Drug	Zidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A	PRICKLE3 FAM120C NFKBIB TNS1 CDC42EP1	3.67e-04	193	72	5	6733_DN
Drug	Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A	SYNJ2 MAX IRF1 CIC DMTN	3.76e-04	194	72	5	5448_DN
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A	MAX MECOM SOCS6 EP300 PLXNB1	3.76e-04	194	72	5	6272_DN
Drug	Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A	MAX NCAN NFKBIB CDC25A PLXNB1	3.76e-04	194	72	5	5525_UP
Drug	Benzethonium chloride [121-54-0]; Down 200; 9uM; MCF7; HT_HG-U133A	NFKBIB FGFR3 SOCS6 CIC DNMT3A	3.76e-04	194	72	5	6070_DN
Drug	paclitaxel; Down 200; 0.1uM; MCF7; HG-U133A	MAX BRPF1 FGFR3 TNS1 EP300	3.76e-04	194	72	5	640_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	SOCS6 CDC25A SRRM2 EP300 CPEB1	3.76e-04	194	72	5	1217_DN
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A	SYNJ2 NFKBIB CCNO CDC25A CAMSAP2	3.76e-04	194	72	5	3747_DN
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A	SYNJ2 NFKBIB SHB CDC25A CIC	3.76e-04	194	72	5	2864_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	BRPF1 HPS1 DCTN1 RTN2 CDC42EP1	3.76e-04	194	72	5	4804_DN
Drug	Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A	CCNO SYBU CDC25A ADARB1 DNMT3A	3.76e-04	194	72	5	6076_DN
Drug	Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A	MAX UBR4 NFKBIB CCSER2 TNS1	3.76e-04	194	72	5	2959_UP
Drug	17-DMAG; Up 200; 0.1uM; PC3; HT_HG-U133A	PRUNE2 NFKBIB HPS1 TNS1 CPEB1	3.76e-04	194	72	5	1213_UP
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	NKAPD1 CCSER2 SMG9 MECOM CDC25A	3.85e-04	195	72	5	6255_DN
Drug	Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MAX NFKBIB HPS1 SOCS6 CDC25A	3.85e-04	195	72	5	6233_DN
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A	BRPF1 NFKBIB CCNO PLXNB1 DNMT3A	3.85e-04	195	72	5	1522_DN
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A	MAX HPS1 SHB IRF1 EPHA3	3.85e-04	195	72	5	3504_DN
Disease	Malignant neoplasm of breast	PRICKLE3 SYNJ2 UBR4 APC2 MECOM GRIN2D TNS1 CIC EP300 PLXNB1 DNMT3A	5.58e-05	1074	72	11	C0006142
Disease	pulmonary function measurement, forced expiratory volume	MECOM DGKH TNS1	1.02e-04	37	72	3	EFO_0003892, EFO_0004314
Disease	smoking status measurement, Crohn's disease	MUC22 DNMT3A	1.22e-04	7	72	2	EFO_0000384, EFO_0006527
Disease	sialate O-acetylesterase measurement	HPS1 GOLGA5	3.81e-04	12	72	2	EFO_0803073
Disease	pulmonary function measurement, forced expiratory volume, smoking behaviour measurement	MECOM TNS1	3.81e-04	12	72	2	EFO_0003892, EFO_0004314, EFO_0005671
Disease	epilepsy (implicated_via_orthology)	PRICKLE3 PRICKLE2 UNC13C GRIN2D	6.89e-04	163	72	4	DOID:1826 (implicated_via_orthology)
Disease	Leukemia, Myelocytic, Acute	MECOM IRF1 EP300 DNMT3A	8.61e-04	173	72	4	C0023467
Disease	psoriatic arthritis	NFKBIZ MUC22 TNS1	1.27e-03	87	72	3	EFO_0003778
Disease	smoking status measurement, chronic obstructive pulmonary disease	MECOM IRF1 TNS1	1.32e-03	88	72	3	EFO_0000341, EFO_0006527
Disease	Lymphoma, T-Cell, Cutaneous	FGFR3 DNMT3A	1.44e-03	23	72	2	C0079773
Disease	Carcinoma of lung	IRF1 EPHA3	1.44e-03	23	72	2	C0684249
Disease	chronic obstructive pulmonary disease	SH3PXD2A SHB MECOM IRF1 FGFR3 TNS1 DNMT3A	1.44e-03	688	72	7	EFO_0000341
Disease	cortical thickness	SNAP91 SH3PXD2A MECOM FGFR3 SYBU TNS1 ARHGAP21 EPHA3 CPEB1	1.51e-03	1113	72	9	EFO_0004840
