Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

KIF26B MYO18A WRNIP1 CHD1 CHD2 ABCA7 ABCC6 DNAH1 UBA7 DNAH12 ABCA6 CHTF18 CHD5 ABCB8 SMARCA2 SMARCA4 MACF1 ABCC10

9.31e-0661417718GO:0140657
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MYO18A WRNIP1 CHD1 CHD2 CHTF18 CHD5 SMARCA2 SMARCA4

1.78e-051271778GO:0008094
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD1 CHD2 CHD5 SMARCA2 SMARCA4

1.79e-05371775GO:0140658
GeneOntologyMolecularFunctionATP hydrolysis activity

MYO18A WRNIP1 CHD1 CHD2 ABCA7 ABCC6 DNAH12 ABCA6 CHTF18 CHD5 ABCB8 SMARCA4 MACF1 ABCC10

4.07e-0544117714GO:0016887
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

7.19e-05491775GO:0140359
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

CHDH SQLE AOX1 ACAD8 D2HGDH ILVBL

1.90e-04941776GO:0050660
GeneOntologyMolecularFunctioncytoskeletal protein binding

FKBP15 SYNPO2 SGIP1 NRAP KIF26B KNSTRN SYNPO2L MYO18A CLASP2 ADGRV1 DBN1 PICALM MEFV MAP3K1 NOD2 SPATC1 SPTBN4 PROM1 TLN1 MACF1 TLN2 USH2A

2.99e-04109917722GO:0008092
GeneOntologyMolecularFunctionactin binding

FKBP15 SYNPO2 NRAP SYNPO2L MYO18A CLASP2 DBN1 MEFV NOD2 SPTBN4 TLN1 MACF1 TLN2

3.58e-0447917713GO:0003779
GeneOntologyMolecularFunction1-phosphatidylinositol binding

