Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004354
GeneOntologyMolecularFunction	phosphoprotein phosphatase activity	ACP2 TPTE2 PTPRT PTPN13 PTPRK PTPRM PTPRQ TNS1	7.33e-05	189	145	8	GO:0004721
GeneOntologyMolecularFunction	gamma-catenin binding	APC PTPRT PTPRK	7.86e-05	12	145	3	GO:0045295
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	TPTE2 PTPRT PTPN13 PTPRK PTPRM PTPRQ	1.06e-04	103	145	6	GO:0004725
GeneOntologyMolecularFunction	EGF-domain serine glucosyltransferase activity	POGLUT3 POGLUT1	1.56e-04	3	145	2	GO:0140561
GeneOntologyMolecularFunction	EGF-domain serine xylosyltransferase activity	POGLUT3 POGLUT1	1.56e-04	3	145	2	GO:0140562
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRT PTPRK PTPRM	2.37e-04	17	145	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRT PTPRK PTPRM	2.37e-04	17	145	3	GO:0019198
GeneOntologyMolecularFunction	phosphatase activity	ACP7 ACP2 TPTE2 PTPRT PTPN13 PTPRK PTPRM PTPRQ TNS1	2.55e-04	287	145	9	GO:0016791
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	1.07e-03	7	145	2	GO:0070728
Domain	KRAB	ZNF573 ZNF560 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	3.86e-06	358	143	13	PS50805
Domain	KRAB	ZNF573 ZNF560 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	5.36e-06	369	143	13	SM00349
Domain	KRAB	ZNF573 ZNF560 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	5.51e-06	370	143	13	IPR001909
Domain	-	TPTE2 PTPRT PTPN13 PTPRK PTPRM STYXL1 TNS1	6.78e-06	92	143	7	3.90.190.10
Domain	Prot-tyrosine_phosphatase-like	TPTE2 PTPRT PTPN13 PTPRK PTPRM STYXL1 TNS1	1.10e-05	99	143	7	IPR029021
Domain	KRAB	ZNF573 ZNF560 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	2.05e-05	358	143	12	PF01352
Domain	zf-C2H2_6	ZNF573 ZNF560 ZFP28 ZNF225 ZNF227 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	3.07e-05	314	143	11	PF13912
Domain	LisH	TBL1Y TBL1XR1 TBL1X	3.57e-05	9	143	3	PF08513
Domain	TYR_PHOSPHATASE_dom	TPTE2 PTPRT PTPN13 PTPRK PTPRM STYXL1	5.50e-05	87	143	6	IPR000387
Domain	TYR_PHOSPHATASE_2	TPTE2 PTPRT PTPN13 PTPRK PTPRM STYXL1	5.50e-05	87	143	6	PS50056
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	5.82e-05	2	143	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	5.82e-05	2	143	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	5.82e-05	2	143	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	5.82e-05	2	143	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	5.82e-05	2	143	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	5.82e-05	2	143	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	5.82e-05	2	143	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	5.82e-05	2	143	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	5.82e-05	2	143	2	IPR033524
Domain	PTPc_motif	PTPRT PTPN13 PTPRK PTPRM TNS1	8.81e-05	59	143	5	SM00404
Domain	Tyr_Pase_cat	PTPRT PTPN13 PTPRK PTPRM TNS1	8.81e-05	59	143	5	IPR003595
Domain	FN3	COL6A3 MYOM1 PTPRT PTPRK PTPRM FLRT3 USH2A CNTN2	9.07e-05	185	143	8	SM00060
Domain	FN3	COL6A3 MYOM1 PTPRT PTPRK PTPRM FLRT3 USH2A CNTN2	1.50e-04	199	143	8	PS50853
Domain	PTPc	PTPRT PTPN13 PTPRK PTPRM	1.60e-04	36	143	4	SM00194
Domain	LipoPS_modifying	POGLUT3 POGLUT1	1.74e-04	3	143	2	IPR006598
Domain	Glyco_transf_90	POGLUT3 POGLUT1	1.74e-04	3	143	2	PF05686
Domain	CAP10	POGLUT3 POGLUT1	1.74e-04	3	143	2	SM00672
Domain	FN3_dom	COL6A3 MYOM1 PTPRT PTPRK PTPRM FLRT3 USH2A CNTN2	2.10e-04	209	143	8	IPR003961
Domain	TYR_PHOSPHATASE_PTP	PTPRT PTPN13 PTPRK PTPRM	2.20e-04	39	143	4	PS50055
Domain	-	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	2.26e-04	679	143	15	3.30.160.60
Domain	MAM_1	PTPRT PTPRK PTPRM	2.29e-04	16	143	3	PS00740
Domain	fn3	MYOM1 PTPRT PTPRK PTPRM FLRT3 USH2A CNTN2	2.53e-04	162	143	7	PF00041
Domain	PTPase_domain	PTPRT PTPN13 PTPRK PTPRM	2.68e-04	41	143	4	IPR000242
Domain	Y_phosphatase	PTPRT PTPN13 PTPRK PTPRM	2.68e-04	41	143	4	PF00102
Domain	P-loop_NTPase	NDST1 MYH4 MYO9A DDX60 CHD7 GAL3ST2 TRIP13 IQGAP1 DDX10 RAB10 LRGUK DDX18 CHD6 SEPTIN7 DSEL RAB37 DNAH8	2.69e-04	848	143	17	IPR027417
Domain	MAM	PTPRT PTPRK PTPRM	2.76e-04	17	143	3	SM00137
Domain	zf-C2H2	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	2.81e-04	693	143	15	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	2.85e-04	694	143	15	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 SUZ12 ZNF30 ZFP69B ZNF417	2.97e-04	775	143	16	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 SUZ12 ZNF30 ZFP69B ZNF417	3.06e-04	777	143	16	PS00028
Domain	MAM	PTPRT PTPRK PTPRM	3.30e-04	18	143	3	PF00629
Domain	MAM_dom	PTPRT PTPRK PTPRM	3.30e-04	18	143	3	IPR000998
Domain	MAM_2	PTPRT PTPRK PTPRM	3.30e-04	18	143	3	PS50060
Domain	PP2A_PR55_CS	PPP2R2A PPP2R2B	3.46e-04	4	143	2	IPR018067
Domain	DUF4217	DDX10 DDX18	3.46e-04	4	143	2	PF13959
Domain	TRPM_tetra	TRPM6 TRPM7	3.46e-04	4	143	2	PF16519
Domain	PP2A_PR55	PPP2R2A PPP2R2B	3.46e-04	4	143	2	IPR000009
Domain	TRPM_tetra	TRPM6 TRPM7	3.46e-04	4	143	2	IPR032415
Domain	DUF4217	DDX10 DDX18	3.46e-04	4	143	2	SM01178
Domain	DUF4217	DDX10 DDX18	3.46e-04	4	143	2	IPR025313
Domain	PR55_2	PPP2R2A PPP2R2B	3.46e-04	4	143	2	PS01025
Domain	PR55_1	PPP2R2A PPP2R2B	3.46e-04	4	143	2	PS01024
Domain	Znf_C2H2-like	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 SUZ12 ZNF30 ZFP69B ZNF417	3.99e-04	796	143	16	IPR015880
