Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	NAD transmembrane transporter activity	SLC25A52 SLC25A51	1.04e-04	5	65	2	GO:0051724
GeneOntologyMolecularFunction	protein-lysine 6-oxidase activity	LOX LOXL1	1.04e-04	5	65	2	GO:0004720
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DHX36 DDX55 PIF1 DHX8	1.34e-04	80	65	4	GO:0008186
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	4.62e-04	10	65	2	GO:0001849
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 SMC1A RNF213 IDE DDX55 PIF1 DHX8	5.64e-04	441	65	7	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	DHX36 SMC1A RNF213 IDE DDX55 PIF1 KIF11 DHX8	8.23e-04	614	65	8	GO:0140657
GeneOntologyMolecularFunction	G-quadruplex DNA binding	DHX36 PIF1	9.26e-04	14	65	2	GO:0051880
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	LOX LOXL1	1.22e-03	16	65	2	GO:0016641
GeneOntologyMolecularFunction	helicase activity	DHX36 DDX55 PIF1 DHX8	1.76e-03	158	65	4	GO:0004386
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors	LOX LOXL1	1.91e-03	20	65	2	GO:0016638
GeneOntologyMolecularFunction	copper ion binding	LOX LOXL1 ACR	2.10e-03	78	65	3	GO:0005507
GeneOntologyMolecularFunction	RNA helicase activity	DHX36 DDX55 DHX8	2.10e-03	78	65	3	GO:0003724
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DHX36 DDX55 PIWIL3 FDXACB1 PIF1 DHX8	2.34e-03	417	65	6	GO:0140098
GeneOntologyMolecularFunction	collagen binding	LOX CSPG4 TNXB	2.34e-03	81	65	3	GO:0005518
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	2.98e-03	25	65	2	GO:0001846
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC25A52 SLC25A51	3.22e-03	26	65	2	GO:0000295
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL6A3 LTBP1 FGG TNXB	3.29e-03	188	65	4	GO:0005201
GeneOntologyMolecularFunction	carbohydrate binding	GUSB ACR OS9 C4A C4B	3.37e-03	310	65	5	GO:0030246
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DHX36 SMC1A GNL2 RNF213 IDE DDX55 PIF1 DHX8	3.55e-03	775	65	8	GO:0017111
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC25A52 SLC25A51	4.00e-03	29	65	2	GO:0015216
GeneOntologyMolecularFunction	complement binding	C4A C4B	4.86e-03	32	65	2	GO:0001848
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	SLC25A52 SLC25A51	5.16e-03	33	65	2	GO:0015215
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX36 SMC1A GNL2 RNF213 IDE DDX55 PIF1 DHX8	5.71e-03	839	65	8	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX36 SMC1A GNL2 RNF213 IDE DDX55 PIF1 DHX8	5.75e-03	840	65	8	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX36 SMC1A GNL2 RNF213 IDE DDX55 PIF1 DHX8	5.75e-03	840	65	8	GO:0016818
GeneOntologyBiologicalProcess	mitochondrial NAD transmembrane transport	SLC25A52 SLC25A51	9.48e-06	2	64	2	GO:1990549
GeneOntologyBiologicalProcess	NAD transmembrane transport	SLC25A52 SLC25A51	9.42e-05	5	64	2	GO:0035352
GeneOntologyBiologicalProcess	peptidyl-lysine oxidation	LOX LOXL1	9.42e-05	5	64	2	GO:0018057
GeneOntologyBiologicalProcess	aorta development	MEGF8 LOX LOXL1 LTBP1	1.12e-04	80	64	4	GO:0035904
GeneOntologyBiologicalProcess	NAD transport	SLC25A52 SLC25A51	1.41e-04	6	64	2	GO:0043132
GeneOntologyCellularComponent	blood microparticle	C1R C4A C4B FGG GSN	9.22e-05	144	66	5	GO:0072562
GeneOntologyCellularComponent	mitotic cohesin complex	SMC1A STAG2	2.04e-04	7	66	2	GO:0030892
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	2.72e-04	8	66	2	GO:0106139
GeneOntologyCellularComponent	other organism part	C4A C4B	3.48e-04	9	66	2	GO:0044217
GeneOntologyCellularComponent	cohesin complex	SMC1A STAG2	5.30e-04	11	66	2	GO:0008278
HumanPheno	Hyperextensible skin	RAF1 NEPRO MEGF8 C1R LTBP1 TNXB GSN	2.50e-05	162	29	7	HP:0000974
HumanPheno	Abnormal elasticity of skin	RAF1 NEPRO MEGF8 LOX C1R LTBP1 TNXB GSN	3.69e-05	238	29	8	HP:0010647
HumanPheno	Bruising susceptibility	RAF1 LOX HPS6 C1R FGG TNXB GSN	4.60e-05	178	29	7	HP:0000978
HumanPheno	Abnormally lax or hyperextensible skin	RAF1 NEPRO MEGF8 C1R LTBP1 TNXB GSN	4.77e-05	179	29	7	HP:0008067
HumanPheno	Subcutaneous hemorrhage	RAF1 LOX HPS6 C1R C4A FGG TNXB GSN	6.58e-05	258	29	8	HP:0001933
Domain	Lysyl_oxidase	LOX LOXL1	1.22e-04	5	66	2	IPR001695
Domain	Anaphylatoxin_comp_syst	C4A C4B	1.22e-04	5	66	2	IPR018081
Domain	LYSYL_OXIDASE	LOX LOXL1	1.22e-04	5	66	2	PS00926