FRMPD2 PICALM WDFY3

4.25e-04171773GO:0005545
GeneOntologyMolecularFunctionhelicase activity

WRNIP1 CHD1 CHD2 CHTF18 CHD5 SMARCA2 SMARCA4

5.30e-041581777GO:0004386
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

SGIP1 MYO18A WRNIP1 CHD1 CHD2 CHTF18 CHD5 SMARCA2 SMARCA4

5.66e-042621779GO:0140097
GeneOntologyMolecularFunctionCoA-transferase activity

ACAA1 OXCT1

7.68e-0451772GO:0008410
GeneOntologyMolecularFunctionactin filament binding

NRAP MYO18A CLASP2 DBN1 SPTBN4 TLN1 MACF1 TLN2

9.70e-042271778GO:0051015
DomainSNF2_N

CHD1 CHD2 CHD5 SMARCA2 SMARCA4

1.18e-05321775IPR000330
DomainSNF2_N

CHD1 CHD2 CHD5 SMARCA2 SMARCA4

1.18e-05321775PF00176
DomainMacrogloblnA2_thiol-ester-bond

A2M C4A C4B

4.53e-0581773IPR019565
DomainThiol-ester_cl

A2M C4A C4B

4.53e-0581773PF10569
DomainMacrogloblnA2_CS

A2M C4A C4B

4.53e-0581773IPR019742
DomainAAA

WRNIP1 ABCA7 ABCC6 DNAH12 ABCA6 CHTF18 ABCB8 ABCC10

6.99e-051441778SM00382
DomainAAA+_ATPase

WRNIP1 ABCA7 ABCC6 DNAH12 ABCA6 CHTF18 ABCB8 ABCC10

6.99e-051441778IPR003593
DomainChromo_domain

CHD1 CHD2 CHD5 CDYL2

7.14e-05241774IPR023780
DomainABC_tran

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

8.89e-05481775PF00005
DomainABC_TRANSPORTER_2

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

8.89e-05481775PS50893
Domain-

TLN1 TLN2

8.93e-05217721.20.1420.10
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

8.93e-0521772IPR014978
DomainSnAC

SMARCA2 SMARCA4

8.93e-0521772PF14619
DomainQLQ

SMARCA2 SMARCA4

8.93e-0521772SM00951
DomainVBS

TLN1 TLN2

8.93e-0521772PF08913
DomainQLQ

SMARCA2 SMARCA4

8.93e-0521772PS51666
DomainVinculin-bd_dom

TLN1 TLN2

8.93e-0521772IPR015009
DomainTalin_cent

TLN1 TLN2

8.93e-0521772IPR015224
DomainSnAC

SMARCA2 SMARCA4

8.93e-0521772SM01314
DomainSnAC

SMARCA2 SMARCA4

8.93e-0521772IPR029295
DomainTalin_middle

TLN1 TLN2

8.93e-0521772PF09141
DomainQLQ

SMARCA2 SMARCA4

8.93e-0521772PF08880
DomainA2M

A2M C4A C4B

9.56e-05101773PF00207
DomainA2M_N_2

A2M C4A C4B

9.56e-05101773IPR011625
DomainA2M_comp

A2M C4A C4B

9.56e-05101773IPR011626
DomainA2M_recep

A2M C4A C4B

9.56e-05101773PF07677
DomainA2M_comp

A2M C4A C4B

9.56e-05101773PF07678
DomainA2M_N

A2M C4A C4B

9.56e-05101773PF01835
DomainA2M_N

A2M C4A C4B

9.56e-05101773IPR002890
DomainA-macroglobulin_rcpt-bd

A2M C4A C4B

9.56e-05101773IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M C4A C4B

9.56e-05101773PS00477
DomainA2M_N_2

A2M C4A C4B

9.56e-05101773PF07703
DomainMacroglobln_a2

A2M C4A C4B

9.56e-05101773IPR001599
DomainABC_TRANSPORTER_1

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

9.83e-05491775PS00211
DomainChromo

CHD1 CHD2 CHD5 CDYL2

9.90e-05261774PF00385
DomainABC_transporter-like

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

1.08e-04501775IPR003439
DomainCHROMO_1

CHD1 CHD2 CHD5 CDYL2

1.34e-04281774PS00598
DomainCHROMO_2

CHD1 CHD2 CHD5 CDYL2

1.34e-04281774PS50013
DomainChromodomain-like

CHD1 CHD2 CHD5 CDYL2

2.28e-04321774IPR016197
DomainChromo/shadow_dom

CHD1 CHD2 CHD5 CDYL2

2.57e-04331774IPR000953
DomainCHROMO

CHD1 CHD2 CHD5 CDYL2

2.57e-04331774SM00298
Domain-

MYO18A WRNIP1 CHD1 CHD2 ABCA7 ABCC6 DNAH1 NOD2 DNAH12 ABCA6 CHTF18 CHD5 ABCB8 SMARCA2 SMARCA4 CARD11 ABCC10 AGAP2

2.66e-04746177183.40.50.300
DomainDUF4208

CHD1 CHD2

2.66e-0431772PF13907
DomainDUF4208

CHD1 CHD2

2.66e-0431772IPR025260
DomainTalin-1

TLN1 TLN2

2.66e-0431772IPR015710
DomainDUF4208

CHD1 CHD2

2.66e-0431772SM01176
DomainIRS

DOK3 TLN1 TLN2

2.82e-04141773PF02174
DomainIRS_PTB

DOK3 TLN1 TLN2

2.82e-04141773IPR002404
DomainGPS

ADGRG3 ADGRV1 ADGRA2 PKD1

2.90e-04341774SM00303
DomainGPS

ADGRG3 ADGRV1 ADGRA2 PKD1

3.25e-04351774PF01825
DomainGPS

ADGRG3 ADGRV1 ADGRA2 PKD1

3.62e-04361774PS50221
DomainGPS

ADGRG3 ADGRV1 ADGRA2 PKD1

4.03e-04371774IPR000203
DomainP-loop_NTPase

KIF26B MYO18A WRNIP1 CHD1 CHD2 ABCA7 ABCC6 DNAH1 NOD2 DNAH12 ABCA6 CHTF18 CHD5 ABCB8 SMARCA2 SMARCA4 CARD11 ABCC10 AGAP2

4.50e-0484817719IPR027417
DomainILWEQ_dom

TLN1 TLN2

5.29e-0441772IPR002558
DomainHSA

SMARCA2 SMARCA4

5.29e-0441772SM00573
DomainILWEQ

TLN1 TLN2

5.29e-0441772SM00307
DomainFERM_f0

TLN1 TLN2

5.29e-0441772PF16511
DomainILWEQ

TLN1 TLN2

5.29e-0441772PD011820
DomainHSA

SMARCA2 SMARCA4

5.29e-0441772PS51204
Domain-

TLN1 TLN2

5.29e-04417721.20.1410.10
DomainI_LWEQ

TLN1 TLN2

5.29e-0441772PF01608
DomainI_LWEQ

TLN1 TLN2

5.29e-0441772PS50945
DomainFERM_f0

TLN1 TLN2

5.29e-0441772IPR032425
DomainHSA_dom

SMARCA2 SMARCA4

5.29e-0441772IPR014012
DomainHSA

SMARCA2 SMARCA4

5.29e-0441772PF07529
DomainPDZ

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3 CARD11

5.31e-041481777SM00228
Domain-

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3 CARD11

5.75e-0415017772.30.42.10
DomainPDZ

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3 CARD11

5.99e-041511777PS50106
DomainTerpenoid_cyclase/PrenylTrfase

A2M C4A C4B

6.15e-04181773IPR008930
DomainChromodomain_CS

CHD1 CHD2 CDYL2

6.15e-04181773IPR023779
DomainPDZ

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3 CARD11

6.22e-041521777IPR001478
DomainABC_transporter_CS

ABCA7 ABCC6 ABCB8 ABCC10

6.59e-04421774IPR017871
DomainFYrich_C

KMT2B KMT2D

8.76e-0451772IPR003889
DomainFYrich_N

KMT2B KMT2D

8.76e-0451772IPR003888
DomainFYRC

KMT2B KMT2D

8.76e-0451772SM00542
DomainFYRN

KMT2B KMT2D

8.76e-0451772SM00541
DomainAnaphylatoxin_comp_syst

C4A C4B

8.76e-0451772IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

8.76e-0451772IPR001840
Domain-

AOX1 D2HGDH

8.76e-04517723.30.43.10
DomainFAD-bd_2_sub1

AOX1 D2HGDH

8.76e-0451772IPR016167
DomainFYRN

KMT2B KMT2D

8.76e-0451772PF05964
DomainFYRC

KMT2B KMT2D

8.76e-0451772PF05965
DomainFYRC

KMT2B KMT2D

8.76e-0451772PS51543
DomainFYRN

KMT2B KMT2D

8.76e-0451772PS51542
DomainBRK

SMARCA2 SMARCA4

1.31e-0361772SM00592
Domain-

AOX1 D2HGDH

1.31e-03617723.30.465.10
DomainBRK_domain

SMARCA2 SMARCA4

1.31e-0361772IPR006576
DomainFAD_PCMH

AOX1 D2HGDH

1.31e-0361772PS51387
DomainCO_DH_flavot_FAD-bd_sub2

AOX1 D2HGDH

1.31e-0361772IPR016169
DomainFAD-bd_2

AOX1 D2HGDH

1.31e-0361772IPR016166
DomainBRK

SMARCA2 SMARCA4

1.31e-0361772PF07533
DomainABC_membrane

ABCC6 ABCB8 ABCC10

1.46e-03241773PF00664
DomainANATO

C4A C4B

1.82e-0371772SM00104
DomainPKD

SORCS1 PKD1

1.82e-0371772PF00801
DomainVinculin/catenin

TLN1 TLN2

1.82e-0371772IPR006077
DomainANAPHYLATOXIN_2

C4A C4B

1.82e-0371772PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.82e-0371772PS01177
DomainANATO

C4A C4B

1.82e-0371772PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

1.82e-0371772IPR000020
DomainPDZ

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3

2.27e-031411776PF00595
PathwayKEGG_ABC_TRANSPORTERS

ABCA7 ABCC6 ABCA6 ABCB8 ABCC10

3.42e-05441205M11911
PathwayKEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION

ACAA1 AOX1 ACAD8 OXCT1 HSD17B10

3.42e-05441205M11835
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

STK36 ARHGEF19 ANKS6 KMT2B CLASP2 ADGRA2 ABCA7 GGT7 NOD2 URB1 KMT2D MEGF8 CDK13 CHD5 TLN1 PKD1 ANKRD34A TLN2 WDFY3 SLC45A1 MAPKBP1 SNAPC4 D2HGDH ABCC10

4.74e-0911051832435748872
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 CUX2 ADGRV1 ADGRA2 URB1 CAMKK2 CHD5 TLN1 MACF1 TLN2 WDFY3

3.49e-082251831112168954
Pubmed

BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.

SMARCA2 SMARCA4 EPAS1

5.71e-074183323897427
Pubmed

The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.

SRF SMARCA2 SMARCA4

1.42e-065183319342595
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC6 ABCA6 ABCB8 ABCC10

5.04e-062218348894702
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCA7 ABCC6 ABCB8 ABCC10

6.07e-0623183410708515
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

CUX2 PROM1 SMARCA2 SMARCA4

1.38e-0528183423643363
Pubmed

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.

