Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentIgG immunoglobulin complex

IGLC1 IGLC2 IGLC3

1.22e-0514693GO:0071735
GeneOntologyCellularComponentIgD immunoglobulin complex

IGLC1 IGLC3

1.60e-046692GO:0071738
GeneOntologyCellularComponentIgE immunoglobulin complex

IGLC1 IGLC3

1.60e-046692GO:0071742
GeneOntologyCellularComponentIgA immunoglobulin complex

IGLC1 IGLC3

1.10e-0315692GO:0071745
GeneOntologyCellularComponentIgM immunoglobulin complex

IGLC1 IGLC3

1.10e-0315692GO:0071753
Domainig

SEMA3A F11R KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.14e-05190656PF00047
DomainImmunoglobulin

SEMA3A F11R KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.14e-05190656IPR013151
DomainIG_LIKE

SEMA3A F11R IGLC3 KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.55e-03491657PS50835
DomainIg-like_dom

SEMA3A F11R IGLC3 KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.78e-03503657IPR007110
DomainIg-like_fold

SEMA3A F11R IGLC3 KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5 IL4R

3.02e-03706658IPR013783
DomainEGF_CA

FAT1 HEG1 ADGRE3

3.35e-0386653PF07645
DomainIG

SEMA3A F11R KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.41e-03421656SM00409
DomainIg_sub

SEMA3A F11R KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.41e-03421656IPR003599
DomainETS_DOMAIN_1

SPDEF ETV3L

4.25e-0328652PS00345
DomainETS_DOMAIN_2

SPDEF ETV3L

4.25e-0328652PS00346
DomainETS

SPDEF ETV3L

4.25e-0328652SM00413
DomainEts_dom

SPDEF ETV3L

4.25e-0328652IPR000418
DomainETS_DOMAIN_3

SPDEF ETV3L

4.25e-0328652PS50061
DomainEts

SPDEF ETV3L

4.25e-0328652PF00178
DomainEGF_Ca-bd_CS

FAT1 HEG1 ADGRE3

4.70e-0397653IPR018097
DomainEGF_CA

FAT1 HEG1 ADGRE3

4.97e-0399653PS01187
DomainASX_HYDROXYL

FAT1 HEG1 ADGRE3

5.12e-03100653PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT1 HEG1 ADGRE3

6.01e-03106653IPR000152
Domain-

SEMA3A NUP133 ELP2 EIPR1 ATG16L2

6.03e-033336552.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA3A NUP133 ELP2 EIPR1 ATG16L2

6.18e-03335655IPR015943
Domain-

KANSL3 TMCO4 PRSS16

8.27e-031196533.40.50.1820
DomainAB_hydrolase

KANSL3 TMCO4 PRSS16

8.27e-03119653IPR029058
DomainEGF_CA

FAT1 HEG1 ADGRE3

8.85e-03122653SM00179
DomainEGF_3

RELN FAT1 HEG1 ADGRE3

9.08e-03235654PS50026
DomainEGF

RELN FAT1 HEG1 ADGRE3

9.08e-03235654SM00181
DomainEGF-like_Ca-bd_dom

FAT1 HEG1 ADGRE3

9.25e-03124653IPR001881
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

9.87e-10869418681957
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.95e-091069412559621
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.63e-091169419664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.94e-091269420371502
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.94e-091269419181658
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.94e-091269420137308
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.94e-091269419936734
Pubmed

Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.

IGLC1 IGLC2 IGLC3

7.47e-0936932515285
Pubmed

Activating killer immunoglobulin-like receptor incompatibilities enhance graft-versus-host disease and affect survival after allogeneic hematopoietic stem cell transplantation.

KIR2DS1 KIR2DS3 KIR2DS5

7.47e-09369319500138
Pubmed

Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus.

IGLC1 IGLC2 IGLC3

7.47e-09369312077254
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5 IL4R

8.22e-093569519683555
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.00e-081369418687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.00e-081369419934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.00e-081369419120281
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.40e-081469419875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.40e-081469419421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.40e-081469415896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569420082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569419926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569419850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569420207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569419493232
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569420356536
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569420643584
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569417498266
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.90e-081569419326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669419897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669419000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669420670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669419527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669420652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669418668235
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669419279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669417868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669418643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669419309280
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669420331834
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669416403292
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

2.54e-081669420210919
Pubmed

Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup.

