Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	growth factor activity	BMP8B FGF3 FGF13 BMP8A GDF10	1.58e-04	173	59	5	GO:0008083
GeneOntologyMolecularFunction	chromatin binding	MTA2 HMGA2 H1-7 ASH1L MBD6 EZH2 SFMBT2 CBX2 BAHCC1	2.97e-04	739	59	9	GO:0003682
GeneOntologyCellularComponent	heterochromatin	NCAPD3 HMGA2 NOP53 EZH2 CBX2	8.17e-06	101	57	5	GO:0000792
GeneOntologyCellularComponent	chromatin	FOXE1 MTA2 NCAPD3 AHRR HMGA2 EGR4 NOP53 H1-7 SRCAP EZH2 FOXF2 FOXD1 CBX2	1.38e-04	1480	57	13	GO:0000785
Domain	AT_hook	HMGA2 ASH1L SRCAP CBX2	1.30e-06	27	57	4	SM00384
Domain	AT_hook_DNA-bd_motif	HMGA2 ASH1L SRCAP CBX2	1.30e-06	27	57	4	IPR017956
Domain	BAH	MTA2 ASH1L BAHCC1	4.37e-06	11	57	3	SM00439
Domain	BAH	MTA2 ASH1L BAHCC1	4.37e-06	11	57	3	PF01426
Domain	BAH	MTA2 ASH1L BAHCC1	4.37e-06	11	57	3	PS51038
Domain	BAH_dom	MTA2 ASH1L BAHCC1	4.37e-06	11	57	3	IPR001025
Domain	TGFb_propeptide	BMP8B BMP8A GDF10	8.36e-05	28	57	3	PF00688
Domain	TGF-b_N	BMP8B BMP8A GDF10	8.36e-05	28	57	3	IPR001111
Domain	TGF-beta-rel	BMP8B BMP8A GDF10	1.26e-04	32	57	3	IPR015615
Domain	TGFb_CS	BMP8B BMP8A GDF10	1.26e-04	32	57	3	IPR017948
Domain	TGFB	BMP8B BMP8A GDF10	1.95e-04	37	57	3	SM00204
Domain	TGF-b_C	BMP8B BMP8A GDF10	1.95e-04	37	57	3	IPR001839
Domain	TGF_BETA_2	BMP8B BMP8A GDF10	1.95e-04	37	57	3	PS51362
Domain	TGF_beta	BMP8B BMP8A GDF10	1.95e-04	37	57	3	PF00019
Domain	TGF_BETA_1	BMP8B BMP8A GDF10	1.95e-04	37	57	3	PS00250
Domain	TF_fork_head_CS_2	FOXE1 FOXF2 FOXD1	3.73e-04	46	57	3	IPR030456
Domain	TF_fork_head_CS_1	FOXE1 FOXF2 FOXD1	3.97e-04	47	57	3	IPR018122
Domain	FH	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	SM00339
Domain	FORK_HEAD_1	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	PS00657
Domain	FORK_HEAD_2	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	PS00658
Domain	Fork_head_dom	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	IPR001766
Domain	FORK_HEAD_3	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	PS50039
Domain	Forkhead	FOXE1 FOXF2 FOXD1	4.49e-04	49	57	3	PF00250
Domain	Inhibin_asu	BMP8B BMP8A	6.99e-04	13	57	2	IPR002405
Domain	EGF_extracell	HHIP SCARF2 ADAM11	8.15e-04	60	57	3	IPR013111
Domain	EGF_2	HHIP SCARF2 ADAM11	8.15e-04	60	57	3	PF07974
Domain	-	BMP8B BMP8A GDF10	1.12e-03	67	57	3	2.10.90.10
Domain	Cystine-knot_cytokine	BMP8B BMP8A GDF10	1.12e-03	67	57	3	IPR029034
Domain	FGF	FGF3 FGF13	2.03e-03	22	57	2	SM00442
Domain	FGF	FGF3 FGF13	2.03e-03	22	57	2	PF00167
Domain	HBGF_FGF	FGF3 FGF13	2.03e-03	22	57	2	PS00247
Domain	Fibroblast_GF_fam	FGF3 FGF13	2.03e-03	22	57	2	IPR002209
Domain	IL-1_fam/FGF_fam	FGF3 FGF13	2.22e-03	23	57	2	IPR028142
Domain	HMGI/Y_DNA-bd_CS	HMGA2 CBX2	4.02e-03	31	57	2	IPR000637
Domain	Cytokine_IL1-like	FGF3 FGF13	5.39e-03	36	57	2	IPR008996
Domain	EGF_3	HHIP SCARF2 ADAM11 LTBP4	5.73e-03	235	57	4	PS50026
Domain	EGF	HHIP SCARF2 ADAM11 LTBP4	5.73e-03	235	57	4	SM00181
Domain	SET	ASH1L EZH2	6.95e-03	41	57	2	PF00856
Domain	EGF-like_dom	HHIP SCARF2 ADAM11 LTBP4	7.01e-03	249	57	4	IPR000742
Domain	EGF_1	HHIP SCARF2 ADAM11 LTBP4	7.61e-03	255	57	4	PS00022
Domain	EGF-like_CS	HHIP SCARF2 ADAM11 LTBP4	8.24e-03	261	57	4	IPR013032
Domain	EGF_2	HHIP SCARF2 ADAM11 LTBP4	8.69e-03	265	57	4	PS01186
Domain	SET	ASH1L EZH2	8.69e-03	46	57	2	SM00317
Domain	SET_dom	ASH1L EZH2	1.02e-02	50	57	2	IPR001214
Domain	SANT	MTA2 EZH2	1.02e-02	50	57	2	SM00717
Domain	SET	ASH1L EZH2	1.02e-02	50	57	2	PS50280
Domain	SANT/Myb	MTA2 EZH2	1.10e-02	52	57	2	IPR001005
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MTA2 CCDC71L BMP8B SH3PXD2B SRCAP MBD6 LTBP4 FBXO46 SOWAHB CABLES1 CBX2 BAHCC1	2.82e-07	1105	59	12	35748872
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	MTA2 ASH1L SRCAP MBD6 EZH2 CBX2	2.84e-07	157	59	6	30186101
Pubmed	Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.	FOXE1 FOXF2 FOXD1	7.58e-07	11	59	3	28506991
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	MTA2 CCDC71L NOP53 ZNF689 MBD6 EZH2 FBXO46 CBX2	1.87e-06	495	59	8	27705803