SMARCA2 SMARCA4 ALAS2

2.29e-0511183318094026
Pubmed

Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.

WRNIP1 SMARCA2 SMARCA4 MED26 EPAS1

2.63e-0566183523275444
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.75e-052183222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.75e-052183216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.75e-052183215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.75e-052183219062096
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

2.75e-05218328670841
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.75e-052183219933335
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

2.75e-052183223163725
Pubmed

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.

NOD2 DMBT1

2.75e-052183217548659
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.75e-05218322459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.75e-052183217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.75e-052183212207352
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

2.75e-052183223076393
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.75e-052183227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.75e-052183222387014
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

2.75e-052183215576411
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.75e-052183223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.75e-052183223918728
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

2.75e-052183215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

2.75e-052183226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

2.75e-052183233027072
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.75e-05218323037333
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

2.75e-052183223872584
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.75e-052183211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.75e-05218324216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.75e-05218326950384
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

2.75e-052183223088494
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.75e-05218328660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.75e-05218328428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.75e-052183224638111
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

2.75e-052183220333683
Pubmed

Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).

KMT2B KMT2D

2.75e-052183235640156
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.75e-052183221345967
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

2.75e-052183234812766
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

2.75e-052183230478150
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.75e-05218322572548
Pubmed

The complement component C4 of mammals.

C4A C4B

2.75e-05218322302180
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.75e-052183222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.75e-052183218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.75e-052183229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

2.75e-05218326589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.75e-052183225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.75e-052183217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.75e-05218326149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.75e-05218326149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.75e-052183212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.75e-05218323542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.75e-05218322387317
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

2.75e-052183225808524
Pubmed

The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.

NOD2 MAPKBP1

2.75e-052183222700971
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

2.75e-052183219144648
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.75e-052183216908004
Pubmed

How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes.

ABCC6 PKD1

2.75e-052183218791038
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.75e-05218327365238
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.75e-05218327391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

2.75e-052183217971360
Pubmed

Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy.

JARID2 CELF1

2.75e-052183232632266
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

2.75e-052183229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

2.75e-052183217971229
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

2.75e-052183229391527
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

2.75e-05218326881182
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

2.75e-052183237634210
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

2.75e-052183217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

2.75e-052183221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

2.75e-05218326978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

2.75e-052183235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

2.75e-052183228873507
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

2.75e-05218328208605
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

2.75e-0521832276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

2.75e-05218326832377
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

2.75e-05218323794341
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

2.75e-052183222785613
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

2.75e-052183211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

2.75e-052183212620226
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

2.75e-052183232691186
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

2.75e-052183227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

2.75e-052183229848589
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

2.75e-052183215671307
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

2.75e-05218328390682
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

2.75e-05218323902619
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

2.75e-052183234638692
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.75e-05218327373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.75e-05218323696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.75e-05218321357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.75e-052183216098595
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

2.75e-052183215787745
Pubmed

Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.

TLN1 TLN2

2.75e-052183226822056
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

2.75e-052183230026462
Pubmed

CHD1 and CHD2 are positive regulators of HIV-1 gene expression.

CHD1 CHD2

2.75e-052183225297984
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

2.75e-05218326559257
Pubmed

Extracellular rigidity sensing by talin isoform-specific mechanical linkages.

TLN1 TLN2

2.75e-052183226523364
Pubmed

Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence.

ITGA2B TLN1

2.75e-052183217872456
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M C4A C4B

2.16e-05911731234
GeneFamilyPDZ domain containing

SYNPO2 FRMPD2 SYNPO2L MYO18A PARD6G TAX1BP3 CARD11

5.92e-0515211771220
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

2.47e-04411721244
GeneFamilySynaptotagmin like tandem C2 proteins

SYTL5 SYTL1

1.81e-03101172822
CoexpressionGSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_DN

STK36 TFAP2E ADGRV1 ITGA2B PICALM MEFV DNAH12 ABCA6 KLHL7 FCGRT

1.47e-0619918310M8093
CoexpressionBENPORATH_ES_WITH_H3K27ME3

NOL4 GPR6 DCHS2 TRH HTR6 TFAP2E CHDH OTOP3 ADGRA2 SORCS1 SPTBN4 OTP TRIM67 FOXD4L1 PLXNC1 CHD5 PRDM13 TMEM132E-DT DLX1 EPAS1 NOVA2 AGAP2

1.16e-05111518322M10371
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

SIGLEC8 SRF SLC39A4 ITGA2B MPIG6B LCMT2 ABCC6 MEGF8 CHD5 TCF25 ZNF324 TLN2 EFCC1 C4A C4B ALAS2 WDFY3 SNAPC4 CNGB1

2.18e-0590918319M41018
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

A2M PDK4 SIGLEC5 ABCA7 DNAH1 NOD2 MEGF8 FCGRT ZNF324 EFCC1

2.76e-0917218410f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M NOL4 STK36 KIF26B ADGRV1 DNAH1 SORCS1 HMCN1 TLN2 USH2A

5.29e-09184184102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M NOL4 STK36 KIF26B ADGRV1 DNAH1 SORCS1 HMCN1 TLN2 USH2A

5.29e-09184184102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M NOL4 STK36 KIF26B ADGRV1 DNAH1 SORCS1 HMCN1 TLN2 USH2A

5.29e-0918418410ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 PDK4 DOK3 ABCC6 MEFV KLHL31 CDYL2

4.30e-0711218479801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ANKS6 SYNPO2L KIRREL2 KLHL31 SLC25A43 CHTF18 DYRK2

4.86e-0711418472cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ANKS6 SYNPO2L KIRREL2 KLHL31 SLC25A43 CHTF18 DYRK2

4.86e-071141847fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF2BP2 ACAA1 TRH PDK4 SIGLEC5 PROM1 CHD5 CARD11

1.24e-06189184898f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF2BP2 ACAA1 TRH PDK4 SIGLEC5 PROM1 CHD5 CARD11

1.24e-061891848f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

A2M SYNPO2 SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

1.29e-0619018483a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGIP1 NRAP KNSTRN ADAMTSL3 ARHGEF39 ANKRD34A CDYL2

1.31e-06132184702491930097b75aaeedab9e8200711b0dc610944
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KNSTRN ABCC6 NOD2 TAX1BP3 CNGB1 NLRC3

1.44e-06851846bb9555652e93620d5aeeb71e915b3978a437407d
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

KNSTRN ABCC6 NOD2 TAX1BP3 CNGB1 NLRC3

1.44e-06851846f7935c3206310adafdecb75149c3b06c38e7780c
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

KNSTRN ABCC6 NOD2 TAX1BP3 CNGB1 NLRC3

1.44e-0685184643f6911b032718d8ba75fb7bba5f9b536a4b3260
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1 TLN2

