Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainMIR

RYR2 RYR3 SDF2L1

5.28e-05101453PF02815
DomainMIR_motif

RYR2 RYR3 SDF2L1

5.28e-05101453IPR016093
DomainMIR

RYR2 RYR3 SDF2L1

5.28e-05101453PS50919
DomainMIR

RYR2 RYR3 SDF2L1

5.28e-05101453SM00472
DomainRyanodine_rcpt

RYR2 RYR3

1.79e-0431452IPR003032
DomainRyanrecept_TM4-6

RYR2 RYR3

1.79e-0431452IPR009460
DomainRyR

RYR2 RYR3

1.79e-0431452PF02026
DomainRR_TM4-6

RYR2 RYR3

1.79e-0431452PF06459
DomainRyan_recept

RYR2 RYR3

1.79e-0431452IPR013333
DomainG8_domain

CEMIP PKHD1

3.56e-0441452IPR019316
DomainG8

CEMIP PKHD1

3.56e-0441452PS51484
DomainG8

CEMIP PKHD1

3.56e-0441452SM01225
DomainG8

CEMIP PKHD1

3.56e-0441452PF10162
DomainTSP_3

THBS1 THBS3

5.89e-0451452PF02412
DomainTSP3

THBS1 THBS3

5.89e-0451452PS51234
DomainTSP_CTER

THBS1 THBS3

5.89e-0451452PS51236
DomainThrombospondin_3_rpt

THBS1 THBS3

5.89e-0451452IPR017897
DomainTSP_type-3_rpt

THBS1 THBS3

5.89e-0451452IPR028974
Domain-

THBS1 THBS3

5.89e-04514524.10.1080.10
DomainThrombospondin_C

THBS1 THBS3

5.89e-0451452IPR008859
DomainTSP_C

THBS1 THBS3

5.89e-0451452PF05735
DomainThrombospondin_3-like_rpt

THBS1 THBS3

5.89e-0451452IPR003367
DomainTSPN

THBS1 NELL2 THBS3

7.24e-04231453SM00210
DomainRIH_assoc-dom

RYR2 RYR3

8.80e-0461452IPR013662
DomainPectin_lyas_fold

CEMIP PKHD1

8.80e-0461452IPR012334
Domain-

CEMIP PKHD1

8.80e-04614522.160.20.10
DomainIns145_P3_rec

RYR2 RYR3

8.80e-0461452PF08709
DomainRIH_assoc

RYR2 RYR3

8.80e-0461452PF08454
DomainRIH_dom

RYR2 RYR3

8.80e-0461452IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

8.80e-0461452IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

8.80e-0461452IPR015925
Domain-

RYR2 RYR3

8.80e-04614521.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

8.80e-0461452PF01365
Domain-

LRIT2 LRRN1 SLITRK4 LRRC8D LRGUK LRRC31 LMOD1 CD180 TBCE

9.19e-0432114593.80.10.10
DomainCUB_dom

ADGRB3 ZZEF1 CRHBP CSMD1

1.00e-03571454IPR000859
DomainL_dom-like

LRIT2 LRRN1 SLITRK4 LRRC8D LRGUK LRRC31 LMOD1 CD180 TBCE

1.07e-033281459IPR032675
DomainAPC_su10/DOC_dom

ZZEF1 HERC2

1.23e-0371452IPR004939
DomainDOC

ZZEF1 HERC2

1.23e-0371452PS51284
DomainANAPC10

ZZEF1 HERC2

1.23e-0371452PF03256
DomainAPC10

ZZEF1 HERC2

1.23e-0371452SM01337
DomainLeu-rich_rpt

LRIT2 LRRN1 SLITRK4 LRRC8D LRGUK LRRC31 CD180 TBCE

1.28e-032711458IPR001611
DomainARM-type_fold

DCAF1 ZBTB7C HUWE1 LYST RYR3 PACRGL UTP20 HEATR5B IPO11

1.34e-033391459IPR016024
DomainAnk_2

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

1.47e-032151457PF12796
DomainPectin_lyase_fold/virulence

CEMIP PKHD1

1.63e-0381452IPR011050
DomainK_chnl_volt-dep_Kv1

KCNA5 KCNA7

1.63e-0381452IPR003972
DomainLRR_1

LRIT2 LRRN1 SLITRK4 LRRC8D LRGUK LRRC31 CD180

1.63e-032191457PF00560
DomainIon_trans_dom

SCN11A RYR2 RYR3 KCNA5 KCNA7

1.96e-031141455IPR005821
DomainIon_trans

SCN11A RYR2 RYR3 KCNA5 KCNA7

1.96e-031141455PF00520
DomainAnk

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

2.05e-032281457PF00023
DomainTransglut_N

TGM1 TGM7

2.08e-0391452PF00868
DomainTRANSGLUTAMINASES

TGM1 TGM7

2.08e-0391452PS00547
DomainBPI1

BPIFC BPIFB4

2.08e-0391452SM00328
DomainBPI2

BPIFC BPIFB4

2.08e-0391452SM00329
Domain-

TGM1 TGM7

2.08e-03914523.90.260.10
DomainGln_gamma-glutamylTfrase_euk

TGM1 TGM7

2.08e-0391452IPR023608
DomainTransglutaminase_AS

TGM1 TGM7

2.08e-0391452IPR013808
DomainTransglutaminase_N

TGM1 TGM7

2.08e-0391452IPR001102
DomainLBP_BPI_CETP

BPIFC BPIFB4

2.08e-0391452PS00400
DomainTransglut_C

TGM1 TGM7

2.08e-0391452PF00927
DomainLBP_BPI_CETP_C

BPIFC BPIFB4

2.59e-03101452PF02886
DomainTransglutaminase_C

TGM1 TGM7

2.59e-03101452IPR008958
DomainAnk_3

ANK1 ANKRD23

2.59e-03101452PF13606
DomainTransglutaminase-like

TGM1 TGM7

3.14e-03111452IPR002931
DomainTGc

TGM1 TGM7

3.14e-03111452SM00460
DomainTransglut_core

TGM1 TGM7

3.14e-03111452PF01841
Domain-

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

3.27e-0324814571.25.40.20
DomainANK

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

3.50e-032511457SM00248
DomainANK_REPEAT

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

3.65e-032531457PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

3.73e-032541457IPR020683
DomainANK_REP_REGION

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

3.73e-032541457PS50297
DomainABC_A

ABCA3 ABCA9

3.75e-03121452IPR026082
DomainLipid-bd_serum_glycop_C

BPIFC BPIFB4

3.75e-03121452IPR001124
DomainG_TR_1

EEFSEC GFM2

4.41e-03131452PS00301
Domain-

ACAD9 ACOX1

4.41e-031314521.10.540.10
DomainLBP_BPI_CETP

BPIFC BPIFB4

4.41e-03131452PF01273
DomainAcylCoA_DH/ox_N

ACAD9 ACOX1

4.41e-03131452IPR013786
DomainBPI/LBP/Plunc

BPIFC BPIFB4

4.41e-03131452IPR032942
DomainBactericidal_perm-incr_a/b_dom

BPIFC BPIFB4

4.41e-03131452IPR017943
DomainLipid-bd_serum_glycop_N

BPIFC BPIFB4

4.41e-03131452IPR017942
DomainAnkyrin_rpt

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

4.42e-032621457IPR002110
DomainEGF_CA

THBS1 NELL2 THBS3 HEG1

4.52e-03861454PF07645
DomainLRR

LRIT2 LRRN1 SLITRK4 LRRC8D LRGUK CD180

4.87e-032011456PS51450
DomainWH2

COBL LMOD1

5.12e-03141452SM00246
DomainCys-rich_flank_reg_C

LRIT2 LRRN1 SLITRK4 CD180

5.32e-03901454IPR000483
DomainLRRCT

LRIT2 LRRN1 SLITRK4 CD180

5.32e-03901454SM00082
DomainFERM_M

FRMPD4 PTPN13 MYO15A

5.45e-03461453PF00373
Domain-

LRIT2 TRIM2 LRRN1 DSCAM MXRA8 ADAMTSL3 TGM1 CD3G TRIM67 PKHD1 TGM7 CDON

5.59e-03663145122.60.40.10
DomainBbox_C

TRIM2 TRIM67

5.88e-03151452IPR003649
DomainAcyl-CoA_Oxase/DH_cen-dom

ACAD9 ACOX1

5.88e-03151452IPR006091
DomainBBC

TRIM2 TRIM67

5.88e-03151452SM00502
DomainAcylCoA_DH/oxidase_NM_dom

ACAD9 ACOX1

5.88e-03151452IPR009100
DomainAcyl-CoA_dh_M

ACAD9 ACOX1

5.88e-03151452PF02770
DomainFERM_central

FRMPD4 PTPN13 MYO15A

6.50e-03491453IPR019748
DomainFERM_domain

