Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1E CACNB2	3.37e-04	9	62	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1E CACNB2	3.37e-04	9	62	2	GO:0099626
GeneOntologyBiologicalProcess	innate vocalization behavior	FOXP2 FOXP1	2.58e-05	3	61	2	GO:0098582
GeneOntologyCellularComponent	keratohyalin granule	FLG FLG2	8.61e-05	5	62	2	GO:0036457
Domain	Filaggrin	FLG FLG2	1.01e-05	2	60	2	IPR003303
Domain	Znf_C2H2	ZNF266 ZNF670 FOXP2 ZNF667 FOXP1 BCL11A GPATCH8 ZNF281 TRIM23 ZNF554 ZNF124	4.41e-05	805	60	11	IPR007087
Domain	FOXP-CC	FOXP2 FOXP1	6.06e-05	4	60	2	PF16159
Domain	FOXP-CC	FOXP2 FOXP1	6.06e-05	4	60	2	IPR032354
Domain	S100_CABP	FLG RPTN FLG2	8.73e-05	27	60	3	PS00303
Domain	S_100	FLG RPTN FLG2	8.73e-05	27	60	3	PF01023
Domain	S100_Ca-bd_sub	FLG RPTN FLG2	9.75e-05	28	60	3	IPR013787
Domain	S100/CaBP-9k_CS	FLG RPTN FLG2	9.75e-05	28	60	3	IPR001751
Domain	S_100	FLG RPTN FLG2	9.75e-05	28	60	3	SM01394
Domain	ZINC_FINGER_C2H2_2	ZNF266 ZNF670 FOXP2 ZNF667 FOXP1 BCL11A GPATCH8 ZNF281 ZNF554 ZNF124	1.64e-04	775	60	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF266 ZNF670 FOXP2 ZNF667 FOXP1 BCL11A GPATCH8 ZNF281 ZNF554 ZNF124	1.67e-04	777	60	10	PS00028
Domain	Znf_C2H2-like	ZNF266 ZNF670 FOXP2 ZNF667 FOXP1 BCL11A GPATCH8 ZNF281 ZNF554 ZNF124	2.04e-04	796	60	10	IPR015880
Domain	ZnF_C2H2	ZNF266 ZNF670 FOXP2 ZNF667 FOXP1 BCL11A GPATCH8 ZNF281 ZNF554 ZNF124	2.30e-04	808	60	10	SM00355
Domain	Prefoldin	UACA DISC1 TLE4	1.61e-03	72	60	3	IPR009053
Domain	Guanylate_kin	CACNB2 TJP1	3.14e-03	26	60	2	PF00625
Domain	GK/Ca_channel_bsu	CACNB2 TJP1	3.14e-03	26	60	2	IPR008145
Domain	Guanylate_kin-like_dom	CACNB2 TJP1	3.14e-03	26	60	2	IPR008144
Domain	GuKc	CACNB2 TJP1	3.14e-03	26	60	2	SM00072
Domain	CNMP_BINDING_1	PNPLA7 CNGA2	4.73e-03	32	60	2	PS00888
Domain	CNMP_BINDING_2	PNPLA7 CNGA2	4.73e-03	32	60	2	PS00889
Domain	cNMP	PNPLA7 CNGA2	5.33e-03	34	60	2	SM00100
Domain	cNMP_binding	PNPLA7 CNGA2	5.33e-03	34	60	2	PF00027
Domain	cNMP-bd_dom	PNPLA7 CNGA2	5.64e-03	35	60	2	IPR000595
Domain	CNMP_BINDING_3	PNPLA7 CNGA2	5.64e-03	35	60	2	PS50042
Domain	KRAB	ZNF266 ZNF670 ZNF667 ZNF554 ZNF124	5.80e-03	358	60	5	PS50805
Domain	-	ZNF266 ZNF670 ZNF667 BCL11A ZNF281 ZNF554 ZNF124	5.91e-03	679	60	7	3.30.160.60
Domain	EF_HAND_2	FLG CACNA1E RPTN FLG2	6.47e-03	231	60	4	PS50222
Domain	EF_hand_dom	FLG CACNA1E RPTN FLG2	6.57e-03	232	60	4	IPR002048
Domain	KRAB	ZNF266 ZNF670 ZNF667 ZNF554 ZNF124	6.58e-03	369	60	5	SM00349
Domain	zf-C2H2	ZNF266 ZNF670 ZNF667 BCL11A ZNF281 ZNF554 ZNF124	6.59e-03	693	60	7	PF00096
Domain	cNMP-bd-like	PNPLA7 CNGA2	6.62e-03	38	60	2	IPR018490
Domain	Znf_C2H2/integrase_DNA-bd	ZNF266 ZNF670 ZNF667 BCL11A ZNF281 ZNF554 ZNF124	6.64e-03	694	60	7	IPR013087
Domain	KRAB	ZNF266 ZNF670 ZNF667 ZNF554 ZNF124	6.65e-03	370	60	5	IPR001909
Domain	TF_fork_head_CS_2	FOXP2 FOXP1	9.59e-03	46	60	2	IPR030456
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NHSL1 ARHGEF28 TJP1 CEP85L STARD9 RABEP1 FIP1L1 AKAP13 CBARP ITPRID2 PRAG1 ENKD1 C6orf132	4.01e-09	861	63	13	36931259
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	LEO1 UACA STARD9 FIP1L1 AKAP13 TMEM131 ITPRID2 PRAG1	2.94e-07	361	63	8	30344098
Pubmed	Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling.	FOXP2 FOXP1 BCL11A SIM1	2.96e-07	31	63	4	34095148
Pubmed	Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.	FOXP2 TLE4 FOXP1 BCL11A	4.35e-07	34	63	4	34963132
Pubmed	Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain.	FOXP2 FOXP1	3.23e-06	2	63	2	30031127
Pubmed	Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion.	FOXP2 FOXP1	3.23e-06	2	63	2	30104377
Pubmed	The DISC1 promoter: characterization and regulation by FOXP2.	FOXP2 DISC1	3.23e-06	2	63	2	22434823
Pubmed	Investigating protein-protein interactions in live cells using bioluminescence resonance energy transfer.	FOXP2 FOXP1	3.23e-06	2	63	2	24893771
Pubmed	Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction.	FOXP2 FOXP1	3.23e-06	2	63	2	15056695
