Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT5 KRT6A KRT81 KRT83 KRT86

2.79e-05431665GO:0030280
HumanPhenoPerifollicular hyperkeratosis

KRT81 KRT83 KRT86

5.00e-064563HP:0007468
HumanPhenoAbnormal perifollicular morphology

KRT81 KRT83 KRT86

2.46e-056563HP:0031285
MousePhenoincreased salivary gland tumor incidence

GON4L PER2 YY1AP1

8.12e-0651323MP:0010318
MousePhenoincreased mouth tumor incidence

GON4L PER2 YY1AP1

1.61e-0561323MP:0003750
MousePhenoincreased facial tumor incidence

GON4L PER2 YY1AP1

2.80e-0571323MP:0008018
MousePhenolethality throughout fetal growth and development, complete penetrance

NCOA6 GGNBP2 BICRA ATG13 PKD1L1 AMBRA1 TSC2 RUNX1 DICER1 MTF1 PALLD

3.94e-0526313211MP:0011099
MousePhenoincreased salivary adenocarcinoma incidence

GON4L YY1AP1

8.85e-0521322MP:0000621
DomainKeratin_2_head

KRT5 KRT6A KRT81 KRT83 KRT86

1.88e-06241655IPR032444
DomainKeratin_2_head

KRT5 KRT6A KRT81 KRT83 KRT86

1.88e-06241655PF16208
DomainKeratin_II

KRT5 KRT6A KRT81 KRT83 KRT86

2.87e-06261655IPR003054
DomainL_dom-like

ERBB2 LRRC75B ECM2 TLR7 LRRC70 SKP2 ERBIN LRIG3 CMIP SLITRK5 CD180 GP9

3.61e-0532816512IPR032675
DomainFAM193_C

FAM193B FAM193A

7.76e-0521652PF15914
DomainDUF1088

NBEA LRBA

7.76e-0521652IPR010508
DomainDUF1088

NBEA LRBA

7.76e-0521652PF06469
DomainFAM193_C

FAM193B FAM193A

7.76e-0521652IPR031802
DomainFAM193

FAM193B FAM193A

7.76e-0521652IPR029717
Domain-

LRRC75B ECM2 TLR7 LRRC70 SKP2 ERBIN LRIG3 CMIP SLITRK5 CD180 GP9

1.37e-04321165113.80.10.10
DomainLRR_8

ECM2 TLR7 LRRC70 ERBIN LRIG3 SLITRK5 CD180 GP9

1.42e-041711658PF13855
DomainCys-rich_flank_reg_C

TLR7 LRRC70 LRIG3 SLITRK5 CD180 GP9

1.46e-04901656IPR000483
DomainLRRCT

TLR7 LRRC70 LRIG3 SLITRK5 CD180 GP9

1.46e-04901656SM00082
DomainLeu-rich_rpt

LRRC75B ECM2 TLR7 LRRC70 SKP2 ERBIN LRIG3 SLITRK5 CD180 GP9

1.52e-0427116510IPR001611
DomainLRRCT

TLR7 LRIG3 CD180 GP9

1.74e-04321654PF01463
DomainGYF

GIGYF1 GIGYF2

2.31e-0431652PS50829
DomainGYF

GIGYF1 GIGYF2

2.31e-0431652SM00444
DomainGYF

GIGYF1 GIGYF2

2.31e-0431652PF02213
Domain-

GIGYF1 GIGYF2

2.31e-04316523.30.1490.40
DomainIntermediate_filament_CS

KRT5 KRT6A KRT81 KRT83 KRT86

2.35e-04631655IPR018039
DomainFilament

KRT5 KRT6A KRT81 KRT83 KRT86

4.12e-04711655SM01391
DomainIF

KRT5 KRT6A KRT81 KRT83 KRT86

4.40e-04721655PS00226
DomainGYF

GIGYF1 GIGYF2

4.60e-0441652IPR003169
DomainFilament

KRT5 KRT6A KRT81 KRT83 KRT86

4.69e-04731655PF00038
DomainIF

KRT5 KRT6A KRT81 KRT83 KRT86

5.64e-04761655IPR001664
DomainLRR_1

ECM2 TLR7 LRRC70 SKP2 ERBIN LRIG3 SLITRK5 CD180

7.47e-042191658PF00560
DomainDUF4704

NBEA LRBA

7.62e-0451652IPR031570
DomainDUF4704

NBEA LRBA

7.62e-0451652PF15787
DomainLRR_TYP

ECM2 TLR7 LRRC70 ERBIN LRIG3 SLITRK5 CD180

1.01e-031771657SM00369
DomainLeu-rich_rpt_typical-subtyp

ECM2 TLR7 LRRC70 ERBIN LRIG3 SLITRK5 CD180

1.01e-031771657IPR003591
DomainPAS_fold_3

KCNH8 HIF3A PER2

1.05e-03231653IPR013655
DomainPAS_3

KCNH8 HIF3A PER2

1.05e-03231653PF08447
DomainPH_BEACH

NBEA LRBA

1.14e-0361652PF14844
DomainUBQ-conjugating_AS

UBE2C UBE2A UBE2B

1.35e-03251653IPR023313
DomainPAC

KCNH8 HIF3A PER2

1.52e-03261653IPR001610
DomainPAC

KCNH8 HIF3A PER2

1.52e-03261653SM00086
DomainPDZ

SYNPO2 PPP1R9A SYNPO2L MPDZ ERBIN AHNAK2

1.59e-031411656PF00595
DomainLRRNT

TLR7 LRRC70 LRIG3 SLITRK5 GP9

1.78e-03981655IPR000372
DomainLRRNT

TLR7 LRRC70 LRIG3 SLITRK5 GP9

1.78e-03981655SM00013
DomainPDZ

SYNPO2 PPP1R9A SYNPO2L MPDZ ERBIN AHNAK2

2.04e-031481656SM00228
DomainLRR

ECM2 TLR7 LRRC70 ERBIN LRIG3 SLITRK5 CD180

2.09e-032011657PS51450
DomainPH-BEACH_dom

NBEA LRBA

2.10e-0381652IPR023362
Domain-

NBEA LRBA

2.10e-03816522.30.29.40
DomainPH_BEACH

NBEA LRBA

2.10e-0381652PS51783
Domain-

SYNPO2 PPP1R9A SYNPO2L MPDZ ERBIN AHNAK2

2.18e-0315016562.30.42.10
DomainPDZ

SYNPO2 PPP1R9A SYNPO2L MPDZ ERBIN AHNAK2

2.25e-031511656PS50106
Pubmed

Human transcription factor protein interaction networks.

NOL4 NCOA6 CNOT11 HIVEP1 ESS2 GATAD2A FOXP2 BICRA UBR4 GON4L ISX CCT4 GIGYF1 TNRC6C ANKHD1 ERBIN IKZF5 NOL4L EIF4ENIF1 ZFP91 GIGYF2 ZFHX3 YY1AP1 HERC2 PCDH7 ASF1A ZMYM3 FILIP1L

3.76e-1014291702835140242
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NCOA6 ERBB2 CRTC3 HIVEP1 ATG13 USP43 MPDZ TSC2 GIGYF1 PLEKHG2 ERBIN EPN2 ANLN GIGYF2 DDX41 PLEKHA7 PCDH7 PALLD MAP3K2 AHNAK2

9.60e-098611702036931259
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NOL4 ERBB2 GATAD2A FOXP2 BICRA TAF1C AMBRA1 GIGYF1 ITGA3 ANKHD1 ELL3 DICER1 LRIG3 EIF4ENIF1 BRDT ZFP91 CAPRIN2 ASPM ZFHX3 DDX41 ZMYM3 BAHCC1

3.13e-0811161702231753913
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ROR1 GIGYF1 ERBIN FAM193A EIF4ENIF1 NUFIP2 TENM1 GIGYF2 LRBA PLEKHA7 AHNAK2

8.03e-082631701134702444
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT83 KRT86

1.15e-073170325557232
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT83 KRT86

1.15e-07317031372089
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT83 KRT86

1.15e-07317031712823
Pubmed

UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.

