Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT72 KRT2 KRT4 KRT10 KRT75 KRT71 KRT79

1.39e-1043707GO:0030280
GeneOntologyMolecularFunctionstructural molecule activity

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 NUP214 FLG2 KRT79 ZP2 EMILIN1 NUP153

2.10e-068917014GO:0005198
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNB4 TSPOAP1

4.29e-049702GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNB4 TSPOAP1

4.29e-049702GO:0099626
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNB1 CACNB4 TSPOAP1

5.62e-0446703GO:0005245
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNB1 CACNB4

1.07e-0314702GO:0008331
GeneOntologyMolecularFunctioncalcium channel activity

CACNB1 CACNB4 TSPOAP1 GRIA3

1.10e-03129704GO:0005262
GeneOntologyBiologicalProcessintermediate filament organization

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

4.21e-1275719GO:0045109
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

5.43e-1199719GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

5.95e-11100719GO:0045103
GeneOntologyBiologicalProcesskeratinization

KRT72 KRT2 KRT4 CDSN KRT75 KRT17 KRT71 KRT79

6.18e-1087718GO:0031424
GeneOntologyBiologicalProcesskeratinocyte differentiation

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT79

1.72e-08189719GO:0030216
GeneOntologyBiologicalProcessskin development

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 FLG2 KRT79

5.66e-083737111GO:0043588
GeneOntologyBiologicalProcessepidermis development

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 FLG2 KRT79

4.72e-074617111GO:0008544
GeneOntologyBiologicalProcessepidermal cell differentiation

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT79

5.53e-07284719GO:0009913
GeneOntologyBiologicalProcessepidermis morphogenesis

KRT17 KRT71 KRT28 FLG2

1.89e-0546714GO:0048730
GeneOntologyBiologicalProcesssupramolecular fiber organization

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 NCKAP5 KRT79 EMILIN1 NUP153

2.03e-059577113GO:0097435
GeneOntologyBiologicalProcesskeratinocyte development

KRT2 CDSN KRT10

2.57e-0517713GO:0003334
GeneOntologyBiologicalProcesspositive regulation of meiosis I

EIF4G3 DMRT1

1.16e-045712GO:0060903
GeneOntologyBiologicalProcessepithelial cell differentiation

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 DMRT1 KRT79

1.78e-048707111GO:0030855
GeneOntologyBiologicalProcesshair follicle morphogenesis

KRT17 KRT71 KRT28

3.52e-0440713GO:0031069
GeneOntologyBiologicalProcessregulation of meiosis I

EIF4G3 DMRT1

4.14e-049712GO:0060631
GeneOntologyBiologicalProcessepithelium development

KRT72 KRT2 KRT4 CDSN KRT10 NPHP3 KRT75 KRT17 KRT71 KRT28 KAT2A FLG2 DMRT1 KRT79

4.18e-0414697114GO:0060429
GeneOntologyBiologicalProcesssynaptic signaling

CACNB1 CACNB4 ARID1B SNAP91 TSPOAP1 LZTS1 RNF10 SYN1 DGKI GRIA3 KAT2A

4.77e-049767111GO:0099536
GeneOntologyBiologicalProcesssignal release from synapse

CACNB4 SNAP91 TSPOAP1 SYN1 DGKI

5.63e-04195715GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

CACNB4 SNAP91 TSPOAP1 SYN1 DGKI

5.63e-04195715GO:0007269
GeneOntologyCellularComponentkeratin filament

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT79

1.50e-0997728GO:0045095
GeneOntologyCellularComponentintermediate filament

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

8.42e-08227729GO:0005882
GeneOntologyCellularComponentcornified envelope

KRT2 CDSN KRT10 KRT75 KRT17 FLG2

1.36e-0769726GO:0001533
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

2.94e-07263729GO:0045111
GeneOntologyCellularComponentpostsynaptic density membrane

LZTS1 RNF10 DGKI GRIA3 ELFN2

2.09e-04157725GO:0098839
GeneOntologyCellularComponentextrinsic component of synaptic membrane

SNAP91 RNF10 DGKI

2.37e-0435723GO:0099243
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT72 KRT2 RMDN3 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 NCKAP5 KRT79

2.40e-048997211GO:0099513
GeneOntologyCellularComponentextrinsic component of postsynaptic density membrane

RNF10 DGKI

5.17e-0410722GO:0099147
GeneOntologyCellularComponentpostsynaptic specialization membrane

LZTS1 RNF10 DGKI GRIA3 ELFN2

6.49e-04201725GO:0099634
GeneOntologyCellularComponentextrinsic component of postsynaptic specialization membrane

RNF10 DGKI

7.55e-0412722GO:0098892
GeneOntologyCellularComponentpostsynaptic density

SNAP91 LZTS1 RNF10 SYN1 DGKI GRIA3 ELFN2

9.14e-04451727GO:0014069
GeneOntologyCellularComponentannulate lamellae

RANBP2 NUP153

1.04e-0314722GO:0005642
GeneOntologyCellularComponentasymmetric synapse

SNAP91 LZTS1 RNF10 SYN1 DGKI GRIA3 ELFN2

1.26e-03477727GO:0032279
GeneOntologyCellularComponentpresynaptic active zone

SNAP91 SYN1 DGKI GRIA3

1.43e-03141724GO:0048786
GeneOntologyCellularComponentpostsynaptic specialization

SNAP91 LZTS1 RNF10 SYN1 DGKI GRIA3 ELFN2

1.71e-03503727GO:0099572
GeneOntologyCellularComponentnuclear pore nuclear basket

RANBP2 NUP153

1.73e-0318722GO:0044615
GeneOntologyCellularComponentextrinsic component of presynaptic membrane

SNAP91 DGKI

1.73e-0318722GO:0098888
GeneOntologyCellularComponentneuron to neuron synapse

SNAP91 LZTS1 RNF10 SYN1 DGKI GRIA3 ELFN2

2.13e-03523727GO:0098984
GeneOntologyCellularComponentnuclear inclusion body

RANBP2 NUP153

2.14e-0320722GO:0042405
GeneOntologyCellularComponentsupramolecular fiber

KRT72 KRT2 RMDN3 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 NCKAP5 KRT79

2.23e-0311797211GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT72 KRT2 RMDN3 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 NCKAP5 KRT79

2.35e-0311877211GO:0099081
GeneOntologyCellularComponentclathrin coat of coated pit

EPS15L1 SNAP91

2.35e-0321722GO:0030132
GeneOntologyCellularComponentpresynaptic active zone membrane

SNAP91 DGKI GRIA3

2.48e-0378723GO:0048787
GeneOntologyCellularComponentextrinsic component of postsynaptic membrane

