Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen phosphorylase activity	PYGB PYGL PYGM	2.45e-08	3	59	3	GO:0008184
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25	7.68e-08	37	59	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25	8.82e-08	38	59	5	GO:0070001
GeneOntologyMolecularFunction	1,4-alpha-oligoglucan phosphorylase activity	PYGB PYGL PYGM	2.44e-07	5	59	3	GO:0004645
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8 ERVK-7	3.98e-06	11	59	3	GO:0004523
GeneOntologyMolecularFunction	DNA photolyase activity	CRY2 CRY1	8.58e-06	2	59	2	GO:0003913
GeneOntologyMolecularFunction	DNA (6-4) photolyase activity	CRY2 CRY1	8.58e-06	2	59	2	GO:0003914
GeneOntologyMolecularFunction	deoxyribodipyrimidine photo-lyase activity	CRY2 CRY1	8.58e-06	2	59	2	GO:0003904
GeneOntologyMolecularFunction	blue light photoreceptor activity	CRY2 CRY1	8.58e-06	2	59	2	GO:0009882
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	8.71e-06	14	59	3	GO:0003964
GeneOntologyMolecularFunction	interleukin-28 receptor binding	IFNL3 IFNL1	2.57e-05	3	59	2	GO:0032003
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-8 ERVK-7	3.14e-05	21	59	3	GO:0035613
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	CRY2 ERVK-6 ERVK-8 CHD3 ERVK-7 CRY1	1.21e-04	262	59	6	GO:0140097
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	1.77e-04	37	59	3	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	1.92e-04	38	59	3	GO:0034061
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SP1 ZNF677 SP3 ATF6 SP4 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284 CRY1	2.36e-04	1244	59	12	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SP1 ZNF677 SP3 ATF6 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284 CRY1	2.72e-04	1459	59	13	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SP1 ZNF677 SP3 ATF6 SP4 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284 CRY1	2.88e-04	1271	59	12	GO:0000987
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	3.40e-04	46	59	3	GO:0016893
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 REXO5 ASTE1 ERVK-8 ERVK-7	5.97e-04	231	59	5	GO:0004518
GeneOntologyMolecularFunction	pyridoxal phosphate binding	PYGB PYGL PYGM	6.08e-04	56	59	3	GO:0030170
GeneOntologyMolecularFunction	vitamin B6 binding	PYGB PYGL PYGM	6.40e-04	57	59	3	GO:0070279
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SP1 ZNF677 SP3 ATF6 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	7.44e-04	1412	59	12	GO:0000981
GeneOntologyMolecularFunction	photoreceptor activity	CRY2 CRY1	1.13e-03	17	59	2	GO:0009881
GeneOntologyMolecularFunction	vitamin binding	PYGB PYGL PYGM SARDH	1.31e-03	161	59	4	GO:0019842
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 CAMK2A ERVK-8 CDK11A DGKI SRPK3 ERVK-7 TRRAP PTK2	1.63e-03	938	59	9	GO:0016772
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-8 ERVK-7	1.65e-03	79	59	3	GO:0004521
GeneOntologyMolecularFunction	AMP binding	PYGL PYGM	1.74e-03	21	59	2	GO:0016208
GeneOntologyMolecularFunction	flavin adenine dinucleotide binding	CRY2 SARDH CRY1	2.71e-03	94	59	3	GO:0050660
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	CRY2 ERVK-6 MRM2 ERVK-8 CHD3 ERVK-7 CRY1	2.82e-03	645	59	7	GO:0140640
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 USP42 ERVK-8 ERVK-19 ERVK-7 ERVK-25 NPEPL1	3.05e-03	654	59	7	GO:0008233
GeneOntologyMolecularFunction	FAD binding	CRY2 CRY1	7.50e-03	44	59	2	GO:0071949
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ERVK-8 ERVK-7	7.61e-03	136	59	3	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-8 ERVK-7	7.61e-03	136	59	3	GO:0004519
GeneOntologyMolecularFunction	phosphatase binding	CRY2 SFI1 PTK2 CRY1	7.69e-03	264	59	4	GO:0019902
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-8 ERVK-7	5.61e-06	13	57	3	GO:0015074
GeneOntologyBiologicalProcess	blue light signaling pathway	CRY2 CRY1	7.50e-06	2	57	2	GO:0009785
GeneOntologyBiologicalProcess	cellular response to blue light	CRY2 CRY1	7.50e-06	2	57	2	GO:0071483
GeneOntologyBiologicalProcess	negative regulation of corticosteroid hormone secretion	CRY2 CRY1	7.46e-05	5	57	2	GO:2000847
GeneOntologyBiologicalProcess	negative regulation of steroid hormone secretion	CRY2 CRY1	7.46e-05	5	57	2	GO:2000832
GeneOntologyBiologicalProcess	negative regulation of glucocorticoid secretion	CRY2 CRY1	7.46e-05	5	57	2	GO:2000850