Domain	ZnF_C2H2	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 SUZ12 ZNF30 ZFP69B ZNF417	4.70e-04	808	143	16	SM00355
Domain	TYR_PHOSPHATASE_1	TPTE2 PTPRT PTPN13 PTPRK PTPRM	5.19e-04	86	143	5	PS00383
Domain	Alpha_kinase	TRPM6 TRPM7	8.56e-04	6	143	2	PF02816
Domain	BRK	CHD7 CHD6	8.56e-04	6	143	2	SM00592
Domain	MHCK_EF2_kinase	TRPM6 TRPM7	8.56e-04	6	143	2	IPR004166
Domain	BRK_domain	CHD7 CHD6	8.56e-04	6	143	2	IPR006576
Domain	ALPHA_KINASE	TRPM6 TRPM7	8.56e-04	6	143	2	PS51158
Domain	Alpha_kinase	TRPM6 TRPM7	8.56e-04	6	143	2	SM00811
Domain	BRK	CHD7 CHD6	8.56e-04	6	143	2	PF07533
Domain	Lipome_HGMIC_fus_partner-like	LHFPL3 LHFPL5	1.19e-03	7	143	2	IPR019372
Domain	L_HMGIC_fpl	LHFPL3 LHFPL5	1.19e-03	7	143	2	PF10242
Domain	LisH	TBL1Y TBL1XR1 TBL1X	1.25e-03	28	143	3	IPR006594
Domain	LisH	TBL1Y TBL1XR1 TBL1X	1.25e-03	28	143	3	SM00667
Domain	LISH	TBL1Y TBL1XR1 TBL1X	1.25e-03	28	143	3	PS50896
Domain	Znf_C2H2	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 ZNF30 ZFP69B ZNF417	1.31e-03	805	143	15	IPR007087
Domain	Helicase_C	DDX60 CHD7 DDX10 DDX18 CHD6	1.39e-03	107	143	5	PF00271
Domain	HELICc	DDX60 CHD7 DDX10 DDX18 CHD6	1.39e-03	107	143	5	SM00490
Domain	Helicase_C	DDX60 CHD7 DDX10 DDX18 CHD6	1.45e-03	108	143	5	IPR001650
Domain	HELICASE_CTER	DDX60 CHD7 DDX10 DDX18 CHD6	1.51e-03	109	143	5	PS51194
Domain	HELICASE_ATP_BIND_1	DDX60 CHD7 DDX10 DDX18 CHD6	1.51e-03	109	143	5	PS51192
Domain	DEXDc	DDX60 CHD7 DDX10 DDX18 CHD6	1.51e-03	109	143	5	SM00487
Domain	Helicase_ATP-bd	DDX60 CHD7 DDX10 DDX18 CHD6	1.58e-03	110	143	5	IPR014001
Domain	PTEN_C2	TPTE2 TNS1	1.58e-03	8	143	2	PF10409
Domain	PTEN_C2	TPTE2 TNS1	1.58e-03	8	143	2	SM01326
Domain	C2_TENSIN	TPTE2 TNS1	1.58e-03	8	143	2	PS51182
Domain	Tensin_lipid_phosphatase_dom	TPTE2 TNS1	1.58e-03	8	143	2	IPR029023
Domain	Tensin_C2-dom	TPTE2 TNS1	1.58e-03	8	143	2	IPR014020
Domain	PPASE_TENSIN	TPTE2 TNS1	2.02e-03	9	143	2	PS51181
Domain	Tyr_Pase_AS	TPTE2 PTPRT PTPRK PTPRM	2.38e-03	73	143	4	IPR016130
Domain	Rho_GTPase_activation_prot	MYO9A CHN1 FAM13B IQGAP1	4.67e-03	88	143	4	IPR008936
Domain	-	NDST1 DDX60 CHD7 TRIP13 DDX10 RAB10 LRGUK DDX18 CHD6 SEPTIN7 DSEL RAB37 DNAH8	4.84e-03	746	143	13	3.40.50.300
Domain	Septin	TMEM250 SEPTIN7	4.99e-03	14	143	2	IPR016491
Domain	WW	NEDD4L IQGAP1 PIN1	5.57e-03	47	143	3	PF00397
Domain	WW	NEDD4L IQGAP1 PIN1	5.91e-03	48	143	3	SM00456
Domain	WW_DOMAIN_1	NEDD4L IQGAP1 PIN1	7.00e-03	51	143	3	PS01159
Domain	WW_DOMAIN_2	NEDD4L IQGAP1 PIN1	7.00e-03	51	143	3	PS50020
Domain	WW_dom	NEDD4L IQGAP1 PIN1	7.39e-03	52	143	3	IPR001202
Pubmed	Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.	TBL1Y TBL1XR1 TBL1X	7.20e-07	5	146	3	21459324
Pubmed	Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.	TBL1Y TBL1XR1 TBL1X	1.44e-06	6	146	3	28348241
Pubmed	The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.	TBL1Y TBL1XR1 TBL1X	2.51e-06	7	146	3	15695367
Pubmed	Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.	TBL1Y TBL1XR1 TBL1X	2.51e-06	7	146	3	27646874
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	GGNBP2 MUC16 ZDBF2 CHD7 ZNF227 CSMD2 RAB10 PPP2R2B KMT2D IPO9 ADAMTS6 CHD6 SMCR8	3.23e-06	638	146	13	31182584
Pubmed	A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.	TBL1Y TBL1XR1 TBL1X	4.00e-06	8	146	3	16127449
Pubmed	Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.	TBL1Y TBL1XR1 TBL1X	4.00e-06	8	146	3	23770565
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NDST1 TRPM7 SYNM ADAM23 ZBTB4 APC ZNF227 STAT5B IQGAP1 ZNF34 PTPN13 PTPRK DDX18 GLUD1 USP32 CHD6 SEPTIN7 RSBN1L	7.97e-06	1285	146	18	35914814
Pubmed	A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.	TBL1Y TBL1XR1 TBL1X	8.51e-06	10	146	3	14980219
Pubmed	Strain-specific modifier genes governing craniofacial phenotypes.	B3GALT6 IPO9 DAAM1	1.55e-05	12	146	3	22371338
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CPAMD8 NEDD4L ATG7 CACNA2D2 MYO9A TBL1XR1 TRIP13 ADCY3 STAT5B RAB10 PPP2R2A PTPN13 POGLUT1 ZNF587 STYXL1 OS9 CHD6 DAAM1 TBL1X	1.62e-05	1489	146	19	28611215
Pubmed	Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7.	TRPM6 TRPM7	1.75e-05	2	146	2	16636202
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	1.75e-05	2	146	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.75e-05	2	146	2	28621566
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.75e-05	2	146	2	32078638
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	1.75e-05	2	146	2	23595828
Pubmed	Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.	PPP2R2A PPP2R2B	1.75e-05	2	146	2	24244166
Pubmed	TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.	TRPM6 TRPM7	1.75e-05	2	146	2	24858416
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	1.75e-05	2	146	2	21621574
Pubmed	TBL1X: At the crossroads of transcriptional and posttranscriptional regulation.	TBL1XR1 TBL1X	1.75e-05	2	146	2	36206873
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.75e-05	2	146	2	28911206
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	1.75e-05	2	146	2	22875990
Pubmed	Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth.	ATG7 APC	1.75e-05	2	146	2	26214133
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	1.75e-05	2	146	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.75e-05	2	146	2	15044002