RNF10 DGKI

2.58e-0322722GO:0098890
GeneOntologyCellularComponentpostsynaptic membrane

SNAP91 LZTS1 RNF10 DGKI GRIA3 ELFN2

2.71e-03405726GO:0045211
GeneOntologyCellularComponentpresynapse

CACNB1 EPS15L1 CACNB4 SNAP91 WDR7 TSPOAP1 SYN1 DGKI GRIA3

3.30e-03886729GO:0098793
GeneOntologyCellularComponentaxon

SNAP91 MYCBP2 TSPOAP1 SYN1 DGKI GRIA3 C4B PUM1 ACAP3

3.42e-03891729GO:0030424
GeneOntologyCellularComponentnuclear pore

RANBP2 NUP214 NUP153

5.13e-03101723GO:0005643
GeneOntologyCellularComponentaxon terminus

SNAP91 TSPOAP1 DGKI GRIA3

5.98e-03210724GO:0043679
GeneOntologyCellularComponentexcitatory synapse

SNAP91 DGKI GRIA3

6.02e-03107723GO:0060076
MousePhenoabnormal hair shaft morphology

CDSN KRT75 KRT17 KRT71 PPP1R13L

1.98e-0575625MP:0003809
DomainIF

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

6.90e-1272719PS00226
DomainFilament

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

7.85e-1273719PF00038
DomainIF

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

1.14e-1176719IPR001664
DomainIntermediate_filament_CS

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT79

9.53e-1163718IPR018039
DomainFilament

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

2.55e-1071718SM01391
DomainKeratin_II

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

5.27e-1026716IPR003054
DomainKeratin_2_head

KRT72 KRT2 KRT75 KRT71 KRT79

2.76e-0824715IPR032444
DomainKeratin_2_head

KRT72 KRT2 KRT75 KRT71 KRT79

2.76e-0824715PF16208
DomainKeratin_I

KRT4 KRT10 KRT17 KRT28

2.32e-0544714IPR002957
DomainVDCC_L_bsu

CACNB1 CACNB4

8.51e-054712IPR000584
DomainVGCC_beta4Aa_N

CACNB1 CACNB4

8.51e-054712PF12052
DomainNa/sul_symport

SLC13A4 SLC13A5

1.41e-045712IPR001898
DomainNa_sulph_symp

SLC13A4 SLC13A5

1.41e-045712PF00939
DomainPrefoldin

KRT4 KRT10 KRT75 KRT17

1.62e-0472714IPR009053
Domainzf-RanBP

RANBP2 NUP153

3.13e-0322712PF00641
DomainZnF_RBZ

RANBP2 NUP153

3.42e-0323712SM00547
DomainZF_RANBP2_2

RANBP2 NUP153

3.42e-0323712PS50199
DomainZF_RANBP2_1

RANBP2 NUP153

3.73e-0324712PS01358
DomainZnf_RanBP2

RANBP2 NUP153

4.04e-0325712IPR001876
DomainGuanylate_kin

CACNB1 CACNB4

4.37e-0326712PF00625
DomainGK/Ca_channel_bsu

CACNB1 CACNB4

4.37e-0326712IPR008145
DomainGuanylate_kin-like_dom

CACNB1 CACNB4

4.37e-0326712IPR008144
DomainBromodomain_CS

BAZ2B KAT2A

4.37e-0326712IPR018359
DomainGuKc

CACNB1 CACNB4

4.37e-0326712SM00072
DomainBROMODOMAIN_1

BAZ2B KAT2A

8.71e-0337712PS00633
DomainBromodomain

BAZ2B KAT2A

9.17e-0338712PF00439
DomainKH_1

ANKHD1 NOVA1

9.17e-0338712PF00013
DomainSH3

CACNB1 CACNB4 TSPOAP1 PPP1R13L

9.24e-03216714SM00326
DomainSH3

CACNB1 CACNB4 TSPOAP1 PPP1R13L

9.24e-03216714PS50002
DomainSH3_domain

CACNB1 CACNB4 TSPOAP1 PPP1R13L

9.84e-03220714IPR001452
DomainKH

ANKHD1 NOVA1

1.01e-0240712SM00322
DomainKH_dom

ANKHD1 NOVA1

1.01e-0240712IPR004087
DomainBROMODOMAIN_2

BAZ2B KAT2A

1.06e-0241712PS50014
DomainAnk

DGKI PPP1R13L ANKHD1 ACAP3

1.11e-02228714PF00023
DomainKH_TYPE_1

ANKHD1 NOVA1

1.11e-0242712PS50084
DomainBROMO

BAZ2B KAT2A

1.11e-0242712SM00297
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

1.10e-12875510MM15351
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

5.97e-111295510M27649
PathwayREACTOME_KERATINIZATION

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

3.25e-101535510MM15343
PathwayREACTOME_KERATINIZATION

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

9.70e-092175510M27640
PathwayBIOCARTA_NPC_PATHWAY

RANBP2 NUP214 NUP153

9.07e-0611553M22033
PathwayREACTOME_GLUCOSE_METABOLISM

SLC37A1 RANBP2 NUP214 PFKFB3 NUP153

1.63e-0582555MM15394
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RANBP2 TNRC6A NUP214 NUP153

1.89e-0541554MM15200
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

KRT72 KRT2 KRT4 CACNB1 CDSN CACNB4 KRT10 ARID1B KRT75 KRT17 KRT71 KRT28 TNRC6A KAT2A DMRT1 KRT79 ZP2

1.89e-0514325517M509
PathwayREACTOME_GLUCOSE_METABOLISM

SLC37A1 RANBP2 NUP214 PFKFB3 NUP153

1.94e-0585555M1870
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

KRT72 KRT2 KRT4 CDSN KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

2.07e-055025510MM14537
PathwayREACTOME_GENE_SILENCING_BY_RNA

RANBP2 TNRC6A NUP214 NUP153

3.86e-0549554MM14837
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A4 SLC13A5

1.48e-045552MM15099
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A4 SLC13A5

1.48e-045552M27354
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

RANBP2 NUP214 EIF4G3 NUP153

1.95e-0474554M48006
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

RANBP2 NUP214 NUP153

2.57e-0432553M29579
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

RANBP2 NUP214 NUP153

2.82e-0433553M27016
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

RANBP2 NUP214 NUP153

3.09e-0434553M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RANBP2 NUP214 NUP153

3.37e-0435553M27320
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RANBP2 NUP214 NUP153

3.66e-0436553M27245
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RANBP2 NUP214 NUP153

3.66e-0436553M26974
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

RANBP2 NUP214 NUP153

3.98e-0437553M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

RANBP2 NUP214 NUP153

3.98e-0437553M27038
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RANBP2 NUP214 NUP153

4.65e-0439553M27238
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RANBP2 NUP214 NUP153

5.01e-0440553MM14945
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

RANBP2 NUP214 NUP153

5.39e-0441553M29574
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RANBP2 NUP214 NUP153

5.79e-0442553MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RANBP2 NUP214 NUP153

6.21e-0443553MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RANBP2 NUP214 NUP153

6.21e-0443553M26975
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

RANBP2 NUP214 NUP153

6.65e-0444553M109
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RANBP2 NUP214 NUP153

7.58e-0446553M27397
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RANBP2 TNRC6A NUP214 NUP153

7.67e-04106554M27458
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNB1 CACNB4

8.04e-0411552MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNB1 CACNB4

8.04e-0411552M26913
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RANBP2 NUP214 NUP153

