Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24	3.46e-07	37	32	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24	3.86e-07	38	32	4	GO:0070001
GeneOntologyMolecularFunction	chromatin binding	HMGN2 CHD6 CHD7 CHD4 SCML2 ZNF276 TOP2B POLR3G H1-3	1.62e-06	739	32	9	GO:0003682
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD6 CHD7 CHD4	2.80e-05	37	32	3	GO:0140658
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD6 CHD7 CHD4 TOP2B	4.89e-05	127	32	4	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	CHD6 CHD7 CHD4 ERVK-7 TOP2B	5.64e-05	262	32	5	GO:0140097
GeneOntologyMolecularFunction	histone binding	CHD6 CHD7 CHD4 SCML2 PHIP	5.95e-05	265	32	5	GO:0042393
GeneOntologyMolecularFunction	zinc ion binding	ERVK-5 CHD4 ERVK-7 ZNF276 ERVK-21 ERVK-9 ERVK-24 AEBP1	6.16e-05	891	32	8	GO:0008270
GeneOntologyMolecularFunction	chromatin DNA binding	HMGN2 CHD4 ZNF276 H1-3	1.41e-04	167	32	4	GO:0031490
GeneOntologyMolecularFunction	nucleosomal DNA binding	HMGN2 CHD4 H1-3	1.67e-04	67	32	3	GO:0031492
GeneOntologyMolecularFunction	structural molecule activity	ERVK-5 ERVK-7 ERVK-21 ERVK-9 ERVK-24 AEBP1 H1-3	4.35e-04	891	32	7	GO:0005198
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-5 CHD4 ERVK-7 ZNF276 ERVK-21 ERVK-9 ERVK-24 AEBP1	4.49e-04	1189	32	8	GO:0046914
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	CHD6 CHD7 CHD4 ERVK-7 TOP2B POLR3G	4.91e-04	645	32	6	GO:0140640
GeneOntologyMolecularFunction	nucleosome binding	HMGN2 CHD4 H1-3	5.13e-04	98	32	3	GO:0031491
GeneOntologyMolecularFunction	helicase activity	CHD6 CHD7 CHD4	2.04e-03	158	32	3	GO:0004386
GeneOntologyMolecularFunction	peptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24 AEBP1	3.59e-03	654	32	5	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24	4.73e-03	430	32	4	GO:0004175
GeneOntologyBiologicalProcess	viral process	ERVK-5 ERVK-7 ERVK-21 ERVK-9 ERVK-24 TOP2B	4.71e-05	464	30	6	GO:0016032
GeneOntologyBiologicalProcess	DNA topological change	HMGB2 TOP2B	9.14e-05	10	30	2	GO:0006265
GeneOntologyBiologicalProcess	DNA recombination	HMGB2 CHD4 ERVK-7 TOP2B H1-3	1.74e-04	368	30	5	GO:0006310
GeneOntologyBiologicalProcess	chromatin organization	HMGB2 HMGN2 CHD6 CHD7 CHD4 CTR9 H1-3	2.41e-04	896	30	7	GO:0006325
GeneOntologyCellularComponent	chromatin	ANKRD11 HMGB2 HMGN2 CHD6 CHD7 CHD4 SCML2 CTR9 TOP2B H1-3	4.68e-05	1480	32	10	GO:0000785
HumanPheno	Cryptorchidism	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	1.34e-05	780	8	7	HP:0000028
HumanPheno	Generalized joint hypermobility	CHD7 AEBP1 PHIP	4.26e-05	48	8	3	HP:0002761
HumanPheno	Vertebral segmentation defect	ANKRD11 CHD7 CHD4 AEBP1	6.25e-05	162	8	4	HP:0003422
HumanPheno	Joint laxity	CHD7 AEBP1 PHIP	6.42e-05	55	8	3	HP:0001388
HumanPheno	Abnormality of refraction	ANKRD11 CHD6 CHD4 CAMSAP1 AEBP1 PHIP	1.55e-04	709	8	6	HP:0000539
HumanPheno	Vertebral fusion	ANKRD11 CHD4 AEBP1	1.56e-04	74	8	3	HP:0002948
HumanPheno	Abnormal testis morphology	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	1.67e-04	1129	8	7	HP:0000035
HumanPheno	Non-obstructive azoospermia	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	1.70e-04	1132	8	7	HP:0011961
HumanPheno	Astigmatism	ANKRD11 CHD4 CAMSAP1 AEBP1	1.96e-04	217	8	4	HP:0000483
HumanPheno	Azoospermia	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	1.97e-04	1157	8	7	HP:0000027
HumanPheno	Abnormal spermatogenesis	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	2.39e-04	1190	8	7	HP:0008669
HumanPheno	Abnormal palate morphology	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	2.55e-04	1202	8	7	HP:0000174
HumanPheno	Abnormal male internal genitalia morphology	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	3.20e-04	1243	8	7	HP:0000022
HumanPheno	Functional abnormality of male internal genitalia	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	3.68e-04	1269	8	7	HP:0000025
HumanPheno	Abnormal male reproductive system physiology	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	4.66e-04	1314	8	7	HP:0012874
HumanPheno	Abnormal male external genitalia morphology	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	5.03e-04	1329	8	7	HP:0000032
HumanPheno	Aplasia/hypoplasia involving the skeleton	ANKRD11 CHD6 CHD7 CHD4 AEBP1 PHIP PTHLH	5.39e-04	1343	8	7	HP:0009115
HumanPheno	Abnormal external genitalia	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	6.22e-04	1372	8	7	HP:0000811
HumanPheno	Abnormal finger morphology	ANKRD11 CHD6 CHD7 CHD4 AEBP1 PHIP PTHLH	6.63e-04	1385	8	7	HP:0001167
HumanPheno	Webbed neck	ANKRD11 CHD7 AEBP1	7.21e-04	124	8	3	HP:0000465
HumanPheno	Clinodactyly	ANKRD11 CHD6 CHD7 CAMSAP1 PHIP	7.48e-04	574	8	5	HP:0030084
HumanPheno	Abnormality of the male genitalia	ANKRD11 CHD6 CHD7 CHD4 CAMSAP1 AEBP1 PHIP	8.49e-04	1437	8	7	HP:0010461
Domain	Chromo_domain	CHD6 CHD7 CHD4	5.34e-06	24	27	3	IPR023780
Domain	BAT2_N	PRRC2A PRRC2C	6.03e-06	3	27	2	IPR009738
Domain	BAT2_N	PRRC2A PRRC2C	6.03e-06	3	27	2	PF07001
Domain	PRRC2	PRRC2A PRRC2C	6.03e-06	3	27	2	IPR033184
Domain	Chromo	CHD6 CHD7 CHD4	6.85e-06	26	27	3	PF00385
Domain	CHROMO_2	CHD6 CHD7 CHD4	8.62e-06	28	27	3	PS50013
Domain	CHROMO_1	CHD6 CHD7 CHD4	8.62e-06	28	27	3	PS00598
Domain	SNF2_N	CHD6 CHD7 CHD4	1.30e-05	32	27	3	PF00176
Domain	SNF2_N	CHD6 CHD7 CHD4	1.30e-05	32	27	3	IPR000330
Domain	Chromodomain-like	CHD6 CHD7 CHD4	1.30e-05	32	27	3	IPR016197
Domain	CHROMO	CHD6 CHD7 CHD4	1.43e-05	33	27	3	SM00298
Domain	Chromo/shadow_dom	CHD6 CHD7 CHD4	1.43e-05	33	27	3	IPR000953