FRMPD4 PTPN13 MYO15A

6.50e-03491453IPR000299
DomainWH2

COBL LMOD1

6.69e-03161452PF02205
DomainAcylCo_DH/oxidase_C

ACAD9 ACOX1

6.69e-03161452IPR009075
DomainFERM_1

FRMPD4 PTPN13 MYO15A

6.88e-03501453PS00660
DomainFERM_2

FRMPD4 PTPN13 MYO15A

6.88e-03501453PS00661
DomainFERM_3

FRMPD4 PTPN13 MYO15A

6.88e-03501453PS50057
DomainBand_41_domain

FRMPD4 PTPN13 MYO15A

6.88e-03501453IPR019749
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CUL1 ANK1 ACACB RSL1D1 ACAD9 SLITRK4 RYR3 MDN1 MTHFD1 USP32 COBL CDK11B IPO11 DCAF7

4.09e-084971511436774506
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CCP110 RSL1D1 ACAD9 TARS2 NUP54 PTPN13 IGF2R MDN1 OCIAD1 UTP20 HERC2 YIPF6 IPO11 DCAF7

5.76e-067541511433060197
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DIP2B RSL1D1 ADGRB3 VPS16 INO80 FCHO2 THBS1 GPR158 EIF2B2 HERC2 SNRPD1

7.94e-064751511131040226
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

EEFSEC CEP295NL RYR2 RYR3 PTPN13 PNPLA3 SOWAHB

9.32e-06168151730631154
Pubmed

Association of glucokinase regulatory gene polymorphisms with risk and severity of non-alcoholic fatty liver disease: an interaction study with adiponutrin gene.

GCKR PNPLA3

1.87e-052151223800943
Pubmed

Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis.

ITGAM LYST

1.87e-052151221403131
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.87e-05215128898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.87e-052151214550562
Pubmed

Expression and initial characterization of recombinant mouse thrombospondin 1 and thrombospondin 3.

THBS1 THBS3

1.87e-05215128654563
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.87e-052151221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.87e-052151216678258
Pubmed

Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage.

HUWE1 CDC6

1.87e-052151217567951
Pubmed

Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population.

GJB2 MYO15A

1.87e-052151231581539
Pubmed

Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals.

GCKR PNPLA3

1.87e-052151224477042
Pubmed

Thrombospondin 3 is a developmentally regulated heparin binding protein.

THBS1 THBS3

1.87e-05215128288588
Pubmed

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.

UBQLN4 ATXN1

1.87e-052151211001934
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

1.87e-052151214985349
Pubmed

Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.

INO80 SRCAP

1.87e-052151217101442
Pubmed

Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents.

GCKR PNPLA3

1.87e-052151222105854
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

ACOX1 HUWE1 YARS2 MDN1 HERC2

2.08e-0576151527542412
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DIP2B CCP110 KIF26B PRAG1 LYST FAM171A1 PTPN13 MDN1 KCNA7 ATXN1 SYNE2 MIEF1 COBL DCAF7

2.52e-058611511436931259
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DIP2B INTU LRRN1 HUWE1 ZSWIM1 TARS2 LRRC8D JMJD1C KANSL3 PTPN13 SMG7 ATXN1 GPR158 NAT10 PIP5K1A COBL CSMD1 NXPH4 INVS

2.62e-0514891511928611215
Pubmed

Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.

LYST RYR2 TBCE

2.82e-0514151311472062
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

RSL1D1 VPS16 IGF2R USP32 UTP20 CDK11B TBCE

4.16e-05212151733462405
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RSL1D1 HUWE1 SRCAP NUP54 NOP58 IGF2R MDN1 RPAP1 MTHFD1 SYNE2 NAT10 UTP20 HERC2 HEATR5B SNRPD1

4.26e-0510241511524711643
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

RSL1D1 INO80 SRCAP NOP58 IGF2R MTHFD1 SNRPD1 IPO11

5.34e-05300151828561026
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

5.60e-053151218403125
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

5.60e-053151229730765
Pubmed

Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits.

GCKR PNPLA3

5.60e-053151224785259
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

5.60e-05315127876312
Pubmed

Organization and expression of the SLC36 cluster of amino acid transporter genes.

SLC36A1 SLC36A3

5.60e-053151215058382
Pubmed

A cluster of proton/amino acid transporter genes in the human and mouse genomes.

SLC36A1 SLC36A3

5.60e-053151212809675
Pubmed

Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients.

GCKR PNPLA3

5.60e-053151227015186
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

5.60e-053151222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

5.60e-053151210788707
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS3

5.60e-053151234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS3

5.60e-05315121459996
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

5.60e-05315127621815
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS3

5.60e-05315128400410
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

5.60e-053151210473538
Pubmed

The relationship among GNB3 rs5443, PNPLA3 rs738409, GCKR rs780094 gene polymorphisms, type of maternal gestational weight gain and neonatal outcomes (STROBE-compliant article).

GCKR PNPLA3

5.60e-053151231305457
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS3

5.60e-05315129373030
Pubmed

Importin-11 overexpression promotes the migration, invasion, and progression of bladder cancer associated with the deregulation of CDKN1A and THBS1.

THBS1 IPO11

5.60e-053151229602637
Pubmed

Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells.

LYST THBS1

5.60e-053151218757424
Pubmed

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci.

GCKR PNPLA3

5.60e-053151228436986
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

5.60e-053151218434746
Pubmed

Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.

ANK1 LRRN1

5.60e-053151238862513
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

5.60e-05315129204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

5.60e-053151221881589
Pubmed

Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents.