Pubmed	Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.	TRPM6 TRPM7	1.75e-05	2	146	2	19149903
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	1.75e-05	2	146	2	22138648
Pubmed	Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.	TRPM6 TRPM7	1.75e-05	2	146	2	18365021
Pubmed	Autophagy in the intestinal epithelium is not involved in the pathogenesis of intestinal tumors.	ATG7 APC	1.75e-05	2	146	2	22546555
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	1.75e-05	2	146	2	34220417
Pubmed	Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.	TRPM6 TRPM7	1.75e-05	2	146	2	14976260
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	1.75e-05	2	146	2	26241911
Pubmed	The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor.	APC PTPN13	1.75e-05	2	146	2	24928580
Pubmed	CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.	CHD7 KMT2D	1.75e-05	2	146	2	28475860
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	1.75e-05	2	146	2	21446915
Pubmed	Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.	TRPM6 TRPM7	1.75e-05	2	146	2	21602712
Pubmed	X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.	TBL1Y TBL1X	1.75e-05	2	146	2	10330347
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	1.75e-05	2	146	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	1.75e-05	2	146	2	24593767
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	1.75e-05	2	146	2	37154294
Pubmed	The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1.	IQGAP1 PTPRM	1.75e-05	2	146	2	16380380
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	1.75e-05	2	146	2	22924626
Pubmed	Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.	TRPM6 TRPM7	1.75e-05	2	146	2	25692682
Pubmed	The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.	TRPM6 TRPM7	1.75e-05	2	146	2	24385424
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	1.75e-05	2	146	2	11032875
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	1.75e-05	2	146	2	29943084
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	1.75e-05	2	146	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	1.75e-05	2	146	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	1.75e-05	2	146	2	27422263
Pubmed	The channel kinases TRPM6 and TRPM7 are functionally nonredundant.	TRPM6 TRPM7	1.75e-05	2	146	2	16150690
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.75e-05	2	146	2	15750346
Pubmed	TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP.	TRPM6 TRPM7	1.75e-05	2	146	2	28821869
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	1.75e-05	2	146	2	1711373
Pubmed	Involvement of protein phosphatase 2A in the maintenance of E-cadherin-mediated cell-cell adhesion through recruitment of IQGAP1.	IQGAP1 PPP2R2B	1.75e-05	2	146	2	16245300
Pubmed	Recent developments in intestinal magnesium absorption.	TRPM6 TRPM7	1.75e-05	2	146	2	18301276
Pubmed	The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.	TRPM6 TRPM7	1.75e-05	2	146	2	18675813
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	1.75e-05	2	146	2	20529287
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	1.75e-05	2	146	2	25124006
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	1.75e-05	2	146	2	23673664
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	1.75e-05	2	146	2	39052831
Pubmed	Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.	TRPM6 TRPM7	1.75e-05	2	146	2	28220887
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	1.75e-05	2	146	2	24442550
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	1.75e-05	2	146	2	27137930
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	1.75e-05	2	146	2	26440896
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	1.75e-05	2	146	2	12742085
Pubmed	Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.	TRPM6 TRPM7	1.75e-05	2	146	2	18192217
Pubmed	Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.	PTPRK PTPRM	1.75e-05	2	146	2	36436563
Pubmed	SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth.	TBL1XR1 TBL1X	1.75e-05	2	146	2	27129164
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	1.75e-05	2	146	2	18688271
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	1.75e-05	2	146	2	22658952
Pubmed	Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin.	TRPM6 TRPM7	1.75e-05	2	146	2	26563869
Pubmed	The Different Roles of The Channel-Kinases TRPM6 and TRPM7.	TRPM6 TRPM7	1.75e-05	2	146	2	26179995
Pubmed	Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.	TRPM6 TRPM7	1.75e-05	2	146	2	16075242
Pubmed	The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells.	LHFPL3 LHFPL5	1.75e-05	2	146	2	36917610
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	1.75e-05	2	146	2	38124277
Pubmed	Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart.	TRPM6 TRPM7	1.75e-05	2	146	2	34326388
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	1.75e-05	2	146	2	19015267
Pubmed	TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon.	TRPM6 TRPM7	1.75e-05	2	146	2	29912157
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	1.75e-05	2	146	2	19448744
Pubmed	Magnesium and its transporters in cancer: a novel paradigm in tumour development.	TRPM6 TRPM7	1.75e-05	2	146	2	22671428