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	1.22e-04	5	66	2	IPR001840
Domain	Lysyl_oxidase_CS	LOX LOXL1	1.22e-04	5	66	2	IPR019828
Domain	Lysyl_oxidase	LOX LOXL1	1.22e-04	5	66	2	PF01186
Domain	ANATO	C4A C4B	2.55e-04	7	66	2	SM00104
Domain	ANATO	C4A C4B	2.55e-04	7	66	2	PF01821
Domain	ANAPHYLATOXIN_2	C4A C4B	2.55e-04	7	66	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	2.55e-04	7	66	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	2.55e-04	7	66	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	3.40e-04	8	66	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	3.40e-04	8	66	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	3.40e-04	8	66	2	IPR019742
Domain	A2M_N	C4A C4B	5.43e-04	10	66	2	PF01835
Domain	A2M_N	C4A C4B	5.43e-04	10	66	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	5.43e-04	10	66	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	5.43e-04	10	66	2	PS00477
Domain	A2M	C4A C4B	5.43e-04	10	66	2	PF00207
Domain	A2M_N_2	C4A C4B	5.43e-04	10	66	2	IPR011625
Domain	A2M_comp	C4A C4B	5.43e-04	10	66	2	IPR011626
Domain	A2M_N_2	C4A C4B	5.43e-04	10	66	2	PF07703
Domain	A2M_recep	C4A C4B	5.43e-04	10	66	2	PF07677
Domain	A2M_comp	C4A C4B	5.43e-04	10	66	2	PF07678
Domain	Macroglobln_a2	C4A C4B	5.43e-04	10	66	2	IPR001599
Domain	C345C	C4A C4B	1.62e-03	17	66	2	SM00643
Domain	DUF1605	DHX36 DHX8	1.62e-03	17	66	2	IPR011709
Domain	OB_NTP_bind	DHX36 DHX8	1.62e-03	17	66	2	PF07717
Domain	HA2	DHX36 DHX8	1.81e-03	18	66	2	SM00847
Domain	HA2	DHX36 DHX8	1.81e-03	18	66	2	PF04408
Domain	Helicase-assoc_dom	DHX36 DHX8	1.81e-03	18	66	2	IPR007502
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	1.81e-03	18	66	2	IPR008930
Domain	NTR	C4A C4B	2.02e-03	19	66	2	PF01759
Domain	Fibrinogen_CS	FGG TNXB	2.02e-03	19	66	2	IPR020837
Domain	Netrin_module_non-TIMP	C4A C4B	2.02e-03	19	66	2	IPR018933
Domain	DEAD/DEAH_box_helicase_dom	DHX36 DDX55 DHX8	2.20e-03	73	66	3	IPR011545
Domain	DEAD	DHX36 DDX55 DHX8	2.20e-03	73	66	3	PF00270
Domain	P-loop_NTPase	DHX36 SMC1A GNL2 RNF213 DDX55 HS3ST1 PIF1 KIF11 DHX8	2.85e-03	848	66	9	IPR027417
Domain	NTR	C4A C4B	2.97e-03	23	66	2	PS50189
Domain	Netrin_domain	C4A C4B	2.97e-03	23	66	2	IPR001134
Domain	Fibrinogen_a/b/g_C_2	FGG TNXB	3.23e-03	24	66	2	IPR014715
Domain	-	FGG TNXB	3.23e-03	24	66	2	4.10.530.10
Domain	EGF_CA	MEGF8 C1R LTBP1	3.50e-03	86	66	3	PF07645
Domain	TIMP-like_OB-fold	C4A C4B	3.78e-03	26	66	2	IPR008993
Domain	TRYPSIN_SER	ACR C1R TMPRSS11A	3.98e-03	90	66	3	IPR033116
Domain	Fibrinogen_C	FGG TNXB	4.08e-03	27	66	2	PF00147
Domain	-	DHX36 SMC1A GNL2 RNF213 DDX55 HS3ST1 PIF1 DHX8	4.63e-03	746	66	8	3.40.50.300
Domain	FBG	FGG TNXB	4.70e-03	29	66	2	SM00186
Domain	EGF_Ca-bd_CS	MEGF8 C1R LTBP1	4.90e-03	97	66	3	IPR018097
Domain	-	FGG TNXB	5.02e-03	30	66	2	3.90.215.10
Domain	Fibrinogen_a/b/g_C_1	FGG TNXB	5.02e-03	30	66	2	IPR014716
Domain	EGF_CA	MEGF8 C1R LTBP1	5.19e-03	99	66	3	PS01187
Domain	ASX_HYDROXYL	MEGF8 C1R LTBP1	5.34e-03	100	66	3	PS00010
Domain	FIBRINOGEN_C_1	FGG TNXB	5.70e-03	32	66	2	PS00514
Domain	Fibrinogen_a/b/g_C_dom	FGG TNXB	5.70e-03	32	66	2	IPR002181
Domain	FIBRINOGEN_C_2	FGG TNXB	5.70e-03	32	66	2	PS51406
Domain	TRYPSIN_HIS	ACR C1R TMPRSS11A	5.80e-03	103	66	3	IPR018114
Domain	TRYPSIN_SER	ACR C1R TMPRSS11A	6.27e-03	106	66	3	PS00135
Domain	EGF-type_Asp/Asn_hydroxyl_site	MEGF8 C1R LTBP1	6.27e-03	106	66	3	IPR000152
Domain	Helicase_C	DHX36 DDX55 DHX8	6.44e-03	107	66	3	PF00271
Domain	TRYPSIN_HIS	ACR C1R TMPRSS11A	6.44e-03	107	66	3	PS00134
Domain	HELICc	DHX36 DDX55 DHX8	6.44e-03	107	66	3	SM00490
Domain	Helicase_C	DHX36 DDX55 DHX8	6.61e-03	108	66	3	IPR001650
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C1R C4A C4B	2.05e-06	8	48	3	M47872
Pathway	BIOCARTA_CLASSIC_PATHWAY	C1R C4A C4B	7.98e-06	12	48	3	MM1368
Pathway	BIOCARTA_CLASSIC_PATHWAY	C1R C4A C4B	1.64e-05	15	48	3	M7146
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C1R C4A C4B	2.44e-05	17	48	3	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C1R C4A C4B	2.44e-05	17	48	3	MM1369
Pathway	BIOCARTA_COMP_PATHWAY	C1R C4A C4B	4.06e-05	20	48	3	M917
Pathway	WP_COMPLEMENT_ACTIVATION	C1R C4A C4B	5.45e-05	22	48	3	M39502
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	C1R C4A C4B FGG	8.69e-05	69	48	4	M16894