GCKR PNPLA3

5.60e-053151231255630
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

5.60e-053151212213830
Pubmed

Genotypic variation in CYP2E1, GCKR, and PNPLA3 among nonalcoholic steatohepatitis patients of Turkish origin.

GCKR PNPLA3

5.60e-053151239042259
Pubmed

Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey.

GCKR PNPLA3

5.60e-053151223416328
Pubmed

CircTHBS1 promotes trophoblast cell migration and invasion and inhibits trophoblast apoptosis by regulating miR-136-3p/IGF2R axis.

THBS1 IGF2R

5.60e-053151238581244
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

5.60e-05315129242641
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

5.60e-053151215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

5.60e-053151225239916
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

5.60e-053151218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

5.60e-053151211159936
Pubmed

Genetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesity.

GCKR PNPLA3

5.60e-053151230710115
Pubmed

Analysis of genotyping for predicting liver injury marker, procollagen III in persons at risk of non-alcoholic fatty liver disease.

GCKR PNPLA3

5.60e-053151229493856
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

5.60e-05315127959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

5.60e-05315124600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

5.60e-05315127635066
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CUL1 KNTC1 RSL1D1 ACAD9 EEF1E1 HUWE1 FCHO2 HPSE GFM2 NOP58 MDN1 SYNE2 NAT10 EIF2B2 SDF2L1 COBL SNRPD1 IPO11

5.66e-0514401511830833792
Pubmed

HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention.

DCAF1 NUP54 GTF2H1

7.39e-0519151321489275
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

CUL1 DIP2B TARS2 NOP58 MDN1 MTHFD1 NAT10

8.38e-05237151729564676
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 RSL1D1 ACAD9 TARS2 FAM171A1 NOP58 PTPN13 IGF2R MDN1 OCIAD1 RPAP1 SYNE2 NAT10 SDF2L1 PIP5K1A HERC2 ANKRD52 DCAF7

8.51e-0514871511833957083
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

INTU INO80 ADAMTSL3 CEMIP HEG1

8.97e-05103151510574462
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CUL1 MTIF3 DIP2B RSL1D1 ACAD9 HUWE1 TARS2 ZZEF1 GFM2 YARS2 NOP58 MDN1 OCIAD1 RPAP1 SYNE2 NAT10 MIEF1 HERC2

9.18e-0514961511832877691
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

FRMPD4 HUWE1 SRCAP MDN1 HERC2

9.39e-0510415159205841
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ANK1 KIF26B HUWE1 ZZEF1 MDN1 RPAP1 EDAR MTHFD1 AGTR2 PKHD1 UTP20 SERPINA9

9.50e-057361511229676528
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

DCAF1 ACACB TARS2 JMJD1C SMG7 PIP5K1A CDC6

9.55e-05242151734011540
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

INO80 HUWE1 SRCAP ZZEF1 PRAG1 LYST KANSL3 TLNRD1 HEG1 IGF2R MDN1 RPAP1 COBL HERC2 SOWAHB

9.95e-0511051511535748872
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DCAF1 RSL1D1 HUWE1 JMJD1C YARS2 NUP54 NOP58 GTF2H1 MDN1 MTHFD1 NAT10 UTP20 CDK11B DCAF7

1.11e-049891511436424410
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

1.12e-044151223413940
Pubmed

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.

CCP110 HERC2

1.12e-044151237074924
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

1.12e-04415129607712
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS3

1.12e-04415126338048
Pubmed

The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.

LYST RYR2

1.12e-04415129070932
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

1.12e-044151223482488
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

1.12e-044151218206662
Pubmed

Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults.

GCKR PNPLA3

1.12e-044151227752939
Pubmed

Heterogeneity of Hereditary Hearing Loss in Iran: a Comprehensive Review.

GJB2 MYO15A

1.12e-044151227743438
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

1.12e-04415129384575
Pubmed

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.

GCKR PNPLA3

1.12e-044151229648650
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

VPS16 INO80 NOP58 NAA25 GTF2H1 PTPN13 MDN1 NAT10 HERC2 IPO11

1.20e-045331511030554943
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

DIP2B HUWE1 ITGAM MDN1 MTHFD1 SDF2L1 SNRPD1 IPO11

1.38e-04344151830333137
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

CUL1 EEFSEC RSL1D1 MDN1 MTHFD1 NAT10 UTP20

1.56e-04262151736880596
Pubmed

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

DCAF1 CUL1 HUWE1 DCAF7

1.57e-0462151418775313
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

MTIF3 DSCAM ADGRB3 PTPN13 IGF2R COBL CSMD1

1.67e-04265151719240061
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS3

1.86e-045151230622267
Pubmed

Thromboxane A2 receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3.

TBXA2R THBS1

1.86e-045151214963009
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

1.86e-045151223918386
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

THBS1 THBS3

1.86e-045151218467703
Pubmed

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.

CUL1 CDC6

1.86e-045151225557911
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

1.86e-045151219011160
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

1.86e-045151233060591
Pubmed

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.

EEFSEC AGTR2

1.86e-045151228877031
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

DCAF1 CUL1 RSL1D1 ACAD9 EEF1E1 HUWE1 TARS2 YARS2 RPAP1 MTHFD1 WDR87 EIF2B2 PIP5K1A PIPSL SNRPD1 DCAF7

2.40e-0413351511629229926
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

7.83e-053932287
GeneFamilyAnkyrin repeat domain containing

ANKRD29 ANK1 ANKRD23 POTEJ ANKRD52 SOWAHB INVS

2.52e-04242937403
GeneFamilyTransglutaminases

TGM1 TGM7

9.20e-049932773
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRIT2 LRRN1 DSCAM ADAMTSL3 CDON

1.46e-03161935593
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD4 PTPN13 MYO15A

2.17e-03509331293
GeneFamilyATP binding cassette subfamily A

ABCA3 ABCA9

2.29e-0314932805
GeneFamilyBPI fold containing

BPIFC BPIFB4

3.00e-0316932456
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF1 DCAF7

3.80e-0318932498
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZZEF1 HERC2

3.80e-031893291
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

INTU LRRN1 RSL1D1 SLITRK4 ADGRB3 LRRC8D NUP54 NELL2 NOP58 NAA25 HEG1 ZNF605 SMG7 SYNE2 NAT10 ZNF624 UTP20 CDK11B CDC6 IPO11

1.81e-0598914820Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

RSL1D1 NUP54 NAA25 SMG7 NAT10 ZNF624 UTP20 CDC6

2.50e-051691488Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 ANK1 KIF26B RYR2 RYR3 PKHD1 CSMD1 MYO15A

2.15e-0718415082cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 ANK1 KIF26B RYR2 RYR3 PKHD1 CSMD1 MYO15A

2.15e-071841508ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 ANK1 KIF26B RYR2 RYR3 PKHD1 CSMD1 MYO15A

2.15e-0718415082b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9|TCGA-Colorectal / Sample_Type by Project: Shred V9

FRMPD4 ADGRB3 ADAMTSL3 ABCA9 RYR3 KCNA5 CDON

1.16e-061591507f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP1 RGS3 SLC47A2 EDAR SYNE2 PKHD1 COBL

3.29e-061861507b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 GRIN3A

4.20e-061931507c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 GRIN3A

4.35e-06194150783863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRB3 PKD1L3 RYR3 TRIM67 CSMD1 MYO15A CDON