Pubmed	Homophilic interactions mediated by receptor tyrosine phosphatases mu and kappa. A critical role for the novel extracellular MAM domain.	PTPRK PTPRM	1.75e-05	2	146	2	7782276
Pubmed	Transducin β-like 1, X-linked and nuclear receptor co-repressor cooperatively augment the ligand-independent stimulation of TRH and TSHβ gene promoters by thyroid hormone receptors.	TBL1Y TBL1X	1.75e-05	2	146	2	29794369
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	1.75e-05	2	146	2	11950837
Pubmed	Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.	TRPM6 TRPM7	1.75e-05	2	146	2	20875900
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CPAMD8 ZNF573 HYOU1 NEDD4L ATG7 TRPM7 EXPH5 POLD2 APC ZNF34 PPP2R2B POGLUT1 ARL14EP DAAM1 SEPTIN7 ZNF417 SMCR8	3.23e-05	1293	146	17	15342556
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY3 PTPRQ USH2A	3.90e-05	16	146	3	17567809
Pubmed	Candidate genes and their regulatory elements: alcohol preference and tolerance.	HYOU1 TBL1Y TBL1X	4.72e-05	17	146	3	16783646
Pubmed	Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus.	EMX2 CNTN2	5.24e-05	3	146	2	12209834
Pubmed	The structure of apo human glutamate dehydrogenase details subunit communication and allostery.	GLUD1 GLUD2	5.24e-05	3	146	2	12054821
Pubmed	Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC.	APC PIN1	5.24e-05	3	146	2	11533658
Pubmed	Tbl1 promotes Wnt-β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells.	TBL1Y TBL1X	5.24e-05	3	146	2	38639717
Pubmed	Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling.	POGLUT3 POGLUT1	5.24e-05	3	146	2	30127001
Pubmed	Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.	GLUD1 GLUD2	5.24e-05	3	146	2	31704028
Pubmed	Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).	CHD7 KMT2D	5.24e-05	3	146	2	28007623
Pubmed	Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation.	TBL1Y TBL1X	5.24e-05	3	146	2	21189284
Pubmed	Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform.	PPP2R2A PPP2R2B	5.24e-05	3	146	2	1849734
Pubmed	N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.	TRPM6 TRPM7	5.24e-05	3	146	2	25277194
Pubmed	Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase.	POGLUT3 POGLUT1	5.24e-05	3	146	2	21949356
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD7 CHD6	5.24e-05	3	146	2	28533432
Pubmed	Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.	GLUD1 GLUD2	5.24e-05	3	146	2	29784783
GeneFamily	Fibronectin type III domain containing	MYOM1 PTPRT PTPRK PTPRM PTPRQ FLRT3 USH2A CNTN2	6.88e-06	160	112	8	555
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRT PTPRK PTPRM PTPRQ	7.70e-06	21	112	4	813
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF573 ZFAT ZNF560 ZBTB4 ZIM2 ZFP28 ZNF225 ZNF227 ZNF34 ZNF676 ZNF587 ZNF737 SUZ12 ZNF30 ZFP69B ZNF417	8.81e-06	718	112	16	28
GeneFamily	Glycosyltransferase family 90	POGLUT3 POGLUT1	1.14e-04	3	112	2	443
GeneFamily	C2 tensin-type domain containing\|PTEN protein phosphatases\|Phosphoinositide phosphatases	TPTE2 TNS1	3.76e-04	5	112	2	902
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TPTE2 TNS1	1.04e-03	8	112	2	837
GeneFamily	DEAD-box helicases	DDX60 DDX10 DDX18	2.23e-03	42	112	3	499
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R2A PPP2R2B	3.79e-03	15	112	2	696
Coexpression	GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN	LUZP4 SYNM CHN1 ZNF34 PTPN13 POGLUT1 TNS1 MVB12B	1.51e-05	198	145	8	M5545
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN	NDST1 GGNBP2 ZNF573 RIOX1 ADCY3 KMT2D GLCE CDC23	1.57e-05	199	145	8	M7711
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM250 NDST1 ACP2 RIOX1 CHN1 GLUD1 BAHCC1	8.14e-07	156	145	7	abea3c183d32062b009a79a2bdf861021989c7ef
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	POGLUT3 MYOM1 MUC16 GAL3ST2 ZNF34 GTF2E1 DGAT2	1.01e-06	161	145	7	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	severe_influenza-CD8+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	MYOM1 CENPS ZDBF2 CHD7 ZNF225 CHN1 ADAMTS6	1.01e-06	161	145	7	82196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBL1Y CSMD2 PTPRT CEMIP PTPRM FLRT3 DMP1	2.45e-06	184	145	7	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LHFPL3 BRINP1 CSMD2 PTPRT CEMIP PTPRK EMX2	3.24e-06	192	145	7	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	CACNA2D2 APC BRINP1 PTPRT THY1 PTPRM SEPTIN7	3.47e-06	194	145	7	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	CACNA2D2 APC BRINP1 PTPRT THY1 PTPRM SEPTIN7	3.47e-06	194	145	7	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L CACNA2D2 MYO9A EXPH5 PTPN13 PTPRK PTPRM	3.59e-06	195	145	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L CACNA2D2 EXPH5 LHFPL3 PTPN13 PTPRK PTPRM	4.11e-06	199	145	7	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17\|blood / Manually curated celltypes from each tissue	ADAM23 PBX4 CHN1 PTPN13 PTPRM ZNF587	1.28e-05	157	145	6	c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCell	severe_influenza-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	MYOM1 CENPS ZDBF2 ZNF225 CHN1 ADAMTS6	1.42e-05	160	145	6	a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HYOU1 MYOM1 ZFP28 ADCY3 TMTC1 CNTN2	1.53e-05	162	145	6	502ed67f6a572f10ac6e22948a1747d8214eb974