Pubmed	Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.	BMP8B BMP8A	2.83e-06	2	59	2	31940275
Pubmed	HMGA2 Synergizes with EZH2 to Mediate Epithelial Cell Inflammation and Apoptosis in Septic Lung Dysfunction.	HMGA2 EZH2	2.83e-06	2	59	2	36564076
Pubmed	TWEAK and TNF regulation of sclerostin: a novel pathway for the regulation of bone remodelling.	SOST TNFSF12	2.83e-06	2	59	2	21153337
Pubmed	Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.	BMP8B BMP8A	2.83e-06	2	59	2	9463357
Pubmed	The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.	BMP8B BMP8A	2.83e-06	2	59	2	8682296
Pubmed	Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells.	SH3PXD2B EZH2	2.83e-06	2	59	2	38672463
Pubmed	The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.	BMP8B BMP8A	2.83e-06	2	59	2	21277400
Pubmed	Sclerostin and TNF-related weak inducer of apoptosis: can they be important in the patients with glomerulonephritis?	SOST TNFSF12	2.83e-06	2	59	2	37466605
Pubmed	Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.	BMP8B FGF3 FGF13 BMP8A	4.98e-06	66	59	4	12666204
Pubmed	UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.	MRPL15 ZNF689 EZH2 SFMBT2 RPL13	6.79e-06	155	59	5	34921745
Pubmed	Specialized distribution of the histone methyltransferase Ezh2 in the nuclear apical region of round spermatids and its interaction with the histone variant H1t2.	H1-7 EZH2	8.48e-06	3	59	2	22323620
Pubmed	Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.	BMP8B BMP8A	8.48e-06	3	59	2	9076678
Pubmed	Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).	BMP8B BMP8A	8.48e-06	3	59	2	12925636
Pubmed	Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.	EZH2 CBX2	8.48e-06	3	59	2	26431491
Pubmed	Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.	EZH2 CBX2	8.48e-06	3	59	2	25801166
Pubmed	Polymorphisms in FGF3, FGF10, and FGF13 May Contribute to the Presence of Temporomandibular Disorders in Patients Who Required Orthognathic Surgery.	FGF3 FGF13	8.48e-06	3	59	2	31574782
Pubmed	Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms.	HMGA2 EZH2	8.48e-06	3	59	2	29296743
Pubmed	Requirement of Bmp8b for the generation of primordial germ cells in the mouse.	BMP8B BMP8A	8.48e-06	3	59	2	10894154
Pubmed	BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.	BMP8B BMP8A	8.48e-06	3	59	2	22579288
Pubmed	Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.	BMP8B BMP8A	8.48e-06	3	59	2	11784057
Pubmed	Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.	BMP8B BMP8A	8.48e-06	3	59	2	25451979
Pubmed	Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.	BMP8B BMP8A	1.69e-05	4	59	2	9434160
Pubmed	Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.	BMP8B BMP8A	1.69e-05	4	59	2	8843393
Pubmed	ATRX proximal protein associations boast roles beyond histone deposition.	MTA2 CCDC71L UTP14A EZH2	1.79e-05	91	59	4	34780483
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	BMP8B SCARF2 GUCY2D TULP1 FOXF2 RPL13	2.02e-05	329	59	6	17474147
Pubmed	Corepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27.	EZH2 CBX2	2.82e-05	5	59	2	22009739
Pubmed	NCAPD3 promotes prostate cancer progression by up-regulating EZH2 and MALAT1 through STAT3 and E2F1.	NCAPD3 EZH2	2.82e-05	5	59	2	35085770
Pubmed	Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.	HHIP HMGA2 CABLES1	3.46e-05	37	59	3	19266077
Pubmed	Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.	HHIP BMP8B SOST BMP8A	3.51e-05	108	59	4	31202927
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	PDE3B SCARF2 GPATCH1 RPL13 SLC4A2 JPH3	4.20e-05	375	59	6	32788342
Pubmed	Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.	BMP8B BMP8A	4.23e-05	6	59	2	9878243
Pubmed	Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.	BMP8B BMP8A	4.23e-05	6	59	2	7605753
Pubmed	Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.	MBTPS1 UTP14A	4.23e-05	6	59	2	15938716
