Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

1.07e-075453GO:0030156
GeneOntologyMolecularFunctionKrueppel-associated box domain binding

HDAC1 HDAC2

1.49e-053452GO:0035851
GeneOntologyMolecularFunctionprotein decrotonylase activity

HDAC1 HDAC2

4.94e-055452GO:0160008
GeneOntologyMolecularFunctionhistone decrotonylase activity

HDAC1 HDAC2

4.94e-055452GO:0160009
GeneOntologyMolecularFunctionchromatin binding

SRF FOXO3 SALL1 RNF168 MBD5 NFAT5 HDAC1 HDAC2

2.17e-04739458GO:0003682
GeneOntologyMolecularFunctiontranscription factor binding

SRF FOXO3 HNF1B SALL1 NFAT5 LRIF1 HDAC1 HDAC2

2.46e-04753458GO:0008134
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXO3 HNF1B HDAC1 HDAC2

2.76e-04140454GO:0001221
GeneOntologyMolecularFunctionATP-dependent activity

NAV2 KIF18A CHD9 DNA2 DNAH5 KIF26B SMCHD1

4.13e-04614457GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

NAV2 KIF18A CHD9 DNA2 DNAH5 SMCHD1

4.40e-04441456GO:0016887
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1D CACNA1S

4.44e-0414452GO:0008331
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF18A DNAH5 KIF26B

5.27e-0470453GO:0003777
GeneOntologyMolecularFunctionchromatin DNA binding

SRF FOXO3 HDAC1 HDAC2

5.38e-04167454GO:0031490
GeneOntologyMolecularFunctionhistone deacetylase activity

HDAC1 HDAC2

1.33e-0324452GO:0004407
GeneOntologyMolecularFunctionnucleosome binding

RNF168 HDAC1 HDAC2

1.40e-0398453GO:0031491
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

HDAC1 HDAC2

1.44e-0325452GO:0033558
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

SRF FOXO3 HNF1B SALL1 MGA NFAT5 MYEF2 HDAC1 HDAC2

1.59e-031244459GO:0000978
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

NAV2 KIF18A CHD9 DNA2 DNAH5 SMCHD1 MX2

1.62e-03775457GO:0017111
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

SRF FOXO3 HNF1B SALL1 MGA NFAT5 MYEF2 HDAC1 HDAC2

1.84e-031271459GO:0000987
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF18A DNAH5 KIF26B

2.38e-03118453GO:0003774
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

SRF SALL1 LRIF1 HDAC1 HDAC2

2.38e-03417455GO:0061629
GeneOntologyMolecularFunctionpyrophosphatase activity

NAV2 KIF18A CHD9 DNA2 DNAH5 SMCHD1 MX2

2.54e-03839457GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NAV2 KIF18A CHD9 DNA2 DNAH5 SMCHD1 MX2

2.55e-03840457GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NAV2 KIF18A CHD9 DNA2 DNAH5 SMCHD1 MX2

2.55e-03840457GO:0016818
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

NAV2 CHD9 DNA2

2.93e-03127453GO:0008094
GeneOntologyMolecularFunctionNF-kappaB binding

HDAC1 HDAC2

2.98e-0336452GO:0051059
GeneOntologyMolecularFunctiondeacetylase activity

HDAC1 HDAC2

3.67e-0340452GO:0019213
GeneOntologyMolecularFunctionhistone deacetylase binding

SRF HDAC1 HDAC2

4.42e-03147453GO:0042826
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

SRF FOXO3 HNF1B SALL1 MGA NFAT5 MYEF2 HDAC1 HDAC2

4.66e-031459459GO:0000977
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1D CACNA1S

4.83e-0346452GO:0005245
GeneOntologyMolecularFunctionhelicase activity

NAV2 CHD9 DNA2

5.41e-03158453GO:0004386
GeneOntologyMolecularFunctiontranscription corepressor binding

HDAC1 HDAC2

7.83e-0359452GO:0001222
GeneOntologyMolecularFunctionDNA helicase activity

NAV2 DNA2

8.62e-0362452GO:0003678
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

SRF SALL1 LRIF1 HDAC1 HDAC2

9.66e-03582455GO:0140297
GeneOntologyMolecularFunctionnucleosomal DNA binding

HDAC1 HDAC2

1.00e-0267452GO:0031492
GeneOntologyBiologicalProcessureteric bud elongation

HNF1B SALL1 KIF26B

5.39e-078453GO:0060677
GeneOntologyBiologicalProcesseyelid development in camera-type eye

SRF HDAC1 HDAC2

5.33e-0616453GO:0061029
GeneOntologyBiologicalProcessbrain development

SRF NAV2 FOXO3 HNF1B SALL1 DNAH5 GPR158 HDAC1 HDAC2 CNTNAP2

1.26e-058594510GO:0007420
GeneOntologyBiologicalProcessureteric bud invasion

SALL1 KIF26B

1.39e-053452GO:0072092
GeneOntologyBiologicalProcesshead development

SRF NAV2 FOXO3 HNF1B SALL1 DNAH5 GPR158 HDAC1 HDAC2 CNTNAP2

2.26e-059194510GO:0060322
GeneOntologyBiologicalProcessnegative regulation of stem cell population maintenance

HNF1B HDAC1 HDAC2

2.44e-0526453GO:1902455
GeneOntologyBiologicalProcessfungiform papilla formation

HDAC1 HDAC2

2.78e-054452GO:0061198
GeneOntologyBiologicalProcessmetanephric renal vesicle formation

SALL1 KIF26B

2.78e-054452GO:0072093
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

RIMBP3 RIMBP3C RIMBP3B

6.59e-0536453GO:0007274
GeneOntologyBiologicalProcessfungiform papilla morphogenesis

HDAC1 HDAC2

6.94e-056452GO:0061197
GeneOntologyBiologicalProcesshair follicle placode formation

HDAC1 HDAC2

6.94e-056452GO:0060789
GeneOntologyBiologicalProcessgerm cell development

RIMBP3 FOXO3 UBE2J1 RIMBP3C RIMBP3B SMCHD1 KNL1

7.67e-05482457GO:0007281
GeneOntologyBiologicalProcessfungiform papilla development

HDAC1 HDAC2

9.71e-057452GO:0061196
GeneOntologyBiologicalProcessmesenchymal stem cell maintenance involved in nephron morphogenesis

HNF1B SALL1

9.71e-057452GO:0072038
GeneOntologyBiologicalProcessrenal vesicle formation

SALL1 KIF26B

1.29e-048452GO:0072033
GeneOntologyBiologicalProcessdevelopmental growth

SRF FOXO3 HNF1B CYFIP1 SALL1 MBD5 KIF26B HDAC2 CNTNAP2

1.30e-04911459GO:0048589
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

RIMBP3 FOXO3 UBE2J1 RIMBP3C RIMBP3B SMCHD1 KNL1

1.34e-04527457GO:0022412
GeneOntologyBiologicalProcesscell fate specification

HNF1B MGA HDAC1 HDAC2

1.49e-04123454GO:0001708
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SRF FOXO3 JAK3 HNF1B SSBP2 IGBP1 SALL1 MGA NFAT5 HDAC1 HDAC2

1.51e-0413904511GO:0045944
GeneOntologyBiologicalProcessstem cell population maintenance

FOXO3 HNF1B SALL1 HDAC1 HDAC2

1.61e-04237455GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

FOXO3 HNF1B SALL1 HDAC1 HDAC2

1.78e-04242455GO:0098727
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

RIMBP3 FOXO3 UBE2J1 KIF18A RIMBP3C RIMBP3B SPATA31A6 SMCHD1 HDAC2 KNL1

2.02e-0411944510GO:0048609
GeneOntologyBiologicalProcesscentral nervous system development

SRF NAV2 FOXO3 HNF1B SALL1 DNAH5 GPR158 HDAC1 HDAC2 CNTNAP2

2.06e-0411974510GO:0007417
GeneOntologyBiologicalProcessgamete generation

RIMBP3 FOXO3 UBE2J1 KIF18A RIMBP3C RIMBP3B SPATA31A6 SMCHD1 KNL1

2.28e-04982459GO:0007276
GeneOntologyBiologicalProcessspermatid development

RIMBP3 UBE2J1 RIMBP3C RIMBP3B KNL1

2.57e-04262455GO:0007286
GeneOntologyBiologicalProcessprotein-DNA complex organization

