Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of collagen catabolic process

CST1 CST2 CST4

6.56e-0651813GO:0010711
GeneOntologyBiologicalProcessnegative regulation of elastin catabolic process

CST1 CST2 CST4

6.56e-0651813GO:0060311
GeneOntologyBiologicalProcessregulation of elastin catabolic process

CST1 CST2 CST4

1.30e-0561813GO:0060310
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHGB5 PCDHA1 PCDH20 CRB1 PTPRR PIK3CB PCDHGB4 SPARCL1 CDH3 CDH6 CDH9 ADGRL3

2.19e-0531318112GO:0098742
GeneOntologyBiologicalProcessnegative regulation of blood vessel remodeling

CST1 CST2 CST4

2.27e-0571813GO:0060313
GeneOntologyBiologicalProcessgrowth plate cartilage chondrocyte growth

CST1 CST2 CST4

2.27e-0571813GO:0003430
GeneOntologyBiologicalProcesscerebrospinal fluid circulation

SPEF2 DNAAF11 CFAP221 KATNIP

2.49e-05201814GO:0090660
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHGB5 PCDHA1 PCDH20 PTPRR PIK3CB PCDHGB4 CDH3 CDH6 CDH9

4.20e-051871819GO:0007156
GeneOntologyBiologicalProcessregulation of collagen catabolic process

CST1 CST2 CST4

5.37e-0591813GO:0010710
GeneOntologyBiologicalProcessnegative regulation of extracellular matrix organization

PPARG CST1 CST2 CST4

7.37e-05261814GO:1903054
GeneOntologyBiologicalProcessnegative regulation of extracellular matrix disassembly

CST1 CST2 CST4

7.62e-05101813GO:0010716
GeneOntologyBiologicalProcesselastin catabolic process

CST1 CST2 CST4

7.62e-05101813GO:0060309
GeneOntologyBiologicalProcessgrowth plate cartilage chondrocyte development

CST1 CST2 CST4

7.62e-05101813GO:0003431
GeneOntologyBiologicalProcesschondrocyte hypertrophy

CST1 CST2 CST4

7.62e-05101813GO:0003415
GeneOntologyBiologicalProcessnegative regulation of collagen metabolic process

PPARG CST1 CST2 CST4

9.96e-05281814GO:0010713
GeneOntologyBiologicalProcesschondrocyte development involved in endochondral bone morphogenesis

CST1 CST2 CST4

1.78e-04131813GO:0003433
GeneOntologyBiologicalProcessnegative regulation of glycoprotein metabolic process

CST1 CST2 CST4 ITM2B

1.92e-04331814GO:1903019
GeneOntologyBiologicalProcesselastin metabolic process

CST1 CST2 CST4

2.25e-04141813GO:0051541
GeneOntologyBiologicalProcessgrowth plate cartilage chondrocyte differentiation

CST1 CST2 CST4

2.25e-04141813GO:0003418
MousePhenoruptured lens capsule

TBC1D20 CRYAA PXDN BCAR3

9.71e-06141434MP:0008841
DomainFHA

AGGF1 CEP170 STARD9 MKI67 KIF14 CEP170B

2.41e-07281816SM00240
DomainFHA

AGGF1 CEP170 STARD9 MKI67 KIF14 CEP170B

4.59e-07311816PF00498
Domain-

AGGF1 CEP170 STARD9 MKI67 KIF14 CEP170B

1.17e-063618162.60.200.20
DomainFHA_dom

AGGF1 CEP170 STARD9 MKI67 KIF14 CEP170B

1.17e-06361816IPR000253
DomainSMAD_FHA_domain

AGGF1 CEP170 STARD9 MKI67 KIF14 CEP170B

1.07e-05521816IPR008984
DomainFHA_DOMAIN

AGGF1 CEP170 MKI67 KIF14 CEP170B

1.12e-05311815PS50006
DomainProt_inh_cystat_CS

CST1 CST2 CST4

7.20e-0591813IPR018073
DomainDUF1220

NBPF11 NBPF1 NBPF9

7.20e-0591813SM01148
DomainCadherin_CS

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

9.27e-051091817IPR020894
DomainNID

IFI35 NMI

9.34e-0521812PF07292
DomainIFP_35_N

IFI35 NMI

9.34e-0521812PF07334
DomainCEP170_C

CEP170 CEP170B

9.34e-0521812PF15308
DomainCEP170_C

CEP170 CEP170B

9.34e-0521812IPR029300
DomainNmi/IFP35_N

IFI35 NMI

9.34e-0521812IPR009938
DomainNmi/IFP35_dom

IFI35 NMI

9.34e-0521812IPR009909
DomainFAM21

WASHC2C WASHC2A

9.34e-0521812IPR027308
DomainCADHERIN_1

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.16e-041131817PS00232
DomainCadherin

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.16e-041131817PF00028
DomainCADHERIN_2

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.23e-041141817PS50268
Domain-

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.23e-0411418172.60.40.60
DomainCA

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.30e-041151817SM00112
DomainCadherin-like

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.37e-041161817IPR015919
DomainDUF1220

NBPF11 NBPF1 NBPF9

1.39e-04111813PF06758
DomainNBPF_dom

NBPF11 NBPF1 NBPF9

1.39e-04111813IPR010630
DomainNBPF

NBPF11 NBPF1 NBPF9

1.39e-04111813PS51316
DomainCadherin

PCDHGB5 PCDHA1 PCDH20 PCDHGB4 CDH3 CDH6 CDH9

1.53e-041181817IPR002126
DomainCystatin

CST1 CST2 CST4

1.85e-04121813IPR027214
DomainCYSTATIN

CST1 CST2 CST4

1.85e-04121813PS00287
DomainCAP-ZIP_m

WASHC2C WASHC2A

2.78e-0431812PF15255
DomainFAM21/CAPZIP

WASHC2C WASHC2A

2.78e-0431812IPR029341
DomainMYB_LIKE

MIS18BP1 GON4L TTF1 DNAJC1

4.87e-04381814PS50090
DomainCY

CST1 CST2 CST4

5.51e-04171813SM00043
DomainCystatin_dom

CST1 CST2 CST4

6.56e-04181813IPR000010
DomainCystatin

CST1 CST2 CST4

6.56e-04181813PF00031
DomainMyb-like_dom

GON4L TTF1

1.37e-0361812IPR017877
DomainG_PATCH

GPATCH1 AGGF1 TFIP11

1.37e-03231813PS50174
DomainG_patch

GPATCH1 AGGF1 TFIP11

1.37e-03231813SM00443
DomainG_patch_dom

GPATCH1 AGGF1 TFIP11

1.37e-03231813IPR000467
DomainG-patch

GPATCH1 AGGF1 TFIP11

1.37e-03231813PF01585
DomainSANT

MIS18BP1 GON4L TTF1 DNAJC1

1.39e-03501814SM00717
DomainSANT/Myb

MIS18BP1 GON4L TTF1 DNAJC1

1.61e-03521814IPR001005
DomainCadherin_C

CDH3 CDH6 CDH9

1.76e-03251813PF01049
DomainCadherin_cytoplasmic-dom

CDH3 CDH6 CDH9

1.76e-03251813IPR000233
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF12 NBPF11 NBPF1 NBPF19 NBPF9 NBPF10

1.52e-1121192716079250
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 WASHC2C PPM1E PSD3 GON4L WASHC2A MAP3K4 PXDN STARD9 TLE4 DZIP3 OGFOD1 KATNIP SH3BP5L ANKRD12 R3HDM1 CEP170B ADGRL3

1.57e-114071921812693553
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 TOR1AIP2 WASHC2C ANK3 CEP162 TUT7 NOB1 DBNL LMTK2 TFIP11 TACC2 WASHC2A WDFY4 KMT2C PTPRR TLE4 VPS35L DZIP3 ZNF638 AFF1 ANKRD12 PEAK1 USP3 TP53BP1 UTP14C