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HYOU1 MYOM1 ZFP28 ADCY3 TMTC1 CNTN2	1.53e-05	162	145	6	82e782096f89cd03d1fdf599ba727d6f23e35e2d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HYOU1 MYOM1 ZFP28 ADCY3 TMTC1 CNTN2	1.53e-05	162	145	6	6bed33b17b59812646dc6a29c1d87413bad86c11
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHN1 THY1 PTPRK DAAM1 DMP1 RAB37	2.85e-05	181	145	6	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHN1 THY1 PTPRK DAAM1 DMP1 RAB37	2.85e-05	181	145	6	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GJD2 CACNA2D2 APC PTPRM LHFPL5 CHD6	2.94e-05	182	145	6	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 MYOM1 TLX1 THY1 SEPTIN7 EMX2	3.23e-05	185	145	6	35d39a1d04c871edcfb749653538dc5fd0054281
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	COL6A3 SYNM CHN1 ADCY3 ZNF676 TNS1	3.43e-05	187	145	6	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	NEDD4L CACNA2D2 EXPH5 LHFPL3 PTPN13 PTPRK	3.53e-05	188	145	6	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM23 BRINP1 CHN1 AGBL4 PTPRK SEC14L5	3.64e-05	189	145	6	a75226616340045b581d08429d2e123e041dee55
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 NEDD4L PTPN13 PTPRK PTPRM PTPRQ	3.75e-05	190	145	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM23 BRINP1 CHN1 AGBL4 PTPRK SEC14L5	3.75e-05	190	145	6	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM23 BRINP1 CHN1 AGBL4 PTPRK SEC14L5	3.75e-05	190	145	6	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 LHFPL3 PTPRT STAT5B TMTC1 PTPRM	3.86e-05	191	145	6	de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 LHFPL3 PTPRT STAT5B TMTC1 PTPRM	3.86e-05	191	145	6	9c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 LHFPL3 PTPRT STAT5B TMTC1 PTPRM	4.09e-05	193	145	6	2c15186d15545804cc262da9137ab825609d4b2c
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	EXOC5 PTPRK USP32 SUZ12 ZFP69B SMCR8	4.09e-05	193	145	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	remission-B_intermediate\|World / disease stage, cell group and cell class	CHD7 CR2 PTPRK ADAMTS6 TMED8 AIM2	4.21e-05	194	145	6	78556b60c84c7bbffa1c8bf8684b3c427512da44
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L CACNA2D2 MYO9A PTPN13 PTPRK PTPRM	4.21e-05	194	145	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP1 CSMD2 CHN1 PTPRT CEMIP PTPRK	4.33e-05	195	145	6	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	NEDD4L CACNA2D2 EXPH5 PTPN13 PTPRK FLRT3	4.33e-05	195	145	6	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MYO9A LHFPL3 USP43 AGBL4 PTPN13	4.58e-05	197	145	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL6A3 CHN1 ADCY3 THY1 SEPTIN7 TNS1	4.58e-05	197	145	6	44cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL6A3 CHN1 ADCY3 THY1 SEPTIN7 TNS1	4.71e-05	198	145	6	76d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM6 PTPRT CEMIP PTPN13 FLRT3 TNS1	4.85e-05	199	145	6	94a7867e800df352731796de8c24cba133c29622
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	CHD7 CR2 PTPRK ADAMTS6 AIM2 DNAH8	4.85e-05	199	145	6	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L CACNA2D2 MYO9A EXPH5 PTPN13 PTPRK	4.85e-05	199	145	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	ASK428-Epithelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	NEDD4L CACNA2D2 EXPH5 PTPN13 FLRT3 TNS1	4.85e-05	199	145	6	ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	GJD2 APCDD1 LHFPL3 PTPRT PTPRM AVIL	4.98e-05	200	145	6	a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCell	mild-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD7 CR2 PTPRK ADAMTS6 AIM2 DNAH8	4.98e-05	200	145	6	fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD7 CR2 PTPRK ADAMTS6 AIM2 DNAH8	4.98e-05	200	145	6	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	USP43 BRINP1 CHN1 AGBL4 PTPRK SEC14L5	4.98e-05	200	145	6	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CACNA2D2 SYNM CENPS ADAMTS6 LHFPL5	5.79e-05	126	145	5	3a14d4eb8803827946c36faeeb7ae2913418d421
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CACNA2D2 CR2 CEMIP ADAMTS6 RAB37	8.03e-05	135	145	5	54b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJD2 LRGUK LHFPL5 USH2A DCAF12	9.22e-05	139	145	5	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	PND07-28-samps-Mesenchymal-Pericyte-pericyte_F\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MBOAT1 USP43 RIOX1 GTF2E1 RAB37	1.32e-04	150	145	5	2d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCell	PND07-28-samps-Mesenchymal-Pericyte\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MBOAT1 USP43 RIOX1 GTF2E1 RAB37	1.32e-04	150	145	5	5b111ec11a642d63fafa7e1422e36f81a2776531
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	USP43 MUC16 PBX4 PTPRT AGBL4	1.58e-04	156	145	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MBOAT1 CHN1 ADAMTS6 AVIL CDC23	1.68e-04	158	145	5	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 NEDD4L MBOAT1 TPTE2 USP43	1.68e-04	158	145	5	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZNF34 PPP2R2B CHD6 MVB12B	1.78e-04	160	145	5	50d4f867d021abcfeb49e6812bcfd5bb57466a31
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZNF34 PPP2R2B CHD6 MVB12B	1.78e-04	160	145	5	0f15f895f11dcabb73df79b26bfc4947f38435a7