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL6A3 LOX LOXL1 LTBP1 FGG TNXB	2.28e-04	258	48	6	MM14572
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	2.36e-04	7	48	2	MM14685
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LOX LOXL1 LTBP1	3.11e-04	39	48	3	MM14601
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	3.14e-04	8	48	2	M27031
Pathway	WP_OXIDATIVE_DAMAGE_RESPONSE	C1R C4A C4B	3.87e-04	42	48	3	MM15945
Pathway	KEGG_MEDICUS_REFERENCE_COHESIN_LOADING	SMC1A STAG2	4.03e-04	9	48	2	M47868
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LOX LOXL1 LTBP1	4.45e-04	44	48	3	M26969
Pathway	WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY	PARD6G C1R C4A C4B	4.56e-04	106	48	4	M42535
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	SMC1A STAG2	5.02e-04	10	48	2	M27178
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	SMC1A STAG2	5.02e-04	10	48	2	MM14892
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL6A3 LOX LOXL1 LTBP1 FGG TNXB	5.11e-04	300	48	6	M610
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	6.12e-04	11	48	2	M47874
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	SMC1A STAG2	6.12e-04	11	48	2	M27177
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	SMC1A STAG2	6.12e-04	11	48	2	MM14891
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	6.12e-04	11	48	2	MM1430
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL6A3 LOX LOXL1	6.49e-04	50	48	3	MM14796
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	C4A C4B LTBP1 FGG	7.28e-04	120	48	4	MM14982
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	GUSB CSPG4 HS3ST1	8.14e-04	54	48	3	MM14633
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	C1R C4A C4B	8.14e-04	54	48	3	MM14655
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	SMC1A STAG2	8.65e-04	13	48	2	MM15363
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	SMC1A STAG2	8.65e-04	13	48	2	M27661
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	8.65e-04	13	48	2	M4732
Pathway	REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM	GUSB CSPG4 HS3ST1	9.53e-04	57	48	3	M692
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL6A3 LOX LOXL1	1.16e-03	61	48	3	M27103
Pathway	BIOCARTA_SPRY_PATHWAY	RAF1 PTPRB	1.32e-03	16	48	2	MM1500
Pathway	PID_INTEGRIN1_PATHWAY	COL6A3 CSPG4 FGG	1.46e-03	66	48	3	M18
Pathway	BIOCARTA_SPRY_PATHWAY	RAF1 PTPRB	1.49e-03	17	48	2	M1389
Pathway	WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING	LOX LOXL1	1.49e-03	17	48	2	M39686
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	LOX LOXL1	1.68e-03	18	48	2	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	LOX LOXL1	1.68e-03	18	48	2	MM14882
Pathway	BIOCARTA_ECM_PATHWAY	RAF1 GSN	1.87e-03	19	48	2	M6355
Pathway	REACTOME_COLLAGEN_FORMATION	COL6A3 LOX LOXL1	2.19e-03	76	48	3	MM14573
Pathway	BIOCARTA_ECM_PATHWAY	RAF1 GSN	2.29e-03	21	48	2	MM1390
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	C1R C4A C4B	2.53e-03	80	48	3	M6121
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	COL6A3 MEGF8 GUSB CSPG4 C1R C4A FGG TNXB	3.57e-08	257	67	8	16335952
Pubmed	Androgen-dependent hereditary mouse keratoconus: linkage to an MHC region.	C4A C4B TNXB	1.36e-07	6	67	3	11773012
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL6A3 LOXL1 CSPG4 LTBP1 FGG TNXB	2.51e-07	135	67	6	28675934
Pubmed	Molecular genetics of the human MHC complement gene cluster.	C4A C4B TNXB	3.80e-07	8	67	3	10072631
Pubmed	Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.	LOX LOXL1 LTBP1	3.80e-07	8	67	3	27339457
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL6A3 LOXL1 CSPG4 LTBP1 TNXB GSN	3.99e-07	146	67	6	27068509
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	RAF1 DHX36 NEPRO WDCP GNL2 TNKS1BP1 IDE DHX8	5.08e-07	364	67	8	24778252
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL6A3 LOXL1 LTBP1 FGG TNXB	7.03e-07	86	67	5	28327460
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	COL6A3 MEGF8 GUSB CSPG4 C1R C4A C4B FGG FLOT1 TNXB GSN CA4	8.53e-07	1070	67	12	23533145
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL6A3 LOX LOXL1 CSPG4 LTBP1 FGG	8.77e-07	167	67	6	22159717
Pubmed	Organizations and gene duplications of the human and mouse MHC complement gene clusters.	C4A C4B TNXB	1.12e-06	11	67	3	10686478