1.80e-0910841922511544199
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP162 DBNL PSD3 LMTK2 TSC2 PFKFB2 REEP2 CEP170 FSIP2 DST MTUS1 STARD9 EIF4G1 ZBTB21 KIF14 AKAP13 SH3BP5L PEAK1 PPIP5K2 R3HDM1 PIBF1 CEP170B

2.91e-098611922236931259
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 CYP4V2 ANK3 PAM16 RABGAP1 TTF1 TRRAP NBPF1 ZNF331 CEP170 ZNF462 KMT2C PTPN4 PTPRB PXDN BRI3BP PTPRR VPS35L ZNF638 AFF1 AKAP13 KATNIP LUZP2 ANKRD12 USP3 SMURF2 CEP170B HTT

1.53e-0814891922828611215
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ZNF148 ANK3 DBNL MED14 TFIP11 SPAG9 TRRAP SYAP1 MBIP CEP170 KMT2C PDCD11 KIF14 PEAK1 TP53BP1 HTT

7.99e-085491921638280479
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

GATD3 MIS18BP1 CEP162 MED14 GON4L SPAG9 MORC2 MBIP UBR7 CCNA2 CEP170 DST DZIP3 ZNF638 KIF14 PIBF1 USP3

1.30e-076451921725281560
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DOCK1 ZNF148 WASHC2C DBNL TACC2 MORC2 SYAP1 IFIT3 EIF4G1 MKI67 ZNF638 AKAP13 BCAR3 HSPB1 TP53BP1

1.54e-075031921516964243
Pubmed

Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry.

CST1 CST2 CST4

1.66e-07319231898352
Pubmed

Immunofluorescence localization of cystatins in human lacrimal gland and in the exorbital lacrimal gland of the rat.

CST1 CST2 CST4

1.66e-07319231471486
Pubmed

Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S.

CST1 CST2 CST4

1.66e-07319231778989
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12 NBPF1 NBPF9

1.84e-0710192422973535
Pubmed

Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T.

CST1 CST2 CST4

6.60e-074192310713450
Pubmed

Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.

CST1 CST2 CST4

6.60e-074192313679380
Pubmed

Human transcription factor protein interaction networks.

ZNF148 RADX GON4L TFIP11 SPAG9 PPARG MORC2 WASHC2A TRRAP MBIP CCNA2 ZNF462 MRPS10 KMT2C DST MRPS2 TLE4 EIF4G1 ZBTB21 MKI67 ZNF638 PDCD11 R3HDM1 TP53BP1

1.34e-0614291922435140242
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

BNC2 TACC2 ADAM12 WDFY4 MTUS1 AKAP13 LUZP2

1.55e-06101192718519826
Pubmed

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2.

CUL1 TUT7 CCNA2 EIF4G1

1.56e-0616192427773672
Pubmed

Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.

CST1 CST2 CST4

1.64e-065192334440840
Pubmed

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development.

CST1 CST2 CST4

1.64e-065192321443774
Pubmed

Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis.

CST1 CST2 CST4

1.64e-065192327079462
Pubmed

Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation.

CST1 CST2 CST4

1.64e-065192320489058
Pubmed

Neuroprotection mediated by cystatin C-loaded extracellular vesicles.

CST1 CST2 CST4

1.64e-065192331367000
Pubmed

Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution.

CST1 CST2 CST4

1.64e-06519238761177
Pubmed

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid Beta Peptide.

CST1 CST2 CST4

1.64e-065192314742906
Pubmed

Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis.

CST1 CST2 CST4

1.64e-065192333754041
Pubmed

Carminerin contributes to chondrocyte calcification during endochondral ossification.

CST1 CST2 CST4

1.64e-065192316680148
Pubmed

Evolution of C, D and S-type cystatins in mammals: an extensive gene duplication in primates.

CST1 CST2 CST4

1.64e-065192325329717
Pubmed

Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice.

CST1 CST2 CST4

1.64e-065192320472891
Pubmed

Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells.

CST1 CST2 CST4

1.64e-065192323671283
Pubmed

Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation.

CST1 CST2 CST4

1.64e-065192317592728
Pubmed

Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.

CST1 CST2 CST4

1.64e-065192332616516
Pubmed

Transforming growth factor beta regulates cystatin C in serum-free mouse embryo (SFME) cells.

CST1 CST2 CST4

1.64e-06519232241983
Pubmed

Strong conservation of the expression of cystatin C gene in choroid plexus.

CST1 CST2 CST4

1.64e-06519231636787
Pubmed

Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse.

CST1 CST2 CST4

1.64e-065192315450354
Pubmed

Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene.

CST1 CST2 CST4

1.64e-065192310748866
Pubmed

Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice.

CST1 CST2 CST4

1.64e-065192315823274
Pubmed

Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice.

CST1 CST2 CST4

1.64e-065192321085595
Pubmed

Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation.

CST1 CST2 CST4

1.64e-065192334914637
Pubmed

A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells.

CST1 CST2 CST4

1.64e-065192316595632
Pubmed

Up-regulation of cystatin C expression in the murine hippocampus following perforant path transections.

CST1 CST2 CST4

1.64e-065192312044447
Pubmed

FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor.

CST1 CST2 CST4

1.64e-065192311144350
Pubmed

Cystatin C triggers neuronal degeneration in a model of multiple system atrophy.

CST1 CST2 CST4

1.64e-065192324405769
Pubmed

Cystatin C is released in association with exosomes: a new tool of neuronal communication which is unbalanced in Alzheimer's disease.

CST1 CST2 CST4

1.64e-065192319773092
Pubmed

Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.

CST1 CST2 CST4

1.64e-065192324570004
Pubmed

Loss of cystatin C regulates permeability and inflammatory pathways in retina.

CST1 CST2 CST4

1.64e-065192336822364
Pubmed

Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice.

CST1 CST2 CST4

1.64e-065192332467129
Pubmed

Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse.

CST1 CST2 CST4

1.64e-065192316242633
Pubmed

Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis.

CST1 CST2 CST4

1.64e-065192333027652
Pubmed

pH-dependent and dynamic interactions of cystatin C with heparan sulfate.

CST1 CST2 CST4

1.64e-065192333580179
Pubmed

CST3 alleviates retinal vascular leakage by regulating the Rap1 signaling pathway.

CST1 CST2 CST4

1.64e-065192339147193
Pubmed

Fertility defects in mice expressing the L68Q variant of human cystatin C: a role for amyloid in male infertility.

CST1 CST2 CST4

1.64e-065192324500719
Pubmed

Control and expression of cystatin C by mouse decidual cultures.

CST1 CST2 CST4

1.64e-065192311803549
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

MTUS1 PTPRR IGHG2 CST1 CST2 CST4 KATNIP HSPB1

1.91e-06149192822664934
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

AKAP6 PPM1E TFIP11 RABGAP1 CCNA2 CEP170 DST SPARCL1

2.11e-06151192817043677
Pubmed

Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy.

CST1 CST2 CST4

3.27e-066192320889561
Pubmed

Cystatin C attenuates insulin signaling transduction by promoting endoplasmic reticulum stress in hepatocytes.

CST1 CST2 CST4

3.27e-066192326592151
Pubmed

Lack of the cysteine protease inhibitor cystatin C promotes atherosclerosis in apolipoprotein E-deficient mice.

CST1 CST2 CST4

3.27e-066192316051881
Pubmed

The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation.

CST1 CST2 CST4

3.27e-066192314607896
Pubmed

Epithelial cell-derived cytokines CST3 and GDF15 as potential therapeutics for pulmonary fibrosis.

CST1 CST2 CST4

3.27e-066192329724997
Pubmed

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity.

CST1 CST2 CST4

3.27e-066192325356866
Pubmed

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

CST1 CST2 CST4

3.27e-066192316365041
Pubmed

Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland.

CST1 CST2 CST4

3.27e-066192311879580
Pubmed

Cystatin C modulates cerebral beta-amyloidosis.