GeneOntologyBiologicalProcess	response to blue light	CRY2 CRY1	1.12e-04	6	57	2	GO:0009637
GeneOntologyBiologicalProcess	negative regulation of glucocorticoid receptor signaling pathway	CRY2 CRY1	1.12e-04	6	57	2	GO:2000323
GeneOntologyBiologicalProcess	glycogen catabolic process	PYGB PYGL PYGM	1.23e-04	35	57	3	GO:0005980
GeneOntologyBiologicalProcess	glucan catabolic process	PYGB PYGL PYGM	1.34e-04	36	57	3	GO:0009251
GeneOntologyBiologicalProcess	polysaccharide catabolic process	PYGB PYGL PYGM	1.58e-04	38	57	3	GO:0000272
GeneOntologyBiologicalProcess	glycogen metabolic process	GRB10 PYGB PYGL PYGM	1.62e-04	99	57	4	GO:0005977
GeneOntologyBiologicalProcess	glucan metabolic process	GRB10 PYGB PYGL PYGM	1.75e-04	101	57	4	GO:0044042
GeneOntologyBiologicalProcess	energy reserve metabolic process	GRB10 PYGB PYGL PYGM	2.79e-04	114	57	4	GO:0006112
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-8 ERVK-7	3.17e-04	48	57	3	GO:0000731
GeneOntologyBiologicalProcess	embryonic process involved in female pregnancy	SP1 SP3	3.33e-04	10	57	2	GO:0060136
GeneOntologyBiologicalProcess	cellular response to type III interferon	IFNL3 IFNL1	4.06e-04	11	57	2	GO:0071358
GeneOntologyBiologicalProcess	type III interferon-mediated signaling pathway	IFNL3 IFNL1	4.06e-04	11	57	2	GO:0038196
GeneOntologyBiologicalProcess	polysaccharide metabolic process	GRB10 PYGB PYGL PYGM	4.08e-04	126	57	4	GO:0005976
GeneOntologyBiologicalProcess	regulation of glucocorticoid receptor signaling pathway	CRY2 CRY1	4.86e-04	12	57	2	GO:2000322
GeneOntologyBiologicalProcess	response to type III interferon	IFNL3 IFNL1	5.74e-04	13	57	2	GO:0034342
GeneOntologyBiologicalProcess	response to peptide hormone	CRY2 SP1 CAMK2A GRB10 CRHR2 PTK2 CRY1	6.18e-04	530	57	7	GO:0043434
GeneOntologyBiologicalProcess	regulation of endocrine process	CRY2 CRHR2 CRY1	6.43e-04	61	57	3	GO:0044060
GeneOntologyBiologicalProcess	myeloid progenitor cell differentiation	SP1 SP3	6.68e-04	14	57	2	GO:0002318
GeneOntologyBiologicalProcess	regulation of glucocorticoid secretion	CRY2 CRY1	6.68e-04	14	57	2	GO:2000849
GeneOntologyBiologicalProcess	lipid export from cell	CRY2 PLA2G3 CRY1	7.40e-04	64	57	3	GO:0140353
GeneOntologyBiologicalProcess	negative regulation of circadian rhythm	CRY2 CRY1	8.78e-04	16	57	2	GO:0042754
GeneOntologyBiologicalProcess	glucocorticoid secretion	CRY2 CRY1	8.78e-04	16	57	2	GO:0035933
GeneOntologyBiologicalProcess	enucleate erythrocyte differentiation	SP1 SP3	8.78e-04	16	57	2	GO:0043353
GeneOntologyCellularComponent	interleukin-28 receptor complex	IFNL3 IFNL1	7.79e-05	5	59	2	GO:0032002
Domain	PHOSPHORYLASE	PYGB PYGL PYGM	2.16e-08	3	53	3	PS00102
Domain	Phosphorylase	PYGB PYGL PYGM	2.16e-08	3	53	3	PF00343
Domain	Glycg_phsphrylas	PYGB PYGL PYGM	2.16e-08	3	53	3	IPR011833
Domain	Glyco_trans_35	PYGB PYGL PYGM	2.16e-08	3	53	3	IPR000811
Domain	Sp1_fam	SP1 SP3 SP4	2.55e-06	10	53	3	IPR030450
Domain	DNA_photolyase	CRY2 CRY1	7.90e-06	2	53	2	PF00875
Domain	DNA_photolyase_N	CRY2 CRY1	7.90e-06	2	53	2	IPR006050
Domain	FAD_binding_7	CRY2 CRY1	7.90e-06	2	53	2	PF03441
Domain	Cryptochr/Photolyase_FAD-bd	CRY2 CRY1	7.90e-06	2	53	2	IPR005101
Domain	PHR_CRY_ALPHA_BETA	CRY2 CRY1	7.90e-06	2	53	2	PS51645
Domain	ZINC_FINGER_C2H2_2	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	9.04e-06	775	53	11	PS50157
Domain	ZINC_FINGER_C2H2_1	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	9.27e-06	777	53	11	PS00028
Domain	Znf_C2H2-like	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	1.16e-05	796	53	11	IPR015880
Domain	Znf_C2H2	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	1.29e-05	805	53	11	IPR007087
Domain	ZnF_C2H2	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	1.34e-05	808	53	11	SM00355
Domain	-	SP1 ZNF677 SP3 SP4 ZNF142 ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	1.79e-05	679	53	10	3.30.160.60
Domain	zf-C2H2	SP1 ZNF677 SP3 SP4 ZNF142 ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	2.13e-05	693	53	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	SP1 ZNF677 SP3 SP4 ZNF142 ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	2.16e-05	694	53	10	IPR013087
Domain	INF_lambda	IFNL3 IFNL1	4.72e-05	4	53	2	IPR029177
Domain	IL28A	IFNL3 IFNL1	4.72e-05	4	53	2	PF15177
Domain	Rossmann-like_a/b/a_fold	CRY2 CRY1	6.62e-03	43	53	2	IPR014729