Pubmed	A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment.	FOXP2 FOXP1	3.23e-06	2	63	2	25853299
Pubmed	FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.	FOXP2 FOXP1	3.23e-06	2	63	2	27224915
Pubmed	Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.	FOXP2 FOXP1	3.23e-06	2	63	2	11358962
Pubmed	Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders.	FOXP2 FOXP1	3.23e-06	2	63	2	28741757
Pubmed	Compensation between FOXP transcription factors maintains proper striatal function.	FOXP2 FOXP1	3.23e-06	2	63	2	38761373
Pubmed	Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.	FLG FLG2	3.23e-06	2	63	2	24813994
Pubmed	Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder.	FOXP2 FOXP1	3.23e-06	2	63	2	26647308
Pubmed	Interaction network of human early embryonic transcription factors.	FOXP2 TLE4 BRD9 FOXP1 BCL11A FLG2 ZNF281	3.42e-06	351	63	7	38297188
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	FOXP2 TLE4 FOXP1 BCL11A SIM1	3.99e-06	130	63	5	19386638
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TJP1 FIP1L1 ANKRD28 FNDC3A AKAP13 CHD1 TMEM131 GPATCH8 CWC25	6.69e-06	733	63	9	34672954
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MEIOC TJP1 FIP1L1 TMEM131 FAM135A C6orf132	8.36e-06	263	63	6	34702444
Pubmed	Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.	FOXP2 FOXP1 SIM1	8.51e-06	22	63	3	38160393
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E CACNB2 PLPPR4 FOXP2 UACA TJP1 RABEP1 ANKRD28 BCL11A SIPA1	8.55e-06	963	63	10	28671696
Pubmed	Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.	FOXP2 FOXP1	9.68e-06	3	63	2	14516685
Pubmed	Human-specific transcriptional regulation of CNS development genes by FOXP2.	FOXP2 FOXP1	9.68e-06	3	63	2	19907493
Pubmed	Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.	FOXP2 FOXP1	9.68e-06	3	63	2	28507505
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	FLG FLG2	9.68e-06	3	63	2	23403047
Pubmed	GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.	FLG FLG2	9.68e-06	3	63	2	28928464
Pubmed	Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.	FOXP2 FOXP1	9.68e-06	3	63	2	12687690
Pubmed	Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.	FLG FLG2	9.68e-06	3	63	2	32437351
Pubmed	Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.	FOXP2 FOXP1	9.68e-06	3	63	2	25027557
Pubmed	Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization.	FOXP2 FOXP1	9.68e-06	3	63	2	28204507
Pubmed	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.	FOXP2 FOXP1	1.93e-05	4	63	2	14701752
Pubmed	Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs.	FOXP2 FOXP1	1.93e-05	4	63	2	33525513
Pubmed	Identification and characterization of T reg-like cells in zebrafish.	FOXP2 FOXP1	1.93e-05	4	63	2	29066577
Pubmed	Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.	CACNA1E FOXP2 TLE4	2.46e-05	31	63	3	27321927
Pubmed	Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum.	FOXP2 FOXP1 BCL11A	2.71e-05	32	63	3	35156680
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FOXP2 UACA BRD9 FIP1L1 ANKRD28 FOXP1 BCL11A SIPA1 ZNF281 ENKD1	3.03e-05	1116	63	10	31753913
Pubmed	The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex.	FOXP2 FOXP1	3.22e-05	5	63	2	27383233
Pubmed	Human transcription factor protein interaction networks.	FLG FOXP2 TLE4 BRD9 FIP1L1 ANKRD28 FOXP1 BCL11A GPATCH8 FLG2 ZNF281	4.68e-05	1429	63	11	35140242
Pubmed	Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype.	FLG FLG2	4.82e-05	6	63	2	27304082
Pubmed	CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia.	TJP1 CX3CR1	4.82e-05	6	63	2	36753421
Pubmed	Generation of mice with a conditional Foxp2 null allele.	FOXP2 FOXP1	4.82e-05	6	63	2	17619227
Pubmed	Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.	BRD9 BCL11A	4.82e-05	6	63	2	23644491
Pubmed	Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.	FOXP2 FOXP1	4.82e-05	6	63	2	28591638
Pubmed	Cre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleus.	FOXP2 FOXP1	4.82e-05	6	63	2	18206388