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DHX36 MEGF8 GUSB LOX LOXL1 CSPG4 RNF213 C4A TNKS1BP1 LTBP1 DDX55 TOR1AIP1	2.83e-06	1201	67	12	35696571
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	3.66e-06	2	67	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	3.66e-06	2	67	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	3.66e-06	2	67	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	3.66e-06	2	67	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	3.66e-06	2	67	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	3.66e-06	2	67	2	3696167
Pubmed	Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues.	LOX LOXL1	3.66e-06	2	67	2	15609098
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	3.66e-06	2	67	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	3.66e-06	2	67	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	3.66e-06	2	67	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	3.66e-06	2	67	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	3.66e-06	2	67	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	3.66e-06	2	67	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	3.66e-06	2	67	2	12207352
Pubmed	Neuron/Glial Antigen 2-Type VI Collagen Interactions During Murine Temporomandibular Joint Osteoarthritis.	COL6A3 CSPG4	3.66e-06	2	67	2	30635602
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	3.66e-06	2	67	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	3.66e-06	2	67	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	3.66e-06	2	67	2	27758680
Pubmed	Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer.	LOX LOXL1	3.66e-06	2	67	2	26804196
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	3.66e-06	2	67	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	3.66e-06	2	67	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	3.66e-06	2	67	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	3.66e-06	2	67	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	3.66e-06	2	67	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	3.66e-06	2	67	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	3.66e-06	2	67	2	23918728
Pubmed	Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.	LOX LOXL1	3.66e-06	2	67	2	38466882
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	3.66e-06	2	67	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	3.66e-06	2	67	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	3.66e-06	2	67	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	3.66e-06	2	67	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	3.66e-06	2	67	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	3.66e-06	2	67	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	3.66e-06	2	67	2	2997024
Pubmed	Cohesin complex-associated holoprosencephaly.	SMC1A STAG2	3.66e-06	2	67	2	31334757
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	3.66e-06	2	67	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	3.66e-06	2	67	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	3.66e-06	2	67	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	3.66e-06	2	67	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	3.66e-06	2	67	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	3.66e-06	2	67	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	3.66e-06	2	67	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	3.66e-06	2	67	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	3.66e-06	2	67	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	3.66e-06	2	67	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	3.66e-06	2	67	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	3.66e-06	2	67	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	3.66e-06	2	67	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	3.66e-06	2	67	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	3.66e-06	2	67	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	3.66e-06	2	67	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	3.66e-06	2	67	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	3.66e-06	2	67	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	3.66e-06	2	67	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	3.66e-06	2	67	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	3.66e-06	2	67	