Pubmed	The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.	BMP8B BMP8A	5.91e-05	7	59	2	9070944
Pubmed	Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.	BMP8B BMP8A	5.91e-05	7	59	2	12107726
Pubmed	Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.	BMP8B BMP8A	1.01e-04	9	59	2	15028287
Pubmed	Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.	BMP8B BMP8A	1.01e-04	9	59	2	1460021
Pubmed	TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.	BMP8B BMP8A GDF10	1.14e-04	55	59	3	15342483
Pubmed	A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.	EZH2 CBX2	1.26e-04	10	59	2	20808772
Pubmed	An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin.	HHIP FOXD1	1.54e-04	11	59	2	26256211
Pubmed	Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.	BMP8B BMP8A	1.54e-04	11	59	2	10721728
Pubmed	Genome-wide association study of height and body mass index in Australian twin families.	HHIP HMGA2	1.85e-04	12	59	2	20397748
Pubmed	The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.	MTA2 HMGA2 EZH2	1.97e-04	66	59	3	32051553
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXF2 FOXD1	2.18e-04	13	59	2	7957066
Pubmed	Bmp7 regulates germ cell proliferation in mouse fetal gonads.	BMP8B BMP8A	2.18e-04	13	59	2	18391523
Pubmed	Deletion of Lrp4 increases the incidence of microphthalmia.	BMP8B BMP8A GDF10	2.24e-04	69	59	3	30352686
Pubmed	New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.	BMP8B BMP8A	2.54e-04	14	59	2	11526197
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	ASH1L SRCAP	2.54e-04	14	59	2	28263302
Pubmed	Cilia-dependent GLI processing in neural crest cells is required for tongue development.	FOXF2 FOXD1	2.54e-04	14	59	2	28286175
Pubmed	DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.	MTA2 EZH2	2.93e-04	15	59	2	35695185
Pubmed	Global comparative transcriptome analysis of cartilage formation in vivo.	BMP8B BMP8A	3.34e-04	16	59	2	19272164
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	NOP53 CEP95 SFMBT2 RPL13 PNMA8B	3.71e-04	361	59	5	26167880
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX5 DUX3	3.79e-04	17	59	2	11245978
Pubmed	Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.	BMP8B BMP8A	3.79e-04	17	59	2	14736746
Pubmed	Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.	HHIP FOXF2	3.79e-04	17	59	2	25356765
Pubmed	Leber Congenital Amaurosis – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	GUCY2D TULP1	3.79e-04	17	59	2	20301475
Pubmed	ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development.	FOXF2 FOXD1	3.79e-04	17	59	2	36196625
Pubmed	Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.	EZH2 CBX2	3.79e-04	17	59	2	12589020
Pubmed	Dysfunction of programmed embryo senescence is linked to genetic developmental defects.	BMP8B BMP8A	4.25e-04	18	59	2	37017267
Pubmed	Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.	HHIP FOXF2	4.25e-04	18	59	2	30352852
Pubmed	Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.	FOXF2 FOXD1	4.75e-04	19	59	2	15107405
Pubmed	A novel common variant in DCST2 is associated with length in early life and height in adulthood.	HHIP HMGA2	5.27e-04	20	59	2	25281659
Pubmed	Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.	MTA2 NCAPD3 PHRF1 CMAS	5.59e-04	222	59	4	35941108
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	MTA2 NCAPD3 HMGA2 EZH2 CBX2	5.64e-04	396	59	5	26687479
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MTA2 ZNF469 PHRF1 ASH1L SRCAP CMAS LTBP4 BAHCC1	5.70e-04	1116	59	8	31753913
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MTA2 CCDC71L SRCAP EZH2 CMAS CBX2	5.72e-04	608	59	6	36089195
Pubmed	PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.	EZH2 CBX2	5.82e-04	21	59	2	18311137
Pubmed	Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development.	HHIP FOXD1	5.82e-04	21	59	2	28794157
Pubmed	Functional phylogeny relates LET-756 to fibroblast growth factor 9.	FGF3 FGF13	5.82e-04	21	59	2	15199049