CST1 CST2 CST4

3.27e-066192318026102
Pubmed

Megalin-mediated endocytosis of cystatin C in proximal tubule cells.

CST1 CST2 CST4

3.27e-066192317462596
Pubmed

Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.

CST1 CST2 CST4

3.27e-066192320352108
Pubmed

Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice.

CST1 CST2 CST4

3.27e-066192315653570
Pubmed

Macrophage responses to interferon-gamma are dependent on cystatin C levels.

CST1 CST2 CST4

3.27e-066192319446036
Pubmed

Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy.

CST1 CST2 CST4

3.27e-066192311472890
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 NOB1 MED14 LMTK2 GRID1 TSC2 WASHC2A TRRAP NBPF1 PIKFYVE KMT2C DST EIF4G1 PDCD11 AKAP13 SH3BP5L WDFY3 SMURF2 CEP170B HTT

3.62e-0611051922035748872
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TUT7 SPAG9 TTF1 TRRAP CEP170 DST UTP25 ATAD2B EIF4G1 MKI67 ZNF638 PDCD11 KIF14 MVP TP53BP1

3.95e-066531921522586326
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DOCK1 SLC6A15 PAM16 TACC2 PIKFYVE DST AFF1 WDFY3 PEAK1 HTT

4.65e-062851921034369648
Pubmed

Cystatin C regulates major histocompatibility complex-II-peptide presentation and extracellular signal-regulated kinase-dependent polarizing cytokine production by bone marrow-derived dendritic cells.

CST1 CST2 CST4

5.70e-067192331513306
Pubmed

Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease.

CST1 CST2 CST4

5.70e-067192318957217
Pubmed

Structural organization, expression and chromosomal mapping of the mouse cystatin-C-encoding gene (Cst3).

CST1 CST2 CST4

5.70e-06719237835704
Pubmed

Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.

CST1 CST2 CST4

5.70e-067192323024364
Pubmed

IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.

CST1 CST2 CST4

5.70e-067192321300820
Pubmed

A comprehensive survey of the cadherins expressed in the testes of fetal, immature, and adult mice utilizing the polymerase chain reaction.

CDH3 CDH6 CDH9

5.70e-06719238879495
Pubmed

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein.

CST1 CST2 CST4

5.70e-067192327693425
Pubmed

Structure, alternative splicing and chromosomal localization of the cystatin-related epididymal spermatogenic gene.

CST1 CST2 CST4

5.70e-067192310229662
Pubmed

Plasminogen activator inhibitor-2, but not cystatin C, inhibits the prometastatic activity of tissue inhibitor of metalloproteinases-1 in the liver.

CST1 CST2 CST4

5.70e-067192318681831
Pubmed

Isolation of cystatin C via functional cloning of astrocyte differentiation factors.

CST1 CST2 CST4

5.70e-067192315509901
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF8 FRAS1 NBPF12 MED14 PFKFB2 NBPF11 NBPF1 ZNF462 DST STARD9 NBPF9 NBPF10 L3HYPDH

6.26e-065131921325798074
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TOR1AIP2 ANK3 CEP162 PPM1E PSD3 LMTK2 SLC6A15 SPAG9 ADD2 PTPN4 PTPRB MTUS1 PTPRR MKI67 ZNF638 KIF14 PEAK1 PIBF1 YME1L1

6.37e-0610491921927880917
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ZNF148 SIRT4 PIKFYVE NBPF19 KMT2C DST XIRP2 STARD9 MKI67

6.51e-06233192937704626
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZNF148 WASHC2C MED14 TFIP11 SPAG9 MORC2 TRRAP SYAP1 TLE4 EIF4G1 ZBTB21 MKI67 ZNF638 AFF1 HSPB1 TP53BP1

7.06e-067741921615302935
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TOR1AIP2 FRAS1 ZNF148 ANK3 FRS2 PSD3 SLC6A15 TFIP11 PAM16 PFKM WASHC2A ADD2 MRPS10 BRI3BP MRPS2 PDCD11 AKAP13 DNAJC1 PEAK1 PIBF1 ITM2B YME1L1 TP53BP1

8.73e-0614871922333957083
Pubmed

The embryo's cystatin C and F expression functions as a protective mechanism against the maternal proteinase cathepsin S in mice.

CST1 CST2 CST4

9.09e-068192320093401
Pubmed

Genomic cloning, physical mapping, and expression of human type 2 cystatin genes.

CST1 CST2 CST4

9.09e-06819237690606
Pubmed

Isolation of novel mouse genes associated with ectopic ossification by differential display method using ttw, a mouse model for ectopic ossification.

CST1 CST2 CST4

9.09e-068192311856874
Pubmed

The expression and function of cystatin C and cathepsin B and cathepsin L during mouse embryo implantation and placentation.

CST1 CST2 CST4

9.09e-06819239310336
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TOR1AIP2 CUL1 GATD3 PDSS2 MIS18BP1 PCLO TUT7 PAM16 TSC2 TACC2 SPAG9 RABGAP1 PFKM SYAP1 PIKFYVE MRPS10 DST MRPS2 PDCD11 DNAJC1 R3HDM1 YME1L1 HSPB1

9.61e-0614961922332877691
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

AKAP6 DOCK1 TOR1AIP2 GATD3 ZNF148 ANK3 FRS2 TTF1 SIRT4 CCNA2 ZNF331 CEP170 KMT2C DST VPS35L ZBTB21 ZNF638 ANKRD12 SMURF2 HSPB1 TP53BP1

1.07e-0512931922115342556
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

WASHC2C ANK3 SLC6A15 WASHC2A ADD2 PIKFYVE KIF14 PIBF1 CEP170B

1.18e-05251192929778605
Pubmed

Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.

TSC2 CST1 CST2 CST4

1.22e-052619249226367
Pubmed

Translational deregulation in PDK-1-/- embryonic stem cells.

CST1 CST2 CST4

1.36e-059192316166629
Pubmed

Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring.

AKAP6 AKAP13 RAB32

1.36e-059192312672969
Pubmed

Induced expression of cathepsins and cystatin C in a murine model of demyelination.

CST1 CST2 CST4

1.36e-059192317086443
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

ANK3 PCDHGB5 FRS2 SLC6A15 SYAP1 PEAK1

1.42e-0594192632062451
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MIS18BP1 ANK3 RADX FRS2 SYAP1 MKI67 ZNF638 PEAK1 R3HDM1

1.71e-05263192934702444
Pubmed

Direct mapping of seven genes encoding human type 2 cystatins to a single site located at 20p11.2.

CST1 CST2 CST4

1.93e-051019237896273
InteractionLCA5 interactions

CEP162 GPATCH1 TFIP11 CEP170 BRI3BP MTUS1 KIF14 PIBF1 CEP170B

3.03e-061251919int:LCA5
InteractionYWHAZ interactions

CUL1 CCDC134 CEP162 PSD3 TSC2 TACC2 PFKFB2 PFKM REEP2 MAP3K4 CEP170 FSIP2 PTPN4 DST MTUS1 STARD9 ZBTB21 ZNF638 KIF14 AKAP13 KATNIP SH3BP5L WDFY3 PEAK1 PPIP5K2 R3HDM1 CEP170B HSPB1 TP53BP1 HTT

7.00e-06131919130int:YWHAZ
Cytoband1q21.1

NBPF8 NBPF11 NBPF9 NBPF10

1.37e-046219241q21.1
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF12 NBPF11 NBPF1 NBPF19 NBPF9 NBPF10

1.99e-10231317662
GeneFamilyCystatins, type 2

CST1 CST2 CST4

1.94e-04161313965
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

GPATCH1 AGGF1 TFIP11

5.18e-04221313579
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIS18BP1 GON4L TTF1 DNAJC1

5.86e-04531314532
GeneFamilyWASH complex

WASHC2C WASHC2A

7.67e-04613121331
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP6 AKAP13 RAB32