UBR4 UBE2A UBE2B

1.15e-073170338182926
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CLSTN3 ATG13 PPP1R9A GON4L TNRC6C ERBIN LRIG3 PER2 TLN1 NUFIP2 GIGYF2 YY1AP1 ZMYM3

1.21e-074071701312693553
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B NCOA6 ERBB2 BICRA UBR4 MED14 AMBRA1 TSC2 TNRC6C ITGA3 ZNF236 ANKHD1 SLC29A2 TNRC18 EIF4ENIF1 PER2 TLN1 LRBA HERC2 AHNAK2 BAHCC1

1.22e-0711051702135748872
Pubmed

Keratins of the human hair follicle.

KRT81 KRT83 KRT86

4.57e-074170315797458
Pubmed

A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis.

UBE2A UBE2B ASF1A

4.57e-074170326336826
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

HIVEP1 KRT81 SGTA TAF1C PPP1R9A USP29 USP43 MPDZ AMBRA1 SKP2 DICER1 TBL3 NPLOC4 PPP5C NUFIP2 GIGYF2 HERC2 DDX41 PLEKHA7

5.49e-0710051701919615732
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

PPP1R9A ROR1 USP43 ITGA3 SLC29A2 ERBIN EPN2 IFNGR1 CDKL5 CD44 LRBA STX7 PLEKHA7 PCDH7

9.08e-075691701430639242
Pubmed

Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.

KRT5 KRT6A KRT81 KRT86

9.58e-0716170412399393
Pubmed

Comprehensive analysis of keratin gene clusters in humans and rodents.

KRT6A KRT81 KRT83 KRT86

9.58e-0716170415085952
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CNOT11 GGNBP2 TAF1C PPP1R9A MED14 GON4L MPDZ CCT4 ANKHD1 ERBIN DICER1 TBL3 EPN2 EIF4ENIF1 ANLN TLN1 NUFIP2 ZFP91 ZFHX3 HERC2 PLEKHA7 ASF1A ZMYM3

1.21e-0614971702331527615
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOA6 CRTC3 SYNPO2 ESS2 BICRA UBR4 TNRC18 FAM193A EIF4ENIF1 DPPA4 TLN1 PLEKHA7

1.54e-064301701235044719
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CRTC3 NELFA PPP1R9A MPDZ TSC2 GIGYF1 SKP2 FAM193A EIF4ENIF1 GIGYF2 PLEKHA7 MAP3K2

2.25e-064461701224255178
Pubmed

GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.

GIGYF1 EIF4ENIF1 GIGYF2

2.27e-066170328698298
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

KRT5 KRT6A CRTC3 ESS2 GATAD2A NELFA NUFIP2 CD44 LRBA AHNAK2

2.33e-062981701030737378
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

KRT6A CNOT11 TAF1C ANKHD1 DICER1 THOC6 FAM193A EIF4ENIF1 TLN1 NUFIP2 ZFP91 CD44 GIGYF2 PALLD AHNAK2

3.05e-067241701536232890
Pubmed

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.

GIGYF1 EIF4ENIF1 GIGYF2

3.96e-067170322751931
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

GGNBP2 GON4L MPDZ AMBRA1 GIGYF1 ANKHD1 DICER1 NPLOC4 RAD54B GIGYF2 YY1AP1 PZP PCDHGC3 PALLD

4.25e-066501701438777146
Pubmed

A human MAP kinase interactome.

KRT5 CRTC3 SYNPO2 HIVEP1 BICRA NCKAP5 ERBIN PAK3 GIGYF2 YY1AP1 HERC2 MAP3K2

5.40e-064861701220936779
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA6 HIVEP1 NELFA SGTA MED14 RUNX1 ERBIN NOL4L ANLN ZFP91 GIGYF2 YY1AP1 DDX41 PCDH7 ZMYM3

6.80e-067741701515302935
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NOL4 HIVEP1 UBR4 ANKHD1 NOL4L FAM193A EIF4ENIF1 GIGYF2 ZFHX3 LRBA ZMYM3

7.42e-064181701134709266
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA6 HIVEP1 ESS2 GATAD2A NELFA BICRA MED14 CCT4 RUNX1 IKZF5 NOL4L TNRC18 PPP5C ANLN TLN1 ZFP91 DDX41 ZMYM3

8.51e-0611031701834189442
Pubmed

Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.

GIGYF1 EIF4ENIF1 GIGYF2

9.43e-069170331439631
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

NCOA6 CNOT11 GATAD2A MED14 AHNAK2

1.06e-0559170528813667
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ERBB2 ROR1 TLR7 ITGA3 SLITRK5 IMPG2

1.08e-05101170623382219
Pubmed

New consensus nomenclature for mammalian keratins.

KRT5 KRT6A KRT81 KRT83 KRT86

1.47e-0563170516831889
Pubmed

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.

CNOT11 ANKHD1 EIF4ENIF1 TLN1 NUFIP2 GIGYF2

1.50e-05107170630995489
Pubmed

The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development.

UBE2C EOMES ASPM

1.84e-0511170338199563
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

KRT5 ATG13 VPS13C PKD1L1 RNF135 CCT4 PLEKHG2 TNRC6C CNTLN EIF4ENIF1 TLN1 GIGYF2 HERC2 DDX41 PLEKHA7

2.12e-058531701528718761
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CRTC3 GATAD2A AMBRA1 GIGYF1 ANKHD1 DICER1 TNRC18 FAM193A EIF4ENIF1 NUFIP2 GIGYF2 DDX41 MAP3K2

2.23e-056551701335819319
Pubmed

AR imposes different effects on ZFHX3 transcription depending on androgen status in prostate cancer cells.

AR ZFHX3

2.38e-052170234953044
Pubmed

AR pathway activity correlates with AR expression in a HER2-dependent manner and serves as a better prognostic factor in breast cancer.

ERBB2 AR

2.38e-052170231933152
Pubmed

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

UBE2A UBE2B

2.38e-052170215169909
Pubmed

Prognostic significance of CD44 and c-erb-B2 protein overexpression in patients with gastric cancer.

ERBB2 CD44

2.38e-052170223435135
Pubmed

Correlation between androgen receptor expression and pathological response rate in pre-operative HER2-positive breast cancer patients.

ERBB2 AR

2.38e-052170237264265
Pubmed

Elevated levels of HER-2/neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.

ERBB2 AR

2.38e-052170218324648
Pubmed

The transcriptional regulator GON4L is required for viability and hematopoiesis in mice.

GON4L YY1AP1

2.38e-052170233864850
Pubmed

The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.

UBE2A UBE2B

2.38e-052170211885984
Pubmed

TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner.