8.07e-0447553MM14939
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RANBP2 NUP214 NUP153

8.07e-0447553M27395
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RANBP2 NUP214 NUP153

9.67e-0450553MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RANBP2 NUP214 NUP153

1.03e-0351553MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RANBP2 NUP214 NUP153

1.15e-0353553M27212
PathwayREACTOME_SNRNP_ASSEMBLY

RANBP2 NUP214 NUP153

1.21e-0354553M29594
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RANBP2 NUP214 NUP153

1.28e-0355553MM14917
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNB1 CACNB4 TSPOAP1 SYN1 GRIA3

1.36e-03211555MM14502
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RANBP2 NUP214 NUP153

1.49e-0358553MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RANBP2 NUP214 NUP153

1.49e-0358553MM14736
PathwayREACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

RANBP2 NUP214 NUP153

1.57e-0359553M27606
PathwayPID_SMAD2_3PATHWAY

NUP214 NUP153

1.73e-0316552M228
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RANBP2 NUP214 NUP153

2.07e-0365553MM15147
PathwayREACTOME_GENE_SILENCING_BY_RNA

RANBP2 TNRC6A NUP214 NUP153

2.09e-03139554M715
PathwayPID_HDAC_CLASSI_PATHWAY

RANBP2 MAX SMG5

2.16e-0366553M101
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

TSPOAP1 SYN1

2.20e-0318552MM14702
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

TSPOAP1 SYN1

2.20e-0318552M27043
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RANBP2 NUP214 NUP153

2.66e-0371553M27394
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

RANBP2 NUP214 EIF4G3 NUP153

2.82e-03151554M550
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RANBP2 NUP214 NUP153

2.88e-0373553MM14948
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

CACNB1 CACNB4 GRIA3

2.88e-0373553MM16641
PathwayKEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING

CACNB1 CACNB4

2.99e-0321552M47950
PathwayKEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING

CACNB1 CACNB4

2.99e-0321552M47949
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RANBP2 NUP214 NUP153

3.35e-0377553M27226
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

TSPOAP1 SYN1

3.59e-0323552MM14852
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

TSPOAP1 SYN1

3.59e-0323552M12627
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNB1 CACNB4 TSPOAP1 SYN1 GRIA3

3.96e-03270555M15514
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RANBP2 NUP214 NUP153

4.00e-0382553M27250
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

SLC37A1 RANBP2 NUP214 PFKFB3 NUP153

4.02e-03271555MM15406
PathwayPID_MYC_PATHWAY

MAX KAT2A

4.23e-0325552M139
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNB1 CACNB4

4.23e-0325552M47948
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RANBP2 NUP214 NUP153

4.28e-0384553MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RANBP2 NUP214 NUP153

4.28e-0384553M725
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RANBP2 NUP214 NUP153

4.58e-0386553MM15413
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

SLC37A1 RANBP2 NUP214 PFKFB3 NUP153

5.19e-03288555M16864
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RANBP2 NUP214 NUP153

5.52e-0392553MM14951
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA

RANBP2 NUP214

6.06e-0330552M47752
Pubmed

New consensus nomenclature for mammalian keratins.

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

9.00e-156372916831889
Pubmed

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

2.94e-115772731862882
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

RANBP2 ARID1B MUC19 NUP214 EIF4G3 NUP153 PDZD2

7.09e-0912372726912792
Pubmed

Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.

KRT2 KRT4 KRT75 KRT71

3.01e-081672412399393
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SPATC1 KRT72 KRT2 RANBP2 KRT10 KRT75 KRT17 KRT71 SNAP91 SBNO1 SETD5 TRO GRIA3 KAT2A EIF4G3 KRT79

3.22e-081442721635575683
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNB1 EPS15L1 CACNB4 SNAP91 MYCBP2 WDR7 SYN1 EIF4G3 ELFN2

4.33e-0834772917114649
Pubmed

A giant nucleopore protein that binds Ran/TC4.

RANBP2 NUP214 NUP153

8.48e-0857237603572
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

RANBP2 NUP214 NUP153

8.48e-08572316730000
Pubmed

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains.

RANBP2 NUP214 NUP153

8.48e-08572312138183
Pubmed

Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.

KRT10 KRT75 KRT17 KRT79

9.84e-082172424198274
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

KRT72 KRT2 KRT10 KRT17 FLG2 KRT79

3.87e-0713572629859926
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

RANBP2 NUP214 NUP153

4.73e-07872331375530
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNB1 RANBP2 EPS15L1 CACNB4 SNAP91 MYCBP2 WDR7 LZTS1 SYN1 DGKI GRIA3 NUP153

6.33e-07963721228671696
Pubmed

Cloning and characterization of human karyopherin beta3.

RANBP2 NUP214 NUP153

7.08e-0797239114010
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

LENG8 MYCBP2 SBNO1 TNRC6A NUP214 EIF4G3 ANKHD1

7.26e-0724272734011540
Pubmed

A human MAP kinase interactome.

LENG8 RMDN3 RANBP2 KRT17 MAX TNRC6A NCKAP5 NUP214 NUP153

7.36e-0748672920936779
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

KRT2 KRT4 KRT10 KRT17 FLG2

8.98e-078472529563501
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KRT72 KRT2 GJA3 EPS15L1 CACNB4 KRT10 SNAP91 WDR7 LZTS1 SYN1 C4B EIF4G3 KRT79 ELFN2

1.19e-061431721437142655
Pubmed

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.

KRT2 KRT4 KRT10 KRT17 FLG2

1.34e-069172534445801
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WDR7 TSPOAP1 SETD5 TRO NUP214 PUM1 PLCE1 PDZD2

2.04e-0640772812693553
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

KRT72 KRT2 KRT4 CDSN KRT10 KRT17 KRT71 PFKFB3 FLG2

2.29e-0655872927591049
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

KRT72 KRT2 KRT4 KRT10 NPHP3 KRT17 FLG2 ANKHD1 KRT79

2.50e-0656472921565611
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNB1 RANBP2 EPS15L1 CACNB4 PLAA MYCBP2 TSPOAP1 TNRC6A RNF10 GRIA3 EIF4G3 ELFN2

3.61e-061139721236417873
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RANBP2 NUP214 NUP153

3.80e-061572314697343
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

KRT2 RANBP2 KRT75 MYCBP2 EIF4G3 KRT79

4.05e-0620272624639526
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

KRT72 KRT2 KRT4 KRT10 ARID1B KRT75 KRT17 KRT71 KRT28 PIN4 KRT79 NUP153

4.08e-061153721229845934
Pubmed

Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.

KRT2 KRT10

4.23e-06272224751727
Pubmed

Keratin K6irs is specific to the inner root sheath of hair follicles in mice and humans.

KRT72 KRT71

4.23e-06272211703281
Pubmed

Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.

CACNB1 CACNB4

4.23e-06272214500989
Pubmed

Out of balance: consequences of a partial keratin 10 knockout.

KRT2 KRT10

4.23e-0627229378767
Pubmed

Acute necrotizing encephalopathy-linked mutations in Nup358 impair interaction of Nup358 with TNRC6/GW182 and miRNA function.

