Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 OR51F1 GNRHR2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

6.83e-0988416927GO:0004930
GeneOntologyMolecularFunctionsomatostatin receptor activity

SSTR1 SSTR2 SSTR3 SSTR5

2.46e-0851694GO:0004994
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

EPHB4 UTS2R GPR65 OR9K2 GPER1 OPN3 ROR1 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 OR51F1 GNRHR2 PTK2B EDAR PROKR2 ACKR3 ABCC8 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

1.02e-07135316932GO:0004888
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

UTS2R FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 PROKR2

1.78e-051331698GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

UTS2R FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 PROKR2

2.58e-051401698GO:0001653
GeneOntologyMolecularFunctionneuropeptide receptor activity

SSTR1 SSTR2 SSTR3 SSTR5 PROKR2

8.46e-05531695GO:0008188
GeneOntologyMolecularFunctiondynein light intermediate chain binding

BICD2 DNHD1 DNAH12 DYNC1H1

8.65e-05281694GO:0051959
GeneOntologyMolecularFunctionneuropeptide binding

SSTR1 SSTR2 SSTR3 SSTR5

2.63e-04371694GO:0042923
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH12 DYNC1H1

4.43e-04181693GO:0008569
GeneOntologyBiologicalProcesssomatostatin receptor signaling pathway

SSTR1 SSTR2 SSTR3 SSTR5

6.14e-0861674GO:0038169
GeneOntologyBiologicalProcesssomatostatin signaling pathway

SSTR1 SSTR2 SSTR3 SSTR5

6.14e-0861674GO:0038170
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 OR51F1 GNRHR2 PTK2B CDK5R1 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 PLCE1 OR4F6

7.92e-07139516730GO:0007186
GeneOntologyBiologicalProcessresponse to starvation

MYH13 ITFG2 GAS6 CPS1 SSTR1 SSTR2 SSTR3 MAP3K5 RRAGA FNIP1

1.81e-0522916710GO:0042594
Domain7tm_1

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 GNRHR2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

2.00e-1067716326PF00001
DomainG_PROTEIN_RECEP_F1_1

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 GNRHR2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

2.57e-1068516326PS00237
DomainG_PROTEIN_RECEP_F1_2

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 GNRHR2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

3.10e-1069116326PS50262
DomainGPCR_Rhodpsn

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 GNRHR2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

3.20e-1069216326IPR000276
DomainGPCR_Rhodpsn_7TM

UTS2R GPR65 OR9K2 GPER1 OPN3 FPR3 OR2W5P GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 OR14A16 BDKRB2 PROKR2 ACKR3 OR6C76 OR6C75 OR4K1 OR52N4 CCR6 OR4F21 OR51G1 OR4F6

8.41e-1067016325IPR017452
DomainSomatstn_rcpt

SSTR1 SSTR2 SSTR3 SSTR5

2.78e-0851634IPR000586
DomainClathrin/coatomer_adapt-like_N

AP2A1 AP2A2 NCAPD2 AP3D1

7.08e-06151634IPR002553
DomainAdaptin_N

AP2A1 AP2A2 NCAPD2 AP3D1

7.08e-06151634PF01602
DomainARM-type_fold

ZYG11A DNAJC13 DOCK8 BTAF1 NCDN AP2A1 AP2A2 XPO5 NOM1 EIF4G1 NCAPD2 PKP1 AP3D1

9.02e-0633916313IPR016024
Domain-

AP2A1 AP2A2

7.57e-05216322.60.40.1030
DomainClathrin_a-adaptin_app_Ig-like

AP2A1 AP2A2

7.57e-0521632IPR013038
DomainAP2_complex_asu

AP2A1 AP2A2

7.57e-0521632IPR017104
DomainClathrin_a-adaptin_app_sub_C

AP2A1 AP2A2

7.57e-0521632IPR003164
DomainAlpha_adaptin_C

AP2A1 AP2A2

7.57e-0521632PF02296
DomainARM-like

ZYG11A DNAJC13 DOCK8 BTAF1 AP2A1 AP2A2 XPO5 NCAPD2 PKP1 AP3D1

1.34e-0427016310IPR011989
Domain-

ZYG11A DNAJC13 BTAF1 AP2A1 AP2A2 XPO5 NCAPD2 PKP1 AP3D1

1.48e-0422216391.25.10.10
DomainDynein_heavy_dom-2

DNHD1 DNAH12 DYNC1H1

2.21e-04141633IPR013602
DomainDHC_N2

DNHD1 DNAH12 DYNC1H1

2.21e-04141633PF08393
DomainDHC_fam

DNHD1 DNAH12 DYNC1H1

2.75e-04151633IPR026983
DomainDynein_heavy

DNHD1 DNAH12 DYNC1H1

2.75e-04151633PF03028
DomainDynein_heavy_dom

DNHD1 DNAH12 DYNC1H1

2.75e-04151633IPR004273
DomainClathrin_a/coatomer_app_sub_C

AP2A1 AP2A2

4.49e-0441632IPR015873
Domain-

AP2A1 AP2A2

4.49e-04416323.30.310.30
DomainMA3

NOM1 EIF4G1

1.11e-0361632SM00544
DomainMA3

NOM1 EIF4G1

1.11e-0361632PF02847
DomainInitiation_fac_eIF4g_MI

NOM1 EIF4G1

1.11e-0361632IPR003891
DomainMI

NOM1 EIF4G1

1.11e-0361632PS51366
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR65 GPER1 OPN3 FPR3 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 ACKR3 CCR6

5.95e-0818612012MM15994
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

UTS2R GPR65 GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 ACKR3 CCR6

1.30e-0733012015M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

UTS2R GPR65 GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 ACKR3 CCR6

1.46e-0733312015MM14963
PathwayWP_GPCRS_NONODORANT

UTS2R GPR65 GPER1 OPN3 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 ACKR3 CCR6

4.17e-0726612013MM15843
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

UTS2R GPER1 FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 PROKR2 ACKR3 CCR6

9.25e-0719712011M12289
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

UTS2R GPER1 FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 PROKR2 ACKR3 CCR6

9.25e-0719712011MM14970
PathwayWP_GPCRS_PEPTIDE

FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 CCR6

2.09e-06701207MM15959
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR65 GPER1 OPN3 FPR3 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 ACKR3 CCR6

2.17e-0626012012M39397
PathwayWP_PEPTIDE_GPCRS

FPR3 SSTR1 SSTR2 SSTR3 SSTR5 BDKRB2 CCR6

3.34e-06751207M39696
PathwayREACTOME_GPCR_LIGAND_BINDING

UTS2R GPR65 GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 ACKR3 CCR6

3.65e-0643012015MM15160
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 ACKR3 CCR6

6.44e-0628912012MM15057
PathwayREACTOME_GPCR_LIGAND_BINDING

UTS2R GPR65 GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 ACKR3 CCR6

8.91e-0646312015M507
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

GPER1 OPN3 FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 ACKR3 CCR6

1.49e-0531412012M600
PathwayREACTOME_SIGNALING_BY_GPCR

UTS2R GPR65 GPER1 OPN3 FPR3 OBSCN GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 PDE8B ACKR3 CCR6

3.24e-0564612017MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

UTS2R GPR65 GPER1 OPN3 FPR3 OBSCN GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 PROKR2 PDE8B ACKR3 CCR6

9.09e-0570212017M746
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

ROR1 AP2A1 AP2A2

1.25e-04121203MM15163
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

ROR1 AP2A1 AP2A2

1.62e-04131203M27415
PathwayWP_8Q1123_RB1CC1_COPY_NUMBER_VARIATION

ATG13 MAP3K5 PTK2B

3.11e-04161203M48107
PathwayWP_HDAC6_INTERACTIONS_IN_THE_CENTRAL_NERVOUS_SYSTEM

ATP13A2 BDNF MAP3K5 CNOT6 PTK2B SMAD2

4.04e-041131206M48336
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

GPER1 OPN3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 BDKRB2 GNRHR2 ACKR3 CCR6

4.54e-102001741218240029
Pubmed

Somatostatin sst2 receptor knock-out mice: localisation of sst1-5 receptor mRNA and binding in mouse brain by semi-quantitative RT-PCR, in situ hybridisation histochemistry and receptor autoradiography.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174411897118
Pubmed

[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy].