IGLC1 IGLC2 IGLC3

2.99e-0846936404900
Pubmed

The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution.

IGLC1 IGLC2 IGLC3

2.99e-0846934215080
Pubmed

Primary structure of the Mcg lambda chain.

IGLC1 IGLC2 IGLC3

2.99e-0846934415202
Pubmed

Immunoglobulin lambda-chains. The complete amino acid sequence of a Bence-Jones protein.

IGLC1 IGLC2 IGLC3

2.99e-0846934883841
Pubmed

[Structural rule of antibodies. Primary structure of a monoclonal immunoglobulin-L-chain of the lambda type, subgroup IV (Bence-Jones-protein Kern). V. The complete amino acid sequence and its genetic interpretation].

IGLC1 IGLC2 IGLC3

2.99e-0846935549568
Pubmed

A role for KIR gene variants other than KIR2DS1 in conferring susceptibility to psoriasis.

KIR2DS1 KIR2DS3 KIR2DS5

2.99e-08469316829306
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419032228
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769420173784
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769420173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769420483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419968064
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769420878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769420650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.31e-081769419761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869419630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869420519398
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869420200544
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869419046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869419846535
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

4.25e-081869420580654
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.38e-081969418571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.38e-081969418778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.38e-081969420600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

5.38e-081969418848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.71e-082069420193031
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.71e-082069420426625
Pubmed

In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.

KIR2DS1 KIR2DS3 KIR2DS5

7.45e-08569319410616
Pubmed

Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.

KIR2DL1 KIR2DS1 KIR2DS5

7.45e-08569318624290
Pubmed

Amino acid sequence of the (lambda) light chain of a human myeloma immunoglobulin (IgG New).

IGLC1 IGLC2 IGLC3

7.45e-0856934814727
Pubmed

The amino acid sequence of a lambda type Bence-Jones protein. 3. The complete amino acid sequence and the location of the disulfide bridges.

IGLC1 IGLC2 IGLC3

7.45e-0856934909564
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

8.28e-082169419861144
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.01e-072269420492596
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL1 KIR2DS1 KIR2DS3

2.60e-0776939430220
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

3.25e-072969420082482
Pubmed

Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes.

IGLC1 IGLC2 IGLC3

4.16e-0786933122211
Pubmed

Characterization of the two unique human anti-flavin monoclonal immunoglobulins.

IGLC1 IGLC2 IGLC3

4.16e-0786937737190
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL1 KIR2DS1 KIR2DS3

4.16e-0786939430221
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DL1 KIR2DS3 KIR2DS5

6.22e-0796937749980
Pubmed

Structure and expression of the human immunoglobulin lambda genes.

IGLC1 IGLC2 IGLC3

6.22e-0796932115572
Pubmed

Clustered arrangement of immunoglobulin lambda constant region genes in man.

IGLC1 IGLC2 IGLC3

6.22e-0796936273747
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DL1 KIR2DS1 KIR2DS3

6.22e-07969318340360
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DS1 KIR2DS3 KIR2DS5

8.88e-071069321206914
Pubmed

Natural killer cells and immune surveillance.

KIR2DL1 KIR2DS3 KIR2DS5

1.22e-061169318830515
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DL1 KIR2DS1 KIR2DS3

2.68e-061469319489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DL1 KIR2DS1 KIR2DS5

2.68e-061469318945962
Pubmed

Structure and function of immunoglobulins.

IGLC1 IGLC2 IGLC3

3.34e-061569320176268
Pubmed

Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components.

SPDEF MUC5AC IL4R

3.34e-061569325772331
Pubmed

Extracellular domain alterations impact surface expression of stimulatory natural killer cell receptor KIR2DS5.