RANBP2 TNRC6A

4.23e-06272233962210
Pubmed

Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.

KRT2 KRT10

4.23e-06272226603179
Pubmed

Knockdown screens to knockout HIV-1.

RANBP2 NUP153

4.23e-06272218984154
Pubmed

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.

KRT2 KRT10 KRT17 FLG2

4.94e-065472435474131
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

LENG8 MYCBP2 TNRC6A UCK2 NUP214 SMG5 KAT2A EIF4G3

5.19e-0646272831138677
Pubmed

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

RANBP2 NUP214 NUP153

5.67e-061772310668806
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

KRT2 CDSN KRT10 KRT75 KRT17 FLG2 PPP1R13L PUM1

7.74e-0648872831324722
Pubmed

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

KRT10 KRT75 KRT17 FLG2

8.60e-066272426644517
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

CACNB1 RANBP2 EPS15L1 CACNB4 SYN1 ELFN2

8.72e-0623172616452087
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RANBP2 KRT10 ARID1B NPHP3 KRT17 MYCBP2 RNF10 PLCE1

8.83e-0649772823414517
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

KRT2 CDSN KRT10 KRT75 KRT17 FLG2

1.03e-0523872635864588
Pubmed

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.

KRT10 KRT75 KRT71

1.10e-052172322935613
Pubmed

Basal cytokeratin expression in relation to immunohistochemical and clinical characterization in breast cancer patients with triple negative phenotype.

KRT75 KRT17

1.27e-05372219366057
Pubmed

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.

NUP214 NUP153

1.27e-05372212191473
Pubmed

Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors.

RANBP2 NUP153

1.27e-05372223883001
Pubmed

Ozone therapy promotes the differentiation of basal keratinocytes via increasing Tp63-mediated transcription of KRT10 to improve psoriasis.

KRT72 KRT10

1.27e-05372232168425
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP214 NUP153

1.27e-0537229847314
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP214 NUP153

1.27e-05372221327100
Pubmed

Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.

KRT2 KRT10

1.27e-05372226581228
Pubmed

Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.

CACNB1 CACNB4

1.27e-05372222737983
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

RANBP2 NUP214 NUP153

1.89e-052572310601273
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

KRT2 KRT4 KRT10 KRT75 KRT17 KRT79

1.94e-0526672619380743
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

RANBP2 NUP214 NUP153 PDZD2

2.04e-057772424927568
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

RANBP2 NUP214 NUP153

2.14e-052672312228227
Pubmed

Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

KRT71 KRT28

2.53e-05472217920809
Pubmed

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).

CACNB1 CACNB4

2.53e-05472216636205
Pubmed

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

RANBP2 NUP153

2.53e-05472222174692
Pubmed

Using transgenic models to study the pathogenesis of keratin-based inherited skin diseases.

KRT4 KRT10

2.53e-05472210511477
Pubmed

Mutations of calcium channel beta subunit genes in mice.

CACNB1 CACNB4

2.53e-05472210494839
Pubmed

K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle.

KRT72 KRT71

2.53e-05472212648212
Pubmed

Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.

CACNB1 CACNB4

2.53e-05472219996312
Pubmed

Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export.

RANBP2 NUP153

2.53e-05472211839768
Pubmed

Protein-protein interactions between keratin polypeptides expressed in the yeast two-hybrid system.

KRT72 KRT17

2.53e-0547229630597
Pubmed

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments.

KRT10 KRT17

2.53e-0547226188955
Pubmed

Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes.

KRT2 KRT10

2.53e-05472232179842
Pubmed

Molecular mechanisms of retroviral integration site selection.

RANBP2 NUP153

2.53e-05472225147212
Pubmed

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.

KRT2 KRT10 KRT75 KRT71 PFKFB3

2.75e-0516972523084401
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

KRT72 KRT2 KRT10 KRT17 FLG2 ANKHD1

2.91e-0528672632041737
Pubmed

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR.

KRT2 KRT10 KRT17 TNRC6A C4B FLG2

3.08e-0528972637132043
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

RANBP2 NUP214 NUP153

3.32e-053072324315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

RANBP2 NUP214 NUP153

3.32e-053072327016207
Pubmed

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.

CDSN KRT10 FLG2

3.32e-053072334905516
Pubmed

Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.

RANBP2 FLG2 PPP1R13L PUM1

3.61e-058972431267705
Pubmed

Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

CACNB1 CACNB4

4.21e-05572219723630
Pubmed

Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation.

MAX KAT2A

4.21e-05572220691906
Pubmed

RanGTP mediates nuclear pore complex assembly.

RANBP2 NUP153

4.21e-05572212894213
Pubmed

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

NUP214 NUP153

4.21e-05572212917407
Pubmed

A model for cofactor use during HIV-1 reverse transcription and nuclear entry.

RANBP2 NUP153

4.21e-05572224525292
Pubmed

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases.

CACNB1 CACNB4

4.21e-05572214623965
Pubmed

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.

NUP214 NUP153

4.21e-05572211777942
Pubmed

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc.

MAX KAT2A

4.21e-05572210611234
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

RANBP2 NUP214

4.21e-05572219828735
Pubmed

Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.

CACNB1 CACNB4

4.21e-05572211980879
Pubmed

Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors.

MAX KAT2A

4.21e-05572222086303
Pubmed

HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.

RANBP2 NUP153

4.21e-05572226109731
Pubmed

Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters.

SLC13A4 SLC13A5

4.21e-05572216211368
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

LENG8 ARID1B TNRC6A NUP214 ANKHD1 PUM1 NUP153

4.56e-0545772732344865
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

NUP214 OLIG2 NUP153

4.86e-053472318539113
Pubmed

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

KRT2 MAX KAT2A

5.31e-053572320946988
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

KRT2 RANBP2 KRT10 PLAA KRT17 FLG2 ANKHD1 NUP153

5.41e-0564172836057605
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

KRT2 RANBP2 TNRC6A NUP214 PPP1R13L ANKHD1 PUM1 NUP153

6.29e-0565572835819319
Pubmed

Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development.

KRT10 KRT17

6.31e-0567229786956
Pubmed

Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development.

KRT4 KRT10

6.31e-05672215944823
Pubmed

Development, structure, and keratin expression in C57BL/6J mouse eccrine glands.

KRT10 KRT17

6.31e-05672222135020
Pubmed

Karyopherin beta2 mediates nuclear import of a mRNA binding protein.

RANBP2 NUP214

6.31e-0567229144189
Pubmed

beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.

CACNB1 CACNB4

6.31e-05672210328888
Pubmed

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.