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174411753241
Pubmed

Acromegaly: correlation between expression of somatostatin receptor subtypes and response to octreotide-lar treatment.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174419330452
Pubmed

Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174412414882
Pubmed

Profiling of somatostatin receptor subtype expression by quantitative PCR and correlation with clinicopathological features in pancreatic endocrine tumors.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174420717067
Pubmed

Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174412021920
Pubmed

Immunohistochemical detection and localization of somatostatin receptor subtypes in prostate tissue from patients with bladder outlet obstruction.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174418936524
Pubmed

Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-09517448449518
Pubmed

An immunohistochemical investigation of the expression of somatostatin receptor subtypes - should therapeutic trials be performed to determine the efficacy of somatostatin analogs in treating advanced thyroid malignances?

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174425962406
Pubmed

Prognostic Value of Somatostatin Receptor Subtypes in Pancreatic Neuroendocrine Tumors.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174426474434
Pubmed

Somatostatin receptor subtypes in human type 2 diabetic islets.

SSTR1 SSTR2 SSTR3 SSTR5

3.01e-095174420182388
Pubmed

Identification and characterization of a novel human cortistatin-like peptide.

SSTR1 SSTR2 SSTR3 SSTR5

9.01e-09617449125122
Pubmed

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

SSTR1 SSTR2 SSTR3 SSTR5

9.01e-09617441346068
Pubmed

Brain somatostatin receptors are up-regulated in somatostatin-deficient mice.

SSTR1 SSTR2 SSTR3 SSTR5

9.01e-096174412145348
Pubmed

Genetic variation in the SST gene and its receptors in relation to circulating levels of insulin-like growth factor-I, IGFBP3, and prostate cancer risk.

SSTR1 SSTR2 SSTR3 SSTR5

9.01e-096174419423539
Pubmed

Immunohistochemical distribution of somatostatin and somatostatin receptor subtypes (SSTR1-5) in hypothalamus of ApoD knockout mice brain.

SSTR1 SSTR2 SSTR3 SSTR5

2.09e-087174422581439
Pubmed

Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, SSTR1 and SSTR1/SSTR2 knockout mouse cochlea.

SSTR1 SSTR2 SSTR3 SSTR5

2.09e-087174425149275
Pubmed

Null mutant mouse models of somatostatin and cortistatin, and their receptors.

SSTR1 SSTR2 SSTR3 SSTR5

2.09e-087174418206294
Pubmed

Dissociation of heterotrimeric g proteins in cells.

FPR3 GPR55 SSTR1 SSTR2 SSTR3 SSTR5 CHRM4 GNRHR2 ACKR3 CCR6

2.64e-081791741018577758
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 PALD1 NUP85 ESYT1 OBSCN LAMA5 BTAF1 MED13L ATP13A2 CHRM4 RYR1 MAP3K5 GRAMD2A CDK5R1 INTS5 PNPLA6 AP2A1 SBF2 EIF4G1 NCAPD2 AP3D1 DYNC1H1

4.02e-0811051742235748872
Pubmed

Gene expression of somatostatin receptor subtypes SSTR2a, SSTR3 and SSTR5 in peripheral blood of neuroendocrine lung cancer affected patients.

SSTR2 SSTR3 SSTR5

1.23e-073174321503779
Pubmed

Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines.

SSTR1 SSTR2 SSTR3

1.23e-073174312474541
Pubmed

Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive receptor activation.

SSTR2 SSTR3 SSTR5

1.23e-073174317609435
Pubmed

Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis.

SSTR1 SSTR2 SSTR5

1.23e-07317439892225
Pubmed

Expression Analysis of SSTR 1, 2 and 3 in Small-cell Lung Cancer Patients as Targets for Future Peptide Receptor Radionuclide Therapy.

SSTR1 SSTR2 SSTR3

1.23e-073174339197921
Pubmed

Overexpression and functional relevance of somatostatin receptor-1, -2, and -5 in endometrium and endometriotic lesions.

SSTR1 SSTR2 SSTR5

1.23e-073174320739383
Pubmed

Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study.

SSTR1 SSTR2 SSTR3 SSTR5

1.24e-0710174416214911
Pubmed

Differential expression of somatostatin and dopamine receptor subtype genes in adrenocorticotropin (ACTH)-secreting pituitary tumors and silent corticotroph adenomas.

SSTR1 SSTR2 SSTR5

4.91e-074174319318729
Pubmed

Somatostatin and dopamine receptor expression in neuroendocrine neoplasms: correlation of immunohistochemical findings with somatostatin receptor scintigraphy visual scores.

SSTR2 SSTR3 SSTR5

4.91e-074174325808161
Pubmed

Predictive and prognostic significance of tumour subtype, SSTR1-5 and e-cadherin expression in a well-defined cohort of patients with acromegaly.

SSTR1 SSTR2 SSTR5

4.91e-074174333491286
Pubmed

Molecular cloning and expression of a type-two somatostatin receptor in goldfish brain and pituitary.

SSTR1 SSTR2 SSTR3

4.91e-074174310996426
Pubmed

Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt.

SSTR1 SSTR2 SSTR3

1.22e-065174311344221
Pubmed

Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours.

SSTR1 SSTR2 SSTR5

1.22e-06517439279525
Pubmed

Characterisation of [125I]-Tyr0DTrp8-somatostatin binding in sst1- to sst4- and SRIF-gene-invalidated mouse brain.

SSTR1 SSTR2 SSTR3

1.22e-065174312759718
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

EPHB4 PTPMT1 NUP85 ESYT1 GCDH BTAF1 NCDN LARP4B INTS5 PNPLA6 AP2A1 XPO5 SEC24B EIF4G1 NCAPD2 OGA MTCH2 DYNC1H1

1.34e-069421741831073040
Pubmed

Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.

SSTR1 SSTR2 SSTR3 SSTR5

1.75e-0618174420810604
Pubmed

Defining the membrane proteome of NK cells.

DNAJC13 CARMIL2 NUP85 DOCK8 ESYT1 ANO10 NCDN CNOT6 LARP4B INTS5 PNPLA6 AP2A1 TUBGCP3 EIF4G1 NCAPD2 OGA MAP2K3 MTCH2 AP3D1 DYNC1H1

1.81e-0611681742019946888
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

SSTR3 SSTR5 CHRM4 BDKRB2 ACKR3 CCR6

2.18e-067517462834384
Pubmed

Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin.

SSTR1 SSTR3 SSTR5

2.43e-06617439205124
Pubmed

Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes.

AP2A1 AP2A2 AP3D1

2.43e-066174322650988
Pubmed

Expression of Ki-67, PTTG1, FGFR4, and SSTR 2, 3, and 5 in nonfunctioning pituitary adenomas: a high throughput TMA, immunohistochemical study.

SSTR2 SSTR3 SSTR5

2.43e-066174322419713
Pubmed

Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation.

MAP3K5 AP2A1 MAP2K3

4.24e-067174316709866
Pubmed

Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.

SSTR1 SSTR2 SSTR3 SSTR5

8.30e-062617449226367
Pubmed

Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system.