Pubmed	Quantitative trait loci for body size components in mice.	CMAS GDF10 FOXD1	6.29e-04	98	59	3	16783635
Pubmed	An essential role for Polycomb Repressive Complex 2 in the mouse ovary.	HHIP EZH2 CBX2	6.29e-04	98	59	3	35084365
Pubmed	Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development.	FGF3 FGF13	6.39e-04	22	59	2	11900978
Pubmed	Expression of members of the Fgf family and their receptors during midfacial development.	FGF3 FGF13	6.39e-04	22	59	2	11165488
Pubmed	Genome-wide association analysis identifies 20 loci that influence adult height.	HHIP HMGA2	6.39e-04	22	59	2	18391952
Pubmed	Expression of FGFs during early mouse tongue development.	FGF3 FGF13	6.39e-04	22	59	2	26748348
Pubmed	Time-sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis.	SOST FGF3	6.39e-04	22	59	2	34254395
Pubmed	Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.	HHIP HMGA2	7.00e-04	23	59	2	19343178
Pubmed	Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms.	BMP8B FGF3	7.00e-04	23	59	2	20713518
Pubmed	Genome-wide Identification of Foxf2 Target Genes in Palate Development.	FOXF2 FOXD1	7.00e-04	23	59	2	32040930
Pubmed	Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.	FOXF2 FOXD1	7.00e-04	23	59	2	33898467
Pubmed	Identification of ten loci associated with height highlights new biological pathways in human growth.	HHIP HMGA2	7.00e-04	23	59	2	18391950
Pubmed	Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.	FGF3 FGF13	7.62e-04	24	59	2	12421715
Pubmed	Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview	GUCY2D TULP1	8.28e-04	25	59	2	30285347
Pubmed	FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation.	FGF3 FGF13	8.28e-04	25	59	2	20040496
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	ZNF689 FGF13 GDF10 FOXD1	8.83e-04	251	59	4	29031500
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	MRPL15 GPATCH1 PHRF1 UTP14A	9.92e-04	259	59	4	30404004
Pubmed	Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.	FGF3 FGF13 GDF10	1.05e-03	117	59	3	22682244
Pubmed	FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.	FGF3 FGF13	1.12e-03	29	59	2	21876757
Pubmed	A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.	HHIP FOXF2	1.12e-03	29	59	2	28797033
Pubmed	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.	SRCAP TULP1 JPH3	1.13e-03	120	59	3	21697133
Pubmed	Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors.	EZH2 FOXD1	1.19e-03	30	59	2	35830813
Pubmed	Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.	EZH2 CBX2	1.19e-03	30	59	2	37158107
Pubmed	Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development.	HMGA2 EZH2	1.27e-03	31	59	2	23895693
Pubmed	Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.	FGF3 FGF13	1.27e-03	31	59	2	16123981
Pubmed	PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.	MTA2 EZH2	1.27e-03	31	59	2	29846670
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	MTA2 NOP53 UTP14A CMAS RPL13	1.37e-03	483	59	5	36912080
Interaction	MPHOSPH10 interactions	NOP53 H1-7 UTP14A FGF3 FGF13 RPL13	1.06e-05	174	58	6	int:MPHOSPH10
Cytoband	Ensembl 112 genes in cytogenetic band chr16q24	MBTPS1 ZNF469 RPL13 JPH3	2.58e-05	136	57	4	chr16q24
Cytoband	16q24	MBTPS1 ZNF469	2.04e-04	17	57	2	16q24
Cytoband	16q24.3	RPL13 JPH3	1.93e-03	52	57	2	16q24.3
GeneFamily	Forkhead boxes	FOXE1 FOXF2 FOXD1	9.97e-05	43	38	3	508
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP8B BMP8A	2.34e-04	11	38	2	455
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	ASH1L EZH2	2.31e-03	34	38	2	487
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MTA2 EZH2	5.54e-03	53	38	2	532
GeneFamily	Endogenous ligands	BMP8B BMP8A GDF10	1.34e-02	237	38	3	542
GeneFamily	PHD finger proteins	PHRF1 ASH1L	1.53e-02	90	38	2	88
Coexpression	GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_DN	BMP8B TNFSF12 ASH1L BMP8A CMAS GDF10	4.41e-06	197	57	6	M7258
Coexpression	NABA_SECRETED_FACTORS	HHIP BMP8B TNFSF12 FGF3 FGF13 BMP8A GDF10	8.47e-06	338	57	7	MM17064