Disease	Adenocarcinoma of lung (disorder)	XPC FGFR3 EP300 EPHA3	1.64e-03	206	72	4	C0152013
Disease	Colorectal cancer	FGFR3 EP300	1.98e-03	27	72	2	cv:C0346629
Disease	COLORECTAL CANCER	FGFR3 EP300	1.98e-03	27	72	2	114500
Disease	Neoplasm of the large intestine	FGFR3 EP300	1.98e-03	27	72	2	cv:C0009404
Disease	chronic myeloid leukemia (is_marker_for)	FGFR3 DNMT3A	1.98e-03	27	72	2	DOID:8552 (is_marker_for)
Disease	hepatocellular carcinoma (biomarker_via_orthology)	PPP1R9A EP300 DNMT3A	2.37e-03	108	72	3	DOID:684 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSCGSPENASSGDDT	ERICH1	86	Q86X53
PALSASASDGTDFGS	EP300	21	Q09472
GSASAGELSSSEPST	DCTN1	171	Q14203
FESPSSGSDGAESPS	CCNO	61	P22674
SSGPGDTSSSAAERE	DNMT3A	6	Q9Y6K1
STSSSSSFDPSVFDG	SNAP91	706	O60641
SSDSDNGFSSTGSTP	DCP2	246	Q8IU60
SDTGSSAESSPFGSP	C2CD4C	216	Q8TF44
SFSSTAPSDTDLGES	ATP10B	636	O94823
GDSSPDTFSDGLSSS	IRF1	141	P10914
DTFSDGLSSSTLPDD	IRF1	146	P10914
STPSGSDLETTSGSD	MECOM	586	Q03112
SPSDSAGTSSASTDE	NUB1	551	Q9Y5A7
SPGSSSSFSGSEGED	KRBA1	641	A5PL33
GSPGSDSSDFSSASS	NFKBIZ	61	Q9BYH8
ISAFDGGSDSSSESE	MAX	131	P61244
TGFETTAASTTGSEP	MUC22	531	E2RYF6
EGSGFEGLDSSTASS	GOLGA5	451	Q8TBA6
EKSGPCSSSSDSDSG	NFKBIB	306	Q15653
PAFSTSTLLSGDGDS	PLXNB1	861	O43157
ESGSGPSTDTLSAAS	KSR1	191	Q8IVT5
LDGFSELDSESGSSS	KBTBD7	646	Q8WVZ9
TGAEDSSGSSPATSA	PTPRZ1	581	P23471
TSAAASAGPGEDSSD	DGKH	26	Q86XP1
GDDSFSSSGDLSLSA	ADARB1	196	P78563
GDDSLSDSGSFVSSR	POLA1	6	P09884
ESGSHESPDDSSSTA	EIPR1	106	Q53HC9
SAGEDPNGSDSSDSA	PRICKLE2	311	Q7Z3G6
SSSSESSEDDGFFLG	PRICKLE3	551	O43900
GSSFELSPSDSSDGT	CCSER2	496	Q9H7U1
TSSDDSFSLSSGDPG	APC2	866	O95996
YSSGSPEGGSDSSES	HECTD1	706	Q9ULT8
SASEGESPAFSSASS	DACT3	551	Q96B18
ESPAFSSASSDSDGS	DACT3	556	Q96B18
DSSHSSSSDGDEPNG	FAM120C	521	Q9NX05
GKLSFDSSPTSSTDG	CDC42EP1	136	Q00587
FETSPDSFSISGESS	EPHA3	526	P29320
SSEPSSSDAASGDAT	ATF7IP	161	Q6VMQ6
SSDAASGDATSGDAP	ATF7IP	166	Q6VMQ6
SSGSSDASIGDPSQS	HASPIN	46	Q8TF76
SSPSDSDTSGFSSGS	CPEB1	181	Q9BZB8
DTPSSSSSGDDSVFA	FGFR3	776	P22607
PTGGSSAETETDSFS	HPS1	281	Q92902
LQSTEFSPSGSETGS	DMTN	301	Q08495
SSFDNGPSSASELAS	RPRD2	1136	Q5VT52
VLDSSSDFPSSGEGA	CAMSAP2	371	Q08AD1
DSSDESPSTSFTSGS	JADE3	11	Q92613
LGGFSEPDSESGSSS	KBTBD6	646	Q86V97
SEGSENEGPVSSSSS	PPP4R2	361	Q9NY27
SSESTDSGFCLDSPG	CDC25A	76	P30304
STASSTPDSTEGGND	RTN2	16	O75298
SCFSASSGSLPDDSG	SHB	61	Q15464
SSGSLPDDSGSTSDL	SHB	66	Q15464
SGSSSSDSEGSSLPV	SRRM2	2556	Q9UQ35
NDSVDGDSFSSLSSP	PRUNE2	1626	Q8WUY3
GDFLSTSSATSPDSD	SYNJ2	1381	O15056
SESGVFDTAESPTSG	NCAN	756	O14594
DDSSDPGSPSITFSA	SLC9A4	681	Q6AI14
SPSHESSSSSGSDEG	SMG9	346	Q9H0W8
SRGTFPEDSSEDTSG	BRPF1	1031	P55201
SSESSSGRAAGDTPE	CIC	1306	Q96RK0
ADSSSEFSEETGASG	NKAPD1	181	Q6ZUT1
SSSSLAPSEGSSDGE	UNC13C	156	Q8NB66
KPGSEADFSSSSSTG	SYBU	141	Q9NX95
DTLSARGSSGDSDSP	SH3PXD2A	631	Q5TCZ1
GPASSSSSSEGEDSA	TONSL	736	Q96HA7
SGGESSETSSDLFEG	RLIM	481	Q9NVW2
DSTSVGSFPSGESSD	TNS1	1086	Q9HBL0
TTTPSGSLSGSQDDS	NEURL1B	441	A8MQ27
SGSEPSSSLDSVESG	PRPF40B	741	Q6NWY9
SGSDFELSSGEASDP	XPC	441	Q01831
SNGTGDSDSAAPTTT	UBR4	2456	Q5T4S7
GVSPGDVSDSATSDS	ARHGAP21	1376	Q5T5U3
AGTPSGSSADEDTFS	SOCS6	91	O14544
GSSADEDTFSSSSAP	SOCS6	96	O14544
STTSGLTEESTAFPG	MUC12	2431	Q9UKN1
ADLGEESTTFPSSSG	MUC12	2461	Q9UKN1
TTSGLTEESTAFPGS	MUC12	2906	Q9UKN1
DLGEESTTFPSSSGS	MUC12	2936	Q9UKN1
DFSPSSTSSADLSGL	PPP1R9A	926	Q9ULJ8
SPSDSEDSESLGGAS	GRIN2D	1111	O15399