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	3.66e-06	2	67	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	3.66e-06	2	67	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	3.66e-06	2	67	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	3.66e-06	2	67	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	3.66e-06	2	67	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	3.66e-06	2	67	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	3.66e-06	2	67	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	3.66e-06	2	67	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	3.66e-06	2	67	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	3.66e-06	2	67	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	3.66e-06	2	67	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	3.66e-06	2	67	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	3.66e-06	2	67	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	3.66e-06	2	67	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	3.66e-06	2	67	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	3.66e-06	2	67	2	7365238
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	3.66e-06	2	67	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	3.66e-06	2	67	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	3.66e-06	2	67	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	3.66e-06	2	67	2	17971360
Pubmed	A new gene with sequence and structural similarity to the gene encoding human lysyl oxidase.	LOX LOXL1	3.66e-06	2	67	2	7706256
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	3.66e-06	2	67	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	3.66e-06	2	67	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	3.66e-06	2	67	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	3.66e-06	2	67	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	3.66e-06	2	67	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	3.66e-06	2	67	2	6881182
Pubmed	Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell.	LOX LOXL1	3.66e-06	2	67	2	12577300
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	3.66e-06	2	67	2	3944109
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	3.66e-06	2	67	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	3.66e-06	2	67	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	3.66e-06	2	67	2	6978711
Interaction	IL5RA interactions	MEGF8 GUSB CSPG4 OS9 C4A HS3ST1	3.53e-06	124	67	6	int:IL5RA
GeneFamily	Complement system\|Sushi domain containing	C1R C4A C4B	1.04e-04	36	46	3	492
GeneFamily	Cohesin complex	SMC1A STAG2	1.76e-04	8	46	2	1060
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.25e-04	9	46	2	1234
GeneFamily	DEAH-box helicases	DHX36 DHX8	7.43e-04	16	46	2	500
GeneFamily	Fibrinogen C domain containing	FGG TNXB	1.83e-03	25	46	2	554
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	3.99e-03	37	46	2	454
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL6A3 LOX LOXL1 LTBP1	1.81e-06	35	66	4	M11788
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL6A3 LOX LOXL1 LTBP1	2.03e-06	36	66	4	MM1212
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	COL6A3 ANK2 LOX LOXL1 C1R NFKBIZ GSN	9.61e-06	296	66	7	M41675
Coexpression	RODWELL_AGING_KIDNEY_NO_BLOOD_UP	COL6A3 LOXL1 RNF213 C1R NFKBIZ C4A	2.16e-05	224	66	6	M9893
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	COL6A3 GUSB OR51M1 LOX LOXL1 DENND4B FES SYP LTBP1 PIF1 GSN FN3K	5.57e-05	1242	66	12	M1920
Coexpression	URS_ADIPOCYTE_DIFFERENTIATION_DN	COL6A3 LOX LOXL1	6.52e-05	31	66	3	M18395
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	COL6A3 LOX LOXL1 C1R TNXB GSN	5.66e-07	97	66	6	GSM777046_100
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	COL6A3 LOX LOXL1 C1R C4A C4B LTBP1 TNXB GSN	1.33e-05	466	66	9	GSM777050_500
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	COL6A3 LOX LOXL1 C1R C4B LTBP1 TNXB GSN	6.10e-05	437	66	8	GSM777046_500
CoexpressionAtlas	Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2	NRARP COL6A3 LOX LOXL1 C1R C4B TNXB GSN	7.84e-05	453	66	8	GSM777067_500
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	COL6A3 LOX LOXL1 C1R C4A C4B TNXB GSN	8.08e-05	455	66	8	GSM777055_500
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000	COL6A3 LOX LOXL1 NFKBIZ C4B TNXB GSN	1.46e-04	369	66	7	gudmap_kidney_adult_RenalCapsule_k2_1000