AP2A1 AP2A2 AP3D1

1.01e-059174311591131
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DNAJC13 ATG13 GAS6 OBSCN BTAF1 WDR25 NCDN LRCH3 PTPDC1 PNPLA6 ACKR3 ABCC8 SBF2 VPS35L SPACA6 FNIP1 DHRSX MME MAP2K3 AFF4 DOP1A

1.92e-0514891742128611215
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ZNF618 MYO19 ROR1 OBSCN MAGEE2 RYR1 IVNS1ABP FBXL7 EDAR AGL KCNS2 NCR1 SNRNP200 DYNC1H1

2.22e-057361741429676528
Pubmed

Cytoplasmic expression of SSTR2 and 5 by immunohistochemistry and by RT/PCR is not associated with the pharmacological response to octreotide.

SSTR2 SSTR5

2.49e-052174225008035
Pubmed

Somatostatin receptor 1 and 5 double knockout mice mimic neurochemical changes of Huntington's disease transgenic mice.

SSTR1 SSTR5

2.49e-052174221912697
Pubmed

Octreotide in combination with AT-101 induces cytotoxicity and apoptosis through up-regulation of somatostatin receptors 2 and 5 in DU-145 prostate cancer cells.

SSTR2 SSTR5

2.49e-052174226531719
Pubmed

Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: the relationship with endogenous srif activity and response to octreotide.

SSTR2 SSTR5

2.49e-052174215118275
Pubmed

Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes.

SSTR1 SSTR3

2.49e-052174212376335
Pubmed

Expression of somatostatin receptor subtype 2 and subtype 5 in thyroid malignancies.

SSTR2 SSTR5

2.49e-052174224967740
Pubmed

Analysis of somatostatin receptors 2 and 5 polymorphisms in patients with acromegaly.

SSTR2 SSTR5

2.49e-052174215914528
Pubmed

Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma.

ROR1 MAP3K5

2.49e-052174226661061
Pubmed

Somatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: an in vivo and in vitro study.

SSTR2 SSTR5

2.49e-052174214602773
Pubmed

Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

SSTR2 SSTR5

2.49e-052174217272399
Pubmed

Altered morphology of rod bipolar cell axonal terminals in the retinas of mice carrying genetic deletion of somatostatin subtype receptor 1 or 2.

SSTR1 SSTR2

2.49e-052174214750962
Pubmed

Expression of somatostatin receptors, SSTR2A and SSTR5, in 108 endocrine pituitary tumors using immunohistochemical detection with new specific monoclonal antibodies.

SSTR2 SSTR5

2.49e-052174224182563
Pubmed

Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).

AP2A1 AP2A2

2.49e-05217422564002
Pubmed

Docetaxel in combination with octreotide shows synergistic apoptotic effect by increasing SSTR2 and SSTR5 expression levels in prostate and breast cancer cell lines.

SSTR2 SSTR5

2.49e-052174225925002
Pubmed

Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas.

SSTR1 SSTR2

2.49e-052174218624922
Pubmed

Increased SSTR2A and SSTR3 expression in succinate dehydrogenase-deficient pheochromocytomas and paragangliomas.

SSTR2 SSTR3

2.49e-052174225554089
Pubmed

Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers.

SSTR1 SSTR5

2.49e-052174210713101
Pubmed

Characterization of somatostatin receptor 2 and 5 expression in operable hepatocellular carcinomas.

SSTR2 SSTR5

2.49e-052174222640914
Pubmed

SSTR1 and SSTR5 subtypes are the dominant forms of somatostatin receptor in neuroendocrine tumors.

SSTR1 SSTR5

2.49e-052174220529830
Pubmed

Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices.

SSTR1 SSTR2

2.49e-052174215548214
Pubmed

Effects of somatostatin analogues on retinal angiogenesis in a mouse model of oxygen-induced retinopathy: involvement of the somatostatin receptor subtype 2.

SSTR1 SSTR2

2.49e-052174219324858
Pubmed

Expression of somatostatin receptors 1 and 2 in the adult mouse kidney.

SSTR1 SSTR2

2.49e-052174215093692
Pubmed

Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

HIC1 ACKR3

2.49e-052174219525223
Pubmed

Antiangiogenic role of somatostatin receptor 2 in a model of hypoxia-induced neovascularization in the retina: results from transgenic mice.

SSTR1 SSTR2

2.49e-052174217652715
Pubmed

Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear.

SSTR1 SSTR2

2.49e-052174225268135
Pubmed

Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study.

SSTR1 SSTR2

2.49e-052174211527930
Pubmed

Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines.

SSTR3 SSTR5

2.49e-05217429177396
Pubmed

Modulation of expression of somatostatin receptor subtypes in Graves' ophthalmopathy orbits: relevance to novel analogs.

SSTR1 SSTR2

2.49e-052174217848636
Pubmed

Gene expression of somatostatin receptor subtypes, SSTR1 and SSTR2, in human lung cancer cell lines.

SSTR1 SSTR2

2.49e-05217427968260
Pubmed

Distinct patterns of expression and physiological effects of sst1 and sst2 receptor subtypes in mouse hypothalamic neurons and astrocytes in culture.

SSTR1 SSTR2

2.49e-05217429166719
Pubmed

Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis.

SSTR2 SSTR3

2.49e-052174222651821
Pubmed

Functional correlates of somatostatin receptor 2 overexpression in the retina of mice with genetic deletion of somatostatin receptor 1.

SSTR1 SSTR2

2.49e-052174215464758
Pubmed

6agonist selectivity determinants in somatostatin receptor subtypes I and II.

SSTR1 SSTR2

2.49e-05217427929134
Pubmed

Octreotide promotes apoptosis in human somatotroph tumor cells by activating somatostatin receptor type 2.

SSTR2 SSTR5

2.49e-052174216954443
Pubmed

Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization.

SSTR2 SSTR5

2.49e-052174218653781
Pubmed

Protective role of somatostatin receptor 2 against retinal degeneration in response to hypoxia.

SSTR1 SSTR2

2.49e-052174222311350
Pubmed

Somatostatin receptor type 5 modulates somatostatin receptor type 2 regulation of adrenocorticotropin secretion.

SSTR2 SSTR5

2.49e-052174215857828
Pubmed

Somatostatin receptor 1 (SSTR1) and somatostatin receptor 5 (SSTR5)expression in hepatocellular carcinoma.

SSTR1 SSTR5

2.49e-052174224634938
Pubmed

Sulfonylurea receptor knockout causes glucose intolerance in mice that is not alleviated by concomitant somatostatin subtype receptor 5 knockout.

SSTR5 ABCC8

2.49e-052174212035032
Pubmed

Somatostatin Receptors 2A and 5 Are Expressed in Merkel Cell Carcinoma with No Association with Disease Severity.

SSTR2 SSTR5

2.49e-052174225765179
Pubmed

Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.

AP2A1 AP2A2

2.49e-052174212036598
Pubmed

Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner.

SSTR2 SSTR5

2.49e-052174233434183
Pubmed

A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD.

GPER1 GAS6

2.49e-052174231300420
Pubmed

SPAG4L/SPAG4Lβ interacts with Nesprin2 to participate in the meiosis of spermatogenesis.

SPAG4 SYNE2

2.49e-052174231144711
Pubmed

Changes in neuronal response to ischemia in retinas with genetic alterations of somatostatin receptor expression.

SSTR1 SSTR2

2.49e-052174217425570
Pubmed

Somatostatin receptors SSTR2 and SSTR5 are expressed in the human thoracic duct.

SSTR2 SSTR5

2.49e-052174221667819
Pubmed

The role of G-proteins in the dimerisation of human somatostatin receptor types 2 and 5.