TLR7 IFNGR1

2.38e-052170232849556
Pubmed

Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research.

ISX BCO2

2.38e-052170237225015
Pubmed

Expression of sarcosine metabolism-related proteins in estrogen receptor negative breast cancer according to the androgen receptor and HER-2 status.

ERBB2 AR

2.38e-052170226339363
Pubmed

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.

UBE2A UBE2B

2.38e-052170231683936
Pubmed

Zfhx3-mediated genetic ablation of the SCN abolishes light entrainable circadian activity while sparing food anticipatory activity.

PER2 ZFHX3

2.38e-052170234632336
Pubmed

A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.

KRT81 KRT86

2.38e-05217029402962
Pubmed

cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis.

MYF5 CRTC3

2.38e-052170229784793
Pubmed

RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells.

ERBB2 RUNX1

2.38e-052170229686309
Pubmed

RUNX1 Is Regulated by Androgen Receptor to Promote Cancer Stem Markers and Chemotherapy Resistance in Triple Negative Breast Cancer.

RUNX1 AR

2.38e-052170236766786
Pubmed

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.

GON4L YY1AP1

2.38e-052170220530203
Pubmed

Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation.

KRT5 KRT6A

2.38e-052170235527047
Pubmed

miRNAs are required for generating a time delay critical for the circadian oscillator.

DICER1 PER2

2.38e-052170224094851
Pubmed

CD44 collaborates with ERBB2 mediate radiation resistance via p38 phosphorylation and DNA homologous recombination pathway in prostate cancer.

ERBB2 CD44

2.38e-052170229894706
Pubmed

The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT).

SGTA AR

2.38e-052170222733359
Pubmed

Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2.

SKP2 AR

2.38e-052170221677876
Pubmed

Expression of androgen receptor in primary breast carcinoma and its relation with clinicopathologic features, estrogen, progesterone, and her-2 receptor status.

ERBB2 AR

2.38e-052170231603099
Pubmed

Protective role of carotenoids in the visual cycle.

ISX BCO2

2.38e-052170229882710
Pubmed

IL-17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44-VCAM-1 interaction.

CD44 VCAM1

2.38e-052170225683512
Pubmed

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor.

ERBB2 ERBIN

2.38e-052170210878805
Pubmed

Differential Expression of HER2 and SKP2 in Benign and Malignant Colorectal Lesions.

ERBB2 SKP2

2.38e-052170232856866
Pubmed

ErbB2 receptor immunoreactivity in prostate cancer: relationship to the androgen receptor, disease severity at diagnosis and disease outcome.

ERBB2 AR

2.38e-052170225215939
Pubmed

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.

EOMES IFNGR1

2.38e-052170227982126
Pubmed

Hyaluronan-CD44 interaction with neural Wiskott-Aldrich syndrome protein (N-WASP) promotes actin polymerization and ErbB2 activation leading to beta-catenin nuclear translocation, transcriptional up-regulation, and cell migration in ovarian tumor cells.

ERBB2 CD44

2.38e-052170217092940
Pubmed

Increased hyaluronan content and stromal cell CD44 associate with HER2 positivity and poor prognosis in human breast cancer.

ERBB2 CD44

2.38e-052170222753277
Pubmed

No association of FOXP2 and PTPRZ1 on 7q31 with autism from the Japanese population.

FOXP2 PTPRZ1

2.38e-052170215998549
Pubmed

Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors.

CD44 VCAM1

2.38e-052170220851866
Pubmed

Reduced androgen receptor expression accelerates the onset of ERBB2 induced breast tumors in female mice.

ERBB2 AR

2.38e-052170223593223
Pubmed

Nested and microcystic variants of urothelial carcinoma displaying immunohistochemical features of basal-like urothelial cells: an immunohistochemical and histopathogenetic study.

KRT5 CD44

2.38e-052170225143125
Pubmed

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

UBE2A UBE2B

2.38e-052170212556476
Pubmed

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

UBE2A UBE2B

2.38e-05217021717990
Pubmed

A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.

KRT83 KRT86

2.38e-052170215744029
Pubmed

Coordinated expression of oestrogen and androgen receptors in HER2-positive breast carcinomas: impact on proliferative activity.

ERBB2 AR

2.38e-052170222039288
Pubmed

Newly identified Gon4l/Udu-interacting proteins implicate novel functions.

GON4L YY1AP1

2.38e-052170232848183
Pubmed

Flat Intraurothelial Neoplasia Exhibiting Diffuse Immunoreactivity for CD44 and Cytokeratin 5 (Urothelial Stem Cell/Basal Cell Markers): A Variant of Intraurothelial Neoplasia Commonly Associated With Muscle-invasive Urothelial Carcinoma.

KRT5 CD44

2.38e-052170226990746
Pubmed

Activation of VCAM-1 and its associated molecule CD44 leads to increased malignant potential of breast cancer cells.

CD44 VCAM1

2.38e-052170224583847
Pubmed

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.

UBE2A UBE2B

2.38e-05217021559696
Pubmed

Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis.

LBP IFNGR1

2.38e-052170211705897
Pubmed

Addition of HER2 and CD44 to 18F-FDG PET-based clinico-radiomic models enhances prediction of neoadjuvant chemoradiotherapy response in esophageal cancer.

ERBB2 CD44

2.38e-052170233151397
Pubmed

A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.

KRT81 KRT86

2.38e-05217029665406
Pubmed

RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.

UBE2A UBE2B

2.38e-052170228806395
Pubmed

Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer.

SKP2 AR

2.38e-052170224347472
Pubmed

Hematopoiesis-dependent expression of CD44 in murine hepatic progenitor cells.

RUNX1 CD44

2.38e-052170219124003
Pubmed

TSC2 loss in lymphangioleiomyomatosis cells correlated with expression of CD44v6, a molecular determinant of metastasis.

TSC2 CD44

2.38e-052170217975002
Pubmed

Novel mode of ligand recognition by the Erbin PDZ domain.

ERBB2 ERBIN

2.38e-052170212444095
Pubmed

An AR-Skp2 pathway for proliferation of androgen-dependent prostate-cancer cells.

SKP2 AR

2.38e-052170218628304
Pubmed

[Expression and clinical significance of p185 and CD44v6 in laryngeal squamous cell carcinoma].

ERBB2 CD44

2.38e-052170216494036
Pubmed

Comprehensive Gene Expression Analyses of Immunohistochemically Defined Subgroups of Muscle-Invasive Urinary Bladder Urothelial Carcinoma.

KRT5 KRT6A

2.38e-052170233435173
Pubmed

Gonadal- and sex-chromosome-dependent sex differences in the circadian system.

AR PER2

2.38e-052170223439698
Pubmed

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

SLC22A11 SLC22A7

2.38e-052170212023506
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT81 KRT83 KRT86

2.44e-0512170310692104
Pubmed

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.

FOXP2 TSC2 EOMES

2.44e-0512170319150975
Pubmed

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.

RNF135 DICER1 DDX41

2.44e-0512170333373584
Pubmed

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.

FOXP2 EOMES ASPM

2.44e-0512170320823249
Pubmed

Structural and functional consequences of NEDD8 phosphorylation.