CHD9 HNF1B RNF168 NFAT5 TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

2.59e-04999459GO:0071824
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

RIMBP3 FOXO3 UBE2J1 KIF18A RIMBP3C HNF1B RIMBP3B SPATA31A6 SMCHD1 KNL1

2.66e-0412354510GO:0003006
GeneOntologyBiologicalProcesstongue morphogenesis

HDAC1 HDAC2

3.03e-0412452GO:0043587
GeneOntologyBiologicalProcessspermatid differentiation

RIMBP3 UBE2J1 RIMBP3C RIMBP3B KNL1

3.05e-04272455GO:0048515
GeneOntologyBiologicalProcessheterochromatin formation

LRIF1 SMCHD1 HDAC1 HDAC2

4.35e-04163454GO:0031507
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

SRF HNF1B CYFIP1 SALL1 KIF26B

4.70e-04299455GO:0060560
GeneOntologyBiologicalProcessmetanephric renal vesicle morphogenesis

SALL1 KIF26B

4.80e-0415452GO:0072283
GeneOntologyBiologicalProcessectodermal placode morphogenesis

HDAC1 HDAC2

5.48e-0416452GO:0071697
GeneOntologyBiologicalProcessectodermal placode formation

HDAC1 HDAC2

5.48e-0416452GO:0060788
GeneOntologyBiologicalProcessembryonic digit morphogenesis

SALL1 HDAC1 HDAC2

5.64e-0474453GO:0042733
GeneOntologyBiologicalProcessureteric bud morphogenesis

HNF1B SALL1 KIF26B

5.64e-0474453GO:0060675
GeneOntologyBiologicalProcesseye development

SRF COL5A2 CACNA1S CRYBG3 HDAC1 HDAC2

5.81e-04480456GO:0001654
GeneOntologyBiologicalProcesscircadian regulation of gene expression

HNF1B HDAC1 HDAC2

5.87e-0475453GO:0032922
GeneOntologyBiologicalProcessvisual system development

SRF COL5A2 CACNA1S CRYBG3 HDAC1 HDAC2

6.00e-04483456GO:0150063
GeneOntologyBiologicalProcesschromatin organization

CHD9 RNF168 NFAT5 TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

6.34e-04896458GO:0006325
GeneOntologyBiologicalProcesssensory system development

SRF COL5A2 CACNA1S CRYBG3 HDAC1 HDAC2

6.54e-04491456GO:0048880
GeneOntologyBiologicalProcessmesonephric tubule morphogenesis

HNF1B SALL1 KIF26B

6.58e-0478453GO:0072171
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

HNF1B HDAC1 HDAC2

6.58e-0478453GO:2000036
GeneOntologyBiologicalProcessectodermal placode development

HDAC1 HDAC2

6.96e-0418452GO:0071696
GeneOntologyBiologicalProcessrenal vesicle morphogenesis

SALL1 KIF26B

6.96e-0418452GO:0072077
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

RNF168 LRIF1 SMCHD1 HDAC1 HDAC2

7.35e-04330455GO:0040029
GeneOntologyBiologicalProcesstelencephalon development

SRF SALL1 DNAH5 HDAC1 HDAC2

7.55e-04332455GO:0021537
GeneOntologyBiologicalProcessrenal vesicle development

SALL1 KIF26B

7.77e-0419452GO:0072087
GeneOntologyBiologicalProcessregulation of miRNA transcription

SRF FOXO3 HDAC2

7.89e-0483453GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

SRF FOXO3 HDAC2

8.17e-0484453GO:0061614
GeneOntologyBiologicalProcessnephron tubule morphogenesis

HNF1B SALL1 KIF26B

9.05e-0487453GO:0072078
GeneOntologyBiologicalProcessendoderm development

COL5A2 HNF1B HDAC1

9.35e-0488453GO:0007492
GeneOntologyBiologicalProcesssensory organ development

SRF COL5A2 CACNA1S CRYBG3 SMCHD1 HDAC1 HDAC2

9.50e-04730457GO:0007423
GeneOntologyBiologicalProcessresponse to caffeine

CACNA1S HDAC2

9.52e-0421452GO:0031000
GeneOntologyBiologicalProcessnephron epithelium morphogenesis

HNF1B SALL1 KIF26B

9.67e-0489453GO:0072088
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

LRIF1 SMCHD1 HDAC1 HDAC2

9.90e-04203454GO:0045814
GeneOntologyBiologicalProcessnephron morphogenesis

HNF1B SALL1 KIF26B

1.03e-0391453GO:0072028
GeneOntologyBiologicalProcesschromatin remodeling

CHD9 RNF168 NFAT5 LRIF1 SMCHD1 HDAC1 HDAC2

1.04e-03741457GO:0006338
GeneOntologyBiologicalProcessdosage compensation by inactivation of X chromosome

LRIF1 SMCHD1

1.05e-0322452GO:0009048
GeneOntologyBiologicalProcessrhythmic process

FOXO3 HNF1B HDAC1 HDAC2 CNTNAP2

1.08e-03360455GO:0048511
GeneOntologyBiologicalProcessrenal tubule morphogenesis

HNF1B SALL1 KIF26B

1.10e-0393453GO:0061333
GeneOntologyBiologicalProcessmetanephric nephron morphogenesis

SALL1 KIF26B

1.14e-0323452GO:0072273
GeneOntologyBiologicalProcessmuscle system process

SRF FOXO3 CACNA1D CACNA1S CAMK2G HDAC2

1.15e-03547456GO:0003012
GeneOntologyBiologicalProcessmetanephros development

HNF1B SALL1 KIF26B

1.17e-0395453GO:0001656
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

FOXO3 HNF1B SALL1 HDAC1 HDAC2

1.20e-03368455GO:0030111
GeneOntologyBiologicalProcessgrowth

SRF FOXO3 HNF1B CYFIP1 SALL1 MBD5 KIF26B HDAC2 CNTNAP2

1.20e-031235459GO:0040007
GeneOntologyBiologicalProcessmale gamete generation

RIMBP3 UBE2J1 KIF18A RIMBP3C RIMBP3B SPATA31A6 KNL1

1.22e-03762457GO:0048232
GeneOntologyBiologicalProcesssex-chromosome dosage compensation

LRIF1 SMCHD1

1.25e-0324452GO:0007549
GeneOntologyBiologicalProcessgrowth hormone receptor signaling pathway

JAK3 MBD5

1.46e-0326452GO:0060396
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

SRF FOXO3 HDAC2

1.47e-03103453GO:2000628
GeneOntologyBiologicalProcessstriated muscle cell differentiation

SRF CACNA1S HDAC1 HDAC2 CNTNAP2

1.56e-03391455GO:0051146
GeneOntologyBiologicalProcesstongue development

HDAC1 HDAC2

1.58e-0327452GO:0043586
GeneOntologyBiologicalProcesscellular response to growth hormone stimulus

JAK3 MBD5

1.58e-0327452GO:0071378
GeneOntologyBiologicalProcessureteric bud development

HNF1B SALL1 KIF26B

1.64e-03107453GO:0001657
GeneOntologyBiologicalProcesshippocampus development

SRF HDAC1 HDAC2

1.69e-03108453GO:0021766
GeneOntologyBiologicalProcessmesonephric tubule development

HNF1B SALL1 KIF26B

1.78e-03110453GO:0072164
GeneOntologyBiologicalProcessmesonephric epithelium development

HNF1B SALL1 KIF26B

1.78e-03110453GO:0072163
GeneOntologyBiologicalProcessnephron tubule development

HNF1B SALL1 KIF26B

1.78e-03110453GO:0072080
GeneOntologyBiologicalProcessmetanephros morphogenesis

SALL1 KIF26B

1.82e-0329452GO:0003338
GeneOntologyBiologicalProcessregulation of cell fate specification

HDAC1 HDAC2

1.82e-0329452GO:0042659
GeneOntologyBiologicalProcesskidney morphogenesis

HNF1B SALL1 KIF26B

1.83e-03111453GO:0060993
GeneOntologyBiologicalProcesssexual reproduction

RIMBP3 FOXO3 UBE2J1 KIF18A RIMBP3C RIMBP3B SPATA31A6 SMCHD1 KNL1

1.83e-031312459GO:0019953
GeneOntologyBiologicalProcessmesonephros development

HNF1B SALL1 KIF26B

1.92e-03113453GO:0001823
GeneOntologyBiologicalProcesscircadian rhythm

HNF1B HDAC1 HDAC2 CNTNAP2

2.06e-03248454GO:0007623
GeneOntologyBiologicalProcessrenal tubule development

HNF1B SALL1 KIF26B

2.07e-03116453GO:0061326
GeneOntologyBiologicalProcessnegative regulation of miRNA transcription

SRF HDAC2

2.08e-0331452GO:1902894
GeneOntologyBiologicalProcessregulation of developmental growth