Pubmed	Delayed cortical development in mice with a neural specific deletion of β1 integrin.	TLE4 BCL11A	4.82e-05	6	63	2	37250402
Pubmed	The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.	FOXP2 TLE4	4.82e-05	6	63	2	16680166
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	RABEP1 LAMB2 ITPRID2 TRIM23	6.43e-05	118	63	4	21078624
Pubmed	Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.	FOXP2 TJP1 FOXP1	6.64e-05	43	63	3	27664421
Pubmed	Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.	FOXP2 FOXP1	6.74e-05	7	63	2	20185820
Pubmed	Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.	FOXP2 TLE4 FOXP1	7.61e-05	45	63	3	22696295
Pubmed	BRN2 as a key gene drives the early primate telencephalon development.	FOXP2 TJP1	8.98e-05	8	63	2	35245119
Pubmed	Tangential migration of corridor guidepost neurons contributes to anxiety circuits.	FOXP2 FOXP1	8.98e-05	8	63	2	28921616
Pubmed	Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths.	TJP1 LAMB2	8.98e-05	8	63	2	10482238
Pubmed	Expression of forkhead box transcription factor genes Foxp1 and Foxp2 during jaw development.	FOXP2 FOXP1	8.98e-05	8	63	2	26969076
Pubmed	Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.	FOXP2 TLE4 FOXP1 BCL11A	1.05e-04	134	63	4	19030180
Pubmed	Foxg1 suppresses early cortical cell fate.	FOXP2 FOXP1	1.15e-04	9	63	2	14704420
Pubmed	Temporally Distinct Roles for the Zinc Finger Transcription Factor Sp8 in the Generation and Migration of Dorsal Lateral Ganglionic Eminence (dLGE)-Derived Neuronal Subtypes in the Mouse.	FOXP2 FOXP1	1.15e-04	9	63	2	33230547
Pubmed	Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth.	FOXP2 FOXP1	1.15e-04	9	63	2	16387638
Pubmed	Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.	TLE4 BCL11A	1.15e-04	9	63	2	28935710
Pubmed	Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.	FOXP2 TLE4 FOXP1	1.39e-04	55	63	3	32561725
Pubmed	Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2.	FOXP2 FOXP1	1.44e-04	10	63	2	26071365
Pubmed	Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.	FOXP2 FOXP1	1.44e-04	10	63	2	28384713
Pubmed	Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes.	FOXP2 FOXP1	1.44e-04	10	63	2	26245956
Pubmed	Foxp1/2/4 regulate endochondral ossification as a suppresser complex.	FOXP2 FOXP1	1.76e-04	11	63	2	25527076
Pubmed	Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.	FIP1L1 GPATCH8	1.76e-04	11	63	2	14729963
Pubmed	MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing.	FOXP2 FOXP1	1.76e-04	11	63	2	31240265
Pubmed	A high-density association screen of 155 ion transport genes for involvement with common migraine.	CACNA1E CACNB2	2.11e-04	12	63	2	18676988
Pubmed	Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.	FOXP2 FOXP1	2.11e-04	12	63	2	20181597
Pubmed	ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling.	RNF220 SIM1	2.11e-04	12	63	2	31336385
Pubmed	Cell type-selective expression of the zinc finger-containing gene Nolz-1/Zfp503 in the developing mouse striatum.	FOXP2 FOXP1	2.11e-04	12	63	2	23684982
Pubmed	The tumor suppressor Pml regulates cell fate in the developing neocortex.	FOXP2 FOXP1	2.49e-04	13	63	2	19136970
Pubmed	Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex.	FOXP2 TLE4	2.49e-04	13	63	2	23283686
Pubmed	Genetic dissection of the glutamatergic neuron system in cerebral cortex.	FOXP2 TLE4	2.49e-04	13	63	2	34616069
Pubmed	Foxp1 regulation of neonatal vocalizations via cortical development.	FOXP2 FOXP1	2.49e-04	13	63	2	29138280
Pubmed	Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.	FOXP2 FOXP1	2.49e-04	13	63	2	22115757
Pubmed	A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors.	FOXP2 FOXP1	2.49e-04	13	63	2	35915089
Pubmed	The exon junction complex component Magoh controls brain size by regulating neural stem cell division.	FOXP2 FOXP1	2.49e-04	13	63	2	20364144
Pubmed	Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.	FOXP2 FOXP1	2.90e-04	14	63	2	15964824
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	WASHC4 TJP1 FIP1L1 TMEM131 ITPRID2 SIPA1	3.00e-04	503	63	6	36217030