RANBP2 NUP153

6.31e-05672211266456
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BAZ2B PHF12 TNRC6A PLCE1

6.39e-0510372410819331
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RANBP2 NUP214 NUP153

6.81e-053872312791264
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

RMDN3 RANBP2 TRO MAX PANK4 SMG5 ANKHD1 PUM1 NOVA1

6.82e-0585772925609649
InteractionKRT84 interactions

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 KRT79

3.43e-1049707int:KRT84
InteractionKRT28 interactions

KRT72 KRT2 KRT4 KRT71 KRT28 KRT79

7.84e-1030706int:KRT28
InteractionKRT25 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

2.11e-0935706int:KRT25
InteractionRNF208 interactions

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

7.38e-0975707int:RNF208
InteractionKRT5 interactions

KRT72 KRT2 KRT10 NPHP3 KRT75 KRT17 KRT71 KRT28 KRT79

2.21e-08193709int:KRT5
InteractionKRT24 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

3.20e-0854706int:KRT24
InteractionKRT6A interactions

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 KRT28 KRT79

8.23e-08160708int:KRT6A
InteractionKRT26 interactions

KRT72 KRT4 KRT75 KRT71 KRT79

1.31e-0735705int:KRT26
InteractionKRT13 interactions

KRT72 KRT2 KRT4 KRT75 KRT17 KRT71 KRT79

1.55e-07116707int:KRT13
InteractionKRT36 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

2.17e-0774706int:KRT36
InteractionKRT16 interactions

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 KRT79

4.06e-07197708int:KRT16
InteractionKRT19 interactions

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 TNRC6A KRT79

5.58e-07282709int:KRT19
InteractionKRT33B interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

8.48e-0793706int:KRT33B
InteractionEPS15 interactions

KRT2 KRT4 EPS15L1 KRT10 KRT75 KRT17 SNAP91 KRT79

9.37e-07220708int:EPS15
InteractionKRT37 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

1.30e-06100706int:KRT37
InteractionKRT35 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

2.40e-06111706int:KRT35
InteractionKRT8 interactions

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 KRT28 TNRC6A PUM1 KRT79

2.79e-064417010int:KRT8
InteractionKRT75 interactions

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 KRT79

3.12e-06181707int:KRT75
InteractionKRT27 interactions

KRT72 KRT2 KRT4 KRT75 KRT17 KRT71 KRT79

6.44e-06202707int:KRT27
InteractionPRPH interactions

KRT72 KRT2 KRT10 KRT75 KRT17 KRT71 TNRC6A

6.86e-06204707int:PRPH
InteractionCYLD interactions

KRT72 KRT2 KRT4 EPS15L1 CDSN KRT10 KRT17 KRT71 TNRC6A MUC19 NUP214 PFKFB3 FLG2

7.81e-068687013int:CYLD
InteractionKRT7 interactions

KRT72 KRT2 KRT10 KRT75 KRT17

8.59e-0680705int:KRT7
InteractionKRT18 interactions

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 TNRC6A KRT79

1.41e-05419709int:KRT18
InteractionNUP35 interactions

LENG8 RANBP2 ARID1B TNRC6A NUP214 ANKHD1 PUM1 NUP153 PDZD2

1.55e-05424709int:NUP35
InteractionKRT2 interactions

KRT2 KRT10 NPHP3 KRT75 KRT17 KRT28 KAT2A

1.77e-05236707int:KRT2
InteractionKRT77 interactions

KRT2 KRT10 NPHP3 KRT75 KRT17

2.09e-0596705int:KRT77
InteractionKRT17 interactions

KRT72 KRT2 KRT10 KRT75 KRT17 FLG2 KRT79

2.70e-05252707int:KRT17
InteractionKRT38 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

2.95e-05172706int:KRT38
InteractionCUL2 interactions

KRT2 RANBP2 KRT10 ARID1B KRT75 KRT71 NUP214 KAT2A PFKFB3 FLG2

3.55e-055917010int:CUL2
InteractionKRT15 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

3.58e-05178706int:KRT15
InteractionKRT72 interactions

KRT72 KRT75 KRT17 KRT28

5.26e-0559704int:KRT72
InteractionKRT79 interactions

KRT75 KRT17 KRT28 KRT79

5.26e-0559704int:KRT79
InteractionKRT14 interactions

KRT72 KRT2 KRT4 KRT75 KRT17 KRT79

5.46e-05192706int:KRT14
InteractionKRT20 interactions

KRT72 KRT2 KRT75 KRT79

6.81e-0563704int:KRT20
InteractionAP2M1 interactions

KRT2 EPS15L1 KRT10 KRT17 SNAP91 TNRC6A DGKI KRT79

1.19e-04430708int:AP2M1
InteractionKRT40 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 SETD5 LRCH4 KRT79