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZNF34 PPP2R2B CHD6 MVB12B	1.78e-04	160	145	5	7d004bfe42707605b3851cb2319126acda4d4802
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GJD2 CACNA2D2 APC PTPRM CHD6	1.83e-04	161	145	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	normal-na-Lymphocytic_B-B_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NEDD4L MUC16 CR2 CEMIP AIM2	1.89e-04	162	145	5	ae292318d339305932457bb0e91430594f7a3dfa
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM250 NDST1 ACADM TNS1 BAHCC1	2.06e-04	165	145	5	436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM250 NDST1 ACADM TNS1 BAHCC1	2.06e-04	165	145	5	242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	TRPM6 NDST1 EXPH5 PBX4 FLRT3	2.06e-04	165	145	5	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	Control\|World / group, cell type (main and fine annotations)	NEDD4L CACNA2D2 EXPH5 LHFPL3 PTPRK	2.24e-04	168	145	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	ZFAT MYO9A ARL14EP TNS1 BAHCC1	2.24e-04	168	145	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ATP8B4 LHFPL3 AVIL RAB37	2.30e-04	169	145	5	630d921aa8fb5681d06a4e09b833855c374be484
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ATP8B4 LHFPL3 AVIL RAB37	2.30e-04	169	145	5	468284d4a3a0557aed04eadb1aba2317babc6904
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ATP8B4 LHFPL3 AVIL RAB37	2.30e-04	169	145	5	6f765e142d127545e622fe24b5287cd6e9706ccc
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GJD2 APC PTPRM LHFPL5 CHD6	2.30e-04	169	145	5	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 TMTC1 PTPRM ADAMTS6 HEPHL1	2.30e-04	169	145	5	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ADAM23 ADCY3 GLUD2 ZFP69B TBL1X	2.36e-04	170	145	5	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 SYNM ADCY3 TMTC1 ADAMTS6	2.36e-04	170	145	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 SYNM ADCY3 TMTC1 ADAMTS6	2.36e-04	170	145	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 SYNM ADCY3 TMTC1 ADAMTS6	2.36e-04	170	145	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM217 DDX60 LHFPL3 THY1 RAB37	2.43e-04	171	145	5	a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|390C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L ZFP28 CEMIP DAAM1 ZNF30	2.49e-04	172	145	5	6f302ed795767a9636081dc64373f8f039ea16d2
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L ZFP28 CEMIP DAAM1 ZNF30	2.49e-04	172	145	5	fd8097299fc05390b30afaa9e6c80b1f607c27aa
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	ADAM23 CHN1 TMTC1 ADAMTS6 AIM2	2.63e-04	174	145	5	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MBOAT1 PBX4 GTF2E1 THY1 DSEL	2.77e-04	176	145	5	91ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM250 TRPM7 RPN1 EXPH5 SUZ12	2.77e-04	176	145	5	3c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 PTPRT GJA9 LRGUK EFHC1	2.77e-04	176	145	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNM CHN1 ADCY3 FGF17 TNS1	2.84e-04	177	145	5	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA4 CHN1 EFHC1 PTPRK MVB12B	2.84e-04	177	145	5	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA4 CHN1 EFHC1 PTPRK MVB12B	2.84e-04	177	145	5	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA2D2 TRPM7 EXPH5 EMX2	2.84e-04	177	145	5	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ZFAT ZIM2 ADCY3 TMTC1 AVIL	2.92e-04	178	145	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	USP43 PTPRT CEMIP PTPRK ADAMTS6	3.00e-04	179	145	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ZFAT MYOM1 EXPH5 FLRT3	3.00e-04	179	145	5	88dbec952507d84b85b08165eec80df99ed1e736
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ZFAT MYOM1 EXPH5 FLRT3	3.00e-04	179	145	5	daf8189a22786171e2b629261cf720736aa4ebdb
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZFAT HYOU1 PTPRM USP32 ZFP69B	3.00e-04	179	145	5	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZFAT PBX4 PTPRM USP32 ZFP69B	3.00e-04	179	145	5	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	COVID-19_Moderate-B_intermediate\|World / disease group, cell group and cell class	CR2 PTPRK ADAMTS6 AIM2 DNAH8	3.07e-04	180	145	5	bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	NEDD4L CACNA2D2 LHFPL3 PTPN13 PTPRK	3.07e-04	180	145	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXPH5 DDX60 GAL3ST2 CHN1 SMCR8	3.07e-04	180	145	5	5b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPM6 ADAM23 CHN1 TMTC1 AIM2	3.07e-04	180	145	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	NEDD4L PTPN13 PTPRK PTPRQ FLRT3	3.23e-04	182	145	5	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 POGLUT3 TRPM7 EXPH5 TMTC1	3.31e-04	183	145	5	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEDD4L CACNA2D2 LHFPL3 PTPN13 PTPRK	3.31e-04	183	145	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DDX60 CR2 PTPRK AIM2 DNAH8	3.31e-04	183	145	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 MYOM1 ADCY3 TMTC1 TNS1	3.31e-04	183	145	5	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	SYNM CHN1 ADCY3 ZNF676 TNS1	3.31e-04	183	145	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D2 LHFPL3 TMTC1 PTPRM TBL1X	3.31e-04	183	145	5	439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NEDD4L CACNA2D2 LHFPL3 PTPN13 PTPRK	3.40e-04	184	145	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	NEDD4L CACNA2D2 PTPN13 PTPRK FLRT3	3.48e-04	185	145	5	563b4e6d92bb5d77a3829556116a8e99aebac615