Coexpression	NABA_SECRETED_FACTORS	HHIP BMP8B TNFSF12 FGF3 FGF13 BMP8A GDF10	9.32e-06	343	57	7	M5883
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3	FOXE1 BMP8B FGF3 BMP8A SOWAHB FOXF2 JPH3	1.21e-05	357	57	7	MM828
Coexpression	GSE6259_BCELL_VS_CD4_TCELL_UP	MTA2 CCDC71L SOST MBD6 LTBP4	6.15e-05	192	57	5	M6732
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SOST HMGA2 GUCY2D TTLL10 CABLES1	1.12e-06	146	56	5	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B FGF13 GDF10 LTBP4 FOXF2	2.89e-06	177	56	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B FGF13 GDF10 LTBP4 FOXF2	2.89e-06	177	56	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	P03-Mesenchymal\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HHIP SCARF2 LTBP4 FOXF2 RPL13	4.64e-06	195	56	5	6180309c6ae278b996fd98c57461cbc129c028ba
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTC16 SCARF2 TTLL10 SRCAP	4.22e-05	154	56	4	ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BMP8B SOST TTLL10 CABLES1	5.02e-05	161	56	4	3e5a125a25d55bf27652f456239b00b315d54d91
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MBTPS1 ZNF469 TTLL10 CBX2	5.52e-05	165	56	4	6e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCell	IIF-Lymphocyte-T_NK-CD8_TCM\|IIF / Disease, Lineage and Cell Type	PDE3B FGF13 ADAM11 RPL13	5.65e-05	166	56	4	f3f289eb9fa52abf0226ec711302022a07a6f345
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	ZNF469 SCARF2 FOXD1 CBX2	5.79e-05	167	56	4	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	SOST BMP8A TTLL10 TULP1	5.79e-05	167	56	4	0614d077b47a87f726068615548d0b0a216627be
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOST GUCY2D GDF10 TULP1	5.92e-05	168	56	4	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SH3PXD2B SOST RPL13 CBX2	6.06e-05	169	56	4	a0681317867e31319210a23e56660a53f4529efe
ToppCell	IPF-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	SOST TTLL10 SFMBT2 CABLES1	6.94e-05	175	56	4	b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP\|lymph-node_spleen / Manually curated celltypes from each tissue	HHIP HMGA2 CBX2 BAHCC1	7.09e-05	176	56	4	de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	HHIP ZNF469 SH3PXD2B SCARF2	7.41e-05	178	56	4	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 GDF10 LTBP4 FOXD1	7.90e-05	181	56	4	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HHIP HMGA2 FOXF2 FOXD1	7.90e-05	181	56	4	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 GDF10 LTBP4 FOXD1	7.90e-05	181	56	4	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZNF469 GDF10 LTBP4 FOXD1	8.07e-05	182	56	4	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST SCARF2 GDF10 FOXD1	8.25e-05	183	56	4	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZNF469 GDF10 LTBP4 FOXD1	8.42e-05	184	56	4	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF2 GDF10 LTBP4 TULP1	8.42e-05	184	56	4	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF2 GDF10 LTBP4 TULP1	8.60e-05	185	56	4	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF2 GDF10 LTBP4 TULP1	8.60e-05	185	56	4	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 GDF10 LTBP4	8.60e-05	185	56	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 GDF10 LTBP4	8.60e-05	185	56	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HHIP HMGA2 LTBP4 RPL13	8.78e-05	186	56	4	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 GDF10 LTBP4	8.78e-05	186	56	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2B GDF10 LTBP4 FOXF2	8.96e-05	187	56	4	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2B GDF10 LTBP4 FOXF2	8.96e-05	187	56	4	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3PXD2B GDF10 LTBP4 FOXF2	8.96e-05	187	56	4	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST DGKZ SOWAHB PNMA8B	9.15e-05	188	56	4	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 LTBP4 FOXF2	9.34e-05	189	56	4	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 LTBP4 FOXF2	9.34e-05	