ToppCell	(5)_Fibroblast-A_(Fibroblast_progenitors)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB GSN	6.63e-10	199	67	8	b783917fe0a9725a680aa430a42f02ce294900ef
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB GSN	6.90e-10	200	67	8	28e5354008adf97b17333f17f8cbef930db6729a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB GSN	6.90e-10	200	67	8	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB GSN	6.90e-10	200	67	8	14f3fe19b6647b32a5e28d717235741997d8522c
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB GSN	6.90e-10	200	67	8	56536236a7012efdb28f85b40e464f3da3e87ce8
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB GSN	1.16e-08	183	67	7	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOX LOXL1 C4B LTBP1 TNXB GSN	1.56e-08	191	67	7	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOX LOXL1 C4B LTBP1 TNXB GSN	1.62e-08	192	67	7	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOX LOXL1 C4B LTBP1 TNXB GSN	1.62e-08	192	67	7	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	1.62e-08	192	67	7	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B LTBP1 TNXB GSN	1.68e-08	193	67	7	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B LTBP1 TNXB GSN	1.68e-08	193	67	7	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	1.80e-08	195	67	7	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	1.93e-08	197	67	7	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	1.93e-08	197	67	7	c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell	368C-Fibroblasts-Fibroblast-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.07e-08	199	67	7	5a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.07e-08	199	67	7	9672230aa0bc6a7289050c955f5154ca183a5159
ToppCell	368C-Fibroblasts-Fibroblast-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.07e-08	199	67	7	66545eb7f65e450b742628fd431956e13330a0d3
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.07e-08	199	67	7	e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 GSN	2.07e-08	199	67	7	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 GSN	2.07e-08	199	67	7	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.07e-08	199	67	7	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	(5)_Fibroblast-D\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.07e-08	199	67	7	3f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	Biopsy_Other_PF-Mesenchymal-Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	9996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	17ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCell	normal_Lung-Fibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	803cf7f1382d07220249029cd220233232027689
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	bfa73bc5f8a6c7de8353ca049a921ef19f7f4437
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	2e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	665df8391d2ebcfc6536318612f4992852b5e2b8
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	Parenchyma_Control_(B.)-Stromal-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	0a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCell	356C-Fibroblasts\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	9c95329f0b26ff378de803030d4c28517b3adc85
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	3fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	ef30f9b68bfdb8d947ed399603e4dd0d5ff0144d
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	6b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	b28bfe6eb96b4db9cb27f0fc8fc39259c125f05e
ToppCell	Lung_Parenchyma-Control-Mesenchymal\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	1e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	5c6520dc4c4693827f6680651785680b5883afb8
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB GSN	2.14e-08	200	67	7	ee3d06865a6300e1279edf6664320b71647f5efb
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ANK2 LOX LOXL1 C1R LTBP1 TNXB	2.14e-08	200	67	7	87953ea65ff2a01485e13dd49d993ae6ae679cbf