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	UACA TJP1 BRD9 FIP1L1 AKAP13 TMEM131 ZNF281	3.31e-04	724	63	7	36232890
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1E CACNB2	3.34e-04	15	63	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1E CACNB2	3.34e-04	15	63	2	24453333
Pubmed	Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex.	FOXP2 TLE4	3.34e-04	15	63	2	37348506
Pubmed	Characterization of Foxp2-expressing cells in the developing spinal cord.	FOXP2 FOXP1	3.34e-04	15	63	2	19463901
Pubmed	Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex.	FOXP2 FOXP1	3.81e-04	16	63	2	26235615
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	TJP1 LAMB2	3.81e-04	16	63	2	17601529
Pubmed	The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.	FOXP2 FOXP1	3.81e-04	16	63	2	26021489
Pubmed	Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain.	FOXP2 FOXP1	3.81e-04	16	63	2	16376864
Pubmed	Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes.	FOXP2 FOXP1	3.81e-04	16	63	2	29255003
Pubmed	Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.	FOXP2 FOXP1	3.81e-04	16	63	2	22542185
Pubmed	Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex.	FOXP2 FOXP1	4.32e-04	17	63	2	22017987
Pubmed	Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex.	FOXP2 TLE4	4.32e-04	17	63	2	18940588
Pubmed	Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.	FOXP1 SIM1	4.32e-04	17	63	2	26187199
Pubmed	Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons.	FOXP2 TLE4	4.85e-04	18	63	2	34161768
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RNF220 WASHC4 LEO1 TJP1 CEP85L RABEP1 FIP1L1 TMEM131 DALRD3	4.90e-04	1285	63	9	35914814
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TJP1 FIP1L1 ANKRD28 CBARP FLG2 FAM135A TRIM23	5.05e-04	777	63	7	35844135
Pubmed	Impact of ancestry and common genetic variants on QT interval in African Americans.	CEP85L FOXP1	5.41e-04	19	63	2	23166209
Pubmed	Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity.	FOXP2 TLE4	5.41e-04	19	63	2	37561632
Pubmed	Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.	FOXP1 SIM1	5.41e-04	19	63	2	31427287
Interaction	YWHAG interactions	NHSL1 ARHGEF28 UACA TJP1 CEP85L STARD9 RABEP1 DISC1 FIP1L1 AKAP13 CBARP ITPRID2 SIPA1 PRAG1 ENKD1 C6orf132	9.76e-07	1248	63	16	int:YWHAG
Interaction	YWHAH interactions	NHSL1 ARHGEF28 UACA TJP1 CEP85L STARD9 RABEP1 AKAP13 CBARP ITPRID2 SIPA1 PRAG1 ENKD1 C6orf132	5.93e-06	1102	63	14	int:YWHAH
Interaction	YWHAQ interactions	NHSL1 ARHGEF28 UACA TJP1 CEP85L STARD9 RABEP1 DISC1 AKAP13 CBARP ITPRID2 SIPA1 ENKD1 C6orf132	7.00e-06	1118	63	14	int:YWHAQ
Interaction	PPP1CC interactions	LEO1 UACA STARD9 ZNF667 FIP1L1 AKAP13 TMEM131 CBARP ITPRID2 PRAG1 ENKD1	1.60e-05	738	63	11	int:PPP1CC
Interaction	CCDC13 interactions	ZNF670 DISC1 ENKD1 TRIM23	2.26e-05	53	63	4	int:CCDC13
Interaction	FEV interactions	FOXP2 TLE4 FOXP1 BCL11A GPATCH8 ZNF281	4.09e-05	203	63	6	int:FEV
Interaction	YWHAZ interactions	NHSL1 ARHGEF28 UACA TJP1 CEP85L STARD9 RABEP1 DISC1 ANKRD28 AKAP13 CBARP ITPRID2 SIPA1 C6orf132	4.45e-05	1319	63	14	int:YWHAZ
Interaction	YWHAB interactions	NHSL1 ARHGEF28 UACA TJP1 CEP85L STARD9 RABEP1 AKAP13 CBARP ITPRID2 SIPA1 C6orf132	6.11e-05	1014	63	12	int:YWHAB
Interaction	GATAD2B interactions	FOXP2 DISC1 FOXP1 TMEM131 BCL11A CWC25	1.16e-04	245	63	6	int:GATAD2B
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG RPTN FLG2	3.49e-07	7	40	3	1350
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF266 ZNF670 ZNF667 BCL11A ZNF281 ZNF554 ZNF124	8.98e-04	718	40	7	28
GeneFamily	EF-hand domain containing	FLG CACNA1E RPTN FLG2	1.36e-03	219	40	4	863
GeneFamily	Calcium voltage-gated channel subunits	CACNA1E CACNB2	1.50e-03	26	40	2	253
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB2 TJP1	1.50e-03	26	40	2	904
GeneFamily	Forkhead boxes	FOXP2 FOXP1	4.07e-03	43	40	2	508
Coexpression	CUI_TCF21_TARGETS_2_DN	WASHC4 FOXP2 UACA CDKL2 CEP85L TLE4 RNFT1 FNDC3A ITPRID2 FAM135A TRIM23	5.40e-06	854	63	11	M1533