189	56	4	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HHIP SCARF2 LTBP4 FOXF2	9.34e-05	189	56	4	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HHIP FAM124A FGF13 LTBP4	9.53e-05	190	56	4	c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HHIP GDF10 LTBP4 PNMA8B	9.73e-05	191	56	4	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPD3 EGR4 FAM124A EZH2	9.73e-05	191	56	4	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	facs-Trachea-nan-18m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF12 FAM124A GDF10 LTBP4	9.73e-05	191	56	4	783e8c436de90623bb1bc4117270d60c8c8a9461
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCARF2 GDF10 LTBP4 PNMA8B	9.92e-05	192	56	4	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP SCARF2 GDF10 LTBP4	1.01e-04	193	56	4	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 MBTPS1 PHRF1 DGKZ	1.03e-04	194	56	4	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HHIP TNFSF12 GDF10 LTBP4	1.03e-04	194	56	4	3d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCARF2 GDF10 FOXF2 PNMA8B	1.03e-04	194	56	4	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 MBTPS1 PHRF1 DGKZ	1.03e-04	194	56	4	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 MBTPS1 PHRF1 DGKZ	1.03e-04	194	56	4	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HHIP TNFSF12 GDF10 LTBP4	1.03e-04	194	56	4	ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE3B TTC16 NOP53 RPL13	1.05e-04	195	56	4	82561f6ed75ee33c2581fb25bd0997a9f0538cd8
ToppCell	distal-1-Hematologic-CD4+_Naive_T\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NOP53 SFMBT2 RPL13 CBX2	1.07e-04	196	56	4	14845d46a362ad88e71a2090a39b817f9c46619e
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC71L HMGA2 FAM124A LTBP4	1.10e-04	197	56	4	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FOXE1 HMGA2 FGF13 FOXD1	1.12e-04	198	56	4	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	11.5-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	GDF10 LTBP4 FOXF2 RPL13	1.12e-04	198	56	4	5c606d881f151404287d9b43c9490e9bb486ef54
ToppCell	distal-Hematologic-CD4+_Naive_T-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NOP53 SFMBT2 RPL13 CBX2	1.14e-04	199	56	4	0d2ef4195736d0a5cd0758a8b804a0ab385ffb9a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial\|5w / Sample Type, Dataset, Time_group, and Cell type.	NOP53 GDF10 RPL13 FOXD1	1.16e-04	200	56	4	69707f9576d326a06faac49701ef5cd632e760f6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial-Proteoglycan-expressing_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	NOP53 GDF10 RPL13 FOXD1	1.16e-04	200	56	4	f94381d0a3b5b81cdbb13b75fc0e4910cbd70382
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-Unfolded_protein_responsible_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	BMP8B UTP14A CBX2	3.31e-04	107	56	3	7fee0193ee02e9cc62f506660ea7ec23fb4d0c84
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AHRR GPATCH1 SOWAHB	4.30e-04	117	56	3	240cd636d1f5d3f270825ace02126fae993f5802
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ZNF469 AHRR JPH3	4.51e-04	119	56	3	d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ZNF469 AHRR JPH3	4.51e-04	119	56	3	9e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCell	control-Plasmablast\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BMP8B NOP53 FOXD1	5.84e-04	130	56	3	9fe3c5be8488d341cff38757daf7856c112410d0
ToppCell	PBMC-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	ZNF469 SCARF2 GUCY2D	6.24e-04	133	56	3	e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCell	TCGA-Uvea\|World / Sample_Type by Project: Shred V9	ZNF469 AHRR CABLES1	7.40e-04	141	56	3	015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D3\|390C / Donor, Lineage, Cell class and subclass (all cells)	BMP8B SOST TTLL10	7.70e-04	143	56	3	10473c0f030d5ff760263042dc4b584787cb4a7f