SSTR2 SSTR5

2.49e-052174219748526
Pubmed

Somatostatin receptors type 2 and 5 expression and localization during human pituitary development.

SSTR2 SSTR5

2.49e-052174224189142
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

NUP85 ESYT1 NCDN AP2A1 AP2A2 XPO5 NT5DC2 TUBGCP3 EIF4G1 NCAPD2 SNRNP200 DYNC1H1

2.78e-055601741235241646
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BICD2 PALD1 ATG13 MED13L NCDN XPO5 FNIP1 PPIP5K1 DYNC1H1 PLCE1

4.24e-054071741012693553
Pubmed

APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.

AP2A1 AP2A2 AP3D1

4.30e-0514174329262337
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

DNAJC13 ESYT1 LAMA5 DALRD3 LRCH3 INTS5 DNAH12 AP2A2 FNIP1 DHX29 AFF4

4.44e-054961741131343991
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

OBSCN SOCS6 RYR1 MAP3K5 IVNS1ABP LARP4B AGL SYNE2 TUBGCP3 SMAD2 PLCE1

4.52e-054971741123414517
InteractionSST interactions

SSTR1 SSTR2 SSTR3 SSTR5

4.91e-0791624int:SST
Cytoband12q13.2

OR9K2 ESYT1 OR6C76 OR6C75

5.98e-0555175412q13.2
GeneFamilySomatostatin receptors

SSTR1 SSTR2 SSTR3 SSTR5

8.88e-0951194257
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPIPB4 ZDBF2 BTAF1 ANKRD36C AQP1 ZAP70 SYNE2 SNRNP200

1.07e-06197173857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB4 OBSCN AQP1 PTK2B MFAP5 EDAR ACKR3

4.67e-061701737af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZYG11A SPACA9 DNAH12 SPAG17 CCDC180 CFAP46 IGSF23

4.85e-06171173752aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB4 OBSCN AQP1 PTK2B MFAP5 EDAR ACKR3

5.04e-0617217379a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIC1 GPR65 DUSP2 GPR55 ZAP70 PROKR2 NCR1

7.30e-0618217379d727ab84da8de33f1021b492c90d8b4c2a8ea23
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SSTR2 SSTR3 MBOAT4 CHRM4 TMEM196 PDE8B ABCC8

7.57e-0618317378820cfed27b292bc0bc9cde4005219ed41900552
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ROR1 GAS6 LAMA5 ITLN2 BDNF GRAMD2A PLCE1

7.57e-0618317376821dca076318115d360ff426eb1218cfe104063
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SSTR2 SSTR3 MBOAT4 TMEM196 XKR7 PDE8B ABCC8

9.67e-061901737b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B PLCE1

1.00e-0519117373457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPIPB4 BTAF1 ANKRD36C AQP1 ZAP70 LRCH3 SYNE2

1.07e-0519317379337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

EPHB4 PALD1 ZNF618 FPR3 GAS6 CYTL1 CCR6

1.11e-0519417377ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCellControl-Myeloid-MoAM4|Control / Condition, Lineage and Cell class

EPHB4 PALD1 ZNF618 FPR3 GAS6 CYTL1 CCR6

1.14e-051951737211a736acbe875bd3c1942c62aaacc9b170ece6d
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B PLCE1

1.22e-0519717379ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GPR65 DUSP2 ANKRD36C ZAP70 TBC1D31 SYNE2 NCR1

1.26e-05198173758d805e827299292750b09c6283fdbe406b75f79
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B PLCE1

1.26e-0519817370047a9ef7684230ac5179efea94461480e90bdaf
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CARMIL2 DOCK8 ZAP70 DPEP2 SEC24B CCR6 NCR1

1.31e-0519917375611b9e405a685a7a099d2f2d21dee3a939c2911
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Striatum / BrainAtlas - Mouse McCarroll V32

UTS2R MYH13 CPS1 SSTR5 FRMPD3

2.03e-05851735a7a5d82924cd4a41ab87b1abf13143635882a4b2
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

UTS2R MYH13 CPS1 SSTR5 FRMPD3

2.03e-0585173586c5d71b66ff55c44d2d457865dda72e07e5ec53
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

UTS2R MYH13 CPS1 SSTR5 FRMPD3

2.03e-0585173567336aa7ec02b64595ce7d5222d43cead92eb52e
ToppCelldroplet-Liver-Npc-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 SSTR1 MEP1A FCGBP EDAR PKP1

3.22e-051551736d883a3869cf893d62741f26f641ed3923aba03f9
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PALD1 GAS6 MPEG1 ATP13A2 NIBAN3 ALDH7A1

3.85e-05160173661f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PALD1 GAS6 MPEG1 ATP13A2 NIBAN3 ALDH7A1

3.85e-05160173634b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

5.05e-051681736fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MPEG1 GPR55 SPACA9 XPO5 DPEP2 NCAPD2

5.05e-05168173652fd65024af8683db11d931f7563cbe8eb815d1c
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCDH AQP1 MEP1A CHPT1 ACKR3 MME

5.05e-051681736b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

5.05e-0516817367edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B

5.22e-051691736815474855a70498a74e52f6583113c63b7267a0c
ToppCellmild_COVID-19_(asymptomatic)-RBC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ESYT1 ZDBF2 SSTR2 NCDN INTS5 NCAPD2

5.58e-05171173678491478ba65bad45238fe114f5251b2adea323d
ToppCellfacs-Heart-RV-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP2 GPR55 WDR25 PTK2B CCR6 ZPBP2

5.76e-051721736d061ea21bee179df5a525842e9a48621a8e1461b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPN3 ROR1 ZDBF2 TENT5B NCAPD2 KNL1

5.95e-0517317366c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

GCDH FCGBP NT5DC2 NCAPD2 PPIP5K1 KNL1

6.34e-051751736bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

6.54e-051761736b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN IVNS1ABP CHPT1 ABCC8 FRMPD3 CFAP46

6.75e-051771736692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCDH AQP1 MEP1A CHPT1 SLC25A10 ALDH7A1

6.75e-0517717367f58286fc8797e9bdcf8ece0849f55680905955d
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN IVNS1ABP CHPT1 ABCC8 FRMPD3 CFAP46

6.75e-051771736c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DUSP2 RYR1 SLC25A10 FASTKD3 KNL1 PLCE1

7.18e-0517917369dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITFG2 ROR1 ZRANB3 BDNF ITIH5 MFAP5

7.18e-051791736ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ROR1 GAS6 LAMA5 ITLN2 BDNF GRAMD2A

7.18e-0517917361603117b52623663458a977c94bf7f9f6c1114b8
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

ARHGEF28 CDK5R1 DNAH12 NOM1 MME KNL1

7.41e-05180173685fc9b164147b28545e2397d32302eea03ef6346
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

ROR1 GAS6 LAMA5 ITLN2 AQP1 BDNF

7.41e-0518017362d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

7.41e-05180173692fb01b91261b3103454924cde56add337b41844
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

NPIPB4 ZNF618 GAS6 ZDBF2 PDE8B NT5DC2

7.41e-051801736be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

7.64e-051811736c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZYG11A ARHGEF28 SSTR2 MME ABCC2 SLC25A48

7.64e-0518117366980ea624151da32b7f537f263e40fcb87a02e81
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PTPMT1 OPN3 GCDH CHPT1 CCR6 CCDC180

7.87e-05182173603992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 ZNF618 FPR3 GAS6 FCGBP CCR6

8.11e-051831736bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 ZNF618 FPR3 GAS6 FCGBP CCR6

8.11e-051831736d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GPER1 ROR1 GAS6 LAMA5 ITLN2 BDNF