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	CACNB2 ARHGEF28 SHOC1 FOXP1 FNDC3A	3.29e-05	152	63	5	M39239
Coexpression	CUI_TCF21_TARGETS_2_DN	FOXP2 UACA CDKL2 CEP85L TLE4 RNFT1 FNDC3A ITPRID2 FAM135A TRIM23	4.75e-05	888	63	10	MM1018
Coexpression	GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP	CACNB2 RGS18 BRD9 FNDC3A PNPLA7	5.30e-05	168	63	5	M6874
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	CACNA1E CACNB2 TLE4 RNFT1 FOXP1 AKAP13 SIM1 CWC25 DCAF4 TRIM23	5.78e-05	909	63	10	M41018
CoexpressionAtlas	kidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500	UACA CDKL2 TJP1 CEP85L RNFT1	1.74e-05	110	62	5	gudmap_kidney_adult_Podocyte_MafB_k1_500
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E CACNB2 PLPPR4 FOXP2 BCL11A	5.96e-06	182	63	5	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E CACNB2 PLPPR4 FOXP2 BCL11A	5.96e-06	182	63	5	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E CACNB2 PLPPR4 FOXP2 BCL11A	7.16e-06	189	63	5	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E CACNB2 PLPPR4 FOXP2 BCL11A	7.16e-06	189	63	5	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E CACNB2 PLPPR4 FOXP2 BCL11A	7.34e-06	190	63	5	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 FOXP2 CDKL2 SIM1 PRAG1	8.12e-06	194	63	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	UACA TJP1 FOXP1 ITPRID2 FAM135A	9.41e-06	200	63	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	UACA TJP1 CEP85L TLE4 KCNMB4	9.41e-06	200	63	5	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF28 UACA TJP1 TLE4 KCNMB4	9.41e-06	200	63	5	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	UACA TJP1 FOXP1 ITPRID2 FAM135A	9.41e-06	200	63	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Control-NK\|World / Disease group and Cell class	NHSL1 ZNF667 KCNMB4 BCL11A	5.04e-05	143	63	4	fe08adc9472dfd4242497d6c614d0490713261da
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FOXP2 GAS2L3 TLE4 KCNMB4	5.32e-05	145	63	4	8abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCell	droplet-Thymus-nan-18m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKL2 PGAP1 BCL11A SIPA1	7.24e-05	157	63	4	a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAPBPL PGAP1 FIP1L1 PRAG1	7.42e-05	158	63	4	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNB2 DRP2 ZNF266 FOXP2	7.98e-05	161	63	4	8aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNB2 DRP2 ZNF266 FOXP2	7.98e-05	161	63	4	deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell	Control-NK\|Control / Disease group and Cell class	NHSL1 ZNF667 BCL11A ENKD1	9.41e-05	168	63	4	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E FOXP1 KCNMB4 BCL11A	1.01e-04	171	63	4	584a095ddcbf78aa29527f84b46b5ad3e2edbaa9
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E FOXP1 KCNMB4 BCL11A	1.01e-04	171	63	4	20ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXP2 TLE4 KCNMB4 PNPLA7	1.15e-04	177	63	4	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNB2 UACA ZNF667 BCL11A	1.15e-04	177	63	4	ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGEF28 GAS2L3 AKAP13 KCNMB4	1.18e-04	178	63	4	b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Late_pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	WASHC4 TLE4 BCL11A PNPLA7	1.18e-04	178	63	4	4e28a8bd5a603518bfe993712ab785308691b5ff
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ZNF667 FOXP1 BCL11A PNPLA7	1.18e-04	178	63	4	71ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAD51AP2 RNF220 ARHGEF28 FOXP2	1.20e-04	179	63	4	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	CACNB2 ZNF266 DISC1 PGAP1	1.20e-04	179	63	4	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CEP85L SHOC1 KCNMB4 BCL11A	1.20e-04	179	63	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP1 FOXP1 CHD1 CX3CR1	1.28e-04	182	63	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	CACNB2 SHOC1 FOXP1 SIM1	1.31e-04	183	63	4	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 CACNA1E FOXP2 LAMB2	1.36e-04	185	63	4	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	droplet-Lung-nan-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PGAP1 FOXP1 BCL11A	1.36e-04	185	63	4	d4076294571557c223f5b68244e9c53e1d8f0343