1.63e-061961848bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IRF2BP2 ADGRG3 SIGLEC8 ITGA2B SGPP1 MACF1 NLRC3 EPAS1

1.63e-0619618485bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1 MACF1

1.63e-0619618487d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANKS6 GGT7 SPTBN4 HMCN1 ABCA6 AEBP1 CHTF18 TLN2

1.70e-061971848d7cef7881abd807a679432766ced609a6efd1067
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANKS6 GGT7 SPTBN4 HMCN1 ABCA6 AEBP1 CHTF18 TLN2

1.70e-06197184820a5958512bdb99daeb8f4d244df53e4f048f879
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1 MACF1

1.76e-0619818488f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SYNPO2 SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

1.90e-062001848389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TRH SIGLEC8 KLHL31 SPTBN4 PROM1 C9orf43 DMRTA1

3.65e-061541847ac539c8ca9e1d48b59bff8026775c2147543f3e2
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOL4 GPR6 ADGRV1 SYTL5 CHD5 DMRTA1 POTEJ

3.81e-061551847498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

A2M SGIP1 LRFN3 COL18A1 HMCN1 ABCA6 AEBP1

5.53e-0616418472ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellLA-04._Ventricular_Cardiomyocyte_I|LA / Chamber and Cluster_Paper

ITGA2B TAX1BP3 PROM1 B4GALNT3 SYTL1 NNT

6.49e-06110184634dcd1e1e16e8b6088ff9a7a40532e8bd000c121
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK3 MEFV CREBZF NOD2 HMCN1 WDFY3 OPLAH

7.27e-061711847e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 ABCA6 AEBP1 ANKRD34A NEXN-AS1 ALAS2

9.45e-06178184709475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 ABCA6 AEBP1 ANKRD34A NEXN-AS1 ALAS2

9.45e-061781847000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 ABCA6 AEBP1 ANKRD34A NEXN-AS1 ALAS2

9.45e-06178184735de8f791b0e78a6caf52ff095f05e204a59e828
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF19 CHDH ABCC6 COL18A1 ABCA6 C4B OPLAH

1.13e-051831847d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADGRG3 SGIP1 PARD6G ADAMTSL3 AFAP1L1 EFCC1 NOVA2

1.21e-0518518474a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADGRG3 SGIP1 PARD6G ADAMTSL3 AFAP1L1 EFCC1 NOVA2

1.21e-05185184736ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellfacs-Lung-EPCAM-24m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPK3BL2 ACAA1 KNSTRN SIGLEC5 C1QTNF12 METTL17 D2HGDH

1.26e-0518618479ce3bd121869215a4e6114a310f9d2fb5adaef61
ToppCellfacs-Lung-EPCAM-24m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPK3BL2 ACAA1 KNSTRN SIGLEC5 C1QTNF12 METTL17 D2HGDH

1.26e-051861847a7fd35eabcfb534019dfe5a8a600bf2ec47c1ac2
ToppCellfacs-Lung-EPCAM-24m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPK3BL2 ACAA1 KNSTRN SIGLEC5 C1QTNF12 METTL17 D2HGDH

1.26e-05186184718c40203463d4dd8558c04977d52e400a8268f90
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

A2M SYNPO2 SGIP1 ADAMTSL3 HMCN1 ABCA6 TLN2

1.30e-051871847bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

NOL4 GFRA4 TRIM67 CHD5 ANKRD34A TCF25 SLC45A1

1.30e-05187184761b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADGRG3 ANKS6 ITGA2B ABCA7 MED26 NLRC3 AGAP2

1.35e-0518818473638d85452de15a060146628fbbad9d2a36feb13
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ATG9B SGIP1 PARD6G ADGRA2 HMCN1 PLXNC1

1.39e-0518918471137583e21d874c201c20581ba1995e2bfa3de59
ToppCellfacs-Skin-Anagen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRH PARD6G PICALM MAP3K1 SGPP1 COL18A1 LYPLA1

1.44e-0519018473466cebab16964e94da130d0673fa32e7d90b5ed
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADGRG3 SGIP1 PARD6G ADAMTSL3 MAP3K1 CAMKK2 ABCA6

1.44e-0519018479ce301841ce9486701fa28eb2a9929e35d476878
ToppCellfacs-Skin-Anagen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRH PARD6G PICALM MAP3K1 SGPP1 COL18A1 LYPLA1

1.44e-051901847888ded899f0513d41bf655896d59ae8ef74e0978
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

ADGRG3 MYO18A DBN1 CARD11 SNAPC4 ABCC10 AGAP2

1.44e-051901847e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 MACF1

1.49e-0519118476688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRFN3 PCDHB15 AFAP1L1 HMCN1 PCDHGA12 EPAS1 NOVA2

1.49e-051911847dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

NRAP PDK4 KLHL31 KLHL7 MACROD2 B4GALNT3 NNT

1.54e-051921847ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 MACF1

1.54e-05192184799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF366 ABCC6 AFAP1L1 PROM1 HMCN1 FCGRT EPAS1

1.54e-0519218479ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF366 ABCC6 AFAP1L1 PROM1 HMCN1 FCGRT EPAS1

1.54e-051921847a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF366 ABCC6 AFAP1L1 PROM1 HMCN1 FCGRT EPAS1

1.54e-05192184766defad13bd8e79319741e43ddb056841710b1d7
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF12 MAP3K1 SGPP1 COL18A1 HMCN1 MACF1 C1QTNF12

1.60e-051931847eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

A2M ADGRG3 PARD6G DBN1 AFAP1L1 COL18A1 NOVA2

1.60e-05193184768eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M SGIP1 AOX1 HMCN1 ABCA6 MACF1 EFCC1

1.60e-05193184799525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M SGIP1 ADAMTSL3 HMCN1 ABCA6 MACF1 EFCC1

1.60e-051931847b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRAP KNSTRN ADAMTSL3 ARHGEF39 ANKRD34A AGAP2

1.62e-051291846739b263296c28554967362060b154f7a95e1341d
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF12 MAP3K1 SGPP1 COL18A1 HMCN1 MACF1 C1QTNF12

1.65e-0519418475d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

A2M SYNPO2 SGIP1 ADGRA2 COL18A1 AEBP1 EPAS1

1.65e-051941847d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRAP KNSTRN ADAMTSL3 ARHGEF39 ANKRD34A AGAP2

1.69e-051301846615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NRAP TRH CHDH ADGRV1 C9orf43 ABCA6

1.69e-0513018460a6b87635e650df431a88f2e6396abead84d901d
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 AOX1 HMCN1 ABCA6 AEBP1 MACF1