SRF HNF1B CYFIP1 MBD5 HDAC2

2.16e-03421455GO:0048638
GeneOntologyBiologicalProcessskeletal muscle adaptation

CACNA1S CAMK2G

2.21e-0332452GO:0043501
GeneOntologyCellularComponentCHD-type complex

SALL1 HDAC1 HDAC2

6.21e-0617453GO:0090545
GeneOntologyCellularComponentNuRD complex

SALL1 HDAC1 HDAC2

6.21e-0617453GO:0016581
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

2.94e-0528453GO:0002177
GeneOntologyCellularComponenthistone deacetylase complex

SALL1 TRRAP HDAC1 HDAC2

3.34e-0585454GO:0000118
GeneOntologyCellularComponenttranscription regulator complex

FOXO3 HNF1B SALL1 MGA NFAT5 TRRAP HDAC1 HDAC2

3.54e-05596458GO:0005667
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SALL1 TRRAP HDAC1 HDAC2

5.39e-0596454GO:0070603
GeneOntologyCellularComponentBarr body

LRIF1 SMCHD1

1.26e-048452GO:0001740
GeneOntologyCellularComponentATPase complex

SALL1 TRRAP HDAC1 HDAC2

1.70e-04129454GO:1904949
GeneOntologyCellularComponentnuclear chromosome

TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

2.09e-04254455GO:0000228
GeneOntologyCellularComponentchromosomal region

KIF18A DNA2 LRIF1 SMCHD1 HDAC2 KNL1

2.70e-04421456GO:0098687
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1D CACNA1S

2.95e-0412452GO:1990454
GeneOntologyCellularComponentX chromosome

LRIF1 SMCHD1

3.48e-0413452GO:0000805
GeneOntologyCellularComponentchromosome, telomeric region

DNA2 LRIF1 SMCHD1 HDAC2

5.53e-04176454GO:0000781
GeneOntologyCellularComponentRNA polymerase II transcription repressor complex

FOXO3 HDAC2

6.04e-0417452GO:0090571
GeneOntologyCellularComponentchromocenter

SALL1 MBD5

6.78e-0418452GO:0010369
GeneOntologyCellularComponentsupramolecular fiber

CACNA1D COL5A2 KIF18A CACNA1S IGBP1 EIF3A DNAH5 KIF26B MX2

7.87e-041179459GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CACNA1D COL5A2 KIF18A CACNA1S IGBP1 EIF3A DNAH5 KIF26B MX2

8.26e-041187459GO:0099081
GeneOntologyCellularComponenttranscription repressor complex

FOXO3 HDAC1 HDAC2

8.71e-0487453GO:0017053
GeneOntologyCellularComponentmicrotubule

KIF18A IGBP1 EIF3A DNAH5 KIF26B MX2

9.35e-04533456GO:0005874
GeneOntologyCellularComponentSin3-type complex

HDAC1 HDAC2

1.02e-0322452GO:0070822
GeneOntologyCellularComponentheterochromatin

SALL1 HDAC1 HDAC2

1.34e-03101453GO:0000792
GeneOntologyCellularComponentchromatin

SRF FOXO3 HNF1B SALL1 MGA NFAT5 TRRAP HDAC1 HDAC2

3.78e-031480459GO:0000785
GeneOntologyCellularComponentsex chromosome

LRIF1 SMCHD1

4.05e-0344452GO:0000803
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1D CACNA1S

4.42e-0346452GO:0005891
MousePhenoectopic manchette

RIMBP3 RIMBP3C RIMBP3B

1.61e-0519373MP:0009377
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B

2.20e-0521373MP:0008893
DomainHis_deacetylse_1

HDAC1 HDAC2

3.24e-054442IPR003084
DomainVDCC_L_a1su

CACNA1D CACNA1S

3.24e-054442IPR005446
DomainGPHH_dom

CACNA1D CACNA1S

1.13e-047442IPR031649
DomainVDCC_a1su_IQ

CACNA1D CACNA1S

1.13e-047442IPR014873
DomainCa_chan_IQ

CACNA1D CACNA1S

1.13e-047442SM01062
DomainCa_chan_IQ

CACNA1D CACNA1S

1.13e-047442PF08763
DomainGPHH

CACNA1D CACNA1S

1.13e-047442PF16905
DomainVDCCAlpha1

CACNA1D CACNA1S

2.41e-0410442IPR002077
DomainHis_deacetylse_dom

HDAC1 HDAC2

2.94e-0411442IPR023801
DomainHist_deacetyl

HDAC1 HDAC2

2.94e-0411442PF00850
Domain-

HDAC1 HDAC2

2.94e-04114423.40.800.20
DomainHis_deacetylse

HDAC1 HDAC2

2.94e-0411442IPR000286
DomainSH3_9

RIMBP3 RIMBP3C RIMBP3B

8.20e-0478443PF14604
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

1.09e-0386443IPR011511
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

1.09e-0386443PF07653
DomainP-loop_NTPase

NAV2 KIF18A CHD9 DNA2 DNAH5 KIF26B MX2

3.42e-03848447IPR027417
DomainKinesin-like_fam

KIF18A KIF26B

4.61e-0343442IPR027640
DomainKINESIN_MOTOR_1

KIF18A KIF26B

4.82e-0344442PS00411
Domain-

KIF18A KIF26B

4.82e-03444423.40.850.10
DomainKinesin_motor_dom

KIF18A KIF26B

4.82e-0344442IPR001752
DomainKinesin

KIF18A KIF26B

4.82e-0344442PF00225
DomainKISc

KIF18A KIF26B

4.82e-0344442SM00129
DomainKINESIN_MOTOR_2

KIF18A KIF26B

4.82e-0344442PS50067
Domainp53-like_TF_DNA-bd

MGA NFAT5

6.93e-0353442IPR008967
DomainChannel_four-helix_dom

CACNA1D CACNA1S

7.97e-0357442IPR027359
Domain-

CACNA1D CACNA1S

7.97e-03574421.20.120.350
DomainFN3

RIMBP3 RIMBP3C RIMBP3B

1.15e-02199443PS50853
DomainFN3_dom

RIMBP3 RIMBP3C RIMBP3B

1.31e-02209443IPR003961
DomainSH3

RIMBP3 RIMBP3C RIMBP3B

1.43e-02216443PS50002
PathwayKEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES

MGA HDAC1 HDAC2

3.60e-0527343M47941
PathwayREACTOME_SIGNALING_BY_ALK

JAK3 HDAC1 HDAC2

4.98e-0530343M42517
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES

FOXO3 HDAC1 HDAC2

4.98e-0530343M27941
PathwayWP_HISTONE_MODIFICATIONS

HDAC1 HDAC2

5.62e-055342MM15874
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

CAMK2G HDAC1 HDAC2

6.06e-0532343M27900
PathwayPID_IL2_PI3K_PATHWAY

FOXO3 JAK3 EIF3A

7.29e-0534343M143
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1D CACNA1S

8.42e-056342M47762
PathwayREACTOME_P75NTR_NEGATIVELY_REGULATES_CELL_CYCLE_VIA_SC1

HDAC1 HDAC2

8.42e-056342M27072
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION

HDAC1 HDAC2

1.18e-047342M47673
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1D COL5A2 CACNA1S

1.38e-0442343M7169
PathwayWP_ENERGY_METABOLISM

FOXO3 CAMK2G HDAC1

2.06e-0448343M39590
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

HDAC1 HDAC2

3.06e-0411342M42523
PathwayKEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION

HDAC1 HDAC2

3.06e-0411342M47438
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

CACNA1D COL5A2 CACNA1S

4.61e-0463343M11187
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

CAMK2G HDAC1 HDAC2

4.61e-0463343M27862
PathwayBIOCARTA_PRC2_PATHWAY

HDAC1 HDAC2

5.05e-0414342M22025
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

CACNA1D CACNA1S

5.05e-0414342M47692
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

FOXO3 HDAC1 HDAC2

5.29e-0466343M27938
PathwayBIOCARTA_PITX2_PATHWAY

TRRAP HDAC1

6.63e-0416342M8516
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF18A KIF26B HDAC1 HDAC2

7.14e-04170344M941
PathwayBIOCARTA_MEF2D_PATHWAY

HDAC1 HDAC2

8.43e-0418342M5290
PathwayREACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS

HDAC1 HDAC2

8.43e-0418342M27901
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TRRAP HDAC1 HDAC2

9.28e-0480343M223
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

FOXO3 HDAC1 HDAC2

9.97e-0482343M2
PathwayWP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS

HDAC1 HDAC2

1.04e-0320342M48330
PathwayBIOCARTA_IL6_PATHWAY

SRF JAK3

1.15e-0321342M5489
PathwayBIOCARTA_IL6_PATHWAY

SRF JAK3

1.27e-0322342MM1415
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1D CACNA1S