Domain	-	CRY2 CRY1	6.62e-03	43	53	2	3.40.50.620
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION	PYGB PYGL PYGM	1.63e-06	9	39	3	M47621
Pathway	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	PYGB PYGL PYGM	6.98e-06	14	39	3	M19193
Pathway	REACTOME_GLYCOGEN_METABOLISM	PYGB PYGL PYGM	4.32e-05	25	39	3	M27857
Pathway	WP_ESTRADIOL_REGULATION_IN_PORTOSINUSOIDAL_VASCULAR_DISEASE	SP1 SP3	7.42e-05	5	39	2	M45554
Pathway	WP_GLYCOGEN_METABOLISM	PYGB PYGL PYGM	1.10e-04	34	39	3	MM15985
Pathway	BIOCARTA_TERC_PATHWAY	SP1 SP3	1.11e-04	6	39	2	MM1564
Pathway	BIOCARTA_TERC_PATHWAY	SP1 SP3	1.11e-04	6	39	2	M22047
Pathway	BIOCARTA_CIRCADIAN_PATHWAY	CRY2 CRY1	1.11e-04	6	39	2	M22067
Pathway	WP_CORTICOTROPINRELEASING_HORMONE_SIGNALING	SP1 CAMK2A CRHR2 PTK2	1.17e-04	92	39	4	M39441
Pathway	WP_MELATONIN_METABOLISM_AND_EFFECTS	CRY2 CAMK2A CRY1	1.43e-04	37	39	3	M39418
Pathway	BIOCARTA_CIRCADIAN_PATHWAY	CRY2 CRY1	1.55e-04	7	39	2	MM1578
Pathway	BIOCARTA_TERT_PATHWAY	SP1 SP3	1.55e-04	7	39	2	MM1541
Pathway	WP_GLYCOGEN_SYNTHESIS_AND_DEGRADATION	PYGB PYGL PYGM	1.80e-04	40	39	3	M39595
Pathway	BIOCARTA_TERT_PATHWAY	SP1 SP3	2.07e-04	8	39	2	M22015
Pathway	BIOCARTA_FEEDER_PATHWAY	PYGL PYGM	2.65e-04	9	39	2	M3061
Pathway	WP_TYPE_III_INTERFERON_SIGNALING	IFNL3 IFNL1	3.31e-04	10	39	2	M39464
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	PYGB PYGL PYGM	3.94e-04	52	39	3	M14171
Pathway	KEGG_CIRCADIAN_RHYTHM_MAMMAL	CRY2 CRY1	5.71e-04	13	39	2	M18009
Pathway	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	PYGL PYGM	6.65e-04	14	39	2	MM15391
Pathway	PID_CIRCADIAN_PATHWAY	CRY2 CRY1	8.73e-04	16	39	2	M95
Pathway	WP_EGFEGFR_SIGNALING	SP1 CAMK2A GRB10 PTK2	1.01e-03	162	39	4	M39334
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	SP1 SP3 CAMK2A	1.07e-03	73	39	3	M39401
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	SP1 SP3	1.11e-03	18	39	2	M3430
Pathway	REACTOME_GLYCOGEN_METABOLISM	PYGL PYGM	1.11e-03	18	39	2	MM15577
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	SP1 SP3	1.11e-03	18	39	2	MM1385
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	SP1 SP3 CAMK2A	1.15e-03	75	39	3	M39568
Pathway	REACTOME_INTERLEUKIN_20_FAMILY_SIGNALING	IFNL3 IFNL1	1.37e-03	20	39	2	MM15496
Pubmed	Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms.	SP1 SP3 SP4	4.88e-09	3	60	3	23540600
Pubmed	Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.	SP1 SP3 SP4	4.88e-09	3	60	3	26967243
Pubmed	Curcumin decreases specificity protein expression in bladder cancer cells.	SP1 SP3 SP4	4.88e-09	3	60	3	18593936
Pubmed	Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.	SP1 SP3 SP4	4.88e-09	3	60	3	11532028
Pubmed	Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells.	SP1 SP3 SP4	4.88e-09	3	60	3	21919647
Pubmed	Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3.	SP1 SP3 SP4	4.88e-09	3	60	3	7559627
Pubmed	Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx.	SP1 SP3 SP4	1.95e-08	4	60	3	15781457
Pubmed	Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.	SP1 SP3 SP4	1.95e-08	4	60	3	27889927
Pubmed	Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.	SP1 SP3 SP4	4.87e-08	5	60	3	20538607
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-19 ERVK-7	4.87e-08	5	60	3	12629516
Pubmed	Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter.	SP1 SP3 SP4	4.87e-08	5	60	3	10547281
Pubmed	Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors.	SP1 SP3 SP4	4.87e-08	5	60	3	12560508
Pubmed	Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells.	SP1 SP3 SP4	9.73e-08	6	60	3	16201967
Pubmed	POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1.	SP1 SP3 SP4	1.70e-07	7	60	3	12004059
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25	6.29e-07	94	60	5	21542922
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19	1.06e-06	12	60	3	14557543
Pubmed	Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.	PYGB PYGL PYGM	2.19e-06	15	60	3	2575583
Pubmed	Interferon Lambda Family along with HTLV-1 Proviral Load, Tax, and HBZ Implicated in the Pathogenesis of Myelopathy/Tropical Spastic Paraparesis.	IFNL3 IFNL1	2.93e-06	2	60	2	29990995
Pubmed	Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failure.	SP1 SP3	2.93e-06	2	60	2	10825178
Pubmed	Delay in feedback repression by cryptochrome 1 is required for circadian clock function.	CRY2 CRY1	2.93e-06	2	60	2	21236481