KIR2DS1 KIR2DS5

3.88e-06269218682925
Pubmed

Involvement of CDK11B-mediated SPDEF ubiquitination and SPDEF-mediated microRNA-448 activation in the oncogenicity and self-renewal of hepatocellular carcinoma stem cells.

SPDEF CDK11B

3.88e-06269233328586
Pubmed

Association between KIR gene polymorphisms and type 1 diabetes mellitus (T1DM) susceptibility: A PRISMA-compliant meta-analysis.

KIR2DL1 KIR2DS1

3.88e-06269229384924
Pubmed

Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors.

KIR2DL1 KIR2DS1

3.88e-06269216141329
Pubmed

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model.

SEMA3A TRPV1

3.88e-06269229138447
Pubmed

Enhanced expression of SAM-pointed domain-containing Ets-like factor in chronic rhinosinusitis with nasal polyps.

SPDEF MUC5AC

3.88e-06269225376946
Pubmed

The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling.

KIR2DL1 KIR2DS1

3.88e-06269227210755
Pubmed

KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity.

KIR2DL1 KIR2DS1

3.88e-06269238240527
Pubmed

Investigation of killer cell immunoglobulin-like receptor gene diversity, KIR2DL1 and KIR2DS1.

KIR2DL1 KIR2DS1

3.88e-06269218643963
Pubmed

Efficient RNP-directed Human Gene Targeting Reveals SPDEF Is Required for IL-13-induced Mucostasis.

SPDEF MUC5AC

3.88e-06269231596609
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DL1 KIR2DS3 KIR2DS5

5.97e-061869320210918
Cytoband19q13.4

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

6.45e-067969419q13.4
Cytoband22q11.2

IGLC1 IGLC2 IGLC3

8.05e-0412069322q11.2
CytobandXq22.3

IRS4 NRK

1.14e-0333692Xq22.3
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

1.30e-0718484620
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLC1 IGLC2 IGLC3

1.70e-0389483353
GeneFamilyETS transcription factor family

SPDEF ETV3L

2.50e-0328482534
GeneFamilyADAM metallopeptidase domain containing|CD molecules

F11R KIR2DL1 KIR2DS1 KIR2DS5 IL4R

3.80e-03394485471
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DL1 KIR2DS1 KIR2DS3 KIR2DS5

8.52e-0649694M40909
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TMCO4 ARFGEF3 PRMT8 F11R PKP3 MUC5AC

3.98e-0719166605731ece7867659c662f952812805f947032fe10
ToppCellnormal_Lymph_Node-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

PKP3 ASCL5 IGLC2 IGLC3 CDH4

4.80e-06166665d638d356592325cded4a6cb549041cf2f8d3e62c
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 KISS1R PRSS16 PKP3 MUC5AC

7.50e-06182665dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 RELN FAT1 NRK CSMD3

7.91e-061846652cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 RELN FAT1 NRK CSMD3

7.91e-06184665ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 RELN FAT1 NRK CSMD3

7.91e-061846652b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 HEG1 F11R ATRX NRK

8.34e-061866650ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PRSS16 PKP3

9.01e-06189665c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PRSS16 PKP3

9.48e-0619166572dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PKP3 MUC5AC

9.97e-06193665aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A RELN IRS4 IL4R

2.41e-05113664feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3A RELN FAT1 IRS4

2.95e-05119664e868453c02dcf0e07821886b81ca739887d43c67
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-2|TCGA-Brain / Sample_Type by Project: Shred V9

ATRX AMZ1 ASCL5 CSMD3

3.81e-05127664018ffd9ff1913787cb0086a8581b399a121eaba1
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KISS1R PRSS16 CSMD3 MUC5AC

6.56e-05146664bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ARFGEF3 FAT1 MUC5AC MAGEC2

6.74e-051476645a824c89e4d045af465d7333275f8191fb29b041
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

ARFGEF3 PRSS16 SPDEF MUC5AC

8.69e-051576645fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

SEMA3A RELN CSMD3 CDH4

9.13e-051596645335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 PRDM8 AMZ1 MKRN2OS

9.58e-051616647c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MYO18A IGLC2 IGLC3 KCNK12