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 LOX LOXL1 LTBP1 TNXB GSN	1.84e-07	165	67	6	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 ANK2 LOX LOXL1 LTBP1 GSN	1.98e-07	167	67	6	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOX C1R LTBP1 TNXB	2.35e-07	172	67	6	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB	2.69e-07	176	67	6	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB	2.69e-07	176	67	6	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 C1R LTBP1 TNXB GSN	3.28e-07	182	67	6	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	3.39e-07	183	67	6	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	3.39e-07	183	67	6	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	COL6A3 LOX LOXL1 C1R LTBP1 TNXB	3.61e-07	185	67	6	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 C1R LTBP1 TNXB GSN	4.09e-07	189	67	6	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOX NFKBIZ C4B LTBP1 IDE FLOT1	4.09e-07	189	67	6	562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOX NFKBIZ C4B LTBP1 IDE FLOT1	4.09e-07	189	67	6	270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOX LOXL1 C4B TNXB GSN	4.09e-07	189	67	6	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOX LOXL1 C4B LTBP1 TNXB GSN	4.35e-07	191	67	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LOX LOXL1 C4B LTBP1 TNXB GSN	4.49e-07	192	67	6	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.49e-07	192	67	6	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 C1R LTBP1 TNXB GSN	4.49e-07	192	67	6	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.49e-07	192	67	6	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL6A3 ANK2 LOX C1R LTBP1 TNXB	4.49e-07	192	67	6	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.49e-07	192	67	6	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.49e-07	192	67	6	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.49e-07	192	67	6	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 C1R LTBP1 TNXB GSN	4.49e-07	192	67	6	2143e1fad2e88b90d668e12af37b2092d379090f
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LOX LOXL1 C4B TNXB GSN	4.63e-07	193	67	6	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.63e-07	193	67	6	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 ANK2 LOX C1R LTBP1 TNXB	4.63e-07	193	67	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.63e-07	193	67	6	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.63e-07	193	67	6	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LOX LOXL1 C4B TNXB GSN	4.63e-07	193	67	6	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOX LOXL1 C4B TNXB GSN	4.63e-07	193	67	6	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.77e-07	194	67	6	c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 C1R LTBP1 TNXB GSN	4.77e-07	194	67	6	35b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	COL6A3 LOXL1 C1R RAB11FIP1 GSN CA4	4.77e-07	194	67	6	8ac0b63c7a89e5ff78bbdd8dd1960aa2422a85f7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Mesenchymal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	COL6A3 LOXL1 C1R RAB11FIP1 GSN CA4	4.77e-07	194	67	6	4bafe26573cb2ff966f4a688c5769da598eea415
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.77e-07	194	67	6	889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	COL6A3 ANK2 LOX LOXL1 C1R LTBP1	4.92e-07	195	67	6	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.92e-07	195	67	6	0feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.92e-07	195	67	6	2a6f67875cef140b0e6b8401436719675c6b3665
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 ANK2 LOXL1 C1R LTBP1 TNXB	4.92e-07	195	67	6	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRARP LOX LOXL1 CSPG4 C4B LTBP1	4.92e-07	195	67	6	43d372373367b71243c6ea958aedccde4478618f
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.92e-07	195	67	6	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	facs-Trachea-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	4.92e-07	195	67	6	0d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	5.06e-07	196	67	6	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 LOX C1R LTBP1 TNXB GSN	5.06e-07	196	67	6	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 LOX C1R LTBP1 TNXB GSN	5.06e-07	196	67	6	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	5.06e-07	196	67	6	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	IPF-Stromal-Fibroblast\|IPF / Disease state, Lineage and Cell class	COL6A3 ANK2 LOX LOXL1 C1R LTBP1	5.06e-07	196	67	6	f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	5.06e-07	196	67	6	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	PND28-Mesenchymal\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LOX LOXL1 CSPG4 C4B GSN	5.06e-07	196	67	6	119265efd2219f328d8152dbee52af8327aec89c