8.36e-051841736c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GPER1 ROR1 GAS6 LAMA5 ITLN2 BDNF

8.36e-0518417361ed558a88215b248431c524ea16f13d9022ae98c
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

8.36e-051841736797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

8.36e-05184173677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

8.36e-0518417362817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROR1 LAMA5 ITLN2 BDNF GRAMD2A PLCE1

8.61e-0518517361c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellILEUM-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PALD1 GPR65 GAS6 ATP13A2 NIBAN3 CDK5R1

8.61e-051851736308a98f111895071d8772bc010554471cc12fab2
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B

8.61e-0518517360563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR65 DUSP2 ZDBF2 ZAP70 NCDN CCR6

8.61e-0518517368314dc608bc837df3037e89afd9db39737374ebc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 GPR65 DOCK8 FPR3 MPEG1 DPEP2

8.87e-051861736e152bdd837366e3e0b8bcfdb4d53f0685f2e803a
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B

9.14e-051871736fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GPR65 DUSP2 ZAP70 TBC1D31 SYNE2 NCR1

9.14e-0518717366981b856187a2e689260ecb7d0a1193a374ee9b9
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ROR1 AQP1 SYNE2 MME ABCC2 SLC25A48

9.14e-051871736738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

NPIPB4 BTAF1 ANKRD36C MED13L SYNE2 DYNC1H1

9.41e-051881736ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 DUSP2 ZAP70 CCR6 NCR1

9.41e-051881736624426815b789f0f35c327b8c3c0c05ba3aa7d98
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

9.68e-05189173602c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

9.68e-051891736164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

9.68e-051891736407d8a59969d83f014600aae1a55092283a13970
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

9.68e-0518917360bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

9.68e-051891736a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK8 FPR3 MPEG1 RYR1 FCGBP AP2A2

9.68e-0518917362586f4088721c5debec86c2b211b739fd33713eb
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|356C / Donor, Lineage, Cell class and subclass (all cells)

PTPMT1 ARHGEF28 OPN3 ITIH5 PNPLA6 MME

9.97e-0519017364cce4ddb79b7751d0103e10f71156977e0c34439
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

1.03e-041911736bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellCOVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

1.03e-0419117369d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

ROR1 GAS6 LAMA5 ITLN2 BDNF TENT5B

1.03e-04191173666875b2ec2c510489407f3e433a90cdf74a15094
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 GAS6 ITLN2 BDNF TENT5B GRAMD2A

1.03e-041911736a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

1.03e-0419117366880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SSTR5 RYR1 AGL PKP1 ALDH7A1 KNL1

1.03e-0419117360f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCell(2)_Fibroblasts-(21)_Fibro-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

BICD2 ITIH5 TMEM196 MFAP5 ACKR3 PKP1

1.03e-0419117365ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

1.06e-041921736b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

NPIPB4 BTAF1 ANKRD36C ZAP70 IVNS1ABP SYNE2

1.06e-04192173647646d7e4990be85072987f92bf18d52f8da752e
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRC7 SPACA9 DNAH12 SPAG17 CCDC180 CFAP46

1.06e-0419217362d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OPN3 MPEG1 GPR55 NIBAN3 CDK5R1 ABCC2

1.06e-041921736faead5875a54fe8f1848ae36008aae4c0f7cb1c7
ToppCellproximal-3-Hematologic-Plasmacytoid_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OPN3 MPEG1 GPR55 NIBAN3 CDK5R1 ABCC2

1.06e-04192173686938c7d2bb1a7afb2b83828ca33dd137d366ec6
ToppCellASK452-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

GPR65 ZAP70 CNOT6 TBC1D31 AGL SYNE2

1.06e-041921736f04ee5aaa54c39b7493098fb3d2f78168d6b8060
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OPN3 MPEG1 GPR55 NIBAN3 CDK5R1 ABCC2

1.06e-041921736e3be395a995dc8c0ebdae754057cfa59a270cae0
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR65 NPIPB4 OPN3 GAS6 MPEG1 NIBAN3

1.09e-04193173630abf991ac17c18679ab7d633e7549c0ce841920
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PALD1 FPR3 GAS6 MPEG1 FCGBP NT5DC2

1.12e-04194173611ff53a748160570d2908ea9eb9779c038e5b676
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

1.12e-04194173674545942aded51a0f4ee96054b4ce12c4d99a8a0
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GPR65 DUSP2 ZAP70 SYNE2 NCR1 KNL1

1.12e-041941736f0707601883b234ed477c7704ca9a88efaefc3fd
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GPR65 DUSP2 ZAP70 SYNE2 NCR1 KNL1

1.12e-0419417368bfd7c5be518b81b17913139bcb3ebea01f48dd5
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

PALD1 SPAG4 OPN3 GAS6 MPEG1 NIBAN3

1.12e-0419417365f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

PALD1 OPN3 GAS6 MPEG1 ATP13A2 NIBAN3

1.12e-041941736c25fc353001cdf9fcd772da5a254c857e555eab8
ToppCelldistal-1-Hematologic-IGSF21+_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 ZNF618 FPR3 GAS6 CYTL1 FCGBP

1.12e-041941736f30c866e5f41ee79bdc6b6e08af962d62b199835
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-|Thalamus / BrainAtlas - Mouse McCarroll V32

DRC7 SPACA9 DNAH12 SPAG17 CCDC180

1.14e-041221735aca079f2f033cc1ac13c4ee02d490b6a514cbd5c
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--|Thalamus / BrainAtlas - Mouse McCarroll V32

DRC7 SPACA9 DNAH12 SPAG17 CCDC180

1.14e-041221735ac38130010f76648757eac700a8039f3960ddde3
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL|Thalamus / BrainAtlas - Mouse McCarroll V32

DRC7 SPACA9 DNAH12 SPAG17 CCDC180

1.14e-0412217357ab0b63244116e74c5783c3293cf08224d094d0a
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

ARHGEF28 CARMIL2 OBSCN KCNS2 FRMPD3

1.14e-0412217352aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellThalamus-Macroglia-CSF_related|Thalamus / BrainAtlas - Mouse McCarroll V32

DRC7 SPACA9 DNAH12 SPAG17 CCDC180

1.14e-041221735eb944243424460bf5c66aced3ed7b7a1b6486ac7
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)|Thalamus / BrainAtlas - Mouse McCarroll V32

DRC7 SPACA9 DNAH12 SPAG17 CCDC180

1.14e-0412217359b0d6b0a394560ff5aadcd3b21519c2393e6def8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 GPR65 DOCK8 FPR3 MPEG1 RYR1

1.15e-04195173691a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

ROR1 GAS6 LAMA5 ITLN2 BDNF GRAMD2A

1.15e-041951736569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellMacrophages-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DOCK8 ITIH5 PNPLA6 DPEP2 ACKR3 MME

1.15e-0419517362af46e87947c16a7c2c367637e606cfbb8a78528
DrugN-carbamylglutamate

SSTR1 SSTR2 SSTR3 SSTR5 ABCC8

2.93e-08131735CID000121396
DrugAC1O3HA7

SSTR1 SSTR2 SSTR3 SSTR5

4.77e-0861734CID006328526
DrugBim23268

SSTR1 SSTR2 SSTR3 SSTR5

1.11e-0771734CID005311026
DrugEe 581

SSTR1 SSTR2 SSTR3 SSTR5

2.20e-0781734CID003036100
DrugBIM 23034

SSTR1 SSTR2 SSTR3 SSTR5

2.20e-0781734CID005492589
DrugSomatostatin

SSTR1 SSTR2 SSTR3 SSTR5

2.20e-0781734ctd:D013004
DrugAC1Q5JP2

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID000134288
DrugTyr(3)-sms

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID000123864
DrugDepreotide

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID009898619
DrugCyclo Ss-8

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID003081285
DrugX Bb

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID000445281
DrugHexapeptide 4