4.50e-061951507d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRB3 PKD1L3 RYR3 TRIM67 CSMD1 MYO15A CDON

4.50e-06195150719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF26B MXRA8 ADGRB3 ABCA9 RYR2 CEMIP THBS1

4.97e-0619815073ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellCD8+_Memory_T_cell-CV-2|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RSL1D1 EEF1E1 NOP58 MTHFD1 SDF2L1 CDC6 SNRPD1

5.14e-0619915071e33d8e2e0d6a54ef6e2e13f986e19fd209275a8
ToppCellCV-Moderate-2|Moderate / Virus stimulation, Condition and Cluster

RSL1D1 EEF1E1 NOP58 MTHFD1 SDF2L1 CDC6 SNRPD1

5.14e-06199150770d6f2a328eec4cb2cecb7cd85859fba9e15c9c8
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 SLC24A4

5.31e-062001507a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 GRIN3A

5.31e-0620015076a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 SLC24A4

5.31e-06200150733b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 GRIN3A

5.31e-0620015078d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 SLC24A4

5.31e-0620015079719fabddc34051949468a7520289e3c750de4f8
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP HEG1 TRIM67 GRIN3A

5.31e-062001507cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DSCAM LRGUK PKHD1 MYO15A SERPINA9

1.73e-05160150641d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 DSCAM LRGUK PKHD1 MYO15A SERPINA9

1.73e-051601506c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellCOVID-CD8-CD8_2|COVID / Condition, Cell_class and T cell subcluster

RYR2 NELL2 CD3G SYNE2 SHOC1 ANKRD52

1.79e-051611506307dcc17475413cd9eb70c27bc447f938ee5723d
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

LRIT2 ANK1 RGR TRIM67 GPR158 GRIN3A

1.79e-0516115065f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

ACOX1 TARS2 TGM1 PIP5K1A CDK11B HEATR5B

2.27e-0516815068697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPSE RGS3 LRRC9 HEG1 PTCH2 PNPLA3

2.59e-051721506f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPSE RGS3 LRRC9 HEG1 PTCH2 PNPLA3

2.59e-0517215066ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCHO2 LYST JMJD1C ABCA9 RYR2 HEG1

2.95e-051761506749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 ABCA9 RYR2 NELL2 LMOD1 PLIN1

3.05e-0517715069ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 ABCA9 RYR2 NELL2 LMOD1 PLIN1

3.05e-051771506016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BPIFC HPSE IL23A SLC47A2 GJB2 SERPINA9

3.35e-05180150618bf8561ad3aa9787d2a8ef942a96f641734c608
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD29 KNTC1 DSCAM TGM1 HEG1 SHOC1

3.79e-051841506c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B CRHBP TRIM67 PKHD1 GRIN3A

3.79e-0518415067f6c8912677764d438ab0555faca344d74c2f483
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD29 KNTC1 DSCAM TGM1 HEG1 SHOC1

3.79e-0518415061ed558a88215b248431c524ea16f13d9022ae98c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 ZBTB7C BRINP1 PRAG1 NELL2 SLC24A4

3.79e-0518415066475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

3.79e-05184150623515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

ZBTB7C UBQLN4 HPSE LYST IGF2R SOWAHB

3.79e-051841506d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JMJD1C RYR2 THBS1 C18orf63 PKHD1 CSMD1

4.02e-05186150623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B CRHBP HEG1 TRIM67 GRIN3A

4.02e-05186150696f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCHO2 LYST RGS3 HEG1 SYNE2 IPO11

4.02e-0518615060ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B CRHBP TRIM67 PKHD1 GRIN3A

4.14e-05187150685f1678338a47d91e296f0620d4887f057eb7e70
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C ADAMTSL3 ABCA9 LMOD1 GRIN3A CDON

4.27e-051881506ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB7C ADAMTSL3 ABCA9 LMOD1 GRIN3A CDON

4.53e-051901506efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGAM HPSE LYST THBS1 SLC24A4 PTCH2

4.66e-0519115065d6ef70cc15ec5e983a953e547e40f9c06e355fb
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

RYR2 NELL2 NOP58 CD3G ATXN1 SYNE2

4.80e-051921506eb4909574fb5fc91399463523e2737095773200a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

4.94e-051931506d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

4.94e-051931506010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B CRHBP HEG1 TRIM67 GRIN3A

4.94e-0519315062189da4b727e25e62669d7b9257f06493be21a27
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FRMPD4 KIF26B ADAMTSL3 PRAG1 EDAR LMOD1

4.94e-051931506000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

4.94e-0519315063ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

4.94e-051931506e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

4.94e-051931506658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF26B PRAG1 EDAR CENPI CDC6

5.08e-051941506590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

5.08e-0519415061bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FRMPD4 KIF26B ADAMTSL3 PRAG1 EDAR LMOD1

5.08e-05194150667f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellCV-Severe-2|CV / Virus stimulation, Condition and Cluster

RSL1D1 EEF1E1 NOP58 MTHFD1 SDF2L1 SNRPD1

5.23e-0519515061cde7f6e6c9c610bacc79014519447112c27dd9d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 DSCAM BRINP1 RYR2 NELL2 CSMD1

5.23e-0519515062e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

RYR2 NELL2 NOP58 CD3G ATXN1 SYNE2

5.38e-05196150630e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANKRD29 ABCA3 PTPN13 SYNE2 PKHD1 COBL

5.53e-0519715063d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS1 THBS3 TRIM67 KCNA5 TIMP4 LMOD1

5.53e-051971506079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

KIF26B ADGRB3 ABCA9 RYR2 CEMIP THBS1

5.53e-051971506fb847f2277609c31fffcdf49517243ce0684facf
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

DCAF1 ADAMTSL3 ITGAM JMJD1C HEG1 CD180

5.69e-051981506af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK1 RYR2 THBS1 GJB2 KCNA5 LMOD1

5.69e-051981506f261a37dd07976548b897af86df1d1a0dc069889
ToppCellCV-Severe-2|Severe / Virus stimulation, Condition and Cluster

RSL1D1 EEF1E1 NOP58 MTHFD1 SDF2L1 SNRPD1

5.69e-051981506254659bb53dc2511c714295c2df1ab1fddb2f867
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 ADGRB3 BRINP1 RYR2 NELL2 CSMD1

5.69e-0519815068ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

MXRA8 ADGRB3 ADAMTSL3 ABCA9 RYR2 LMOD1

5.69e-05198150626e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

DCAF1 ADAMTSL3 ITGAM JMJD1C HEG1 CD180

5.69e-051981506ad39cce004867f083f8da1954e0cf5a263815184
ToppCellSepsis-URO-Lymphocyte-T/NK-CD8+_T_naive|URO / Disease, condition lineage and cell class

ANKRD29 ACACB RSL1D1 NELL2 CD3G CDON

5.69e-051981506c07426d4119b53e58eb5f448ae364f47cac1fc5c
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

DCAF1 ADAMTSL3 ITGAM JMJD1C HEG1 CD180

5.69e-05198150662cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ITGAM THBS1 IGF2R SLC24A4 USP32 CD180

5.85e-0519915064e0b73d88b1345ec63a9e5629762341e75beb47f
ToppCellCV-Moderate-2|CV / Virus stimulation, Condition and Cluster