1.71e-051951847df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 AOX1 HMCN1 ABCA6 AEBP1 MACF1

1.71e-0519518474243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SGIP1 AOX1 HMCN1 ABCA6 AEBP1 MACF1

1.76e-05196184742e9828222a9663525d571633e8a454c30bfa7f8
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

A2M SGIP1 PDK4 PICALM ABCA6 FCGRT MACF1

1.82e-05197184747fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M SYNPO2 SGIP1 ADAMTSL3 ADGRA2 COL18A1 AEBP1

1.82e-05197184701249bd485a3734de87ae6ed9c749597f39c6335
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M ADGRA2 AFAP1L1 COL18A1 HMCN1 CDYL2 EPAS1

1.88e-051981847218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

1.88e-05198184726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

A2M SGIP1 KIF26B AOX1 HMCN1 ABCA6 AEBP1

1.88e-051981847df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M SGIP1 AOX1 HMCN1 ABCA6 AEBP1 MACF1

1.88e-051981847f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M ADGRA2 AFAP1L1 COL18A1 HMCN1 CDYL2 EPAS1

1.88e-05198184772e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M ADGRA2 AFAP1L1 COL18A1 HMCN1 CDYL2 EPAS1

1.88e-051981847e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M ADGRA2 AFAP1L1 COL18A1 HMCN1 CDYL2 EPAS1

1.94e-0519918479c40b3ee39860e9d8edafd007daec11abdd95435
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M ADGRA2 AFAP1L1 COL18A1 HMCN1 CDYL2 EPAS1

1.94e-05199184772b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M RELCH CHD2 CDK13 PRRC2C TCF25 MACF1

1.94e-051991847f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

2.01e-052001847b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

2.01e-052001847cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 PDK4 AOX1 ADAMTSL3 ABCA6 AEBP1

2.01e-052001847c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 ADAMTSL3 HMCN1 ABCA6 AEBP1 EFCC1

2.01e-05200184734f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

2.01e-052001847cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SGIP1 AOX1 ADAMTSL3 HMCN1 ABCA6 AEBP1

2.01e-052001847311fab076f2ceb258e3970eb21e39344b894042a
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

A2M SYNPO2 SGIP1 AOX1 COL18A1 HMCN1 AEBP1

2.01e-052001847d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

SYNPO2 SGIP1 ZNF366 SYNPO2L ABCA6 NOVA2

3.13e-051451846ffbdadea0185e5d3b85f2868d5ec82b50cf2e2a1
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Striatum / BrainAtlas - Mouse McCarroll V32

ADGRG3 ZNF366 ABCC6 HMCN1 CNGB1

4.43e-059418459d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Striatum / BrainAtlas - Mouse McCarroll V32

ADGRG3 ZNF366 ABCC6 HMCN1 CNGB1

4.43e-05941845858dda192747e71533736247bc9e135f763a8860
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Striatum / BrainAtlas - Mouse McCarroll V32

ADGRG3 ZNF366 ABCC6 HMCN1 CNGB1

4.43e-05941845901c4908d27a06c81853a02042cd331549e0e27d
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

SIGLEC5 HSD11B1L MEFV ARHGEF39 CDYL2 WDFY3

4.71e-05156184663b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

A2M SGIP1 SYNPO2L HMCN1 ABCA6 AEBP1

5.24e-0515918463f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellControl-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPTBN4 ABCA6 PCDHGA12 PLXNC1 TLN1 MACROD2

5.81e-051621846aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2B C9orf43 TRIM67 MEGF8 CHD5 ALAS2

6.02e-051631846953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF366 ABCC6 PROM1 HMCN1 FCGRT EPAS1

6.22e-0516418466a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF366 ABCC6 PROM1 HMCN1 FCGRT EPAS1

6.22e-051641846ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD2 ADGRA2 SGPP1 SPTBN4 SLC45A1 CNGB1

6.22e-051641846d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCellCOVID-19_Mild-PLT_0|COVID-19_Mild / Disease Group and Platelet Clusters

MPIG6B BFSP1 ABCB8 ANKRD34A MACF1 ABCC10

6.44e-051651846083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCellEndothelial-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

SGIP1 KIF26B PARD6G DBN1 NEXN-AS1 EFCC1

6.44e-05165184610087d8bd2985906ef19547fe77eb178ae5e1638
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNPO2 PDK4 AOX1 AEBP1 ARHGEF39 TLN2

6.65e-05166184694636dbc039f794c735960c3425e00bdd5523602
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALNT12 MSLNL CHTF18 DMRTA1 SYTL1 NLRC3

6.88e-0516718465d1919bea8e5a52ac6fc953caff15509b7142923
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALNT12 MSLNL CHTF18 DMRTA1 SYTL1 NLRC3

6.88e-051671846d8f497860d48342a3aaaad328f88e4d55ab4faeb
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF2BP2 UPK3BL2 KMT2B ACAA1 TRH NLRC3

7.11e-051681846ca65321259711321c175ede67bd67a47aad81d7a
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B SPTBN4 SLC25A43 CHD5 SYTL1 AGAP2

7.35e-051691846b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCellIonocyte-iono-1|World / Class top

DOK3 GFRA4 ABCC6 COL18A1 TLN2 EDRF1

7.35e-0516918464b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B SPTBN4 SLC25A43 CHD5 SYTL1 AGAP2

7.35e-05169184683d1bcf33872b01ea9614f608a3e4ab30df25c7e
DrugAlbendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A

ASXL1 KMT2B URB1 CAMKK2 CELF1 NFRKB SMARCA2 SMARCA4 MAPKBP1 SNAPC4 DYRK2

4.37e-07194180111547_DN
DiseaseBohring syndrome

ASXL1 KLHL7

3.46e-0521742C0796232
Diseasecortical thickness

A2M IRF2BP2 KMT2B GALNT12 ADGRV1 ADAMTSL3 ADGRA2 MAP3K1 AFAP1L1 COL18A1 PLXNC1 PKD1 MACROD2 MACF1 DMRTA1 SDR16C5 ABCC10 CRB2

1.10e-04111317418EFO_0004840
DiseaseAcne Vulgaris

MEFV NOD2

2.06e-0441742C0001144
DiseaseAcne

MEFV NOD2

2.06e-0441742C0702166
DiseasePyoderma Gangrenosum

MEFV NOD2

2.06e-0441742C0085652
Diseaseneuroimaging measurement

DCHS2 KMT2B KIF26B GALNT12 MAP3K1 AFAP1L1 COL18A1 CELF1 PRRC2C PKD1 MACROD2 SMARCA2 MACF1 TLN2 DMRTA1 SDR16C5 GABBR1

2.09e-04106917417EFO_0004346
Diseasecreatinine measurement

CUX2 TCF12 TRH KIF26B CHD2 ADGRV1 DBN1 GGT7 COL18A1 PLXNC1 PRRC2C TMEM132E-DT NLRC3 EPAS1 ABCC10 OPLAH

2.85e-0499517416EFO_0004518
Diseaseprostate cancer (is_marker_for)