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLG TJP1 RPTN C6orf132	1.36e-04	185	63	4	f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 CACNA1E FOXP2 LAMB2	1.36e-04	185	63	4	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 ARHGEF28 SHOC1 FOXP1	1.39e-04	186	63	4	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NHSL1 ARHGEF28 LAMB2 FAM135A	1.39e-04	186	63	4	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NHSL1 ARHGEF28 LAMB2 FAM135A	1.39e-04	186	63	4	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CACNB2 CDKL2 DISC1 PGAP1	1.42e-04	187	63	4	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP1 FOXP1 BCL11A SIPA1	1.42e-04	187	63	4	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	facs-Spleen-nan-3m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP1 FOXP1 BCL11A SIPA1	1.42e-04	187	63	4	3ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CACNB2 ZNF266 CDKL2 DISC1	1.48e-04	189	63	4	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	WASHC4 UACA ZNF667 BCL11A	1.48e-04	189	63	4	e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NHSL1 CACNA1E FOXP2 LAMB2	1.51e-04	190	63	4	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	UACA ZNF667 FOXP1 BCL11A	1.51e-04	190	63	4	441770ce7b3c81f36f5b15b8e51794f736462457
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NHSL1 CACNA1E FOXP2 LAMB2	1.51e-04	190	63	4	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	facs-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 AKAP13 ITPRID2 FAM135A	1.51e-04	190	63	4	719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NHSL1 CACNA1E FOXP2 LAMB2	1.51e-04	190	63	4	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	BL-critical-LOC-Epithelial-Squamous\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLG TJP1 RPTN C6orf132	1.54e-04	191	63	4	3f9b8c4fb72ae6f3167b187e6715c4dcb3159f98
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NHSL1 RNF220 FOXP2 BCL11A	1.54e-04	191	63	4	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TLE4 CHD1 BCL11A PNPLA7	1.54e-04	191	63	4	40813c397f533c2f4a6359a77757f736b6d9e07d
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TLE4 FOXP1 BCL11A PNPLA7	1.54e-04	191	63	4	054fa0493b00149313c243d39cf39a264044f074
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	UACA ZNF667 FOXP1 BCL11A	1.54e-04	191	63	4	b374676ac90572d65895052d46469906e2b6fd93
ToppCell	droplet-Fat-Gat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 UACA TJP1 PRAG1	1.57e-04	192	63	4	c312e39003c51503c9f648332fb5c6218f33f99b
ToppCell	ASK452-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	LEO1 ANKRD28 FOXP1 AKAP13	1.57e-04	192	63	4	8269b88ff6073a908f547fcc7c5941f2e8289694
ToppCell	droplet-Fat-Gat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 UACA TJP1 PRAG1	1.57e-04	192	63	4	df09056f0e562f53b6fb30b674d2d83e9eb857d0
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA TJP1 CEP85L TLE4	1.57e-04	192	63	4	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3A AKAP13 PRAG1 C6orf132	1.57e-04	192	63	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NHSL1 RNF220 FOXP2 CDKL2	1.57e-04	192	63	4	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	droplet-Fat-Gat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 UACA TJP1 PRAG1	1.57e-04	192	63	4	133b3ad251d72ff31e45e1dc6217945516ac63de