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|368C / Donor, Lineage, Cell class and subclass (all cells)	TTC16 TTLL10 SRCAP	8.34e-04	147	56	3	3ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SCARF2 TULP1 FOXD1	8.68e-04	149	56	3	3980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HHIP BMP8B SRCAP	8.68e-04	149	56	3	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HHIP BMP8B SRCAP	8.68e-04	149	56	3	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	(00)_Basal\|World / shred by cell type and Timepoint	NOP53 LTBP4 RPL13	8.68e-04	149	56	3	49e39206f37cee124ca4763c79425b805e50624b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF469 SCARF2 GUCY2D	9.37e-04	153	56	3	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NCAPD3 SRCAP CBX2	9.37e-04	153	56	3	991782d111d66e25b40319d4e6dea40f2c2c0805
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF469 SCARF2 GUCY2D	9.37e-04	153	56	3	f17f62646633cf95c810dcd5328978058741b276
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXE1 GDF10 TULP1	9.37e-04	153	56	3	92a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SCARF2 TULP1 FOXD1	9.54e-04	154	56	3	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	facs-Skin-nan-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST SOWAHB RPL13	9.72e-04	155	56	3	fa2776d258e0420b2895de1008e292ad7725dac0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP8B SOST TTC16	1.01e-03	157	56	3	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP8B SOST TTC16	1.01e-03	157	56	3	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP8B SOST TTC16	1.01e-03	157	56	3	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HMGA2 CABLES1 CBX2	1.03e-03	158	56	3	4f3ea658e032555c2098d016475381c8d1071699
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PDE3B GDF10 FOXF2	1.07e-03	160	56	3	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PDE3B GDF10 FOXF2	1.07e-03	160	56	3	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	Healthy/Control-CD8+_T_naive\|Healthy/Control / Disease group and Cell class	PDE3B GDF10 RPL13	1.07e-03	160	56	3	e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SCARF2 FGF13 BMP8A	1.08e-03	161	56	3	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	Healthy_donor-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	PDE3B GDF10 RPL13	1.08e-03	161	56	3	8a61395af33132783a0a37956c6f821aba5d3b1e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 PDE3B FAM124A	1.08e-03	161	56	3	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	Bronchial_Biopsy-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	ZNF469 HMGA2 LSM11	1.10e-03	162	56	3	985adca17b0c99563feef7910f3da5df31e636b6
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HMGA2 CABLES1 CBX2	1.10e-03	162	56	3	233011408f022647932c81ebab78f9813e3c6833
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	GUCY2D FAM124A TTLL10	1.12e-03	163	56	3	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BMP8A LTBP4 FOXF2	1.12e-03	163	56	3	8f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ZNF469 EGR4 SCARF2	1.14e-03	164	56	3	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDE3B NOP53 RPL13	1.16e-03	165	56	3	4edc9714185a7519a7044487a3d6ea845131b851
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP4 FOXF2 PNMA8B	1.16e-03	165	56	3	01c6355177d79b4523c8b20366e20b2b62c6d08d
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 EGR4 GUCY2D	1.16e-03	165	56	3	60b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDE3B NOP53 RPL13	1.16e-03	165	56	3	fd1d38b97564c1f64f5c7246dcec96d60364b7b2
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	HMGA2 EGR4 CABLES1	1.18e-03	166	56	3	ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-\|GI_small-bowel / Manually curated celltypes from each tissue	DGKZ BMP8A CABLES1	1.21e-03	167	56	3	7ff186b2bed3b0de93addb3b0ae5a2c6e44ddfb2
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	BMP8B SOST TTLL10	1.23e-03	168	56	3	6501495b7ad252af330b18011696c43031541018