1.00e-041636642913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PRMT8 ATRX MYO18A CDH4

1.00e-0416366443887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MYO18A IGLC2 IGLC3 KCNK12

1.00e-04163664b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IRS4 MKRN2OS OPN5

1.07e-0462663a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IRS4 MKRN2OS OPN5

1.07e-0462663ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCell10x5'-Lung-Lymphocytic_B_plasma-Plasma_cells|Lung / Manually curated celltypes from each tissue

PRSS16 IGLC1 IGLC2 KCNK12

1.13e-04168664e8bd090de5c9fe286b08a8b314ce12cf988184f0
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TRPV1 IGLC2 IGLC3 KCNK12

1.21e-041716645636ec11ed1f7aacf98cd9e85853ee1a05bd2cf2
ToppCell10x5'-Lung-Lymphocytic_B_plasma|Lung / Manually curated celltypes from each tissue

PRSS16 IGLC1 IGLC2 KCNK12

1.24e-041726648156fb6de66a4c92ade703b71c2e9187291e50ef
ToppCellcontrol-Lymphocytic-B_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PKP3 IGLC2 IGLC3 IL4R

1.26e-0417366495af11b7d6c7dcd470943e5bdc56bed7a134e358
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

ARFGEF3 PRDM8 SPDEF MUC5AC

1.29e-041746647d2f802f493f19a068e097b2909a9000e2160266
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 F11R PKP3 BAIAP2L2

1.35e-041766648d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO18A IGLC2 IGLC3 KCNK12

1.38e-04177664ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSRB1 F11R DYNLT5 KCNK12

1.41e-04178664be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMZ1 MYO18A IGLC2 IGLC3

1.41e-0417866427d9826b83be67b780901429470ceb013e9039c0
ToppCell15-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

ARFGEF3 PRSS16 SPDEF MUC5AC

1.41e-04178664f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

ARFGEF3 PRDM8 SPDEF MUC5AC

1.44e-041796641fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRDM8 PRMT8 CALY

1.47e-041806643d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

ARFGEF3 IGLC1 IGLC2 IGLC3

1.57e-04183664ab5aaafcfd7b97330be6774be4c72611ca85257c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

ARFGEF3 IGLC1 IGLC2 IGLC3

1.57e-04183664193bfb787c1b36c8fabf4b00fafb5b398de6b999
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_large-bowel / Manually curated celltypes from each tissue

PRSS16 IGLC1 IGLC2 IGLC3

1.63e-041856642cad994207c4afc9d70f4c2d243ffbbcdbba693e
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma|GI_large-bowel / Manually curated celltypes from each tissue

PRSS16 IGLC1 IGLC2 IGLC3

1.63e-04185664989583c487d8c121e3731faf68f863ba43a582e6
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

ARFGEF3 PRDM8 FAT1 PRMT8

1.70e-04187664ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.77e-04189664979b7fa947538aa7ca4a219263da2575869a2caa
ToppCellCOVID-19-Epithelial_cells-Tuft-like|COVID-19 / group, cell type (main and fine annotations)

ARFGEF3 PKP3 SPDEF MUC5AC

1.77e-041896642ffbe79fe3c3f22b1cb4269726b9eb5519be84a7
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

ARFGEF3 PRDM8 FAT1 PRMT8

1.81e-04190664756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.81e-041906643b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

IGLC1 IGLC2 IGLC3 IL4R

1.81e-041906643d45d5011305f13634013d9eeb98f235517dd54e
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.81e-0419066456cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.81e-0419066425d4b591f75c26e404a34c42f1742d580af6598d
ToppCellfacs-Marrow-KLS-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS16 AMZ1 DYNLT5 KCNK12

1.81e-04190664c03c735a0ed850bf460a1847f5e2dd61753e577d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.81e-04190664be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.81e-04190664dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.88e-04192664f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellEnterocyte_Progenitors-C_06|Enterocyte_Progenitors / shred on cell type and cluster

