Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C1 AKR1C2 AKR1C3

1.56e-0641473GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C1 AKR1C2 AKR1C3

1.56e-0641473GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C1 AKR1C2 AKR1C3

1.56e-0641473GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C1 AKR1C2 AKR1C3

3.87e-0651473GO:0047787
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A8 SLC4A4 SLC4A9

7.69e-0661473GO:0008510
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C1 AKR1C2 AKR1C3

7.69e-0661473GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

1.34e-0571473GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

2.13e-0581473GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

2.13e-0581473GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C1 AKR1C2 AKR1C3

2.13e-0581473GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

3.18e-0591473GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C1 AKR1C2 AKR1C3

3.18e-0591473GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

4.52e-05101473GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C1 AKR1C2 AKR1C3

4.52e-05101473GO:0032052
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A8 SLC22A6 SLC4A4 SLC4A9

8.64e-05321474GO:0005452
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A8 SLC4A4 SLC4A9

1.06e-04131473GO:0140410
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

1.34e-04141473GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

1.34e-04141473GO:0001758
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A9

1.61e-0431472GO:0140892
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

3.20e-0441472GO:0047718
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

4.07e-04201473GO:0004303
GeneOntologyMolecularFunctioncargo receptor activity

INSR CD163 LRP8 STAB1 LSR

4.13e-04851475GO:0038024
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate binding

WASHC2C ATG2B OBSCN VPS13B

4.27e-04481474GO:0032266
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP8 STAB1 LSR

4.72e-04211473GO:0030228
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

7.06e-04241473GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

8.98e-04261473GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C1 AKR1C2 AKR1C3

8.98e-04261473GO:0070402
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

1.00e-03271473GO:0008106
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EPHB4 CRIM1 INSR EPHA10

1.35e-03651474GO:0004714
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

1.37e-03301473GO:0018455
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A8 SLC4A4 SLC4A9

1.66e-03321473GO:0015106
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

1.66e-03321473GO:0004033
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

1.81e-03331473GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

1.98e-03341473GO:0016628
GeneOntologyMolecularFunctionlipoprotein particle binding

LRP8 STAB1 LSR

2.15e-03351473GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

LRP8 STAB1 LSR

2.15e-03351473GO:0071814
GeneOntologyMolecularFunctiontranscription regulator activator activity

DDIT3 NSD3

2.33e-03101472GO:0140537
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C3

2.83e-03111472GO:0030283
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

2.94e-03391473GO:0016229
GeneOntologyMolecularFunctioncollagen binding

NID2 MAP1A P3H1 USH2A

3.02e-03811474GO:0005518
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C1 AKR1C2 AKR1C3

3.16e-03401473GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

AKR1C1 AKR1C2 P3H1 AKR1C3 TET3 KDM6A

3.17e-031941476GO:0016705
GeneOntologyMolecularFunctioncAMP response element binding protein binding

DDIT3 CREB3

3.38e-03121472GO:0008140
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB4 CRIM1 INSR EPHA10

3.60e-03851474GO:0019199
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A8 SLC4A9

3.98e-03131472GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A8 SLC4A9

3.98e-03131472GO:0140829
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

EPHB4 CRIM1 INSR ITK EPHA10

4.41e-031451475GO:0004713
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

5.31e-03481473GO:0016620
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT6A MCM3AP

5.31e-03151472GO:0010484
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP8 STAB1

6.04e-03161472GO:0005041
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB1 LSR

7.62e-03181472GO:0030169
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C1 AKR1C2 AKR1C3

1.38e-0641463GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C1 AKR1C2 AKR1C3

1.38e-0641463GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C1 AKR1C2 AKR1C3

1.38e-0641463GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C1 AKR1C2 AKR1C3

1.38e-0641463GO:0008208
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

3.44e-0651463GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

6.84e-0661463GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C1 AKR1C2 AKR1C3

6.84e-0661463GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C1 AKR1C2 AKR1C3

1.19e-0571463GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C1 AKR1C2 AKR1C3

1.19e-0571463GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.19e-0571463GO:1900052
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C1 AKR1C2 AKR1C3

2.83e-0591463GO:0044597
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C1 AKR1C2 AKR1C3

4.02e-05101463GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

4.02e-05101463GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C1 AKR1C2 AKR1C3

4.02e-05101463GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C1 AKR1C2 AKR1C3

4.02e-05101463GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C1 AKR1C2 AKR1C3

4.02e-05101463GO:0030647
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C1 AKR1C2 RBM20 AKR1C3

4.32e-05281464GO:0048025
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C1 AKR1C2 RBM20 AKR1C3

4.99e-05291464GO:0050686
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3

5.50e-05111463GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

5.50e-05111463GO:0016115
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C1 AKR1C2 RBM20 AKR1C3

8.40e-05331464GO:0033119
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.19e-04141463GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

1.19e-04141463GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.49e-04151463GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.82e-04161463GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C1 AKR1C2 AKR1C3

1.82e-04161463GO:0032351
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C1 AKR1C2 AKR1C3

2.62e-04181463GO:0030656
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C1 AKR1C2 AKR1C3

4.21e-04211463GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

4.21e-04211463GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C1 AKR1C2 AKR1C3

4.21e-04211463GO:0048385
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C1 AKR1C2 AKR1C3

4.21e-04211463GO:0042574
GeneOntologyBiologicalProcessketone catabolic process

AKR1C1 AKR1C2 AKR1C3

4.21e-04211463GO:0042182
GeneOntologyBiologicalProcessheart morphogenesis

EPHB4 ADAMTS19 KAT6A INSR SYNPO2L DVL3 RBM20 SUFU KDM6A

4.80e-043211469GO:0003007
GeneOntologyBiologicalProcessparturition

AKR1C1 AKR1C2 AKR1C3

4.85e-04221463GO:0007567
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C1 AKR1C2 AKR1C3

4.85e-04221463GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C1 AKR1C2 AKR1C3

4.85e-04221463GO:0042448
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C1 AKR1C2 AKR1C3

4.85e-04221463GO:1902644
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C1 AKR1C2 AKR1C3

5.55e-04231463GO:0071379
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C1 AKR1C2 AKR1C3

5.55e-04231463GO:0034310
GeneOntologyBiologicalProcessretrograde axonal transport

MAP1A KIF1A DST

6.31e-04241463GO:0008090
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C1 AKR1C2 AKR1C3

8.02e-04261463GO:0010566
DomainFN3

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LRFN2 LRRN4CL FNDC11 TNR USH2A EPHA10 IL9R

3.73e-1019914214PS50853
DomainFN3_dom

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LRFN2 LRRN4CL FNDC11 TNR USH2A EPHA10 IL9R

7.11e-1020914214IPR003961
Domainfn3

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LRFN2 LRRN4CL TNR USH2A EPHA10