Domain	DNA/RNA_helicase_DEAH_CS	CHD6 CHD7 CHD4	1.71e-05	35	27	3	IPR002464
Domain	DEAH_ATP_HELICASE	CHD6 CHD7 CHD4	2.20e-05	38	27	3	PS00690
Domain	BRK	CHD6 CHD7	3.01e-05	6	27	2	SM00592
Domain	BRK_domain	CHD6 CHD7	3.01e-05	6	27	2	IPR006576
Domain	BRK	CHD6 CHD7	3.01e-05	6	27	2	PF07533
Domain	Helicase_C	CHD6 CHD7 CHD4	4.84e-04	107	27	3	PF00271
Domain	HELICc	CHD6 CHD7 CHD4	4.84e-04	107	27	3	SM00490
Domain	Helicase_C	CHD6 CHD7 CHD4	4.97e-04	108	27	3	IPR001650
Domain	HELICASE_CTER	CHD6 CHD7 CHD4	5.11e-04	109	27	3	PS51194
Domain	HELICASE_ATP_BIND_1	CHD6 CHD7 CHD4	5.11e-04	109	27	3	PS51192
Domain	DEXDc	CHD6 CHD7 CHD4	5.11e-04	109	27	3	SM00487
Domain	Helicase_ATP-bd	CHD6 CHD7 CHD4	5.25e-04	110	27	3	IPR014001
Domain	SANT	CHD6 CHD7	2.36e-03	50	27	2	SM00717
Domain	SANT/Myb	CHD6 CHD7	2.55e-03	52	27	2	IPR001005
Domain	HMG_box_dom	HMGB2 CHD4	3.96e-03	65	27	2	IPR009071
Pathway	BIOCARTA_DNAFRAGMENT_PATHWAY	HMGB2 TOP2B	4.73e-05	10	15	2	M7239
Pathway	BIOCARTA_DNAFRAGMENT_PATHWAY	HMGB2 TOP2B	5.78e-05	11	15	2	MM1349
Pathway	REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION	HMGB2 H1-3	8.19e-05	13	15	2	M1018
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	HMGB2 H1-3	1.36e-03	52	15	2	M2341
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ANKRD11 PRAM1 HMGB2 HMGN2 CHD7 CHD4 SCML2 RRBP1 SLC4A1AP PRRC2A PHIP PRRC2C TOP2B	9.85e-13	954	32	13	36373674
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ANKRD11 PRR12 HMGN2 CHD6 CHD7 CHD4 SCML2 ZNF276 RRBP1 CTR9 TOP2B	1.14e-08	1294	32	11	30804502
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CHD7 CHD4 SCML2 RRBP1 SLC4A1AP PRRC2A CTR9 REXO1 TOP2B	2.27e-08	774	32	9	15302935
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-5 ERVK-7 ERVK-21 ERVK-9 ERVK-24	2.46e-08	94	32	5	21542922
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 PRAM1 HMGB2 HMGN2 CHD7 CHD4 PRRC2A CTR9 PRRC2C TOP2B	3.38e-08	1103	32	10	34189442
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	CHD4 SLC4A1AP CTR9 PRRC2C TOP2B H1-3	1.03e-07	251	32	6	31076518
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-24	5.72e-07	18	32	3	18664271
Pubmed	CHD chromatin remodelling enzymes and the DNA damage response.	CHD6 CHD4	8.20e-07	2	32	2	23954449
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CHD6 CHD7 CHD4 SCML2 SLC4A1AP PHIP TOP2B	1.11e-06	608	32	7	36089195
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HMGN2 CHD4 SCML2 RRBP1 CAMSAP1 PRRC2A PRRC2C TOP2B	1.56e-06	934	32	8	33916271
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HMGN2 CHD6 CHD7 CHD4 RRBP1 CTR9 PHIP TOP2B H1-3	2.00e-06	1318	32	9	30463901
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD6 CHD7	2.46e-06	3	32	2	28533432
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	PRR12 CHD6 CHD7 PHIP	3.07e-06	109	32	4	33554859
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TMEM131 SCML2 RRBP1 CAMSAP1 PRRC2A PRRC2C TOP2B	3.52e-06	724	32	7	36232890
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CHD6 CHD7 PHIP PRRC2C TOP2B H1-3	3.92e-06	469	32	6	27634302
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HMGB2 HMGN2 CHD6 CHD4 RRBP1 CTR9 PRRC2C TOP2B H1-3	4.17e-06	1442	32	9	35575683
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	PRR12 CHD6 PRRC2A PHIP PRRC2C TOP2B	4.22e-06	475	32	6	31040226
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 CHD7 CHD4 SCML2 CTR9	4.45e-06	268	32	5	33640491
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-7 ERVK-24	4.92e-06	4	32	2	10469592
Pubmed	HMGN3a and HMGN3b, two protein isoforms with a tissue-specific expression pattern, expand the cellular repertoire of nucleosome-binding proteins.	HMGB2 HMGN2	4.92e-06	4	32	2	11356838
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-7 ERVK-21	8.19e-06	5	32	2	12629516
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-5 ERVK-7	8.19e-06	5	32	2	11401426
Pubmed	Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.	CHD4 CTR9 TOP2B	8.52e-06	43	32	3	26030138
Pubmed	Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.	PRRC2A CTR9 PRRC2C TOP2B	1.21e-05	154	32	4	36490346
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ANKRD11 CHD4 CAMSAP1 PRRC2A PRRC2C	1.25e-05	332	32	5	37433992
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	ANKRD11 CHD6 CHD7 CHD4	1.30e-05	157	32	4	30186101
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	PRR12 HMGB2 CHD4 CTR9	2.09e-05	177	32	4	26206133
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	HMGB2 HMGN2 CHD4 TOP2B	2.23e-05	180	32	4	30110629
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CHD7 CHD4 PRRC2A PHIP PRRC2C H1-3	2.56e-05	653	32	6	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	CHD6 CHD4 RRBP1 PRRC2A PRRC2C H1-3	2.60e-05	655	32	6	35819319
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	CHD7 SCML2 RRBP1 PRRC2A	2.81e-05	191	32	4	31177093
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	HMGB2 CHD7 SCML2 RRBP1 PRRC2A	2.85e-05	394	32	5	27248496
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	RRBP1 PRRC2A PRRC2C TOP2B	3.50e-05	202	32	4	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CHD4 RRBP1 PRRC2A PRRC2C	3.50e-05	202	32	4	24639526
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PRR12 CHD6 CHD7 CHD4 CAMSAP1	3.77e-05	418	32	5	34709266
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	HMGN2 CHD4 PRRC2A CTR9 PRRC2C H1-3	4.80e-05	731	32	6	29298432