UBE2C AMBRA1 ANKHD1 NPLOC4 UBE2A

2.46e-0570170534642328
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NOL4 HIVEP1 GATAD2A BICRA GON4L SKP2 TNRC18 ANLN YY1AP1 BAHCC1

2.88e-053981701035016035
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SMAP1 KRT5 VPS13C CCT4 NBEA ERBIN CDKL5 LRIG3 CD44 SLITRK5 RHBDD3 ZFHX3 LRBA PCDH7

3.10e-057771701435844135
InteractionTNRC6A interactions

NCOA6 CNOT11 GATAD2A MED14 ISX GIGYF1 TNRC6C CCNF FAM193A EIF4ENIF1 GIGYF2 AHNAK2

2.89e-0628016212int:TNRC6A
InteractionRRM2 interactions

ERBB2 SKP2 AR NPLOC4 CCNF PCDHGC3 PCDH7 MAP3K2

6.90e-061231628int:RRM2
InteractionKRT25 interactions

KRT5 KRT6A KRT81 KRT83 KRT86

8.43e-06351625int:KRT25
InteractionCTBP2 interactions

NOL4 GATAD2A FOXP2 CWC15 SGTA RNF135 RUNX1 SKP2 AR CCNF CEP68 NOL4L NUFIP2

9.64e-0637016213int:CTBP2
InteractionC2CD4B interactions

CNOT11 MPDZ ERBIN DICER1 PCDH7

2.66e-05441625int:C2CD4B
GeneFamilyKeratins, type II

KRT5 KRT6A KRT81 KRT83 KRT86

6.04e-07271125609
GeneFamilyAtaxins|Trinucleotide repeat containing

FOXP2 TNRC6C TNRC18 GIGYF2

1.60e-05251124775
GeneFamilyPDZ domain containing

SYNPO2 PPP1R9A SYNPO2L MPDZ ERBIN AHNAK2

3.68e-0415211261220
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA LRBA

1.33e-03911221230
GeneFamilyUbiquitin conjugating enzymes E2

UBE2C UBE2A UBE2B

2.08e-03411123102
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ERBB2 SIGLEC5 ITGA3 IFNGR1 CD44 CD180 VCAM1 GP9

3.14e-033941128471
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN

CRTC3 GHDC BICRA TLR7 AR NPLOC4 IKZF5 CEP68 PRDM10 PLEKHA7

6.98e-0815516910M8944
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN

SMAP1 NCOA6 CNOT11 LRRC75B SIDT1 USP43 ANKHD1 AR EOMES

6.39e-062001699M4334
CoexpressionTERAMOTO_OPN_TARGETS_CLUSTER_5

GON4L GIGYF2 YY1AP1

1.44e-0581693MM522
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500

KRT5 KRT6A SYNPO2 MED14 NBEA TNRC6C RUNX1 AR PTPRZ1 ZFP91 TENM1 GIGYF2 ZFHX3 PCDH7 VCAM1

4.50e-0739016615gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 SLC22A11 NCKAP5 LBP SLC22A7 CMIP ARSF TRPM3 SERPINF2 PLEKHA7

2.59e-0918616910b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 LRRC75B SLC22A11 NCKAP5 LBP SLC22A7 ARSF TRPM3 SERPINF2

3.57e-08183169985446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ST6GALNAC1 KRT5 FOXP2 PPP1R9A FHOD3 NBEA LRIG3 PTPRZ1 PLEKHA7

4.71e-08189169984d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KRT81 KRT86 SIGLEC5 LRRC70 EOMES BCO2 ANLN ZFHX3

2.56e-07167169899db8871c62336bd215efb65e969783d2b6003b0
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

KRT5 KRT6A FOXP2 FHOD3 AR PTPRZ1 SLITRK5 PCDH7

3.06e-0717116983965ced4be6db14265a90673502fceee425837ca
ToppCellT_cells-CD56_bright_CD16-_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PLEKHG4 KRT81 KRT86 PPP1R9A USP43 HIF3A BCO2 DPPA4

3.20e-071721698980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT5 KRT6A PCDHGA3 FHOD3 AR PTPRZ1 SLITRK5 PCDH7

3.99e-071771698cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT5 KRT6A PCDHGA3 FHOD3 AR PTPRZ1 SLITRK5 PCDH7

3.99e-071771698ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB2 ATG13 KRT83 PPP1R9A IKZF5 TNRC18 KANK4 PLEKHA7

6.29e-071881698c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellBasal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 KRT5 KRT6A LRIG3 PTPRZ1 SLITRK5 PCDH7 AHNAK2

7.09e-071911698a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCellT_cells-CD56_bright_CD16-_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

LRRC75B KRT81 KRT86 PPP1R9A HIF3A BCO2 DPPA4 ZFHX3

7.67e-071931698826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT5 LRRC75B KCNH8 FHOD3 AR LRIG3 PTPRZ1 SLITRK5

8.29e-0719516986c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT5 KRT6A UBE2C CCNF ANLN RAD54B ASPM PCDH7

9.30e-071981698f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VPS13C GIGYF1 ITGA3 AR PRDM10 TLN1 RHBDD3 VCAM1

9.66e-071991698174f6013af6eafa577f84205a62927f2b367fda3
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

KRT81 KRT83 KRT86 PPP1R9A EOMES BCO2 ZFHX3

3.16e-06164169736e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KRT5 KCNH8 KRT81 KRT86 BEND4 DNAAF3 DPPA4

3.56e-0616716978ddf9da71a7c4ed53588435db826563a24cee616
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

KRT5 POM121L2 TLR7 SLITRK5 SERPINF2 PCDHGC3 AHNAK2

4.16e-061711697779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

KRT5 POM121L2 TLR7 SLITRK5 SERPINF2 PCDHGC3 AHNAK2

4.16e-061711697debbb071d260639b16269c94d172766908325c58
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

KRT5 KCNH8 AR DPPA4 SLITRK5 SERPINF2 PCDHGC3

4.32e-0617216973ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

KRT5 KCNH8 AR DPPA4 SLITRK5 SERPINF2 PCDHGC3

4.32e-061721697a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

KRT81 KRT83 KRT86 PPP1R9A NOL4L BCO2 CD44

4.49e-0617316974a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ECM2 UBE2C ANLN EFCAB8 ASPM ZFHX3 FILIP1L

4.84e-0617516973e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 SLC22A11 NCKAP5 SLC22A7 ARSF TRPM3 SERPINF2

5.22e-0617716972f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 SLC22A11 NCKAP5 SLC22A7 ARSF TRPM3 SERPINF2

6.73e-0618416979434731f651820b05335085582960f08fbf895de
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C RUNX1 CCNF ANLN RAD54B ASPM IMPG2

6.73e-06184169716aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNPO2 FOXP2 CNTLN PAK3 PCDH7 PALLD AHNAK2

6.97e-0618516976712512100ccef456d2e2bd201d0987986c92ac9
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

FOXP2 UBE2C SYNPO2L CNTLN ANLN ASPM SERPINF2

6.97e-061851697912d8efdc37820dbb07736221a98af929e5a7c97
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VPS13C CNTLN CMIP FAM186A TLN1 NUFIP2 ZFHX3

7.22e-06186169723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 SLC22A11 NCKAP5 SLC22A7 ARSF TRPM3 SERPINF2

7.22e-061861697a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 FHOD3 NCKAP5 SLC22A7 CMIP TRPM3 PLEKHA7

7.22e-0618616975784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 FOXP2 ECM2 HIF3A SLITRK5 PAK3 PCDH7

7.75e-061881697ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 PPP1R9A FHOD3 NCKAP5 AR PLEKHA7 VCAM1