3.96e-0916214212PF00041
DomainFN3

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LRFN2 LRRN4CL TNR USH2A EPHA10

1.77e-0818514212SM00060
DomainIg-like_fold

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LSR LRFN2 HMCN2 LRRN4CL FNDC11 NCAN VSIG10L TNR USH2A EPHA10 PLXNB1 IL9R

1.72e-0670614219IPR013783
Domain-

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LSR LRFN2 LRRN4CL FNDC11 NCAN VSIG10L TNR USH2A EPHA10 PLXNB1 IL9R

2.92e-06663142182.60.40.10
DomainGrowth_fac_rcpt_

EPHB4 NID2 CRIM1 INSR LRP8 STAB1 FBLN2 HMCN2 LTBP2

3.04e-061561429IPR009030
DomainNa/HCO3_transpt

SLC4A8 SLC4A4 SLC4A9

4.26e-0651423IPR003024
DomainEGF-like_CS

EPHB4 NID2 LRP8 STAB1 FBLN2 HMCN2 NRXN2 NCAN LTBP2 TNR EPHA10

5.10e-0626114211IPR013032
DomainEGF_2

EPHB4 NID2 LRP8 STAB1 FBLN2 HMCN2 NRXN2 NCAN LTBP2 TNR EPHA10

5.90e-0626514211PS01186
Domain-

SLC4A8 SLC4A4 SLC4A9

3.50e-05914233.40.1100.10
DomainBand3_cytoplasmic_dom

SLC4A8 SLC4A4 SLC4A9

3.50e-0591423IPR013769
DomainBand_3_cyto

SLC4A8 SLC4A4 SLC4A9

3.50e-0591423PF07565
DomainEGF_CA

NID2 LRP8 STAB1 FBLN2 HMCN2 NCAN LTBP2

4.09e-051221427SM00179
DomainEGF-like_Ca-bd_dom

NID2 LRP8 STAB1 FBLN2 HMCN2 NCAN LTBP2

4.54e-051241427IPR001881
DomainALDOKETO_REDUCTASE_1

AKR1C1 AKR1C2 AKR1C3

4.97e-05101423PS00798
DomainPTrfase/Anion_transptr

SLC4A8 SLC4A4 SLC4A9

4.97e-05101423IPR016152
DomainHCO3_transpt_euk

SLC4A8 SLC4A4 SLC4A9

4.97e-05101423IPR003020
DomainALDOKETO_REDUCTASE_2

AKR1C1 AKR1C2 AKR1C3

4.97e-05101423PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C1 AKR1C2 AKR1C3

4.97e-05101423PS00063
DomainHCO3_cotransp

SLC4A8 SLC4A4 SLC4A9

4.97e-05101423PF00955
DomainAldo/ket_reductase_CS

AKR1C1 AKR1C2 AKR1C3

4.97e-05101423IPR018170
DomainHCO3_transpt_C

SLC4A8 SLC4A4 SLC4A9

4.97e-05101423IPR011531
DomainAldo/keto_reductase

AKR1C1 AKR1C2 AKR1C3

4.97e-05101423IPR020471
DomainEGF_3

NID2 LRP8 STAB1 FBLN2 HMCN2 NRXN2 NCAN LTBP2 TNR

7.94e-052351429PS50026
DomainEGF_Ca-bd_CS

NID2 LRP8 FBLN2 HMCN2 NCAN LTBP2

9.73e-05971426IPR018097
DomainEGF_CA

NID2 LRP8 FBLN2 HMCN2 NCAN LTBP2

1.09e-04991426PS01187
DomainASX_HYDROXYL

NID2 LRP8 FBLN2 HMCN2 NCAN LTBP2

1.15e-041001426PS00010
DomainEGF-like_dom

NID2 LRP8 STAB1 FBLN2 HMCN2 NRXN2 NCAN LTBP2 TNR

1.23e-042491429IPR000742
DomainEGF_1

LRP8 STAB1 FBLN2 HMCN2 NRXN2 NCAN LTBP2 TNR USH2A

1.48e-042551429PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 LRP8 FBLN2 HMCN2 NCAN LTBP2

1.59e-041061426IPR000152
Domain-

AKR1C1 AKR1C2 AKR1C3

2.24e-041614233.20.20.100
DomainNADP_OxRdtase_dom

AKR1C1 AKR1C2 AKR1C3

2.71e-04171423IPR023210
DomainAldo_ket_red

AKR1C1 AKR1C2 AKR1C3

2.71e-04171423PF00248
DomainAldo/ket_red/Kv-b

AKR1C1 AKR1C2 AKR1C3

2.71e-04171423IPR001395
DomainG2F

NID2 HMCN2

3.41e-0441422PF07474
DomainNIDOGEN_G2

NID2 HMCN2

3.41e-0441422PS50993
DomainGFP

NID2 HMCN2

3.41e-0441422IPR009017
DomainG2_nidogen/fibulin_G2F

NID2 HMCN2

3.41e-0441422IPR006605
DomainEGF

NID2 LRP8 STAB1 NRXN2 NCAN LTBP2

4.05e-041261426PF00008
DomainEGF

NID2 LRP8 STAB1 FBLN2 NRXN2 NCAN LTBP2 TNR

4.40e-042351428SM00181
DomainEGF_CA

NID2 LRP8 FBLN2 HMCN2 LTBP2

5.03e-04861425PF07645
DomainAutophagy-rel_C

ATG2B VPS13B

5.65e-0451422IPR015412
DomainATG_C

ATG2B VPS13B

5.65e-0451422PF09333
DomainPROTEIN_KINASE_TYR

EPHB4 INSR OBSCN ITK EPHA10

8.71e-04971425PS00109
DomainTyr_kinase_AS

EPHB4 INSR OBSCN ITK EPHA10

8.71e-04971425IPR008266
DomainSH3

ARHGEF19 OBSCN RUSC1 ARHGEF16 ITK DST MYO15A

1.34e-032161427PS50002
DomainSH3_domain

ARHGEF19 OBSCN RUSC1 ARHGEF16 ITK DST MYO15A

1.48e-032201427IPR001452
DomainHis_Pase_clade-2

MINPP1 PPIP5K1

1.56e-0381422IPR000560
DomainChorein_N

ATG2B VPS13B

1.56e-0381422PF12624
DomainVPS13_N

ATG2B VPS13B

1.56e-0381422IPR026854
DomainHis_Phos_2

MINPP1 PPIP5K1

1.56e-0381422PF00328
DomainIGc2

PRTG SDK2 OBSCN DSCAML1 LRFN2 HMCN2 VSIG10L

2.16e-032351427SM00408
DomainIg_sub2

PRTG SDK2 OBSCN DSCAML1 LRFN2 HMCN2 VSIG10L

2.16e-032351427IPR003598
DomainGFP-like

NID2 STAB1

3.02e-03111422IPR023413
Domain-

NID2 STAB1

3.02e-031114222.40.155.10
DomainPkinase_Tyr

EPHB4 INSR ITK GUCY2D EPHA10

3.07e-031291425PF07714
DomainIg_I-set

PRTG SDK2 OBSCN DSCAML1 LRFN2 HMCN2

3.34e-031901426IPR013098
DomainI-set

PRTG SDK2 OBSCN DSCAML1 LRFN2 HMCN2

3.34e-031901426PF07679
DomainEGF_dom

NID2 STAB1

3.60e-03121422IPR024731
DomainEGF_3

NID2 STAB1

3.60e-03121422PF12947
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB4 INSR ITK GUCY2D EPHA10