KMT2B KMT2D CDK13 SMARCA2 SMARCA4 AGAP2

3.38e-041561746DOID:10283 (is_marker_for)
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

3.42e-0451742C3281201
Diseasealkaline phosphatase measurement

IRF2BP2 CUX2 ZNF366 SLC39A4 ATXN1L ABCA6 FCGRT PKD1 MACROD2 CDYL2 MACF1 B4GALNT3 DMBT1 C17orf107 ABCC10 GABBR1

3.55e-04101517416EFO_0004533
DiseaseLennox-Gastaut syndrome

CUX2 CHD2

5.11e-0461742C0238111
Diseaseretinitis pigmentosa (implicated_via_orthology)

USH2A CNGB1 CRB2

5.31e-04271743DOID:10584 (implicated_via_orthology)
DiseaseSezary Syndrome

KMT2D SMARCA4 CARD11

5.31e-04271743C0036920
DiseaseHidradenitis Suppurativa

MEFV NOD2

7.12e-0471742C0162836
DiseaseNephronophthisis, familial juvenile

ANKS6 MAPKBP1

7.12e-0471742C1855681
DiseasePolycystic kidney disease, type 2

ANKS6 PKD1

7.12e-0471742C2751306
Diseasesialic acid-binding Ig-like lectin 6 measurement

SIGLEC8 SIGLEC5

9.46e-0481742EFO_0008285
DiseasePolycystic Kidney, Type 1 Autosomal Dominant Disease

ANKS6 PKD1

9.46e-0481742C0887850
DiseaseRetinitis pigmentosa

PROM1 KLHL7 USH2A CNGB1

9.75e-04741744cv:C0035334
DiseaseColorectal Carcinoma

RELCH WNT8B FRMPD2 GALNT12 CHD1 ADAMTSL3 ABCC6 PROM1 ABCA6 CHD5 DMRTA1 EDRF1

9.86e-0470217412C0009402
Diseasecolorectal adenocarcinoma (is_implicated_in)

KMT2B DOK3 NOD2

1.15e-03351743DOID:0050861 (is_implicated_in)
Diseasefamilial Mediterranean fever (is_implicated_in)

MEFV NOD2

1.21e-0391742DOID:2987 (is_implicated_in)
DiseasePolycystic Kidney, Autosomal Dominant

ANKS6 PKD1

1.21e-0391742C0085413
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

1.21e-0391742DOID:0050340 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_implicated_in)

MAP3K1 KMT2D SMARCA4 BAG6 EPAS1

1.43e-031391745DOID:3908 (is_implicated_in)
Diseasecancer antigen 125 measurement

MSLNL D2HGDH

1.51e-03101742EFO_0010603
DiseaseAutism Spectrum Disorders

CHD2 JARID2 DLX1 USH2A

1.63e-03851744C1510586
Diseaserac GTPase-activating protein 1 measurement

USP8 C4B

2.19e-03121742EFO_0801985
Diseaseintracranial aneurysm (is_implicated_in)

KMT2D PKD1

2.19e-03121742DOID:10941 (is_implicated_in)
DiseaseAlzheimer disease

TRH ABCA7 PICALM SPATC1 CELF1 PRRC2C MACROD2 TLN2 C17orf107

2.44e-034851749MONDO_0004975
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

2.58e-03131742C0265338
DiseaseFetal Alcohol Spectrum Disorders

SRF BPIFA1

2.58e-03131742C2985290
DiseaseArthritis, Psoriatic

MEFV NOD2

3.00e-03141742C0003872
Diseasepolycystic kidney disease (implicated_via_orthology)

ANKS6 PKD1

3.00e-03141742DOID:0080322 (implicated_via_orthology)
Diseaseasthma, chronic obstructive pulmonary disease

GALNT12 PLXNC1 D2HGDH

3.22e-03501743EFO_0000341, MONDO_0004979
DiseaseRetinitis Pigmentosa

PROM1 KLHL7 USH2A CNGB1

3.40e-031041744C0035334
Diseaseatopic eczema

DCHS2 PLXNC1 SMARCA4 DMRTA1 CARD11 D2HGDH

3.92e-032521746EFO_0000274
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SGPP1 SMARCA4

4.44e-03171742OBA_2045173
DiseaseFetal Alcohol Syndrome

SRF BPIFA1

4.44e-03171742C0015923
Diseaseheart failure

SGIP1 SYNPO2L PROM1 PKD1 EPAS1

4.91e-031851745EFO_0003144
Diseasecancer (implicated_via_orthology)

CUX2 SQLE SMARCA2 SMARCA4 MACF1 EPAS1

5.28e-032681746DOID:162 (implicated_via_orthology)
Diseasehearing threshold measurement, hearing measurement

FKBP15 MYO18A MACROD2

5.65e-03611743EFO_0007616, EFO_0007618
Diseaseserum non-albumin protein measurement

CUX2 ZNF366 SPATC1 USP8 FCGRT DMRTA1 CARD11

5.77e-033611747EFO_0004568

Protein segments in the cluster

PeptideGeneStartEntry
RLGPAIGLSAGQSQL

UPK3BL1

6

B0FP48
RGGGQLDLLGVSLAS

CHTF18

211

Q8WVB6
LGSSTLLQGGDLLRA

EPAS1

851

Q99814
SGGSSGLRLTAQLLL

HTR6

386

P50406
VTAVNRGLLGSGGLL

BPIFB3

56

P59826
SGAAAAGALPQGLSR

CXorf49;