SSTR1 SSTR2 SSTR3 SSTR5

3.94e-0791734CID000194954
DrugOctreotide

SSTR1 SSTR2 SSTR5

4.31e-0731733DB00104
DrugSeglitidum [latin]

SSTR2 SSTR3 SSTR5

4.31e-0731733CID003035423
DrugIBDU

SSTR1 SSTR2 SSTR3 SSTR5 AQP1

1.69e-06271735CID000022478
Drugthsat

SSTR1 SSTR2 SSTR3

1.72e-0641733CID000195015
DrugEdotreotide

SSTR1 SSTR2 SSTR3 SSTR5

2.18e-06131734CID000158782
DrugSRA 880

SSTR1 SSTR2 SSTR3 SSTR5

3.04e-06141734CID005311376
DrugL-817,818

SSTR1 SSTR2 SSTR3 SSTR5

4.12e-06151734CID005311375
DrugL-796,778

SSTR1 SSTR2 SSTR3 SSTR5

5.46e-06161734CID005311373
Drugruthenium

SSTR1 SSTR2 SSTR3 SSTR5 RYR1 SPAG17 OGA

7.60e-06941737CID000023950
DrugCycam

SSTR1 SSTR2 SSTR3 SSTR5

9.07e-06181734CID000122080
DrugL-803,087

SSTR1 SSTR2 SSTR3 SSTR5

9.07e-06181734CID005311374
Drugpasireotide

SSTR1 SSTR2 SSTR3 SSTR5

9.07e-06181734ctd:C517782
DrugZwittergent 3-12

SSTR1 SSTR2 SSTR3 SSTR5

9.07e-06181734CID000084703
DrugBIM-23027

SSTR2 SSTR3 SSTR5

1.48e-0571733CID005311025
DrugN-N-C

SSTR1 SSTR2 SSTR3 SSTR5 ABCC8

1.62e-05421735CID005278688
DrugL-779,976

SSTR1 SSTR2 SSTR3 SSTR5

1.74e-05211734CID005311372
Drugmetaiodobenzylguanidine

SSTR1 SSTR2 SSTR3 SSTR5

2.12e-05221734CID000060860
DrugN1-aminopropylagmatine

SSTR1 SSTR2 SSTR3 SSTR5

2.12e-05221734CID000541551
Druglanreotide

SSTR2 SSTR3 SSTR5

2.35e-0581733ctd:C060347
DrugANB-NOS

SSTR1 SSTR2 SSTR3 SSTR5

2.55e-05231734CID003080866
Drugbutamifos

SSTR1 SSTR2 SSTR3 SSTR5

4.22e-05261734CID000037419
DrugRc 121

SSTR1 SSTR2 SSTR3 SSTR5

4.22e-05261734CID000127388
Drugeniluracil

SSTR1 SSTR2 SSTR3 SSTR5

4.93e-05271734CID000043157
Druglanreotide

SSTR1 SSTR2 SSTR3 SSTR5

4.93e-05271734CID000071348
Drugdtpa-sms

SSTR1 SSTR2 SSTR3 SSTR5

5.72e-05281734CID000072128
Drugcyclic d(ApAp

RYR1 ALDH7A1

5.74e-0521732CID000188955
DrugAC-7954

UTS2R SSTR3

5.74e-0521732CID009797568
Drug5-HIAA

SSTR1 SSTR2 SSTR3 SSTR5 BDNF ABCC8 ALDH7A1

5.94e-051291737CID000001826
DrugAC1L2HGV

SSTR1 SSTR2 SSTR3 SSTR5

6.59e-05291734CID000072127
DrugTt 232

SSTR1 SSTR2 SSTR3 SSTR5

7.56e-05301734CID000164469
DrugAN-201

SSTR1 SSTR2 SSTR3 SSTR5

8.63e-05311734CID000119196
Drug111In-pentetreotide

SSTR1 SSTR2 SSTR3 SSTR5

8.63e-05311734CID003081912
DrugAC1LA7UO

SSTR1 SSTR2 SSTR3 SSTR5

9.80e-05321734CID000483172
DrugCGS 8216

SSTR1 SSTR2 SSTR3 SSTR5

1.11e-04331734CID000104916
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A

DUSP2 LAMA5 SOCS6 ATP13A2 FBXL7 PDE8B MAP2K3 AP3D1

1.23e-0419417383570_DN
Drugvanadyl

DUSP2 SSTR2 SSTR3 MAP3K5 PTK2B PDE8B NCR1 MAP2K3 DYNC1H1 ALDH7A1

1.26e-0430717310CID000061671
Drugamino acetate

CPS1 SSTR1 SSTR2 SSTR3 SSTR5

1.37e-04651735CID000177069
Drugdimefox

SSTR1 SSTR2 SSTR3 SSTR5

1.40e-04351734CID000008264
DrugDiazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A

SPAG4 ITFG2 ATG13 MAP3K5 AP2A2 UTP25 TUBGCP3 OGA

1.41e-0419817387168_DN
DiseaseGrand Mal Status Epilepticus

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0311335
DiseaseStatus Epilepticus, Subclinical

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0751522
DiseaseSimple Partial Status Epilepticus

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0751524
DiseaseNon-Convulsive Status Epilepticus

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0751523
DiseasePetit mal status

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0270823
DiseaseComplex Partial Status Epilepticus

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

9.08e-08671637C0393734
DiseaseStatus Epilepticus

SSTR1 SSTR2 SSTR3 SSTR5 BDNF PTK2B ABCC2

1.01e-07681637C0038220
DiseaseNeuroendocrine Tumors

SSTR1 SSTR2 SSTR3

2.64e-05111633C0206754
DiseaseParkinson's disease (implicated_via_orthology)

SSTR1 SSTR2 SSTR3 SSTR5 ATP13A2 EIF4G1 MAP2K3

2.81e-051571637DOID:14330 (implicated_via_orthology)
Diseaseretinal disease (implicated_via_orthology)

CHPT1 MAP2K3

4.48e-0461632DOID:5679 (implicated_via_orthology)
Diseasewaist-hip ratio

BICD2 NUP85 CYTL1 AQP1 ATP13A2 BDNF MEP1A PTPDC1 PDE8B ABCC8 SBF2 SYNE2 MAP2K3 AP3D1 SMAD2 KNL1 PLCE1

4.66e-04122616317EFO_0004343
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NUP85 XPO5 PLCE1

6.02e-04301633C1868672
Diseasetotal blood protein measurement

ZSWIM8 DNAJC13 ZNF618 CPS1 MAP3K5 CC2D2B SBF2 SLC25A10 PLCE1

9.19e-044491639EFO_0004536
DiseaseX-21467 measurement

CPS1 ABCC2

1.06e-0391632EFO_0020007
Diseasecortical surface area measurement

BICD2 PALD1 DNAJC13 ATG13 ROR1 MED13L CPS1 ATP13A2 ITIH5 CNOT6 FBXL7 ACKR3 NT5DC2 VPS35L SPAG17 MTCH2 PLCE1

1.29e-03134516317EFO_0010736
Diseasecystic kidney disease (implicated_via_orthology)

EPHB4 LAMA5

1.33e-03101632DOID:2975 (implicated_via_orthology)
DiseaseCombined immunodeficiency

CARMIL2 DOCK8 ZAP70

1.51e-03411633C0494261
Diseasemicrofibrillar-associated protein 2 measurement

ATP13A2 MFAP5

1.61e-03111632EFO_0801801
DiseaseCharcot-Marie-Tooth disease

SBF2 MME DYNC1H1

1.62e-03421633cv:C0007959
Diseaseepilepsy (implicated_via_orthology)