SPDEF IGLC2 IGLC3 MUC5AC

1.88e-04192664b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.88e-04192664342842378c20267c5044bdd622515e8b9f895623
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.88e-04192664690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 ATRX FUBP1 MYO18A

1.88e-041926641ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NRK SPDEF KIR2DL1 CSMD3

1.92e-04193664315840bc48899f3a36d57b19197509de19716e3d
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS16 DYNLT5 KCNK12 SLC37A4

1.92e-04193664f92bbe70e6c725bfb8c08bfc2a94e375528151a3
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

IGLC1 IGLC2 IGLC3 IL4R

1.92e-04193664eb497d62a45ad77b2578b03a84cb3edc83207be5
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PKP3

1.92e-04193664af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS16 DYNLT5 KCNK12 SLC37A4

1.92e-0419366444ba79db566d0fa3bbcfe3adf9164bf8c3cb0bc3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY4 RELN HEG1 DYNLT5

1.96e-04194664cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 F11R PKP3 MUC5AC

1.96e-04194664c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.96e-0419466452aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.96e-041946646ac759828c41ffa974ee82842162caa959351dd1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.96e-041946645d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MSRB1 MIDN ADGRE3 ATG16L2

1.96e-04194664ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

1.96e-04194664bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PKP3

1.96e-04194664b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasmablast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KISS1R IGLC2 IGLC3 KCNK12

1.96e-0419466481394fda763d3ff07f3f5ee2abd94ae0c73b6d39
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRMT8 F11R PKP3

1.96e-0419466447a1369c22fcbfe00b08376eb610a61c355548db
ToppCellGoblet_1|World / shred by cell class for nasal brushing

ARFGEF3 MIDN SPDEF MUC5AC

2.00e-04195664d9e4889a2e7b7c97c07c15b043b77837739462e4
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 FAT1 PRMT8 LIMD1

2.00e-04195664dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HEG1 OPN5

2.00e-0419566498ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A ADCY4 RELN HEG1

2.00e-041956647f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellmild_COVID-19_(asymptomatic)-B_naive|World / disease group, cell group and cell class (v2)

IGLC2 IGLC3 IL4R THRAP3

2.00e-04195664e763d9a431052c03cc6d514f2736506c6667e2be
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KISS1R IGLC2 IGLC3 KCNK12

2.00e-04195664df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCellcontrol-Myeloid-Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MSRB1 MIDN ADGRE3 ATG16L2

2.04e-041966649c8623232c47af5de9f360fd5c5113362e37c6c9
ToppCellmild_COVID-19_(asymptomatic)-B_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

IGLC2 IGLC3 IL4R THRAP3

2.04e-04196664c87499aa570f8fab878c4c015e47c711a3a21e9c
ToppCell11.5-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

F11R PRSS16 PKP3 MUC5AC

2.04e-041966642648d64b0e7b59ae78182d55f32699ceea37ff8d
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

KISS1R IGLC2 IGLC3 KCNK12

2.04e-04196664a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TRPV1 PRDM8 PRSS16

2.04e-0477663a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

SEMA3A NYNRIN SPDEF MUC5AC

2.08e-0419766478ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FAT1 NRK IGLC2 IGLC3

2.08e-041976645e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEMA3A PKP3 SPDEF MUC5AC

2.08e-04197664d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEMA3A PKP3 SPDEF MUC5AC

2.08e-0419766480b05c8ad9c1edc5dea3236079372475431343fe
ToppCellCOVID-19_Mild-cDC|COVID-19_Mild / Disease condition and Cell class

APEX1 IGLC2 SLC4A3 NIT2

2.08e-0419766409045845891de79164124afb6c632e2838906006
ToppCellCOVID-19_Mild-cDC-|COVID-19_Mild / Disease condition and Cell class

APEX1 IGLC2 SLC4A3 NIT2

2.08e-0419766461d6dd023b2ba2bc76f17c06f7c30434ed865171
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

ADCY4 HEG1 PRSS16 PARP12

2.12e-0419866476d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A ADCY4 RELN PRDM8

2.12e-04198664b6fea363463c8dd7e6780c085ece4900266a6286
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KISS1R SPDEF MUC5AC BAIAP2L2