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-CD4_CTL\|ICU-NoSEP / Disease, Lineage and Cell Type	TTC16 LTBP4 FOXD1	1.25e-03	169	56	3	cbda36f32bd78322dcfe303a44413415d08e5ea3
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 GDF10 PNMA8B	1.25e-03	169	56	3	031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCAPD3 GPATCH1 UTP14A	1.27e-03	170	56	3	12aa9bdb18f3bf6da2a25984d08fe9497e5570ed
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HHIP LTBP4 FOXF2	1.27e-03	170	56	3	b5b47fe42617a4c2ebb49c8ed55db3926213a75a
Drug	AC1L9Q5W	BMP8B SOST FGF3 BMP8A GDF10	6.29e-06	106	56	5	CID000452221
Disease	birth weight	HHIP ZNF469 HMGA2 TNFSF12 FGF3 TULP1 CABLES1	1.03e-05	399	56	7	EFO_0004344
Disease	papillary thyroid carcinoma	FOXE1 SOWAHB	2.31e-04	12	56	2	EFO_0000641
Disease	peak expiratory flow	HHIP HMGA2 SCARF2 BMP8A LTBP4 RPL13	3.56e-04	498	56	6	EFO_0009718
Disease	Leber congenital amaurosis	GUCY2D TULP1	4.17e-04	16	56	2	cv:C0339527
Disease	forced expiratory volume	HHIP HMGA2 TNFSF12 SCARF2 CEP95 BMP8A CABLES1	7.07e-04	789	56	7	EFO_0004314
Disease	Leber Congenital Amaurosis	GUCY2D TULP1	7.98e-04	22	56	2	C0339527
Disease	infant body height	HHIP HMGA2	8.72e-04	23	56	2	EFO_0006785
Disease	diabetes mellitus (implicated_via_orthology)	BMP8B BMP8A	1.12e-03	26	56	2	DOID:9351 (implicated_via_orthology)
Disease	pulse pressure measurement	CCDC71L HMGA2 TNFSF12 TTC16 H1-7 FGF3 SRCAP GDF10 FOXD1	1.15e-03	1392	56	9	EFO_0005763
Disease	resting heart rate, chronic obstructive pulmonary disease	HMGA2 BMP8A	1.49e-03	30	56	2	EFO_0000341, EFO_0004351
Disease	smoking behavior, BMI-adjusted waist circumference	HHIP HMGA2 CABLES1	1.63e-03	122	56	3	EFO_0004318, EFO_0007789
Disease	complex trait	HHIP ZNF689 BMP8A CABLES1	1.76e-03	271	56	4	EFO_0010578

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKRRRPLQKQRPAVG	AHRR	16	A9YTQ3
PDARRRKTPQGPGRK	SLC4A2	91	P04920
RSPARRGPGRPRKRK	BAHCC1	1476	Q9P281
VKRRPGRPRKCPLQA	ASH1L	1846	Q9NR48
EAEKPAPRRAPKRRQ	DPEP2NB	76	A0A0U1RQF7
AQSAPPNRPRLRRKR	ADAM11	211	O75078
RRAARRPNLPLKVKP	MTA2	626	O94776
RRRKRFKRQPLLPPN	FOXD1	216	Q16676
PRARPGRPAKNKRRK	MBD6	986	Q96DN6
DPALRRRRRGPRNKK	NOP53	31	Q9NZM5
RRGPGRSRKAPRNVL	LSM11	131	P83369
SRPKRRKPRVKRPQL	MBTPS1	1026	Q14703
IPPERRRKLEKARPG	GUCY2D	1086	Q02846
PWPGRRDPQKGRRKR	DUX5	111	Q96PT3
PPGKGVQPRRRRQKQ	FGF3	201	P11487
SPFRALKPRPGRKDR	GDF10	326	P55107
ASRRRRKPPKGAQPA	FAM124A	86	Q86V42
VGPRVKRRPRRQKPD	GPATCH1	171	Q9BRR8
ERIKTPPKRPGGRRR	EZH2	341	Q15910
AKRRRRCLDPTKAPP	FBXO46	131	Q6PJ61
PKPPRRKSRRRIFCQ	PDE3B	1046	Q13370
QRPLTPRTPARRKRK	PHRF1	326	Q9P1Y6
PTPFPQAKARRKGRR	EGR4	451	Q05215
RARPRAKEPPCARAK	H1-7	191	Q75WM6
EVQNRKRGKRPRGRP	CBX2	66	Q14781
PPRKPRMDPRRRQAA	CABLES1	51	Q8TDN4
TPRAVRPLRRRQPKK	BMP8A	261	Q7Z5Y6
RPLRRRQPKKSNELP	BMP8A	266	Q7Z5Y6
PRTRKPPKGKRNENR	CEP95	331	Q96GE4
PWPGRRDPQKGRRKR	DUX3	111	Q96PT4
QEARALLKRRRPRGP	LTBP4	116	Q8N2S1
LFGSKKRRRRRPEPQ	FGF13	51	Q92913
APAPQKRGRGRPRKQ	HMGA2	21	P52926
GARAAAARRRKPRPP	CCDC71L	136	Q8N9Z2
PEPDKAPRRLNKRRF	DGKZ	31	Q13574
TPRAVRPLRRRQPKK	BMP8B	261	P34820
RPLRRRQPKKSNELP	BMP8B	266	P34820
RRRQAPAGSPRGLRK	RXYLT1	31	Q9Y2B1
RKARQAKARRIAPRP	RPL13	36	P26373
RRPRGFRRKCQALKP	FOXF2	191	Q12947
PGSKKPERRPRGRRR	MRPL15	31	Q9P015
GGRRRKRPLQRGKPP	FOXE1	41	O00358
RGRPSRGRPPKLQRN	CMAS	16	Q8NFW8
RKPRAKRARTAPRGL	PNMA8B	531	Q9ULN7
VKRRRGRPPKKNRSP	SRCAP	2856	Q6ZRS2
LSPVEKRRRGRPPKA	SRCAP	2931	Q6ZRS2
KRRRGRPPKARDLPI	SRCAP	2936	Q6ZRS2
AARPQKGRKPRPRAR	SOST	186	Q9BQB4
KRSRRPPRSRKPSKA	SOWAHB	521	A6NEL2
RRRCLNGNPPKRLKR	HHIP	36	Q96QV1
ANPGRHRKRGKPPRR	NCAPD3	171	P42695
PKQRPAPAQRLRKKR	TULP1	31	O00294
KQRSPKMRQRPPPRR	SH3PXD2B	336	A1X283
PRPRRELSLGRKKAP	SCARF2	476	Q96GP6
PDSGHPKPARRRKRR	SFMBT2	681	Q5VUG0
RRPRPRLARPRAGQK	SCAND2P	266	Q9GZW5
RRRFLIKAPEGPPRK	UTP14A	646	Q9BVJ6
RRRRLPPRKDPRKRK	ZNF469	1026	Q96JG9
ARPSRKRGRRPRALK	ZNF689	16	Q96CS4
NRLVRPRRSAPKGRK	TNFSF12	86	O43508
PRRSAPKGRKTRARR	TNFSF12	91	O43508
RSPRQRPRKVKAARG	TTC16	766	Q8NEE8
GFKRGKRPRIQQRPR	TTLL10	21	Q6ZVT0
SGRKQPGNPKPRERR	JPH3	561	Q8WXH2