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	CHD4 RRBP1 CAMSAP1 CTR9 TOP2B	4.81e-05	440	32	5	34244565
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ANKRD11 PRR12 CHD6 CHD7 SCML2 SLC4A1AP PRRC2A CTR9	4.82e-05	1497	32	8	31527615
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TMEM131 CHD6 CHD7 SCML2 RRBP1 CAMSAP1	4.88e-05	733	32	6	34672954
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	RRBP1 PRRC2A PRRC2C H1-3	5.14e-05	223	32	4	20020773
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-21 ERVK-9	5.38e-05	12	32	2	14557543
Pubmed	Homozygous mutation of VPS16 gene is responsible for an autosomal recessive adolescent-onset primary dystonia.	CHD7 TOP2B	6.36e-05	13	32	2	27174565
Pubmed	Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.	CHD7 TOP2B	7.41e-05	14	32	2	28317875
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	HMGB2 HMGN2 RRBP1 PRRC2A PRRC2C H1-3	8.29e-05	807	32	6	22681889
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	RRBP1 PHIP PRRC2C TOP2B	8.38e-05	253	32	4	29911972
Pubmed	A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.	ANKRD11 CHD7	9.76e-05	16	32	2	10932191
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	HMGB2 HMGN2 CHD4 SLC4A1AP PRRC2C H1-3	1.08e-04	847	32	6	35235311
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	CHD4 SCML2 RRBP1 TOP2B	1.09e-04	271	32	4	32433965
Pubmed	LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.	PRRC2A PRRC2C	1.11e-04	17	32	2	37072811
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	CHD4 PRRC2A PRRC2C	1.11e-04	101	32	3	26949739
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	CHD4 SCML2 PHIP TOP2B H1-3	1.19e-04	533	32	5	30554943
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	RRBP1 SLC4A1AP PRRC2A PRRC2C H1-3	1.39e-04	551	32	5	34728620
Pubmed	PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.	PRRC2A PRRC2C	1.87e-04	22	32	2	38507412
Pubmed	Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.	HMGN2 CHD4 H1-3	1.99e-04	123	32	3	35583604
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	HMGB2 HMGN2 RRBP1 TOP2B	1.99e-04	317	32	4	30997501
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	RRBP1 PRRC2A PRRC2C POLR3G	2.29e-04	329	32	4	34316702
Pubmed	Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.	HMGB2 CHD4 TOP2B	2.39e-04	131	32	3	34551306
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	HMGB2 HMGN2 RRBP1 H1-3	2.43e-04	334	32	4	30425250
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	CHD4 RRBP1 SLC4A1AP PRRC2A CTR9 PRRC2C TOP2B	2.50e-04	1415	32	7	28515276
Pubmed	Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.	CTR9 REXO1	2.63e-04	26	32	2	33298525
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	HMGB2 HMGN2 CHD4 RRBP1 CTR9 TOP2B	2.86e-04	1014	32	6	32416067
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PRR12 RRBP1 CTR9 PRRC2C H1-3	2.98e-04	650	32	5	38777146
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	HMGN2 CAMSAP1 PRRC2A PRRC2C	3.26e-04	361	32	4	26167880
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	CAMSAP1 PHIP	3.28e-04	29	32	2	21834987
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	HMGB2 CHD4 RRBP1 CTR9 PRRC2C	3.31e-04	665	32	5	30457570
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	CHD4 PRRC2A PRRC2C	3.35e-04	147	32	3	28977470
Pubmed	Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein.	HMGB2 HMGN2	3.75e-04	31	32	2	37939376
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	TMEM131 RRBP1 PRRC2A PRRC2C	3.77e-04	375	32	4	32788342
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	CHD6 CHD7 RRBP1	3.77e-04	153	32	3	10718198
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	CHD4 CTR9	4.25e-04	33	32	2	33567268
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	PRAM1 CHD7 SCML2 H1-3	4.63e-04	396	32	4	26687479
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	HMGB2 SLC4A1AP PRRC2A PRRC2C	4.76e-04	399	32	4	35987950
Pubmed	A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.	CHD4 PHIP	5.07e-04	36	32	2	29089422
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	HMGB2 CHD6 CHD7 CHD4 CTR9 H1-3	5.67e-04	1153	32	6	29845934
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	PRR12 RRBP1 SLC4A1AP H1-3	6.03e-04	425	32	4	24999758
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CHD4 RRBP1 PRRC2A PRRC2C TOP2B	6.03e-04	759	32	5	35915203
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	CHD7 CHD4 H1-3	6.35e-04	183	32	3	36129980
Pubmed	Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.	CHD4 TOP2B	6.58e-04	41	32	2	15561718
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	PRR12 CHD6	7.23e-04	43	32	2	26487511
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	TMEM131 RRBP1 PRRC2A PRRC2C	8.23e-04	462	32	4	31138677
Interaction	SMC5 interactions	ANKRD11 PRAM1 HMGB2 HMGN2 CHD7 CHD4 SCML2 RRBP1 SLC4A1AP PRRC2A PHIP PRRC2C TOP2B	1.91e-10	1000	28	13	int:SMC5
Interaction	H3C1 interactions	HMGB2 HMGN2 CHD7 CHD4 RRBP1 CAMSAP1 CTR9 PHIP PRRC2C TOP2B H1-3	1.43e-08	901	28	11	int:H3C1
Interaction	H2BC21 interactions	PRR12 HMGN2 CHD7 CHD4 SCML2 PRRC2A CTR9 PHIP TOP2B H1-3	1.69e-08	696	28	10	int:H2BC21
Interaction	H2BC8 interactions	HMGB2 HMGN2 CHD6 CHD7 CHD4 SCML2 SLC4A1AP PHIP TOP2B	5.08e-08	576	28	9	int:H2BC8
Interaction	H2BC12 interactions	ANKRD11 HMGN2 CHD4 AEBP1 PRRC2A TOP2B H1-3	2.21e-07	322	28	7	int:H2BC12
Interaction	CENPA interactions	ANKRD11 HMGB2 HMGN2 CHD6 CHD7 PHIP TOP2B	6.40e-07	377	28	7	int:CENPA