Pubmed	CRY1, CRY2 and PRKCDBP genetic variants in metabolic syndrome.	CRY2 CRY1	2.93e-06	2	60	2	25391456
Pubmed	HPV8 activates cellular gene expression mainly through Sp1/3 binding sites.	SP1 SP3	2.93e-06	2	60	2	31299490
Pubmed	Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	20825493
Pubmed	The ratio of intracellular CRY proteins determines the clock period length.	CRY2 CRY1	2.93e-06	2	60	2	26966073
Pubmed	The Synergistic Effect of Fluvastatin and IFN-λ on Peripheral Blood Mononuclear Cells of Chronic Hepatitis C Virus (HCV) Patients with IL-28B rs12979860 CC Genotype.	IFNL3 IFNL1	2.93e-06	2	60	2	32245297
Pubmed	Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice.	CRY2 CRY1	2.93e-06	2	60	2	24187535
Pubmed	The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.	CRY2 CRY1	2.93e-06	2	60	2	19211562
Pubmed	Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.	CRY2 CRY1	2.93e-06	2	60	2	28380384
Pubmed	The expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates differently dependent on tumor location.	CRY2 CRY1	2.93e-06	2	60	2	29940771
Pubmed	Association Between IL28B, IL29 Gene Polymorphisms and Clinical Manifestations of Behçet's Disease.	IFNL3 IFNL1	2.93e-06	2	60	2	32646311
Pubmed	Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.	CRY2 CRY1	2.93e-06	2	60	2	24782829
Pubmed	Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia.	SP1 SP4	2.93e-06	2	60	2	25175639
Pubmed	Redox potential: differential roles in dCRY and mCRY1 functions.	CRY2 CRY1	2.93e-06	2	60	2	11818067
Pubmed	Circadian oscillation of nucleotide excision repair in mammalian brain.	CRY2 CRY1	2.93e-06	2	60	2	19164551
Pubmed	Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.	CRY2 CRY1	2.93e-06	2	60	2	10518585
Pubmed	Circadian intraocular pressure rhythm is generated by clock genes.	CRY2 CRY1	2.93e-06	2	60	2	16936122
Pubmed	Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.	SP1 SP3	2.93e-06	2	60	2	14766015
Pubmed	Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.	SP1 SP3	2.93e-06	2	60	2	25538045
Pubmed	Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.	CRY2 CRY1	2.93e-06	2	60	2	10217146
Pubmed	Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms.	CRY2 CRY1	2.93e-06	2	60	2	12696673
Pubmed	Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes.	CRY2 CRY1	2.93e-06	2	60	2	17073458
Pubmed	Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner.	CRY2 CRY1	2.93e-06	2	60	2	22033214
Pubmed	Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains.	CRY2 CRY1	2.93e-06	2	60	2	18614689
Pubmed	Characterization of photolyase/blue-light receptor homologs in mouse and human cells.	CRY2 CRY1	2.93e-06	2	60	2	9801304
Pubmed	Synchronization of cellular clocks in the suprachiasmatic nucleus.	CRY2 CRY1	2.93e-06	2	60	2	14631044
Pubmed	Autonomic and cardiovascular responses to scent stimulation are altered in cry KO mice.	CRY2 CRY1	2.93e-06	2	60	2	17175102
Pubmed	Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors.	SP1 SP3	2.93e-06	2	60	2	31164147
Pubmed	Measurement of internal body time by blood metabolomics.	CRY2 CRY1	2.93e-06	2	60	2	19487679
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	2.93e-06	2	60	2	9060628
Pubmed	Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus.	SP1 SP3	2.93e-06	2	60	2	17681019
Pubmed	Endothelial Sp1/Sp3 are essential to the effect of captopril on blood pressure in male mice.	SP1 SP3	2.93e-06	2	60	2	37735515
Pubmed	Further characterization of the phenotype of mCry1/mCry2-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	11587085
Pubmed	Cancer, hear my battle CRY.	CRY2 CRY1	2.93e-06	2	60	2	32291799
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	2.93e-06	2	60	2	9460924
Pubmed	Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.	SP1 SP3	2.93e-06	2	60	2	26807725
Pubmed	An Sp1/Sp3 binding polymorphism confers methylation protection.	SP1 SP3	2.93e-06	2	60	2	18725933
Pubmed	Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.	CRY2 CRY1	2.93e-06	2	60	2	32339698
Pubmed	Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide.	SP1 SP3	2.93e-06	2	60	2	15951564
Pubmed	Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.	CRY2 CRY1	2.93e-06	2	60	2	8909283
Pubmed	CRY1 and CRY2 genetic variants in seasonality: A longitudinal and cross-sectional study.	CRY2 CRY1	2.93e-06	2	60	2	27267441