1.18e-03291313396
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 WDFY3

1.81e-03913121230
GeneFamilyTudor domain containing

TDRD15 TDRD1 TP53BP1

2.41e-03371313780
GeneFamilySmall heat shock proteins

CRYAA HSPB1

2.75e-03111312585
GeneFamilyCD molecules|Type II classical cadherins

CDH6 CDH9

3.86e-031313121186
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK1 CUL1 ZNF148 PSD3 SPAG9 RABGAP1 TRRAP MAP3K4 CEP170 PIKFYVE PTPN4 DST TLE4 ATAD2B ZNF638 KIF14 AFF1 AKAP13 WDFY3 BCAR3 PPIP5K2 R3HDM1 PIBF1 SMURF2 TP53BP1

3.50e-0985619025M4500
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

CUL1 ZNF148 PSD3 CEP170 PIKFYVE DST MTUS1 TLE4 MKI67 ZNF638 KIF14 AFF1 WDFY3 BCAR3 PPIP5K2

5.84e-0930019015M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CUL1 ZNF148 RABGAP1 TRRAP CEP170 PIKFYVE DST TLE4 ATAD2B ZNF638 KIF14 AFF1 BCAR3 R3HDM1 PIBF1 SMURF2

3.28e-0746619016M13522
CoexpressionJOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN

PFKM CST1 CST2 CST4 SPARCL1 ITM2B

1.28e-06481906MM529
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

AKAP6 GRID1 SPAG9 RABGAP1 TARS3 DST DZIP3 ANKRD12 WDFY3

7.67e-081771919e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NBPF12 WASHC2C TUT7 NBPF11 WASHC2A WDFY4 NBPF1 NBPF10

2.09e-071441918984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

BNC2 PDE6A PCDHGB5 ADAM12 ZNF462 PTPRB SLC18A2 SIGLEC6

2.21e-071451918ce307d45425a5191882078f049f85477eec40b69
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

BNC2 PDE6A PCDHGB5 ADAM12 ZNF462 PTPRB SLC18A2 SIGLEC6

2.21e-071451918e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NBPF12 WASHC2C TUT7 NBPF11 WASHC2A WDFY4 NBPF1 NBPF10

6.48e-071671918948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

GATD3 WASHC2C TUT7 WASHC2A NBPF1 IGHG2 VPS35L NBPF10

9.23e-07175191835ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

GATD3 WASHC2C TUT7 WASHC2A NBPF1 IGHG2 VPS35L NBPF10

1.19e-0618119180d07a67e8ee3bca687b378afbc4044434e63556d
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC134 MIS18BP1 RADX PCLO ITGAX BEND6 MKI67 CEP170B

1.40e-061851918b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

PPARG DST UTP25 CFAP221 PDCD11 PPIP5K2 CEP170B TP53BP1

2.00e-06194191888db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PPARG DST UTP25 CFAP221 PDCD11 PPIP5K2 CEP170B TP53BP1

2.00e-061941918a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK1 CUL1 IFI35 ITGAX IFIT3 CCDC112 NMI DST

2.08e-061951918dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK1 CUL1 IFI35 ITGAX IFIT3 CCDC112 NMI DST

2.08e-061951918d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 CENPL EML6 SLC6A15 ZNF331 SPARCL1 CDH6 ADGRL3

2.33e-061981918f261a37dd07976548b897af86df1d1a0dc069889
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 ADAM12 CCNA2 DST MKI67 DNAJC1 BCAR3 CDH6

2.41e-0619919189940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ANK3 PCLO PSD3 DST TLE4 RORB ANKRD12 R3HDM1

2.41e-0619919181b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 PCLO ADGRB3 ADD2 CCDC112 DST DNAJC1 CDH6

2.41e-06199191847466253069d4b1b8f13ce3210f434e60753b38a
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ANK3 PCLO PSD3 DST TLE4 RORB ANKRD12 R3HDM1

2.41e-0619919184bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellSevere-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GATD3 WASHC2C TUT7 SLC6A15 WASHC2A NBPF1 NBPF10

2.48e-061401917683ee5e103f0c68cbbec019249404d381dbc39f3
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C TUT7 NBPF11 WASHC2A NBPF1 UTP25 NBPF10

2.86e-061431917bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C TUT7 NBPF11 WASHC2A WDFY4 NBPF1 NBPF10

4.87e-0615519170a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 ADGRB3 FNDC1 CST2 LUZP2 SPARCL1 CDH6

7.06e-061641917e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

BNC2 PDE6A ADAM12 ZNF462 PTPRB SLC18A2 SIGLEC6

7.34e-0616519175fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

BNC2 PDE6A ADAM12 ZNF462 PTPRB SLC18A2 SIGLEC6

7.34e-06165191793d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD31 CYP2C8 PDE6A ADAM12 SLC18A2 SIGLEC6 RAB32

7.95e-0616719170aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKAP6 MIS18BP1 EML6 IFIT3 TBC1D20 NMI PTPRB

7.95e-061671917774f3264318b002d0df5d06d41d645366038d0bf
ToppCellSevere-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT7 GRID1 NMUR2 NBPF1 XIRP2 NBPF10

8.46e-0611119167021009545178fac1f19f3c429bfedb2f38b680d
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CENPL DNAAF11 CCNA2 BEND6 BRI3BP MKI67

9.63e-061721917ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AKAP6 DOCK1 CUL1 IFIT3 BEND6 DST SIGLEC6

1.08e-051751917c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 ADGRB3 FNDC1 CST2 LUZP2 SPARCL1 CDH6

1.16e-051771917b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD31 TDRD15 ADAM12 SYAP1 ZNF331 SLC18A2 SIGLEC6

1.25e-05179191740441de2d679733ecbf2145fabc3ed65a53310eb
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

WASHC2C NBPF11 WASHC2A IFIT3 NBPF1 DST NBPF10

1.39e-051821917877b6e611626628e709568747512f2827ebb2795
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 ADAM12 ZNF462 SLC18A2 SIGLEC6 CST1 RAB32

1.39e-0518219174cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 ITGAX WDFY4 ZNF331 PIKFYVE NBPF10 HSPB1

1.44e-051831917278064c9f0582463b83bf156d34e77f60187613b
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

AKAP6 ANK3 PSD3 TACC2 DST XIRP2 AKAP13

1.49e-051841917ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC134 MIS18BP1 PCLO ITGAX CCNA2 BEND6 MKI67

1.49e-05184191716aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 BNC2 ANK3 FNDC1 MTUS1 SPARCL1 CDH6

1.60e-0518619176add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPL ADD2 CRB1 MKI67 PSMC3IP LUZP2 CDH6

1.60e-0518619174fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 TACC2 PFKFB2 MBIP MTUS1 CFAP221 AKAP13

1.66e-0518719175df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ANK3 EML6 PPARG B4GALNT2 AFF1 BCAR3

1.66e-051871917e3095455d2f255854f339f6b05fa87852af0700f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 BNC2 ANK3 TACC2 FNDC1 MTUS1 CDH3

1.71e-051881917293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT7 GRID1 NBPF11 NBPF1 PIKFYVE NBPF10

1.75e-05126191642a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

AKAP6 ANK3 PSD3 TACC2 ZNF331 XIRP2 AKAP13

1.77e-0518919170a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

AKAP6 ANK3 PSD3 TACC2 ZNF331 XIRP2 AKAP13

1.83e-05190191793c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellfacs-Thymus-Epithelium-3m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PPARG PTPRB PXDN UNC45B SPARCL1 HSPB1

1.90e-051911917d2311a5b0cf186839000f9f272b6fbc2270ddb44
ToppCellfacs-Thymus-Epithelium-3m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PPARG PTPRB PXDN UNC45B SPARCL1 HSPB1

1.90e-0519119176676ef9aeb890668cb69e67865404061b8467c25
ToppCellfacs-Thymus-Epithelium-3m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK1 PPARG PTPRB PXDN UNC45B SPARCL1 HSPB1