1.38e-0323342M47666
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

SRF FOXO3

1.51e-0324342M27952
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CACNA1D CAMK2G

1.51e-0324342M47509
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

SRF FOXO3 CACNA1D COL5A2 CACNA1S CHD9 HNF1B SALL1 HDAC1 HDAC2

1.52e-0314323410M509
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

SRF JAK3 COL5A2 CYFIP1 HDAC1 HDAC2

1.53e-03532346M27870
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CACNA1D CAMK2G

1.64e-0325342M47510
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CACNA1D CAMK2G

1.64e-0325342M47511
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1D CACNA1S

1.64e-0325342M47948
PathwayBIOCARTA_CARM_ER_PATHWAY

HDAC1 HDAC2

1.77e-0326342M2499
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TRRAP HDAC1

1.77e-0326342MM14793
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CACNA1D CACNA1S CAMK2G

1.82e-03101343M1979
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

HDAC1 HDAC2

2.05e-0328342M6177
PathwayREACTOME_ADIPOGENESIS

CHD9 HDAC1 HDAC2

2.32e-03110343M48259
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

HDAC1 HDAC2

2.35e-0330342M27637
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_BROWN_AND_BEIGE_ADIPOCYTE_DIFFERENTIATION

HDAC1 HDAC2

2.51e-0331342M48258
PathwayWP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS

HDAC1 HDAC2

2.51e-0331342M39714
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

HDAC1 HDAC2

2.68e-0332342M39521
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF18A KIF26B HDAC1

2.70e-03116343MM15715
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

CYFIP1 CAMK2G

2.84e-0333342M39875
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

8.09e-09445319091768
Pubmed

ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.

SSBP2 TRRAP HDAC1 HDAC2

1.17e-082045416407974
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

2.02e-08545317855024
Pubmed

Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.

HNF1B SALL1 HDAC1 HDAC2

3.58e-082645429712641
Pubmed

Murine Sall1 represses transcription by recruiting a histone deacetylase complex.

SALL1 HDAC1 HDAC2

4.04e-08645311836251
Pubmed

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse.

FOXO3 SMCHD1 HDAC1

1.13e-07845315890782
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

SLX4IP KIF18A CHD9 SALL1 MGA LRIF1

4.18e-0722245637071664
Pubmed

The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.

EIF3A HDAC1 HDAC2

5.74e-071345312124384
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

MGA TRRAP LRIF1 HDAC1 HDAC2

5.79e-0712445520850016
Pubmed

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

SALL1 MYEF2 HDAC1 HDAC2

6.83e-075345421532573
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

7.29e-071445317662146
Pubmed

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.

EIF3A HDAC1 HDAC2

9.11e-07154539804427
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

CHD9 RNF168 MGA TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

1.02e-0660845836089195
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CRYBG3 SALL1 MGA CAMK2G HDAC1 HDAC2 KNL1

1.05e-0641845734709266
Pubmed

Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.

EIF3A HDAC1 HDAC2

1.12e-061645311102443
Pubmed

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.

FOXO3 HDAC1 HDAC2

1.36e-061745317322895
Pubmed

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.

EIF3A HDAC1 HDAC2

1.63e-06184539790534
Pubmed

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

EIF3A HDAC1 HDAC2

1.63e-061845310444591
Pubmed

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.

SSBP2 HDAC1 HDAC2

1.63e-061845319497860
Pubmed

CircFOXO3 promotes glioblastoma progression by acting as a competing endogenous RNA for NFAT5.

FOXO3 NFAT5

1.64e-06245231504797
Pubmed

The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle.

HDAC1 HDAC2

1.64e-06245235575026
Pubmed

Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis.

HDAC1 HDAC2

1.64e-06245223792463
Pubmed

Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.

HDAC1 HDAC2

1.64e-06245219531758
Pubmed

Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro.

HDAC1 HDAC2

1.64e-06245231222845
Pubmed

The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.

HDAC1 HDAC2

1.64e-06245224525021
Pubmed

HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.

HDAC1 HDAC2

1.64e-06245211287668
Pubmed

Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development.

HDAC1 HDAC2

1.64e-06245231533525
Pubmed

Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown.

HDAC1 HDAC2

1.64e-06245234890513
Pubmed

Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts.

HDAC1 HDAC2

1.64e-06245232366868
Pubmed

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

HDAC1 HDAC2

1.64e-06245221423190
Pubmed

Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.

HDAC1 HDAC2

1.64e-06245224335310
Pubmed

Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway.

HDAC1 HDAC2

1.64e-06245238523117
Pubmed

Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC.

HDAC1 HDAC2

1.64e-06245218408217
Pubmed

HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.

HDAC1 HDAC2

1.64e-06245228579617
Pubmed

HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition.

HDAC1 HDAC2

1.64e-06245229641990
Pubmed

HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.

HDAC1 HDAC2

1.64e-06245224040068
Pubmed

Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.

HDAC1 HDAC2

1.64e-06245226174178
Pubmed

[Regulatory effect of ginsenoside Rh2 on HDAC1/2 activity and cyclin in human erythroleukemia K562 cells].

HDAC1 HDAC2

1.64e-06245225270209
Pubmed

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

HDAC1 HDAC2

1.64e-06245222156779
Pubmed

Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer.

HDAC1 HDAC2

1.64e-06245223251689
Pubmed

Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity.

HDAC1 HDAC2

1.64e-06245232934238
Pubmed

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.

HDAC1 HDAC2

1.64e-06245220802485
Pubmed

Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.

HDAC1 HDAC2

1.64e-06245231799598
Pubmed

The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31.

HDAC1 HDAC2

1.64e-06245215016876
Pubmed

Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions.

HDAC1 HDAC2

1.64e-06245211919195
Pubmed

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia.

HDAC1 HDAC2

1.64e-06245221292776
Pubmed

Genetic dissection of histone deacetylase requirement in tumor cells.

HDAC1 HDAC2

1.64e-06245219416910
Pubmed

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

HDAC1 HDAC2

1.64e-06245223287868
Pubmed

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells.

HDAC1 HDAC2

1.64e-06245231071955
Pubmed

Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers.

HDAC1 HDAC2

1.64e-06245225942572
Pubmed

Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function.

HDAC1 HDAC2

1.64e-06245219553468
Pubmed

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

HDAC1 HDAC2

1.64e-06245224449838
Pubmed

HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.

HDAC1 HDAC2

1.64e-06245220398369
Pubmed

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice.

HDAC1 HDAC2

1.64e-06245222307625
Pubmed

Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease.

HDAC1 HDAC2

1.64e-06245226116233
Pubmed

Dynamic distribution of HDAC1 and HDAC2 during mitosis: association with F-actin.

HDAC1 HDAC2

1.64e-06245223280436
Pubmed

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.

HDAC1 HDAC2

1.64e-06245225688158
Pubmed

Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse.

HDAC1 HDAC2

1.64e-06245223516383
Pubmed

Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection.

HDAC1 HDAC2

1.64e-06245219740981
Pubmed

NuRD and SIN3 histone deacetylase complexes in development.

HDAC1 HDAC2

1.64e-06245210904264
Pubmed

HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.

HDAC1 HDAC2

1.64e-06245225648995
Pubmed

SMCHD1 and LRIF1 converge at the FSHD-associated D4Z4 repeat and LRIF1 promoter yet display different modes of action.

LRIF1 SMCHD1

1.64e-06245237380887
Pubmed

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.

HDAC1 HDAC2

1.64e-06245217639084
Pubmed

Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly.

HDAC1 HDAC2

1.64e-06245230209338
Pubmed

HDAC1 and HDAC2 are differentially expressed in endometriosis.

HDAC1 HDAC2

1.64e-06245222344732
Pubmed

[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].

CACNA1D CACNA1S

1.64e-06245221789999
Pubmed

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome.

LRIF1 SMCHD1

1.64e-06245226391951
Pubmed

HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.

HDAC1 HDAC2

1.64e-06245230926862
Pubmed

Trans-regulation of histone deacetylase activities through acetylation.

HDAC1 HDAC2

1.64e-06245219822520
Pubmed

Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer.

HDAC1 HDAC2

1.64e-06245231692265
Pubmed

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.

CACNA1D CACNA1S

1.64e-06245228978442
Pubmed

HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death.

FOXO3 HDAC2

1.64e-06245225609639
Pubmed

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.

HDAC1 HDAC2

1.64e-06245215297431
Pubmed

Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.

HDAC1 HDAC2

1.64e-06245224958871
Pubmed

Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.

HDAC1 HDAC2

1.64e-06245220585871
Pubmed

Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.

HDAC1 HDAC2

1.64e-06245226129908
Pubmed

Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation.

HDAC1 HDAC2

1.64e-06245219412887
Pubmed

A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes.