Pubmed	Vagal regulation of respiratory clocks in mice.	CRY2 CRY1	2.93e-06	2	60	2	17442820
Pubmed	Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.	IFNL3 IFNL1	2.93e-06	2	60	2	21800339
Pubmed	Beyond HAT Adaptor: TRRAP Liaisons with Sp1-Mediated Transcription.	SP1 TRRAP	2.93e-06	2	60	2	34830324
Pubmed	Circadian rhythm of RNA N6-methyladenosine and the role of cryptochrome.	CRY2 CRY1	2.93e-06	2	60	2	26239657
Pubmed	Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene.	SP1 SP3	2.93e-06	2	60	2	22464952
Pubmed	Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	15893577
Pubmed	Circadian behavioral rhythms in Cry1/Cry2 double-deficient mice induced by methamphetamine.	CRY2 CRY1	2.93e-06	2	60	2	18258761
Pubmed	Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.	SP1 SP3	2.93e-06	2	60	2	19437621
Pubmed	Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.	SP1 SP3	2.93e-06	2	60	2	8845379
Pubmed	Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.	CRY2 CRY1	2.93e-06	2	60	2	20042581
Pubmed	Interval timing is intact in arrhythmic Cry1/Cry2-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	21775289
Pubmed	Control of skin cancer by the circadian rhythm.	CRY2 CRY1	2.93e-06	2	60	2	22025708
Pubmed	Circadian time-place learning in mice depends on Cry genes.	CRY2 CRY1	2.93e-06	2	60	2	18514517
Pubmed	Altered phase-relationship between peripheral oscillators and environmental time in Cry1 or Cry2 deficient mouse models for early and late chronotypes.	CRY2 CRY1	2.93e-06	2	60	2	24386234
Pubmed	Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.	CRY2 CRY1	2.93e-06	2	60	2	9822380
Pubmed	The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock.	CRY2 CRY1	2.93e-06	2	60	2	21858120
Pubmed	Serine phosphorylation of mCRY1 and mCRY2 by mitogen-activated protein kinase.	CRY2 CRY1	2.93e-06	2	60	2	15298678
Pubmed	Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.	CRY2 CRY1	2.93e-06	2	60	2	34172584
Pubmed	Increased Serum Levels of IL-28 and IL-29 and the Protective Effect of IL28B rs8099917 Polymorphism in Patients with Hashimoto's Thyroiditis.	IFNL3 IFNL1	2.93e-06	2	60	2	27617784
Pubmed	Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei.	CRY2 CRY1	2.93e-06	2	60	2	12121621
Pubmed	Expression of the blue-light receptor cryptochrome in the human retina.	CRY2 CRY1	2.93e-06	2	60	2	14507900
Pubmed	Light signalling in cryptochrome-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	14712914
Pubmed	Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.	CRY2 CRY1	2.93e-06	2	60	2	24344304
Pubmed	Postnatal constant light compensates Cryptochrome1 and 2 double deficiency for disruption of circadian behavioral rhythms in mice under constant dark.	CRY2 CRY1	2.93e-06	2	60	2	24278295
Pubmed	High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	23531614
Pubmed	Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer.	CRY2 CRY1	2.93e-06	2	60	2	16061665
Pubmed	Daily variation in the electrophysiological activity of mouse medial habenula neurones.	CRY2 CRY1	2.93e-06	2	60	2	24247982
Pubmed	Transcriptional control of human CD2AP expression: the role of Sp1 and Sp3.	SP1 SP3	2.93e-06	2	60	2	21604172
Pubmed	Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes.	SP3 SP4	2.93e-06	2	60	2	1454515
Pubmed	Deregulated expression of cryptochrome genes in human colorectal cancer.	CRY2 CRY1	2.93e-06	2	60	2	26768731
Pubmed	Expression of the human endogenous retrovirus (HERV) group HML-2/HERV-K does not depend on canonical promoter elements but is regulated by transcription factors Sp1 and Sp3.	SP1 SP3	2.93e-06	2	60	2	21248046
Pubmed	Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.	PYGB PYGM	2.93e-06	2	60	2	25130497
Pubmed	Sp1 and Sp3 activate transcription of the human dopamine transporter gene.	SP1 SP3	2.93e-06	2	60	2	15816870
Pubmed	Network features of the mammalian circadian clock.	CRY2 CRY1	2.93e-06	2	60	2	19278294
Pubmed	Sp family transcription factors regulate expression of rat D2 dopamine receptor gene.	SP1 SP3	2.93e-06	2	60	2	9628590
Pubmed	Perspectives: neurobiology. The CRYs fo flies and mice.	CRY2 CRY1	2.93e-06	2	60	2	10636810
Pubmed	Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock.	CRY2 CRY1	2.93e-06	2	60	2	12483519
Pubmed	Circadian clock cryptochrome proteins regulate autoimmunity.	CRY2 CRY1	2.93e-06	2	60	2	29109286