1.27e-04434708int:KRT40
InteractionARG1 interactions

CDSN KRT17 MAX POC1B FLG2

1.70e-04149705int:ARG1
InteractionKRT1 interactions

KRT2 KRT10 NPHP3 KRT75 KRT17 KRT28

1.78e-04238706int:KRT1
InteractionPHF21A interactions

RANBP2 MYCBP2 PHF12 MAX TNRC6A NUP214 ANKHD1

1.86e-04343707int:PHF21A
InteractionKRT76 interactions

KRT10 KRT75 KRT17 KRT28

2.09e-0484704int:KRT76
InteractionUBASH3B interactions

KRT2 KRT4 KRT10 KRT17 KRT79

2.17e-04157705int:UBASH3B
InteractionDES interactions

KRT72 KRT2 KRT10 KRT75 KRT17

2.23e-04158705int:DES
InteractionCACNA1B interactions

CACNB1 CACNB4 WDR7

2.87e-0437703int:CACNA1B
InteractionHEXIM1 interactions

KRT72 KRT2 KRT4 KRT10 ARID1B KRT75 KRT17 KRT71 KRT28 PIN4 KRT79

2.90e-049137011int:HEXIM1
InteractionLGR4 interactions

KRT2 RANBP2 KRT75 MYCBP2 EIF4G3 KRT79

2.98e-04262706int:LGR4
InteractionNUP43 interactions

RANBP2 ARID1B BAZ2B PHF12 MUC19 NUP214 EIF4G3 NUP153 PDZD2

3.02e-04625709int:NUP43
InteractionZUP1 interactions

KRT2 KRT4 KRT10 KRT17 FLG2

3.48e-04174705int:ZUP1
InteractionTNIK interactions

CACNB1 CACNB4 SNAP91 MYCBP2 LZTS1 DGKI GRIA3

3.52e-04381707int:TNIK
InteractionKDM1A interactions

LENG8 RANBP2 KRT17 MYCBP2 LZTS1 PHF12 MAX TNRC6A RNF10 NUP214 ANKHD1

3.75e-049417011int:KDM1A
InteractionBTG3 interactions

MYCBP2 TNRC6A RNF10 SMG5

3.77e-0498704int:BTG3
InteractionNPHP3 interactions

KRT2 KRT10 NPHP3

4.18e-0442703int:NPHP3
InteractionKRT71 interactions

KRT75 KRT71 KRT28

4.48e-0443703int:KRT71
InteractionKRT34 interactions

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

4.49e-04283706int:KRT34
InteractionKRT32 interactions

KRT72 KRT2 KRT75

4.80e-0444703int:KRT32
InteractionKRT10 interactions

KRT2 KRT10 NPHP3 KRT75 KRT17

4.84e-04187705int:KRT10
InteractionFOXP3 interactions

LENG8 RANBP2 MAX NUP214 PFKFB3 EIF4G3 NOVA1

7.42e-04432707int:FOXP3
InteractionUNC79 interactions

MYCBP2 ELFN2

7.67e-0412702int:UNC79
InteractionREM1 interactions

CACNB1 CACNB4

7.67e-0412702int:REM1
Cytoband12q13.13

KRT72 KRT2 KRT4 KRT71 KRT79

7.38e-086772512q13.13
CytobandEnsembl 112 genes in cytogenetic band chr12q13

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

5.52e-05423726chr12q13
Cytoband10q23

KLLN PLCE1

1.87e-041372210q23
GeneFamilyKeratins, type II

KRT72 KRT2 KRT4 KRT75 KRT71 KRT79

1.19e-1027526609
GeneFamilyKeratins, type I

KRT10 KRT17 KRT28

6.99e-0528523608
GeneFamilyNucleoporins

RANBP2 NUP214 NUP153

1.05e-04325231051
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 NUP153

1.65e-032152289
GeneFamilyCalcium voltage-gated channel subunits

CACNB1 CACNB4

2.52e-0326522253
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

CACNB1 CACNB4

2.52e-0326522904
GeneFamilyAnkyrin repeat domain containing

DGKI PPP1R13L ANKHD1 ACAP3

5.13e-03242524403
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRT72 CDSN KRT10 KRT75 KRT17 KRT71 KRT79 IRX4

2.56e-08173728M650
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRT72 CDSN KRT10 KRT75 KRT17 KRT71 KRT79 IRX4

9.17e-08204728MM966
CoexpressionMARTINEZ_TP53_TARGETS_DN

KRT72 KRT75 KRT17 KRT71 TRO MAX TNRC6A PFKFB3 KRT79 IRX4

6.82e-066157210M8673
CoexpressionMARTINEZ_TP53_TARGETS_DN

KRT72 KRT75 KRT17 KRT71 TRO MAX TNRC6A PFKFB3 KRT79 IRX4

1.24e-056597210MM1040
CoexpressionGSE23695_CD57_POS_VS_NEG_NK_CELL_UP

RANBP2 EPS15L1 MYCBP2 PFKFB3 EIF4G3 ANKHD1

1.83e-05199726M7784
CoexpressionGSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP

KRT2 GJA3 CES5A BAZ2B TNRC6A DGKI

1.83e-05199726M4886
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

KRT72 KRT75 KRT17 KRT71 TRO MAX TNRC6A KRT79 IRX4

4.36e-05610729M3854
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

KRT72 KRT75 KRT17 KRT71 TRO MAX TNRC6A KRT79 IRX4

7.10e-05650729MM1042
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

CDSN KRT10 KRT75 KRT17 FLG2 IRX4

5.92e-071877262ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT4 CACNB4 PFKFB3 PPP1R13L NUP153

1.01e-05177725a235ff4f37a7622216526191efc4832fb8ed6957
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LZTS1 DGKI NCKAP5 PLCE1 PDZD2

1.03e-05178725185b44700f06ec58b3c09c80520502166c965fd6
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

CACNB4 KRT17 LZTS1 NCKAP5 IRX4

1.12e-0518172533938e6521712058312879f84f4ae381c2bfc379
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT4 KRT75 CES5A KRT79

1.33e-0589724606fbee8326e55fed7b1fd96d3ae80c0b0cfa3c8
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Acta2_(Mural.Rgs5Acta2.Acta2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT4 KRT75 CES5A KRT79

1.33e-0589724018ea3fd99eca755c1656c08b35d48e5085788d1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Acta2_(Mural.Rgs5Acta2.Acta2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT4 KRT75 CES5A KRT79

1.33e-0589724eeafa9e27d0d22242a2f91774ae78df104337696
ToppCellTCGA-Skin-Primary_Tumor|TCGA-Skin / Sample_Type by Project: Shred V9

CDSN KRT10 KRT75 KRT17 FLG2

1.42e-05190725e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCellTCGA-Skin-Primary_Tumor-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

CDSN KRT10 KRT75 KRT17 FLG2

1.42e-0519072501fb45add4661bc86cd0a34fac35177907152dbb
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

CDSN KRT10 KRT75 KRT17 FLG2

1.42e-051907253188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LENG8 LZTS1 KAT2A EMILIN1 ACAP3

1.65e-05196725b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-052007254fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-05200725f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-05200725cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-05200725310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-05200725c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

DGKI GRIA3 ELFN2 NOVA1 PDZD2

1.81e-05200725961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfacs-Thymus-nan-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CES5A FLG2 OLIG2 LRRC74B

7.84e-05140724115bd770a9d5e6f007a9aa0eadf5dba46d500107
ToppCellfacs-Thymus-nan-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CES5A FLG2 OLIG2 LRRC74B

7.84e-0514072422d126e80bf7d9c0ca6ec686b5cc66fa584a1ab6
ToppCellfacs-Thymus-nan-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CES5A FLG2 OLIG2 LRRC74B

7.84e-0514072462d1ef8cb78618ed89cac7ec89d7f54de06a90c7
ToppCellClub_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

KRT4 KRT17 TRO GREB1

1.31e-04160724b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

SLC13A4 SYN1 UCK2 EMILIN1

1.34e-0416172451b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 SYN1 EMILIN1 PLCE1

1.38e-04162724c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 SYN1 EMILIN1 PLCE1

1.38e-04162724f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 SYN1 EMILIN1 PLCE1

1.38e-041627245d902bb31e691aea9749617cc88303c2448f24b8
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 CACNB1 PANK4 GREB1

1.69e-04171724a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCellTuft-tuft-4|World / Class top

CACNB4 WDR7 DGKI PFKFB3

1.81e-04174724d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DGKI NCKAP5 EMILIN1 NOVA1

1.85e-04175724a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

RANBP2 UCK2 PFKFB3 ANKHD1

1.89e-04176724476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellAT1-AT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CDSN KRT17 LRCH4 NCKAP5

1.89e-04176724f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT75 KRT17 PPP1R13L IRX4

2.11e-04181724a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT75 KRT17 PPP1R13L IRX4

2.11e-04181724504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT75 KRT17 PPP1R13L IRX4

2.11e-04181724a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.20e-0418372424db9cc717e651586317c6a8e03a3401651273c1
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.20e-0418372492ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT10 KRT17 PPP1R13L KRT79

2.29e-04185724657fd191ed160f8620d57b33820ec7222806f289
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

LZTS1 EMILIN1 PLCE1 PDZD2

2.34e-04186724c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCelldroplet-Marrow-nan-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.38e-04187724f491ec986dd44e2dabdf4a75c3101e3b6c921872
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRO C4B GREB1 PLCE1

2.38e-041877246f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCKAP5 OLIG2 NOVA1 PDZD2

2.38e-04187724daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCelldroplet-Marrow-nan-24m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.38e-0418772496dc5dc4dbc1b33c2e66666e9027cfbf7972090b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCKAP5 OLIG2 NOVA1 PDZD2

2.38e-041877245b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 OLIG2 ELFN2 ACAP3