RSL1D1 EEF1E1 NOP58 MTHFD1 CDC6 SNRPD1

5.85e-0519915062d98424a5247e87f98095c11fb945289092a9d75
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

6.02e-052001506858421b91f5207b7934b5c219752cb9322a3da31
ToppCellNeuronal-Inhibitory|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B CRHBP HEG1 TRIM67 GRIN3A

6.02e-0520015069ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

6.02e-052001506a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 ZBTB7C DSCAM MXRA8 RGR PTPN13

6.02e-052001506f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B CRHBP HEG1 TRIM67 GRIN3A

6.02e-052001506347a510755374c6a66acee326565dfc447993f18
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

LRRN1 ZZEF1 CRHBP PTCH2 GRIN3A NXPH4

6.02e-0520015066f3fe94107fa2a2ded4888780b36700cce48adb7
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANK1 KIF26B ADAMTSL3 CRHBP TRIM67 GRIN3A

6.02e-0520015062131c8e7fa054b79906eaf60536da892438b09cd
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

BANF2 CRHBP RYR3 GPR158 PKHD1

8.79e-051331505a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-5|TCGA-Brain / Sample_Type by Project: Shred V9

LRIT2 RGR TRIM67 SLC24A4 GRIN3A

1.01e-041371505a7c76201b8901b2ef7ebbb4dfe0cec0dc4534ef5
ToppCellControl-Epithelial_alveolar-AT_1-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANKRD29 LRRN1 LRRC9 TGM1 COBL

1.20e-04142150594e277f038f4006d99ff50222b0f5cf89bc3d46d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCAF1 LRRN1 THBS1 MYO15A PLIN1

1.20e-041421505d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCAF1 LRRN1 THBS1 MYO15A PLIN1

1.20e-041421505a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellASK454-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

JMJD1C GTF2H1 ZNF605 USP32 UTP20

1.28e-0414415058e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 EDAR WDR87 CENPI CDC6

1.70e-041531505d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 EDAR WDR87 CENPI CDC6

1.70e-04153150554a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 EDAR WDR87 CENPI CDC6

1.70e-04153150569a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 EDAR WDR87 CENPI CDC6

1.70e-041531505e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Efhd2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

RGR EDAR WDR87 CDC6

1.70e-0482150493b75f8822ffe8870195cd1fe0a7286478f61e79
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM H1-7 PRAG1 CD3G CDON

1.80e-041551505c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

SLITRK4 MXRA8 NELL2 GJB2 PIP5K1A

1.80e-04155150585eb60d285b8bfc095c341ae90c0e3b7e7dca9c1
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM H1-7 PRAG1 CD3G CDON

1.80e-0415515059cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

GJB2 SMG7 TIMP4 ZNF624 CD180

1.80e-04155150515bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EEFSEC CCP110 ANK1 ADGRB3 RYR3

1.86e-041561505895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

ZBTB7C ACACB IL23A ZNF624 CSMD1

1.97e-04158150573f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-2|TCGA-Mesothelium / Sample_Type by Project: Shred V9

ACACB FPGT PKD1L3 KANSL3 COBL

2.09e-041601505d288b0a315f6adc0be4bdc89fa67bf93679a743f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF26B CEP295NL ITGAM LYST SLC24A4

2.15e-0416115053a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK1 SYNE2 CD180 SERPINA9 MAP4K2

2.21e-0416215053e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 ACACB DSCAM RYR3 CENPI

2.27e-041631505b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 ACACB DSCAM RYR3 CENPI

2.27e-041631505c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM RGR ABCA9 RYR2 CSMD1

2.41e-0416515056d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM RGR ABCA9 RYR2 CSMD1

2.41e-04165150584f5597b1bb75f42de9a224196bb8ac198bbe3bf
DrugThioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT_HG-U133A

TRIM2 ACACB DSCAM GCKR SRCAP ITGAM CEMIP ATXN1 CDON

2.46e-0617714894164_UP
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

7.27e-0531462DOID:3529 (implicated_via_orthology)
Diseaselung adenocarcinoma (implicated_via_orthology)

GJB2 IGF2R

7.27e-0531462DOID:3910 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

7.27e-0531462DOID:8545 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in large VLDL percentage

BANF2 GCKR JMJD1C PNPLA3

1.73e-04561464EFO_0022250
Diseaselow density lipoprotein particle size measurement

BANF2 GCKR NAA25 PNPLA3

1.98e-04581464EFO_0008593
Diseasefibrinogen measurement, factor VII measurement

DIP2B GCKR PKD1L3 JMJD1C

1.98e-04581464EFO_0004619, EFO_0004623
Diseaseskin aging measurement

PKD1L3 SLC24A4 EDAR SYNE2 EIF2B2 SLC36A3

2.92e-041811466EFO_0008006
Disease2-myristoyl-GPC (14:0) measurement

GCKR SNRPD1

3.60e-0461462EFO_0800242
Disease1-myristoyl-GPC (14:0) measurement

GCKR SNRPD1

3.60e-0461462EFO_0800221
Diseasecreatinine measurement

EEFSEC INTU DSCAM KIF26B GCKR INO80 PKD1L3 SLC47A2 CEMIP THBS3 IGF2R USP32 PKHD1 PIP5K1A

4.38e-0499514614EFO_0004518
Diseasetea consumption measurement

RGS3 NAA25 SLC35D3 PKHD1 CSMD1

4.66e-041291465EFO_0010091
Diseaseurate measurement

UBQLN4 GCKR JMJD1C CEMIP THBS1 NOP58 THBS3 NAA25 PKHD1 PNPLA3 HEATR5B ANKRD52 MAP4K2

5.25e-0489514613EFO_0004531
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ACACB BANF2 GCKR JMJD1C IGF2R SYNE2 PNPLA3

6.38e-042911467EFO_0008317, EFO_0020946
Diseasevisceral adipose tissue measurement

KNTC1 SCN11A UBQLN4 PKD1L3 ZZEF1 HEG1 ATXN1 GPR158 PKHD1

6.81e-044811469EFO_0004765
Diseasechronic kidney disease, diabetic nephropathy

EEF1E1 PTPN13 SLC24A4

7.52e-04361463EFO_0000401, EFO_0003884
Diseaseresponse to lamotrigine

GRIN3A CSMD1

8.56e-0491462EFO_0007661
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

BANF2 GCKR ITGAM JMJD1C IGF2R SYNE2

8.57e-042221466EFO_0008317, EFO_0020943
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

BANF2 GCKR ITGAM JMJD1C IGF2R PNPLA3

9.19e-042251466EFO_0008317, EFO_0020947
Diseaseuric acid measurement

INTU DSCAM BANF2 GCKR CEMIP NAA25 PNPLA3 ANKRD52 MAP4K2 IPO11

9.51e-0461014610EFO_0004761
Diseasecholelithiasis

GCKR FCHO2 JMJD1C PNPLA3

9.72e-04881464EFO_0004799
DiseaseFEV/FEC ratio

EEFSEC ABCA3 BANF2 EEF1E1 BRINP1 ADAMTSL3 JMJD1C NELL2 THBS3 RPAP1 SYNE2 LMOD1 CSMD1 MYO15A CDON

1.16e-03122814615EFO_0004713
Diseasehemoglobin A1 measurement

DCAF1 ZBTB7C ANK1 GCKR JMJD1C THBS3 NAA25 SYNE2 MAP4K2

1.17e-035201469EFO_0007629
Diseasetriglycerides in large LDL measurement

GCKR IGF2R SYNE2

1.27e-03431463EFO_0022319
Diseasepigmentation disease (is_implicated_in)