4.09e-031381425IPR001245
DomainLink_dom

STAB1 NCAN

4.24e-03131422IPR000538
DomainXlink

STAB1 NCAN

4.24e-03131422PF00193
DomainLINK_2

STAB1 NCAN

4.24e-03131422PS50963
DomainLINK

STAB1 NCAN

4.24e-03131422SM00445
DomainLINK_1

STAB1 NCAN

4.24e-03131422PS01241
DomainTyr_kinase_cat_dom

EPHB4 INSR ITK EPHA10

4.56e-03881424IPR020635
DomainTyrKc

EPHB4 INSR ITK EPHA10

4.56e-03881424SM00219
DomainRECEPTOR_TYR_KIN_V_2

EPHB4 EPHA10

4.92e-03141422PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHB4 EPHA10

4.92e-03141422PS00790
DomainTyr_kinase_rcpt_V_CS

EPHB4 EPHA10

4.92e-03141422IPR001426
DomainEphA2_TM

EPHB4 EPHA10

4.92e-03141422PF14575
DomainEphrin_rcpt_lig-bd_dom

EPHB4 EPHA10

4.92e-03141422IPR001090
DomainEph_TM

EPHB4 EPHA10

4.92e-03141422IPR027936
DomainEPH_lbd

EPHB4 EPHA10

4.92e-03141422SM00615
DomainEphrin_lbd

EPHB4 EPHA10

4.92e-03141422PF01404
DomainLdl_recept_b

NID2 LRP8

4.92e-03141422PF00058
DomainLDLRB

NID2 LRP8

4.92e-03141422PS51120
DomainTyr_kinase_ephrin_rcpt

EPHB4 EPHA10

4.92e-03141422IPR016257
DomainEPH_LBD

EPHB4 EPHA10

4.92e-03141422PS51550
DomainIG

PRTG SDK2 OBSCN DSCAML1 LSR LRFN2 HMCN2 NCAN VSIG10L

4.95e-034211429SM00409
DomainIg_sub

PRTG SDK2 OBSCN DSCAML1 LSR LRFN2 HMCN2 NCAN VSIG10L

4.95e-034211429IPR003599
DomainLY

NID2 LRP8

5.65e-03151422SM00135
DomainLDLR_classB_rpt

NID2 LRP8

5.65e-03151422IPR000033
DomainSH3

ARHGEF19 OBSCN RUSC1 ARHGEF16 ITK MYO15A

6.21e-032161426SM00326
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C1 AKR1C2 AKR1C3

3.75e-0591103M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C1 AKR1C2 AKR1C3

3.75e-0591103M47817
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 SLC4A4 SLC4A9

5.33e-05101103M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A8 SLC4A4 SLC4A9

5.33e-05101103MM15073
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C1 AKR1C2 AKR1C3

7.29e-05111103M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 OSBPL6 AKR1C3

1.21e-04331104M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 OSBPL6 AKR1C3

1.21e-04331104MM14737
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.25e-04131103M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.25e-04131103MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

1.58e-04141103M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.58e-04141103M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

1.58e-04141103M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.58e-04141103MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C1 AKR1C2 AKR1C3

1.96e-04151103MM14870
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 OSBPL6 AKR1C3

3.75e-04441104M499
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C1 AKR1C2 LRP8 AKR1C3

4.09e-04451104MM15344
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 OSBPL6 AKR1C3

4.09e-04451104MM14751
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

7.31e-04231103M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C1 AKR1C2 AKR1C3

7.31e-04231103MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

7.31e-04231103MM14741
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C1 AKR1C2 LRP8 GUCY2D AKR1C3

7.57e-04921105MM14881
PathwayREACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR

EXTL1 DDIT3 KLHDC3 EXOSC6 CREB3

7.95e-04931105M10294
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 DPH2 ARHGEF19 KAT6A OBSCN CEP192 TNRC6C CLDN23 MYORG NSD3 SCAF1 DST IL17RE NBEAL2 MCM3AP EXOSC6 KBTBD11 SUFU CREB3 RAB11FIP3

6.04e-0811051492035748872
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

7.71e-083149319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

7.71e-083149331780644
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

7.71e-083149321232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

7.71e-083149313678667
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FAM234B WASHC2C ANGEL1 OBSCN CEP192 GALNT7 AKR1C1 AKR1C2 PRDM2 KLHDC3 FMN1 AKR1C3 BOP1 PJA1 OTULINL NLRP4 VPS13B PLXNB1 RAB11FIP3

2.17e-0710841491911544199
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149320124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C1 AKR1C2 AKR1C3

3.07e-074149310500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149316508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149319487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149314967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149310393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149315193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149331479646
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149315222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149316191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149315577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149310702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149317034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149317629694
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149329764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149310526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149317888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149317442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149328329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149316018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149317272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149319237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149318667791
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149328259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149321521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

3.07e-07414938274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149316511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149310803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C1 AKR1C2 AKR1C3

3.07e-074149334590152
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

3.07e-07414937789999
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C1 AKR1C2 AKR1C3

7.66e-07514937737980
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149321851338
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149317872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149317064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149310672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149338788959
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149315212687
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149316984997
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C1 AKR1C2 AKR1C3

7.66e-075149318003893
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149329107092
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149319273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149315860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149315471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149326748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149317122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C1 AKR1C2 AKR1C3

1.53e-066149317255200
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149326160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149334843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149322529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149333127481
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149319846565
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149312562828
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C1 AKR1C2 AKR1C3

2.66e-067149316337335
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C1 AKR1C2 AKR1C3

4.25e-068149333584538
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C1 AKR1C2 AKR1C3

4.25e-068149320837989
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C1 AKR1C2 AKR1C3

4.25e-06814939224647
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C1 AKR1C2 AKR1C3

6.35e-069149333348080
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C1 AKR1C2 AKR1C3

9.05e-0610149336313771
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C1 AKR1C2 AKR1C3

1.65e-0512149321256921
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C1 AKR1C2 AKR1C3

1.65e-0512149328893949
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C1 AKR1C2 AKR1C3

1.65e-0512149325774556
Pubmed

Co-expression of mesothelin and CA125 correlates with unfavorable patient outcome in pancreatic ductal adenocarcinoma.