301

A8MYA2
FLLSTRAGGLGINLA

CHD5

1096

Q8TDI0
RAGGLGINLATADTV

CHD5

1101

Q8TDI0
GDTLNLNLRAVGSGA

C4B

486

P0C0L5
SEGQGFLIAVRGLNG

ACAD8

261

Q9UKU7
QGVLSSLLGSLGARA

BAG6

706

P46379
LSGNFERSAGLQAGI

B4GALNT3

851

Q6L9W6
LGSSRNSPGAGLQLE

ADGRA2

1231

Q96PE1
FVLGANLNGGERLVS

AEBP1

756

Q8IUX7
LAGATAGLNVGSLAG

CELF1

321

Q92879
SGAGKSSLLNILNGL

ABCA6

516

Q8N139
ALAVERGSSLGAGNV

SPATA5

731

Q8NB90
FNISLISVAGGGRLG

ADGRV1

4001

Q8WXG9
GDGSGVLNNRLVGLS

ADGRG3

171

Q86Y34
QLSSLRGEGRGGLAL

AGAP2

496

Q99490
QGAFLRGSGLSLASG

C1QTNF12

181

Q5T7M4
GAALEGSALANGRAL

DLX1

191

P56177
SLQGARVLLTGANAG

HSD11B1L

26

Q7Z5J1
GQRLFGESILGLTQG

CUX2

1066

O14529
LLSTRAGGLGINLAS

CHD1

861

O14646
SQSEQGLLLGGASAA

CDK13

151

Q14004
LGLRAEGATTAGQAA

EFCC1

86

Q9HA90
SSGSLALGSAAIRGQ

ASXL1

206

Q8IXJ9
QVAQTAGSGLARLGL

ABCA7

1901

Q8IZY2
RSSGSLLNNAIKGGV

A2M

1081

P01023
QALLSGRQAKGLTSG

ARHGEF39

211

Q8N4T4
RGALGQQQSLGARAL

CHDH

16

Q8NE62
TEQIRLLGGFQSLGG

ANKRD34A

476

Q69YU3
GAAAGGARLSSLPQA

TFAP2E

16

Q6VUC0
VGLGSRAAGQAAALV

AOX1

1016

Q06278
AASLQAQRGSGGARL

C17orf113

436

A0A1B0GUU1
AQRGSGGARLQGFLQ

C17orf113

441

A0A1B0GUU1
TGAGSGLGRLLALQF

SDR16C5

46

Q8N3Y7
KSRLLQASGGGLTGA

PCDHGA12

721

O60330
FVLRSAGSLNGAGLV

PDK4

6

Q16654
LGRNSAARALISGSG

ARHGEF19

211

Q8IW93
GGGQLNRAGSISTLD

RELCH

171

Q9P260
GEGGRSLSLGQRQLL

ABCC10

1376

Q5T3U5
RGSLLELGQGLQRAS

OTOP3

496

Q7RTS5
NALNGLLEGGNGLSC

KLHL31

31

Q9H511
AGGGANGSLELSSQL

GPR6

46

P46095
GANLSGLGRNIILTT

NFRKB

1211

Q6P4R8
LTSLDLRGNSIGPQG

NLRC3

696

Q7RTR2
AAELANARGLGLQGA

NRAP

1681

Q86VF7
NASSGRLLGGLSLAF

CRB2

886

Q5IJ48
AAARGGLSLLSQGES

EDRF1

16

Q3B7T1
ALALALNKTSGGGGR

GABBR1

476

Q9UBS5
VAGQSQAGARVSLGG

ATXN1L

51

P0C7T5
LLQGGAGARGLQLRA

KIF26B

1811

Q2KJY2
LQLRFLRNGLAAGTG

FCGRT

231

P55899
NRTVLFLGTGDGQLL

PLXNC1

386

O60486
LGANGAARGLSGLTQ

GGT7

561

Q9UJ14
GSIAGLEGGSQLALR

MYO18A

986

Q92614
ATGQASSLLGGRLLG

COL18A1

1716

P39060
SSLLGGRLLGQSAAS

COL18A1

1721

P39060
SGGARLASLFGLDQA

FKBP15

16

Q5T1M5
INGSDSILGTRGNAA

TCF12

316

Q99081
GSNSAGQLALSGRNV

HERC6

206

Q8IVU3
GNALLVGLGGSGRQS

DNAH12

2251

Q6ZR08
GTGAGRKGLLSQDNL

MEGF8

2826

Q7Z7M0
ARAQLNQLSLDGGTG

DOK3

11

Q7L591
SGALQGGLRQVLQGL

KMT2B

1406

Q9UMN6
GGSLGNNVSGRVLNS

KLHL7

436

Q8IXQ5
GNRLTSLGEGQLRGL

LRFN3

116

Q9BTN0
NASSAGRLQGLAGGA

MEFV

206

O15553
GAGLRLSASDQQLLG

MSLNL

166

Q96KJ4
LLQRGASAAARSGTG

ANKRD65

126

E5RJM6
GATALGLAAALGRSQ

ANKRD65

236

E5RJM6
AGAIGQRLSNGLARL

DBN1

126

Q16643
RGSFVANLANDLGLG

PCDHB15

41

Q9Y5E8
LGLGLNSAAASGVLA

NOVA2

296

Q9UNW9
EAALRGLAGATGSAN

MED26

91

O95402
LQRHGAGAGGTRNIS

ALAS2

216

P22557
GLGLATAERLVGQGA

HSD17B10

21

Q99714
SAAGGQGNSRRGLNK

MACF1

7351

Q9UPN3
GSLSRVNGAGLAQRL

PARD6G

321

Q9BYG4
GFGLGGLRLTALQAQ

HPDL

206

Q96IR7
SNGLQVLSGGRILAL

HMCN1

2056

Q96RW7
FLNGSLGAGEQRELT

DCHS2

1036

Q6V1P9
SGPNLRAGVLLTSGN

DERPC

181

P0CG12
RQALGNALLLGVGGS

DNAH1

2576

Q9P2D7
NALLLGVGGSGRSSL

DNAH1

2581

Q9P2D7
LGGAASTLLQNRGAL

ILVBL

146

A1L0T0
GLAGSLTNALSNGLL

BPIFA1

46

Q9NP55
LTNALSNGLLSGGLL

BPIFA1

51

Q9NP55
LLLLLGSASSVGGNR

GFRA4

11

Q9GZZ7
STRAGGLGINLASAD

CHD2

866

O14647
LFVSRLQGAAGGLLS

FRMPD2

686

Q68DX3
AGATSLAALQGLGER

BFSP1

36

Q12934
FLGLSGNQSAGTRVG

C9orf43

166

Q8TAL5
GAALGLGALRQASGS

DMRTA1

191

Q5VZB9
SGSLGSSQLRGALQA

CAPNS2

166

Q96L46
AQLLSGRGGSGAQLR

TMEM132E-DT

91

A2RUQ5
AGAAVGASARLLVQG

C17orf107

136

Q6ZR85
GGLLGRQQSGSQFAL

SQLE

51

Q14534
GQLQNLGAAVAILGG

CCS

81

O14618