2.43e-04188724a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCelldroplet-Marrow-nan-21m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.43e-041887247c67330c36696a7772364af67c6df4e6406fa742
ToppCelldroplet-Marrow-nan-21m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UCK2 GRIA3 KAT2A EMILIN1

2.43e-04188724f94dc08948a823f47882aa0714b9a60de4ff85d5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 OLIG2 ELFN2 ACAP3

2.43e-04188724c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CDSN NCKAP5 PLCE1 PDZD2

2.48e-041897245a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 OLIG2 ELFN2 NOVA1

2.58e-04191724ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA3 OLIG2 ELFN2 NOVA1

2.58e-04191724478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1B TNRC6A GREB1 PUM1

2.64e-04192724916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ARID1B TNRC6A NCKAP5 PDZD2

2.64e-04192724e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARID1B DGKI EIF4G3 ANKHD1

2.69e-04193724779276e775cb2492e8dd36436295a536084a6415
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1B SETD5 TNRC6A PUM1

2.69e-04193724e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

LZTS1 NCKAP5 PLCE1 PDZD2

2.74e-041947243892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 CACNB4 TRO GREB1

2.80e-04195724d32716a12014522492becbde1088dc1106308490
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 CACNB4 TRO GREB1

2.80e-04195724b913d5df50c88a3a255f516a1aa42419c6701e1e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNAP91 LZTS1 TRO SYN1

2.80e-04195724ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIA3 OLIG2 ELFN2 PDZD2

2.85e-04196724671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNB4 SNAP91 TRO SYN1

2.85e-04196724de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCellfacs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 UCK2 GRIA3 EMILIN1

2.85e-04196724c5adc95df9e1d1884a7988336e459a98c5a6769b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNB4 SNAP91 DGKI GRIA3

2.85e-04196724676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIA3 OLIG2 ELFN2 PDZD2

2.85e-04196724f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCellfacs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 UCK2 GRIA3 EMILIN1

2.85e-0419672481d1fd63397b2cf893607d828b61a926fa65185f
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega|Control_saline / Treatment groups by lineage, cell group, cell type

SLC13A4 POC1B RNF10 KRT79

2.96e-041987241a39a98beef68e1e6d3adc25270a3336fcc5baf4
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

SLC13A4 POC1B RNF10 KRT79

2.96e-04198724dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC13A4 SNAP91 SLC13A5 ZP2

2.96e-04198724b6fea363463c8dd7e6780c085ece4900266a6286
ToppCellSigmoid-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

PLAA BAZ2B DMRT1 ANKHD1

2.96e-04198724305d7ae9b070ac7211638a5282374c02bf13af40
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNB4 SNAP91 DGKI GRIA3

2.96e-041987246d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellControl_saline-Hematopoietic_Erythro-Megakary|Control_saline / Treatment groups by lineage, cell group, cell type

SLC13A4 POC1B RNF10 KRT79

2.96e-04198724cfc2a860bae883299987d3e374d0476ca20e1bdd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNB4 SNAP91 DGKI GRIA3

2.96e-041987244ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellBiopsy_Control_(H.)-Epithelial-Basal|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KRT4 KRT17 DGKI PPP1R13L

3.02e-041997246a274a5db02c55bbf31d602b9d5c8394241acdca
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

KRT2 KRT10 MYCBP2 PPP1R13L

3.02e-041997246be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B BAZ2B TNRC6A EIF4G3

3.02e-0419972494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

CACNB4 MYCBP2 SBNO1 SYN1

3.08e-04200724c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LZTS1 NCKAP5 PLCE1 PDZD2

3.08e-042007240c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LZTS1 NCKAP5 PLCE1 PDZD2

3.08e-0420072494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNB4 SNAP91 MYCBP2 DGKI

3.08e-0420072448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KRT4 CACNB4 KRT17 PPP1R13L

3.08e-04200724d536180a308abc5703d5c8bb33dfe57dc4cc6577
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LZTS1 NCKAP5 PLCE1 PDZD2

3.08e-04200724522a51a284d2992d519c4669e1a48c8ebcc08c80
ComputationalGenes in the cancer module 68.

KRT2 KRT4 KRT17

1.45e-0426433MODULE_68
ComputationalKeratin.

KRT2 KRT4 KRT17

1.45e-0426433MODULE_298
Drugteleocidin B

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

1.25e-07123727CID000072425
Drugsulfur mustard

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

1.82e-07130727CID000010461
Drughomocysteine thiolactone

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

1.92e-07131727CID000107712
Drugal-Badry

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71

9.16e-07165727CID000004545
Drugdithranol

KRT2 KRT10 KRT75

2.39e-0518723CID000002202
Drugadenosine 3',5'-cyclic phosphate

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 KRT71 MYCBP2 PIN4 SYN1 PFKFB3 PLCE1

2.52e-059077212CID000000274
DrugAC1L9MJT

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17

3.27e-05192726CID000448959
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; HL60; HG-U133A

RANBP2 EPS15L1 BAZ2B NUP214 PFKFB3 PUM1

3.57e-051957261979_DN
Drug1-2q

KRT72 KRT2 KRT4 KRT10 KRT75 KRT17 LZTS1

3.59e-05289727CID000011820
DrugPapaverine hydrochloride [61-25-6]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PLAA MAX SMG5 KAT2A PPP1R13L PUM1

3.67e-051967266245_DN
DrugMK-6

KRT4 KRT75 TNRC6A

5.85e-0524723CID005283547
Diseaseinsulin sensitivity measurement, glucose homeostasis measurement

KRT10 SETD5 KRT28 PLCE1

3.54e-0643714EFO_0004471, EFO_0006896
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A4 SLC13A5

5.68e-055712DOID:0111668 (implicated_via_orthology)
DiseasePachyonychia Congenita

KRT10 KRT17

5.68e-055712C0265334
Diseasepeeling skin syndrome (is_implicated_in)

CDSN FLG2

8.51e-056712DOID:0060283 (is_implicated_in)
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A4 SLC13A5

1.58e-048712DOID:0050667 (implicated_via_orthology)
DiseasePosterior subcapsular cataract

GJA3 PANK4

1.58e-048712C0858617
Diseasereaction time measurement

KRT17 SNAP91 WDR7 MUC19 DGKI NCKAP5 EIF4G3 ELFN2

1.81e-04658718EFO_0008393
Diseaseselective IgA deficiency disease

NCKAP5 PFKFB3 DMRT1

1.88e-0446713EFO_1001929
Diseasecortical thickness

ARID1B SNAP91 MYCBP2 SETD5 TNRC6A DGKI NCKAP5 EIF4G3 PLCE1 PDZD2

3.20e-0411137110EFO_0004840
DiseaseRenal dysplasia and retinal aplasia (disorder)

NPHP3 POC1B

3.71e-0412712C0403553
Diseasebrain disease (is_implicated_in)