SLC24A4 HERC2

1.30e-03111462DOID:10123 (is_implicated_in)
DiseaseDiabetic Cardiomyopathies

RYR2 AGTR2

1.30e-03111462C0853897
Diseaselevel of Ceramide (d40:1) in blood serum

GCKR SYNE2

1.30e-03111462OBA_2045185
Diseasepro‐interleukin‐16 measurement

ADAMTSL3 SLC24A4

1.30e-03111462EFO_0010629
Diseasecoffee consumption measurement, tea consumption measurement

GCKR JMJD1C SLC35D3

1.35e-03441463EFO_0006781, EFO_0010091
Diseaseglutamine measurement

GCKR GTF2H1 SLC36A3 PNPLA3

1.40e-03971464EFO_0009768
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

ACACB GCKR IGF2R SYNE2 MAP4K2

1.45e-031661465EFO_0004530, EFO_0004611
Diseasefibrinogen measurement, tissue plasminogen activator measurement

DIP2B PKD1L3 JMJD1C

1.45e-03451463EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

DIP2B PKD1L3 JMJD1C

1.45e-03451463EFO_0004623, EFO_0004792
Diseasecholesterol to total lipids in large VLDL percentage

BANF2 GCKR JMJD1C

1.45e-03451463EFO_0022236
Diseasefatty acid measurement

ACACB GCKR PRAG1 JMJD1C NAA25 IGF2R PNPLA3 MAP4K2

1.53e-034361468EFO_0005110
Diseasehair colour measurement, hair morphology measurement

SLC24A4 HERC2

1.55e-03121462EFO_0007821, EFO_0007822
Diseasetriacylglycerol 44:1 measurement

DSCAM CSMD1

1.55e-03121462EFO_0010399
Diseaselevel of Phosphatidylcholine (14:0_18:1) in blood serum

GCKR SNRPD1

1.55e-03121462OBA_2045062
Diseasenon-alcoholic steatohepatitis

GCKR PNPLA3

1.55e-03121462EFO_1001249
Diseasealpha fetoprotein measurement

GCKR JMJD1C PNPLA3 SERPINA9

1.56e-031001464EFO_0010583
DiseaseDrugs used in diabetes use measurement

MTIF3 ANK1 GCKR ZZEF1 JMJD1C RPAP1

1.74e-032551466EFO_0009924
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

GCKR JMJD1C SYNE2 PNPLA3

1.74e-031031464EFO_0008595, EFO_0020944
Diseasesodium measurement

BRINP1 GCKR JMJD1C PKHD1

1.74e-031031464EFO_0009282
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

PKHD1 CSMD1

1.83e-03131462EFO_0000707, EFO_0004193, EFO_0007932
DiseaseMental Retardation, X-Linked Nonsyndromic

HUWE1 AGTR2

1.83e-03131462C3501611
Diseasecholesteryl esters to total lipids in small VLDL percentage

BANF2 GCKR JMJD1C

1.85e-03491463EFO_0022256
Diseasecognitive function measurement

KNTC1 FRMPD4 DSCAM EEF1E1 BRINP1 FPGT PKD1L3 ADAMTSL3 JMJD1C RGS3 RYR3 CEMIP ATXN1 PKHD1 SOWAHB TBCE

2.02e-03143414616EFO_0008354
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

BANF2 GCKR JMJD1C IGF2R SYNE2 PNPLA3

2.07e-032641466EFO_0008317, EFO_0020944
Diseasecholesterol to total lipids in small VLDL percentage

BANF2 GCKR JMJD1C

2.08e-03511463EFO_0022242
Diseasedystonia (is_implicated_in)

VPS16 NUP54

2.13e-03141462DOID:543 (is_implicated_in)
Diseasenephroblastoma (is_implicated_in)

IGF2R TIMP4

2.13e-03141462DOID:2154 (is_implicated_in)
Diseasetriacylglycerol 46:2 measurement

GCKR CSMD1

2.13e-03141462EFO_0010402
Diseasetriacylglycerol 52:1 measurement

GCKR CSMD1

2.13e-03141462EFO_0010413
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

GCKR IGF2R SYNE2 PNPLA3

2.29e-031111464EFO_0004530, EFO_0008595
Diseasetriglycerides to total lipids in very large VLDL percentage

BANF2 GCKR JMJD1C

2.32e-03531463EFO_0022340
Diseasecholesteryl esters to total lipids in very large VLDL percentage

BANF2 GCKR JMJD1C

2.32e-03531463EFO_0022258
Diseasecholesterol to total lipids in very large VLDL percentage

BANF2 GCKR JMJD1C

2.45e-03541463EFO_0022244
Diseaseliver volume

GCKR JMJD1C

2.45e-03151462EFO_0600048
Diseasetriglycerides in LDL measurement

GCKR IGF2R SYNE2

2.72e-03561463EFO_0022320
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

DIP2B GCKR PKD1L3

2.72e-03561463EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseaseliver fat measurement, liver disease biomarker

GCKR PNPLA3

2.79e-03161462EFO_0006845, EFO_0010821
DiseasePsoriasis

IL23A GJB2 CSMD1

2.86e-03571463C0033860
Diseasefree cholesterol to total lipids in medium VLDL percentage

BANF2 GCKR JMJD1C

2.86e-03571463EFO_0022284
DiseasePustulosis of Palms and Soles

IL23A GJB2 CSMD1

2.86e-03571463C0030246
Diseaseglycoprotein measurement

GCKR PKD1L3 PRAG1 PNPLA3

2.94e-031191464EFO_0004555
Diseasetriglycerides to total lipids in small VLDL percentage

BANF2 GCKR JMJD1C

3.00e-03581463EFO_0022338
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

GCKR JMJD1C SYNE2 PNPLA3

3.12e-031211464EFO_0008595, EFO_0020943
Diseasefasting blood glucose measurement

DSCAM GCKR JMJD1C SLC24A4 CSMD1 MAP4K2

3.13e-032871466EFO_0004465
Diseasetriacylglycerol 48:1 measurement

GCKR CSMD1

3.15e-03171462EFO_0010404
Diseasefree cholesterol to total lipids in very large VLDL percentage

BANF2 GCKR JMJD1C

3.15e-03591463EFO_0022289
Diseasetotal lipids in VLDL measurement

GCKR JMJD1C IGF2R

3.30e-03601463EFO_0022314
Diseasecholesterol to total lipids in IDL percentage

GCKR JMJD1C PNPLA3

3.30e-03601463EFO_0022233
Diseaseacne

FCHO2 PRAG1 EDAR PNPLA3

3.51e-031251464EFO_0003894
Diseasepuberty onset measurement

GCKR JMJD1C KCNA7 HERC2

3.51e-031251464EFO_0005677
Diseasecutaneous melanoma, hair color

SLC24A4 SYNE2 HERC2

3.63e-03621463EFO_0000389, EFO_0003924
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB GCKR IGF2R SYNE2 MAP4K2