BDKRB2 CDK5R1 SBF2 DYNC1H1 ALDH7A1

2.16e-031631635DOID:1826 (implicated_via_orthology)
Diseaseglutaroyl carnitine measurement

GCDH CPS1

2.27e-03131632EFO_0021005
Diseasestatus epilepticus (biomarker_via_orthology)

AQP1 PTK2B ABCC8 ABCC2

2.33e-031001634DOID:1824 (biomarker_via_orthology)
DiseaseSeizures, Focal

SSTR2 BDNF ABCC2 DYNC1H1

2.69e-031041634C0751495
DiseaseOrofacial cleft

OR9K2 UTP25 CHPT1

2.84e-03511633HP_0000202
Diseasecorpus callosum posterior volume measurement

BICD2 ATP13A2 FBXL7

3.00e-03521633EFO_0010298
Diseasenervous system disorder

BDNF PNPLA6 ABCC2

3.17e-03531633C0027765
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD2 KNL1

3.46e-03161632DOID:0070296 (is_implicated_in)
DiseaseMultiple congenital anomalies

GPER1 AFF4

3.91e-03171632C0000772
Diseaseglutarylcarnitine (C5-DC) measurement

GCDH CPS1

3.91e-03171632EFO_0800030
DiseaseCharcot-Marie-Tooth disease type 2

MME DYNC1H1

3.91e-03171632cv:C0270914
Diseasemigraine disorder, systolic blood pressure

HIC1 PLCE1

4.38e-03181632EFO_0006335, MONDO_0005277
Diseaseserum homoarginine measurement

WDR25 CPS1

5.40e-03201632EFO_0005421

Protein segments in the cluster

PeptideGeneStartEntry
MNLLIISFDRYFCVT

CHRM4

121

P08173
DLEQCYFSTRMSRIS

COP1

366

Q8NHY2
LVMRILYLDSSEICF

ESYT1

591

Q9BSJ8
LYSSICFLMLVSIDR

BDKRB2

141

P30411
SCAYRINLAFMSTRQ

ATG13

186

O75143
VVFLYMLCRDVISSE

CDK5R1

201

Q15078
SQCRTTQSYVRALTM

BDNF

206

P23560
LRAMFATRCDEYITQ

BICD2

746

Q8TD16
YMRRSTCTINYSKDL

ALDH7A1

516

P49419
LRVDCTFSYLEVQAM

CARMIL2

61

Q6F5E8
ACSASDQMRRYRTAF

EVX1

176

P49640
RRTETMFNACLYFKS

AJM1

671

C9J069
SCQISIFRALMYIIA

AQP1

86

P29972
LTCISMDRYIAIVQA

CCR6

136

P51684
RETNLRYLALESMCT

AP2A1

341

O95782
QMASTRLRLCTTLYQ

CFAP46

466

Q8IYW2
SVTRVLVALEMYSCN

CFAP46

891

Q8IYW2
NFRSSMYIEILISLC

DOP1A

1446

Q5JWR5
ARLVDYMICQSLISV

DNHD1

521

Q96M86
RIQYLNCSLDRVSMT

CCDC180

1186

Q9P1Z9
YQIRMESRACESTRL

DHX29

661

Q7Z478
ASLCRQMTYSLTRFA

SLC25A10

66

Q9UBX3
SLRSSYCSMLRNVDA

CC2D2B

641

Q6DHV5
FNASIMTDLVRYTRQ

AFF4

1136

Q9UHB7
ETNLRYLALESMCTL

AP2A2

341

O94973
VVERVDSCASMYSRS

AP3D1

1096

O14617
LRSMVQFIGRESKYC

MTCH2

146

Q9Y6C9
TSMTRLYYRDASACV

RAB29

71

O14966
RVMELTYSNCRTTED

MPEG1

61

Q2M385
DLALMQTCYREAERS

NIBAN3

431

Q86XR2
LTYRFQTCLTMQEVF

PALD1

596

Q9ULE6
ECNDNTMRAFTYRTR

ANO10

91

Q9NW15
YVDNMACRLARLLVT

ARHGEF28

91

Q8N1W1
SGQRLETEMQSYRCR

ANKRD36C

1456

Q5JPF3
ETEMQSYRCRLNAAL

ANKRD36C

1461

Q5JPF3
LYSVQMSTRLCTQLV

OR9K2

156

Q8NGE7
MAEIQSRLAYVSCVR

PNPLA6

1196

Q8IY17
RLACTDTYRLQFMVT

OR4F21

186

O95013
FDILCITNSYTMILR

OR52N4

211

Q8NGI2
LSSQFMAYIEQRRIS

LRCH3

401

Q96II8
TFFRDLSAVYEMCRL

MED13L

1436

Q71F56
NTRNLLTTDFVCMRF

MAGEE2

221

Q8TD90
TFYCRLDTATSMFLL

NCR1

141

O76036
AARRSMIDDTYQCLT

NCDN

146

Q9UBB6
VYATLRFTMLECLSL

EPHB4

86

P54760
ISRYAFTTVSCRMLN

ITIH5

61

Q86UX2
LSRMDVTSCISYRNF

IVNS1ABP

126

Q9Y6Y0
EYFRITASNRMYSLC

SBF2

1136

Q86WG5
VTLETVLRCLQARYM

MYO19

46

Q96H55
DACGMRFTRQYRLTE

HIC1

566

Q14526
LVVSLMCSARAEYSN

EDAR

16

Q9UNE0
AGFRMTRTVNTICYL

FPR3

51

P25089
FCLSRENLASDMYLI

LARP4B

166

Q92615
SYSRLANELRVSCME

DCAF4L1

41

Q3SXM0
VMIVRRYSISSSVCS

CCDC195

81

A0A1B0GUA6
ISRSATICLAYLMQS

DUSP2

261

Q05923
QTYELMRCLEDLTSR

NUP85

596

Q9BW27
VVMSHDRYVAVCRSL

OR2W5P

116

A6NFC9
FEAREISLYSCIVQM

OR51F1

96

A6NGY5
VLLSMSIDRYVAVCN

OR51G1

116

Q8NGK1
VAMRRRCSQFVNYSK

OR4F6

296

Q8NGB9
HYSTIMNRRLCVIFV

OR4K1

131

Q8NGD4
RRFMENSSIIACYNE

PDE8B

236

O95263
IFMSACQDQTIRLYD

DCAF11

186

Q8TEB1
FYRRQKQLESAMRSC

KCNS2

416

Q9ULS6
ACTAYVDFMISVARL

MME

241

P08473
IVMTYRLCSEQLSSQ

DNAH12

1406

Q6ZR08
ILYTCRQDDMEITRS

KNL1

931

Q8NG31
VFTRECMSHYLRVFN

TUBGCP3

651

Q96CW5
SVQMFYVSTSRQLRR

ABCC2

1136

Q92887
IACYLVFATRMTADQ

PTPDC1

201

A2A3K4
RCRSSSYTRQEFVDM

LAMA5

1636

O15230
TCYSRMRALSQEITR

CYTL1

26

Q9NRR1
ARKLYTIMNSFCRRD

CYTL1

96

Q9NRR1
MIISRYLLSVCGFRF

NPIPB4

651

C9JG80