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1 TBL1X	1.05e-07	3	140	3	DOID:0050155 (implicated_via_orthology)
Disease	Uterine leiomyoma, estrogen-receptor negative breast cancer	POGLUT3 EXPH5 DDX10	1.22e-05	10	140	3	EFO_1000650, HP_0000131
Disease	acylcarnitine measurement	ACADM CACNA2D2 PTPRT PPP2R2A USH2A RSBN1L	3.31e-05	127	140	6	EFO_0005059
Disease	lifestyle measurement, anxiety disorder measurement	TMEM250 BRINP1 CSMD2 DDX10 OS9 USH2A	5.06e-05	137	140	6	EFO_0007795, EFO_0010724
Disease	autosomal recessive nonsyndromic deafness 67 (implicated_via_orthology)	LHFPL3 LHFPL5	6.68e-05	3	140	2	DOID:0110518 (implicated_via_orthology)
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	6.68e-05	3	140	2	DOID:885 (biomarker_via_orthology)
Disease	Idiopathic hypogonadotropic hypogonadism	CHD7 FGF17 FLRT3	8.10e-05	18	140	3	C0342384
Disease	adenocarcinoma (is_implicated_in)	NAT1 APC	1.33e-04	4	140	2	DOID:299 (is_implicated_in)
Disease	KDEL motif-containing protein 2 measurement	POGLUT3 EXPH5	1.33e-04	4	140	2	EFO_0801740
Disease	Aneuploidy	TRIP13 TLX1	2.21e-04	5	140	2	C0002938
Disease	Kallmann Syndrome	CHD7 FGF17 FLRT3	2.51e-04	26	140	3	C0162809
Disease	pappalysin-1 measurement	RPN1 CHD7	3.31e-04	6	140	2	EFO_0802845
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	3.31e-04	6	140	2	DOID:1825 (biomarker_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD7 CHD6	4.62e-04	7	140	2	DOID:0050834 (implicated_via_orthology)
Disease	Akinetic Petit Mal	CACNA2D2 EFHC1	4.62e-04	7	140	2	C0001890
Disease	Epilepsy, Absence, Atypical	CACNA2D2 EFHC1	4.62e-04	7	140	2	C0751124
Disease	Absence Seizure Disorder	CACNA2D2 EFHC1	4.62e-04	7	140	2	C4553705
Disease	Juvenile Absence Epilepsy	CACNA2D2 EFHC1	4.62e-04	7	140	2	C4317339
Disease	Childhood Absence Epilepsy	CACNA2D2 EFHC1	4.62e-04	7	140	2	C4281785
Disease	Epilepsy, Minor	CACNA2D2 EFHC1	4.62e-04	7	140	2	C4552765
Disease	Absence Epilepsy	CACNA2D2 EFHC1	4.62e-04	7	140	2	C0014553
Disease	disease recurrence, malaria	PTPRT PTPRM	6.14e-04	8	140	2	EFO_0001068, EFO_0004952
Disease	Adenoma, Microcystic	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205648
Disease	Adenoma, Monomorphic	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205649
Disease	Adenoma, Basal Cell	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205646
Disease	Follicular adenoma	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205647
Disease	Papillary adenoma	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205650
Disease	Adenoma, Trabecular	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0205651
Disease	Adenoma	TRPM7 APC SUZ12	6.66e-04	36	140	3	C0001430
Disease	basophil percentage of granulocytes	ATP8B4 RPN1 CHD7 IQGAP1	6.67e-04	83	140	4	EFO_0007995
Disease	Kunitz-type protease inhibitor 1 measurement	GJD2 GJA9	7.87e-04	9	140	2	EFO_0008199
Disease	cancer antigen 125 measurement	MUC16 GAL3ST2	9.81e-04	10	140	2	EFO_0010603
Disease	reaction time measurement	TMEM250 ZFAT LHFPL3 APC AGBL4 PPP2R2A PPP2R2B KMT2D PTPRK CHD6	1.22e-03	658	140	10	EFO_0008393
Disease	aspartate aminotransferase measurement	NEDD4L ATG7 CACNA2D2 TRPM7 PBX4 AGBL4 PPP2R2A IPO9 ADAMTS6 PUM3 HEPHL1 CNTN2	1.29e-03	904	140	12	EFO_0004736
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	PPP2R2A PPP2R2B	1.43e-03	12	140	2	DOID:1441 (implicated_via_orthology)
Disease	waist-hip ratio	NDST1 CPAMD8 ZFAT ATG7 APCDD1 ADAM23 ADCY3 STAT5B CEMIP AGBL4 ADAMTS6 EMX2 RSBN1L CNTN2	2.13e-03	1226	140	14	EFO_0004343
Disease	stroke outcome severity measurement	ADAM23 LHFPL3 DNAH8 MVB12B	2.16e-03	114	140	4	EFO_0009603
Disease	low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor	CSMD2 ADAMTS6	2.25e-03	15	140	2	EFO_0004611, EFO_0005658
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	2.25e-03	15	140	2	DOID:13413 (biomarker_via_orthology)
Disease	T-Cell Lymphoma	STAT5B KMT2D	2.57e-03	16	140	2	C0079772
Disease	Polyposis, Adenomatous Intestinal	APC ITIH4	2.57e-03	16	140	2	C2713442
Disease	Familial Intestinal Polyposis	APC ITIH4	2.57e-03	16	140	2	C2713443
Disease	blood nickel measurement	MYOM1 MUC16 USH2A TNS1	2.61e-03	120	140	4	EFO_0007583
Disease	colorectal cancer (is_implicated_in)	APC PTPRT PTPN13 EMX2	2.69e-03	121	140	4	DOID:9256 (is_implicated_in)
Disease	Eye Abnormalities	NDST1 APC	2.90e-03	17	140	2	C0015393
Disease	Adenomatous Polyposis Coli	APC ITIH4	2.90e-03	17	140	2	C0032580
Disease	response to opioid	MUC16 USP32 MVB12B	3.08e-03	61	140	3	EFO_0008541
Disease	4-ethylphenylsulfate measurement	ATP8B4 ADAMTS6	3.25e-03	18	140	2	EFO_0021148
Disease	congenital heart disease (implicated_via_orthology)	CHD7 KMT2D CHD6	4.36e-03	69	140	3	DOID:1682 (implicated_via_orthology)
Disease	waist circumference	APCDD1 TRPM7 ADCY3 PTPRT AGBL4 IPO9 PTPRK	4.50e-03	429	140	7	EFO_0004342
Disease	Bladder Neoplasm	NAT1 TBL1XR1 KMT2D CHD6	4.52e-03	140	140	4	C0005695
Disease	Malignant neoplasm of urinary bladder	NAT1 TBL1XR1 KMT2D CHD6	4.64e-03	141	140	4	C0005684