3.68e-032061465EFO_0004612, EFO_0020947
Diseasetriglycerides to total lipids in medium VLDL percentage

BANF2 GCKR JMJD1C

3.79e-03631463EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

BANF2 GCKR JMJD1C

3.79e-03631463EFO_0022239
Diseasefish consumption measurement

ADGRB3 NAA25 ATXN1

3.97e-03641463EFO_0010139
Diseasecholesteryl esters to total lipids in medium VLDL percentage

BANF2 GCKR JMJD1C

3.97e-03641463EFO_0022253
Diseasecystatin C measurement

INTU GCKR CEMIP NAA25 RPAP1 EDAR PKHD1

3.98e-034021467EFO_0004617
Diseasewhite matter hyperintensity measurement

ACOX1 FCHO2 PRAG1 GFM2 KCNA5 SHOC1

4.01e-033021466EFO_0005665
Diseasecholesterol in large VLDL measurement

GCKR JMJD1C IGF2R

4.14e-03651463EFO_0021902
Diseasetriacylglycerol 46:1 measurement

GCKR CSMD1

4.36e-03201462EFO_0010401
Diseasecommon carotid intimal medial thickness

PRAG1 RYR3 CD180

4.51e-03671463EFO_0004860
Diseasealkaline phosphatase measurement

TRIM2 ACACB BANF2 GCKR FCHO2 PKD1L3 PRAG1 JMJD1C NOP58 EIF2B2 MIEF1 MAP4K2

4.69e-03101514612EFO_0004533
Diseasefatty acid measurement, linoleic acid measurement

GCKR NAA25 PNPLA3

4.70e-03681463EFO_0005110, EFO_0006807
Diseasesynophrys measurement

SLC24A4 EDAR HERC2

4.70e-03681463EFO_0007906
Diseasesaturated fatty acids to total fatty acids percentage

GCKR PNPLA3

4.80e-03211462EFO_0022305
Diseaseprothrombin time measurement

GCKR JMJD1C

4.80e-03211462EFO_0008390
Diseasefree cholesterol to total lipids in chylomicrons and extremely large VLDL percentage

GCKR PNPLA3

4.80e-03211462EFO_0022277
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

BANF2 GCKR JMJD1C IGF2R

4.86e-031371464EFO_0004611, EFO_0008591
Diseasesusceptibility to mononucleosis measurement