MUC16 MSLN

1.82e-052149221775916
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

1.82e-05214928573067
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

1.82e-052149211514561
Pubmed

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.

AKR1C1 AKR1C2

1.82e-052149215492289
Pubmed

Local androgen inactivation in abdominal visceral adipose tissue.

AKR1C2 AKR1C3

1.82e-052149214671194
Pubmed

Difference in mesothelin-binding ability of serum CA125 between patients with endometriosis and epithelial ovarian cancer.

MUC16 MSLN

1.82e-052149225197000
Pubmed

Two clusters of surface-exposed amino acid residues enable high-affinity binding of retinal degeneration-3 (RD3) protein to retinal guanylyl cyclase.

GUCY2D RD3

1.82e-052149232493772
Pubmed

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors.

MUC16 MSLN

1.82e-052149217067392
Pubmed

A binding domain on mesothelin for CA125/MUC16.

MUC16 MSLN

1.82e-052149219075018
Pubmed

Genetic and physical maps of the mouse rd3 locus; exclusion of the ortholog of USH2A.

USH2A RD3

1.82e-052149210384036
Pubmed

AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer.

AKR1C1 AKR1C3

1.82e-052149216338060
Pubmed

Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.

AKR1C1 AKR1C3

1.82e-052149223165153
Pubmed

AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants.

AKR1C2 AKR1C3

1.82e-052149233675863
Pubmed

Transcriptomic Profiling Reveals AKR1C1 and AKR1C3 Mediate Cisplatin Resistance in Signet Ring Cell Gastric Carcinoma via Autophagic Cell Death.

AKR1C1 AKR1C3

1.82e-052149234830394
Pubmed

Does CA125 binding to mesothelin impact the detection of malignant mesothelioma?

MUC16 MSLN

1.82e-052149223357461
Pubmed

cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase.

AKR1C1 AKR1C2

1.82e-05214928011662
Pubmed

Co-Expression of Mesothelin and CA125 Is Associated with the Poor Prognosis of Endometrial Serous Carcinoma and Mixed Carcinomas Including Serous Carcinoma.

MUC16 MSLN

1.82e-052149232468249
Pubmed

Significance of mesothelin and CA125 expression in endometrial carcinoma: a retrospective analysis.

MUC16 MSLN

1.82e-052149233832498
Pubmed

Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.

AKR1C1 AKR1C2

1.82e-052149218654764
Pubmed

Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV-negative tumors is an indicator of poor prognosis.

AKR1C1 AKR1C3

1.82e-052149230367463
Pubmed

Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

AKR1C1 AKR1C2

1.82e-052149221217827
Pubmed

The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death.

AKR1C1 AKR1C2

1.82e-052149226934124
Pubmed

cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.

AKR1C1 AKR1C2

1.82e-05214928486699
Pubmed

Coexpression of MUC16 and mesothelin is related to the invasion process in pancreatic ductal adenocarcinoma.

MUC16 MSLN

1.82e-052149222320398
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SDK2 SMCHD1 KIAA1549 STAB1 STOX2 DST NRXN2 NBEAL2 KBTBD11 BOP1 PLXNB1

1.90e-055291491114621295
Pubmed

An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.

AKR1C1 AKR1C2 MYORG AKR1C3

1.91e-0537149421362171
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C1 AKR1C2 AKR1C3

2.14e-0513149311682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C1 AKR1C2 AKR1C3

2.14e-0513149317062636
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C1 AKR1C2 AKR1C3

2.14e-0513149315117747
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C1 AKR1C2 AKR1C3

2.14e-0513149324580729
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

AKR1C1 AKR1C2 AKR1C3

2.71e-0514149319955443
Pubmed

Placental endocrine function shapes cerebellar development and social behavior.

AKR1C1 AKR1C2 AKR1C3

2.71e-0514149334400844
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

REXO4 INCENP INSR ANGEL1 MUC16 CEP192 GPRIN1 LSR DST DTWD2 KBTBD11 PJA1 EPB41

3.23e-057771491335844135
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

6.79e-076150310p15-p14
Cytoband11q12.3

INCENP SLC22A6 LRRN4CL

2.65e-0438150311q12.3
GeneFamilyFibronectin type III domain containing

EPHB4 IL12RB2 PRTG SDK2 INSR OBSCN DSCAML1 LRFN2 LRRN4CL TNR USH2A EPHA10

9.20e-1116010112555
GeneFamilyAldo-keto reductases

AKR1C1 AKR1C2 AKR1C3

7.33e-05151013399
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PRTG SDK2 OBSCN DSCAML1 LRFN2 HMCN2

2.87e-041611016593
GeneFamilyFibulins

FBLN2 HMCN2

8.46e-0481012556
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL12RB2 IL17RE IL9R

1.66e-03421013602
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHB4 EPHA10

2.69e-031410121095
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GPRASP1 ZCCHC12 SLC4A8 CRIM1 KIF1A SAMD8 KIAA1549 RUSC1 TNRC6C AKR1C1 DSCAML1 AKR1C2 PRDM2 STOX2 TCERG1 NRXN2 NCAN KBTBD11 OSBPL6 EPB41

4.84e-06110614920M39071
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

HECW1 INSR KIAA1549 TNRC6C ZC3H6 PTH1R PARP10 SLC22A6 LRFN2 FMN1 SLC4A4 RAB11FIP3

5.01e-0641714912M39224
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C1 DSCAML1 AKR1C2 AKR1C3

1.16e-05251494MM480
CoexpressionHIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN

CRIM1 RUSC1 GALNT7 RGS20 DST WDR73

2.62e-051021496M2124
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

HECW1 INSR KIAA1549 DSCAML1 PTH1R SLC22A6 STOX2 SLC4A4 RAB11FIP3

1.53e-081871509738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN PKD1L2 DSCAML1 SLC4A4 MYO15A USH2A EPHA10

2.15e-0718415082cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN PKD1L2 DSCAML1 SLC4A4 MYO15A USH2A EPHA10

2.15e-071841508ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OBSCN PKD1L2 DSCAML1 SLC4A4 MYO15A USH2A EPHA10

2.15e-0718415082b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HECW1 INSR DSCAML1 PTH1R SLC22A6 STOX2 SLC4A4 RAB11FIP3

2.24e-0718515081bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell368C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MAP1A KIAA1549 ITK OSBPL6 KIAA2012 IL9R RD3

2.04e-0617315078cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell368C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MAP1A KIAA1549 ITK OSBPL6 KIAA2012 IL9R RD3

2.04e-061731507fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF19 CRIM1 INCENP MUC16 EXTL1 IL17RE MSLN

2.46e-061781507c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

INSR DSCAML1 PTH1R SLC22A6 STOX2 SLC4A4 RAB11FIP3

2.65e-061801507358923e4228035a3e90e2957392089219e90dcd7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR PTH1R SLC22A6 OSBPL6 SLC4A4 RAB11FIP3