AGLGSVLRAQRGAGA

GALNT12

31

Q8IXK2
GELLNRSGGSIDNVL

ANKS6

651

Q68DC2
GGSAAFLSRGLALNV

ATG9B

386

Q674R7
NRIILGGFSQGGALS

LYPLA1

111

O75608
GRSGLLGELRNNLFT

MAPKBP1

221

O60336
AATAAASGGGLRQRL

FOXD4L1

366

Q9NU39
LQERSQGGLAAGGSL

CAMKK2

101

Q96RR4
SARNRLGEGGAQASL

KIRREL2

486

Q6UWL6
AGSESTLALRLVNGG

DMBT1

1501

Q9UGM3
SSSKQGAGLALGRLL

PRDM13

316

Q9H4Q3
LAFGLGTGLATLSRN

SLC45A1

646

Q9Y2W3
QLQASPGLGAGATRS

DYRK2

26

Q92630
TALGLGGRAAASLAA

IRF2BP2

201

Q7Z5L9
LTAGRLLGFEANGAN

IRF2BP2

331

Q7Z5L9
ALANGAQLLLLGSAG

METTL17

66

Q9H7H0
LNGDSLTSQLTLLGG

CARD11

671

Q9BXL7
LTSQLTLLGGNARGS

CARD11

676

Q9BXL7
GGDLRAASNIIFSNG

DPP7

401

Q9UHL4
GDTLNLNLRAVGSGA

C4A

486

P0C0L4
GGNVATNAGGLRFLR

D2HGDH

201

Q8N465
ESLDLSIQNRGGSGL

PKD1

371

P98161
SSQLDGLSVSLGRLG

PKD1

4191

P98161
GLSNSLAGSNGAGLQ

OTP

251

Q5XKR4
GIAGSLKTVNGLLGN

JARID2

51

Q92833
LGRGIALFQGLSNIA

ABCB8

371

Q9NUT2
VSGALLLANGESTGN

MAP3K1

591

Q13233
AIVNAANASLLGGGG

MACROD2

86

A1Z1Q3
AGLSTQGTARLGNAL

NNT

636

Q13423
GAAGVNRLSIGLQSL

RSAD1

146

Q9HA92
ALANRQLGGTRLSLG

SYTL1

501

Q8IYJ3
SRGLLDGLVNGAASS

SYNPO2L

731

Q9H987
NIFLGGVRLNSGSGV

SYTL5

671

Q8TDW5
QLSRNGNLLFLGGSE

USH2A

3716

O75445
RLGPAIGLSAGQSQL

UPK3BL2

6

E5RIL1
GLQAVASIAGGIRNG

ACAA1

126

P09110
TRAGGLGLNLQAADT

SMARCA2

1126

P51531
QTQAALRGGIFGLLG

ABCC6

981

O95255
QLDINTVAAGGGSRL

OPLAH

346

O14841
LLSRAQGNPGASLDG

MPIG6B

11

O95866
NSINSVLGGGILDRL

PROM1

231

O43490
LLTSGQGALDQEALG

SLC39A4

31

Q6P5W5
ADLAGGTTVAAGNLL

KNSTRN

41

Q9Y448
SALALAGSALLRGGA

SFT2D3

116

Q587I9
QLGQASGLGGSQLID

PRRC2C

2526

Q9Y520
GLLENLSNGVTAGNG

POTEJ

391

P0CG39
GALRRNSLTGEEGQL

SGPP1

106

Q9BX95
TRAGGLGLNLQSADT

SMARCA4

1156

P51532
GSVLLLQGRSNLGTG

SIGLEC5

421

O15389
GNGSSLSVLEGQSLR

SIGLEC8

266

Q9NYZ4
TGGQRLLCAGLAGTL

SLC25A43

11

Q8WUT9
NAGVDNFGLGLLLRS

OXCT1

91

P55809
GSQQAGTTLNLDLGG

ITGA2B

556

P08514
LGGGLLNLNDASSSG

NOL4

561

O94818
DASLGTFGRGGNLTL

URB1

326

O60287
LGDPSTGLLIRANQG

TRPT1

91

Q86TN4
AGIRRNVASALGNLG

STK36

1206

Q9NRP7
ALGRGSALGGSLNRT

SRF

11

P11831
RLQQSLAGGPALGLS

AFAP1L1

696

Q8TED9
AENGLGSALTNGGLN

CDYL2

201

Q8N8U2
ISLLAVGGGNRRTAN

CNGB1

1031

Q14028
AGQSVRSGRLGAGAL

CLASP2

386

O75122
DSSLANLVGNLGIGN

PICALM

541

Q13492
LQGAGNSAAGRGAIA

WNT8B

221

Q93098
AARSSVLQRGAQGLG

ZFP92

121

A6NM28
LSRGSGLQAGAAAAA

TRIM67

51

Q6ZTA4
SSFTIGLRGLINLGN

USP27X

71

A6NNY8
RLLLGSGSGQASVSL

ZNF324

146

O75467
RLNGDNAGISVLPGS

WDFY3

2981

Q8IZQ1
LSLLQNSEGKRGTGA

SYNPO2

711

Q9UMS6
AGAQVLAEGLRGNTS

NOD2

886

Q9HC29
LAEGLRGNTSLQFLG

NOD2

891

Q9HC29
QGARVLVSGLQGLGA

UBA7

31

P41226
GLGEATAGLSSRQNN

SPATC1

56

Q76KD6
GGVGSLLARFQLSEG

SGIP1

766

Q9BQI5
GGLRSLAQAARGVAA

TLN1

1126

Q9Y490
NGTGLRNRNGSAIGL

TMEM39A

31

Q9NV64
DLLQRLLNGIGGCSS

CREBZF

161

Q9NS37
LRQGENLILGFSIGG

TAX1BP3

21

O14907
GLRRQLATLGGASGA

SPTBN4

831

Q9H254
SDGDARAGLNGLQLA

WRNIP1

436

Q96S55
QGLGRGRIALAQTAG

ZNF366

566

Q8N895
ALTLNLTGVPGGRAQ

TRH

11

P20396
LTAAGSIGQASGDLL

TLN2

641

Q9Y4G6
QAALGASEAGGLLQL

ZNF526

651

Q8TF50
AGALQASLGLVRGQL

SNAPC4

1341

Q5SXM2
LTLRNLQALGTLAGG

STRCP1

1181

A6NGW2
EQQLLLLGGGGNCFS

LCMT2

651

O60294
AGGGSQARLSALLAG

SORCS1

6

Q8WY21
GSGPALTGLRNLGNT

USP8

771

P40818
GVAGGLNRNQGLNRL

TCF25

631

Q9BQ70
GVSGQGRDNALTLLI

UNC45A

306

Q9H3U1
NGESSRESGGNLRLL

ZNF34

171

Q8IZ26
RGGSLSGNVSLLFNG

ADAMTSL3

1336

P82987
LAGSQQQLSLGLAGA

KMT2D

3306

O14686
NGQSQLRGAFGSGAL

KMT2D

4586

O14686
GRGLGALAANTSAPA

NEXN-AS1

211

Q8NBZ9