HDAC1 HDAC2

1.64e-06245219561124
Pubmed

HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population.

HDAC1 HDAC2

1.64e-06245226352599
Pubmed

Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP modulates gene expression and apoptosis.

FOXO3 TRRAP

1.64e-06245235151693
Pubmed

Leucine zipper domain is required for Kaposi sarcoma-associated herpesvirus (KSHV) K-bZIP protein to interact with histone deacetylase and is important for KSHV replication.

HDAC1 HDAC2

1.64e-06245222416134
Pubmed

Histone deacetylase 1 and 2 in mesenchymal tumors.

HDAC1 HDAC2

1.64e-06245222037263
Pubmed

Loss of histone deacetylase 2 improves working memory and accelerates extinction learning.

HDAC1 HDAC2

1.64e-06245223575838
Pubmed

Podocyte histone deacetylase activity regulates murine and human glomerular diseases.

HDAC1 HDAC2

1.64e-06245230776024
Pubmed

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

HDAC1 HDAC2

1.64e-06245221270520
Pubmed

HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer.

HDAC1 HDAC2

1.64e-06245230669676
Pubmed

JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice.

HDAC1 HDAC2

1.64e-06245233498747
Pubmed

Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy.

HDAC1 HDAC2

1.64e-06245221725353
Pubmed

Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells.

HDAC1 HDAC2

1.64e-06245236346011
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

SALL1 MGA TRRAP HDAC1 HDAC2

2.51e-0616745520362541
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

COL5A2 KIF18A RIMBP3C MBD5 MGA KIF26B LRIF1 MYEF2

2.57e-0668945836543142
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

MBD5 MGA LRIF1 SMCHD1 HDAC1 HDAC2 KNL1

3.22e-0649545727705803
Pubmed

MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.

TRRAP HDAC1 HDAC2

3.52e-062345320332121
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

MGA TRRAP LRIF1 HDAC1 HDAC2 KNL1

4.85e-0633945630415952
Pubmed

Loss of histone deacetylases 1 and 2 in hepatocytes impairs murine liver regeneration through Ki67 depletion.

HDAC1 HDAC2

4.91e-06345223744762
Pubmed

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.

HDAC1 HDAC2

4.91e-06345230279482
Pubmed

HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis.

HDAC1 HDAC2

4.91e-06345238679196
Pubmed

Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis.

HDAC1 HDAC2

4.91e-06345224763403
Pubmed

Mutual Balance of Histone Deacetylases 1 and 2 and the Acetyl Reader ATAD2 Regulates the Level of Acetylation of Histone H4 on Nascent Chromatin of Human Cells.

HDAC1 HDAC2

4.91e-06345232015101
Pubmed

Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration.

HDAC1 HDAC2

4.91e-06345228139683
InteractionFOXG1 interactions

SRF FOXO3 SALL1 HDAC1 HDAC2

1.97e-0695445int:FOXG1
InteractionTEAD1 interactions

SRF SSBP2 SALL1 MGA TRRAP SMCHD1

2.18e-06176446int:TEAD1
InteractionTFCP2L1 interactions

SALL1 MGA TRRAP HDAC1 HDAC2

2.41e-0699445int:TFCP2L1
InteractionDACT2 interactions

TRRAP CAMK2G SMCHD1

5.33e-0616443int:DACT2
InteractionRBL1 interactions

FOXO3 MGA TRRAP HDAC1 HDAC2

6.47e-06121445int:RBL1
InteractionPHF21A interactions

CRYBG3 SALL1 MGA CAMK2G HDAC1 HDAC2 KNL1

8.68e-06343447int:PHF21A
InteractionNCOR1 interactions

KIF18A HNF1B EIF3A MGA TRRAP HDAC1 HDAC2

1.25e-05363447int:NCOR1
InteractionEPB41L3 interactions

CHD9 EIF3A CYFIP1 SMCHD1 HDAC1 CNTNAP2

2.63e-05272446int:EPB41L3
InteractionLHX4 interactions

HNF1B SSBP2 CYFIP1 MGA TRRAP

2.99e-05166445int:LHX4
InteractionSUMO2 interactions

SLX4IP HNF1B IGBP1 SALL1 RNF168 SMCHD1 HDAC1 HDAC2

3.64e-05591448int:SUMO2
InteractionNR3C1 interactions

CHD9 CYFIP1 SALL1 LRIF1 CAMK2G SMCHD1 MYEF2 HDAC1 HDAC2 KNL1

3.67e-059744410int:NR3C1
InteractionC22orf31 interactions

HDAC1 HDAC2

4.64e-055442int:C22orf31
InteractionTAL1 interactions

SSBP2 TRRAP HDAC1 HDAC2

5.01e-0593444int:TAL1
InteractionYY1 interactions

HNF1B MGA TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

5.24e-05454447int:YY1
InteractionBRMS1 interactions

HNF1B LRIF1 HDAC1 HDAC2

5.67e-0596444int:BRMS1
InteractionBRCA1 interactions

FOXO3 SLX4IP UBE2J1 KIF18A CHD9 EIF3A RNF168 SMCHD1 HDAC1 HDAC2 KNL1

5.70e-0512494411int:BRCA1
InteractionMIER2 interactions

MGA HDAC1 HDAC2

7.16e-0537443int:MIER2
InteractionZEB1 interactions

SRF HNF1B MGA HDAC1 HDAC2

7.26e-05200445int:ZEB1
InteractionING1 interactions

HNF1B TRRAP HDAC1 HDAC2

7.46e-05103444int:ING1
InteractionH3C3 interactions

RNF168 MGA TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

9.02e-05495447int:H3C3
InteractionCIC interactions

HNF1B EIF3A SALL1 MGA NFAT5 SMCHD1 HDAC1 HDAC2

9.07e-05673448int:CIC
InteractionPARP1 interactions

SRF SLX4IP HNF1B RNF168 MBD5 MGA TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