Interaction	H2BC4 interactions	ANKRD11 HMGN2 AEBP1 PRRC2A TOP2B H1-3	1.26e-06	259	28	6	int:H2BC4
Interaction	HMGA1 interactions	HMGB2 CHD4 CAMSAP1 CTR9 PHIP TOP2B H1-3	1.30e-06	419	28	7	int:HMGA1
Interaction	CBX3 interactions	HMGB2 HMGN2 CHD7 CHD4 SCML2 SLC4A1AP PHIP TOP2B	1.88e-06	646	28	8	int:CBX3
Interaction	SSRP1 interactions	ANKRD11 HMGB2 CHD4 PRRC2A CTR9 PHIP REXO1 TOP2B	2.91e-06	685	28	8	int:SSRP1
Interaction	TWIST1 interactions	PRR12 CHD6 CHD7 CHD4 PHIP	3.38e-06	170	28	5	int:TWIST1
Interaction	POLR1G interactions	ANKRD11 HMGB2 CHD7 SLC4A1AP CTR9 PHIP TOP2B	3.61e-06	489	28	7	int:POLR1G
Interaction	CEBPA interactions	PRR12 PRAM1 HMGB2 HMGN2 CHD7 CHD4 PRRC2A CTR9 PRRC2C TOP2B	3.67e-06	1245	28	10	int:CEBPA
Interaction	HDAC4 interactions	ANKRD11 PRR12 HMGB2 CHD6 PRRC2A PHIP PRRC2C TOP2B	5.36e-06	744	28	8	int:HDAC4
Interaction	H3-3A interactions	HMGB2 CHD7 CHD4 SCML2 SLC4A1AP PHIP TOP2B H1-3	5.63e-06	749	28	8	int:H3-3A
Interaction	COIL interactions	ANKRD11 HMGB2 CHD6 CHD7 CHD4 CTR9 TOP2B	7.99e-06	552	28	7	int:COIL
Interaction	H3C15 interactions	HMGB2 HMGN2 CHD4 RRBP1 H1-3	8.83e-06	207	28	5	int:H3C15
Interaction	POU5F1 interactions	PRAM1 HMGB2 CHD7 CHD4 SCML2 TOP2B H1-3	1.15e-05	584	28	7	int:POU5F1
Interaction	H2BC3 interactions	HMGB2 HMGN2 CHD7 CHD4 SCML2 RRBP1	1.67e-05	406	28	6	int:H2BC3
Interaction	H3-5 interactions	HMGB2 CHD4 TOP2B H1-3	1.79e-05	114	28	4	int:H3-5
Interaction	SRP9 interactions	RRBP1 SLC4A1AP PRRC2A CTR9 PRRC2C TOP2B	2.22e-05	427	28	6	int:SRP9
Interaction	ZNF330 interactions	ANKRD11 CHD7 SLC4A1AP CTR9 PHIP TOP2B	2.83e-05	446	28	6	int:ZNF330
Interaction	H2BC9 interactions	HMGB2 HMGN2 CHD4 RRBP1 PRRC2A H1-3	2.83e-05	446	28	6	int:H2BC9
Interaction	H3-4 interactions	HMGN2 CHD6 CHD4 PRRC2C REXO1 H1-3	2.90e-05	448	28	6	int:H3-4
Interaction	RPL31 interactions	ANKRD11 HMGB2 HMGN2 CHD4 RRBP1 TOP2B H1-3	3.08e-05	680	28	7	int:RPL31
Interaction	RAD18 interactions	CHD4 SLC4A1AP CTR9 PRRC2C TOP2B H1-3	3.24e-05	457	28	6	int:RAD18
Interaction	SMARCA4 interactions	CHD7 CHD4 SCML2 RRBP1 PHIP TOP2B	3.45e-05	462	28	6	int:SMARCA4
Interaction	NAA40 interactions	HMGN2 CHD4 SCML2 RRBP1 CAMSAP1 PRRC2A PRRC2C TOP2B	3.90e-05	978	28	8	int:NAA40
Interaction	RPS16 interactions	HMGB2 CHD4 RRBP1 PRRC2A PRRC2C TOP2B H1-3	4.59e-05	724	28	7	int:RPS16
Interaction	PARP1 interactions	HMGB2 HMGN2 CHD6 CHD7 CHD4 CTR9 PHIP TOP2B H1-3	4.66e-05	1316	28	9	int:PARP1
Interaction	BRD3 interactions	HMGN2 CHD4 SCML2 PHIP TOP2B H1-3	5.01e-05	494	28	6	int:BRD3
Interaction	H3C3 interactions	CHD6 CHD7 CHD4 SCML2 PHIP TOP2B	5.07e-05	495	28	6	int:H3C3
Interaction	SOX5 interactions	CHD6 CHD7 PRRC2A PRRC2C	7.09e-05	162	28	4	int:SOX5
Interaction	NR2C2 interactions	HMGN2 CHD6 CHD7 CHD4 RRBP1 CTR9 PHIP TOP2B H1-3	7.69e-05	1403	28	9	int:NR2C2
Interaction	CEBPB interactions	HMGB2 HMGN2 CHD7 CHD4 RRBP1 PRRC2A CTR9 PRRC2C H1-3	9.56e-05	1443	28	9	int:CEBPB
Interaction	SRP68 interactions	HMGB2 CHD4 RRBP1 PRRC2A PRRC2C	1.62e-04	381	28	5	int:SRP68
Interaction	MEX3A interactions	ANKRD11 CHD4 CAMSAP1 PRRC2A PRRC2C	1.68e-04	384	28	5	int:MEX3A
Interaction	NECAP1 interactions	PHIP TOP2B H1-3	1.70e-04	78	28	3	int:NECAP1
Interaction	LRRC31 interactions	RRBP1 PRRC2A PRRC2C TOP2B	1.76e-04	205	28	4	int:LRRC31
Interaction	FBL interactions	CHD4 RRBP1 PRRC2A PHIP PRRC2C TOP2B	2.06e-04	639	28	6	int:FBL
Interaction	LINC00240 interactions	PRRC2A PRRC2C	2.21e-04	16	28	2	int:LINC00240
Interaction	NUCKS1 interactions	HMGN2 PHIP TOP2B H1-3	2.30e-04	220	28	4	int:NUCKS1
Interaction	KDM1A interactions	PRR12 HMGB2 CHD6 CHD7 CHD4 CAMSAP1 SLC4A1AP	2.36e-04	941	28	7	int:KDM1A
Interaction	H1-4 interactions	PRAM1 HMGN2 CHD4 CTR9 TOP2B H1-3	2.37e-04	656	28	6	int:H1-4
Interaction	APEX1 interactions	ANKRD11 HMGB2 HMGN2 CHD7 CHD4 SCML2 PRRC2A TOP2B	2.44e-04	1271	28	8	int:APEX1
Interaction	H1-2 interactions	HMGB2 HMGN2 CHD4 SLC4A1AP CTR9 H1-3	2.58e-04	666	28	6	int:H1-2
Interaction	DNAJC8 interactions	ANKRD11 SLC4A1AP CTR9 TOP2B	2.73e-04	230	28	4	int:DNAJC8
Interaction	CTR9 interactions	TMEM131 CHD4 CTR9 TOP2B	2.87e-04	233	28	4	int:CTR9
Interaction	RNF113A interactions	CHD6 CHD4 RRBP1 PRRC2A PRRC2C H1-3	3.16e-04	692	28	6	int:RNF113A
Interaction	SUPT16H interactions	HMGB2 CHD4 CTR9 PHIP TOP2B	3.21e-04	442	28	5	int:SUPT16H
Interaction	AR interactions	PRR12 HMGB2 CHD7 CHD4 SCML2 CTR9 TOP2B	3.27e-04	992	28	7	int:AR
Interaction	RACK1 interactions	HMGB2 TMEM131 CHD4 RRBP1 PRRC2A PRRC2C	3.47e-04	704	28	6	int:RACK1
Interaction	H2AC11 interactions	HMGN2 CHD4 PRRC2C H1-3	3.63e-04	248	28	4	int:H2AC11
Interaction	IFI16 interactions	CHD4 SLC4A1AP PRRC2A PHIP TOP2B H1-3	3.74e-04	714	28	6	int:IFI16
Interaction	MYH15 interactions	HMGN2 RRBP1	3.85e-04	21	28	2	int:MYH15
Interaction	NUMA1 interactions	CHD4 PHIP TOP2B POLR3G H1-3	4.22e-04	469	28	5	int:NUMA1
Interaction	ATXN1 interactions	HMGB2 CHD4 ZNF276 RRBP1 PRRC2A CTR9 PRRC2C	4.32e-04	1039	28	7	int:ATXN1
Interaction	LGR4 interactions	CHD4 RRBP1 PRRC2A PRRC2C	4.47e-04	262	28	4	int:LGR4
Interaction	SIRT7 interactions	CHD7 CHD4 PRRC2A PHIP PRRC2C H1-3	4.66e-04	744	28	6	int:SIRT7
Interaction	USP14 interactions	HMGB2 HMGN2 RRBP1 PRRC2A H1-3	5.10e-04	489	28	5	int:USP14
Interaction	HNRNPCL2 interactions	CHD4 SCML2 CTR9 PHIP	5.29e-04	274	28	4	int:HNRNPCL2
Interaction	RCOR1 interactions	CHD6 CHD7 CHD4 CAMSAP1 PHIP	5.35e-04	494	28	5	int:RCOR1
Interaction	H2AC12 interactions	HMGN2 CHD4 H1-3	5.76e-04	118	28	3	int:H2AC12