2.65e-0618015071363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

INSR DSCAML1 RBM20 PTH1R LTBP2 SUFU USH2A

2.75e-061811507c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM174B KIAA1549 STAB1 FBLN2 CBX6 NCAN OSBPL6

2.96e-0618315076f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.54e-061881507f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.54e-0618815070792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.66e-061891507204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.66e-06189150713fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 SLC4A8 CRIM1 NRXN2 LTBP2 PJA1 OTULINL

4.50e-0619515074a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 SLC4A8 CRIM1 NRXN2 LTBP2 PJA1 OTULINL

4.50e-0619515077a32a8535c29b819dacba901d0658280a2631c94
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EYA4 SLC4A8 INSR MUC16 GALNT7 AKR1C1 DTWD2

4.97e-061981507af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NID2 DSCAML1 PTH1R LSR IL17RE NBEAL2 PLXNB1

5.31e-062001507ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1549 BIRC7 OSBPL6 KIAA2012 IL9R RD3

1.29e-051521506faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1549 BIRC7 OSBPL6 KIAA2012 IL9R RD3

1.29e-051521506519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellCiliated_cells-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

MAP1A LKAAEAR1 MUC16 FNDC11 OSBPL6 SLC4A9

1.85e-0516215065319603f7ba3f48126dcf2ba9ae604be11bf2577
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

KIF27 LKAAEAR1 MUC16 OSBPL6 KIAA2012 LRRC23

2.20e-05167150626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 PRTG CRIM1 FAM174B STAB1 SLC4A9

2.27e-05168150606dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 PRTG CRIM1 FAM174B STAB1 SLC4A9

2.27e-0516815061002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellmild_COVID-19_(asymptomatic)-RBC|World / disease group, cell group and cell class (v2)

ANGEL1 IRAK1BP1 MINPP1 ZNF74 SLC4A4 LRRC23

2.35e-0516915062bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 SH3BGR OBSCN RBM20 CD163 FMN1

2.43e-0517015063f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

SH3BGR OBSCN RBM20 CD163 STAB1 FMN1

2.43e-0517015064232fe937909f93d3736988c707b8f95ce993398
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 FAM174B STAB1 LRRN4CL NRXN2 RAB11FIP3

2.51e-051711506686f95892c3909973c66c9a27159a070a068f175
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 FAM174B STAB1 LRRN4CL NRXN2 RAB11FIP3

2.51e-051711506f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EYA4 MUC16 AKR1C1 AKR1C2 SLC4A4 MSLN

2.51e-05171150625c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellPND14-Endothelial-Endothelial_lymphatic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 FAM174B STAB1 LRRN4CL NRXN2 RAB11FIP3

2.51e-051711506d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR PTH1R SLC22A6 SLC4A4 RAB11FIP3

2.51e-051711506f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 FAM174B STAB1 LRRN4CL NRXN2 RAB11FIP3

2.51e-051711506fbf8e9db00573adcada4b25730e191417b7c9999
ToppCellmild_COVID-19_(asymptomatic)-RBC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ANGEL1 IRAK1BP1 MINPP1 ZNF74 SLC4A4 LRRC23

2.51e-05171150678491478ba65bad45238fe114f5251b2adea323d
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EYA4 MUC16 AKR1C1 AKR1C2 SLC4A4 MSLN

2.51e-051711506fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PTH1R SLC22A6 OSBPL6 SLC4A4 RAB11FIP3

2.68e-0517315068888434641ea554a9b62c436e87920378eef29cd
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

PRTG LKAAEAR1 BIRC7 LCT STOX2 AKR1C3

2.77e-0517415066d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 EXTL1 LRP8 LSR UBA7 FMN1

2.95e-05176150624b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 MUC16 FBLN2 LRRN4CL IL17RE MSLN

2.95e-0517615068e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 MUC16 FBLN2 LRRN4CL IL17RE MSLN

2.95e-051761506ed575330a08a6748ea4b28433292c8cfd157d444
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC4A8 EXTL1 LRP8 LSR UBA7 FMN1

3.05e-051771506f360f7099570d248531897b96e0de282e58f59e9
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

KIF1A SAMD8 TNRC6C DSCAML1 DST TNR

3.05e-051771506e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HECW1 KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.15e-05178150623a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC4A8 EXTL1 MYORG FBLN2 LRRN4CL MSLN

3.25e-051791506adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3BGR OBSCN KIAA1549 CD163 LRP8 NRXN2

3.25e-051791506d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.35e-051801506f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 KIAA1549 SLC22A6 STOX2 SLC4A4 RAB11FIP3

3.45e-0518115069542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 KIAA1549 SLC22A6 STOX2 SLC4A4 RAB11FIP3

3.45e-0518115068f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.67e-05183150684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ARHGEF19 ANGEL1 P3H1 AKR1C3 OTULINL EPB41

3.79e-0518415069cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCellIPF-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

PIM2 KIAA1549 ITK OSBPL6 IL9R RD3

3.79e-0518415067326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

HECW1 KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

3.79e-051841506dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

PIM2 SMCHD1 DSCAML1 ITK NSD3 EPB41

3.79e-05184150622c15ce30171c687ab564f4383ae74d38b759272
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 STAB1 STOX2 LRRN4CL NRXN2 WDR73

3.90e-0518515063a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A KIAA1549 EXTL1 ARHGEF16 DCT PLXNB1

3.90e-05185150611c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 STAB1 STOX2 LRRN4CL NRXN2 WDR73

3.90e-051851506224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

EYA4 MUC16 AKR1C1 AKR1C2 CATSPERB SLC4A4

4.02e-051861506d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

CEP192 FBLN2 LRRN4CL NRXN2 P3H1 SUFU

4.02e-0518615061bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

CEP192 FBLN2 LRRN4CL NRXN2 P3H1 SUFU

4.02e-05186150659db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR PTH1R SLC22A6 SLC4A4 RAB11FIP3

4.02e-0518615068287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 INSR PTH1R SLC22A6 SLC4A4 RAB11FIP3

4.14e-05187150671eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

4.14e-051871506dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM174B CLDN23 LSR IL17RE NBEAL2 KBTBD11

4.14e-051871506aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 KIAA1549 PTH1R SLC22A6 SLC4A4 RAB11FIP3

4.14e-051871506f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

HECW1 AKR1C1 SLC22A6 OSBPL6 SLC4A4 RAB11FIP3

4.14e-051871506acd305475f3609800af0d7bc68d83ef41228080b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

4.27e-0518815065901b276f2379abf486b8285957277e95f08464e
ToppCellMesenchymal_cells-Osteoblasts|World / Lineage and Cell class

ARHGEF19 SDK2 PTH1R ZNF469 P3H1 PLXNB1

4.27e-05188150689f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EXTL1 AKR1C1 DSCAML1 NRXN2 AKR1C3 TNR