2.12e-04198664f95f38cc747fb3549a791288bf8d0518c049ac96
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ARFGEF3 PRDM8 CALY KCNK12

2.12e-04198664d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KISS1R SPDEF MUC5AC BAIAP2L2

2.12e-041986649c5d7852f03468394e726c444cac92a043fc6d0e
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3A PKP3 SPDEF MUC5AC

2.16e-04199664d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA3A PKP3 SPDEF MUC5AC

2.16e-04199664a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA3A PKP3 SPDEF MUC5AC

2.16e-04199664644197ff7e3299587881dd678836262e670ed4a8
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 PRSS16 SPDEF MUC5AC

2.16e-04199664eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

ATRX IGLC2 IGLC3 PARP12

2.16e-04199664952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SEMA3A PKP3 SPDEF MUC5AC

2.16e-041996642a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3A PKP3 SPDEF MUC5AC

2.16e-04199664fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN FAT1 HEG1 OPN5

2.20e-04200664f268cb1bb047e88913a828614b0a77871f5f8814
Diseaseresponse to sertraline, psychotic symptom measurement, response to olanzapine

TMCO4 SYNPO2

4.76e-055652EFO_0006327, EFO_0009182, GO_0097333
DiseaseCOVID-19 symptoms measurement

LIMD1 FYCO1 MUC5AC

6.35e-0535653EFO_0600019
DiseaseFVC change measurement, response to placebo

RELN AMZ1

3.67e-0413652EFO_0008344, EFO_0010339
Diseaseintellectual disability (implicated_via_orthology)

IRS4 ATRX ELP2

6.15e-0475653DOID:1059 (implicated_via_orthology)
DiseaseCOVID-19, osteoarthritis

LIMD1 FYCO1

8.85e-0420652MONDO_0005178, MONDO_0100096
Diseasemalignant astrocytoma (is_marker_for)

ATRX FUBP1

1.17e-0323652DOID:3069 (is_marker_for)
DiseaseAdenoid Cystic Carcinoma

FAT1 ATRX FANCA

1.42e-03100653C0010606
DiseaseKallmann Syndrome

SEMA3A KISS1R

1.50e-0326652C0162809
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 ATRX

1.74e-0328652DOID:5409 (is_implicated_in)
DiseaseGlioblastoma Multiforme

FAT1 ATRX TRMT11

1.91e-03111653C1621958
Diseasecervical cancer (is_implicated_in)

APEX1 FANCA

2.00e-0330652DOID:4362 (is_implicated_in)
Diseasepneumonia, COVID-19

FAT1 FYCO1 CDH4

2.01e-03113653EFO_0003106, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
AGEKSRPWSPSASYD