Interaction	TPR interactions	CHD4 RRBP1 PHIP PRRC2C	5.82e-04	281	28	4	int:TPR
Interaction	CIT interactions	HMGN2 CHD4 PRRC2A CTR9 PHIP PRRC2C TOP2B H1-3	5.95e-04	1450	28	8	int:CIT
Interaction	H2AC4 interactions	HMGN2 CHD4 SCML2 PRRC2A H1-3	5.96e-04	506	28	5	int:H2AC4
Interaction	H1-1 interactions	HMGB2 HMGN2 CHD4 CTR9 H1-3	6.01e-04	507	28	5	int:H1-1
Interaction	IKZF1 interactions	ANKRD11 HMGN2 CHD4 H1-3	6.38e-04	288	28	4	int:IKZF1
Interaction	MAPRE1 interactions	TMEM131 RRBP1 CAMSAP1 PRRC2A PRRC2C	6.40e-04	514	28	5	int:MAPRE1
Interaction	PRRC2C interactions	CHD4 RRBP1 PRRC2A PRRC2C	6.55e-04	290	28	4	int:PRRC2C
Interaction	TLX3 interactions	PRR12 HMGN2 CHD6 CHD7	6.63e-04	291	28	4	int:TLX3
Interaction	PAX7 interactions	PRR12 CHD6 CHD7	6.66e-04	124	28	3	int:PAX7
Interaction	RABL6 interactions	CHD4 CTR9 PDILT	7.64e-04	130	28	3	int:RABL6
Interaction	MED15 interactions	CHD4 CTR9 TOP2B	7.81e-04	131	28	3	int:MED15
Interaction	USP11 interactions	CHD4 PRRC2A CTR9 PRRC2C TOP2B	7.93e-04	539	28	5	int:USP11
Interaction	HDAC3 interactions	ANKRD11 PRAM1 CHD4 TOP2B	8.71e-04	313	28	4	int:HDAC3
Interaction	SFPQ interactions	CHD4 PRRC2A CTR9 PRRC2C TOP2B	9.64e-04	563	28	5	int:SFPQ
Interaction	CHAF1A interactions	HMGB2 CHD4 PRRC2C TOP2B	9.67e-04	322	28	4	int:CHAF1A
Interaction	TLX2 interactions	PRR12 CHD6 CHD7	9.86e-04	142	28	3	int:TLX2
Interaction	TCEANC2 interactions	SLC4A1AP CTR9	1.02e-03	34	28	2	int:TCEANC2
Interaction	SALL3 interactions	CHD7 CHD4	1.02e-03	34	28	2	int:SALL3
Interaction	NOP56 interactions	ANKRD11 CHD4 PRRC2A TOP2B H1-3	1.02e-03	570	28	5	int:NOP56
Interaction	H2AC14 interactions	HMGB2 HMGN2 H1-3	1.03e-03	144	28	3	int:H2AC14
Interaction	KLF8 interactions	PRR12 CHD7 PRRC2A PRRC2C	1.05e-03	329	28	4	int:KLF8
Interaction	RPS6 interactions	HMGB2 CHD6 CHD4 RRBP1 PHIP TOP2B	1.09e-03	874	28	6	int:RPS6
Interaction	SRP72 interactions	HMGB2 RRBP1 PRRC2A PRRC2C	1.10e-03	333	28	4	int:SRP72
Interaction	ZC3H18 interactions	HMGN2 CHD4 PRRC2A CTR9 PRRC2C H1-3	1.10e-03	877	28	6	int:ZC3H18
Interaction	H2AC18 interactions	HMGB2 HMGN2 H1-3	1.11e-03	148	28	3	int:H2AC18
Interaction	SMAD9 interactions	RRBP1 CAMSAP1 CTR9	1.22e-03	153	28	3	int:SMAD9
Interaction	RHBDD1 interactions	CHD7 SCML2 RRBP1 PRRC2A	1.26e-03	346	28	4	int:RHBDD1
Interaction	CPEB4 interactions	PRRC2A PHIP PRRC2C	1.29e-03	156	28	3	int:CPEB4
Interaction	EWSR1 interactions	PRR12 CHD4 RRBP1 SLC4A1AP PRRC2A H1-3	1.31e-03	906	28	6	int:EWSR1
Interaction	POLR1E interactions	CHD6 CHD7 CTR9 TOP2B	1.32e-03	350	28	4	int:POLR1E
Interaction	SOX6 interactions	CHD7 PRRC2A PRRC2C	1.32e-03	157	28	3	int:SOX6
Interaction	MAN2C1 interactions	PRRC2A H1-3	1.34e-03	39	28	2	int:MAN2C1
Interaction	RPL5 interactions	CHD4 RRBP1 PRRC2A PRRC2C TOP2B	1.34e-03	606	28	5	int:RPL5
Interaction	RNF181 interactions	PRRC2A PRRC2C H1-3	1.39e-03	160	28	3	int:RNF181
Interaction	PYHIN1 interactions	CHD4 CTR9 PHIP TOP2B	1.43e-03	358	28	4	int:PYHIN1
Interaction	WDR77 interactions	CHD4 PRRC2A PHIP PRRC2C	1.48e-03	361	28	4	int:WDR77
Interaction	LOC102724594 interactions	HMGB2 CHD4	1.48e-03	41	28	2	int:LOC102724594
Cytoband	16q24.3	ANKRD11 ZNF276	6.11e-04	52	32	2	16q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16q24	ANKRD11 ZNF276	4.08e-03	136	32	2	chr16q24
GeneFamily	Canonical high mobility group	HMGB2 HMGN2	4.02e-05	11	16	2	511
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	CHD6 CHD7	9.85e-04	53	16	2	532
Coexpression	MENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS	ANKRD11 HMGB2 CHD4 TOP2B	2.15e-06	90	27	4	M39250
Coexpression	GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP	HMGB2 HMGN2 AEBP1 PRRC2A	4.84e-05	198	27	4	M8041
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN	HMGB2 HMGN2 AEBP1 PRRC2A	5.03e-05	200	27	4	M8039
Coexpression	MENON_FETAL_KIDNEY_4_PODOCYTES	ANKRD11 CHD4 PHIP PRRC2C	5.64e-05	206	27	4	M39254
Coexpression	TABULA_MURIS_SENIS_LUNG_CLASSICAL_MONOCYTE_AGEING	HMGB2 HMGN2 CHD4 RRBP1 PRRC2C	7.84e-05	441	27	5	MM3765
Coexpression	FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN	HMGB2 HMGN2 TMEM131	1.04e-04	89	27	3	M7715
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	ANKRD11 HMGB2 CHD6 CHD7 ZNF276 SLC4A1AP PHIP TOP2B	2.07e-05	983	27	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	ANKRD11 HMGB2 TMEM131 CHD7 PHIP PRRC2C	2.24e-05	469	27	6	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	facebase_RNAseq_e9.5_OlfPlac_2500_K3	PRR12 HMGB2 HMGN2 CHD7 CAMSAP1 PRRC2A POLR3G H1-3	7.96e-05	1187	27	8	facebase_RNAseq_e9.5_OlfPlac_2500_K3
CoexpressionAtlas	e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500_4	ANKRD11 CHD7	1.20e-04	13	27	2	Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500_4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	HMGB2 CHD6 CHD7 SLC4A1AP PHIP TOP2B	1.42e-04	654	27	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_100	ANKRD11 CHD7 H1-3	2.57e-04	98	27	3	Facebase_RNAseq_e9.5_Mandibular Arch_100
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 CHD4 RRBP1 PRRC2C TOP2B	8.13e-08	184	27	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	HMGB2 HMGN2 CHD7 PHIP H1-3	1.23e-07	200	27	5	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	HMGB2 HMGN2 CHD7 PHIP H1-3	1.23e-07	200	27	5	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	HMGB2 HMGN2 CHD7 PHIP H1-3	1.23e-07	200	27	5	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGB2 HMGN2	3.79e-06	177	27	4	15d1de38e4f1a0d4a786d83ee92240f44bdff006