Pubmed	Reduced light response of neuronal firing activity in the suprachiasmatic nucleus and optic nerve of cryptochrome-deficient mice.	CRY2 CRY1	2.93e-06	2	60	2	22216107
Pubmed	The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells.	SP1 SP3	2.93e-06	2	60	2	14608051
Cytoband	19q13.13	IFNL3 IFNL1	1.69e-04	15	59	2	19q13.13
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF677 ZNF628 ZNF611 RINL ZNF284 IFNL3 IFNL1	8.22e-04	1192	59	7	chr19q13
Cytoband	7p22.1	ERVK-6 USP42	1.69e-03	47	59	2	7p22.1
Cytoband	22q12.2	PLA2G3 SFI1	2.56e-03	58	59	2	22q12.2
GeneFamily	Glycogen phosphorylases	PYGB PYGL PYGM	1.08e-08	3	41	3	437
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP1 ZNF677 SP3 SP4 ZNF142 WIZ ZNF628 ZNF611 ZNF232 ZNF879 ZNF284	3.81e-07	718	41	11	28
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP1 SP3 SP4	9.01e-07	9	41	3	755
GeneFamily	Interferons	IFNL3 IFNL1	2.38e-03	32	41	2	598
Drug	3,5-dimethylphenyl isocyanate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000521488
Drug	5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000093111
Drug	adenosine-5'-chloromethylphosphonate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000191554
Drug	hydan	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000008360
Drug	EHMF	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000033931
Drug	5'-deoxy-5'-fluoro-5'-(methylthio)adenosine	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000147839
Drug	pyridoxal 5'-methylenephosphonate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID003082249
Drug	Plp 5'-mpa	PYGB PYGL PYGM	1.33e-08	3	55	3	CID003082151
Drug	glucose-1,2-cyclic phosphate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000191723
Drug	3'-FFdUrd	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000072260
Drug	2',3',4',5,5'-pentachloro-2-biphenylol	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000119518
Drug	AC1L8XK3	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000409735
Drug	N-acetyl-N'-beta-D-glucopyranosyl urea	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000446801
Drug	NSC758405	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000003201
Drug	3,5-dinitrophenyl phosphate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000151920
Drug	riboflavin tetraacetate	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000094186
Drug	pyridoxal phosphoglucose	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000196007
Drug	2,5-dimethyl-3-furanone	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000085730
Drug	3,5-dinitrophenol	PYGB PYGL PYGM	1.33e-08	3	55	3	CID000011459
Drug	galocitabine	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000065950
Drug	2,5-anhydro-D-mannitol 1-phosphate	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000189134
Drug	AC1LAMW2	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000491364
Drug	FdUrd-C8	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000094262
Drug	Mem-CC	PYGB PYGL PYGM	5.33e-08	4	55	3	CID003081269
Drug	5-deoxyribose-1-phosphate	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000135786
Drug	ingliforib	PYGB PYGL PYGM	5.33e-08	4	55	3	CID006451325
Drug	uric acid riboside	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000164933
Drug	pseudo-dl-glucose	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000125259
Drug	BCIp4A	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000192417
Drug	pyridoxal diphosphate	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000125696
Drug	3'-chloromethotrexate	PYGB PYGL PYGM	5.33e-08	4	55	3	CID000097703
Drug	mannosylamine	MAN2B2 PYGB PYGL PYGM	7.08e-08	17	55	4	CID000192844
Drug	heptulose-2-P	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000124823
Drug	m-anisidine	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000010824
Drug	6-FPLP	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000146246
Drug	gluconohydroximo-1,5-lactone	PYGB PYGL PYGM	1.33e-07	5	55	3	CID009576855
Drug	2-hydroxypropylphosphonate	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000441028
Drug	DHPBU	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000125914
Drug	6-FDPL	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000129578
Drug	5'-isobutylthioinosine	PYGB PYGL PYGM	1.33e-07	5	55	3	CID003080910