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PLPPR4 CBARP BCL11A	1.60e-04	193	63	4	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PLPPR4 CBARP BCL11A	1.60e-04	193	63	4	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA TJP1 CEP85L TLE4	1.60e-04	193	63	4	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3A AKAP13 FAM135A C6orf132	1.64e-04	194	63	4	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3A AKAP13 FAM135A C6orf132	1.64e-04	194	63	4	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PLPPR4 CBARP BCL11A	1.67e-04	195	63	4	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 FOXP2 CDKL2 SIM1	1.70e-04	196	63	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	NHSL1 CEP85L PGAP1 BCL11A	1.70e-04	196	63	4	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNB2 FOXP2 FOXP1 BCL11A	1.74e-04	197	63	4	2a90422ba400b951517603a916f34221056d0f3d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UACA TJP1 STARD9 LAMB2	1.74e-04	197	63	4	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	NHSL1 PGAP1 BCL11A PRAG1	1.77e-04	198	63	4	32d58379a89be19b6b1a494bf033416546771c19
ToppCell	Caecum-(6)_Macrophage-(61)_LYVE1_Macrophage\|Caecum / shred on region, Cell_type, and subtype	NHSL1 GAS2L3 LAMB2 CX3CR1	1.77e-04	198	63	4	e684c3934c163aef4d284b69435832d2c9614f2a
ToppCell	Caecum-Macrophage-LYVE1_Macrophage\|Caecum / Region, Cell class and subclass	NHSL1 GAS2L3 LAMB2 CX3CR1	1.77e-04	198	63	4	a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	CACNA1E PLPPR4 CDKL2 FOXP1	1.80e-04	199	63	4	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	CACNA1E PLPPR4 CDKL2 FOXP1	1.80e-04	199	63	4	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	Caecum-(5)_Dendritic_cell-(50)_cDC2\|Caecum / shred on region, Cell_type, and subtype	NHSL1 RGS18 CBARP CX3CR1	1.80e-04	199	63	4	bf8a10a9db7e8e0a6e2b53747949f442fe0e581e
ToppCell	Caecum-Dendritic_cell-cDC2\|Caecum / Region, Cell class and subclass	NHSL1 RGS18 CBARP CX3CR1	1.80e-04	199	63	4	944c567307082dd54dc141e93965d46f4ec8bc1f
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	RNF220 ZNF266 ZNF670 FLG2	1.80e-04	199	63	4	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	UACA TJP1 TLE4 ITPRID2	1.84e-04	200	63	4	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	UACA TJP1 CEP85L TLE4	1.84e-04	200	63	4	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGEF28 UACA TJP1 C6orf132	1.84e-04	200	63	4	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	UACA TJP1 TLE4 ITPRID2	1.84e-04	200	63	4	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	UACA TJP1 CEP85L TLE4	1.84e-04	200	63	4	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	CACNA1E FOXP2 FOXP1 BCL11A	1.84e-04	200	63	4	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	UACA TJP1 CEP85L TLE4	1.84e-04	200	63	4	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NHSL1 CACNA1E CEP85L BCL11A	1.84e-04	200	63	4	19055194a5e0ea122f1b8fc62df44813f6843c95
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	UACA TJP1 TLE4 KCNMB4	1.84e-04	200	63	4	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	UACA TJP1 TLE4 KCNMB4	1.84e-04	200	63	4	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	UACA TJP1 CEP85L TLE4	1.84e-04	200	63	4	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	severe-B_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UACA ZNF667 FOXP1 BCL11A	1.84e-04	200	63	4	306df1f498ac2188eaf9f2a8d002bb73bdb9642d
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FOXP2 RABEP1 AKAP13 CX3CR1	1.84e-04	200	63	4	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGEF28 UACA TJP1 C6orf132	1.84e-04	200	63	4	ecbe89ff95d046155b984c8c150e0b9e7278f839
Disease	Apraxia, Gestural	FOXP2 BCL11A	4.20e-06	2	61	2	C0422892
Disease	Apraxia, Facial-Oral	FOXP2 BCL11A	4.20e-06	2	61	2	C0750928
Disease	Apraxia, Developmental Verbal	FOXP2 BCL11A	4.20e-06	2	61	2	C0750927
Disease	Apraxia, Motor	FOXP2 BCL11A	4.20e-06	2	61	2	C0234527
Disease	Dressing Apraxia	FOXP2 BCL11A	4.20e-06	2	61	2	C0234529
Disease	Ideational Apraxia	FOXP2 BCL11A	4.20e-06	2	61	2	C0234526
Disease	Apraxia, Articulatory	FOXP2 BCL11A	4.20e-06	2	61	2	C3495144
Disease	Apraxia, Oral	FOXP2 BCL11A	4.20e-06	2	61	2	C0454608
Disease	Apraxias	FOXP2 BCL11A	4.20e-06	2	61	2	C0003635
Disease	Apraxia, Verbal	FOXP2 BCL11A	4.20e-06	2	61	2	C0349391
Disease	Apraxia of Phonation	FOXP2 BCL11A	1.26e-05	3	61	2	C0264611