TICFISMDRFLAIRY

GPR55

111

Q9Y2T6
TIMSDRICYQLIISS

OR6C76

131

A6NM76
MRSVSYVQRVALEFS

ITFG2

1

Q969R8
TSLRRMYIVNKEICS

MFAP5

111

Q13361
FCRDMTFDLRNRTYV

PATE3

71

B3GLJ2
RDSRTDTVSYVFRNM

OBSCN

5936

Q5VST9
RSRSATMVAAYLIQV

PTPMT1

136

Q8WUK0
LYSIRMLRCVEDLQT

OPN3

226

Q9H1Y3
QFCLTYESAMTRLFL

CPT1C

581

Q8TCG5
AMTVCTLYAQSRLRR

ATP13A2

476

Q9NQ11
TSMEYCIIEVNARLS

CPS1

706

P31327
LFIRRLSCEQLGTYM

IGSF23

96

A1L1A6
RAVLSACSSYFRAMF

KLHL24

81

Q6TFL4
VTRSQACATLYLLMR

DOCK8

1521

Q8NF50
SVRFMATQCFATLIR

BTAF1

1201

O14981
LIRDTFRTYCQERLM

GCDH

66

Q92947
QISIRYLDMTDCFVL

FBXL7

271

Q9UJT9
RRFDFMGTCVYVLAQ

FCGBP

1266

Q9Y6R7
SELVSFCYLHMREQR

FRMPD3

556

Q5JV73
ALNEFRTTICNLYTM

FNIP1

396

Q8TF40
VTAFYRGCMTLEVNR

GAS6

636

Q14393
VEFLYCDLASMTSIR

DHRSX

96

Q8N5I4
SIFFLTCMSVDRYLS

ACKR3

131

P25106
FTDTRYIIGMLERCT

DNAJC13

891

O75165
SYCSQAMFRIRILEQ

DRC7

826

Q8IY82
NTLVRALMTAVCYSA

EIF4G1

1476

Q04637
FNYLCIMDSFSTRAR

MBOAT4

26

Q96T53
RTMTRLCFLLFFSVA

ITLN2

6

Q8WWU7
DRCYLTMTQALEARL

DYNC1H1

1886

Q14204
IRRMCASYSELELVT

DPEP2

156

Q9H4A9
TFVMYNCARLATLFE

DALRD3

401

Q5D0E6
RFTELVCSLSDVYQM

PTK2B

671

Q14289
CFLVMSSSYLAFRIS

GRAMD2A

321

Q8IUY3
TSTRLDDRVYAMCQI

SEC24B

1091

O95487
FTTYSERLRICQMFV

SPACA6

31

W5XKT8
YCNSSTDRRVLLMFL

SPACA9

56

Q96E40
SACRSRRSMLSEYIV

RYR1

1721

P21817
FSTTEMALALNRYLC

RYR1

2541

P21817
DRTRPTALFSVMCYN

CNOT6

181

Q9ULM6
SSCIFMYIKTSARER

OR6C75

251

A6NL08
LDINMRTVDCFYTVT

MAP2K3

111

P46734
LLLTVMSFDRYTAIC

OR14A16

111

Q8NHC5
RLACTDTYRLQFMVT

OR4F3;

186

Q6IEY1
VRESFSMANNIILYC

MAP3K5

171

Q99683
DILSSACYTVRNLMA

PKP1

656

Q13835
RRYTISSALNLMQIC

RPP30

166

P78346
SQSFLYRQVRRMTAV

PUSL1

226

Q8N0Z8
MCESYSRSLLRVSVA

TAF3

1

Q5VWG9
RYLMGETQLCTTRCV

UTP23

51

Q9BRU9
FYSEICNMLRATNRG

UTP25

696

Q68CQ4
MFTSIYCLTVLSVDR

SSTR1

141

P30872
SFLLMTVVAYNICSR

TBC1D31

601

Q96DN5
IFCLTVMSVDRYLAV

SSTR3

131

P32745
TCLMDRYQTLLRQLS

SYNE2

2016

Q8WXH0
TRLSNCANRTILYDM

OGA

626

O60502
YEVDRRMSDTFCTLS

PLCE1

191

Q9P212
VCRVMEYCSRELILS

FASTKD3

371

Q14CZ7
YIALARAMRCSLFRT

GPER1

156

Q99527
AMAICYSRIVLSVSR

GNRHR2

131

Q96P88
SAIDLERLNRMYNCT

MEP1A

246

Q16819
SMSYCDESRLSNLLR

nan

136

Q6P435
LRTFGRLCLYDMIQS

TEN1

26

Q86WV5
RRNIFCTIMTSEDFL

NOM1

656

Q5C9Z4
NTLSCIRVVYRRESM

SLC25A48

41

Q6ZT89
TRTLMDIYVQCLSAL

INTS5

186

Q6P9B9
SVFCLTVMSVDRYLA

SSTR5

126

P35346
SMYREVCSIRFLFTA

SPAG4

156

Q9NPE6
FCLTVMSIDRYLAVV

SSTR2

131

P30874
RQVKCMRVESSRYAT

SPAG17

1486

Q6Q759
MRVESSRYATVIANC

SPAG17

1491

Q6Q759
TDVRALQRYMCSRFF

TENT5B

296

Q96A09
AMRALTNYQRLCEAF

ABCC8

256

Q09428
YQDCTFFTRKEIMRL

CIB3

16

Q96Q77
CYALIRLLESFETMA

NCAPD2

121

Q15021
RCSTRITVYMVLNEC

CLCA3P

186

Q9Y6N3
DMVIYFSALCLQISR

CHPT1

361

Q8WUD6
IACARFIGNRTVYME

ROR1

176

Q01973
FLTVEQRMRACYYSL

ZAP70

586

P43403
TCRLASYEQRRMFSE

TMEM196

131

Q5HYL7
RSLYRDVMLETCRNL

ZNF77

26

Q15935
FVMSEIRTVYVTDCR

ZNF618

606

Q5T7W0
YERIFSMCVDSRSVL

VPS35L

246

Q7Z3J2
RNFSTDFYSLIMVCV

XKR7

406

Q5GH72
GFEAVYQLTRMCTIR

SMAD2

401

Q15796
TSMRSIIFANYIARD

RRAGA

21

Q7L523
ANSDIFLYEILRSMC

TRIM49C

296

P0CI26
TMSSRLIYTLRCGVF

TMEM79

231

Q9BSE2
RSSFTMLQRICTLYK

ZNF840P

191

A6NDX5
YDLRSSSCLQQRERM

ZDBF2

2326

Q9HCK1
LNRARMSFCVYSILG

XPO5

716

Q9HAV4
STQAVCRGYLMRVEF

MYH13

791

Q9UKX3
VVTMTLCYARISREL

PROKR2

236

Q8NFJ6
RLVRFSDLYMASLSC

NT5DC2

461

Q9H857
MYRITVALTSLNCVA

GPR65

271

Q8IYL9
RMLLQSSEGRCVYIT

SNRNP200

1366

O75643
VLEVICSRMRYISSQ

SNRNP200

1466

O75643
AYNVAVMFDRCRVTS

ZSWIM8

171

A7E2V4
LAQRTLYREVMLETC

ZNF550

31

Q7Z398
TCRSLRAVASMYVYV

UTS2R

76

Q9UKP6
RVLMYSFRTASRACT

WDR25

496

Q64LD2
NSLLCSREMEVSYFA

ZYG11A

606

Q6WRX3
VSRFMQVRSLQYLCR

SOCS6

491

O14544
MTQILERLCRFDYLT

PPIP5K1

71

Q6PFW1
MAVRFTTRSCIGRYN

ZPBP2

146

Q6X784
CFSQLMLYAERAEAR

TMEM101

31

Q96IK0
YDTLMFCASRNTDRI

ZRANB3

731

Q5FWF4
YRRFGCTVDMNIALT

AGL

341

P35573
SALVFFSCRTDMPYR

NAGA

336

P17050