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGB2 HMGN2	3.79e-06	177	27	4	b41e975e8368e2618b015be095efe8c0e001c78b
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 RRBP1 PRRC2C TOP2B	4.51e-06	185	27	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 CHD4 PHIP PRRC2C	4.81e-06	188	27	4	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	ANKRD11 HMGB2 ZNF276 PRRC2C	5.22e-06	192	27	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	CHD6 RRBP1 PHIP PRRC2C	5.33e-06	193	27	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGB2 HMGN2 CHD7 H1-3	5.67e-06	196	27	4	4924a36a81d62863c1004b8c76f8096a1f89c548
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	RRBP1 PRRC2A PHIP PRRC2C	5.78e-06	197	27	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 H1-3	5.78e-06	197	27	4	106b0f9a0425facc634feb7498c9ba2c55edfbf8
ToppCell	Non-neuronal-Dividing-IPC-IPC-new\|World / Primary Cells by Cluster	HMGB2 HMGN2 CHD7 PHIP	5.90e-06	198	27	4	11d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCell	Non-neuronal-Dividing-IPC-IPC-new-9\|World / Primary Cells by Cluster	HMGB2 HMGN2 CHD7 PHIP	5.90e-06	198	27	4	c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 TOP2B	6.02e-06	199	27	4	ea75804c34989c99aab542e6d72617ed144819b6
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 TOP2B H1-3	6.02e-06	199	27	4	8e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCell	10x5'v1-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 TOP2B	6.02e-06	199	27	4	713dfd8552635645db5e0b5721c64e5c9b4aa06c
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 TOP2B H1-3	6.02e-06	199	27	4	fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 TOP2B H1-3	6.02e-06	199	27	4	cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 H1-3	6.02e-06	199	27	4	be425e9cb90a73289026b1b7cb581e1c02a8985e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HMGB2 HMGN2 CHD7 PHIP	6.14e-06	200	27	4	7c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 H1-3	6.14e-06	200	27	4	c28d4ca51d2e2a3a22784ee251975f16a55b0297
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	ANKRD11 CHD4 PRRC2C H1-3	6.14e-06	200	27	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HMGB2 HMGN2 CHD7 H1-3	6.14e-06	200	27	4	c792d1dbbe27ebd60f4770834f30882c1a625be5
ToppCell	10x5'v1-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 AEBP1 H1-3	6.14e-06	200	27	4	364f09eb9ae4913f5c80a29e943e1c0b2ffd5f93
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGB2 HMGN2 H1-3	6.26e-05	128	27	3	9ab55a0421cd970e0b8dabce67dd68e382a6bd41
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 HMGB2 HMGN2	1.26e-04	162	27	3	dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCell	droplet-Lung-LUNG-30m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 HMGB2 HMGN2	1.26e-04	162	27	3	2a4e09545e9874519f0f56e81065104987d81cd6
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 HMGB2 HMGN2	1.30e-04	164	27	3	2a230ea066decb798a0e6f2b96c7608c8e608031
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 HMGB2 HMGN2	1.30e-04	164	27	3	d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM131 AEBP1 PTHLH	1.33e-04	165	27	3	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGB2 HMGN2 H1-3	1.38e-04	167	27	3	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGB2 HMGN2 H1-3	1.40e-04	168	27	3	faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HMGB2 HMGN2 H1-3	1.45e-04	170	27	3	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGB2 TOP2B H1-3	1.48e-04	171	27	3	58bdcbc65062ac09f1c014e08302f938a3e6b252
ToppCell	Lymphoid-Lymphoid-B_cells_(cycle)\|Lymphoid / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	1.50e-04	172	27	3	f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	TMEM131 PRRC2A PTHLH	1.58e-04	175	27	3	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANKRD11 RRBP1 H1-3	1.58e-04	175	27	3	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD7 RRBP1 PRRC2C	1.58e-04	175	27	3	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	droplet-Marrow\|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 HMGB2 HMGN2	1.63e-04	177	27	3	0b8a1496c078874def0bfca0268136f1a84b82fd
ToppCell	C_00\|World / shred on cell type and cluster	ANKRD11 CHD6 PRRC2C	1.69e-04	179	27	3	da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCell	Lymphoid-Lymphoid-T_cells_(cycle)\|Lymphoid / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	1.74e-04	181	27	3	b6b41cd5d43543fe7a093033dae52a789199db0e
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGB2	1.77e-04	182	27	3	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 PRRC2C TOP2B	1.77e-04	182	27	3	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGB2	1.77e-04	182	27	3	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 PRRC2C TOP2B	1.77e-04	182	27	3	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HMGB2 HMGN2 H1-3	1.83e-04	184	27	3	8260e688ec42a1374727bc85dceb7edd19a8b662
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	CHD6 CHD7 PRRC2C	1.86e-04	185	27	3	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	(7)_MNP-(7)_DC_plasmacytoid\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	RRBP1 AEBP1 H1-3	1.86e-04	185	27	3	9f67f652488e17075a372e2a2e1100f6d0af6d7d
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANKRD11 RRBP1 AEBP1	1.86e-04	185	27	3	308a98f111895071d8772bc010554471cc12fab2
ToppCell	droplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGN2	1.86e-04	185	27	3	3dcafbd02b65a2befbb6e6288cb2591e721cddb6