RANBP2 NUP214

3.71e-0412712DOID:936 (is_implicated_in)
DiseaseContact Dermatitis

KRT2 KRT4 KRT10

6.79e-0471713C0011616
DiseaseContact hypersensitivity

KRT2 KRT4 KRT10

6.79e-0471713C0162351
Diseasepreeclampsia

MYCBP2 LZTS1 PLCE1

8.92e-0478713EFO_0000668
Diseaseneuroimaging measurement

KRT17 SNAP91 SBNO1 TNRC6A LRCH4 DGKI NCKAP5 DMRT1 PLCE1

1.03e-031069719EFO_0004346
Diseasecortical surface area measurement

ARID1B KRT17 MYCBP2 BAZ2B TNRC6A DGKI NCKAP5 NOVA1 PLCE1 PDZD2

1.37e-0313457110EFO_0010736
DiseaseRenal glomerular disease

NPHP3 PLCE1

1.40e-0323712C0268731
DiseaseGlomerulopathy Assessment

NPHP3 PLCE1

1.40e-0323712C4521256
DiseaseAtaxia

CACNB4 PUM1

1.65e-0325712C0004134
Diseasesleep duration

MYCBP2 MAX PUM1 NOVA1 PDZD2

1.81e-03362715EFO_0005271
DiseaseEpileptic encephalopathy

PLAA NUP214

2.38e-0330712C0543888
Diseaserisk-taking behaviour

CDSN ARID1B KRT17 TNRC6A LRCH4 DGKI EIF4G3

2.40e-03764717EFO_0008579

Protein segments in the cluster

PeptideGeneStartEntry
SSGSLGSGEFTGVKE

EPS15L1

371

Q9UBC2
LGSSKSGDNSSSSLG

CACNB1

181

Q02641
SSFLGEKASAGLLGA

C4B

1176

P0C0L5
SASSGHSEFGGLGTL

BAZ2B

81

Q9UIF8
GLGGSSDGSSDVLAF

ACAP3

611

Q96P50
SGGSEAALKEGGSAA

ARID1B

101

Q8NFD5
ASLSKAAAGSAAGGF

ARID1B

471

Q8NFD5
SSSSASADLLAGFGG

SNAP91

661

O60641
LTGKGDSSGFSSYSG

CDSN

56

Q15517
FHGGKSSGNSSSSLG

CACNB4

171

O00305
GFGSSTGLSFADLAS

RANBP2

2841

P49792
ELSFLSVGGGGSSSG

TSPOAP1

741

O95153
SFDSKDGSGSAHGGL

IRX4

101

P78413
MGGGSNSSLSLDSAG

KAT2A

411

Q92830
GGLDSGFHSVDSGSK

LRCH4

296

O75427
SSGFGQHESGSGKSS

FLG2

971

Q5D862
GFGSGSPGNSSKDLS

KRT28

406

Q7Z3Y7
ISSSKGSLGGGFSSG

KRT10

36

P13645
SLKALSFSDGGSKLG

LZTS1

226

Q9Y250
AKGSTISAFDGGSDS

MAX

126

P61244
SLSSKASGSALGGES

GREB1

1131

Q4ZG55
GGGSSSVKGSSGEAF

KRT2

616

P35908
STKGGFSSNSASGGS

KRT79

11

Q5XKE5
KSGAAGGSAKSSSNG

LENG8

51

Q96PV6
FGFGGSVSGSSSSKI

KRT4

496

P19013
GSGGGDSKDKTSALS

GRIA3

806

P42263
KAGKGGAASGSDSAD

PIN4

11

Q9Y237
SGSVSAEAGFKGFGS

MUC19

346

Q7Z5P9
AEAGFKGFGSDSSSS

MUC19

351

Q7Z5P9
GGLATATTGAFSGKT

MUC19

6511

Q7Z5P9
TSAGLGLSLDGGKSS

PDZD2

2756

O15018
GGDSGLSSRGKKFAS

PFKFB3

266

Q16875
GGAFKTGSASIFDGS

CES5A

146

Q6NT32
SFGGTSLSAGKTSFS

NUP214

1426

P35658
STGGKVFGEGTAAAS

NUP214

2006

P35658
DSSGGKSSSSFARGA

KLLN

81

B2CW77
VSFSKGGELFASGGA

POC1B

276

Q8TC44
GSSSSLGATLGSALG

PUM1

676

Q14671
GLSGNLIASSFGKSA

PANK4

266

Q9NVE7
GGSGTAAISFTGALK

SLC37A1

311

P57057
SSSIKGSSGLGGGSS

KRT17

11

Q04695
SSSAGEEKGATGGSS

DGKI

56

O75912
LDGFSVFGGSSGSAL

EMILIN1

626

Q9Y6C2
DGSGSSLEGSALAGT

GJA3

376

Q9Y6H8
GGGYALASGSKSSGL

SLC13A4

471

Q9UKG4
GGFALAKGSEASGLS

SLC13A5

416

Q86YT5
KVGGLTGSSSDDSGS

SBNO1

721

A3KN83
SAFGSSLLGSGGSAF

PPP1R13L

216

Q8WUF5
GKGSSGGAKASETDA

EIF4G3

1076

O43432
FGKASGALVGAASGS

DMRT1

31

Q9Y5R6
SGSGASDLGAGSKKS

DMRT1

56

Q9Y5R6
GAGAEALAGALSKSS

LRRC74B

121

Q6ZQY2
AGGTAGTFALGSLAA

NOVA1

376

P51513
SGGGGFFSSLSNAVK

SYN1

71

P17600
SGASSALEAGGSSGL

RMDN3

221

Q96TC7
GSDKSLEGGGTAFDA

SMG5

496

Q9UPR3
SSGKGSLGSSGSFSS

NCKAP5

1346

O14513
AGGLLGASFKSTGSS

NPHP3

66

Q7Z494
SLGARSGLLSTFGGS

PLCE1

476

Q9P212
CKASSSSLIGGSGAG

PHF12

926

Q96QT6
GGDSAQSKSKSAGAG

SETD5

1086

Q9C0A6
GSIFFTGSASKGEDG

MYCBP2

601

O75592
PGDKLGGSGFKSSSS

OLIG2

66

Q13516
SGTGGGDAALDFKLA

ANKHD1

66

Q8IWZ3
SAGFSGGLSTSSGFD

TRO

1226

Q12816
SGFTSGLGEATAGLS

SPATC1

51

Q76KD6
GGSSKLFSSSFNGGR

RNF10

101

Q8N5U6
CSLSSGKFGTLLSGS

PLAA

116

Q9Y263
FLIGVSGGTASGKSS

UCK2

21

Q9BZX2
SSSGIGFGESLKAGS

NUP153

646

P49790
QKASGSSDKGGSFLT

WDR7

721

Q9Y4E6
GVGSSDLKASGSSGE

ZP2

671

Q05996
HLSNGESKSGGSYGT

TNRC6A

506

Q8NDV7
KLDSASFLGGGSSSG

ELFN2

556

Q5R3F8
SLGAGLGGSGFSATS

KRT75

511

O95678
GGSSSSFRAGSKGLS

KRT71

26

Q3SY84
SFRAGSKGLSGGFGS

KRT71

31

Q3SY84
SASFGSKSLSCLGGS

KRT72

41

Q14CN4