Protein segments in the cluster

Peptide	Gene	Start	Entry
YYLFHRSRGVDNSKI	nan	76	Q6ZS49
GFTLTHRRFNYKDNT	NAT1	236	P18440
VHRRGEYNVYSTFQS	PPP2R2B	61	Q00005
SNVLYGQHRFYGTQK	BAHCC1	146	Q9P281
YRSRGCSNQYLVTHK	B3GALT6	266	Q96L58
YSLRSQHEKAALYFQ	CDC23	341	Q9UJX2
VQYHESDTFRGYFKQ	AVIL	96	O75366
QRFSYQQRLKAAVHY	CENPS	11	Q8N2Z9
RVTFHYKRSSLSYFG	ADAM23	391	O75077
GFLLRYAVIKSNHSY	ASB7	181	Q9H672
YSVHQSAKQRERRYS	GJD2	96	Q9UKL4
DHAYNRKGFKIRYSA	CSMD2	2451	Q7Z408
NASFYRRSLDNHGYV	CACNA2D2	786	Q9NY47
HRQGFTTRYKIYREF	BRINP1	61	O60477
NKIQSHSRGEYNVYS	PPP2R2A	61	P63151
RYYRHSGFLEVNSAS	AIM2	211	O14862
YYTRHTGFKTLQELS	ARL14EP	21	Q8N8R7
YVHRNGSLFSRNCAY	FLRT3	551	Q9NZU0
RFEFSHSYSKVYAQR	GLCE	151	O94923
FQYADNRIHTSKYNI	ATP8B4	26	Q8TF62
SGRRNTYYASIAKAF	ACADM	346	P11310
YSSRRFDQQVEKYHK	DCLRE1B	516	Q9H816
LGKFYNNRAHSNYRA	CEMIP	721	Q8WUJ3
YHGSQASRRTIQLYE	CHD7	1046	Q9P2D1
CHYTGYLQDQRSTTK	ADAMTS6	131	Q9UKP5
QIREYQLYSRTSGKH	FGF17	51	O60258
RNVHSGSTFFKYYLQ	ITIH4	616	Q14624
YDREQTRYKATGLHF	IQGAP1	96	P46940
AGQERFHTITTSYYR	RAB10	66	P61026
TAGQERFRSVTHAYY	RAB37	86	Q96AX2
YGNTFQLYKSADHRT	PUM3	276	Q15397
QYERSHGQYKRSHGQ	LUZP4	186	Q9P127
RVKHITGRSAFFSYY	PLA2G2C	26	Q5R387
HEERYNFSNYKARFS	ACP7	206	Q6ZNF0
EKTYGNYYRLLTHRT	PCDHGA4	426	Q9Y5G9
GTHYQITKNRLYREN	POGLUT1	86	Q8NBL1
YTLDRNSLYVNGFTH	MUC16	13116	Q8WXI7
YGTTTLKYFQDHRNR	FAM166C	41	A6NJV1
QSFYSNREQYRQHLK	GGNBP2	656	Q9H3C7
KQTQQIDYSRGSIYH	KIAA1109	1421	Q2LD37
SLQKSLLYYESQHGR	FAM13B	711	Q9NYF5
AKIYHTNYVRNSRAV	LHFPL5	11	Q8TAF8
SVQKYHVFQRFYGNS	DDX60	531	Q8IY21
LGERSFSRQYAHIYA	POLD2	41	P49005
SRSSGRVYYFNHITN	PIN1	16	Q13526
KELYSFLHHQNRYGS	ENDOU	241	P21128
TYSVRGLYENHKFLF	DNAH8	3746	Q96JB1
SNYGNDRLGLYTFKH	NDST1	531	P52848
PRGFQENKRYESYHS	EXPH5	406	Q8NEV8
HFIFTYTREGNLRYS	LRRC42	71	Q9Y546
ILTFSYGNHKYGLNR	LRGUK	481	Q96M69
YIRAYDSHSLKQIFN	DDX18	586	Q9NVP1
HQYIYRLAGGFSRST	DMP1	81	Q13316
TYGLYSFHRGNSQRS	HIGD2A	61	Q9BW72
FRGRNSTRTDYEYQH	MVB12B	231	Q9H7P6
LYNISVRSYTRFGHG	PTPRQ	771	Q9UMZ3
NRYGNIISYDHSRVR	PTPRT	916	O14522
SSRYRYGQLIEINSH	TRIP13	201	Q15645
SHKLSNNYYCTRDGR	NDUFA7	46	O95182
QALRQRYHGFLNTSY	ACP2	81	P11117
DYRAKLSQIRQIYHS	PBX4	126	Q9BYU1
HYQKYASERTRFQTL	DAAM1	246	Q9Y4D1
TFYNDSRHLRNVYAK	GAL3ST2	176	Q9H3Q3
QRYYDSKNHQKRSIG	EXOC5	366	O00471
YPQRKVITFNRYSHD	HYOU1	476	Q9Y4L1
SLLKHYSDFFQGQRT	ATG7	211	O95352
YNLGKREINHYFSVR	CASD1	6	Q96PB1
GHYRSQFKSESAREY	C3orf84	16	H3BNL1
HRARNYYTDTSQKEA	CR2	1001	P20023
AYRNYAQHKRSGTQA	CHD6	1611	Q8TD26
KDSKRNYYSRGHRSI	GJA9	376	P57773
RLQNETSYSRVLHGY	DCAF12	56	Q5T6F0
LNHVSYGRLTFKYER	GLUD1	446	P00367
RQLTYKRQDGSYSAF	CPAMD8	1186	Q8IZJ3
YLRSQVRATYHGSFS	COL6A3	3061	P12111
YTRFQHYLDSLQKRN	AGBL4	171	Q5VU57
SLENLYQTYFKRQRH	ADCY3	61	O60266
ITRSYRFYHNNTFKA	APCDD1	91	Q8J025
NTKYHVTVRAYNRAG	CNTN2	881	Q02246
IYFYGNTFISRGHRT	HEPHL1	306	Q6MZM0
NNYRHYFLSSRALKA	MBOAT1	406	Q6ZNC8
HRSQTLSYRNGYAIV	EFHC1	26	Q5JVL4
RQHLFYGQYEGKVSS	IPO9	846	Q96P70
RYRYLGHRFQGNDTS	EMX2	126	Q04743
ANTYIHRAGRTARYK	DDX10	396	Q13206
QTRNFRLYYDGKHFV	CHN1	91	P15882
QHTYRLTSDGRTTYF	ERVFC1	126	P60507
ENTRRKFLIYSGSNY	SEC14L5	441	O43304
SIVTDYHNLKTRFNY	DSEL	716	Q8IZU8
LNHVSYGRLTFKYER	GLUD2	446	P49448
KTHNLLTTRNYIFGY	DGAT2	146	Q96PD7
VRRYKTYHGDVFSTS	PTPN13	401	Q12923
RAKNRYGNIIAYDHS	PTPRK	911	Q15262
KSYRIYFQAASRANG	PTPRM	696	P28827
KNRYGNIIAYDHSRV	PTPRM	926	P28827
SQGYYQKRQLRSRFH	RTP5	501	Q14D33
HAQVKRTYSHGTYRA	RSBN1L	446	Q6PCB5
AADGKTTRHNYYFIN	GTF2E1	81	P29083
KATQIRFHFHGQYYT	USH2A	481	O75445
GQYYTTETAVNLRHR	USH2A	491	O75445
EFRNKSYHYTDSLLQ	SYNM	336	O15061
KLSHNGIFTLYSYRD	PITRM1	911	Q5JRX3
GLYRHFDETVNRYKQ	RPN1	491	P04843
YHLAKETGYRSRSAF	FTSJ3	16	Q8IY81
KLGHYATQLQNTYDR	STAT5B	86	P51692
KAERSYHIFYQILSN	MYH4	281	Q9Y623
RLKRYHSQTYGNGSK	OS9	166	Q13438
LVYRYLQESGFSHSA	TBL1XR1	11	Q9BZK7
RRQDHTYYQGLFSTA	RIOX1	231	Q9H6W3
ADHRTQIKRGSTYYL	SMCR8	831	Q8TEV9
RSKQRHKQSLYGDYV	APC	786	P25054
FLVYRYLQESGFSHS	TBL1X	61	O60907
YTILNNHVYRRSLGK	POGLUT3	196	Q7Z4H8
EHTFVTLRKNYRGYN	TSPAN16	121	Q9UKR8
GKAFSTFSYLVQHQR	ZNF30	266	P17039
NQHKRVHTGERSYNY	ZFP28	801	Q8NHY6
QASYGTFQRVKYHTL	USP43	1096	Q70EL4
YSCNISGSLKRHYNR	ZFAT	1001	Q9P243
LSQHERIYTRENSYK	ZNF676	156	Q8N7Q3
GKGYTTASYFLLHQR	ZNF573	336	Q86YE8
QGRNKEAIYHYRTAL	TMTC1	496	Q8IUR5
RSNYTRKHFRALYNN	TRPM6	526	Q9BX84
YERFSGTYHFLRTQK	STYXL1	131	Q9Y6J8
SHLARTKYNNFDVYI	TMEM250	31	H0YL14
TNNVHYENYRSRKLA	SEPTIN7	301	Q16181
QYVARSLSHRSGGFY	SPATA20	366	Q8TB22
VEQQRTYSSGHNRLY	SUZ12	551	Q15022
GKSFSRYVSFSNHQR	ZNF587	246	Q96SQ5
SQRRYVHYFSGLLSG	TNS1	161	Q9HBL0
GKSFSRYVSFSNHQR	ZNF417	246	Q8TAU3
HRYQSRSAFLGRYLK	ZDBF2	2236	Q9HCK1
EHTYRSRTNFTSKYN	THY1	71	P04216
TYYNLKTHQRAFHGI	ZBTB4	376	Q9P1Z0
LVYRYLQESGFSHSA	TBL1Y	11	Q9BQ87
CGRVFSRNSYLIQHY	ZIM2	471	Q9NZV7
GKGFYTNSQRYSHQR	ZNF225	406	Q9UK10
RRYTKDRFTGHPYQN	TLX1	181	P31314
RYNIDLVNHSRSYTK	ZFP69B	261	Q9UJL9
GKGFRYSSQFIYHQR	ZNF227	666	Q86WZ6
ESLYYFGERRTNKTH	TPTE2	346	Q6XPS3
HITYKNRSQGNIISY	TMEM217	151	Q8N7C4
NFQGGSHSYRAKYVR	TRPM7	96	Q96QT4
YFISGRHLYELNRTN	USP32	761	Q8NFA0
FIYQSYLEAHRKTQS	ZNF560	301	Q96MR9
DNSYSLLRNKTLYFH	TMED8	306	Q6PL24
GKHFSAYSSLIYHQR	ZNF34	341	Q8IZ26
HKRGYNGLNQYLTTT	ZNF737	126	O75373
YSKQFVHSKSSQYRR	KMT2D	5376	O14686
AAKLYHTNYVRNSRA	LHFPL3	21	Q86UP9
RIRQSGYSSKYSFQD	MYO9A	946	B2RTY4
QHYDLSYRNKDVRST	MYOM1	11	P52179
SYRNKDVRSTVSHYQ	MYOM1	16	P52179
DAKGRTYYVNHNNRT	NEDD4L	396	Q96PU5