8.02e-0618916973b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNPO2 PAK3 ZFHX3 PZP PCDH7 PALLD FILIP1L

8.02e-0618916977ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

KRT5 KRT6A FHOD3 ITGA3 LRIG3 PTPRZ1 PCDH7

8.30e-061901697ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 PPP1R9A USP43 AR CCNF PTPRZ1 ASPM

8.89e-06192169725378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNPO2 PAK3 ZFHX3 PZP PCDH7 PALLD FILIP1L

8.89e-061921697992d08092edbc68c47b945deb8708379738c239a
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

PPP1R9A ROR1 FHOD3 NCKAP5 BCO2 PCDH7 PALLD

8.89e-061921697ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellMS-NK-|MS / Condition, Cell_class and T cell subcluster

LRRC75B KRT81 KRT86 PPP1R9A ROR1 EOMES DPPA4

8.89e-061921697f97f5f8226f5c65ca93072ef35d753231bee2490
ToppCellMS-NK|MS / Condition, Cell_class and T cell subcluster

LRRC75B KRT81 KRT86 PPP1R9A ROR1 EOMES DPPA4

8.89e-061921697f44f5dd30db169fdd16c9d706d17ad44907a17af
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

KRT5 KRT6A FHOD3 ITGA3 LRIG3 PTPRZ1 PCDH7

8.89e-0619216979b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PPP1R9A ROR1 FHOD3 NCKAP5 BCO2 PCDH7 PALLD

9.19e-061931697dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYF5 NOL4 FOXP2 RUNX1 PTPRZ1 SLITRK5 VCAM1

9.19e-0619316971aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PPP1R9A ROR1 FHOD3 NCKAP5 BCO2 PCDH7 PALLD

9.83e-061951697f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT5 KRT6A UBE2C ANLN PTPRZ1 ASPM AHNAK2

1.05e-0519716971d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 PPP1R9A USP43 FHOD3 ITGA3 CD44 PLEKHA7

1.05e-0519716977e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT5 KRT6A FHOD3 NCKAP5 ITGA3 PTPRZ1 PCDH7

1.12e-05199169794a7867e800df352731796de8c24cba133c29622
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNPO2 FOXP2 CNTLN PAK3 PZP PALLD FILIP1L

1.12e-051991697e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ST6GALNAC1 KRT5 KRT6A FHOD3 PER2 PTPRZ1 PCDH7

1.12e-051991697f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellSigmoid-Dendritic_cell|Sigmoid / Region, Cell class and subclass

UBE2C NCKAP5 CNTLN ANLN SERPINF2 PALLD FILIP1L

1.16e-052001697994a49317b806d115c630cd90897a91fc85ff467
ToppCellSigmoid-(5)_Dendritic_cell|Sigmoid / shred on region, Cell_type, and subtype

UBE2C NCKAP5 CNTLN ANLN SERPINF2 PALLD FILIP1L

1.16e-0520016971130328863a4fcfa7dcd7261e9905943057777c5
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT5 SYNPO2 NCKAP5 PTPRZ1 PCDH7 PALLD

2.35e-051501696aa11579a57d671a55e64183d35c1340fda6dec14
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT5 SYNPO2 NCKAP5 PTPRZ1 PCDH7 PALLD

2.63e-05153169682b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FOXP2 KRT86 RAD54B TMEM143 SERPINF2 VCAM1

3.04e-051571696f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCellsevere_COVID-19-NK_CD56bright|severe_COVID-19 / disease group, cell group and cell class (v2)

CLSTN3 KRT81 KRT86 PPP1R9A RDH16 VCAM1

3.15e-051581696c2e8d96fc29aa2388b92b4fd81d2726e1f7a053f
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GALNAC1 FHOD3 HIF3A AR LRIG3 SLITRK5

3.15e-051581696d78e7e52657dc094430291fec07e9c298be9e584
ToppCellICU-SEP-Lymphocyte-T_NK-NK_CD56bright|ICU-SEP / Disease, Lineage and Cell Type

KRT81 KRT86 PPP1R9A BEND4 PAK3 TRAV22

3.15e-05158169653a942cdab4a3c6813dbe11368135a24b8de1880
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 FHOD3 PTPRZ1 PALLD ASPDH AHNAK2

3.38e-0516016968624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 FHOD3 PTPRZ1 PALLD ASPDH AHNAK2

3.38e-0516016969de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT81 KRT86 UBE2C EOMES ANLN ASPM

3.75e-051631696466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Lung / Manually curated celltypes from each tissue

DNHD1 KRT81 KRT86 AMBRA1 AR BCO2

4.29e-051671696dcbcc658082910838c8082d71a64917055086cc4
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

KRT5 TLR7 AR DPPA4 SLITRK5 SERPINF2

4.44e-051681696dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

KRT5 KRT6A TLR7 AR SERPINF2 BAHCC1

4.44e-051681696cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 ROR1 FHOD3 BCO2 PCDH7 PALLD

4.74e-0517016963f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2C SIGLEC5 RUNX1 ANLN CD44 ASPM

4.90e-051711696845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPDZ TLR7 IKZF5 PER2 TRPM3 RHBDD3

4.90e-051711696e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell356C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PPP1R9A ROR1 NCKAP5 PAK3 SERPINF2 VCAM1

4.90e-0517116963d60e7ecf25e4b781ba2387671b2aad247fb75ff
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNPO2 FOXP2 TRPM3 TENM1 ZFHX3 FILIP1L

5.22e-05173169695c723b09254ae7131fe5ba0841472502e83269b
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CRTC3 CASP10 PLEKHG2 ANKHD1 LRBA MAP3K2

5.39e-0517416962274648b80dd74f3c948a779bba3391095964c34
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UBE2C CCNF DNAAF3 ANLN ASPM CD180

5.57e-05175169673f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNPO2 FOXP2 TRPM3 TENM1 ZFHX3 FILIP1L

5.75e-05176169672a2a01618ce836bc843395d5095e9090759b4a6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 NCKAP5 SLC22A7 ARSF TRPM3 SERPINF2

5.75e-0517616961595dbeee336a81e581325d63208ec6262664ee9
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R9A ROR1 CNTLN TRPM3 LRBA PCDH7

5.93e-051771696b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCKAP5 HIF3A AR PTPRZ1 KANK4 ANKFN1

5.93e-051771696fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellASK428-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

NOL4 KRT5 UBE2C TLR7 PTPRZ1 MS4A14

5.93e-05177169666074a288501c136b4e83b883db5f0d8269ee326
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNPO2 FOXP2 TRPM3 TENM1 ZFHX3 FILIP1L

5.93e-0517716964c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|myeloid / Lineage, cell class and subclass

KRT5 KCNH8 SIDT1 AR DPPA4 SLITRK5

6.12e-051781696f75591988bbbeba073b66329a3437cb9b02f7648
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C LBP CCNF ANLN ASPM VCAM1

6.12e-05178169615a99080e9f669572ab6d82934f324e6714846c1
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GALNAC1 FHOD3 AR LRIG3 PTPRZ1 SLITRK5

6.12e-051781696fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C LBP CCNF ANLN ASPM VCAM1

6.12e-051781696200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC75B SLC22A11 NCKAP5 SLC22A7 ARSF TRPM3