9.13e-0513164411int:PARP1
InteractionYAP1 interactions

HNF1B IGBP1 EIF3A CYFIP1 MGA NFAT5 TRRAP SMCHD1 HDAC1 HDAC2

9.83e-0510954410int:YAP1
InteractionPPIA interactions

CACNA1D IGBP1 CYFIP1 CRYBG3 TRRAP HDAC1 HDAC2 KNL1 CNTNAP2

1.06e-04888449int:PPIA
InteractionELF4 interactions

MGA TRRAP LRIF1 SMCHD1

1.15e-04115444int:ELF4
InteractionH3C1 interactions

NAV2 HNF1B MBD5 MGA TRRAP LRIF1 SMCHD1 HDAC1 HDAC2

1.18e-04901449int:H3C1
InteractionZHX3 interactions

SRF HDAC1 HDAC2

1.21e-0444443int:ZHX3
InteractionRARA interactions

SRF EIF3A LRIF1 HDAC1 HDAC2

1.21e-04223445int:RARA
InteractionMXD1 interactions

MGA HDAC1 HDAC2

1.29e-0445443int:MXD1
InteractionSNAI3 interactions

HDAC1 HDAC2

1.29e-048442int:SNAI3
InteractionNFIX interactions

SRF SALL1 MGA TRRAP HDAC1

1.32e-04227445int:NFIX
InteractionRBBP8 interactions

DNA2 TRRAP HDAC1 HDAC2

1.44e-04122444int:RBBP8
InteractionCDC20 interactions

KIF18A TRRAP HDAC1 HDAC2 KNL1

1.52e-04234445int:CDC20
InteractionPML interactions

SRF SLX4IP KIF18A IGBP1 EIF3A SMCHD1 HDAC1 HDAC2 KNL1

1.54e-04933449int:PML
InteractionRFPL4B interactions

SALL1 MGA LRIF1

1.57e-0448443int:RFPL4B
InteractionSLFN11 interactions

EIF3A RNF168 DNA2 TRRAP HDAC1 HDAC2

1.57e-04376446int:SLFN11
InteractionELF1 interactions

MGA TRRAP LRIF1 SMCHD1

1.63e-04126444int:ELF1
InteractionFOXK1 interactions

SRF FOXO3 MBD5 HDAC1 HDAC2

1.64e-04238445int:FOXK1
InteractionSMAD7 interactions

SRF COL5A2 HDAC1 HDAC2

1.68e-04127444int:SMAD7
InteractionMGA interactions

HNF1B MGA TRRAP LRIF1 HDAC1

1.71e-04240445int:MGA
InteractionMYH9 interactions

CHD9 SSBP2 EIF3A CYFIP1 TRRAP DNAH5 HDAC1 HDAC2

1.98e-04754448int:MYH9
InteractionSLX4 interactions

SLX4IP KIF18A CHD9 SALL1 MGA LRIF1 SMCHD1

2.20e-04572447int:SLX4
InteractionADNP2 interactions

SRF LRIF1 MYEF2

2.23e-0454443int:ADNP2
InteractionBUB1 interactions

DNA2 KIF26B HDAC1 KNL1

2.25e-04137444int:BUB1
InteractionKDM5C interactions

MGA TRRAP HDAC1 HDAC2

2.37e-04139444int:KDM5C
InteractionAR interactions

SSBP2 CYFIP1 MGA TRRAP SMCHD1 MYEF2 HDAC1 HDAC2 KNL1

2.44e-04992449int:AR
InteractionESRRB interactions

SALL1 MGA TRRAP HDAC1 HDAC2

2.57e-04262445int:ESRRB
InteractionMDC1 interactions

SLX4IP RNF168 MGA TRRAP SMCHD1 KNL1

2.64e-04414446int:MDC1
InteractionTRPS1 interactions

SRF HNF1B HDAC1 HDAC2

2.65e-04143444int:TRPS1
InteractionNCOR2 interactions

SRF HNF1B TRRAP HDAC1 HDAC2

2.66e-04264445int:NCOR2
InteractionFBXO38 interactions

KIF18A TRRAP LRIF1 KNL1

2.79e-04145444int:FBXO38
InteractionCREBBP interactions

SRF FOXO3 HNF1B MGA TRRAP HDAC1 HDAC2

2.92e-04599447int:CREBBP
InteractionOVOL1 interactions

HDAC1 HDAC2

3.03e-0412442int:OVOL1
InteractionMRTFA interactions

SRF TRRAP HDAC1

3.05e-0460443int:MRTFA
InteractionCARD8 interactions

MGA TRRAP LRIF1

3.05e-0460443int:CARD8
InteractionCAMK2A interactions

SRF SSBP2 CYFIP1 CAMK2G SMCHD1

3.43e-04279445int:CAMK2A
InteractionSOX6 interactions

HNF1B SMCHD1 HDAC1 HDAC2

3.78e-04157444int:SOX6
InteractionTCF7L2 interactions

SRF HNF1B TRRAP HDAC1 HDAC2

3.78e-04285445int:TCF7L2
InteractionH3-4 interactions

MGA TRRAP DNAH5 LRIF1 HDAC1 HDAC2

4.03e-04448446int:H3-4
InteractionARID5B interactions

HNF1B HDAC1 HDAC2

4.22e-0467443int:ARID5B
InteractionING2 interactions

HNF1B HDAC1 HDAC2

4.41e-0468443int:ING2
InteractionMBD3 interactions

IGBP1 SALL1 TRRAP HDAC1 HDAC2

4.42e-04295445int:MBD3
InteractionCUL4A interactions

NAV2 UBE2J1 EIF3A CYFIP1 DNA2 CAMK2G HDAC1 HDAC2

4.59e-04854448int:CUL4A
InteractionZHX2 interactions

SRF HDAC1 HDAC2

4.60e-0469443int:ZHX2
InteractionMKI67 interactions

NAV2 KIF18A RNF168 MGA TRRAP HDAC1 HDAC2

4.68e-04648447int:MKI67
InteractionGPR158 interactions

GPR158 CNTNAP2

4.80e-0415442int:GPR158
InteractionPPP2R2A interactions

CACNA1S IGBP1 EIF3A HDAC1 HDAC2

4.85e-04301445int:PPP2R2A
InteractionH2AC1 interactions

TRRAP HDAC1 HDAC2

5.00e-0471443int:H2AC1
InteractionRNF2 interactions

UBE2J1 EIF3A MGA TRRAP SMCHD1 MYEF2 HDAC1 HDAC2

5.04e-04866448int:RNF2
InteractionTWIST1 interactions

CHD9 MGA MYEF2 HDAC2

5.10e-04170444int:TWIST1
InteractionPCGF6 interactions

MGA LRIF1 HDAC1 HDAC2

5.21e-04171444int:PCGF6
InteractionPIAS4 interactions

MGA LRIF1 HDAC1 HDAC2

5.45e-04173444int:PIAS4
InteractionHOPX interactions

SRF HDAC2

5.48e-0416442int:HOPX
InteractionNANOG interactions

SALL1 MGA TRRAP MYEF2 HDAC1 HDAC2

5.86e-04481446int:NANOG
InteractionSNAPC4 interactions

MTFR2 CAMK2G KNL1

6.11e-0476443int:SNAPC4
InteractionLRRC24 interactions

CYFIP1 TRRAP

6.21e-0417442int:LRRC24
InteractionSYN1 interactions

CYFIP1 CAMK2G CNTNAP2

6.35e-0477443int:SYN1
InteractionCHAF1A interactions

EIF3A CYFIP1 LRIF1 HDAC1 HDAC2

6.58e-04322445int:CHAF1A
InteractionCBFA2T3 interactions

SSBP2 HDAC1 HDAC2

6.59e-0478443int:CBFA2T3
InteractionRCOR1 interactions

HNF1B SALL1 MGA HDAC1 HDAC2 KNL1

6.74e-04494446int:RCOR1
InteractionEP400 interactions

HNF1B TRRAP HDAC1 HDAC2

6.86e-04184444int:EP400
InteractionE2F6 interactions

MGA LRIF1 HDAC1 HDAC2

7.00e-04185444int:E2F6
InteractionHIVEP1 interactions

SRF HNF1B CAMK2G HDAC1

7.15e-04186444int:HIVEP1
InteractionMCCC1 interactions

SSBP2 SALL1 HDAC1 HDAC2

7.29e-04187444int:MCCC1
InteractionEPC1 interactions

SRF HNF1B TRRAP

7.36e-0481443int:EPC1
InteractionPRNP interactions

COL5A2 KIF18A RIMBP3C MBD5 MGA KIF26B LRIF1 CAMK2G MYEF2

7.57e-041158449int:PRNP
InteractionHNF1B interactions

HNF1B MGA TRRAP HDAC1

7.74e-04190444int:HNF1B
InteractionCABIN1 interactions

HNF1B HDAC1 HDAC2

7.90e-0483443int:CABIN1
InteractionSALL4 interactions

SALL1 HDAC1 HDAC2

7.90e-0483443int:SALL4
InteractionNR2C1 interactions

HNF1B HDAC1 HDAC2

8.18e-0484443int:NR2C1
InteractionPRDM1 interactions

HNF1B HDAC1 HDAC2

8.18e-0484443int:PRDM1
InteractionPOLH interactions

HNF1B HDAC1 KNL1

8.18e-0484443int:POLH
InteractionMYOD1 interactions

SRF MGA TRRAP HDAC1

8.36e-04194444int:MYOD1
InteractionKDM1A interactions

CRYBG3 RNF168 MGA TRRAP CAMK2G HDAC1 HDAC2 KNL1

8.69e-04941448int:KDM1A
InteractionBPTF interactions

SRF HNF1B HDAC1 HDAC2

8.86e-04197444int:BPTF
InteractionJMJD1C interactions

RNF168 HDAC1 HDAC2

9.36e-0488443int:JMJD1C
InteractionUHRF2 interactions

JAK3 MGA SMCHD1 HDAC1

9.37e-04200444int:UHRF2
InteractionZNF488 interactions

RIMBP3 CAMK2G

9.53e-0421442int:ZNF488
InteractionHOXA11 interactions

HDAC1 HDAC2

9.53e-0421442int:HOXA11
InteractionPOLR1E interactions

MGA TRRAP LRIF1 CAMK2G HDAC1

9.56e-04350445int:POLR1E
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B

1.81e-0411145322q11.21
Cytoband15q14

MGA KNL1

1.07e-034945215q14
Cytoband6q21

FOXO3 HDAC2

4.04e-03964526q21
CytobandEnsembl 112 genes in cytogenetic band chr16q12

CHD9 SALL1

4.63e-03103452chr16q12
CytobandEnsembl 112 genes in cytogenetic band chr6q21

FOXO3 HDAC2

6.33e-03121452chr6q21
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

1.49e-054292989
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

8.88e-0592921306
GeneFamilyPHD finger proteins|NuRD complex

HDAC1 HDAC2

1.62e-04122921305
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

1.62e-04122921243
GeneFamilyCalcium voltage-gated channel subunits

CACNA1D CACNA1S

7.88e-0426292253
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF18A KIF26B

2.46e-0346292622
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KIF18A KNL1

3.39e-02181292694
CoexpressionGSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP

SSBP2 ART4 SMCHD1 MX2 HDAC2

1.01e-05172445M2945
CoexpressionCHEN_HOXA5_TARGETS_9HR_UP

FOXO3 KIF18A CHD9 LRIF1 SMCHD1

3.53e-05223445M17621
CoexpressionIKEDA_MIR30_TARGETS_UP

UBE2J1 CHD9 SSBP2 NFAT5

4.31e-05116444M2379
CoexpressionIKEDA_MIR30_TARGETS_UP

UBE2J1 CHD9 SSBP2 NFAT5

4.46e-05117444MM931
CoexpressionVANHARANTA_UTERINE_FIBROID_UP

NAV2 COL5A2 ART4

5.57e-0544443M18274
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

FOXO3 COL5A2 CHD9 SSBP2 EIF3A CRYBG3 TRRAP SMCHD1

7.82e-05856448M4500
CoexpressionAtlasalpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3

KIF18A SSBP2 MTFR2 DNA2 MROH2A MYEF2 KNL1

1.89e-05398457GSM399397_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

NAV2 CHD9 SSBP2 EIF3A MGA NFAT5 HDAC2

2.26e-05409457gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

KIF18A CHD9 EIF3A MTFR2 SALL1 RNF168 MBD5 DNA2 LRIF1 SMCHD1 KNL1 CNTNAP2

3.62e-0514594512facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

KIF18A CHD9 EIF3A MTFR2 RNF168 MBD5 DNA2 LRIF1 SMCHD1 KNL1 CNTNAP2

4.70e-0512574511facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200

KIF18A SSBP2 NFAT5

8.32e-0540453gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

UBE2J1 KIF18A EIF3A SALL1 RNF168 DNA2 KIF26B MYEF2 CNTNAP2

1.85e-04983459Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500

NAV2 CHD9 SSBP2 EIF3A MGA HDAC2

2.04e-04406456gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

NAV2 CHD9 SSBP2 EIF3A MGA NFAT5 HDAC2 KNL1

2.25e-04790458gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000

KIF18A HNF1B SSBP2 SALL1 RNF168 DNA2 NFAT5 CNTNAP2

2.47e-04801458gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

NAV2 CHD9 SSBP2 EIF3A MGA NFAT5 SMCHD1 HDAC2

2.54e-04804458gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000

KIF18A SSBP2 NFAT5 KNL1

2.57e-04146454gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000

CACNA1D KIF18A SSBP2 SALL1 RNF168 NFAT5 KIF26B KNL1

2.64e-04809458gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#4_top-relative-expression-ranked_500

EIF3A MGA NFAT5

2.80e-0460453gudmap_developingGonad_e12.5_ovary_k4_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

UBE2J1 EIF3A RNF168 MGA KIF26B KNL1

2.85e-04432456Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

UBE2J1 KIF18A CHD9 EIF3A MTFR2 DNA2 LRIF1 KNL1 CNTNAP2

3.24e-041060459facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLX4IP KIF18A MTFR2 MX2 KNL1

9.31e-0717645590f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAV2 KIF18A MTFR2 DNA2 KNL1

1.43e-061924550a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

KIF18A MTFR2 MROH2A KNL1

3.32e-061014540b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellControl-T/NK_proliferative|World / Disease group and Cell class

KIF18A MTFR2 MYEF2 KNL1

2.54e-05169454fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MTFR2 DNA2 KNL1

2.54e-05169454b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRF NAV2 COL5A2 ART4

2.60e-05170454fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SRF NAV2 COL5A2 ART4

2.60e-0517045403044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_DZ|tumor_Lung / Location, Cell class and cell subclass

UBE2J1 SSBP2 MTFR2 KNL1

3.11e-05178454c57f92e57548638f1627dc7d313137f406dbecff
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

KIF18A MTFR2 MYEF2 KNL1

3.46e-0518345409c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

CHD9 NFAT5 SMCHD1 MX2

3.46e-051834548f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

KIF18A MTFR2 DNA2 KNL1

3.46e-05183454df8568751205313d149939ea2683097e3652a60b
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|COVID-19 / Disease (COVID-19 only), tissue and cell type

JAK3 UBE2J1 KIF18A KNL1

3.85e-05188454599195338070ac6b79bd114609d9e10cac4f1df4
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXO3 COL5A2 SALL1 DNAH5

3.85e-05188454997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A MTFR2 DNA2 KNL1

3.93e-05189454d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 JAK3 ART4

4.01e-051904541121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 JAK3 ART4

4.01e-05190454048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CACNA1D COL5A2 SSBP2 CNTNAP2

4.01e-051904547986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-Cycling_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KIF18A MTFR2 DNA2 KNL1

4.09e-051914545d4fed25bd318472a17228b12ade4c331865bda5
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

FOXO3 COL5A2 CHD9 SSBP2

4.09e-05191454d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAV2 KIF18A DNA2 KNL1

4.18e-0519245427723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

NAV2 CACNA1D COL5A2 KIF26B

4.18e-0519245462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_DC1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GRAMD2A DNA2 MYEF2 KNL1

4.26e-0519345442775588e788c330aade07e54b208f1c2eea3ab3
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

NAV2 KIF18A DNA2 KNL1

4.26e-0519345433d409d6ed1c606337248587ad997ac5f67f081d
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A MTFR2 KNL1 CNTNAP2

4.26e-05193454b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 KIF18A MTFR2 MYEF2

4.35e-0519445406b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Pro-B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIF18A SSBP2 MTFR2 KNL1

4.35e-0519445458d7c56d2b9c893b62da2334428d677e3451fe07
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

NAV2 FOXO3 COL5A2 CHD9

4.35e-05194454234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

NAV2 CACNA1D COL5A2 KIF26B

4.44e-05195454603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

FOXO3 COL5A2 CHD9 SSBP2

4.44e-05195454ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAV2 MTFR2 ART4 KNL1

4.53e-05196454eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL5A2 KIF18A KIF26B KNL1

4.53e-05196454ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF18A MTFR2 SALL1 KNL1

4.53e-051964545905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

COL5A2 KIF18A KIF26B KNL1

4.53e-051964542ce8a787f2731faa913d20342d73041d59468f27
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXO3 COL5A2 CRYBG3 SALL1

4.53e-051964542ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 COL5A2 ART4

4.62e-0519745485a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 COL5A2 ART4

4.62e-051974549b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 COL5A2 ART4

4.62e-05197454e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV2 KIF18A MYEF2 KNL1

4.71e-05198454c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

NAV2 CACNA1D COL5A2 KIF26B

4.71e-05198454df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

NAV2 CACNA1D COL5A2 KIF26B

4.71e-051984543ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 COL5A2 ART4

4.71e-05198454a860246bcea847249a78fd2e86ed8e04371060db
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 KIF18A MYEF2 KNL1

4.80e-05199454c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell3'-GW_trimst-1.5|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A2 CHD9 SSBP2 HDAC2

4.80e-051994548e69d718ed5b05b08550973c33c92f0c6bfccc68
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAV2 KIF18A MYEF2 KNL1

4.80e-0519945498575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAV2 KIF18A MTFR2 KNL1

4.80e-05199454be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellBL-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A MTFR2 DNA2 KNL1

4.89e-0520045404d95a9102248e98eed069840ea6d3d23a243fd5
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DNA2 HDAC2 KNL1

2.66e-041244531483be8700eca7e2c288784a290d945d4022b17f
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRAMD2A ART4 KNL1

2.79e-041264536cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRAMD2A ART4 KNL1

2.79e-0412645369b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A MTFR2 KNL1

3.13e-04131453f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

CACNA1D CHD9 NFAT5

3.42e-04135453ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTFR2 DNA2 KNL1

3.96e-04142453be63c48794a227ea55978524c0f5935342fc455e
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

NAV2 CACNA1D COL5A2

4.47e-0414845381a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A MTFR2 KNL1

4.47e-04148453b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A MTFR2 KNL1

4.47e-041484532a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSBP2 MROH2A KNL1

4.65e-04150453973252f4de9a1194aea9f3cb0e1f113643f16c91
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAK3 SMCHD1 MX2

4.74e-04151453b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UBE2J1 COL5A2

4.76e-0432452ba89b22a5ce8ee9f3099b1fa84721724b94c7759
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UBE2J1 COL5A2

4.76e-043245258b212d4f2955f06a195df0f79ad95a8ff145b83
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

JAK3 MX2 KNL1

5.12e-041554537e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HNF1B SALL1 CNTNAP2

5.12e-041554533b8def9e8f66511736ea37f259511f7c8b7743af
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HNF1B SALL1 CNTNAP2

5.12e-0415545399e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLX4IP GRAMD2A CYFIP1

5.21e-041564535b2781d38a83b4b0f8a53cf321ce5db3a07d0818
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLX4IP GRAMD2A CYFIP1

5.21e-04156453e0aef6104be16b12304b8e30358f444c1660e92f
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTFR2 DNA2 SMCHD1