SLC4A3

216

P48751
WTKAVFSPDRSYALA

ATG16L2

551

Q8NAA4
PVSSAPASWKAAYEK

ANKRD34C

321

P0C6C1
SDLYPHEAWSFTFSK

AMZ1

181

Q400G9
SKSWYPRAAASDVTC

ASCL5

31

Q7RTU5
RKSSYGYHAWDAPVP

CSMD3

2611

Q7Z407
SRCLWDPKSDTFSSY

DYNLT5

146

Q8N7M0
YLESWGAAKPFAHLS

ADCY4

481

Q8NFM4
TAPDAPYTHWKQTVF

PRMT8

326

Q9NR22
DYSDKVKASHWSRSP

CDK11B

221

P21127
LPGLSHQYWSAPSDK

APEX1

111

P27695
NDHAPWFTASSYKGR

FAT1

1556

Q14517
PSDFHWSADLVALSY

NUP133

146

Q8WUM0
PSSFPSWYKDALKDV

MAGEC2

326

Q9UBF1
WFQDGPKSYLSSSAP

LIMD1

336

Q9UGP4
ASTSKATRPWYSHPV

GEMIN8

6

Q9NWZ8
AKAGTDPNSAAWAAY

FUBP1

526

Q96AE4
GSSAYLWKPPSRSSS

FYCO1

186

Q9BQS8
SSASGWFPEAYVKAL

BAIAP2L2

371

Q6UXY1
EDGSWYSPRHIVSKF

KIF27

226

Q86VH2
SEADSLAGWKPSVYH

KCNK12

201

Q9HB15
DPKSSARPADWKYQS

ODR4

156

Q5SWX8
SSPTSYWKSLAPDRS

MYO18A

2006

Q92614
HYLRDGDPFASKLSW

OPN5

16

Q6U736
AGSWHPRSYAAYALK

KISS1R

291

Q969F8
SFHDSPYEWSKSSDP

KIR2DS3

201

Q14952
TSKSPAHLFYPGETW

MUC5AC

5456

P98088
SGPDLSWLHFYRTAA

HEG1

281

Q9ULI3
SSADPWLFASLSYDG

EIPR1

356

Q53HC9
GKPRYAETWDFHVSA

RELN

1646

P78509
SFRDSPYEWSKSSDP

KIR2DS5

201

Q14953
RPPAKEGWSNAFYDS

PARP12

636

Q9H0J9
GLPFSTIAKHYSWST

SLC37A4

381

O43826
SSNPSSPAPDWYKDF

ATRX

1991

P46100
SDFYPGAVTVAWKAD

IGLC1

31

P0CG04
SPSTKWHNSYREPFE

IL4R

216

P24394
YPLSRKHGTETPAAW

CALY

151

Q9NYX4
GPSAFLSYADWFKAS

FANCA

441

O15360
AAPSSSPSAEAEYWR

ARFGEF3

1646

Q5TH69
SDFYPGAVTVAWKAD

IGLC2

31

P0DOY2
SDFYPGAVTVAWKAD

IGLC3

31

P0DOY3
AVRYSKLSDPASWLH

CDH4

541

P55283
PLTWYLDGAHTASSA

FPGS

371

Q05932
YAKPWSAHPDASSAR

KANSL3

41

Q9P2N6
DWSPDSKYFFTGSRD

ELP2

676

Q6IA86
LAFPDWAYKAESSPG

ETV3L

21

Q6ZN32
SFHDSPYEWSKSSDP

KIR2DL1

201

P43626
GDSPYAVAWALKHFS

NYNRIN

1206

Q9P2P1
AYSGFSSPRVEWKFD

F11R

51

Q9Y624
AAAAAAEPPFYKDVW

IRS4

221

O14654
SYNWDPKDAASKPSG

IRS4

846

O14654
SFRDSPYEWSKSSDP

KIR2DS1

201

Q14954
FSSRSKYAHSSPWPA

MSRB1

31

Q9NZV6
KYAHSSPWPAFTETI

MSRB1

36

Q9NZV6
IHLYAWAPKSFDEST

NRK

1336

Q7Z2Y5
YHWSPSRKAGRSDSS

MIDN

416

Q504T8
SDSSHAQFAAYWKPV

SZT2

551

Q5T011
ASKPSWRKGTYFDAI

TRMT11

291

Q7Z4G4
KYRTFSAPWAALAHS

TMCO4

291

Q5TGY1
LYATAFWPKSSAAAA

PRDM8

576

Q9NQV8
ASPARDDKASYVAWG

NIT2

206

Q9NQR4
AWDGSACSRYFPTAK

SEMA3A

536

Q14563
DSWTEAPKYEPNFAH

PHAF1

141

Q9BSU1
ISAASWPHLYGTADR

ADGRE3

481

Q9BY15
KPAYSPASWSSRSAV

PKP3

111

Q9Y446
SHLYGWDKYSNPRPS

nan

96

Q8NFD4
ASESSKPWPDATYGT

THRAP3

216

Q9Y2W1
SLPASWKYSSNVRAP

SYNPO2

906

Q9UMS6
LEDFSTSGAWLPHRY

MKRN2OS

131

H3BPM6
LSRKFTEWAYGPVHS

TRPV1

366

Q8NER1
LYPEDSSWAAKAPGA

SPDEF

66

O95238
YAGSLAAWARLKFPH

PRSS16

186

Q9NQE7