1.90e-051911917a157cee0fbc9dce64308128c3578e7327fa178b7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 TACC2 PFKFB2 MBIP MTUS1 CFAP221 AKAP13

1.96e-05192191729f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 PCLO TACC2 PFKFB2 MBIP MTUS1 CFAP221

1.96e-051921917cc9911e182a289779a2612bc213daae5607689e7
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AIRE WDFY4 ZNF331 PIKFYVE SIGLEC6 BCAR3 HSPB1

1.96e-05192191724797e80b1f5b3ea5a0410caaf57ccf2ae9d716e
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

ANK3 PCLO KCNC2 MTUS1 PTPRR ANKRD12 CDH9

2.10e-051941917b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

ANK3 PCLO KCNC2 MTUS1 PTPRR ANKRD12 CDH9

2.10e-05194191781e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AIRE WDFY4 ZNF331 PIKFYVE SIGLEC6 BCAR3 HSPB1

2.10e-051941917b8f05efb16fbed7317019efc3da7f97f81e90972
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 ITGAX CCNA2 BEND6 MKI67 KIF14 BCAR3

2.10e-051941917effd38e51062b225ecabc7e1c50154e65495d559
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

CUL1 SPAG9 IFI35 SYAP1 IFIT3 KMT2C USP3

2.10e-051941917d1366b169d14011194e61d16b6b0953349febc78
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 ANK3 PSD3 TACC2 DST XIRP2 AKAP13

2.17e-05195191775fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 TACC2 SPAG9 PFKFB2 MBIP MTUS1 AKAP13

2.24e-0519619177e5addaa844e66f8160e05858c341866a80aed23
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 AIRE ITGAX WDFY4 IFIT3 PIKFYVE HSPB1

2.39e-051981917dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 ADAM12 CCNA2 DST MKI67 DNAJC1 CDH6

2.39e-051981917a11ac83dbd69d1c068971266d7c7343d114a6294
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

CENPL CCNA2 PTPN4 PSMC3IP PLAG1 L3HYPDH CEP170B

2.39e-051981917717735d755745439f97ba1b71785c73945dfa9c5
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 BNC2 FNDC1 UNC45B STARD9 SPARCL1 CDH6

2.39e-05198191722e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 TACC2 SPAG9 PFKFB2 MBIP MTUS1 AKAP13

2.47e-0519919172dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellNeuronal-Excitatory-eC(RORB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCLO CCDC168 CFAP221 RORB SPARCL1 DNAJC1 BCAR3

2.55e-0520019178c803a0ce25e140b46036f6aabefc5502601f408
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK3 TACC2 FNDC1 DST MTUS1 SPARCL1 CDH3

2.55e-052001917c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TACC2 FNDC1 DST MTUS1 LUZP2 SPARCL1 CDH6

2.55e-05200191708bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 TACC2 FNDC1 DST MTUS1 SPARCL1 CDH6

2.55e-052001917dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM12 ADD2 CRB1 CCDC112 DST DNAJC1 CDH6

2.55e-052001917553e9612874480f4d2a45671462e266cd0a09321
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

BNC2 PSD3 ADAM12 CASD1 SIGLEC6 PPIP5K2

4.49e-0514919163904f8ce9078de238600ceceee0116af52256a1c
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

WASHC2C ANK3 TUT7 CCDC168 TDRD1 IFIT3

5.02e-0515219162ff0980dfd8d430cca14649151d856edef115720
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 ADGRB3 PTPRR B4GALNT2 SPARCL1 CDH3

5.02e-05152191672499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ANK3 TACC2 MBIP MTUS1 CFAP221 AKAP13

6.01e-05157191631d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 TACC2 MBIP PCDH20 MTUS1 CFAP221

6.44e-051591916e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Thalamus / BrainAtlas - Mouse McCarroll V32

FRAS1 PTPN4 KCNC2 CFAP221 RORB

7.11e-05100191520675fc2ffc5ab63047d38da083b50d470f3db19
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

FRAS1 PTPN4 KCNC2 CFAP221 RORB

7.11e-0510019151de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora|Thalamus / BrainAtlas - Mouse McCarroll V32

FRAS1 PTPN4 KCNC2 CFAP221 RORB

7.11e-051001915ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 TACC2 MBIP AWAT2 ZNF19 MTUS1

7.15e-0516219165c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYCP2 PTPRB UNC45B SPARCL1 ITM2B HSPB1

7.15e-051621916465cb483f41023d6125ea147e16f404d8e8dc9bb
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MIS18BP1 CENPL CCNA2 PTPRB MKI67 KIF14

7.39e-0516319165285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

IFI35 IFIT3 NMI XIRP2 CDH6 ADGRL3

7.65e-051641916362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARG ITGAX IFIT3 FNDC1 BEND6 ADGRL3

7.65e-051641916758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TFIP11 TDRD1 ADAM12 RGS18 SLC18A2 SIGLEC6

8.18e-051661916a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBTFL1 ITGAX WDFY4 RGS18 BEND6 RAB32

8.18e-051661916479391aa6c09aa070b716128ab51b8fec0aea22d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CENPL CCDC168 ZNF462 RGS18 MKI67

8.73e-051681916a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC134 MIS18BP1 CENPL CCNA2 MKI67 KIF14

9.02e-051691916bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MBIP SIRT4 LMOD3 PTPRR TYW5 KATNIP

9.63e-0517119169be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 CENPL NMUR2 CCNA2 MKI67 CDH9

9.63e-05171191605014cf6746e6663e376fdd681f1b43a7081c603
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 CENPL NMUR2 CCNA2 MKI67 CDH9

9.63e-051711916d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C TUT7 NBPF11 WASHC2A NBPF1 NBPF10

9.63e-051711916d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MBIP SIRT4 LMOD3 PTPRR TYW5 KATNIP

9.63e-0517119166a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FRAS1 SLC6A15 CCNA2 BRI3BP LUZP2 HSPB1

9.63e-051711916121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRB3 SLC6A15 REEP2 PTPRR LUZP2 HTR3B

9.94e-051721916a8b33d8ebc56e442a2ad6ac7dafd0c887571bd95
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPL EML6 WDFY4 MKI67 KIF14 MAPK13

9.94e-051721916eba1568d4307e91c94fc616549057cbed8df5840
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

AKAP6 REEP2 FNDC1 SPARCL1 CDH6 ADGRL3

1.03e-041731916a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 PPARG ITGAX CCNA2 MKI67 BCAR3

1.06e-04174191665147b0f8c2ccadd5685430d31081520c157536a
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CCDC168 CCNA2 PTPRB PTPRR MKI67

1.09e-041751916d43ae33a6256606ce848247cad32d74f21b38988
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 SPEF2 ADAM12 LRRC53 CFAP221 DZIP3

1.13e-041761916dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellwk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AIRE SYCP2 PTPRR RORB CDH6 CDH9

1.16e-04177191615a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPATCH1 TSC2 PIKFYVE MRPS10 KATNIP CDH3

1.16e-041771916e1e45956887371b1c18f1eb479dd930031497520
ToppCellfacs-Aorta-Heart-24m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARG PTPRB UNC45B SPARCL1 ITM2B HSPB1

1.16e-041771916c6b955765aee8a196fcf4f7bb16139c95b76dc4e
ToppCelldroplet-Marrow|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNA2 RGS18 MTUS1 MKI67 MAPK13 RAB32

1.16e-0417719160b8a1496c078874def0bfca0268136f1a84b82fd
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 AIRE ITGAX IFIT3 PIKFYVE HSPB1

1.20e-041781916b7374a97c51239782bed658381a02cb1b3d9bf66
Diseasecystatin-SN measurement