6.31e-051791696d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

ST6GALNAC1 KRT5 FHOD3 AR LRIG3 PTPRZ1

6.31e-051791696d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A11 FHOD3 NCKAP5 TRPM3 TENM1 VCAM1

6.51e-051801696358923e4228035a3e90e2957392089219e90dcd7
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KRT81 KRT83 KRT86 PPP1R9A TMEM171 EFCAB8

6.51e-051801696a999a6d219a8e58a8b63802ddf8c95ffaab9cfa0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 FOXP2 BEND4 AR LRIG3 PTPRZ1

6.51e-051801696a407376209d80177bf7fc4200219030c83cb5f14
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 LRIG3 TRPM3 PTPRZ1 ASPM TENM1

6.71e-051811696af92b8b7f455210dab502ef6964f3a0162180759
ToppCell5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT5 KRT6A BCO2 ASPM KNDC1 VCAM1

6.71e-05181169665eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 AR PCDH7 PALLD AHNAK2 FILIP1L

6.71e-051811696ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 ROR1 FHOD3 BCO2 PCDH7 PALLD

6.71e-051811696719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT5 KRT6A BCO2 ASPM KNDC1 VCAM1

6.71e-051811696eaac7d58117eddfff06b25521efc431c1351d592
ToppCellE18.5-samps|World / Age Group, Lineage, Cell class and subclass

FOXP2 DEPP1 NCKAP5 BEND4 HIF3A TMEM171

6.92e-0518216969649f15858d1ede73e068afc59df3ac367b49687
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 ECM2 TLN1 ZFHX3 PALLD FILIP1L

6.92e-051821696ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GALNAC1 FHOD3 NBEA AR PTPRZ1 PCDH7

6.92e-0518216963f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT81 KRT83 KRT86 PPP1R9A TMEM171 CD44

6.92e-0518216966bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 SIGLEC5 TRPM3 PTPRZ1 TENM1 KANK4

6.92e-05182169682ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

KRT5 KCNH8 FHOD3 AR LRIG3 PTPRZ1

7.13e-05183169600a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 LRRC75B LBP SLC22A7 ARSF TRPM3

7.13e-051831696d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 ECM2 TLN1 ZFHX3 PALLD FILIP1L

7.35e-05184169694748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 ECM2 TLN1 ZFHX3 PALLD FILIP1L

7.35e-051841696819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ECM2 UBE2C ANLN RAD54B ASPM ASF1A

7.35e-051841696a0831e850bc0b585296ed350fdd075c1f730308e
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 ROR1 FHOD3 BCO2 PCDH7 PALLD

7.35e-051841696e737f0f14c49b07bbb04a165083ac32210bc5690
DiseaseMONILETHRIX

KRT81 KRT83 KRT86

1.54e-0731593158000
DiseaseBeaded hair

KRT81 KRT83 KRT86

1.54e-0731593cv:C0546966
Diseasemonilethrix (is_implicated_in)

KRT81 KRT83 KRT86

1.54e-0731593DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT83 KRT86

6.12e-0741593C0546966
Diseasesalivary gland cancer (implicated_via_orthology)

GON4L YY1AP1

2.89e-0521592DOID:8850 (implicated_via_orthology)
Diseasehair disease (is_implicated_in)

KRT81 KRT86

2.89e-0521592DOID:421 (is_implicated_in)
Diseasereaction time measurement

GATAD2A FOXP2 ATG13 PPP1R9A UBE2C AMBRA1 NCKAP5 TNRC6C PTPRZ1 NUFIP2 GIGYF2 ZFHX3

2.48e-0465815912EFO_0008393
DiseaseLYMPHOMA, NON-HODGKIN, FAMILIAL

CASP10 RAD54B

2.85e-0451592605027
DiseaseLymphoma, non-Hodgkin, familial

CASP10 RAD54B

2.85e-0451592cv:C4721532
DiseaseNon-Hodgkin lymphoma

CASP10 RAD54B

2.85e-0451592cv:C0024305
DiseaseNeoplasm of the genitourinary tract

ERBB2 AR ZFHX3

2.86e-04241593cv:C0042065
DiseaseMyeloid Leukemia, Chronic

RUNX1 PER2 DDX41

5.06e-04291593C0023473
DiseaseThrombocytopenia

RUNX1 IKZF5 GP9

5.06e-04291593C0040034
DiseaseHelicobacter Infections

IFNGR1 PTPRZ1

5.95e-0471592C0079487
Diseasenon-melanoma skin carcinoma

KRT5 NCOA6 ATG13 NPLOC4 PSORS1C1 EFCAB8 HERC2

6.09e-042651597EFO_0009260
DiseaseAlcohol withdrawal syndrome

MPDZ AR

7.91e-0481592C0236663
Diseaseright ventricular systolic volume measurement

FHOD3 PALLD FILIP1L

8.85e-04351593EFO_0021815
DiseaseMalignant tumor of prostate

AR ZFHX3

1.01e-0391592cv:C0376358
Diseaseinformation processing speed

CRTC3 NCKAP5 IFNGR1 ZFHX3

1.17e-03851594EFO_0004363
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

FOXP2 ZFHX3

1.54e-03111592EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
DiseaseGastric cancer

ERBB2 CASP10

1.54e-03111592cv:C0024623
DiseaseNeoplasm of stomach

ERBB2 CASP10

1.54e-03111592cv:C0038356
Diseasevisual epilepsy (is_implicated_in)

CDKL5 ASPM

1.54e-03111592DOID:11832 (is_implicated_in)
DiseaseGASTRIC CANCER

ERBB2 CASP10

1.54e-03111592613659
Diseasehypertrophic cardiomyopathy

SYNPO2L AMBRA1 FHOD3 NCKAP5

1.57e-03921594EFO_0000538
DiseaseLiver carcinoma

UBE2C SKP2 AR CCNF BCO2 ANLN ASPM PZP VCAM1

1.78e-035071599C2239176
Diseasehair colour measurement, hair morphology measurement

NPLOC4 HERC2

1.84e-03121592EFO_0007821, EFO_0007822
DiseaseEndometrioma

NCOA6 DEPP1 MED14 DICER1 IFNGR1

1.84e-031611595C0269102
DiseaseEndometriosis

NCOA6 DEPP1 MED14 DICER1 IFNGR1

1.84e-031611595C0014175
DiseaseHIV-1 infection

NBEA RUNX1 DNAAF3 PSORS1C1

1.98e-03981594EFO_0000180
DiseaseMalignant neoplasm of breast

KRT5 NCOA6 ERBB2 ROR1 UBR4 UBE2C DEPP1 MED14 AR EOMES PER2 TENM1 LRBA HERC2

2.08e-03107415914C0006142
DiseaseAdenoid Cystic Carcinoma

KRT5 FOXP2 ERBIN ASPM

2.13e-031001594C0010606
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

KCNH8 MPDZ FHOD3

2.22e-03481593EFO_0009268, MONDO_0001627, MONDO_0004975
Diseaseasthma, response to diisocyanate

NOL4 KRT81 KRT86 GIGYF2 HERC2 PCDH7

2.99e-032611596EFO_0006995, MONDO_0004979
DiseaseAutistic Disorder

FOXP2 TAF1C NBEA TSC2 AR MTF1

2.99e-032611596C0004352
Diseaseresponse to tenofovir, creatinine clearance measurement

FHOD3 TRPM3 PZP PCDH7

3.21e-031121594EFO_0007934, EFO_0009279
Diseasesyndromic intellectual disability (implicated_via_orthology)