ToppCell	droplet-Marrow-BM-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 HMGN2 H1-3	1.86e-04	185	27	3	4157cc14b06bb99ee67ac1526622cf546e727efc
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SCML2 RRBP1 AEBP1	1.89e-04	186	27	3	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGB2 HMGN2 CHD7	1.89e-04	186	27	3	4fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 HMGB2 H1-3	1.89e-04	186	27	3	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 HMGB2 H1-3	1.89e-04	186	27	3	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SCML2 RRBP1 AEBP1	1.89e-04	186	27	3	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 CHD4 PRRC2C	1.92e-04	187	27	3	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	droplet-Marrow-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 PRAM1 HMGN2	1.95e-04	188	27	3	1526e271411e381eae7a342003002276f83f47a3
ToppCell	MatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)\|MatrixFB / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	1.95e-04	188	27	3	b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 SCML2 TOP2B	1.95e-04	188	27	3	9858940c616e43441644c5a3bea8d832ee4daf79
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGB2 CHD7 H1-3	1.95e-04	188	27	3	33afe31b1093d317dc38c324197c6e91bf6c39d3
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHD6 CHD7 POLR3G	1.95e-04	188	27	3	459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHD6 CHD7 POLR3G	1.95e-04	188	27	3	9fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCell	Fibroblast-E_(Early_Fibroblastic_progenitor)\|World / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	1.95e-04	188	27	3	be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD11 CHD4 RRBP1	2.01e-04	190	27	3	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	HMGB2 HMGN2 H1-3	2.01e-04	190	27	3	165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGB2 HMGN2 TOP2B	2.01e-04	190	27	3	f623f0bdece6002b68ac2207e99408b24a2b1194
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRAM1 HMGB2 HMGN2	2.01e-04	190	27	3	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRAM1 HMGB2 HMGN2	2.04e-04	191	27	3	6c1283d51a845cff67ed5e500f7e944165297b53
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 PRRC2C TOP2B	2.04e-04	191	27	3	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Endothelial-D_(cycle)\|World / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	2.04e-04	191	27	3	49a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCell	Endothelial-Endothelial-D_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	HMGB2 HMGN2 H1-3	2.04e-04	191	27	3	a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HMGB2 HMGN2 H1-3	2.04e-04	191	27	3	ff2cc4c10aa584b3daeaaf23cd8ee09bdbdf684d
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 PRRC2C TOP2B	2.04e-04	191	27	3	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 PRRC2C TOP2B	2.04e-04	191	27	3	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRAM1 CHD6 CTR9	2.08e-04	192	27	3	fcdb2e924800457d21e4aaeeedd81dbf80216eed
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CHD6 RRBP1 PHIP	2.08e-04	192	27	3	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRAM1 HMGB2 HMGN2	2.08e-04	192	27	3	86d561c30554ff04c21801d4aaf8e3c9efe49af4
ToppCell	Non-neuronal-Dividing-Radial_Glia-Low_Quality\|World / Primary Cells by Cluster	HMGB2 HMGN2 H1-3	2.08e-04	192	27	3	5fa5b2f250ec5ad5a232c022266f0cd01ff4a753
ToppCell	COVID-19_Severe-Myeloid_G-immature_Neutrophil\|COVID-19_Severe / Disease group, lineage and cell class	PRAM1 HMGB2 HMGN2	2.08e-04	192	27	3	303deb68da2e4a75e6ee5a79478182a8bc41c7c5
ToppCell	Non-neuronal-Dividing-Radial_Glia-Low_Quality-16\|World / Primary Cells by Cluster	HMGB2 HMGN2 H1-3	2.08e-04	192	27	3	0d6413df15dfecdffc777fb02df3aaf0c30540b1
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRBP1 AEBP1 PRRC2C	2.08e-04	192	27	3	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 PRRC2C TOP2B	2.11e-04	193	27	3	49f4fbec91acda4727703e0e359ed780eefb8a22
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PRAM1 AEBP1 PTHLH	2.11e-04	193	27	3	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	control-pDC\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SCML2 RRBP1 AEBP1	2.11e-04	193	27	3	30a6559c9a9e8941861cb259b4836acccc427e68
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HMGB2 HMGN2 H1-3	2.11e-04	193	27	3	444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HMGB2 HMGN2 H1-3	2.11e-04	193	27	3	ecbe1bd16df547427da5e69a3017300e766c2899
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C TOP2B H1-3	2.14e-04	194	27	3	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HMGB2 HMGN2 H1-3	2.14e-04	194	27	3	6cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HMGB2 HMGN2 H1-3	2.14e-04	194	27	3	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 RRBP1 PRRC2C	2.14e-04	194	27	3	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HMGB2 HMGN2 H1-3	2.14e-04	194	27	3	3590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C TOP2B H1-3	2.14e-04	194	27	3	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Pro-B\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HMGB2 HMGN2 H1-3	2.14e-04	194	27	3	58d7c56d2b9c893b62da2334428d677e3451fe07
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C TOP2B H1-3	2.14e-04	194	27	3	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 CHD4 PRRC2C	2.17e-04	195	27	3	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMGB2 HMGN2 H1-3	2.17e-04	195	27	3	db1660ce74819cd816bdcfcae5efb3aad82cce66