5.31e-04157453eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL5A2 DNAH5 GPR158

5.41e-04158453c8af8964a140acb2987e3b4906d72c546108d229
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

GRAMD2A CRYBG3 ART4

5.61e-04160453731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 MROH2A CNTNAP2

5.61e-04160453c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

GRAMD2A CRYBG3 ART4

5.61e-04160453cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 MROH2A CNTNAP2

5.61e-0416045325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMBP3 MTFR2 MROH2A

5.61e-04160453f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MTFR2 KNL1

6.14e-04165453eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DNA2 KNL1

6.14e-0416545388681101d7cf60b99b8ace5d8c0944323b937306
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLX4IP CACNA1S KIF26B

6.14e-04165453c39f0479955c4e23921f7a450d3bc251a002200f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MTFR2 KNL1

6.25e-041664532642544070564debe2deb2938d2c33997bf5ef02
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

KIF18A MTFR2 KNL1

6.25e-04166453c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DNA2 KNL1

6.36e-0416745350c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF18A MTFR2 KNL1

6.36e-041674539280558baddea51aae47f3383d895a9b0c6749a4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A DNA2 KNL1

6.47e-04168453d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH5 MROH2A CNTNAP2

6.58e-0416945312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HNF1B SALL1 CNTNAP2

6.69e-0417045314aa86a4f526ed6986afcb28c49225522055550c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MTFR2 SALL1 KNL1

6.69e-0417045373601c873b177d5d134618d8e228c51381119f7d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SLX4IP SSBP2 TRRAP

6.92e-04172453da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF18A DNA2 KNL1

6.92e-041724536fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MTFR2 KNL1

7.04e-04173453a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A MYEF2 KNL1

7.16e-04174453b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A MYEF2 KNL1

7.16e-0417445394575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A MYEF2 KNL1

7.16e-0417445340c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D GPR158 CNTNAP2

7.16e-04174453f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 ART4

7.28e-04175453f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 FOXO3 ART4

7.28e-04175453910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellClub-club-15|World / Class top

HNF1B MYEF2 KNL1

7.28e-04175453ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MTFR2 KNL1

7.28e-04175453876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

MTFR2 KNL1 CNTNAP2

7.28e-0417545374800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HNF1B SALL1 CNTNAP2

7.40e-0417645305ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTFR2 SMCHD1 KNL1

7.40e-041764539e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D SSBP2 MBD5

7.52e-04177453b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D COL5A2 KIF26B

7.52e-04177453cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2J1 CACNA1S MROH2A

7.52e-0417745341cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

KIF18A MTFR2 KNL1

7.52e-0417745305c57578142a6662f18b294d5cc11e6efd6b0f8e
DrugDehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A

JAK3 CACNA1D COL5A2 MX2 CNTNAP2

3.02e-051974255681_UP
DrugCatechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

UBE2J1 CHD9 NFAT5 CAMK2G SMCHD1

3.10e-051984254837_DN
DrugNilvadipine

CACNA1D CACNA1S

3.31e-055422DB06712
DrugNisoldipine

CACNA1D CACNA1S

3.31e-055422DB00401
DrugVorinostat

HDAC1 HDAC2

3.31e-055422DB02546
DrugAC1L9FY1

NFAT5 TRRAP HDAC1 HDAC2

3.59e-05101424CID000444218
Diseaseautism spectrum disorder (is_implicated_in)

CYFIP1 MBD5 CNTNAP2

1.09e-0616383DOID:0060041 (is_implicated_in)
Diseasetemporal lobe epilepsy (is_marker_for)

FOXO3 CYFIP1 HDAC2

2.21e-0620383DOID:3328 (is_marker_for)
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1D CACNA1S

9.67e-064382DOID:0060173 (implicated_via_orthology)
Diseasesusceptibility to bacterial meningitis measurement

CACNA1D NFAT5 DNAH5

4.17e-0552383EFO_0008411
Diseasealopecia areata (is_marker_for)

HDAC1 HDAC2

7.22e-0510382DOID:986 (is_marker_for)
Diseasethalamus volume

NAV2 FOXO3 NFAT5

1.81e-0485383EFO_0006935
Diseasewaist circumference

NAV2 FOXO3 NFAT5 DNAH5 CNTNAP2

2.15e-04429385EFO_0004342
Diseasevisceral adipose tissue measurement

FOXO3 KIF18A SSBP2 NFAT5 GPR158

3.63e-04481385EFO_0004765
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

FOXO3 CAMK2G MROH2A CNTNAP2

8.21e-04328384EFO_0008377, EFO_0008378
DiseaseChronic Obstructive Airway Disease

FOXO3 HDAC2

8.31e-0433382C0024117
DiseaseChronic Airflow Obstruction

FOXO3 HDAC2

8.31e-0433382C1527303
DiseaseFEV/FEC ratio

NAV2 FOXO3 CACNA1D MGA DNAH5 CAMK2G CNTNAP2

8.65e-041228387EFO_0004713
Diseaseacute lymphoblastic leukemia (is_marker_for)

HDAC1 HDAC2

8.83e-0434382DOID:9952 (is_marker_for)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1D CACNA1S

9.90e-0436382DOID:11723 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

NAV2 FOXO3 CHD9 HNF1B SALL1 CAMK2G

1.03e-03914386EFO_0004532

Protein segments in the cluster

PeptideGeneStartEntry
SMIVNSHKPQNNLDS

CRYBG3

1071

Q68DQ2
PMQLHLQNVTATSAN

RIMBP3B

996

A6NNM3
PMQLHLQNVTATSAN

RIMBP3C

996

A6NJZ7
QPQSQYQLSQMTFHK

JAK3

501

P52333
SMFLANHNKITQSLQ

CYFIP1

211

Q7L576
NPHMNQSSNYLKQSK

LRIF1

456

Q5T3J3
SQHINSNMPQSLKVG

MGA

1356

Q8IWI9
FKLHISPSNMTNQNT

HDAC1

341

Q13547
HATNFLNVMLQSNKS

GPR158

131

Q5T848
NKNRTQHPTDMNATS

KIF18A

211

Q8NI77
HQAKVSLQMATSPSN

KIF26B

286

Q2KJY2
LPKTMNNSAENHTAN

IGBP1

126

P78318
NTLLSAPIHTQMQQK

KNL1

136

Q8NG31
DNQPQVNLFSSTKSM

NFAT5

1016

O94916
ISMQQFSQTSNPSAH

CHD9

226

Q3L8U1
TAINLNNPESQSMHL

EIF3A

216

Q14152
QVNVIQSHTAPMSSK

CACNA1S

141

Q13698
DHQSPNTAITQMTFL

COL5A2

1376

P05997
QLHFTDPSMNSSVLQ

MBD5

736

Q9P267
FLNQMNNSSHSVLQP

CNTNAP2

501

Q9UHC6
DFKLHISPSNMTNQN

HDAC2

341

Q92769
QQMHRKTASLNSPVS

GRAMD2A

16

Q8IUY3
HKNTSTDFPQMQLSL

DNA2

226

P51530
MQALSPSNSTQEFHK

SALL1

926

Q9NSC2
ASFVKNQTQHLMGNS

IZUMO2

86

Q6UXV1
PTSTNANLNNANMSK

CACNA1D

1751

Q01668
SSVHLMPQSNNKNSL

CAMK2G

336

Q13555
SNSASNMKQNSLPIF

DNAH5

996

Q8TE73
NKAPAQHQYSSQNLM

MROH2A

356

A6NES4
NQSHLSQHLNKGTPM

HNF1B

146

P35680
GSAKHQQQSPVSQSM

FOXO3

566

O43524
SISKNSPNNMSLSNQ

SSBP2

316

P81877
SNLKLMPSNQQHKTD

SMCHD1

1306

A6NHR9
QQPQHSSSSNGVKME

MYEF2

41

Q9P2K5
PMQLHLQNVTATSAN

RIMBP3

996

Q9UFD9
TNQMTPEKHLNSLGN

SPATA31A6

351

Q5VVP1
TMNQATSSTPNLQLH

NAV2

2256

Q8IVL1
LNAFSQAPSTMQVSH

SRF

431

P11831
SSRHLMKNNPGQAQQ

SLX4IP

366

Q5VYV7
SFHQPTQPVAKNTSM

UBE2J1

236

Q9Y385
HSLQPSISQKSVFQM

RNF168

551

Q8IYW5
MSKQNPAANKTNYSH

MTFR2

246

Q6P444
SPNSTVRKQAMHSLQ

TRRAP

1251

Q9Y4A5
NMKLNSHFPSNESSV

MX2

606

P20592
NQGKVLPQNMTTTHA

ART4

106

Q93070