4.53e-0519015066c7e1086c0a274cd5527c3104106e372811c9905
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PTH1R SLC22A6 STOX2 SLC4A4 RAB11FIP3

4.66e-0519115063c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PTH1R SLC22A6 STOX2 SLC4A4 RAB11FIP3

4.66e-0519115061c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NID2 SLC39A1 PTH1R FBLN2 LRRN4CL LTBP2

4.94e-0519315065bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ADAMTS19 AKR1C1 AKR1C2 FBLN2 CATSPERB LTBP2

4.94e-051931506dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EYA4 SLC4A8 MUC16 AKR1C1 AKR1C2 SLC4A4

5.08e-051941506e0228f593c3493175962a4817500d4337ddc4e88
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC4A8 INSR MUC16 GALNT7 SLC4A4 MSLN

5.23e-0519515062a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

GPRASP1 KAT6A OBSCN TNRC6C ITK EPB41

5.23e-0519515064bdedd924564a260841a9153604026b57487c83d
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC4A8 INSR MUC16 GALNT7 SLC4A4 MSLN

5.23e-051951506576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC4A8 INSR MUC16 GALNT7 SLC4A4 MSLN

5.23e-0519515068f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

EYA4 FAM174B DST NBEAL2 OTULINL MSLN

5.23e-051951506792d6a49b0a875a00569071183d195287a9925c5
ToppCellCOVID-19-Lymphoid-Tregs|COVID-19 / Condition, Lineage and Cell class

IL12RB2 PIM2 SMCHD1 ITK NSD3 EPB41

5.23e-051951506284cfff4d59ecc1430997b118de17fee167dcbb1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.38e-051961506c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

WASHC2C CD163 NSD3 STAB1 FMN1 OTULINL

5.38e-05196150615397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAM174B DST IL17RE NBEAL2 OTULINL MSLN

5.38e-0519615066731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZCCHC12 SLC4A8 KIF1A GPRIN1 AKR1C1 LRFN2

5.38e-051961506afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

WASHC2C CD163 NSD3 STAB1 FMN1 OTULINL

5.38e-051961506f245e929a286cb097130572e1027b4f01be8b04d
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAM174B DST IL17RE NBEAL2 OTULINL MSLN

5.38e-0519615066856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.38e-051961506057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 SLC4A8 CRIM1 LTBP2 PJA1 OTULINL

5.38e-0519615066708026bafd19c35c5c4e81911344d36a0f508cd
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CRIM1 SLC39A1 FAM174B STAB1 NRXN2

5.53e-051971506d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CRIM1 SLC39A1 FAM174B STAB1 NRXN2

5.53e-051971506412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.53e-051971506ff19e4c45715752a04541ad6a0cdf5454c9daaa2
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.53e-0519715063f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

NID2 PTH1R IL17RE NBEAL2 AKR1C3 PLXNB1

5.69e-05198150685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

C3orf20 AKR1C1 LSR AKR1C3 MSLN LRRC23

5.69e-0519815066712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.69e-051981506778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MUC16 GALNT7 AKR1C1 AKR1C2 LSR MSLN

5.69e-0519815067d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR MUC16 GALNT7 AKR1C1 SLC4A4 MSLN

5.69e-0519815067896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

SDK2 MAP1A OBSCN OSBPL6 RD3

5.84e-0512215052aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCell356C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAP1A AKR1C2 FBLN2 LRRN4CL AKR1C3 MPG

5.85e-051991506beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

2.69e-0731483ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

2.69e-0731483ctd:C007201
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

2.69e-0731483ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

2.69e-0731483ctd:C530610
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

1.07e-0641483ctd:C005522
DrugPregnanes

AKR1C1 AKR1C2 AKR1C3

1.07e-0641483ctd:D011278
Drugtetralol

AKR1C1 AKR1C2 AKR1C3

1.07e-0641483ctd:C019106
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

1.07e-0641483ctd:C010969
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C1 AKR1C2 AKR1C3

1.07e-0641483ctd:C018156
DrugHydroxysteroids

AKR1C1 AKR1C2 AKR1C3

2.67e-0651483ctd:D006914
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

2.67e-0651483CID000257630
Drugcresolphthalein

AKR1C1 AKR1C2 AKR1C3

2.67e-0651483ctd:C010092
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

5.31e-0661483ctd:D004949
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

5.31e-0661483ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

5.31e-0661483ctd:C023723
DrugMedazepam

AKR1C1 AKR1C2 AKR1C3

5.31e-0661483ctd:D008472
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1C3

9.24e-0671483ctd:C117714
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

9.24e-0671483ctd:C020549
DrugNitrazepam

AKR1C1 AKR1C2 AKR1C3

1.47e-0581483ctd:D009567
Drug4-hydroxybenzoic acid

AKR1C1 AKR1C2 AKR1C3

2.20e-0591483ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C1 AKR1C2 AKR1C3

2.20e-0591483ctd:D004092
Drugoctyl gallate

AKR1C1 AKR1C2 AKR1C3

3.12e-05101483ctd:C016627
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

4.20e-0521482ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

4.20e-0521482DB07768
Drugbaccharin

AKR1C2 AKR1C3

4.20e-0521482ctd:C012764
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

EPHB4 INCENP NSD3 MCM3AP KBTBD11 ZNF74 SNAPC2 WDR48

4.25e-0519514883191_DN
DrugDihydroxydihydrobenzopyrenes

AKR1C1 AKR1C2 AKR1C3

4.27e-05111483ctd:D004101
Drugchlordecone alcohol

AKR1C1 AKR1C2 AKR1C3

4.27e-05111483CID000013946
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A

EPHB4 NID2 SLC4A8 MAP1A KIF1A INSR DNAH17 RAB11FIP3

4.90e-0519914886624_DN
Drugfenamic acid

AKR1C1 AKR1C2 AKR1C3

5.67e-05121483ctd:C001209
DrugPhenolphthalein

AKR1C1 AKR1C2 AKR1C3

5.67e-05121483ctd:D020113
DrugDMBA-3,4-dihydrodiol

AKR1C1 AKR1C2 AKR1C3

7.34e-05131483CID000050096
Drugflunisolide

AKR1C1 AKR1C2 AKR1C3

7.34e-05131483ctd:C007734
DrugDydrogesterone

AKR1C1 AKR1C2 AKR1C3

9.30e-05141483ctd:D004394
Drug5-alpha-Dihydroprogesterone

AKR1C1 AKR1C2 AKR1C3

9.30e-05141483ctd:D043582
Drug1-acenaphthenol

AKR1C1 AKR1C2 AKR1C3

9.30e-05141483CID000022750
DrugMeclofenamic Acid

AKR1C1 AKR1C2 AKR1C3

9.30e-05141483ctd:D008469
DrugMefenamic Acid

AKR1C1 AKR1C2 SLC22A6 AKR1C3

1.18e-04391484ctd:D008528
DrugSalicylic Acid

AKR1C1 AKR1C2 SLC22A6 AKR1C3

1.18e-04391484ctd:D020156
DrugAdenosine-5'-[Beta, Gamma-Methylene]Triphosphate

KIF1A INSR

1.25e-0431482DB03909
Drug5-dihydrodeoxycorticosterone

AKR1C1 AKR1C2

1.25e-0431482ctd:C454687
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

1.14e-0731443C0027661
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

1.13e-0651443C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

1.13e-0651443C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

1.13e-0651443C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

1.13e-0651443C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

1.13e-0651443C2930619
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

3.93e-0671443C0036875
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A4 SLC4A9