CUL1 RYR2 MDN1

4.90e-03691463EFO_0008403
Diseasebreast size

GCKR LMOD1 CDON

4.90e-03691463EFO_0004884

Protein segments in the cluster

PeptideGeneStartEntry
KLGTLAEGSLQLHLQ

CEP295NL

476

Q96MC4
LLQGTLAQSIKGNHL

CD3G

16

P09693
HSQLVNKLLVAGATV

ANKRD23

156

Q86SG2
SHKNSVLSQGGVALV

CSMD1

331

Q96PZ7
VLLQSTESKLHLQGL

BRINP1

216

O60477
FLGSVLTLLQKQHAL

BPIFB4

426

P59827
ILILVGQTQTHNKSI

ADGRB3

926

O60242
LGHSGAGKTTLLNIL

ABCA9

516

Q8IUA7
AAQQGHTDIVTLLLK

ANK1

741

P16157
IIGSLSNAIKEIHLQ

FCHO2

216

Q0JRZ9
TLAAHQAIGLKGIIL

ACAD9

141

Q9H845
SKNITSGLHFGLVNI

AGTR2

11

P50052
TLGILKNGTSALHAA

ANKRD29

236

Q8N6D5
ITVLLGHNGAGKTTT

ABCA3

561

Q99758
QLVTQVHVLGAAGLK

CAPN5

516

O15484
SNLLLSHAGILKVGD

CDK11B

566

P21127
LQTILGGVNKHSTSI

GJB2

6

P29033
GHLETVNLLLNKGAS

ANKRD52

151

Q8NB46
LQQGIGLHKALSTGL

ATXN1

71

P54253
SLKHLFLIQTGISNL

CD180

126

Q99467
VHIGQGKTLLLTSSA

CEMIP

56

Q8WUJ3
LGRVNLVSGHVKTQL

DCAF7

156

P61962
SLLVTGKIVDHVNGT

NXPH4

121

O95158
LGSVALTVLGIHLNK

SLC24A4

566

Q8NFF2
THAKVQGAGQLRLSI

RGS3

131

P49796
GLGKTVQSIALLAHL

INO80

546

Q9ULG1
HGILLITKVFLGQSV

LRRC9

546

Q6ZRR7
VNNVLLSLSGKSTHI

MAP4K2

536

Q12851
HIILTGASALNKVLG

ACACB

1956

O00763
LNLAKHAASTVQILG

NOP58

306

Q9Y2X3
NHLISKGLGETATVL

DCAF1

856

Q9Y4B6
KSGLGLVHQEGSQLT

FAM171A1

256

Q5VUB5
GKTSLVQLLAHLTGH

MDN1

2071

Q9NU22
LKVLLHSLGLVGNSV

MDN1

2326

Q9NU22
VTLKQTHLNSGVILS

NELL2

91

Q99435
NSIGKSNLVISLHVQ

LRIT2

331

A6NDA9
GVQLLAVSHVGIKLL

MYO15A

2786

Q9UKN7
ISLIGQGKTSDHLIF

GPR158

556

Q5T848
GLGSILLNSLKQTVV

HERC2

856

O95714
KITHLSTLQVGSLNV

HAGH

136

Q16775
TLIHLVQGLGADSKN

IPO11

626

Q9UI26
LGNVILALVNGSKHI

KIF26B

736

Q2KJY2
VVHSLLKGENIGITS

JMJD1C

246

Q15652
KELSGQGHLATALII

EDAR

176

Q9UNE0
TLRKELILSSNIGQH

MTIF3

156

Q9H2K0
SLNLDSNHITGKGIL

LMOD1

391

P29536
VHQLISGKIGISLTR

PNPLA3

106

Q9NST1
LLASVIQTGHLAKLQ

LRRC31

441

Q6UY01
GIHISQTKQLFLEGS

DIP2B

911

Q9P265
GNLHLIHVTSKQTLL

KNTC1

106

P50748
HLSLANNKITTINGL

LRGUK

241

Q96M69
IAVQTTAGKQLSLTH

HEG1

871

Q9ULI3
ALGHLTASQLTNVIL

MIEF1

376

Q9NQG6
SQLVLQAISTHKGLT

H1-7

61

Q75WM6
GSQLGLSVLSKLSQL

HUWE1

926

Q7Z6Z7
TSSALKGAIQLGITH

PIP5K1A

81

Q99755
KGAIQLGITHTVGSL

PIP5K1A

86

Q99755
HGLLSKSVQLNGLTL

HPSE

486

Q9Y251
LLLGIGLQHKSVDQL

NAT10

866

Q9H0A0
ALKGAIQLGITHTVG

PIPSL

31

A2A3N6
IQLGITHTVGSLSTK

PIPSL

36

A2A3N6
LLTQNNSKFHLGSII

GRIN3A

281

Q8TCU5
LLGGVAHTLQKTLQT

PLIN1

331

O60240
LNTVSTGAHVLLGKI

GCKR

486

Q14397
QVTSSSLLLNGKQIH

INTU

361

Q9ULD6
ESLHKVLGGNQTLTV

NUP54

211

Q7Z3B4
LITQGLISKGILSSH

OCIAD1

56

Q9NX40
QKLGKSGHLQVNTTL

RGR

201

P47804
GKTSNHAIVLAQLIT

ACOX1

181

Q15067
IGSGQHLKTSVSILL

HEATR5B

926

Q9P2D3
HSKGLQILGKTLQAS

KCNA5

416

P22460
LSRHSKGLQILGQTL

KCNA7

291

Q96RP8
VGIKALTNHGTANIS

BPIFC

101

Q8NFQ6
GISHELAINLVTKGI

BANF2

26

Q9H503
KISDLTLGHVNGLQL

CRHBP

216

P24387
KHQQLLGEVLTQLSS

CUL1

726

Q13616
GISHVINTKTNLVAL

FRMPD4

446

Q14CM0
KIHQGTLTILSLNSS

CDON

76

Q4KMG0
KGLQDQIVSLGATVH

CDON

316

Q4KMG0
NTLIGTLNVHTVFLK

COBL

121

O75128
VGQLHASLLGLSQLL

IL23A

121

Q9NPF7
LSNSHLVLIGIANTL

CDC6

306

Q99741
NKVTHGLVTVEGQLT

CCP110

471

O43303
SLGKLELQHISSINV

LYST

1061

Q99698
IHQLLTNGGLAKLAS

KANSL3

826

Q9P2N6
QESLHKLLTSGGLNE

EIF2B2

106

P49770
QGLQGLKLFIRSSVH

CENPI

726

Q92674
ILSSVTHNGKQLVLT

RYR2

4756

Q92736
THNGKQLVLTVGLLA

RYR2

4761

Q92736
KSTTTIGLVQALGAH

MTHFD1

386

P11586
NLTGKGITQILGKSH

C18orf63

571

Q68DL7
FHLLKGTSLNVVVLN

FPGT

351

O14772
LVIHNDGTKLLVLNS

LRRC8D

616

Q7L1W4
KEVGLANLTQLTTLH

LRRN1

111

Q6UXK5
HLVKLVLGNLSGTDQ

PTPN13

171

Q12923
LQKLEQHGGSGSLSI

PACRGL

221

Q8N7B6
LSGHVSTVKLLLENN

INVS

366

Q9Y283
LTGLTTIAAHLVKQA

EEF1E1

41

O43324
GRIQVLSNGSLLIKH

DSCAM

741

O60469
TGDVQVLGLVHTQKL

IGF2R

2051

P11717
RHTGQIGGLKLLSNS

TARS2

246

Q9BW92
LHLGSNQITVIKGDV

SLITRK4

406

Q8IW52
GILNSLEIVLKNISH

UTP20

1096

O75691
IAHGVFSGSLNILLK

SLC35D3

16

Q5M8T2
SLTAGNIALTVGLKH

GFM2

426

Q969S9
VLGTLISILKNQLGH

SLC47A2

381

Q86VL8
LNKTETGALVLHNIG

SYNE2

2481

Q8WXH0
TAVISIGNQLLHLKE

SYNE2

5006

Q8WXH0
GSAGLLQQILSLKVV

TMEM170A

11

Q8WVE7
SVLIVGQHILKNGLS

YARS2

446

Q9Y2Z4
ALGLHLQAALTASKV

PTCH2

131

Q9Y6C5
LGIISNKQTHTSAIV

SMG7

126

Q92540
QRLKSHLGTLGLTQG

PKD1L3

1081

Q7Z443
HLASANGNSGVVKLL

POTEJ

141

P0CG39
LNKIEGLTLTVLHSN

SHOC1

761

Q5VXU9
KALTSGAALHVLLSQ

SLC26A10

151

Q8NG04
LDTNTSILNLLHIKG

PKHD1

1956

P08F94
LTVGAQGHVLLLRSQ

ITGAM

601

P11215
GLGKTIQTISLLAHL

SRCAP

646

Q6ZRS2
GHQGVIKLLVQRLAS

SOWAHB

681

A6NEL2
QTLIHLLKCNIGTGL

SLC36A3

46

Q495N2
AHSVTKTQILQGLGF

SERPINA9

86

Q86WD7
KTQILQGLGFNLTHT

SERPINA9

91

Q86WD7
SSLNLKGVQIHTSVV

ERVK-9

706

P63128
AKIQLQLVLHAGDTT

GTF2H1

61

P32780
GKGCITLSQLTLHQR

ZNF624

786

Q9P2J8
GATVGVLLDLNKHTL

TRIM67

716

Q6ZTA4
QLFVGLKVHLSTGEL

EEFSEC

501

P57772
GTLDLSLTVQGKQHV

THBS1

126

P07996
AVTITLNSKLLGGNI

YIPF6

131

Q96EC8
QTLIHLLKGNIGTGL

SLC36A1

51

Q7Z2H8
GQAVRLTHVLTGKNL

SDF2L1

101

Q9HCN8
IVALTAGTKTLQHNL

SLC35A5

161

Q9BS91
GTLSVLKVLVLNQTG

TBCE

201

Q15813
HGIKTVSQIISLQTL

RSL1D1

121

O76021
LRTILSSVTHNGKQL

RYR3

4656

Q15413
SSVTHNGKQLVLTVG

RYR3

4661

Q15413
LHDTVTTLILGGHNK

VPS16

696

Q9H269
TTLILGGHNKRAEQL

VPS16

701

Q9H269
TKGLSILTHDVQSQL

TLNRD1

86

Q9H1K6
LTGQVLSDGKVFIHL

TIMP4

116

Q99727
TIELKNGTQVHGTIT

SNRPD1

16

P62314
ALLSLLNTLAQIHKG

RPAP1

896

Q9BWH6
HSILGEQTKALVTQL

THBS3

221

P49746
LQLHGLLSNISSKEG

PRAG1

936

Q86YV5
TLTITAGNVKHILNA

ZBTB7C

96

A1YPR0
QLKHTNIFTLLVLVG

ZZEF1

2236

O43149
TLNTLIKIIGNSVGA

SCN11A

686

Q9UI33
LLNVSGHVKESGQVL

TGM1

666

P22735
LGLLVTGTIVVSQHA

TBXA2R

76

P21731
LAVVQKSTHLIGSGS

ZSWIM1

346

Q9BR11
EGLKKSIHNLGTILT

TRIM2

306

Q9C040
IQSSKLLLHQIIHTG

ZNF623

441

O75123
AKDLGTLVAGHTLQI

TGM7

656

Q96PF1
TLNQHGIKDGLTVHL

UBQLN4

66

Q9NRR5
IGIHSRTSLLQLTQK

WDR87

981

Q6ZQQ6
GKIFNSSINIVHVGL

ZNF605

76

Q86T29
TSKGLHFNNLIVGLV

USP32

71

Q8NFA0
NALGKAVATSVLHLL

ADAMTSL3

1371

P82987
KLVLLQSSAVLLHSG

MXRA8

11

Q9BRK3
GLQTLISNVVDHIKG

NAA25

896

Q14CX7