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LOXL1 C4B LTBP1 TNXB GSN	5.06e-07	196	67	6	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 LOX C1R LTBP1 TNXB GSN	5.06e-07	196	67	6	85e5046f774537684e1443c0fc147d562b7068d0
Computational	Complement.	C1R C4A C4B	1.07e-04	23	44	3	MODULE_130
Computational	Metal / Ca ion binding.	LOXL1 C1R LTBP1 GSN CA4	1.98e-04	133	44	5	MODULE_324
Computational	ECM and collagens.	COL6A3 LOX LOXL1 DENND4B C1R LTBP1	2.86e-04	225	44	6	MODULE_47
Drug	pregnanetriol	GUSB ACR C4A TNXB	3.76e-06	36	67	4	CID000101967
Disease	Complement deficiency disease	C1R C4A C4B	4.61e-05	33	62	3	C0272242
Disease	Paratuberculosis	C1R GSN	6.48e-05	6	62	2	C0030524
Disease	intraocular pressure measurement	COL6A3 LOX CSPG4 GNL2 LTBP1 HS3ST1 TNXB	9.45e-05	509	62	7	EFO_0004695
Disease	pulse pressure measurement	COL6A3 ANK2 MEGF8 LOXL1 FES RNF213 LTBP1 ST18 PIF1 GSN DHX8	1.37e-04	1392	62	11	EFO_0005763
Disease	Ehlers-Danlos syndrome (is_implicated_in)	LOX TNXB	1.55e-04	9	62	2	DOID:13359 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	C1R C4A C4B	4.56e-04	71	62	3	C0024141
Disease	sex interaction measurement, ulcerative colitis	OS9 TNXB	5.79e-04	17	62	2	EFO_0000729, EFO_0008343
Disease	Myeloid Leukemia	SMC1A STAG2	6.50e-04	18	62	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC1A STAG2	6.50e-04	18	62	2	C0023466
Disease	pulmonary embolism	BANP FGG	1.26e-03	25	62	2	EFO_0003827
Disease	complement C4b measurement	C1R TNXB	1.26e-03	25	62	2	EFO_0008092

Protein segments in the cluster

Peptide	Gene	Start	Entry
SNAVPGRRQNTIVVK	BANP	151	Q8N9N5
GRRQNTIVVKVPGQE	BANP	156	Q8N9N5
RTLKAEIQVGLQPGQ	ARMT1	401	Q9H993
VQAPRKGNLQLQGTR	CSPG4	826	Q6UVK1
VPRGQVVKGSVFLRN	C4B	46	P0C0L5
LRFRQNPQGGVRIVG	ACR	31	P10323
NPVEQRQRIIGGQKA	C1R	456	P00736
FLPNKQRTVVNVRNG	RAF1	61	P04049
PVGKVQRIVIFKRNG	HNRNPLL	191	Q8WVV9
ENQTIKRGQRLPVTG	ANK2	2046	Q01484
GSLKNQINVVGRTVP	PTPRB	981	P23467
LTRVRQNFGKINVVP	GNL2	526	Q13823
QQRGPFQGVRVKNSV	NFKBIZ	106	Q9BYH8
QRTRGQTQDLKVGQP	MAGEB4	16	O15481
APQTQRIFQEAVRKG	NRARP	11	Q7Z6K4
GKNIQVVVRCRPFNL	KIF11	16	P52732
FLGSVQIRVPRQGKQ	LOXHD1	766	Q8IVV2
VRVLLRFPQRVKNQG	LOXL1	416	Q08397
KQQGGNIIVATPGRL	DDX55	131	Q8NHQ9
GGRVFVLPCIQQIQR	FLOT1	26	O75955
FTKQGRQVVRSKVPQ	LTBP1	131	Q14766
QQVVRAGLIVIFRGP	OR51M1	151	Q9H341
KGQRQVLREAPGFVT	MEGF8	31	Q7Z7M0
EGIGRTFNQVVKPRV	GPKOW	181	Q92917
GQPVQGKTQIRVCRE	OVOS2	236	Q6IE36
KNNRFGRNPVVLLGI	MFSD11	301	O43934
TVKPANQRNNVVRGG	PARD6G	246	Q9BYG4
KIIPFNRLTIGEGQQ	FGG	411	P02679
IIAKIQQRGQGAPAR	CFAP298	216	P57076
RPLQQLGQRTVIKSG	CA4	271	P22748
VNQTQVFKRTPPGVR	DHX36	531	Q9H2U1
VLGNKKGIFTRQRQP	GUSB	601	P08236
KLPIGTQQIRVGVVQ	COL6A3	271	P12111
LNIGPSKVRVGVVQF	COL6A3	1466	P12111
VLLRFPQRVKNQGTS	LOX	261	P28300
KLRNVVLGAAQFRQP	DENND4B	876	O75064
PNEVVVQRLFQVKGR	GSN	181	P06396
NGIQGLRFIIQSEKP	IDE	841	P14735
EGSQPRIFRIKLGNQ	FDXACB1	201	Q9BRP7
GRPKAVLQAVGQLVQ	HPS6	631	Q86YV9
SVPGRVLKNANIVQG	PIWIL3	466	Q7Z3Z3
VPRGQVVKGSVFLRN	C4A	46	P0C0L4
VTPISQAQAKQRAGR	DHX8	876	Q14562
NQQTREFVEKGGRLP	FES	766	P07332
AQQLPQTIIIGVRKG	HS3ST1	51	O14792
AVARAVRQQNKPFGG	PIF1	321	Q9H611
VRQQNKPFGGIQLII	PIF1	326	Q9H611
NQLVAGGQFRVVKEP	SYP	11	P08247
QVTVLQARGLRAKGP	RAB11FIP1	21	Q6WKZ4
PINVVKTRIQSQIGG	SLC25A51	231	Q9H1U9
FRRLVNSQGQLRVPV	HDHD5	71	Q9BXW7
RIPKAGNRSAVTVQN	NEPRO	16	Q6NW34
GPVFVKVNRRTQARQ	FN3K	36	Q9H479
KPQGSLVRVIQRAGL	ST6GALNAC6	191	Q969X2
PINVVKTRLQSQIGG	SLC25A52	231	Q3SY17
VRVRVTKLRLGGPNQ	OS9	541	Q13438
VFGKRPLIQTVQGRK	ST18	511	O60284
GKSPAQILIRFQIQR	AKR1E2	246	Q96JD6
IQRQIVSRFLQGKPR	RNF213	4956	Q63HN8
LQQGIFPIKNGRKVS	ZNF804B	146	A4D1E1
RQVTGQPQNASFVKR	TOR1AIP1	321	Q5JTV8
RGRQGPNANLVKTLV	STAG2	451	Q8N3U4
QDRVVGKPAQLGTQR	TNKS1BP1	821	Q9C0C2
QARTQKLQGLIPGAR	TNXB	3806	P22105
KGRQIIGPFQRFTAI	SMC1A	16	Q14683
IFQPNGKIVTRFGSR	TRIM2	601	Q9C040
GSLKRTQFPGREQQV	TMUB1	126	Q9BVT8
SQNGRPGRTLIKEIQ	WDCP	486	Q9H6R7
GKRVVPLNVNRIASG	TMPRSS11A	176	Q6ZMR5
GVRALKVIQQGNRPG	VPS13D	3361	Q5THJ4