CST1 CST2 CST4

1.89e-0591823EFO_0008106
Diseaseurate measurement, bone density

AKAP6 FRAS1 CYP2C8 DDX12P ADGRB3 PSD3 GRID1 PAM16 FSIP2 FNDC1 KIF14 LUZP2 PEAK1

1.32e-0461918213EFO_0003923, EFO_0004531
Diseasecystatin-D measurement

CST1 CST2 CST4

1.47e-04171823EFO_0008103
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 WDFY3

2.25e-0441822DOID:2935 (implicated_via_orthology)
DiseaseAbnormality of refraction

AKAP6 ANK3 PCLO PCDHA1 ZNF462 RGS18 PTPRR AFF1 PLAG1 AKAP13 RORB PEAK1 ADGRL3

2.97e-0467318213HP_0000539
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 TDRD15 PSD3 AFF1 TP53BP1 HTT

3.48e-041501826EFO_0004611, EFO_0020947
Diseasetriglycerides in LDL measurement

TDRD15 PSD3 AFF1 TP53BP1

4.00e-04561824EFO_0022320
Diseaseairway responsiveness measurement

PDSS2 WDFY4 DZIP3

4.25e-04241823EFO_0006897
Diseasetriglycerides in IDL measurement

TDRD15 PSD3 AFF1 TP53BP1

4.58e-04581824EFO_0022149
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

ANKRD31 TDRD15 PSD3 PPARG IFI35 TP53BP1 HTT

4.77e-042221827EFO_0008317, EFO_0020943
DiseaseIntellectual Disability

AKAP6 GON4L TRRAP UBR7 CCNA2 TBC1D20 ZNF462 KMT2C UGP2 HTT

4.87e-0444718210C3714756
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

ANKRD31 TDRD15 PSD3 PPARG IFI35 AFF1 TP53BP1

5.16e-042251827EFO_0008317, EFO_0020947
Diseasefree cholesterol in very large VLDL measurement

ANKRD31 TDRD15 AFF1 TP53BP1

5.55e-04611824EFO_0022274
Diseasetreatment-resistant hypertension

BNC2 EML6 SLC6A15 BRI3BP ITM2B

5.88e-041091825EFO_1002006
Diseasetriglycerides in medium LDL measurement

TDRD15 PSD3 AFF1 TP53BP1

5.91e-04621824EFO_0022322
Diseaselipoprotein A measurement

TDRD15 MAP3K4 FNDC1 AFF1 CDH9

6.65e-041121825EFO_0006925
Diseasetriglycerides in small LDL measurement

TDRD15 PSD3 AFF1 TP53BP1

7.07e-04651824EFO_0022323
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

ANKRD31 TDRD15 PSD3 PPARG IFI35 TP53BP1 HTT

7.37e-042391827EFO_0008317, EFO_0020945
Diseasetotal lipids in small VLDL

ANKRD31 TDRD15 AFF1 TP53BP1

7.93e-04671824EFO_0022148
Diseasetriglycerides in very small VLDL measurement

TDRD15 PSD3 AFF1 TP53BP1

8.38e-04681824EFO_0022144
Diseasefree cholesterol in large VLDL measurement

ANKRD31 TDRD15 AFF1 TP53BP1

8.38e-04681824EFO_0022265
Diseasesynophrys measurement

CEP162 UTP25 PTPRR HTT

8.38e-04681824EFO_0007906
Diseasefactor XI measurement

CYP4V2 ZNF160

1.03e-0381822EFO_0004694
Diseasecystatin-SA measurement

CST1 CST4

1.03e-0381822EFO_0008105
Diseasesarcoma (is_implicated_in)

PTPRB HSPB1

1.03e-0381822DOID:1115 (is_implicated_in)
DiseaseKartagener Syndrome

SPEF2 DNAAF11 CFAP221

1.31e-03351823C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

SPEF2 DNAAF11 CFAP221

1.31e-03351823C4551906
DiseasePolynesian Bronchiectasis

SPEF2 DNAAF11 CFAP221

1.31e-03351823C4317124
Diseasegout

CYP2C8 PSD3 GRID1 ACAD10 DST PIBF1

1.41e-031961826EFO_0004274
Diseaseoppositional defiant disorder measurement

ADAM12 PCDH20 CDH6

1.42e-03361823EFO_0007679
DiseaseGlobal developmental delay

TRRAP TBC1D20 ZNF462 UGP2 PIBF1

1.44e-031331825C0557874
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

ANKRD31 TDRD15 PSD3 TP53BP1

2.01e-03861824EFO_0008595, EFO_0020945
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

CYP2C8 TACC2 SPAG9 LUZP2

2.18e-03881824EFO_0803332
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

TDRD15 PSD3 PPARG MAP3K4 AFF1 TP53BP1

2.24e-032151826EFO_0008317, EFO_0008591
Diseasetriglycerides in large LDL measurement

TDRD15 AFF1 TP53BP1

2.38e-03431823EFO_0022319
DiseaseAbruptio Placentae

TDRD15 ADAM12

2.40e-03121822EFO_1001754
Diseasegait measurement

AKAP6 SLC6A15 PPARG KIF14 HTT

2.43e-031501825EFO_0007680
Diseasesleep duration, low density lipoprotein cholesterol measurement

ANKRD31 TDRD15 R3HDM1 HTT

2.47e-03911824EFO_0004611, EFO_0005271
Diseaseglioblastoma (is_marker_for)

PTPRB KCNC2 PIK3CB

2.54e-03441823DOID:3068 (is_marker_for)
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

TDRD15 PSD3 PPARG IFI35 AFF1 TP53BP1

2.75e-032241826EFO_0004530, EFO_0008317
Diseasesmoking status measurement, ulcerative colitis

GATD3 WDFY4

2.82e-03131822EFO_0000729, EFO_0006527
DiseasePrimary Ciliary Dyskinesia

SPEF2 DNAAF11 CFAP221

3.07e-03471823C4551720
Diseaseurinary bladder cancer (biomarker_via_orthology)

PPARG MKI67

3.28e-03141822DOID:11054 (biomarker_via_orthology)
Diseasetriglyceride measurement, alcohol consumption measurement

TDRD15 PSD3 AFF1 TP53BP1

3.59e-031011824EFO_0004530, EFO_0007878
DiseaseAlzheimer disease, polygenic risk score

FRAS1 PSD3 SLC6A15 TACC2 ITGAX FSIP2 DST PXDN LUZP2 USP3

3.61e-0358618210EFO_0030082, MONDO_0004975
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

TDRD15 PSD3 AFF1 USP3 TP53BP1

3.76e-031661825EFO_0004530, EFO_0004611
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

PSD3 AFF1 TP53BP1

3.87e-03511823EFO_0022302
Diseaseresponse to methotrexate

ZNF148 CDH9

4.29e-03161822GO_0031427
Diseasefourth ventricle volume measurement

ADD2 XIRP2

4.29e-03161822EFO_0010303
Diseasetotal lipids in medium VLDL

TDRD15 AFF1 TP53BP1

4.54e-03541823EFO_0022153
Diseaseplasminogen activator inhibitor 1 measurement

PPARG MAP3K4 LUZP2

4.54e-03541823EFO_0004792
Diseasetriglycerides in medium VLDL measurement

TDRD15 AFF1 TP53BP1

4.79e-03551823EFO_0022155
Diseasedepressive symptom measurement

BNC2 PCLO SLC6A15 PCDHA1 CRB1 ATAD2B LUZP2 CDH9

5.12e-034261828EFO_0007006
Diseasefree cholesterol to total lipids in medium VLDL percentage

ANKRD31 TDRD15 TP53BP1

5.29e-03571823EFO_0022284
Diseasecholesteryl ester measurement

ANKRD31 TDRD15 PSD3 PPARG AFF1 TP53BP1

5.36e-032571826EFO_0010351
DiseaseNuclear non-senile cataract

CRYAA UNC45B

5.42e-03181822C1112705
DiseaseNuclear cataract

CRYAA UNC45B

5.42e-03181822C0392557
Diseasetriglycerides to total lipids in small LDL percentage