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 CHD4 PRRC2C	2.17e-04	195	27	3	7796ea9247f4c63762f0de8490fed08b9717fa23
Computational	Neighborhood of ANP32B	HMGB2 HMGN2	1.70e-03	37	18	2	GNF2_ANP32B
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	2.74e-03	47	18	2	GAVISH_3CA_METAPROGRAM_B_CELLS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	2.74e-03	47	18	2	GAVISH_3CA_METAPROGRAM_MACROPHAGES_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	2.97e-03	49	18	2	GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	2.97e-03	49	18	2	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	RRBP1 PRRC2C	2.97e-03	49	18	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	2.97e-03	49	18	2	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	3.09e-03	50	18	2	GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	3.09e-03	50	18	2	GAVISH_3CA_MALIGNANT_METAPROGRAM_3_CELL_CYLCE_HMG_RICH
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 HMGN2	3.09e-03	50	18	2	GAVISH_3CA_METAPROGRAM_EPITHELIAL_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HMGB2 TOP2B	3.09e-03	50	18	2	GAVISH_3CA_METAPROGRAM_B_CELLS_PROGENITOR
Drug	etimizol	HMGB2 HMGN2	1.35e-05	5	27	2	CID000006168
Drug	cryptolepine	PHIP TOP2B	6.06e-05	10	27	2	CID000082143
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A	CHD4 RRBP1 PTHLH H1-3	7.24e-05	191	27	4	4303_DN
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ANKRD11 CHD4 PRRC2C H1-3	7.24e-05	191	27	4	6020_DN
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	CHD4 RRBP1 CAMSAP1 H1-3	7.24e-05	191	27	4	3926_DN
Drug	Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; PC3; HT_HG-U133A	ANKRD11 CHD7 ZNF276 H1-3	7.85e-05	195	27	4	4019_DN
Drug	Amidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A	SCML2 PRRC2A PTHLH H1-3	7.85e-05	195	27	4	4481_DN
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A	ANKRD11 CHD4 RRBP1 PRRC2C	7.85e-05	195	27	4	6159_DN
Drug	Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SCML2 RRBP1 SLC4A1AP PRRC2A	8.16e-05	197	27	4	3425_DN
Drug	Trichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A	SCML2 ZNF276 RRBP1 PTHLH	8.32e-05	198	27	4	1797_DN
Drug	ST021200; Down 200; 10uM; MCF7; HT_HG-U133A	CAMSAP1 AEBP1 POLR3G H1-3	8.32e-05	198	27	4	7554_DN
Disease	CHARGE syndrome (implicated_via_orthology)	CHD6 CHD7	1.69e-05	7	27	2	DOID:0050834 (implicated_via_orthology)
Disease	eosinophil measurement	TMEM131 CHD7 RRBP1	1.31e-04	108	27	3	EFO_0803540
Disease	congenital heart disease (implicated_via_orthology)	CHD6 CHD7	1.82e-03	69	27	2	DOID:1682 (implicated_via_orthology)
Disease	Prostatic Neoplasms	HMGB2 CHD6 CHD7 PTHLH	2.25e-03	616	27	4	C0033578
Disease	Malignant neoplasm of prostate	HMGB2 CHD6 CHD7 PTHLH	2.25e-03	616	27	4	C0376358
Disease	age at menopause	CHD6 CHD7 PRRC2A	2.59e-03	302	27	3	EFO_0004704
Disease	albuminuria	CHD7 PRRC2C	3.35e-03	94	27	2	EFO_0004285
Disease	mean fractional anisotropy measurement	ANKRD11 TMEM131	3.42e-03	95	27	2	EFO_0008399
Disease	Hypermetropia	ANKRD11 CHD7	4.00e-03	103	27	2	HP_0000540
Disease	fibrinogen measurement	PRR12 PHIP	4.47e-03	109	27	2	EFO_0004623
Disease	keratinocyte carcinoma	ANKRD11 ZNF276	5.21e-03	118	27	2	EFO_0010176
Disease	cancer	ANKRD11 ZNF276 PTHLH	5.68e-03	400	27	3	MONDO_0004992
Disease	cystatin C measurement	ANKRD11 ZNF276 PDILT	5.76e-03	402	27	3	EFO_0004617
Disease	melanoma	ANKRD11 ZNF276	5.92e-03	126	27	2	EFO_0000756
Disease	skin pigmentation measurement	ANKRD11 ZNF276	6.96e-03	137	27	2	EFO_0007009
Disease	autism spectrum disorder (implicated_via_orthology)	CHD6 CHD7	8.50e-03	152	27	2	DOID:0060041 (implicated_via_orthology)
Disease	eosinophil count	ANKRD11 HMGN2 TMEM131 CHD7 RRBP1	1.03e-02	1488	27	5	EFO_0004842
Disease	mean arterial pressure	PHIP REXO1 PDILT	1.04e-02	499	27	3	EFO_0006340
Disease	autoimmune disease	TMEM131 PRRC2A	1.09e-02	173	27	2	EFO_0005140

Protein segments in the cluster

Peptide	Gene	Start	Entry
PKGKPCPKEIPKESK	ERVK-9	221	Q9UKH3
KPPGLDPPFKDKKLK	ANKRD11	1641	Q6UB99
PPKKGKEKPPKATKK	AEBP1	116	Q8IUX7
PPKATKKPKEKPPKA	AEBP1	146	Q8IUX7
KKPKEKPPKATKKPP	AEBP1	151	Q8IUX7
KPPKATKKPPSGKRP	AEBP1	156	Q8IUX7
QGLGKPKSKPKKPRP	CAMSAP1	1356	Q5T5Y3
KDPKEPKEPKEKKEP	CHD7	651	Q9P2D1
PKEPKEKKEPKEPKT	CHD7	656	Q9P2D1
EKKEPKEPKTPKAPK	CHD7	661	Q9P2D1
PKAPKIPKEPKEKKA	CHD7	671	Q9P2D1
PKGDKKGKKKDPNAP	HMGB2	81	P26583
KGKKKDPNAPKRPPS	HMGB2	86	P26583
KPEPKPKKAPAKKGE	HMGN2	36	P05204
PKKAPAKKGEKVPKG	HMGN2	41	P05204
PKGKPCPKEIPKESK	ERVK-24	111	P61566
PKGKPCPKEIPKESK	ERVK-7	111	P61567
PKPKRKREPKEPKEP	CHD6	116	Q8TD26
PKKRRPPKAEKKKAP	CTR9	981	Q6PD62
PKGKPCPKEIPKESK	ERVK-21	221	P61565
PKGKPCPKEIPKESK	ERVK-5	111	Q9HDB8
PPPTKKKGQKPGRKD	ENO4	201	A6NNW6
PKPKAAKPKSGKPKV	H1-3	196	P16402
GSPRVPDAKKPKPKK	CHD4	276	Q14839
PDAKKPKPKKVAPLK	CHD4	281	Q14839
AKPKGPPVQKKKPKV	PDILT	566	Q8N807
PKEGKPKKKKTGAPP	REXO1	371	Q8N1G1
LKPKKLPKPPAKLPK	STAP2	336	Q9UGK3
PINKGPKPKREKKEP	TOP2B	1296	Q02880
DLPKKPPKPEFGKLK	PRAM1	31	Q96QH2
GKKREDPKPGPKKPK	PRRC2C	1626	Q9Y520
DPKPGPKKPKEKVDA	PRRC2C	1631	Q9Y520
PKPPKPDPLKITKGK	PRRC2A	976	P48634
PTKVKAEPPPKKRKK	PRR12	1786	Q9ULL5
KKKSGSKKKGEPGPP	RRBP1	626	Q9P2E9
KDGPISPKKKKPKER	PHIP	906	Q8WWQ0
PRKKGPNSGKKEKPL	SCML2	306	Q9UQR0
KGKGKPLQRKVKPPK	TMEM131	1381	Q92545
KKPGPKPGWKKKLRC	ZNF276	411	Q8N554
PKPKKAKDAGKGTPL	POLR3G	121	O15318
EQPLKTPGKKKKGKP	PTHLH	116	P12272
ELKKKKTPGPGKLPP	SLC4A1AP	746	Q9BWU0