Drug	3'-O-methylpyridoxal 5'-phosphate	PYGB PYGL PYGM	1.33e-07	5	55	3	CID003082179
Drug	GlcMan	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000152120
Drug	U66985	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000127224
Drug	indirubin-5-sulphonate	PYGB PYGL PYGM	1.33e-07	5	55	3	CID005288641
Drug	AC1O3M08	PYGB PYGL PYGM	1.33e-07	5	55	3	CID006331955
Drug	AC1LCUXJ	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000656425
Drug	6-amino-5-bromouracil	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000080578
Drug	etafenone	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000003275
Drug	ddEtUrd	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000451452
Drug	5-trifluoromethyl-2'-deoxycytidine	PYGB PYGL PYGM	1.33e-07	5	55	3	CID000125618
Drug	CV-araU	PYGB PYGL PYGM	2.65e-07	6	55	3	CID006441877
Drug	2-thiothymidine	PYGB PYGL PYGM	2.65e-07	6	55	3	CID003005944
Drug	Carbocyclic Bvdc	PYGB PYGL PYGM	2.65e-07	6	55	3	CID006438602
Drug	DNPP	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000067056
Drug	5-chloro-indole-2-carboxylic acid	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000082693
Drug	2,2-dimethyl-3-hydroxybutyric acid	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000152984
Drug	EdUMP	PYGB PYGL PYGM	2.65e-07	6	55	3	CID003085112
Drug	5'-deoxy-5'-chloroformycin	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000126430
Drug	NSC-97433	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000001803
Drug	5-n-propylthioadenosine	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000656428
Drug	AzddCyd	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000451374
Drug	5-Ffdru	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000065561
Drug	AR-L57	PYGB PYGL PYGM	2.65e-07	6	55	3	CID000156890
Drug	Carbocyclic Ivdu	PYGB PYGL PYGM	2.65e-07	6	55	3	CID006439191
Drug	alpha-(fluoromethyl)dehydroornithine	PYGB PYGL PYGM	4.64e-07	7	55	3	CID006439607
Drug	6-fluoropyridoxal	PYGB PYGL PYGM	4.64e-07	7	55	3	CID003080803
Drug	2',3'-dideoxy-3'-fluorocytidine	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000356019
Drug	heptenitol	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000188267
Drug	AC1L3372	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000108025
Drug	1 Gpt	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000101247
Drug	formycins	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000512867
Drug	Promonta	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000108494
Drug	5'-methylthioinosine	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000161214
Drug	hydantocidin	PYGB PYGL PYGM	4.64e-07	7	55	3	CID000125429
Drug	AC1NUVX5	PYGB PYGL PYGM	7.41e-07	8	55	3	CID005461894
Drug	6-methylpurine	PYGB PYGL PYGM	7.41e-07	8	55	3	CID005287547
Drug	amorphin	PYGB PYGL PYGM	7.41e-07	8	55	3	CID000122792
Drug	Etafenone [inn]	PYGB PYGL PYGM	7.41e-07	8	55	3	CID000066659
Drug	6-benzyl-2-thiouracil	PYGB PYGL PYGM	1.11e-06	9	55	3	CID000685814
Drug	5'-methylthiotubercidin	PYGB PYGL PYGM	1.11e-06	9	55	3	CID000188350
Drug	alpha-maltosyl fluoride	PYGB PYGL PYGM	1.11e-06	9	55	3	CID000194237
Drug	5-Iodoribose 1-phosphate	PYGB PYGL PYGM	1.11e-06	9	55	3	CID003035973
Drug	5'-iodo-5'-deoxyadenosine	PYGB PYGL PYGM	1.11e-06	9	55	3	CID000107502
Drug	8-azidoadenosine 5'-monophosphate	PYGB PYGL PYGM	1.58e-06	10	55	3	CID000124726
Drug	2,6-dihydroxypyridine	PYGB PYGL PYGM	1.58e-06	10	55	3	CID000069371
Drug	SP 0	SP1 SP3 SP4	1.58e-06	10	55	3	CID002742752
Drug	6-methyluridine	PYGB PYGL PYGM	1.58e-06	10	55	3	CID000092887
Drug	UDP-pyridoxal	PYGB PYGL PYGM	1.58e-06	10	55	3	CID000126789
Drug	2',3'-dideoxyadenosine	PYGB PYGL PYGM CRHR2 CRY1	1.62e-06	82	55	5	CID000020039
Drug	glucosyl fluoride	PYGB PYGL PYGM	2.17e-06	11	55	3	CID000150967
Drug	Cid 11299980	PYGB PYGL PYGM	2.17e-06	11	55	3	CID009856533
Drug	9 Da	PYGB PYGL PYGM	2.17e-06	11	55	3	CID005287565
Drug	BCX-34	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000060817
Drug	Ap4U	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000165888
Drug	phenylurethane	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000007591
Drug	acyclothymidine	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000072358
Drug	5'-deoxypyridoxal	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000164889
Drug	AC1L19D1	PYGB PYGL PYGM	2.89e-06	12	55	3	CID000000494