PSD3 AFF1 TP53BP1

5.82e-03591823EFO_0022337
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 LMTK2 HTR3B

5.82e-03591823EFO_0001663, MONDO_0005148
Diseasephospholipids in VLDL measurement

TDRD15 AFF1 TP53BP1

5.82e-03591823EFO_0022301
Diseasecholesteryl esters to total lipids in large HDL percentage

PSD3 AFF1 TP53BP1

5.82e-03591823EFO_0022248
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ANKRD31 TDRD15 PSD3 PPARG TP53BP1 HTT

6.09e-032641826EFO_0008317, EFO_0020944
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

PSD3 AFF1 TP53BP1

6.10e-03601823EFO_0021898
Diseasetotal lipids in VLDL measurement

TDRD15 AFF1 TP53BP1

6.10e-03601823EFO_0022314

Protein segments in the cluster

PeptideGeneStartEntry
PNFHKLENKSSIETK

TDRD1

211

Q9BXT4
NINNTPKHFRKDVDV

TTF1

111

Q15361
PEEALKHEKFTIQLQ

CEP170

106

Q5SW79
TKLAPEEHVNTKVQQ

ERICH6B

301

Q5W0A0
KLNVEAVNTHRDKPT

PFKFB2

436

O60825
QHQLKDVKPTPDFVE

CCDC112

56

Q8NEF3
SNPSVEEKLEHLEKQ

BRI3BP

216

Q8WY22
QFSQILEEHKAKVTE

SH3BP5L

231

Q7L8J4
DDSQKPLEIKDNHVE

B4GALNT2

356

Q8NHY0
KELFTNNDPKVIAQH

BCAR3

541

O75815
ENHSEPSHQDVIKVK

BNC2

761

Q6ZN30
PSHQDVIKVKEEFTD

BNC2

766

Q6ZN30
HEKRVPQEQADAAKF

ADGRB3

271

O60242
PEDIQHDKKAFLNDS

HTR3B

191

O95264
PVTHRTDDNIQKVKD

GVQW3

66

Q3ZCU0
LKAETEHNKEVAPQV

AKAP13

991

Q12802
PVVFTVKHIKQSEEN

ADGRL3

786

Q9HAR2
EKVKEHQASLDVNNP

CYP2C8

246

P10632
IHTIKVNDPETAVKE

ACAD10

226

Q6JQN1
VKSFDSKNHPEVLNI

ADAM12

56

O43184
NKKSDVEVQTENHAP

AGGF1

86

Q8N302
NAKIKDEDHSPTFEN

ANKRD12

621

Q6UB98
PEEALKHEKYTSQLQ

CEP170B

106

Q9Y4F5
HKINSDVQPFIKEKT

PDSS2

291

Q86YH6
TLHPDKNKDENAETQ

DNAJC1

91

Q96KC8
LKPEEEHQTDEKQFQ

BEND6

161

Q5SZJ8
DVVPEDKFQETLHLK

AIRE

36

O43918
TRIPDQKFNEHIKDD

R3HDM1

231

Q15032
HQSFPNEENDVDKIK

RAB32

196

Q13637
LNDIASKPSQEHIFK

ITGAX

301

P20702
PQDFEKEIAKLHQQH

PTPN4

181

P29074
DSTKEDIQIQFLPDH

NUDCD1

296

Q96RS6
LQTLHQKPTEEKEFK

PRDM5

186

Q9NQX1
VEIEDINDHTPKFTQ

PCDHGB4

121

Q9UN71
DAPNKSEISKHIEVQ

SPAG9

306

O60271
KQPEEHNFSDTKIIS

RADX

206

Q6NSI4
HENSNLVPKDERFNK

ANKRD31

871

Q8N7Z5
HFQVVNEETPKDKVL

RABGAP1

391

Q9Y3P9
SIDEHFQPKQIVKSL

OGFOD1

186

Q8N543
QKVPQASKDLFHLDE

PCDH20

361

Q8N6Y1
KEITVEHPDTKQVYN

KIF14

386

Q15058
SQKVDSQTIPKHVFE

PTPRB

946

P23467
HEAFNIVKNKTEPVI

KCNC2

251

Q96PR1
EFVGVSHLKQEPQKV

NOB1

96

Q9ULX3
KDSKPNVVSDNVFHI

FRAS1

2536

Q86XX4
FKDPLKQRESEHEQE

KMT2C

1736

Q8NEZ4
ETFTPNRVEKKKLQH

MIS18BP1

146

Q6P0N0
NIKAATNHVTPEEKE

PSMC3IP

146

Q9P2W1
QKLEDPFQKHLNSTE

NMUR2

16

Q9GZQ4
DPANIVHDFNKKLTA

ITM2B

141

Q9Y287
AFDKSEAQVLNPEHK

MTUS1

356

Q9ULD2
PVTFVKSEEKTQEEH

LMOD3

91

Q0VAK6
DPDKIKTQLAQHKEF

DST

6736

Q03001
APADHSILVDQKNEK

KATNIP

611

O60303
EVQNIQPDKDSAHKE

LRRC53

1171

A6NM62
KVFPHAEISQSDKKE

ATAD2B

696

Q9ULI0
VEAHVDQKNKVVTTP

GATD3B

226

A0A0B4J2D5
KILEESSQEQKPEHG

FSIP2

6821

Q5CZC0
KQQSSPLVNKEEEHA

GPATCH1

711

Q9BRR8
APEEQKHDLLKSQVQ

PCLO

1256

Q9Y6V0
DDPKVAEQVLQQKEH

IFI35

86

P80217
LKDQTDFEHRIPKEQ

PFKM

726

P08237
FSQAKQKSHLVDPEI

PEAK1

1556

Q9H792
HSKKIANVPNTEEDE

PDE6A

146

P16499
VQVENKDPKRSHFVL

PIR

226

O00625
QQPFDDSLEHEKLTV

MAPK13

321

O15264
FNDVDKSEDLPSHQK

LMTK2

636

Q8IWU2
VNHFAPDELTVKTKD

HSPB1

101

P04792
EHKLQDSVPENKGIS

MKI67

3076

P46013
KHHTSKIQEFADLPQ

PMS2P1

286

A4D2B8
VEIEDINDHTPKFTQ

PCDHGB5

121

Q9Y5G0
NQPHKNINITFEEDK

NBPF1

221

Q3BBV0
NVKSHPEIQFAEINK

DZIP3

621

Q86Y13
HFEVNDRKDPQETAK

MVP

546

Q14764
IDENDVSKPLQIFHD

MED14

361

O60244
LEPTHNKQDFADAKE

MORC2

421

Q9Y6X9
QDKEKNQEIHLSPIT

PTPRR

261

Q15256
VFHVEVKVKDINDNP

PCDHA1

116

Q9Y5I3
VNPDEAVKVVSDHLK

PPM1E

441

Q8WY54
KKQLINPHVELQFSD

PIKFYVE

1801

Q9Y2I7
HSEGKQIKNLPEETF

HTT

1726

P42858
DQHKTKFGISETQEL

AWAT2

316

Q6E213
NKHENIPFEDKTASV

CASD1

116

Q96PB1
HQEIFEKEFKPTDIS

DOCK1

1706

Q14185
QEDVDPQKVAFLLHK

CENPL

56

Q8N0S6
VAEAIRNHKNEKPEF

CCDC81

391

Q6ZN84
DLNEQFKKHLTNSEP

CUL1

516

Q13616
DTVPDNHRNKFKVIN

FRS2

11

Q8WU20
KEAAASLPKHQQVES

FNDC1

1101

Q4ZHG4