4.96e-05151443DOID:2355 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

EPHB4 INSR ITK EPHA10

6.94e-05451444C0278701
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

3.50e-0461442EFO_0800552
DiseaseGlaucoma

LTBP2 SLC4A4

8.33e-0491442C0017601
Diseasefish oil supplement exposure measurement, triglyceride measurement

MAP1A NCAN

1.04e-03101442EFO_0004530, EFO_0600007
Diseasecancer antigen 125 measurement

MUC16 MSLN

1.04e-03101442EFO_0010603
DiseaseMedulloblastoma

KAT6A SUFU KDM6A

1.89e-03501443C0025149
DiseaseMetastatic melanoma

EPHB4 ITK GUCY2D

2.35e-03541443C0278883
DiseaseLeber congenital amaurosis

GUCY2D RD3

2.71e-03161442cv:C0339527
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

2.71e-03161442GO_0031427
Diseasepre-malignant neoplasm (biomarker_via_orthology)

INSR SUFU

3.07e-03171442DOID:0060071 (biomarker_via_orthology)
Diseasenevus count

FMN1 RD3

3.44e-03181442EFO_0004632
Diseaseelectrocardiography

CRIM1 SYNPO2L OBSCN RBM20 HMCN2 KBTBD11 OSBPL6 SUFU

4.61e-035301448EFO_0004327

Protein segments in the cluster

PeptideGeneStartEntry
EEPPLQPARWLEASE

BOP1

506

Q14137
VPEPRPSEWDKRLST

EPB41

696

P11171
LEEVTVLPPGRWDPT

SLC4A9

316

Q96Q91
EPILQWTPGDVIPES

CATSPERB

156

Q9H7T0
SPSAPSWREPEVLDL

CBX6

301

O95503
SWREPEVLDLSLPPE

CBX6

306

O95503
RWVDPNSPVLLEDPV

AKR1C3

226

P42330
SVSAPWPEPERESRP

FAM174B

31

Q3ZCQ3
EEPWPIVLSTESPAA

ARHGEF16

66

Q5VV41
ALPPPESELWETPDV

DPH2

396

Q9BQC3
DWPLTAEVPPELLAA

BIRC7

96

Q96CA5
PPLETPLAAEDWETE

C19orf84

171

I3L1E1
WELPVEPAERRPECT

DTWD2

56

Q8NBA8
EPIRPIDPAAWVSHT

DVL3

351

Q92997
LLWEPTAPSPVETFE

ATG2B

966

Q96BY7
PVPWASLLPVVEAVA

C17orf113

351

A0A1B0GUU1
PAVDEQETPLPRSWS

RANBP9

156

Q96S59
PLSLPSWEPEDVFSE

RBM20

1131

Q5T481
RSEAPLPELDPLFSW

RAB11FIP3

111

O75154
LPELDPLFSWTEEPE

RAB11FIP3

116

O75154
EVVFPALWRREPVDP

ADAMTS19

36

Q8TE59
PTLWDSLEEPDIRDP

FMN1

1001

Q68DA7
PFVDPDSWTPEEVIP

P3H1

386

Q32P28
LPSLGEVSQPPEEVW

KIAA1549

301

Q9HCM3
DWSEPRLDTQEEPPL

ARHGEF19

261

Q8IW93
EPAWEEAPPERALEL

CDRT15

106

Q96T59
AAPPDICSRTVWPDE

MMADHC

46

Q9H3L0
PEDVSWPSRPSVEKT

MUC16

8836

Q8WXI7
EEADETETAWPPLPA

LRRN4CL

31

Q8ND94
TPPTRVFVELVPWAD

IRAK1BP1

6

Q5VVH5
RWLAESPVGLPPEEE

MAP1A

1771

P78559
QIVPSLPEWEDSLSP

MAGEC1

531

O60732
EERETPAVPPTWRAS

MAGED4

361

Q96JG8
DLTFDPGPRDLVEPW

EPHB4

376

P54760
AFPDSPWRERVLAPI

INCENP

271

Q9NQS7
VLPEPPRAEDQLWTA

GUCY2D

696

Q02846
REPEDSETPWTVPPL

MYO15A

911

Q9UKN7
DPRIWPGRSTPESDV

NAB2

181

Q15742
ELLEENPDTPEAPRW

DST

4581

Q03001
PAPTWLLDPTRLEEE

EXOSC6

191

Q5RKV6
TIDEPLPPNWEARID

HECW1

826

Q76N89
TLECESWAVPPPTIR

HMCN2

2666

Q8NDA2
DSEITKEDDALWPPP

MAGOH

66

P61326
EPSPWGPLDDVRFLI

MMP24OS

51

A0A0U1RRL7
WTPPRLPVTSEALSE

MCM3AP

1756

O60318
WPTPEDPEPLVISEV

IL12RB2

696

Q99665
QPSDPETWESLPRLD

IL17RE

156

Q8NFR9
LPSIEEAWSLPIPAE

KDM6A

416

O15550
TSLPDAAWIPPTREV

FBLN2

391

P98095
GEEFPEEWLPTPLTE

LRRC23

36

Q53EV4
WEDIPELPPIHSSLA

KIF27

1296

Q86VH2
ALPGLPEDPWVRVEF

PLXNB1

1341

O43157
RDSSPPSLQIEEPEW

FAM234B

351

A2RU67
RVDLPLPPEVWTAAL

NRXN2

636

Q9P2S2
ESSEESTPVWRPPLK

KIAA2012

451

Q0VF49
LNSDWAEPLSPERPE

LCT

601

P09848
PDPRPWTQSLELPAE

LKAAEAR1

91

Q8TD35
VPPVPTLADIAWIAA

MTFR1L

56

Q9H019
PPSSIWAVRPQDLDT

MSLN

461

Q13421
LADLISREWPDPAAP

NLRP4

201

Q96MN2
SREWPDPAAPITEIV

NLRP4

206

Q96MN2
WTVVDIDPPLRSNDP

INSR

556

P06213
EPQSVSLSWREPIPA