UBE2A UBE2B

3.29e-03161592DOID:0050888 (implicated_via_orthology)
DiseaseBenign neoplasm of stomach

ERBB2 CASP10

3.72e-03171592C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 CASP10

3.72e-03171592C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 CASP10

3.72e-03171592C0154060
Diseasenon-Hodgkin lymphoma (is_implicated_in)

CASP10 RAD54B

3.72e-03171592DOID:0060060 (is_implicated_in)
Diseasesphingomyelin 14:0 measurement

TRPM3 ZFHX3

3.72e-03171592EFO_0010390
Diseaseprostate cancer (is_implicated_in)

ERBB2 AR CD44 ZFHX3

3.75e-031171594DOID:10283 (is_implicated_in)
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

SERPINF2 VCAM1

4.65e-03191592DOID:1168 (biomarker_via_orthology)
Diseaseosteoporosis (implicated_via_orthology)

AR IFNGR1

4.65e-03191592DOID:11476 (implicated_via_orthology)
DiseaseDiGeorge syndrome (implicated_via_orthology)

ESS2 DICER1

4.65e-03191592DOID:11198 (implicated_via_orthology)
DiseaseHeadache

ATG13 NOL4L NUFIP2

5.03e-03641593HP_0002315
Diseaseserum IgE measurement

SYNPO2 NCKAP5 TLN1

5.03e-03641593EFO_0004579
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

FOXP2 AR

5.14e-03201592DOID:1094 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
QNLAVPAGLPLNETT