Disease	schizophrenia (is_implicated_in)	FOXP2 DISC1 FOXP1 BCL11A	2.10e-05	78	61	4	DOID:5419 (is_implicated_in)
Disease	specific developmental disorder (implicated_via_orthology)	FOXP2 FOXP1	2.52e-05	4	61	2	DOID:0060038 (implicated_via_orthology)
Disease	Semantic-Pragmatic Disorder	FOXP2 BCL11A	2.28e-04	11	61	2	C0454655
Disease	Auditory Processing Disorder, Central	FOXP2 BCL11A	2.28e-04	11	61	2	C0751257
Disease	Language Delay	FOXP2 BCL11A	2.28e-04	11	61	2	C0023012
Disease	Language Development Disorders	FOXP2 BCL11A	2.28e-04	11	61	2	C0023014
Disease	Speech Delay	FOXP2 BCL11A	2.28e-04	11	61	2	C0241210
Disease	autism spectrum disorder (is_implicated_in)	FOXP2 BCL11A	4.95e-04	16	61	2	DOID:0060041 (is_implicated_in)
Disease	major depressive disorder (is_implicated_in)	FOXP2 DISC1	5.60e-04	17	61	2	DOID:1470 (is_implicated_in)
Disease	childhood trauma measurement	FOXP2 FOXP1	1.13e-03	24	61	2	EFO_0007979
Disease	uveitis (biomarker_via_orthology)	TJP1 CX3CR1	1.22e-03	25	61	2	DOID:13141 (biomarker_via_orthology)
Disease	corneal topography	NHSL1 TJP1 AKAP13	1.51e-03	109	61	3	EFO_0004345

Protein segments in the cluster

Peptide	Gene	Start	Entry
RASLELHAAASDHSS	CBARP	441	Q8N350
LHAAASDHSSSGNDR	CBARP	446	Q8N350
RSDSRAAQPAHDSGH	DCAF4	31	Q8WV16
ASGTESAHFLRAHSR	ENKD1	156	Q9H0I2
HRSSSSDRSSSEDEH	CWC25	191	Q9NXE8
SAHRLNSDSGHKSDT	CACNA1E	2061	Q15878
SSLSNASERDQHHLG	BRD9	551	Q9H8M2
DDTASLDRHSSHGSD	AKAP13	1476	Q12802
LDRHSSHGSDVSLSQ	AKAP13	1481	Q12802
SDRAGRTALHHAAFS	ANKRD28	136	O15084
HVDFSSSESQRSRHG	CX3CR1	321	P49238
RDSEGHSEDSERHSG	FLG	301	P20930
HSEDSERHSGSASRN	FLG	306	P20930
EDRASHGHSADSSRQ	FLG	341	P20930
ERHGSRHQLQSADSS	FLG	706	P20930
HEQARDSSRHSASQE	FLG	1146	P20930
DDSERLSGSASRNHH	FLG	1281	P20930
SGSRHHEASSRADSS	FLG	1881	P20930
HEASSRADSSRHSQV	FLG	1886	P20930
ASSHEQARSSAGERH	FLG	1991	P20930
ASSHEQARSSAGERH	FLG	2316	P20930
GSRHHEASSRADSSG	FLG	2531	P20930
EDRAGHGHSADSSRQ	FLG	2611	P20930
HSADRSRQSGTRHAE	FLG	3266	P20930
STHEQSESAHGRTRT	FLG	3391	P20930
GSRHEQARDSSRHSA	FLG	3736	P20930
SERRSESASRNHHGS	FLG	3876	P20930
ESASRNHHGSSREQS	FLG	3881	P20930
HDDSSRDSYSSDRHL	CHD1	1536	O14646
VSGEESHHSESRARQ	DISC1	71	Q9NRI5
SHHSESRARQCGLDS	DISC1	76	Q9NRI5
RDETHGSSDHRHRES	CACNB2	591	Q08289
GLHDREAFSVHRSNS	RAD51AP2	136	Q09MP3
EHLDSTRGSVHSLDA	RABEP1	366	Q15276
SESDHNSCRSRSHSD	ARHGEF28	776	Q8N1W1
RRGSGHSESSDSEVH	FLG2	1496	Q5D862
RRSGHSESSDSEVHS	FLG2	1876	Q5D862
ASHHSGSDNHSERSD	LEO1	71	Q8WVC0
GLSLEAARHHENSSR	BCL11A	516	Q9H165
VLGRRDSDDDHSRNH	NHSL1	1371	Q5SYE7
EHNLASRRSSDDCHD	FAM135A	631	Q9P2D6
GDEDSDDASSHRLHQ	GPATCH8	816	Q9UKJ3
ARRDSSSHEETGASH	FOXP2	326	O15409
SNSRRRHESEEGDSH	FIP1L1	546	Q6UN15
HLNSEHALDDRSTAQ	FOXP1	326	Q9H334
DSIRHAHSQSAEAER	LAMB2	1331	P55268
DHLLRTASQHSDSSG	ITPRID2	496	P28290
QGSDLEDESSLRHRH	PNPLA7	1286	Q6ZV29
RASNASCLHDSRTSH	CDKL2	371	Q92772
GSLRDHSHQAEASSD	C6orf132	866	Q5T0Z8
SRDNAVSHLAAHSNS	GAS2L3	481	Q86XJ1
HSTHGRSNFRDERSS	FNDC3A	166	Q9Y2H6
NNHIRRHSIASDSGD	CEP85L	51	Q5SZL2
NSESNSRALLHSDEH	KCNMB4	91	Q86W47
AASERASSHTLRSHA	DALRD3	181	Q5D0E6
HNLRARLEAFSDHSG	DRP2	91	Q13474
DLLESQGHSNSHRTR	MEIOC	636	A2RUB1
TSCADTQSSHLHEDR	TAPBPL	446	Q9BX59
SGFHTERSESDHDSQ	SIM1	391	P81133
RHHESSFNSGDKESL	SHOC1	1396	Q5VXU9
RAHSHEEASRPAATS	SIPA1	71	Q96FS4
DSSIHHLRLSANDAE	PGAP1	796	Q75T13
ARRHRDSTSQHASSN	SPATA3	11	Q8NHX4
SPHSSATDDLHHSDR	RNF220	286	Q5VTB9
ASSRLDDGTTDHRHL	STARD9	3386	Q9P2P6
DHRTSSRPHSAADDD	CNGA2	31	Q16280
SGSDLIRHQRSHSSE	ZNF667	566	Q5HYK9
HTEGILNRNHRDASS	PLPPR4	371	Q7Z2D5
RGHSHSEARLTDDTA	RNFT1	116	Q5M7Z0
EFHEDTRSSRSGHLA	RGS18	56	Q9NS28
HDNDHQRDRDSIKSS	TLE4	191	Q04727
HPERASSARHSSEDS	TMEM131	1331	Q92545
HHRDVLLSSSSRTDD	ZNF281	191	Q9Y2X9
LLSSSSRTDDHHGTE	ZNF281	196	Q9Y2X9
QGLSSRESHAHSASE	PRAG1	521	Q86YV5
CSSSLRDHERTHTGE	ZNF124	301	Q15973
HLTSEAASGNHRLTE	UACA	526	Q9BZF9
EIQSLASDHSGRSHD	TJP1	291	Q07157
RHLDSVLSDHTRNSA	WASHC4	971	Q2M389
SSHRDRISEAHSELA	TRIM23	481	P36406
RDSHHSQPERQDRDS	RPTN	166	Q6XPR3
FSSSLRQHERSHTGE	ZNF670	236	Q9BS34
SDRSSLNQHERTHTG	ZNF554	446	Q86TJ5
SSSSFRNHERRHADE	ZNF266	531	Q14584