EPHA10

466

Q5JZY3
PKEVPAESVTVWIDP

BPNT2

161

Q9NX62
LEPEPVPLSKEADSW

OSBPL6

56

Q9BZF3
PEEPLRDWPEISLLT

OTULINL

331

Q9NUU6
VAPDELPTWILSPQD

PKD1L2

1231

Q7Z442
LTVLAPPSFVEWPES

PRTG

321

Q2VWP7
WEIIQTVPDATPECP

ITGAD

131

Q13349
PEPTPWEDIGQVSLV

OBSCN

7266

Q5VST9
WDERETRSPAPPEVD

NID2

386

Q14112
PPEVDRDSLAPSWET

NID2

396

Q14112
PVDVDPECLRWTPVI

KAT6A

766

Q92794
SPPPDSDLERVFVWD

EYA4

361

O95677
DLDTWTDDTIPKTPP

DNAH17

1016

Q9UFH2
PPTVTWALDDEPIVR

DSCAML1

436

Q8TD84
PAGLLPPEWEEDEER

CHMP7

16

Q8WUX9
SPDPRPFLADWALVE

FNDC11

146

Q9BVV2
LVVLWSSLTPRPDDP

GALNT7

21

Q86SF2
WEELISDPSVPTPSD

C3orf20

51

Q8ND61
DLEVPLWPTPSENDI

CRIM1

896

Q9NZV1
AVWLERGPLEPSEPA

MPG

241

P29372
ALVENSVETRPPPWL

LTBP2

501

Q14767
AARPPLDQLASEEPW

CEP192

2116

Q8TEP8
TRTEAWLDCPPTPVL

KLHDC3

221

Q9BQ90
DPASLAWLTEEEPEP

DDIT3

56

P35638
VAPPEPAEPVRDVSW

GPRIN1

901

Q7Z2K8
PSSPWEKRLASPSEE

CD163

906

Q86VB7
APDEAVRAPLDWALP

CREB3

26

O43889
VRAPLDWALPLSEVP

CREB3

31

O43889
TATQLDVTWEPPPLD

SDK2

1636

Q58EX2
PLPDTVQDLESRWAP

SLC22A6

511

Q4U2R8
STIQVEWPEPDLAPA

CLDN23

206

Q96B33
RTPCAETPAEPVDWA

KIF1A

606

Q12756
PAAISSFDRPLWAEP

LRP8

891

Q14114
PSRGPALTPIRDEEW

LSR

446

Q86X29
WEPQPEPDERLEAAA

PRDM2

246

Q13029
EEEPVAPSTVAPRWL

PARP10

636

Q53GL7
PLPPWQERTDESIET

SDHAF2

51

Q9NX18
PEDNRRPLWEPEETV

ITK

161

Q08881
PDPSRRPQSWEEVTV

GPRASP1

1036

Q5JY77
AKEAAPAPPTEEDIW

REXO4

181

Q9GZR2
DWLIVFSPDTELPPS

RUSC1

341

Q9BVN2
DEPIWRTELASAPVP

SYNPO2L

916

Q9H987
TLEAAPSEVSPPDLW

USH2A

4351

O75445
EATGWEEPSPPSIRR

TNRC6C

706

Q9HCJ0
TWPEGDELLPNEVRP

SMCHD1

696

A6NHR9
LPDIFLDSVPRIPWA

SAMD8

186

Q96LT4
TWVLEPEKPPRSATA

FANCL

211

Q9NW38
DLPTWEESPAPTLEE

RGS20

241

O76081
PSSRPSLEEILLDPW

PIM2

271

Q9P1W9
DVVLPPWASSPEDFI

NBEAL2

2246

Q6ZNJ1
RPATPDLFWSPLEAT

NCAN

596

O14594
WLPSLPDEVFLEEAP

SHROOM1

381

Q2M3G4
EDVERDTPPPLRSWS

RD3

171

Q7Z3Z2
DQVTVLPPGEWDPSI

SLC4A8

391

Q2Y0W8
EDWAPTSLTRPAPPD

IL9R

411

Q01113
PVLLSPRWELPFSEV

EXTL1

296

Q92935
EEPAAPSPEPRVWLE

KBTBD11

101

O94819
SHREEPWVDPNSPVL

AKR1C1

221

Q04828
SHREEPWVDPNSPVL

AKR1C2

221

P52895
EDPAVLAWSIAPEPV

ANGEL1

176

Q9UNK9
LAWSIAPEPVPQEEA

ANGEL1

181

Q9UNK9
PVDPWAAASPDLALA

SH3BGR

21

P55822
PSESAPLDLRLAWDP

ZC3H6

771

P61129
ELDRSADPPPAIWVA

WDR48

301

Q8TAF3
LSGPEAPWRDPELLE

MINPP1

61

Q9UNW1
GTPALPPTEEIWVEN

TCERG1

126

O14776
RPPQPWDPVDAETVV

UBA7

306

P41226
SGPERPPALLQEEWE

PTH1R

576

Q03431
VWRPEAVASEPPVPV

SLC39A1

11

Q9NY26
VSVLDPPDTWVPSRL

SCAF1

101

Q9H7N4
PPEEWPLRDEDTPAT

STOX2

291

Q9P2F5
SPTVEDTPRAKTPDW

FAM170A

206

A1A519
RETGESAPPTWPAEL

SUFU

126

Q9UMX1
NITWSDPSPPADRLI

TNR

791

Q92752
WEPDDAPIPRRNVTA

STAB1

1716

Q9NY15
TPDQELVPASEPVWE

WASHC2C

6

Q9Y4E1
LRAPSWPVVPPEEHS

TET3

401

O43151
AIDLPVSVEETPGWP

DCT

456

P40126
TSAEEEEPPPVKIAW

NSD3

456

Q9BZ95
EEIDAFPRLWTPPED

MRPL13

161

Q9BYD1
TTKGWPETLERPVDP

ZNF469

3491

Q96JG9
IPRPILEEGDAFPWT

VPS13B

1141

Q7Z7G8
VWDVPVEEFPLRCPL

ZNF74

171

Q16587
EVIVLPPGEWDPAIR

SLC4A4

376

Q9Y6R1
ASRPPADITWSLADP

VSIG10L

431

Q86VR7
ESWETLPGKEEREPP

PJA1

391

Q8NG27
RREAQPPAPIEVWTD

SNAPC2

91

Q13487
VPSPDPELLRVTWAP

WDR73

271

Q6P4I2
QIPWSIPTEAEDIPI

PPIP5K1

366

Q6PFW1
DVILVESQDPPLPSW

ZCCHC12

276

Q6PEW1
TPLPTARDRDADPTW

UTF1

186

Q5T230
ASPWEDLRPSPLSET

GARIN5B

821

Q8N5Q1
PSPLIHWVAPDDRLV

LRFN2

316

Q9ULH4
RVPAPEAFRDPIWST

MYORG

306

Q6NSJ0