HPEKQFSTDVLKQAI

IFIT3

186

O14879
EVEKVKPQSEKVHQT

GON4L

666

Q3T8J9
RKKIFQEPKSAHQVE

DDX12P

751

Q92771
QVEAKAKDDQTPLHI

ANK3

491

Q12955
VEDIKSSVKGHPQEN

CEP162

316

Q5TB80
GSNPEVQKKVDHELD

CYP4V2

346

Q6ZWL3
SKHSFPDVTNIVQEK

DNAAF11

421

Q86X45
DQGPKTIDQIHKEAE

EIF4G1

996

Q04637
EKHQATINFLKTEVE

LUZP2

106

Q86TE4
RDVKKTQIHFDPEVV

MBIP

136

Q9NS73
VEAHVDQKNKVVTTP

GATD3

226

P0DPI2
HQETPKEDKEVNLEQ

GRID1

861

Q9ULK0
PESEFIIKIHDINDN

CDH6

141

P55285
VEVHNAKTKPREEQF

IGHG2

161

P01859
TKPHQQLKEVSVEER

EML6

1321

Q6ZMW3
VLSESEFHVTPEKNK

CCDC168

6716

Q8NDH2
DVKHFSPEDLTVKVQ

CRYAA

76

P02489
LDTCAFHEQPELQKK

CST2

101

P09228
LDTCAFHEQPELQKK

CST1

101

P01037
KANSKQPAFTIHVDE

CCNA2

91

P20248
HAEKEPEFLNISIQD

CRB1

991

P82279
LDTCAFHEQPELQKK

CST4

101

P01036
KEVFEDKQSVLHNSP

RNF103

551

O00237
PESEFIIKIHDINDN

CDH9

141

Q9ULB4
IIKIHDINDNEPKFT

CDH9

146

Q9ULB4
ISIIVTDQNDHKPKF

CDH3

201

P22223
QESAVHPREIFKQKE

DBNL

251

Q9UJU6
VVRNQEEKIKEFHPT

CFAP221

431

Q4G0U5
FQPNDHKTIKETADE

MAP3K4

1376

Q9Y6R4
IKNTLPSHKEQDHEQ

POLR1D

51

P0DPB5
KESEADSEVKHQPIF

TARS3

116

A2RTX5
SQDPFLQHVNKELKE

UTP25

186

Q68CQ4
QFSNLHVDVPKDLTK

MRPS10

46

P82664
FHDNEKVSEVLPIQK

SPEF2

601

Q9C093
QKVKEEEFPALHLNS

SLC6A15

411

Q9H2J7
HPKDKTEDENKQSFL

TOR1AIP2

81

Q8NFQ8
QHTPKVKNNVEIDEF

TDRD15

51

B5MCY1
IQPHKNIKITFEEDK

NBPF8

186

Q3BBV2
NQPHKNIKITFEEDE

NBPF9

221

P0DPF3
NQPHKNIKITFEEDE

NBPF10

221

Q6P3W6
IQPHKNIKITFEEDK

NBPF11

221

Q86T75
IQPHKNIKITFEEDK

NBPF12

221

Q5TAG4
SNQPHKNIKITFEED

NBPF12

491

Q5TAG4
NQPHRKTKITFEEDK

NBPF19

221

A0A087WUL8
KFKHITPLQEQSKEV

PPARG

291

P37231
EKKLQETPTEANHVQ

SLC9B2

56

Q86UD5
FHKVQPQEPKVTDTE

SIGLEC6

431

O43699
DTVNPDKVDFVHKRV

SIRT4

236

Q9Y6E7
FVEEQHTKKSEAAVP

SYAP1

111

Q96A49
HTPGTDKELVFQDQK

STARD9

2076

Q9P2P6
ENATALHVKFPENKK

PIK3CB

486

P42338
TDFNDKILNEPLKHS

MRPS2

56

Q9Y399
EAVKAQFKINHPDSE

L3HYPDH

221

Q96EM0
EEVKKNHSIILSAPN

STX2

51

P32856
SEDIVLHKNKIPESN

AKAP6

1701

Q13023
PFVQEKTKHKSEVEI

ADD2

386

P35612
VKVHDKETPQDSLVA

AFF1

251

P51825
PQDEKLKDAFSHVVE

CCDC134

96

Q9H6E4
HNQELLKVKTEPVDF

PLAG1

236

Q6DJT9
NEVIPQHLLKTFDEK

SMURF2

606

Q9HAU4
VKTHQEIKLDDSNIP

XIRP2

2921

A4UGR9
IHKPEKAFQQSVEQD

PDCD11

16

Q14690
VQLAKFSKQHVPEEH

UNC45B

596

Q8IWX7
EIAQVPKAHVDEFKS

UGP2

306

Q16851
KLKVNEHGSPVSEDN

ZBTB21

496

Q9ULJ3
EPNKVNHIVTTKDDN

ZBTB21

831

Q9ULJ3
IEDFSFKEPQKNVHD

ZNF160

126

Q9HCG1
EIFNLLHKNKQPVTD

UTP14C

186

Q5TAP6
DAFIKHQQEPTKDPV

VPS35L

591

Q7Z3J2
IPQSQKDHFKSQAEE

UBTFL1

261

P0CB47
QQEPEHGEDTIAKVK

WDFY3

2466

Q8IZQ1
ETRNVEKHQDIPTVK

ZNF19

131

P17023
FVHPTLSNKEKEIDE

REEP2

91

Q9BRK0
DAPKEVNLDFHTKEV

RGS18

146

Q9NS28
SVPEKAAQKEDAQRH

SPEM3

1051

A0A1B0GUW6
NSNVEVLHVTKPDKY

TLE4

681

Q04727
KTELPREHANSKQEE

SPARCL1

221

Q14515
EQEFSHSFKENIPVK

SYCP2

1036

Q9BX26
HSFKENIPVKEENIH

SYCP2

1041

Q9BX26
KTLNVPKEHEDNIFT

PIBF1

721

Q8WXW3
AAHTFEDLKNEIKNP

PXDN

1181

Q92626
EKLQVFKQSHPEIVN

RORB

436

Q92753
HQVFLSPNEDVKEKR

WDFY4

2091

Q6ZS81
YENKSLPTEKNIHEI

ZNF331

51

Q9NQX6
LFSHKLQKDNDPDVD

WASHC2C

846

Q9Y4E1
HLQVPEKSSQKELEA

TACC2

2606

O95359
NEHLKENKVADPVDS

TP53BP1

81

Q12888
SKLSPEEVQKNYEHL

PAM16

66

Q9Y3D7
KTKNIPEAHQDAFKT

YME1L1

256

Q96TA2
YEDAQVPLTNHKKSE

USP3

61

Q9Y6I4
LFSHKLQKDNDPDVD

WASHC2A

846

Q641Q2
KAVKQVQEEDPNTHI

ZBTB17

701

Q13105
HQDSTLKEDVPEQGK

UBR7

231

Q8N806
NDTKQVSREEIHPKE

ZNF462

2441

Q96JM2
KKVAEIHQALNSDPT

TBC1D20

31

Q96BZ9
EIKSNHDKNVIPDEV

ZNF148

526

Q9UQR1
QKPFVEKPVSAEDHN

PPIP5K2

181

O43314
HPDVQTKDDKLKNSV

TUT7

661

Q5VYS8
IKHEKNATEIQTARP

SLC18A2

51

Q05940
EVFLQENKQHLEKTP

PSD3

391

Q9NYI0
AKPIDKQHTDTVVNF

TRRAP

2086

Q9Y4A5
LKEEISQRFKAHPDQ

UBQLN3

46

Q9H347
SDQVLAHPSVKDKFN

TFIP11

691

Q9UBB9
KVELAQSKNDHPTDK

ZNF638

1791

Q14966
VTQENKDQPVISKHE

TBPL2

106

Q6SJ96
PFDQLVQRAAEEKHK

TYW5

81

A2RUC4
HVRQTKEAPAKLESQ

TSC2

1101

P49815
LTIHNKINTAEKPFE

ZNF554

311

Q86TJ5
ILKEHSPDEFIKDEQ

NMI

11

Q13287