ARSF

106

P54793
LQPGQGEQLLASEPS

ARMT1

411

Q9H993
VLDNGDPLNNTTPVT

ERBB2

116

P04626
LPDNDLTTLPASIAN

ERBIN

76

Q96RT1
VPQTNGLLSPQQSEE

EOMES

496

O95936
SGLQQAALLPQELPA

BAHCC1

611

Q9P281
QNPPQLSSLSIDIGA

ATG13

471

O75143
LVPSPLQGLTNQDLQ

ELL3

236

Q9HB65
LTPNTPFLIDNDGNI

CLSTN3

186

Q9BQT9
SLADLPQALDLSQQP

CEP68

156

Q76N32
LQESQGAPLPLPQES

CNTLN

426

Q9NXG0
TSGPNQEQVSPLTLL

SERPINF2

36

P08697
LQILPPSGDSEQLSN

BRDT

756

Q58F21
GEALQPQSLQSPSSI

CDCP2

386

Q5VXM1
SLARPPQDGQQSSDL

DEPP1

161

Q9NTK1
SNPNLQSLLSTDALP

ASF1A

166

Q9Y294
PADQPTEGSKQLLNN

BEND4

376

Q6ZU67
TSPLQDDSINQAPLE

CMIP

191

Q8IY22
PPALENSTALLEGVN

DPPA4

176

Q7L190
ENILSGNPLLNLTGP

CWC15

161

Q9P013
QQVGLDPSPDILGSL

DNHD1

1961

Q96M86
DPSPDILGSLEQLSQ

DNHD1

1966

Q96M86
LLSELPQLSLPSGQQ

DNHD1

2101

Q96M86
FSQELILGPNSETPN

DNHD1

2821

Q96M86
PPEQASSTQQDQGLL

AMBRA1

351

Q9C0C7
GPNPGLILQALTLSN

DICER1

1291

Q9UPY3
NLGLSEIPDTLPNTT

CD180

41

Q99467
QPLSLPSLQNASSLD

DENND1C

616

Q8IV53
NVSLNAPEGDNLSPL

BCO2

416

Q9BYV7
SEPLLQSNLPALVSQ

FAM193A

81

P78312
NEGGPPTENNSLILE

ASPM

201

Q8IZT6
DLESESVNPILSPNQ

ASPM

381

Q8IZT6
LGAPQQLSEASVALP

ISX

146

Q2M1V0
SNPGLNEEITKLNPD

RAD54B

26

Q9Y620
INQLSFPLSSEPIQG

PZP

186

P20742
QIAETLQDPNPSGLQ

ANKRD31

336

Q8N7Z5
LSDNEQPSSPRVNGL

GATAD2A

106

Q86YP4
TNGTPELQNPERLSA

PAK3

491

O75914
NLELQGSVPSAPLLN

LBP

336

P18428
SSEQPGLPLQDLASL

MYF5

216

P13349
PINSSTQGPILEQLQ

GIGYF1

666

O75420
STQKLGSLNNEPALP

NELFA

306

Q9H3P2
SQLVESGNPALEPLT

GGNBP2

101

Q9H3C7
NQSLLTPLNLQIDPT

KRT6A

141

P02538
NNNELETIPNLGPVS

LRIG3

106

Q6UXM1
ININPSDTTVPLLND

HERC2

2866

O95714
GAPLGQSEELQPLSQ

EPN2

211

O95208
RQPLSEASNQQPLSG

ANLN

41

Q9NQW6
VPPSLQLQNLAALGE

ASPDH

51

A6ND91
NQSLLTPLNLQIDPS

KRT5

146

P13647
SLLTPLNLEIDPNAQ

KRT86

86

O43790
LIPTDPAAEGQLLSQ

GPATCH3

66

Q96I76
SSPLQLNLLQLEEAP

PER2

986

O15055
DLINPLNLTLSDPGD

ITGA3

851

P26006
DLAENSAPGTPILQL

PCDH7

316

O60245
LPLLSNPGLINNASS

FOXP2

621

O15409
PPQIGTQNSLELLED

NPLOC4

276

Q8TAT6
PPTSNQDLGEASLQA

GHDC

116

Q8N2G8
INGSTQATNLEPLPS

MAP3K2

121

Q9Y2U5
LGNNVDVASLPQPLL

LRRC75B

246

Q2VPJ9
LENLAGPVSLSTPAQ

LRBA

2071

P50851
SAAPPGASLLLLQQQ

AR

46

P10275
ATLNGLDQPEQTTIP

PRDM10

446

Q9NQV6
ENDIQTGSALLPLSP

PTPRZ1

1521

P23471
IEENNLPGAPILNLS

PCDHGC3

466

Q9UN70
DIPLGPQSNVSLLDQ

DDX41

76

Q9UJV9
LSSNLQPPASLQTGN

NOL4L

346

Q96MY1
STLAGQLSSLPPENQ

IKZF5

256

Q9H5V7
NTSPNSLESPGLEQI

LRRC70

586

Q7Z2Q7
TDLPPQLANLTVANG

MED14

206

O60244
PSEIQQVNNPELGLS

PALLD

581

Q8WX93
DSGNPPLSSNVSLNL

PCDHGA3

536

Q9Y5H0
SQQDLNTPDTRPAGL

NCOA6

926

Q14686
LLLANNSLQSVPPGA

GP9

56

P14770
PLTQDPASITDNLLQ

ESS2

451

Q96DF8
QPLEASNPALEGLTQ

DNAAF3

481

Q8N9W5
SLSEVLAQPQGALAP

DNAAF3

516

Q8N9W5
TTTPGPALEQLQQLE

GIGYF2

716

Q6Y7W6
QDPQALALDTQIPAT

CCNF

666

P41002
LQPTANPNTGLVEDL

CD44

481

P16070
QQPDINLDLSPLTLG

FAM193B

606

Q96PV7
ASPSAPLQDNRTQGL

FILIP1L

1081

Q4L180
SSLPQSDFQLLPAQG

CRTC3

476

Q6UUV7
QEAQLANPEIPLGSA

FHOD3

1016

Q2V2M9
ALEPLPQGIQESLNN

GON4L

1301

Q3T8J9
GVATASLIPNDQLLP

CAPRIN2

571

Q6IMN6
DGNNLIQIPSQLPST

ECM2

401

O94769
QSSNLTANDLPPQGI

MS4A14

346

Q96JA4
TANDLPPQGILSQDT

MS4A14

351

Q96JA4
LSQVPDLQPGSQLFT

EFCAB8

36

A8MWE9
QLSLPQGPEQVLTSS

KANK4

476

Q5T7N3
GALPDAQSPELEQQL

KNDC1

1121

Q76NI1
ALNPEQAPTSLQDSI

CASP10

416

Q92851
TILSSGLPEEPDQNL

FAM102A

201

Q5T9C2
SLTPQQAQELGIPLT

FAM186A

1206

A6NE01
DSILNLQQAPGRTPA

BICRA

1506

Q9NZM4
QTVPNSDSPDLLTLQ

CDKL5

791

O76039
PQALPNTTLGEERQS

SLC22A7

86

Q9Y694
QGLPLPDTIQDLESQ

SLC22A11

516

Q9NSA0
SSQLNLLPTEPGTAD

PKD1L1

966

Q8TDX9
PLSSNQSEPGSIALN

IFNGR1

381

P15260
SLLTPLNLEIDPNAQ

KRT83

91

P78385
NDNPPELIISSLSNS

PCDHB9

341

Q9Y5E1
GSALLNPSLPNQSDV

RUNX1

411

Q01196
NSPNPELLSLVQNLD

SYNPO2L

646

Q9H987
SLQNQRPLSESGPDN

RNF135

151

Q8IUD6
PNGELQPLSENATLT

VCAM1

551

P19320
GLPDLQTKEQQSSPN

TNRC6C

1246

Q9HCJ0
LLQSDENGIPSSPQK

SLC29A2

241

Q14542
PQQTSLGLLDNLAPA

TMCO2

36

Q7Z6W1
PGTSPSQNDLASLIQ

SGTA

261

O43765
DPSTLALLQAVPNQS

NCKAP5

481

O14513
EVPSGLQLEQLPSQS

PLEKHG4

291

Q58EX7
NNAGISLPTAPNELL

RDH16

111

O75452
LNQLGTPQDSPELRQ

STX7

36

O15400
TLPEAQPQNSENGAL

TAF1C

36

Q15572
LPLGANSVLTNNPTI

MTF1

536

Q14872
LNIFELNGLPSETNP

PPP5C

251

P53041
GSLQDPSTPLLNLNE

HIF3A

621

Q9Y2N7
DNLAGPVVLSTPAQL

NBEA

2146

Q8NFP9
NLSGPQQISLFDLPS

PNLDC1

26

Q8NA58
LDQTLPRQGPGQSLS

PLEKHA7

451

Q6IQ23
PALNATPISNTGILE

SIGLEC5

286

O15389
PQQQLLLASLPAGSL

ST6GALNAC1

346

Q9NSC7
IPSTLAENAGLNPIS

CCT4

461

P50991
GSPDPLDLIQQSQTL

TENM1

836

Q9UKZ4
SSLNPDPDSLQLINV

IMPG2

371

Q9BZV3
EQPLNLSDSPLSAQL

NOL4

301

O94818
PSSETDLTQGANPQL

POM121L2

391

Q96KW2
LGQPVQRPASSNLLS

EIF4ENIF1

531

Q9NRA8
LSIQPPSTDLELQAG

AHNAK2

1376

Q8IVF2
SRLPNQNGTVLPSES

ANKHD1

1911

Q8IWZ3
DLNTPNSEGLTPLDI

ANKFN1

166

Q8N957
SPLSSPQQTQLLGEL

CNOT11

336

Q9UKZ1
SSQNPELVIPEGLQA

ZNF837

96

Q96EG3
IQASLLDGPAQEPQS

RHBDD3

301

Q9Y3P4
LPSSGSNQEANIPLL

ROR1

871

Q01973
PDSENIPQELLSNLG

SKP2

46

Q13309
PLLSQLGQPSIFDTQ

TNRC18

141

O15417
SENCLSPSAQLPLGQ

USP43

221

Q70EL4
PNPELLSLLQNSEGK

SYNPO2

706

Q9UMS6
PTLQNESFLLSPNNG

MPDZ

86

O75970
IESQNPLASPTNTLL

NUFIP2

621

Q7Z417
LDQPSLTDPQRLSNE

TMEM143

136

Q96AN5
LNLSIEVPSPSQLDQ

REV1

926

Q9UBZ9
IQSGTFDPVPNLQLL

SLITRK5

496

O94991
DNILSAVPPGLINTS

SAGE2P

311

A6NJ88
NTSPEELGPLANQLT

TLN1

1876

Q9Y490
LSKNTAPDNGPILLQ

TBL3

456

Q12788
PLDNSVNILGLGEPS

TRPM3

1441

Q9HCF6
PSEATNETGPLQQLI

SIDT1

131

Q9NXL6
SQPSLGGESLNLPNT

ZNF410

401

Q86VK4
TQTPALQGPQLLNTD

PSORS1C1

16

Q9UIG5
LQGPQLLNTDPSSEE

PSORS1C1

21

Q9UIG5
LTSIQSLLDEPNPNS

UBE2A

106

P49459
SSPGLLSLSLNQQPA

THOC6

296

Q86W42
QTLNAKNGLTSPLEP

USP29

246

Q9HBJ7
NGNTTVPPLNDDLDI

SMAP1

231

Q8IYB5
ILLENLGEASSQPSP

VPS13C

1881

Q709C8
VAESPGTNSLLPNEN

TMEM171

236

Q8WVE6
LPPSLQLLSLEANNI

TLR7

146

Q9NYK1
LLQVSEPVNPELSAG

nan

506

Q3C1V9
QALEPLPQGIQESLN

YY1AP1

756

Q9H869
SQGQQFPALLTDPSL

ZNF236

1591

Q9UL36
NAPLSLSQELPDTQV

PLEKHG2

1126

Q9H7P9
ESLTQPSDGQGLPLL

ZFP91

481

Q96JP5
ITNQLGLTFQLPLPE

ZNF766

106

Q5HY98
LETAENVNNGNPSPL

UBR4

2776

Q5T4S7
QSPPDLILQEGANST

TRAV22

26

A0A0B4J277
GLQNLSTPGLQSLPS

HIVEP1

2476

P15822
LTSIQSLLDEPNPNS

UBE2B

106

P63146
NQPNLDTQSGPESLL

ZMYM3

756

Q14202
QNPTLGETPENSNLE

ZNF449

291

Q6P9G9
GDESNKPILLPNESQ

TSC2

1511

P49815
QSLLGEPNIDSPLNT

UBE2C

136

O00762
NPLLASQLLSGAIPQ

ZFHX3

2581

Q15911
LQLSTLNNAGPPDLS

KCNH8

796

Q96L42
SLLTPLNLEIDPNAQ

KRT81

86

Q14533
IPSPQSQLLEDAEAN

PPP1R9A

336

Q9ULJ8