Drug	2-deoxy-D-ribose-1-phosphate	PYGB PYGL PYGM PTK2	3.51e-06	43	55	4	CID000000634
Drug	phenylselenenyl chloride	PYGB PYGL PYGM	3.75e-06	13	55	3	CID000021928
Disease	Color blindness	ATF6 CNGA3	3.28e-05	5	54	2	C0242225
Disease	Color vision defect	ATF6 CNGA3	3.28e-05	5	54	2	C0009398
Disease	Color Blindness, Red	ATF6 CNGA3	3.28e-05	5	54	2	C0155015
Disease	Color Blindness, Red-Green	ATF6 CNGA3	3.28e-05	5	54	2	C0155016
Disease	Color Blindness, Acquired	ATF6 CNGA3	3.28e-05	5	54	2	C0155018
Disease	Color Blindness, Green	ATF6 CNGA3	3.28e-05	5	54	2	C0239777
Disease	Monochromatopsia	ATF6 CNGA3	3.28e-05	5	54	2	C0751043
Disease	Color Blindness, Inherited	ATF6 CNGA3	3.28e-05	5	54	2	C0751042
Disease	Color Blindness, Blue	ATF6 CNGA3	4.91e-05	6	54	2	C0155017
Disease	Achromatopsia	ATF6 CNGA3	6.86e-05	7	54	2	C0152200
Disease	Seasonal Affective Disorder	CRY2 CRY1	3.88e-04	16	54	2	C0085159
Disease	brain measurement, neuroimaging measurement	DCHS2 WNT2B GRB10 DGKI PYGB PTK2	4.94e-04	550	54	6	EFO_0004346, EFO_0004464
Disease	multisite chronic pain	SP4 PTK2 CRY1	7.12e-04	95	54	3	EFO_0010100
Disease	Schizophrenia	SP1 SP4 TMEM245 ERVK-8 GRB10 TRRAP IFNL3	1.09e-03	883	54	7	C0036341
Disease	Glycogen Storage Disease	PYGL PYGM	1.12e-03	27	54	2	C0017919
Disease	hepatitis C (is_implicated_in)	IFNL3 IFNL1	1.21e-03	28	54	2	DOID:1883 (is_implicated_in)
Disease	Mental Depression	CRY2 CAMK2A CRHR2 CRY1	1.21e-03	254	54	4	C0011570
Disease	Myeloid Leukemia, Chronic	CRY2 CRY1	1.29e-03	29	54	2	C0023473
Disease	Cone-Rod Dystrophy 2	ATF6 CNGA3	1.29e-03	29	54	2	C3489532
Disease	apolipoprotein B measurement	SP1 DCHS2 SP4 PYGB PTK2 ZNF284	1.30e-03	663	54	6	EFO_0004615
Disease	Bipolar Disorder	CRY2 SP4 CAMK2A CRHR2 CRY1	1.78e-03	477	54	5	C0005586
Disease	Global developmental delay	ZNF142 CHD3 TRRAP	1.88e-03	133	54	3	C0557874
Disease	Depressive disorder	CRY2 CAMK2A CRHR2 CRY1	1.94e-03	289	54	4	C0011581
Disease	mean reticulocyte volume	SP1 SP3 C6orf89 GRB10 TPGS1 TRRAP	3.31e-03	799	54	6	EFO_0010701

Protein segments in the cluster

Peptide	Gene	Start	Entry
HPELWRLTVASHHIR	ERVK-19	336	O71037
HPELWRLTVASHHIR	ERVK-8	336	Q902F8
SHLHELSLRWHLGRR	ABCB6	351	Q9NP58
SLRLNHELRGWVHRH	ATF6	476	P18850
RRHHRILGLLNWLSH	ASTE1	251	Q2TB18
ALMILLIHWDHRLHR	OR2T12	41	Q8NG77
GQLHHLHRVPWSHVR	NPEPL1	26	Q8NDH3
LSQIRSHLHRSDPHW	KAT14	616	Q9H8E8
RKRWHRWQDHHSLRV	CRHR2	371	Q13324
ARLHHSWHFAGELQR	GOLGA6L7	126	A0A1B0GV03
HPELWRLTVASHHIR	ERVK-7	1096	P63135
LINWVALDREHRGHH	DCHS2	1246	Q6V1P9
LRQEGWIHHLARHAV	CRY2	366	Q49AN0
HPELWRLTVASHHIR	ERVK-25	336	P61570
HPELWRLTVASHHIR	ERVK-6	336	Q69384
SRSPRENFVRHHWVH	DGKI	241	O75912
ENFVRHHWVHRRRQE	DGKI	246	O75912
HRRHDYWLLAGIVLH	CHD3	1741	Q12873
HRDSWHLRHQVLLHV	CNTFR	91	P26992
QLRQEGWIHHLARHA	CRY1	346	Q16526
RPRGRLHHWLHRLQE	IFNL1	141	Q8IU54
RTRGRLHHWLHRLQE	IFNL3	146	Q8IZI9
RGVKHLHDNWILHRD	CDK11A	536	Q9UQ88
ARDHLLHHWIALLAD	DENND5A	1226	Q6IQ26
ALHALNVTWRVRDHH	MAN2B2	331	Q9Y2E5
VIHRTQHWFHGRISR	GRB10	486	Q13322
QHWFHGRISREESHR	GRB10	491	Q13322
HPELWRLTVASHHIR	HERVK_113	336	Q902F9
LSGAHTWRSLIHHIR	C6orf89	91	Q6UWU4
HHHRQLLLEGLARWK	SFI1	781	A8K8P3
TSHLRAHLRWHTGER	SP4	661	Q02446
RLSHLRSEEVHWLHV	PTK2	86	Q05397
LREHVRLVHAHPHWE	WIZ	431	O95785
HRRDGKWQIVHFHRS	CAMK2A	456	Q9UQM7
SHLRAHLRWHTGERP	SP1	641	P08047
ALIHARWDAHRRLQS	PLA2G3	56	Q9NZ20
DIRRFHHSLTDHPRW	SARDH	441	Q9UL12
HHSLTDHPRWIRERS	SARDH	446	Q9UL12
RGELRHIHNLKHWGL	SRPK3	506	Q9UPE1
LIFLLRRWAARHVHH	CNGA3	76	Q16281
RRWAARHVHHQDQGP	CNGA3	81	Q16281
ASLHQWHRRRTLHRK	RINL	526	Q6ZS11
HSRHRSGVELDWVRH	USP42	1021	Q9H9J4
LAHTVRDHLVGRWIR	PYGM	56	P11217
GRWTHQLHGLLLRDR	SOWAHA	321	Q2M3V2
SHLRAHLRWHSGERP	SP3	636	Q02447
HALTPRHLHAWLRGL	REXO5	671	Q96IC2
LAHTVRDHLVGRWIR	PYGB	56	P11216
EFWHRLRVIRTQHHV	MRPL18	76	Q9H0U6
NRTGAEHLWLTRHLR	MRM2	26	Q9UI43
FIQRSHLWGHERIHT	ZNF677	356	Q86XU0
QHWARHRQSGHLLVL	TMEM253	21	P0C7T8
LTRLGRHWLQRLHRA	TMEM245	101	Q9H330
RHWLQRLHRAHTPIV	TMEM245	106	Q9H330
QRHRVRWLHGFAKLH	TEX13A	86	Q9BXU3
AFSWISRLNIHHRIH	ZNF879	436	B4DU55
FRWGAHLVQHQRIHS	ZNF232	341	Q9UNY5
AFTWHSQLARHRRIH	ZNF611	406	Q8N823
AFRWAAGLRHHALTH	ZNF142	1601	P52746
QRLGRALWHLRLAHH	TPGS1	96	Q6ZTW0
ALWHLRLAHHSQRAA	TPGS1	101	Q6ZTW0
LAHTVRDHLVGRWIR	PYGL	56	P06737
IREWRRLPHVVSHVH	TRRAP	2916	Q9Y4A5
REWIRECQHQFRHHR	WNT2B	101	Q93097
RWLVHLRVQHLHTPG	TBC1D2	636	Q9BYX2
RWASTHLTHQRLHSR	ZNF284	521	Q2VY69
RWSSRLLHHQRTHTG	ZNF628	46	Q5EBL2